Development of pulmonary dendritic cells and macrophage subsets

No Pathway Network information available for Development of pulmonary dendritic cells and macrophage subsets

Pathways in the Development of pulmonary dendritic cells and macrophage subsets SuperPath

#	Name	Source	Genes
1	Development of pulmonary dendritic cells and macrophage subsets	WikiPathways	BATF3 CSF1 CSF2 FLT3LG ID2 IKZF1 IRF4 IRF8 RUNX2 SPI1 STAT3 TCF4 TPO (see all 13) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RUNX2	RUNX Family Transcription Factor 2	Protein Coding	1
2	TPO	Thyroid Peroxidase	Protein Coding	1
3	TCF4	Transcription Factor 4	Protein Coding	1
4	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	1
5	SPI1	Spi-1 Proto-Oncogene	Protein Coding	1
6	BATF3	Basic Leucine Zipper ATF-Like Transcription Factor 3	Protein Coding	1
7	IRF4	Interferon Regulatory Factor 4	Protein Coding	1
8	ID2	Inhibitor Of DNA Binding 2	Protein Coding	1
9	IRF8	Interferon Regulatory Factor 8	Protein Coding	1
10	CSF2	Colony Stimulating Factor 2	Protein Coding	1
11	CSF1	Colony Stimulating Factor 1	Protein Coding	1
12	IKZF1	IKAROS Family Zinc Finger 1	Protein Coding	1
13	FLT3LG	Fms Related Receptor Tyrosine Kinase 3 Ligand	Protein Coding	1

Disorders associated with Development of pulmonary dendritic cells and macrophage subsets SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Skin/hair/eye pigmentation, variation in, 8	Enrichment	IRF4	3.02
2	Immunodeficiency 32a	Enrichment	IRF8	3.02
3	Agammaglobulinemia 10, autosomal dominant	Enrichment	SPI1	3.02
4	Immunodeficiency 131	Enrichment	IRF4	3.02
5	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	3.02
6	Corneal dystrophy, fuchs endothelial, 3	Enrichment	TCF4	3.02
7	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	3.02
8	Immunodeficiency, common variable, 13	Enrichment	IKZF1	3.02
9	Combined immunodeficiency due to dimerization defective ikaros mutation	Enrichment	IKZF1	3.02
10	Immunodeficiency 125	Enrichment	FLT3LG	3.02
11	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	3.02
12	Agammaglobulinemia	Enrichment	SPI1	3.02
13	Early-onset combined immunodeficiency with low ig due to dominant negative ikaros mutation	Enrichment	IKZF1	3.02
14	Whipple disease	Enrichment	IRF4	3.02
15	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	3.02
16	Metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly	Enrichment	RUNX2	2.72
17	Immunodeficiency 32b	Enrichment	IRF8	2.72
18	Diamond-blackfan anemia-like	Enrichment	IKZF1	2.72
19	Thyroid dyshormonogenesis 2a	Enrichment	TPO	2.72
20	Stevens-johnson syndrome	Enrichment	IKZF1	2.72
21	Cleidocranial dysplasia 1	Enrichment	RUNX2	2.54
22	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	STAT3	2.54
23	Breast implant-associated anaplastic large cell lymphoma	Enrichment	STAT3	2.54
24	Hyper ige syndrome	Enrichment	STAT3	2.54
25	Cleidocranial dysplasia	Enrichment	RUNX2	2.54
26	Pitt-hopkins syndrome	Enrichment	TCF4	2.42
27	Cholangitis, primary sclerosing	Enrichment	TCF4	2.32
28	Fuchs' endothelial dystrophy	Enrichment	TCF4	2.32
29	Familial thyroid dyshormonogenesis	Enrichment	TPO	2.24
30	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	IKZF1	2.17
31	Spastic paraplegia 4, autosomal dominant	Enrichment	TCF4	2.12
32	Permanent neonatal diabetes mellitus	Enrichment	STAT3	2.12
33	Autosomal non-syndromic agammaglobulinemia	Enrichment	SPI1	2.02
34	Immune deficiency disease	Enrichment	IKZF1	1.98
35	Leukemia, acute lymphoblastic	Enrichment	IKZF1	1.98
36	Epicanthus	Enrichment	TCF4	1.94
37	Congenital hypothyroidism	Enrichment	TPO	1.94
38	Acute promyelocytic leukemia	Enrichment	STAT3	1.91
39	Stereotypic movement disorder	Enrichment	TCF4	1.91
40	Diffuse large b-cell lymphoma	Enrichment	STAT3	1.74
41	Esophageal atresia/tracheoesophageal fistula	Enrichment	IRF8	1.74
42	Nephrotic syndrome	Enrichment	RUNX2	1.39
43	Autosomal dominant non-syndromic intellectual disability	Enrichment	TCF4	1.33
44	Autism spectrum disorder	Enrichment	TCF4	1.00
45	Microcephaly	Enrichment	TCF4	0.95

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Development of pulmonary dendritic cells and macrophage subsets

Pathway Network for Development of pulmonary dendritic cells and macrophage subsets

Member Pathways for Development of pulmonary dendritic cells and macrophage subsets

Pathways in the Development of pulmonary dendritic cells and macrophage subsets SuperPath

Associated Genes for Development of pulmonary dendritic cells and macrophage subsets

Associated Disorders for Development of pulmonary dendritic cells and macrophage subsets

Disorders associated with Development of pulmonary dendritic cells and macrophage subsets SuperPath

STRING Interaction Network for Development of pulmonary dendritic cells and macrophage subsets

Sources for Development of pulmonary dendritic cells and macrophage subsets