Disruption of postsynaptic signaling by CNV

No Pathway Network information available for Disruption of postsynaptic signaling by CNV

Pathways in the Disruption of postsynaptic signaling by CNV SuperPath

#	Name	Source	Genes
1	Disruption of postsynaptic signaling by CNV	WikiPathways	ARC CAMK2D CAMK2G CYFIP1 DLG1 DLG2 HOMER1 MAPK1 NLGN1 NLGN3 NLGN4X NRXN1 NRXN3 RPH3A RYR2 SYNGAP1 YWHAG (see all 17) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	HOMER1	Homer Scaffold Protein 1	Protein Coding	1
2	NRXN1	Neurexin 1	Protein Coding	1
3	NRXN3	Neurexin 3	Protein Coding	1
4	SYNGAP1	Synaptic Ras GTPase Activating Protein 1	Protein Coding	1
5	CAMK2D	Calcium/Calmodulin Dependent Protein Kinase II Delta	Protein Coding	1
6	YWHAG	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma	Protein Coding	1
7	RYR2	Ryanodine Receptor 2	Protein Coding	1
8	NLGN4X	Neuroligin 4 X-Linked	Protein Coding	1
9	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
10	NLGN3	Neuroligin 3	Protein Coding	1
11	ARC	Activity Regulated Cytoskeleton Associated Protein	Protein Coding	1
12	NLGN1	Neuroligin 1	Protein Coding	1
13	DLG2	Discs Large MAGUK Scaffold Protein 2	Protein Coding	1
14	DLG1	Discs Large MAGUK Scaffold Protein 1	Protein Coding	1
15	CAMK2G	Calcium/Calmodulin Dependent Protein Kinase II Gamma	Protein Coding	1
16	CYFIP1	Cytoplasmic FMR1 Interacting Protein 1	Protein Coding	1
17	RPH3A	Rabphilin 3A	Protein Coding	1

Disorders associated with Disruption of postsynaptic signaling by CNV SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Specific learning disability	Enrichment	MAPK1, YWHAG	4.09
2	Microcephaly	Enrichment	MAPK1, SYNGAP1, YWHAG	3.35
3	Hyperopia, high	Enrichment	NRXN1	2.90
4	Noonan syndrome 13	Enrichment	MAPK1	2.90
5	Pitt-hopkins-like syndrome 2	Enrichment	NRXN1	2.90
6	Autism x-linked 1	Enrichment	NLGN3	2.90
7	Chromosome 2p16.3 deletion syndrome	Enrichment	NRXN1	2.90
8	Developmental and epileptic encephalopathy 56	Enrichment	YWHAG	2.90
9	Autism 20	Enrichment	NLGN1	2.90
10	Nrxn1-related severe neurodevelopmental disorder-motor stereotypies-chronic constipation-sleep-wake cycle disturbance	Enrichment	NRXN1	2.90
11	Intellectual developmental disorder, autosomal dominant 59	Enrichment	CAMK2G	2.90
12	Schizophrenia	Enrichment	DLG2, NRXN1	2.62
13	Ventricular arrhythmias due to cardiac ryanodine receptor calcium release deficiency syndrome	Enrichment	RYR2	2.60
14	Autism x-linked 2	Enrichment	NLGN4X	2.60
15	Intellectual developmental disorder, autosomal recessive 5	Enrichment	SYNGAP1	2.60
16	Ventricular tachycardia, catecholaminergic polymorphic, 2	Enrichment	RYR2	2.60
17	Autism	Enrichment	CAMK2G, NRXN1	2.45
18	Intellectual developmental disorder, autosomal dominant 5	Enrichment	SYNGAP1	2.43
19	Ventricular fibrillation, paroxysmal familial, 1	Enrichment	RYR2	2.30
20	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	2.30
21	Paroxysmal familial ventricular fibrillation	Enrichment	RYR2	2.30
22	Heart conduction disease	Enrichment	RYR2	2.20
23	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	RYR2	2.13
24	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	RYR2	2.00
25	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	RYR2	2.00
26	Myoclonic-atonic epilepsy	Enrichment	SYNGAP1	1.95
27	Hypogonadotropic hypogonadism	Enrichment	NLGN3	1.95
28	Cardiac conduction defect	Enrichment	RYR2	1.83
29	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	RYR2	1.83
30	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	RYR2	1.83
31	Stereotypic movement disorder	Enrichment	SYNGAP1	1.79
32	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	NLGN3	1.76
33	Cleft lip/palate	Enrichment	DLG1	1.76
34	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	RYR2	1.76
35	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	RYR2	1.70
36	Heart, malformation of	Enrichment	MAPK1	1.65
37	Long qt syndrome	Enrichment	RYR2	1.42
38	Left ventricular noncompaction	Enrichment	RYR2	1.37
39	Body mass index quantitative trait locus 11	Enrichment	NRXN1	1.22
40	Undetermined early-onset epileptic encephalopathy	Enrichment	YWHAG	1.17
41	Autism spectrum disorder	Enrichment	NRXN1	0.89
42	Complex neurodevelopmental disorder	Enrichment	SYNGAP1	0.84

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Disruption of postsynaptic signaling by CNV

Pathway Network for Disruption of postsynaptic signaling by CNV

Member Pathways for Disruption of postsynaptic signaling by CNV

Pathways in the Disruption of postsynaptic signaling by CNV SuperPath

Associated Genes for Disruption of postsynaptic signaling by CNV

Associated Disorders for Disruption of postsynaptic signaling by CNV

Disorders associated with Disruption of postsynaptic signaling by CNV SuperPath

STRING Interaction Network for Disruption of postsynaptic signaling by CNV

Sources for Disruption of postsynaptic signaling by CNV