Disturbed pathways in Duchenne Muscular Dystrophy

No Pathway Network information available for Disturbed pathways in Duchenne Muscular Dystrophy

Pathways in the Disturbed pathways in Duchenne Muscular Dystrophy SuperPath

#	Name	Source	Genes
1	Disturbed pathways in Duchenne Muscular Dystrophy	WikiPathways	CACNA1F CACNA1S CACNA2D1 CACNB1 CACNB2 CACNG1 CAPN3 DMD ELANE FKBP1A HSPA9 IL10 IL1A IL6 ITPR1 MPO NFKB1 NFKBIA PLA2G4A PRKAA1 STIM1 TGFB1 TNF TRPC1 TRPC3 TRPC6 (see all 26) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	HSPA9	Heat Shock Protein Family A (Hsp70) Member 9	Protein Coding	1
2	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
3	CAPN3	Calpain 3	Protein Coding	1
4	CACNB2	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 2	Protein Coding	1
5	CACNA2D1	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 1	Protein Coding	1
6	CACNA1S	Calcium Voltage-Gated Channel Subunit Alpha1 S	Protein Coding	1
7	CACNA1F	Calcium Voltage-Gated Channel Subunit Alpha1 F	Protein Coding	1
8	TRPC6	Transient Receptor Potential Cation Channel Subfamily C Member 6	Protein Coding	1
9	TRPC3	Transient Receptor Potential Cation Channel Subfamily C Member 3	Protein Coding	1
10	TRPC1	Transient Receptor Potential Cation Channel Subfamily C Member 1	Protein Coding	1
11	TNF	Tumor Necrosis Factor	Protein Coding	1
12	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
13	STIM1	Stromal Interaction Molecule 1	Protein Coding	1
14	PRKAA1	Protein Kinase AMP-Activated Catalytic Subunit Alpha 1	Protein Coding	1
15	PLA2G4A	Phospholipase A2 Group IVA	Protein Coding	1
16	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	1
17	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
18	MPO	Myeloperoxidase	Protein Coding	1
19	IL10	Interleukin 10	Protein Coding	1
20	IL6	Interleukin 6	Protein Coding	1
21	IL1A	Interleukin 1 Alpha	Protein Coding	1
22	FKBP1A	FKBP Prolyl Isomerase 1A	Protein Coding	1
23	ELANE	Elastase, Neutrophil Expressed	Protein Coding	1
24	DMD	Dystrophin	Protein Coding	1
25	CACNG1	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 1	Protein Coding	1
26	CACNB1	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 1	Protein Coding	1

Disorders associated with Disturbed pathways in Duchenne Muscular Dystrophy SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10, TGFB1	4.28
2	Alzheimer's disease	Enrichment	MPO, TNF	3.57
3	Creatine phosphokinase, elevated serum	Enrichment	CAPN3, DMD	3.38
4	Isolated elevated serum creatine phosphokinase levels	Enrichment	CAPN3, DMD	3.38
5	Muscular dystrophy	Enrichment	CAPN3, DMD	3.02
6	Brugada syndrome	Enrichment	CACNA2D1, CACNB2	2.95
7	Thyrotoxic periodic paralysis 1	Enrichment	CACNA1S	2.72
8	Muscular dystrophy, becker type	Enrichment	DMD	2.72
9	Brugada syndrome 4	Enrichment	CACNB2	2.72
10	Focal segmental glomerulosclerosis 2	Enrichment	TRPC6	2.72
11	Even-plus syndrome	Enrichment	HSPA9	2.72
12	Anemia, sideroblastic, 4	Enrichment	HSPA9	2.72
13	Spinocerebellar ataxia 41	Enrichment	TRPC3	2.72
14	Congenital myopathy 18	Enrichment	CACNA1S	2.72
15	Cardiomyopathy, dilated, 3b	Enrichment	DMD	2.72
16	Graft-versus-host disease	Enrichment	IL10	2.72
17	Cone-rod dystrophy, x-linked, 3	Enrichment	CACNA1F	2.72
18	Immunodeficiency 10	Enrichment	STIM1	2.72
19	Malignant hyperthermia 5	Enrichment	CACNA1S	2.72
20	Cytosolic phospholipase-a2 alpha deficiency associated bleeding disorder	Enrichment	PLA2G4A	2.72
21	Developmental and epileptic encephalopathy 110	Enrichment	CACNA2D1	2.72
22	Gastrointestinal ulceration, recurrent, with dysfunctional platelets	Enrichment	PLA2G4A	2.72
23	Symptomatic form of muscular dystrophy of duchenne and becker in female carriers	Enrichment	DMD	2.72
24	Progressive muscular atrophy	Enrichment	CAPN3	2.72
25	Duchenne and becker muscular dystrophy	Enrichment	DMD	2.72
26	Cryptogenic multifocal ulcerous stenosing enteritis	Enrichment	PLA2G4A	2.72
27	Qualitative or quantitative defects of calpain	Enrichment	CAPN3	2.72
28	Periodic paralysis with transient compartment-like syndrome	Enrichment	CACNA1S	2.72
29	Qualitative or quantitative defects of dystrophin	Enrichment	DMD	2.72
30	Systemic lupus erythematosus	Enrichment	IL10, TNF	2.60
31	Myopathy	Enrichment	CAPN3, DMD	2.58
32	Spinocerebellar ataxia 29	Enrichment	ITPR1	2.42
33	Cyclic neutropenia	Enrichment	ELANE	2.42
34	Camurati-engelmann disease 1	Enrichment	TGFB1	2.42
35	Neutropenia, severe congenital, x-linked	Enrichment	ELANE	2.42
36	Stormorken syndrome	Enrichment	STIM1	2.42
37	Night blindness, congenital stationary, type 2a	Enrichment	CACNA1F	2.42
38	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	2.42
39	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.42
40	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	2.42
41	Immunodeficiency 127	Enrichment	TNF	2.42
42	Camurati-engelmann disease	Enrichment	TGFB1	2.42
43	Ectodermal dysplasia and immune deficiency	Enrichment	NFKBIA	2.42
44	Autosomal recessive sideroblastic anemia	Enrichment	HSPA9	2.42
45	Common variable immunodeficiency 12	Enrichment	NFKB1	2.42
46	Neutropenia, severe congenital, 1, autosomal dominant	Enrichment	ELANE	2.24
47	Gillespie syndrome	Enrichment	ITPR1	2.24
48	Muscular dystrophy, duchenne type	Enrichment	DMD	2.24
49	Psoriatic arthritis	Enrichment	TNF	2.24
50	Nasopharyngeal carcinoma	Enrichment	NFKBIA	2.24
51	Muscular dystrophy, limb-girdle, autosomal dominant 4	Enrichment	CAPN3	2.24
52	Autosomal recessive limb-girdle muscular dystrophy type 2a	Enrichment	CAPN3	2.24
53	Migraine without aura	Enrichment	TNF	2.24
54	Thyrotoxic periodic paralysis	Enrichment	CACNA1S	2.24
55	Kaposi sarcoma	Enrichment	IL6	2.12
56	Myeloperoxidase deficiency	Enrichment	MPO	2.12
57	Aland island eye disease	Enrichment	CACNA1F	2.12
58	Myopathy, autophagic vacuolar, infantile-onset	Enrichment	STIM1	2.12
59	Spinocerebellar ataxia 15	Enrichment	ITPR1	2.12
60	Malignant hyperthermia	Enrichment	CACNA1S	2.12
61	Cerebral malaria	Enrichment	TNF	2.12
62	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	2.12
63	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	2.02
64	Amblyopia	Enrichment	CACNA1F	2.02
65	Cardiac arrest	Enrichment	CACNA2D1	2.02
66	Autosomal recessive limb-girdle muscular dystrophy type 2b	Enrichment	CAPN3	2.02
67	Vascular dementia	Enrichment	TNF	2.02
68	Autosomal dominant severe congenital neutropenia	Enrichment	ELANE	2.02
69	Congenital short qt syndrome	Enrichment	CACNA2D1	2.02
70	Hypokalemic periodic paralysis, type 1	Enrichment	CACNA1S	1.94
71	Muscular dystrophy, limb-girdle, autosomal recessive 1	Enrichment	CAPN3	1.94
72	Type 1 diabetes mellitus	Enrichment	IL6	1.94
73	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.94
74	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	1.94
75	Brugada syndrome 1	Enrichment	CACNA2D1	1.87
76	Neutropenia	Enrichment	ELANE	1.87
77	Alzheimer's disease 1	Enrichment	MPO	1.87
78	Common variable immunodeficiency	Enrichment	NFKB1	1.87
79	Myopathy, tubular aggregate, 1	Enrichment	STIM1	1.82
80	Congenital muscular dystrophy	Enrichment	CAPN3	1.82
81	Rheumatoid arthritis	Enrichment	IL10	1.77
82	Inflammatory bowel disease 1	Enrichment	IL6	1.77
83	Limb-girdle muscular dystrophy	Enrichment	CAPN3	1.77
84	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.72
85	Migraine with or without aura 1	Enrichment	CAPN3	1.68
86	Pectus excavatum	Enrichment	DMD	1.68
87	Asthma	Enrichment	TNF	1.68
88	Atrial heart septal defect	Enrichment	DMD	1.68
89	Interatrial communication	Enrichment	DMD	1.68
90	Muscular dystrophy, limb-girdle, autosomal recessive 2	Enrichment	CAPN3	1.64
91	Multiple sclerosis	Enrichment	ITPR1	1.58
92	Cone-rod dystrophy 6	Enrichment	CACNA1F	1.58
93	Myopia	Enrichment	CACNA1F	1.55
94	Anterior segment dysgenesis	Enrichment	ITPR1	1.55
95	Gliosarcoma	Enrichment	NFKBIA	1.52
96	Alzheimer disease, familial, 1	Enrichment	MPO	1.49
97	Giant cell glioblastoma	Enrichment	NFKBIA	1.49
98	Beckwith-wiedemann syndrome	Enrichment	DMD	1.47
99	Human immunodeficiency virus type 1	Enrichment	IL10	1.47
100	Arteriovenous malformations of the brain	Enrichment	IL6	1.45
101	Behcet syndrome	Enrichment	IL10	1.45
102	Congenital myopathy	Enrichment	CACNA1S	1.45
103	Autosomal recessive limb-girdle muscular dystrophy	Enrichment	CAPN3	1.45
104	Focal segmental glomerulosclerosis	Enrichment	TRPC6	1.42
105	Centronuclear myopathy	Enrichment	CACNA1S	1.40
106	Malaria	Enrichment	TNF	1.36
107	Congenital stationary night blindness	Enrichment	CACNA1F	1.36
108	Autoinflammatory disease	Enrichment	ELANE	1.35
109	Long qt syndrome	Enrichment	CACNA1S	1.24
110	Cystic fibrosis	Enrichment	TGFB1	1.22
111	Familial hypertrophic cardiomyopathy	Enrichment	DMD	1.21
112	Genetic steroid-resistant nephrotic syndrome	Enrichment	TRPC6	1.20
113	Fanconi anemia, complementation group a	Enrichment	DMD	1.19
114	Eye disease	Enrichment	CACNA1F	1.19
115	Non-syndromic x-linked intellectual disability	Enrichment	DMD	1.18
116	Type 2 diabetes mellitus	Enrichment	IL6	1.11
117	Nephrotic syndrome	Enrichment	TRPC6	1.10
118	Optic atrophy plus syndrome	Enrichment	CACNA1F	1.09
119	Spastic ataxia	Enrichment	ITPR1	1.01
120	Familial isolated dilated cardiomyopathy	Enrichment	DMD	1.01
121	Undetermined early-onset epileptic encephalopathy	Enrichment	CACNA2D1	0.99
122	Schizophrenia	Enrichment	DMD	0.97
123	Cone-rod dystrophy 2	Enrichment	CACNA1F	0.91
124	Autism	Enrichment	DMD	0.89
125	Breast cancer	Enrichment	CACNA2D1	0.87
126	Dilated cardiomyopathy	Enrichment	DMD	0.85
127	Colorectal cancer	Enrichment	DMD	0.81
128	Retinitis pigmentosa	Enrichment	CACNA1F	0.47
129	Hereditary retinal dystrophy	Enrichment	CACNA1F	0.37
130	Fundus dystrophy	Enrichment	CACNA1F	0.37

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Disturbed pathways in Duchenne Muscular Dystrophy

Pathway Network for Disturbed pathways in Duchenne Muscular Dystrophy

Member Pathways for Disturbed pathways in Duchenne Muscular Dystrophy

Pathways in the Disturbed pathways in Duchenne Muscular Dystrophy SuperPath

Associated Genes for Disturbed pathways in Duchenne Muscular Dystrophy

Associated Disorders for Disturbed pathways in Duchenne Muscular Dystrophy

Disorders associated with Disturbed pathways in Duchenne Muscular Dystrophy SuperPath

STRING Interaction Network for Disturbed pathways in Duchenne Muscular Dystrophy

Sources for Disturbed pathways in Duchenne Muscular Dystrophy