PathCards :: DNA Double-Strand Break Repair Pathway and related pathways

Pathway network for DNA Double-Strand Break Repair SuperPath

11 Pathways in the DNA Double-Strand Break Repair SuperPath

	HDR through MMEJ (alt-NHEJ)		Processing of DNA double-strand break ends
	Non-homologous end joining		Homology Directed Repair
	HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)		DNA Double-Strand Break Repair
	Non-homologous end-joining		Chk1/Chk2(Cds1) mediated inactivation of Cyclin B-Cdk1 complex
	DNA damage_DNA-damage-induced responses		DNA Repair
	G2/M DNA damage checkpoint

329 Genes in the DNA Double-Strand Break Repair SuperPath

MRE11	RAD50	CHEK1	NBN	RBBP8	MIR4741	ATM	ATR	BRCA1	MDC1	BARD1	BLM
DNA2	H2AX	H2BC5	H2BC3	HUS1	RAD1	RAD9A	RAD17	RFC2	RFC3	RFC4	RFC5
RPA1	RPA2	RPA3	TOP3A	TP53BP1	UBE2N	UBE2V2	SUMO1	NSD2	WRN	H3-4	H4C9
H2BC8	H2BC13	H2BC15	H2BC14	H2BC7	H2BC6	H2BC9	H2BC10	H2BC4	H2BC17	H2BC21	H4C1
H4C4	H4C6	H4C12	H4C11	H4C3	H4C8	H4C2	H4C5	H4C13	H4C14	HERC2	H2BC11
RNF8	EXO1	BABAM2	KAT5	TOPBP1	BABAM1	PIAS4	UIMC1	BRCC3	RMI1	RHNO1	BRIP1
ATRIP	ABRAXAS1	H2BC12	RMI2	H4-16	H2BU1	RAD9B	RNF168	H2BC1	H4C15	LOC102724334	FEN1
CCNA2	CDK2	PPP4C	RNF4	RPS27A	SUMO2	UBA52	UBB	UBC	UBE2I	CCNA1	TIMELESS
SIRT6	TIPIN	CLSPN	PPP4R2	PRKDC	ABL1	PARP1	LIG3	XRCC1	PARP2	POLQ	XRCC6
XRCC4	XRCC5	NHEJ1	BRCA2	ERCC1	ERCC4	PCNA	POLD1	POLD2	POLE	POLE2	POLH
RAD51	RAD51C	RAD51B	RAD51D	RAD52	RFC1	XRCC2	XRCC3	RAD51AP1	POLD3	SPIDR	POLK
RTEL1	POLE3	POLE4	POLD4	SLX1B	PALB2	MUS81	SLX4	EME1	EME2	GEN1	SLX1A
TP53	CHEK2	LIG4	POLL	POLM	DCLRE1C	APBB1	EYA4	EYA1	EYA2	EYA3	KPNA2
PPP5C	MAPK8	BAP1	SMARCA5	BAZ1B	KDM4A	PAXIP1	KDM4B	TDP2	RIF1	TDP1	MIR6838
CCNB1	CDK1	CDC25C	SFN	WEE1	YWHAB	YWHAE	YWHAG	YWHAH	YWHAZ	YWHAQ	DNTT
ACTB	ACTL6A	APEX1	CCNH	CDK7	CETN2	ERCC8	DDB1	DDB2	EP300	ERCC2	ERCC3
ERCC5	ERCC6	FANCA	FANCC	FANCD2	FANCE	FANCB	FANCF	FANCG	GPS1	MSH6	GTF2H1
GTF2H2	GTF2H3	GTF2H4	HMGN1	LIG1	MGMT	MLH1	MNAT1	MPG	MSH2	MSH3	MUTYH
NFRKB	NTHL1	OGG1	PMS2	POLB	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G
POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	RAD23A	RAD23B	REV3L	SUMO3	TCEA1	TDG	UBA7
UBE2B	UFD1	UNG	USP1	VCP	XPA	XPC	YY1	TRIM25	USP7	ELL	CUL4B
CUL4A	PARG	COPS3	PIAS1	RUVBL1	MBD4	USP10	UBE2L6	COPS2	CHD1L	ISG15	AQR
PCLAF	DCLRE1A	RBX1	PIAS3	MCRS1	PPIE	MAD2L2	COPS8	ASCC3	COPS6	COPS5	POLI
PNKP	FAN1	SMUG1	RCHY1	ZBTB32	PRPF19	UBE2T	TFPT	COPS7A	ASCC1	COPS4	REV1
DTL	INO80	RNF111	ALKBH5	INO80D	FANCL	FANCI	NPLOC4	RAD18	XAB2	ISY1	UVSSA
FANCM	COPS7B	DCLRE1B	FTO	NEIL1	ACTR5	FAAP100	INO80B	SPRTN	ASCC2	USP45	FAAP24
ZNF830	ACTR8	ALKBH2	USP43	INO80C	FAAP20	CENPX	ALKBH3	NEIL2	INO80E	POLN	CENPS
GTF2H5	MIR1281	MIR3614	MIR5193	MIR6764

*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.

STRING interaction network for DNA Double-Strand Break Repair SuperPath