PathCards :: DNA Double-Strand Break Repair Pathway and related pathways

Pathway network for DNA Double-Strand Break Repair SuperPath

11 Pathways in the DNA Double-Strand Break Repair SuperPath

	Chk1/Chk2(Cds1) mediated inactivation of Cyclin B-Cdk1 complex		HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)
	Non-homologous end-joining		Non-homologous end joining
	DNA damage_DNA-damage-induced responses		Processing of DNA double-strand break ends
	Homology Directed Repair		G2/M DNA damage checkpoint
	DNA Repair		DNA Double-Strand Break Repair
	HDR through MMEJ (alt-NHEJ)

331 Genes in the DNA Double-Strand Break Repair SuperPath

MRE11	RAD50	CHEK1	ATM	ATR	BRCA1	NBN	RBBP8	MDC1	MIR4741	BARD1	BLM
DNA2	H2AFX	HIST1H2BD	HIST1H2BB	HUS1	RAD1	RAD9A	RAD17	RFC2	RFC3	RFC4	RFC5
RPA1	RPA2	RPA3	TOP3A	TP53BP1	UBE2N	UBE2V2	SUMO1	NSD2	WRN	HIST3H3	HIST1H4I
HIST1H2BG	HIST1H2BL	HIST1H2BN	HIST1H2BM	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BI	HIST1H2BC	HIST1H2BO	HIST2H2BE	HIST1H4A
HIST1H4D	HIST1H4F	HIST1H4K	HIST1H4J	HIST1H4C	HIST1H4H	HIST1H4B	HIST1H4E	HIST1H4L	HIST2H4A	HERC2	HIST1H2BJ
RNF8	EXO1	BABAM2	KAT5	TOPBP1	BABAM1	PIAS4	UIMC1	BRCC3	RMI1	RHNO1	BRIP1
ATRIP	ABRAXAS1	HIST1H2BK	RMI2	HIST4H4	HIST3H2BB	RAD9B	RNF168	HIST1H2BA	HIST2H4B	LOC102724334	ABL1
CCNA2	CDK2	PPP4C	RNF4	RPS27A	SUMO2	UBA52	UBB	UBC	UBE2I	CCNA1	TIMELESS
SIRT6	TIPIN	CLSPN	PPP4R2	FEN1	PRKDC	BRCA2	ERCC1	ERCC4	PCNA	POLD1	POLD2
POLE	POLE2	POLH	RAD51	RAD51C	RAD51B	RAD51D	RAD52	RFC1	XRCC2	XRCC3	RAD51AP1
POLD3	SPIDR	POLK	RTEL1	POLE3	POLE4	POLD4	SLX1B	PALB2	MUS81	SLX4	EME1
EME2	GEN1	SLX1A	LOC105369236	XRCC6	XRCC4	XRCC5	NHEJ1	TP53	CHEK2	PARP1	LIG3
XRCC1	PARP2	POLQ	POLL	POLM	LIG4	DCLRE1C	CCNB1	CDK1	CDC25C	SFN	WEE1
YWHAB	YWHAE	YWHAG	YWHAH	YWHAZ	YWHAQ	APBB1	EYA4	EYA1	EYA2	EYA3	KPNA2
PPP5C	MAPK8	BAP1	SMARCA5	BAZ1B	KDM4A	PAXIP1	KDM4B	TDP2	RIF1	TDP1	MIR6838
DNTT	ACTB	ACTL6A	APEX1	CCNH	CDK7	CETN2	ERCC8	DDB1	DDB2	EP300	ERCC2
ERCC3	ERCC5	ERCC6	FANCA	FANCC	FANCD2	FANCE	FANCB	FANCF	FANCG	GPS1	MSH6
GTF2H1	GTF2H2	GTF2H3	GTF2H4	HMGN1	LIG1	MGMT	MLH1	MNAT1	MPG	MSH2	MSH3
MUTYH	NFRKB	NTHL1	OGG1	PMS2	POLB	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F
POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	RAD23A	RAD23B	REV3L	SUMO3	TCEA1	TDG
UBA7	UBE2B	UFD1	UNG	USP1	VCP	XPA	XPC	YY1	TRIM25	USP7	ELL
CUL4B	CUL4A	PARG	COPS3	PIAS1	RUVBL1	MBD4	USP10	UBE2L6	COPS2	CHD1L	ISG15
AQR	PCLAF	DCLRE1A	RBX1	PIAS3	MCRS1	PPIE	MAD2L2	COPS8	ASCC3	COPS6	COPS5
POLI	PNKP	FAN1	SMUG1	RCHY1	ZBTB32	PRPF19	UBE2T	TFPT	COPS7A	ASCC1	COPS4
REV1	DTL	INO80	RNF111	ALKBH5	INO80D	FANCL	FANCI	NPLOC4	RAD18	XAB2	ISY1
UVSSA	FANCM	COPS7B	DCLRE1B	FTO	NEIL1	ACTR5	FAAP100	INO80B	SPRTN	ASCC2	USP45
FAAP24	ZNF830	ACTR8	ALKBH2	USP43	INO80C	FAAP20	CENPX	ALKBH3	NEIL2	INO80E	POLN
CENPS	GTF2H5	MIR1281	MIR3614	MIR5193	MIR6764	LOC107984056

*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.

STRING interaction network for DNA Double-Strand Break Repair SuperPath