DNA Replication

Pathway network for the DNA Replication SuperPath

Sources:

Reactome

Pathways in the DNA Replication SuperPath

#	Name	Source	Genes
1	DNA Replication	Reactome	ADRM1 ANAPC1 ANAPC10 ANAPC11 ANAPC15 ANAPC16 ANAPC2 ANAPC4 ANAPC5 ANAPC7 CCNA1 CCNA2 CCNE1 CCNE2 CDC16 CDC23 CDC26 CDC27 CDC45 CDC6 CDC7 CDK2 CDT1 CUL1 DBF4 DNA2 EXOG FEN1 FZR1 GINS1 GINS2 GINS3 GINS4 GMNN H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AJ H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-3A H3-3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 KPNA1 KPNA6 KPNB1 LIG1 LIG3 MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 MGME1 ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 PCNA POLA1 POLA2 POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLG POLG2 POLRMT PRIM1 PRIM2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RBX1 RFC1 RFC2 RFC3 RFC4 RFC5 RNASEH1 RPA1 RPA2 RPA3 RPA4 RPS27A SEM1 SKP1 SKP2 SSBP1 TOP3A TWNK UBA52 UBB UBC UBE2C UBE2D1 UBE2E1 UBE2S (see all 184) (see less)
2	Transcriptional regulation by RUNX1	Reactome	ABL1 ACTL6A ACTL6B ADRM1 AGO1 AGO2 AGO3 AGO4 ARID1A ARID1B ARID2 ASH2L AUTS2 AXIN1 BLK BMI1 CBFB CBX2 CBX4 CBX6 CBX8 CCND1 CCND2 CCND3 CCNH CDK6 CDK7 CLDN5 COMMD3-BMI1 CR1 CREBBP CSF2 CSNK2A1 CSNK2A2 CSNK2B CTLA4 CTSK CTSL CTSV DPY30 ELF1 ELF2 EP300 ESR1 FOXP3 GATA1 GATA2 GATA3 GP1BA GPAM H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AJ H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-3A H3-3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HDAC1 HIPK2 IFNG IL2 IL2RA IL3 ITCH ITGA2B KAT2B KCTD6 KMT2A KMT2B KMT2C KMT2D LDB1 LGALS3 LIFR LMO1 LMO2 MNAT1 MOV10 MYB MYL9 NFATC2 NFE2 NR4A3 PAX5 PBRM1 PCGF5 PF4 PHC1 PHC2 PHC3 PML PRKCB PRMT1 PRMT6 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTPN11 RBBP5 RING1 RNF2 RPS27A RSPO3 RUNX1 RUNX2 RYBP SCMH1 SEM1 SERPINB13 SETD1A SETD1B SIN3A SIN3B SMARCA2 SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCD2 SMARCD3 SMARCE1 SOCS3 SOCS4 SPI1 SRC TAL1 TCF12 TCF3 THBS1 TJP1 TNFRSF18 TNRC6A TNRC6B TNRC6C UBA52 UBB UBC WDR5 YAF2 YAP1 ZFPM1 (see all 221) (see less)
3	DNA Replication Pre-Initiation	Reactome	ADRM1 ANAPC1 ANAPC10 ANAPC11 ANAPC15 ANAPC16 ANAPC2 ANAPC4 ANAPC5 ANAPC7 CDC16 CDC23 CDC26 CDC27 CDC45 CDC6 CDC7 CDK2 CDT1 DBF4 FZR1 GMNN H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AJ H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-3A H3-3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 KPNA1 KPNA6 KPNB1 MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 POLA1 POLA2 POLE POLE2 POLE3 POLE4 PRIM1 PRIM2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPA1 RPA2 RPA3 RPA4 RPS27A SEM1 UBA52 UBB UBC UBE2C UBE2D1 UBE2E1 UBE2S (see all 149) (see less)
4	Assembly of the pre-replicative complex	Reactome	ADRM1 ANAPC1 ANAPC10 ANAPC11 ANAPC15 ANAPC16 ANAPC2 ANAPC4 ANAPC5 ANAPC7 CDC16 CDC23 CDC26 CDC27 CDC6 CDT1 FZR1 GMNN H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AJ H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-3A H3-3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 KPNA1 KPNA6 KPNB1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A SEM1 UBA52 UBB UBC UBE2C UBE2D1 UBE2E1 UBE2S (see all 132) (see less)
5	RUNX1 regulates transcription of genes involved in differentiation of HSCs	Reactome	ABL1 ADRM1 CBFB CCNH CDK7 GATA1 GATA2 GATA3 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AJ H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-3A H3-3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 ITCH KMT2A LDB1 LMO1 LMO2 MNAT1 MYB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A RUNX1 SEM1 SPI1 TAL1 TCF12 TCF3 UBA52 UBB UBC YAP1 (see all 115) (see less)
6	Strand-asynchronous mitochondrial DNA replication	Reactome	EXOG LIG3 MGME1 POLG POLG2 POLRMT RNASEH1 SSBP1 TOP3A TWNK (see all 10) (see less)

Gene overlap in member pathways for DNA Replication SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PSMD14	Proteasome 26S Subunit, Non-ATPase 14	Protein Coding	5
2	ADRM1	ADRM1 26S Proteasome Ubiquitin Receptor	Protein Coding	5
3	H4C16	H4 Histone 16	Protein Coding	5
4	H3C14	H3 Clustered Histone 14	Protein Coding	5
5	H2BC26	H2B Clustered Histone 26	Protein Coding	5
6	H2BC1	H2B Clustered Histone 1	Protein Coding	5
7	H2AC8	H2A Clustered Histone 8	Protein Coding	5
8	H2AC7	H2A Clustered Histone 7	Protein Coding	5
9	H2AX	H2A.X Variant Histone	Protein Coding	5
10	H2BC5	H2B Clustered Histone 5	Protein Coding	5
11	H2BC3	H2B Clustered Histone 3	Protein Coding	5
12	H3-3A	H3.3 Histone A	Protein Coding	5
13	H3-3B	H3.3 Histone B	Protein Coding	5
14	H3C15	H3 Clustered Histone 15	Protein Coding	5
15	H2AB1	H2A.B Variant Histone 1	Protein Coding	5
16	H2BC12L	H2B Clustered Histone 12 Like	Protein Coding	5
17	H4C15	H4 Clustered Histone 15	Protein Coding	5
18	H2AJ	H2A.J Histone	Protein Coding	5
19	PSMA1	Proteasome 20S Subunit Alpha 1	Protein Coding	5
20	PSMA2	Proteasome 20S Subunit Alpha 2	Protein Coding	5
21	PSMA3	Proteasome 20S Subunit Alpha 3	Protein Coding	5
22	PSMA4	Proteasome 20S Subunit Alpha 4	Protein Coding	5
23	PSMA5	Proteasome 20S Subunit Alpha 5	Protein Coding	5
24	PSMA6	Proteasome 20S Subunit Alpha 6	Protein Coding	5
25	PSMA7	Proteasome 20S Subunit Alpha 7	Protein Coding	5
26	PSMB1	Proteasome 20S Subunit Beta 1	Protein Coding	5
27	PSMB2	Proteasome 20S Subunit Beta 2	Protein Coding	5
28	PSMB3	Proteasome 20S Subunit Beta 3	Protein Coding	5
29	PSMB4	Proteasome 20S Subunit Beta 4	Protein Coding	5
30	PSMB5	Proteasome 20S Subunit Beta 5	Protein Coding	5
31	PSMB6	Proteasome 20S Subunit Beta 6	Protein Coding	5
32	PSMB7	Proteasome 20S Subunit Beta 7	Protein Coding	5
33	PSMC1	Proteasome 26S Subunit, ATPase 1	Protein Coding	5
34	PSMC2	Proteasome 26S Subunit, ATPase 2	Protein Coding	5
35	PSMC3	Proteasome 26S Subunit, ATPase 3	Protein Coding	5
36	PSMC4	Proteasome 26S Subunit, ATPase 4	Protein Coding	5
37	PSMC5	Proteasome 26S Subunit, ATPase 5	Protein Coding	5
38	PSMC6	Proteasome 26S Subunit, ATPase 6	Protein Coding	5
39	PSMD1	Proteasome 26S Subunit, Non-ATPase 1	Protein Coding	5
40	PSMD2	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 2	Protein Coding	5
41	PSMD3	Proteasome 26S Subunit, Non-ATPase 3	Protein Coding	5
42	PSMD7	Proteasome 26S Subunit, Non-ATPase 7	Protein Coding	5
43	PSMD8	Proteasome 26S Subunit, Non-ATPase 8	Protein Coding	5
44	PSMD11	Proteasome 26S Subunit, Non-ATPase 11	Protein Coding	5
45	PSMD12	Proteasome 26S Subunit, Non-ATPase 12	Protein Coding	5
46	PSMD13	Proteasome 26S Subunit, Non-ATPase 13	Protein Coding	5
47	RPS27A	Ribosomal Protein S27a	Protein Coding	5
48	H3C13	H3 Clustered Histone 13	Protein Coding	5
49	H2AC19	H2A Clustered Histone 19	Protein Coding	5
50	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	5
51	UBB	Ubiquitin B	Protein Coding	5
52	UBC	Ubiquitin C	Protein Coding	5
53	SEM1	SEM1 26S Proteasome Subunit	Protein Coding	5
54	H4C9	H4 Clustered Histone 9	Protein Coding	5
55	H2AC14	H2A Clustered Histone 14	Protein Coding	5
56	H2AC6	H2A Clustered Histone 6	Protein Coding	5
57	H2AC4	H2A Clustered Histone 4	Protein Coding	5
58	H2AC18	H2A Clustered Histone 18	Protein Coding	5
59	H2AC20	H2A Clustered Histone 20	Protein Coding	5
60	H2BC8	H2B Clustered Histone 8	Protein Coding	5
61	H2BC13	H2B Clustered Histone 13	Protein Coding	5
62	H2BC15	H2B Clustered Histone 15	Protein Coding	5
63	H2BC14	H2B Clustered Histone 14	Protein Coding	5
64	H2BC7	H2B Clustered Histone 7	Protein Coding	5
65	H2BC6	H2B Clustered Histone 6	Protein Coding	5
66	H2BC9	H2B Clustered Histone 9	Protein Coding	5
67	H2BC10	H2B Clustered Histone 10	Protein Coding	5
68	H2BC4	H2B Clustered Histone 4	Protein Coding	5
69	H2BC17	H2B Clustered Histone 17	Protein Coding	5
70	H2BC21	H2B Clustered Histone 21	Protein Coding	5
71	H3C1	H3 Clustered Histone 1	Protein Coding	5
72	H3C4	H3 Clustered Histone 4	Protein Coding	5
73	H3C3	H3 Clustered Histone 3	Protein Coding	5
74	H3C6	H3 Clustered Histone 6	Protein Coding	5
75	H3C11	H3 Clustered Histone 11	Protein Coding	5
76	H3C8	H3 Clustered Histone 8	Protein Coding	5
77	H3C12	H3 Clustered Histone 12	Protein Coding	5
78	H3C10	H3 Clustered Histone 10	Protein Coding	5
79	H3C2	H3 Clustered Histone 2	Protein Coding	5
80	H4C1	H4 Clustered Histone 1	Protein Coding	5
81	H4C4	H4 Clustered Histone 4	Protein Coding	5
82	H4C6	H4 Clustered Histone 6	Protein Coding	5
83	H4C12	H4 Clustered Histone 12	Protein Coding	5
84	H4C11	H4 Clustered Histone 11	Protein Coding	5
85	H4C3	H4 Clustered Histone 3	Protein Coding	5
86	H4C8	H4 Clustered Histone 8	Protein Coding	5
87	H4C2	H4 Clustered Histone 2	Protein Coding	5
88	H4C5	H4 Clustered Histone 5	Protein Coding	5
89	H4C13	H4 Clustered Histone 13	Protein Coding	5
90	H4C14	H4 Clustered Histone 14	Protein Coding	5
91	H2BC12	H2B Clustered Histone 12	Protein Coding	5
92	H3C7	H3 Clustered Histone 7	Protein Coding	5
93	H2BC11	H2B Clustered Histone 11	Protein Coding	5
94	H2AZ2	H2A.Z Variant Histone 2	Protein Coding	5
95	PSMD6	Proteasome 26S Subunit, Non-ATPase 6	Protein Coding	5
96	ANAPC10	Anaphase Promoting Complex Subunit 10	Protein Coding	3
97	UBE2C	Ubiquitin Conjugating Enzyme E2 C	Protein Coding	3
98	ANAPC16	Anaphase Promoting Complex Subunit 16	Protein Coding	3
99	ORC6	Origin Recognition Complex Subunit 6	Protein Coding	3
100	ORC3	Origin Recognition Complex Subunit 3	Protein Coding	3
101	KPNA6	Karyopherin Subunit Alpha 6	Protein Coding	3
102	CDC26	Cell Division Cycle 26	Protein Coding	3
103	ANAPC15	Anaphase Promoting Complex Subunit 15	Protein Coding	3
104	UBE2S	Ubiquitin Conjugating Enzyme E2 S	Protein Coding	3
105	ANAPC2	Anaphase Promoting Complex Subunit 2	Protein Coding	3
106	ANAPC4	Anaphase Promoting Complex Subunit 4	Protein Coding	3
107	KPNA1	Karyopherin Subunit Alpha 1	Protein Coding	3
108	KPNB1	Karyopherin Subunit Beta 1	Protein Coding	3
109	MCM2	Minichromosome Maintenance Complex Component 2	Protein Coding	3
110	MCM3	Minichromosome Maintenance Complex Component 3	Protein Coding	3
111	MCM4	Minichromosome Maintenance Complex Component 4	Protein Coding	3
112	MCM5	Minichromosome Maintenance Complex Component 5	Protein Coding	3
113	MCM6	Minichromosome Maintenance Complex Component 6	Protein Coding	3
114	MCM7	Minichromosome Maintenance Complex Component 7	Protein Coding	3
115	ORC1	Origin Recognition Complex Subunit 1	Protein Coding	3
116	ORC2	Origin Recognition Complex Subunit 2	Protein Coding	3
117	ORC4	Origin Recognition Complex Subunit 4	Protein Coding	3
118	ORC5	Origin Recognition Complex Subunit 5	Protein Coding	3
119	GMNN	Geminin DNA Replication Inhibitor	Protein Coding	3
120	FZR1	Fizzy And Cell Division Cycle 20 Related 1	Protein Coding	3
121	ANAPC5	Anaphase Promoting Complex Subunit 5	Protein Coding	3
122	ANAPC7	Anaphase Promoting Complex Subunit 7	Protein Coding	3
123	ANAPC11	Anaphase Promoting Complex Subunit 11	Protein Coding	3
124	ANAPC1	Anaphase Promoting Complex Subunit 1	Protein Coding	3
125	UBE2D1	Ubiquitin Conjugating Enzyme E2 D1	Protein Coding	3
126	UBE2E1	Ubiquitin Conjugating Enzyme E2 E1	Protein Coding	3
127	CDT1	Chromatin Licensing And DNA Replication Factor 1	Protein Coding	3
128	MCM8	Minichromosome Maintenance 8 Homologous Recombination Repair Factor	Protein Coding	3
129	CDC23	Cell Division Cycle 23	Protein Coding	3
130	CDC16	Cell Division Cycle 16	Protein Coding	3
131	CDC6	Cell Division Cycle 6	Protein Coding	3
132	CDC27	Cell Division Cycle 27	Protein Coding	3
133	CDK2	Cyclin Dependent Kinase 2	Protein Coding	2
134	DBF4	DBF4-CDC7 Kinase Regulatory Subunit	Protein Coding	2
135	POLG2	DNA Polymerase Gamma 2, Accessory Subunit	Protein Coding	2
136	POLA2	DNA Polymerase Alpha 2, Accessory Subunit	Protein Coding	2
137	RNASEH1	Ribonuclease H1	Protein Coding	2
138	RPA4	Replication Protein A4	Protein Coding	2
139	LIG3	DNA Ligase 3	Protein Coding	2
140	POLE3	DNA Polymerase Epsilon 3, Accessory Subunit	Protein Coding	2
141	POLA1	DNA Polymerase Alpha 1, Catalytic Subunit	Protein Coding	2
142	POLE	DNA Polymerase Epsilon, Catalytic Subunit	Protein Coding	2
143	POLE2	DNA Polymerase Epsilon 2, Accessory Subunit	Protein Coding	2
144	POLG	DNA Polymerase Gamma, Catalytic Subunit	Protein Coding	2
145	POLRMT	RNA Polymerase Mitochondrial	Protein Coding	2
146	MCM10	Minichromosome Maintenance 10 Replication Initiation Factor	Protein Coding	2
147	PRIM1	DNA Primase Subunit 1	Protein Coding	2
148	PRIM2	DNA Primase Subunit 2	Protein Coding	2
149	TWNK	Twinkle MtDNA Helicase	Protein Coding	2
150	POLE4	DNA Polymerase Epsilon 4, Accessory Subunit	Protein Coding	2
151	RPA1	Replication Protein A1	Protein Coding	2
152	RPA2	Replication Protein A2	Protein Coding	2
153	RPA3	Replication Protein A3	Protein Coding	2
154	SSBP1	Single Stranded DNA Binding Protein 1	Protein Coding	2
155	TOP3A	DNA Topoisomerase III Alpha	Protein Coding	2
156	CDC7	Cell Division Cycle 7	Protein Coding	2
157	CDC45	Cell Division Cycle 45	Protein Coding	2
158	MGME1	Mitochondrial Genome Maintenance Exonuclease 1	Protein Coding	2
159	EXOG	Exo/Endonuclease G	Protein Coding	2
160	CDK7	Cyclin Dependent Kinase 7	Protein Coding	2
161	YAP1	Yes1 Associated Transcriptional Regulator	Protein Coding	2
162	ABL1	ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase	Protein Coding	2
163	GATA1	GATA Binding Protein 1	Protein Coding	2
164	GATA2	GATA Binding Protein 2~Name Same As:- HGNC:18350	Protein Coding	2
165	GATA3	GATA Binding Protein 3	Protein Coding	2
166	LMO1	LIM Domain Only 1	Protein Coding	2
167	LMO2	LIM Domain Only 2	Protein Coding	2
168	KMT2A	Lysine Methyltransferase 2A	Protein Coding	2
169	MNAT1	MNAT1 Component Of CDK Activating Kinase	Protein Coding	2
170	MYB	MYB Proto-Oncogene, Transcription Factor	Protein Coding	2
171	SPI1	Spi-1 Proto-Oncogene	Protein Coding	2
172	TAL1	TAL BHLH Transcription Factor 1, Erythroid Differentiation Factor	Protein Coding	2
173	TCF3	Transcription Factor 3	Protein Coding	2
174	TCF12	Transcription Factor 12	Protein Coding	2
175	ITCH	Itchy E3 Ubiquitin Protein Ligase	Protein Coding	2
176	RUNX1	RUNX Family Transcription Factor 1	Protein Coding	2
177	CBFB	Core-Binding Factor Subunit Beta	Protein Coding	2
178	LDB1	LIM Domain Binding 1	Protein Coding	2
179	CCNH	Cyclin H	Protein Coding	2
180	POLD3	DNA Polymerase Delta 3, Accessory Subunit	Protein Coding	1
181	DNA2	DNA Replication Helicase/Nuclease 2	Protein Coding	1
182	FEN1	Flap Structure-Specific Endonuclease 1	Protein Coding	1
183	LIG1	DNA Ligase 1	Protein Coding	1
184	PCNA	Proliferating Cell Nuclear Antigen	Protein Coding	1
185	GINS2	GINS Complex Subunit 2	Protein Coding	1
186	POLD1	DNA Polymerase Delta 1, Catalytic Subunit	Protein Coding	1
187	POLD2	DNA Polymerase Delta 2, Accessory Subunit	Protein Coding	1
188	POLD4	DNA Polymerase Delta 4, Accessory Subunit	Protein Coding	1
189	RFC1	Replication Factor C Subunit 1	Protein Coding	1
190	RFC2	Replication Factor C Subunit 2	Protein Coding	1
191	RFC3	Replication Factor C Subunit 3	Protein Coding	1
192	RFC4	Replication Factor C Subunit 4	Protein Coding	1
193	RFC5	Replication Factor C Subunit 5	Protein Coding	1
194	GINS3	GINS Complex Subunit 3	Protein Coding	1
195	SKP1	S-Phase Kinase Associated Protein 1	Protein Coding	1
196	SKP2	S-Phase Kinase Associated Protein 2	Protein Coding	1
197	GINS4	GINS Complex Subunit 4	Protein Coding	1
198	CUL1	Cullin 1	Protein Coding	1
199	CCNA2	Cyclin A2	Protein Coding	1
200	CCNA1	Cyclin A1	Protein Coding	1
201	CCNE1	Cyclin E1	Protein Coding	1
202	CCNE2	Cyclin E2	Protein Coding	1
203	GINS1	GINS Complex Subunit 1	Protein Coding	1
204	RBX1	Ring-Box 1	Protein Coding	1
205	COMMD3-BMI1	COMMD3-BMI1 Readthrough	Protein Coding	1
206	YAF2	YY1 Associated Factor 2	Protein Coding	1
207	CDK6	Cyclin Dependent Kinase 6	Protein Coding	1
208	MYL9	Myosin Light Chain 9	Protein Coding	1
209	WDR5	WD Repeat Domain 5	Protein Coding	1
210	SOCS4	Suppressor Of Cytokine Signaling 4	Protein Coding	1
211	CR1	Complement C3b/C4b Receptor 1 (Knops Blood Group)	Protein Coding	1
212	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
213	CSF2	Colony Stimulating Factor 2	Protein Coding	1
214	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	1
215	CSNK2A2	Casein Kinase 2 Alpha 2	Protein Coding	1
216	CSNK2B	Casein Kinase 2 Beta	Protein Coding	1
217	CTLA4	Cytotoxic T-Lymphocyte Associated Protein 4	Protein Coding	1
218	CTSK	Cathepsin K	Protein Coding	1
219	CTSL	Cathepsin L	Protein Coding	1
220	CTSV	Cathepsin V	Protein Coding	1
221	ZFPM1	Zinc Finger Protein, FOG Family Member 1	Protein Coding	1
222	PHC1	Polyhomeotic Homolog 1	Protein Coding	1
223	PHC2	Polyhomeotic Homolog 2	Protein Coding	1
224	AGO3	Argonaute RISC Catalytic Component 3	Protein Coding	1
225	AGO4	Argonaute RISC Component 4	Protein Coding	1
226	ARID2	AT-Rich Interaction Domain 2	Protein Coding	1
227	ELF1	E74 Like ETS Transcription Factor 1	Protein Coding	1
228	ELF2	E74 Like ETS Transcription Factor 2	Protein Coding	1
229	KCTD6	Potassium Channel Tetramerization Domain Containing 6	Protein Coding	1
230	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
231	ESR1	Estrogen Receptor 1	Protein Coding	1
232	SCMH1	Scm Polycomb Group Protein Homolog 1	Protein Coding	1
233	SETD1B	SET Domain Containing 1B, Histone Lysine Methyltransferase	Protein Coding	1
234	TNRC6B	Trinucleotide Repeat Containing Adaptor 6B	Protein Coding	1
235	SIN3B	SIN3 Transcription Regulator Family Member B	Protein Coding	1
236	RYBP	RING1 And YY1 Binding Protein	Protein Coding	1
237	CBX6	Chromobox 6	Protein Coding	1
238	SIN3A	SIN3 Transcription Regulator Family Member A	Protein Coding	1
239	AUTS2	Activator Of Transcription And Developmental Regulator AUTS2	Protein Coding	1
240	AGO1	Argonaute RISC Component 1	Protein Coding	1
241	AGO2	Argonaute RISC Catalytic Component 2	Protein Coding	1
242	TNRC6A	Trinucleotide Repeat Containing Adaptor 6A	Protein Coding	1
243	GP1BA	Glycoprotein Ib Platelet Subunit Alpha	Protein Coding	1
244	HIPK2	Homeodomain Interacting Protein Kinase 2	Protein Coding	1
245	HDAC1	Histone Deacetylase 1	Protein Coding	1
246	PRMT1	Protein Arginine Methyltransferase 1	Protein Coding	1
247	IFNG	Interferon Gamma	Protein Coding	1
248	IL2	Interleukin 2	Protein Coding	1
249	IL2RA	Interleukin 2 Receptor Subunit Alpha	Protein Coding	1
250	IL3	Interleukin 3	Protein Coding	1
251	ITGA2B	Integrin Subunit Alpha 2b	Protein Coding	1
252	LGALS3	Galectin 3	Protein Coding	1
253	LIFR	LIF Receptor Subunit Alpha	Protein Coding	1
254	MOV10	Mov10 RNA Helicase	Protein Coding	1
255	NFATC2	Nuclear Factor Of Activated T Cells 2	Protein Coding	1
256	NFE2	Nuclear Factor, Erythroid 2	Protein Coding	1
257	PAX5	Paired Box 5	Protein Coding	1
258	FOXP3	Forkhead Box P3~Name Same As:- HGNC:13781	Protein Coding	1
259	ACTL6B	Actin Like 6B	Protein Coding	1
260	PF4	Platelet Factor 4	Protein Coding	1
261	SERPINB13	Serpin Family B Member 13	Protein Coding	1
262	PML	PML Nuclear Body Scaffold	Protein Coding	1
263	PRMT6	Protein Arginine Methyltransferase 6	Protein Coding	1
264	PBRM1	Polybromo 1	Protein Coding	1
265	PRKCB	Protein Kinase C Beta	Protein Coding	1
266	CBX8	Chromobox 8	Protein Coding	1
267	ARID1B	AT-Rich Interaction Domain 1B	Protein Coding	1
268	GPAM	Glycerol-3-Phosphate Acyltransferase, Mitochondrial	Protein Coding	1
269	TNRC6C	Trinucleotide Repeat Containing Adaptor 6C	Protein Coding	1
270	PTPN11	Protein Tyrosine Phosphatase Non-Receptor Type 11	Protein Coding	1
271	KMT2C	Lysine Methyltransferase 2C	Protein Coding	1
272	RBBP5	RB Binding Protein 5, Histone Lysine Methyltransferase Complex Subunit	Protein Coding	1
273	CCND1	Cyclin D1	Protein Coding	1
274	RING1	Ring Finger Protein 1	Protein Coding	1
275	RNF2	Ring Finger Protein 2	Protein Coding	1
276	BLK	BLK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
277	BMI1	BMI1 Proto-Oncogene, Polycomb Ring Finger	Protein Coding	1
278	SMARCA2	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 2	Protein Coding	1
279	SMARCA4	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 4	Protein Coding	1
280	SMARCB1	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit B1	Protein Coding	1
281	SMARCC1	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit C1	Protein Coding	1
282	SMARCC2	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit C2	Protein Coding	1
283	SMARCD1	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit D1	Protein Coding	1
284	SMARCD2	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit D2	Protein Coding	1
285	SMARCD3	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit D3	Protein Coding	1
286	SMARCE1	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit E1	Protein Coding	1
287	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
288	THBS1	Thrombospondin 1	Protein Coding	1
289	TJP1	Tight Junction Protein 1	Protein Coding	1
290	CLDN5	Claudin 5	Protein Coding	1
291	PHC3	Polyhomeotic Homolog 3	Protein Coding	1
292	NR4A3	Nuclear Receptor Subfamily 4 Group A Member 3	Protein Coding	1
293	KMT2D	Lysine Methyltransferase 2D	Protein Coding	1
294	ARID1A	AT-Rich Interaction Domain 1A	Protein Coding	1
295	AXIN1	Axin 1	Protein Coding	1
296	PCGF5	Polycomb Group Ring Finger 5	Protein Coding	1
297	DPY30	Dpy-30 Histone Methyltransferase Complex Regulatory Subunit	Protein Coding	1
298	CBX2	Chromobox 2	Protein Coding	1
299	RSPO3	R-Spondin 3	Protein Coding	1
300	CBX4	Chromobox 4	Protein Coding	1
301	ACTL6A	Actin Like 6A	Protein Coding	1
302	RUNX2	RUNX Family Transcription Factor 2	Protein Coding	1
303	TNFRSF18	TNF Receptor Superfamily Member 18	Protein Coding	1
304	KAT2B	Lysine Acetyltransferase 2B	Protein Coding	1
305	CCND2	Cyclin D2	Protein Coding	1
306	CCND3	Cyclin D3	Protein Coding	1
307	SOCS3	Suppressor Of Cytokine Signaling 3	Protein Coding	1
308	ASH2L	ASH2 Like, Histone Lysine Methyltransferase Complex Subunit	Protein Coding	1
309	SETD1A	SET Domain Containing 1A, Histone Lysine Methyltransferase	Protein Coding	1
310	KMT2B	Lysine Methyltransferase 2B	Protein Coding	1

Disorders associated with DNA Replication SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Meier-gorlin syndrome 1	Enrichment	CDC45, CDC6, CDT1, GMNN, MCM7, ORC1, ORC4, ORC6	16.00
2	Coffin-siris syndrome 1	Enrichment	ARID1A, ARID1B, ARID2, SMARCA4, SMARCB1, SMARCC2, SMARCD1, SMARCE1	10.19
3	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1	Enrichment	POLG, POLG2, TWNK	8.24
4	Complex neurodevelopmental disorder	Enrichment	ACTL6A, ACTL6B, AGO1, AGO2, CSNK2A1, H4C3, H4C5, H4C9, KMT2B, PSMD12, RNF2, SETD1A, TNRC6B	6.95
5	Autism spectrum disorder	Enrichment	ACTL6B, ARID1B, AUTS2, CSNK2A1, CSNK2B, KMT2A, KMT2C, PTPN11, SETD1A, SMARCB1, TCF12, TNRC6B	6.69
6	Tessadori-bicknell-van haaften neurodevelopmental syndrome 4	Enrichment	H2BC12, H4C1, H4C9	6.23
7	Sensory ataxic neuropathy, dysarthria, and ophthalmoparesis	Enrichment	POLG, TWNK	5.31
8	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	LIG3, POLG	4.76
9	Mitochondrial disease	Enrichment	POLG, TOP3A, TWNK	4.53
10	Myeloma, multiple	Enrichment	CCND1, CREBBP, H3C1, KMT2C, KMT2D, TCF3, YAP1	4.49
11	Tessadori-bicknell-van haaften neurodevelopmental syndrome 1	Enrichment	H4C1, H4C3	4.15
12	Tessadori-bicknell-van haaften neurodevelopmental syndrome 2	Enrichment	H4C1, H4C11	4.15
13	Acute basophilic leukemia	Enrichment	GATA1, MYB	4.15
14	Bryant-li-bhoj neurodevelopmental syndrome 2	Enrichment	H3-3A, H3-3B	4.15
15	Rare genetic intellectual disability	Enrichment	ARID1B, CREBBP, EP300, KMT2A	4.09
16	Thrombocytopenia	Enrichment	GATA1, GP1BA, ITGA2B, PTPN11, RUNX1, SRC	3.92
17	Microcephaly	Enrichment	ABL1, ARID1A, ARID1B, AUTS2, EP300, KMT2A, KMT2D, PSMC3, PTPN11	3.74
18	Tessadori-bicknell-van haaften neurodevelopmental syndrome 3	Enrichment	H4C1, H4C5	3.67
19	Rhabdoid tumor predisposition syndrome	Enrichment	SMARCA4, SMARCB1	3.58
20	Witteveen-kolk syndrome	Enrichment	SIN3A, SIN3B	3.58
21	B-lymphoblastic leukemia/lymphoma with t(7;9)(q11.2;p13.2)	Enrichment	AUTS2, PAX5	3.58
22	Polymerase proofreading-related polyposis	Enrichment	POLD1, POLE	3.26
23	Acute megakaryocytic leukemia	Enrichment	GATA1, KMT2A	3.15
24	Optic atrophy 13 with retinal and foveal abnormalities	Enrichment	SSBP1	3.13
25	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 3	Enrichment	TWNK	3.13
26	Perrault syndrome 5	Enrichment	TWNK	3.13
27	Combined oxidative phosphorylation deficiency 55	Enrichment	POLRMT	3.13
28	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 5	Enrichment	TOP3A	3.13
29	Mitochondrial dna depletion syndrome, hepatocerebrorenal form	Enrichment	TWNK	3.13
30	Childhood myocerebrohepatopathy spectrum	Enrichment	POLG	3.13
31	Spinocerebellar ataxia with epilepsy	Enrichment	POLG	3.13
32	Recessive mitochondrial ataxia syndrome	Enrichment	POLG	3.13
33	Nail disorder, nonsyndromic congenital, 9	Enrichment	ARID1B, CTSK	3.11
34	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ABL1, MYB, TAL1	3.03
35	Leukemia, chronic myeloid	Enrichment	ABL1, RUNX1	2.84
36	Fanconi anemia, complementation group i	Enrichment	POLG	2.83
37	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 4	Enrichment	POLG2	2.83
38	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 2	Enrichment	RNASEH1	2.83
39	Mitochondrial dna depletion syndrome 16b	Enrichment	POLG2	2.83
40	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 1	Enrichment	POLG	2.83
41	Mitochondrial dna depletion syndrome 11	Enrichment	MGME1	2.83
42	Depressive disorder	Enrichment	TWNK	2.83
43	Polg-related disorders	Enrichment	POLG	2.83
44	Microcephaly, growth restriction, and increased sister chromatid exchange 2	Enrichment	TOP3A	2.83
45	Mitochondrial dna depletion syndrome 16	Enrichment	POLG2	2.83
46	Autosomal recessive progressive external ophthalmoplegia	Enrichment	POLG	2.83
47	Mitochondrial dna depletion syndrome 20	Enrichment	LIG3	2.83
48	Nicolaides-baraitser syndrome	Enrichment	ARID1B, SMARCA2	2.81
49	Intellectual developmental disorder, autosomal dominant 26	Enrichment	AUTS2, KMT2D	2.81
50	Blepharophimosis	Enrichment	ARID1B, SMARCA2	2.81
51	Smarca2-related nicolaides-baraitser syndrome	Enrichment	ARID1B, SMARCA2	2.81
52	Corpus callosum, agenesis of	Enrichment	ARID1B, AUTS2, CREBBP	2.77
53	Isolated corpus callosum agenesis	Enrichment	ARID1B, AUTS2, CREBBP	2.77
54	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	ARID1B, AUTS2, CREBBP	2.77
55	Glioma susceptibility 1	Enrichment	H3-3A, H3C1	2.71
56	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	ARID1A, ARID1B, AUTS2	2.69
57	Mitochondrial dna depletion syndrome 7	Enrichment	TWNK	2.66
58	Chronic progressive external ophthalmoplegia	Enrichment	TWNK	2.66
59	Idiopathic camptocormia	Enrichment	POLG	2.66
60	Acute liver failure	Enrichment	POLG2	2.66
61	Chondrosarcoma, extraskeletal myxoid	Enrichment	NR4A3, TCF12	2.59
62	Lymphoma	Enrichment	KMT2D, PTPN11	2.59
63	Generalized epilepsy	Enrichment	POLG	2.53
64	Autosomal non-syndromic agammaglobulinemia	Enrichment	SPI1, TCF3	2.51
65	Kabuki syndrome 1	Enrichment	KMT2A, KMT2D	2.42
66	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	2.42
67	Wiedemann-steiner syndrome	Enrichment	ARID1B, KMT2A	2.42
68	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	2.42
69	Patent ductus arteriosus	Enrichment	PSMC3, PTPN11	2.42
70	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	GP1BA, ITGA2B	2.42
71	Hypertrichosis	Enrichment	ARID1B, CREBBP	2.42
72	Machado-joseph disease	Enrichment	POLG	2.35
73	Mitochondrial dna depletion syndrome 1	Enrichment	POLG	2.35
74	Mitochondrial dna depletion syndrome	Enrichment	POLG	2.35
75	Leukemia, acute myeloid	Enrichment	GATA2, KMT2A, RUNX1	2.33
76	Mitochondrial dna depletion syndrome 4a	Enrichment	POLG	2.29
77	Third-degree atrioventricular block	Enrichment	TWNK	2.29
78	Mitochondrial dna depletion syndrome 4b	Enrichment	POLG	2.23
79	Perrault syndrome 2	Enrichment	TWNK	2.18
80	Autosomal dominant cerebellar ataxia	Enrichment	POLG	2.18
81	Scoliosis	Enrichment	CREBBP, CTSK, PTPN11	2.17
82	Neuroblastoma	Enrichment	LMO1, SMARCA4	2.16
83	Anemia, congenital, nonspherocytic hemolytic, 9	Enrichment	GATA1	2.07
84	Thrombocytopenia, x-linked, with or without dyserythropoietic anemia	Enrichment	GATA1	2.07
85	Thrombocytopenia with beta-thalassemia, x-linked	Enrichment	GATA1	2.07
86	Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or impaired intellectual development	Enrichment	YAP1	2.07
87	Agammaglobulinemia 10, autosomal dominant	Enrichment	SPI1	2.07
88	Neurodevelopmental disorder with microcephaly, hypotonia, and absent language	Enrichment	PSMB1	2.07
89	Agammaglobulinemia 8b, autosomal recessive	Enrichment	TCF3	2.07
90	Anemia, x-linked, with or without neutropenia and/or platelet abnormalities	Enrichment	GATA1	2.07
91	Stankiewicz-isidor syndrome	Enrichment	PSMD12	2.07
92	Lymphedema, primary, with myelodysplasia	Enrichment	GATA2	2.07
93	Uveal coloboma-cleft lip and palate-intellectual disability	Enrichment	YAP1	2.07
94	Deafness, cataract, impaired intellectual development, and polyneuropathy	Enrichment	PSMC3	2.07
95	Agammaglobulinemia 8a, autosomal dominant	Enrichment	TCF3	2.07
96	Autoimmune disease, multisystem, with facial dysmorphism	Enrichment	ITCH	2.07
97	Immunodeficiency 21	Enrichment	GATA2	2.07
98	Craniosynostosis 3	Enrichment	TCF12	2.07
99	Bryant-li-bhoj neurodevelopmental syndrome 1	Enrichment	H3-3A	2.07
100	Deafness-lymphedema-leukemia syndrome	Enrichment	GATA2	2.07
101	Acute megakaryoblastic leukemia in children with down syndrome	Enrichment	GATA1	2.07
102	Acute myeloid leukemia with mll rearrangement	Enrichment	KMT2A	2.07
103	Syndromic multisystem autoimmune disease due to itch deficiency	Enrichment	ITCH	2.07
104	Thrombocytopenia with congenital dyserythropoietic anemia	Enrichment	GATA1	2.07
105	Agammaglobulinemia	Enrichment	SPI1	2.07
106	Hypogonadotropic hypogonadism 26 with or without anosmia	Enrichment	TCF12	2.07
107	Charge syndrome	Enrichment	EP300, KMT2D	2.05
108	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	SETD1A, TNRC6B	2.05
109	Familial colorectal cancer type x	Enrichment	POLD1, POLE	2.03
110	Lactose intolerance, adult type	Enrichment	MCM6	2.01
111	Meier-gorlin syndrome 3	Enrichment	ORC6	2.01
112	Meier-gorlin syndrome 2	Enrichment	ORC4	2.01
113	Meier-gorlin syndrome 4	Enrichment	CDT1	2.01
114	Anisometropia	Enrichment	MCM7	2.01
115	Ferguson-bonni neurodevelopmental syndrome	Enrichment	ANAPC7	2.01
116	Developmental and epileptic encephalopathy 109	Enrichment	FZR1	2.01
117	Immunodeficiency 54	Enrichment	MCM4	2.01
118	Deafness, autosomal dominant 70	Enrichment	MCM2	2.01
119	Meier-gorlin syndrome 8	Enrichment	MCM5	2.01
120	Rothmund-thomson syndrome, type 1	Enrichment	ANAPC1	2.01
121	Premature ovarian failure 10	Enrichment	MCM8	2.01
122	Meier-gorlin syndrome 5	Enrichment	CDC6	2.01
123	Meier-gorlin syndrome 6	Enrichment	GMNN	2.01
124	Autosomal dominant macrothrombocytopenia	Enrichment	GP1BA, ITGA2B	1.96
125	Cystic fibrosis with helicobacter pylori gastritis, megaloblastic anemia, and impaired intellectual development	Enrichment	POLE	1.96
126	Van esch-o'driscoll syndrome	Enrichment	POLA1	1.96
127	Colorectal cancer 12	Enrichment	POLE	1.96
128	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 6	Enrichment	RPA1	1.96
129	Immunodeficiency 80 with or without congenital cardiomyopathy	Enrichment	MCM10	1.96
130	Pigmentary disorder, reticulate, with systemic manifestations, x-linked	Enrichment	POLA1	1.96
131	Meier-gorlin syndrome 7	Enrichment	CDC45	1.96
132	Perrault syndrome 1	Enrichment	TWNK	1.93
133	Meningioma, familial	Enrichment	SMARCB1, SMARCE1	1.88
134	Atrial heart septal defect	Enrichment	ACTL6A, SMARCA4	1.88
135	Interatrial communication	Enrichment	ACTL6A, SMARCA4	1.88
136	Specific learning disability	Enrichment	KMT2B, PTPN11	1.88
137	Colorectal cancer 10	Enrichment	POLD1	1.87
138	Seckel syndrome 8	Enrichment	DNA2	1.87
139	Immunodeficiency 120	Enrichment	POLD1	1.87
140	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 6	Enrichment	DNA2	1.87
141	Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome	Enrichment	POLD1	1.87
142	Ataxia-telangiectasia-like disorder 2	Enrichment	PCNA	1.87
143	Immunodeficiency 96	Enrichment	LIG1	1.87
144	Rothmund-thomson syndrome, type 4	Enrichment	DNA2	1.87
145	Morimoto-ryu-malicdan neuromuscular syndrome	Enrichment	RFC4	1.87
146	Immunodeficiency 122	Enrichment	POLD3	1.87
147	Seckel syndrome	Enrichment	DNA2, PRIM1	1.83
148	Meningioma	Enrichment	SMARCB1, SMARCE1	1.81
149	Bernard-soulier syndrome, type a2, autosomal dominant	Enrichment	GP1BA	1.79
150	Metachondromatosis	Enrichment	PTPN11	1.79
151	Torticollis	Enrichment	ACTL6A	1.79
152	Type 1 diabetes mellitus 10	Enrichment	IL2RA	1.79
153	Immunodysregulation, polyendocrinopathy, and enteropathy, x-linked	Enrichment	FOXP3	1.79
154	Nonarteritic anterior ischemic optic neuropathy	Enrichment	GP1BA	1.79
155	Pycnodysostosis	Enrichment	CTSK	1.79
156	46,xy sex reversal 5	Enrichment	CBX2	1.79
157	Branchial cleft anomalies	Enrichment	KMT2D	1.79
158	Von willebrand disease, platelet-type	Enrichment	GP1BA	1.79
159	Celiac disease 3	Enrichment	CTLA4	1.79
160	Dermatitis, atopic, 4	Enrichment	SOCS3	1.79
161	Leopard syndrome 1	Enrichment	PTPN11	1.79
162	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3	Enrichment	CCND2	1.79
163	Microcephaly 12, primary, autosomal recessive	Enrichment	CDK6	1.79
164	Coffin-siris syndrome 5	Enrichment	SMARCE1	1.79
165	Caudal duplication anomaly	Enrichment	AXIN1	1.79
166	Microcephaly 11, primary, autosomal recessive	Enrichment	PHC1	1.79
167	Intellectual developmental disorder with severe speech and ambulation defects	Enrichment	ACTL6B	1.79
168	Global developmental delay with speech and behavioral abnormalities	Enrichment	TNRC6B	1.79
169	Luo-schoch-yamamoto syndrome	Enrichment	RNF2	1.79
170	Coffin-siris syndrome 11	Enrichment	SMARCD1	1.79
171	Immunodeficiency 69	Enrichment	IFNG	1.79
172	Neurodevelopmental disorder with speech impairment and dysmorphic facies	Enrichment	SETD1A	1.79
173	Hydrocephalus, congenital, 5	Enrichment	SMARCC1	1.79
174	Fetomaternal alloimmune thrombocytopenia 2	Enrichment	ITGA2B	1.79
175	Type 1 diabetes mellitus 12	Enrichment	CTLA4	1.79
176	Rhabdoid tumor predisposition syndrome 1	Enrichment	SMARCB1	1.79
177	Epilepsy, early-onset, 2, with or without developmental delay	Enrichment	SETD1A	1.79
178	Intellectual developmental disorder with seizures and language delay	Enrichment	SETD1B	1.79
179	Neurilemmoma	Enrichment	SMARCB1	1.79
180	Branchial arch abnormalities, choanal atresia, athelia, hearing loss, and hypothyroidism syndrome	Enrichment	KMT2D	1.79
181	Coffin-siris syndrome 3	Enrichment	SMARCB1	1.79
182	Kleefstra syndrome 2	Enrichment	KMT2C	1.79
183	Smarca4-deficient sarcoma of thorax	Enrichment	SMARCA4	1.79
184	Arid1b-related disorder	Enrichment	ARID1B	1.79
185	Ovarian small cell carcinoma	Enrichment	SMARCA4	1.79
186	Epilepsy, familial adult myoclonic, 6	Enrichment	TNRC6A	1.79
187	Thrombocytopenia 6	Enrichment	SRC	1.79
188	Okur-chung neurodevelopmental syndrome	Enrichment	CSNK2A1	1.79
189	Intellectual developmental disorder, autosomal dominant 68	Enrichment	KMT2B	1.79
190	Blepharophimosis-impaired intellectual development syndrome	Enrichment	SMARCA2	1.79
191	Menke-hennekam syndrome 1	Enrichment	CREBBP	1.79
192	Generalized isolated dystonia	Enrichment	KMT2B	1.79
193	Craniometadiaphyseal osteosclerosis with hip dysplasia	Enrichment	AXIN1	1.79
194	Kmt2b-related disorders	Enrichment	KMT2B	1.79
195	Bernard-soulier syndrome type a2	Enrichment	GP1BA	1.79
196	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	1.79
197	Craniodigital syndrome and intellectual disability syndrome	Enrichment	CSNK2B	1.79
198	Chromosome 15q24 deletion syndrome	Enrichment	SIN3A	1.79
199	Facial cleft	Enrichment	SMARCE1	1.79
200	Autosomal recessive severe congenital neutropenia	Enrichment	SMARCD2	1.79
201	Menke-hennekam syndrome	Enrichment	CREBBP	1.79
202	Multiple congenital anomalies/dysmorphic syndrome-intellectual disability	Enrichment	AUTS2	1.79
203	Malignant astrocytoma	Enrichment	PTPN11	1.79
204	Myeloproliferative syndrome, transient	Enrichment	GATA1	1.77
205	Hypoparathyroidism, sensorineural deafness, and renal dysplasia syndrome	Enrichment	GATA3	1.77
206	Storage pool platelet disease	Enrichment	RUNX1	1.77
207	Porphyria, congenital erythropoietic	Enrichment	GATA1	1.77
208	Congenital heart defects and skeletal malformations syndrome	Enrichment	ABL1	1.77
209	Birk-aharoni syndrome	Enrichment	PSMC1	1.77
210	Proteasome-associated autoinflammatory syndrome 3	Enrichment	PSMB4	1.77
211	Cleidocranial dysplasia 2	Enrichment	CBFB	1.77
212	Neuroblastoma 7	Enrichment	LMO1	1.77
213	Angiocentric glioma	Enrichment	MYB	1.77
214	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	GATA3	1.77
215	Hypoparathyroidism-deafness-renal disease syndrome	Enrichment	GATA3	1.77
216	17q24.2 microdeletion syndrome	Enrichment	PSMD12	1.77
217	B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3)	Enrichment	TCF3	1.77
218	Autosomal dominant nonsyndromic deafness	Enrichment	GATA3	1.77
219	Acute myeloid leukemia with t(9;11)(p22;q23)	Enrichment	KMT2A	1.77
220	Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2)	Enrichment	KMT2A	1.77
221	B-lymphoblastic leukemia/lymphoma with t	Enrichment	KMT2A	1.77
222	B-lymphoblastic leukemia/lymphoma with t(17;19)	Enrichment	TCF3	1.77
223	Tafro syndrome	Enrichment	RUNX1	1.77
224	Submucosal cleft palate	Enrichment	UBB	1.77
225	Cleft hard palate	Enrichment	UBB	1.77
226	Heart disease	Enrichment	ABL1, CREBBP	1.67
227	Intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies	Enrichment	POLE	1.66
228	Intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, genital anomalies, and immunodeficiency	Enrichment	POLE	1.66
229	Primordial dwarfism-immunodeficiency-lipodystrophy syndrome	Enrichment	PRIM1	1.66
230	Facial dysmorphism, immunodeficiency, livedo, and short stature	Enrichment	POLE	1.66
231	Proteasome-associated autoinflammatory syndrome 1	Enrichment	PSMB4	1.60
232	Uvula, bifid	Enrichment	UBB	1.60
233	Platelet disorder, familial, with associated myeloid malignancy	Enrichment	RUNX1	1.60
234	Cleft soft palate	Enrichment	UBB	1.60
235	Wieacker-wolff syndrome	Enrichment	CCNH	1.60
236	Proteosome-associated autoinflammatory syndrome	Enrichment	PSMB4	1.60
237	T-cell acute lymphoblastic leukemia	Enrichment	ABL1	1.60
238	End stage renal disease	Enrichment	GATA3	1.60
239	Adenoid cystic carcinoma	Enrichment	MYB	1.60
240	Mixed phenotype acute leukemia with t	Enrichment	KMT2A	1.60
241	Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with runx1	Enrichment	RUNX1	1.60
242	Thyroid hemiagenesis	Enrichment	PSMD3	1.60
243	Rothmund-thomson syndrome, type 2	Enrichment	DNA2	1.57
244	Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome	Enrichment	RFC1	1.57
245	Immunodeficiency 55	Enrichment	GINS1	1.57
246	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	Enrichment	POLG	1.56
247	Autism	Enrichment	ACTL6B, CREBBP, KMT2B, KMT2D	1.53
248	Hereditary spastic paraplegia	Enrichment	POLG	1.52
249	Hypertrophic cardiomyopathy	Enrichment	POLG	1.50
250	Hashimoto thyroiditis	Enrichment	CTLA4	1.49
251	Metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly	Enrichment	RUNX2	1.49
252	Alopecia, androgenetic, 1	Enrichment	SMARCD1	1.49
253	Multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly	Enrichment	FOXP3	1.49
254	Trichomegaly	Enrichment	ARID1B	1.49
255	Specific granule deficiency 1	Enrichment	SMARCD2	1.49
256	Thumb deformity	Enrichment	CREBBP	1.49
257	Immunodeficiency 41 with lymphoproliferation and autoimmunity	Enrichment	IL2RA	1.49
258	Rhabdoid tumor predisposition syndrome 2	Enrichment	SMARCA4	1.49
259	Premature ovarian failure 3	Enrichment	AGO2	1.49
260	Schwannomatosis 1	Enrichment	SMARCB1	1.49
261	Complement component c1s deficiency	Enrichment	KMT2D	1.49
262	Chromosome 6q24-q25 deletion syndrome	Enrichment	ARID1B	1.49
263	Maturity-onset diabetes of the young, type 11	Enrichment	BLK	1.49
264	Choanal atresia, posterior	Enrichment	KMT2D	1.49
265	Severe combined immunodeficiency with sensitivity to ionizing radiation	Enrichment	ARID1B	1.49
266	Coffin-siris syndrome 6	Enrichment	ARID2	1.49
267	Specific granule deficiency 2	Enrichment	SMARCD2	1.49
268	Coffin-siris syndrome 8	Enrichment	SMARCC2	1.49
269	Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures	Enrichment	AGO1	1.49
270	Werner syndrome	Enrichment	PTPN11	1.49
271	Poirier-bienvenu neurodevelopmental syndrome	Enrichment	CSNK2B	1.49
272	Menke-hennekam syndrome 2	Enrichment	EP300	1.49
273	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.49
274	Kleefstra syndrome	Enrichment	KMT2C	1.49
275	Otosclerosis 12	Enrichment	SMARCA4	1.49
276	Coffin-siris syndrome 4	Enrichment	SMARCA4	1.49
277	Blepharophimosis - intellectual disability syndrome	Enrichment	SMARCA2	1.49
278	Dystonia 28, childhood-onset	Enrichment	KMT2B	1.49
279	Megacystis-microcolon-intestinal hypoperistalsis syndrome 4	Enrichment	MYL9	1.49
280	Developmental and epileptic encephalopathy 76	Enrichment	ACTL6B	1.49
281	Joint contractures, osteochondromas, and b-cell lymphoma	Enrichment	NFATC2	1.49
282	Kleefstra syndrome due to a point mutation	Enrichment	KMT2C	1.49
283	Specific granule deficiency	Enrichment	SMARCD2	1.49
284	Partington syndrome	Enrichment	POLA1	1.49
285	Down syndrome	Enrichment	GATA1	1.48
286	Malignant epithelioid hemangioendothelioma	Enrichment	YAP1	1.48
287	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	ABL1	1.48
288	Blood platelet disease	Enrichment	RUNX1	1.48
289	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	CBFB	1.48
290	Non-syndromic bicoronal craniosynostosis	Enrichment	TCF12	1.48
291	Patent foramen ovale	Enrichment	PSMC3, PTPN11	1.47
292	Body mass index quantitative trait locus 11	Enrichment	POLG	1.44
293	Astigmatism	Enrichment	MCM7	1.42
294	Enophthalmos	Enrichment	MCM7	1.42
295	Childhood apraxia of speech	Enrichment	RFC3	1.40
296	Capillary malformations, congenital	Enrichment	CCNH	1.38
297	Aggressive systemic mastocytosis	Enrichment	RUNX1	1.38
298	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	RUNX1	1.38
299	Primary ovarian insufficiency	Enrichment	POLG	1.37
300	Deafness, autosomal recessive 63	Enrichment	ANAPC15	1.32
301	2q23.1 microduplication syndrome	Enrichment	ORC4	1.32
302	Farsightedness	Enrichment	MCM7	1.32
303	Cleidocranial dysplasia 1	Enrichment	RUNX2	1.32
304	Dystonia 12	Enrichment	KMT2B	1.32
305	Prognathism, mandibular	Enrichment	CSNK2B	1.32
306	Bleeding disorder, platelet-type, 16	Enrichment	ITGA2B	1.32
307	Mycosis fungoides	Enrichment	CTLA4	1.32
308	Tuberous sclerosis 1	Enrichment	IFNG	1.32
309	Stuve-wiedemann syndrome 1	Enrichment	LIFR	1.32
310	Hepatitis c virus	Enrichment	IFNG	1.32
311	Estrogen resistance	Enrichment	ESR1	1.32
312	Tuberous sclerosis 2	Enrichment	IFNG	1.32
313	Immune dysregulation with autoimmunity, immunodeficiency, and lymphoproliferation	Enrichment	CTLA4	1.32
314	Intellectual developmental disorder, autosomal dominant 57	Enrichment	AUTS2	1.32
315	Tethered spinal cord syndrome	Enrichment	CREBBP	1.32
316	Coffin-siris syndrome 2	Enrichment	ARID1A	1.32
317	Umbilical hernia	Enrichment	ACTL6A	1.32
318	Asparagine synthetase deficiency	Enrichment	CTLA4	1.32
319	Atypical teratoid rhabdoid tumor	Enrichment	SMARCB1	1.32
320	Cleidocranial dysplasia	Enrichment	RUNX2	1.32
321	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.32
322	Migraine without aura	Enrichment	ESR1	1.32
323	Periventricular leukomalacia	Enrichment	ARID1A	1.32
324	Desmoplastic/nodular medulloblastoma	Enrichment	ARID2	1.32
325	Schwannomatosis	Enrichment	SMARCB1	1.32
326	Lessel-kreienkamp syndrome	Enrichment	AGO2	1.32
327	Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome	Enrichment	CTLA4	1.32
328	Adult-onset myasthenia gravis	Enrichment	CTLA4	1.32
329	Tricuspid valve insufficiency	Enrichment	PTPN11	1.32
330	Stüve-wiedemann syndrome	Enrichment	LIFR	1.32
331	Saczary syndrome	Enrichment	CTLA4	1.32
332	Cone-rod dystrophy 2	Enrichment	SSBP1	1.31
333	Myocardial infarction	Enrichment	ESR1, PSMA6	1.31
334	Leigh syndrome, nuclear	Enrichment	POLG	1.30
335	Developmental dysplasia of the hip 1	Enrichment	PSMC3	1.30
336	Klippel-trenaunay-weber syndrome	Enrichment	CCNH	1.30
337	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	CCNH	1.30
338	Hemangioma, capillary infantile	Enrichment	CCNH	1.30
339	Basal cell carcinoma 1	Enrichment	CCNH	1.30
340	Pancytopenia	Enrichment	RUNX1	1.30
341	Colorectal cancer	Enrichment	ARID1A, CCND1, EP300, SRC	1.27
342	Capillary malformation-arteriovenous malformation 1	Enrichment	CCNH	1.24
343	Hereditary hemorrhagic telangiectasia	Enrichment	CCNH	1.24
344	Moyamoya angiopathy	Enrichment	ABL1	1.24
345	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	ABL1	1.24
346	Microtia-anotia	Enrichment	KMT2D	1.20
347	Lipodystrophy, congenital generalized, type 2	Enrichment	ACTL6B	1.20
348	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	CCND2	1.20
349	Immunodeficiency, common variable, 1	Enrichment	CTLA4	1.20
350	Mantle cell lymphoma	Enrichment	CCND1	1.20
351	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	1.20
352	Syndactyly	Enrichment	CSNK2B	1.20
353	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	PTPN11	1.20
354	Noonan syndrome with multiple lentigines	Enrichment	PTPN11	1.20
355	Full schwannomatosis	Enrichment	SMARCB1	1.20
356	Clear cell papillary renal cell carcinoma	Enrichment	PBRM1	1.20
357	Inherited cancer-predisposing syndrome	Enrichment	PTPN11, RUNX1, SMARCA4, SMARCB1, SMARCE1	1.19
358	Isolated split hand-split foot malformation	Enrichment	SEM1	1.18
359	Hydrops fetalis, nonimmune	Enrichment	ARID1A, PTPN11	1.18
360	Strabismus	Enrichment	KMT2D, PTPN11	1.15
361	Cornelia de lange syndrome 1	Enrichment	KMT2A	1.13
362	Arteriovenous malformation	Enrichment	CCNH	1.13
363	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	RUNX1	1.13
364	Cornelia de lange syndrome	Enrichment	KMT2A	1.13
365	Congenital nervous system abnormality	Enrichment	POLG	1.12
366	Nervous system disease	Enrichment	POLG	1.12
367	Bernard-soulier syndrome	Enrichment	GP1BA	1.10
368	Von hippel-lindau syndrome	Enrichment	CCND1	1.10
369	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.10
370	Amblyopia	Enrichment	KMT2D	1.10
371	Idiopathic aplastic anemia	Enrichment	IFNG	1.10
372	Myopathy, x-linked, with excessive autophagy	Enrichment	CCNH	1.09
373	Polymicrogyria	Enrichment	PSMC3	1.09
374	Myelodysplastic syndrome	Enrichment	GATA2	1.05
375	Non-immune hydrops fetalis	Enrichment	ARID1A, PTPN11	1.04
376	Type 1 diabetes mellitus	Enrichment	FOXP3	1.03
377	Kleefstra syndrome 1	Enrichment	KMT2C	1.03
378	Granulomatosis with polyangiitis	Enrichment	CTLA4	1.03
379	Inguinal hernia	Enrichment	ACTL6A	1.03
380	Clear cell renal cell carcinoma	Enrichment	PBRM1	1.03
381	Primary autosomal recessive microcephaly	Enrichment	CDK6, PHC1	1.02
382	Lip and oral cavity carcinoma	Enrichment	ABL1	1.01
383	Isolated growth hormone deficiency, type ia	Enrichment	DNA2	0.98
384	Microphthalmia/coloboma 12	Enrichment	YAP1	0.98
385	Protein-deficiency anemia	Enrichment	GATA1	0.98
386	Cakut	Enrichment	GATA3, LIFR	0.98
387	Myelofibrosis	Enrichment	SRC	0.96
388	Glanzmann thrombasthenia 1	Enrichment	ITGA2B	0.96
389	Noonan syndrome 3	Enrichment	PTPN11	0.96
390	Oligoarticular juvenile idiopathic arthritis	Enrichment	IL2RA	0.96
391	Congenital hydrocephalus	Enrichment	SMARCC1	0.96
392	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	IL2RA	0.96
393	Coloboma of macula	Enrichment	YAP1	0.92
394	Gastroesophageal reflux	Enrichment	ACTL6A	0.91
395	Systemic lupus erythematosus	Enrichment	BLK, CTLA4	0.88
396	Leukemia, acute lymphoblastic 3	Enrichment	PAX5	0.86
397	Adult hepatocellular carcinoma	Enrichment	AXIN1	0.86
398	Ventricular septal defect	Enrichment	SMARCA4	0.86
399	Hydrops fetalis	Enrichment	FOXP3	0.86
400	Combined immunodeficiency	Enrichment	POLD1	0.86
401	Combined t cell and b cell immunodeficiency	Enrichment	POLD1	0.86
402	Combined t and b cell immunodeficiency	Enrichment	POLD1	0.86
403	Leukemia, chronic lymphocytic	Enrichment	CCND1	0.82
404	Aplastic anemia	Enrichment	IFNG	0.82
405	Primary bone dysplasia	Enrichment	CTSK	0.82
406	Craniosynostosis	Enrichment	TCF12	0.81
407	Migraine with or without aura 1	Enrichment	ESR1	0.78
408	Pectus excavatum	Enrichment	PTPN11	0.78
409	Leukemia, acute lymphoblastic	Enrichment	PAX5	0.78
410	46,xy complete gonadal dysgenesis	Enrichment	CBX2	0.78
411	Osteochondrodysplasia	Enrichment	CTSK	0.78
412	Azoospermia	Enrichment	MCM8	0.75
413	Diamond-blackfan anemia 1	Enrichment	GATA1	0.75
414	Epicanthus	Enrichment	PTPN11	0.75
415	Septooptic dysplasia	Enrichment	ARID1A	0.75
416	Juvenile myelomonocytic leukemia	Enrichment	PTPN11	0.75
417	Congenital long qt syndrome	Enrichment	PTPN11	0.75
418	Hypercholesterolemia, familial, 1	Enrichment	SMARCA4	0.72
419	Acute promyelocytic leukemia	Enrichment	PML	0.72
420	Nk-cell enteropathy	Enrichment	SMARCB1	0.72
421	Microphthalmia	Enrichment	MCM7	0.71
422	Autosomal dominant non-syndromic intellectual disability	Enrichment	CSNK2B, SETD1B	0.71
423	Osteoporosis	Enrichment	SRC	0.69
424	Pituitary stalk interruption syndrome	Enrichment	SMARCA2	0.69
425	Renal cell carcinoma, nonpapillary	Enrichment	PBRM1	0.66
426	Polydactyly, postaxial, type a1	Enrichment	EP300	0.66
427	Familial hypercholesterolemia	Enrichment	SMARCA4	0.66
428	Male infertility with spermatogenesis disorder	Enrichment	KMT2D	0.66
429	Noonan syndrome and noonan-related syndrome	Enrichment	PTPN11	0.66
430	Parkinson's disease	Enrichment	RFC1	0.64
431	Isolated congenital microcephaly	Enrichment	PHC1	0.64
432	Williams-beuren syndrome	Enrichment	RFC2	0.62
433	Cleft palate, isolated	Enrichment	SMARCA4	0.61
434	Dandy-walker syndrome	Enrichment	KMT2D	0.61
435	Human immunodeficiency virus type 1	Enrichment	IFNG	0.59
436	Diamond-blackfan anemia	Enrichment	GATA1	0.58
437	Diffuse large b-cell lymphoma	Enrichment	CREBBP	0.57
438	Parkinson disease, late-onset	Enrichment	RFC1	0.55
439	Maturity-onset diabetes of the young	Enrichment	BLK	0.55
440	Pancreatic cancer	Enrichment	POLD1	0.54
441	Cardiomyopathy, dilated, 1a	Enrichment	NFATC2	0.53
442	Centronuclear myopathy	Enrichment	FOXP3	0.53
443	Hepatocellular carcinoma	Enrichment	AXIN1	0.52
444	Noonan syndrome 1	Enrichment	PTPN11	0.50
445	Malaria	Enrichment	CR1	0.50
446	Breast cancer	Enrichment	ESR1, IL2	0.46
447	Rasopathy	Enrichment	PTPN11	0.46
448	Bladder cancer	Enrichment	ARID1A	0.42
449	Long qt syndrome 1	Enrichment	PTPN11	0.41
450	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	MCM2	0.40
451	Lung cancer	Enrichment	KMT2D	0.39
452	Undetermined early-onset epileptic encephalopathy	Enrichment	FZR1	0.37
453	Dystonia	Enrichment	KMT2B	0.36
454	Cerebral palsy	Enrichment	SMARCA4	0.32
455	Epilepsy	Enrichment	SETD1B	0.32
456	Nephrotic syndrome	Enrichment	RUNX2	0.29
457	Hereditary breast carcinoma	Enrichment	ESR1	0.29
458	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	PTPN11	0.22
459	Schizophrenia	Enrichment	SETD1A	0.21
460	Ovarian cancer	Enrichment	SMARCB1	0.09

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

DNA Replication

Pathway Network for DNA Replication

Pathway network for the DNA Replication SuperPath

Member Pathways for DNA Replication

Pathways in the DNA Replication SuperPath

Gene overlap in member pathways for DNA Replication SuperPath

Associated Genes for DNA Replication

Associated Disorders for DNA Replication

Disorders associated with DNA Replication SuperPath

STRING Interaction Network for DNA Replication

Sources for DNA Replication