dopamine degradation
Pathways in the dopamine degradation SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | dopamine degradation | PubChem |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | ALDH3A2 | Aldehyde Dehydrogenase 3 Family Member A2 | Protein Coding | 1 |
| 2 | SULT1A3 | Sulfotransferase Family 1A Member 3 | Protein Coding | 1 |
| 3 | SULT1A4 | Sulfotransferase Family 1A Member 4 | Protein Coding | 1 |
| 4 | MAOA | Monoamine Oxidase A | Protein Coding | 1 |
| 5 | COMT | Catechol-O-Methyltransferase | Protein Coding | 1 |
Disorders associated with dopamine degradation SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Brunner syndrome | Enrichment | MAOA | 3.43 |
| 2 | Catechol-o-methyltransferase activity, variation in | Enrichment | COMT | 3.43 |
| 3 | Sjogren-larsson syndrome | Enrichment | ALDH3A2 | 3.13 |
| 4 | Digeorge syndrome | Enrichment | COMT | 2.35 |
| 5 | Cerebral palsy | Enrichment | ALDH3A2 | 1.84 |
| 6 | Bardet-biedl syndrome | Enrichment | COMT | 1.81 |
| 7 | Schizophrenia | Enrichment | COMT | 1.67 |
