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Downstream signaling of activated FGFR2
SuperPath
Pathway network
for
Downstream signaling of activated FGFR2
SuperPath
39
Pathways
in the
Downstream signaling of activated FGFR2
SuperPath
Activated NTRK2 signals through PLCG1
Downstream signaling of activated FGFR4
betaKlotho-mediated ligand binding
Downstream signaling of activated FGFR1
SHC-mediated cascade:FGFR1
BDNF activates NTRK2 (TRKB) signaling
FRS-mediated FGFR4 signaling
FGFR4 ligand binding and activation
FRS-mediated FGFR2 signaling
FGFR2c ligand binding and activation
Signaling by FGFR3 in disease
FRS-mediated FGFR1 signaling
SHC-mediated cascade:FGFR2
Signaling by FGFR4 in disease
Activated NTRK2 signals through CDK5
Signaling by NTRK2 (TRKB)
Activated NTRK2 signals through PI3K
Phospholipase C-mediated cascade: FGFR1
Phospholipase C-mediated cascade; FGFR2
Phospholipase C-mediated cascade; FGFR4
PI-3K cascade:FGFR3
Activated point mutants of FGFR2
NTRK2 activates RAC1
Inhibition of Ribosome Biogenesis by p19(ARF)
Downstream signaling of activated FGFR2
Phospholipase C-mediated cascade; FGFR3
NTF3 activates NTRK2 (TRKB) signaling
PI-3K cascade:FGFR4
NTF4 activates NTRK2 (TRKB) signaling
Activated NTRK2 signals through FYN
Activated NTRK2 signals through RAS
Activated NTRK2 signals through FRS2 and FRS3
FRS-mediated FGFR3 signaling
PI-3K cascade:FGFR2
FGFR4 mutant receptor activation
PI-3K cascade:FGFR1
SHC-mediated cascade:FGFR3
Downstream signaling of activated FGFR3
SHC-mediated cascade:FGFR4
51
Genes
in the
Downstream signaling of activated FGFR2
SuperPath
FGF1
FGF2
FGF4
FGF8
FGF9
FGF20
FGF23
FGF17
GRB2
FGF18
FGF16
FGF6
FGF5
HRAS
KRAS
NRAS
SOS1
FRS2
PTPN11
PLCG1
GAB1
PIK3CA
PIK3R1
NTRK2
FGF3
FGF10
FGF22
FRS3
SHC1
BDNF
FGFR4
KLB
FGF19
FGFR2
NTF4
FGF7
FGFR3
FGFR1
KL
RAC1
DOCK3
FYN
CDK5
TIAM1
CDK5R1
GRIN2B
NTF3
SRC
FLRT3
FLRT2
FLRT1
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
Downstream signaling of activated FGFR2
SuperPath