Dual hijack model of Vif in HIV infection
Pathways in the Dual hijack model of Vif in HIV infection SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Dual hijack model of Vif in HIV infection | WikiPathways | |
| 2 | Hijack of ubiquitination by SARS-CoV-2 | WikiPathways |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | RBX1 | Ring-Box 1 | Protein Coding | 2 |
| 2 | CBFB | Core-Binding Factor Subunit Beta | Protein Coding | 2 |
| 3 | ELOC | Elongin C | Protein Coding | 2 |
| 4 | ELOB | Elongin B | Protein Coding | 2 |
| 5 | APOBEC3G | Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 3G | Protein Coding | 1 |
| 6 | CUL5 | Cullin 5 | Protein Coding | 1 |
| 7 | UBB | Ubiquitin B | Protein Coding | 1 |
| 8 | LOC100506403 | Uncharacterized LOC100506403 | RNA Gene | 1 |
| 9 | CUL2 | Cullin 2 | Protein Coding | 1 |
| 10 | UBA3 | Ubiquitin Like Modifier Activating Enzyme 3 | Protein Coding | 1 |
| 11 | NAE1 | NEDD8 Activating Enzyme E1 Subunit 1 | Protein Coding | 1 |
| 12 | ZYG11B | Zyg-11 Family Member B, Cell Cycle Regulator | Protein Coding | 1 |
Disorders associated with Dual hijack model of Vif in HIV infection SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Neurodevelopmental disorder with dysmorphic facies and ischiopubic hypoplasia | Enrichment | NAE1 | 3.23 |
| 2 | Cleidocranial dysplasia 2 | Enrichment | CBFB | 2.93 |
| 3 | Submucosal cleft palate | Enrichment | UBB | 2.93 |
| 4 | Cleft hard palate | Enrichment | UBB | 2.93 |
| 5 | Uvula, bifid | Enrichment | UBB | 2.75 |
| 6 | Cleft soft palate | Enrichment | UBB | 2.75 |
| 7 | Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) | Enrichment | CBFB | 2.63 |
| 8 | Craniofacial microsomia 1 | Enrichment | ZYG11B | 2.45 |