Ebola virus infection in host

No Pathway Network information available for Ebola virus infection in host

Pathways in the Ebola virus infection in host SuperPath

#	Name	Source	Genes
1	Ebola virus infection in host	WikiPathways	ACTB ACTG1 ACTN1 ACTN4 ADAM17 AKT1 ASGR1 AXL BST2 C1QBP CAV1 CAV2 CAV3 CD209 CD300A CDC42 CLEC10A CLEC4G CLEC4M CLEC6A CLTA CLTB CLTC CLTCL1 CREBBP CTSB CTSL DAB2IP EGFR EIF2AK2 EIF2S1 EP300 EPS15 FLNA FLNB FLNC FOLR1 GAS6 GSN HAVCR1 HAVCR2 HLA-A HLA-B HLA-C HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-E HLA-F HLA-G ICAM2 ICAM3 IGF1R IKBKE IL4 IQGAP1 IRF3 IRF7 ITGA1 ITGA2 ITGA3 ITGA4 ITGA5 ITGA6 ITGAV ITGB1 ITGB3 KPNA1 MAPK1 MBL2 MERTK MFGE8 NEDD4 NFKB1 NFKB2 NPC1 NPC2 PAK1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PRKRA RAB5A RAB7A RAB9A RAC1 RASA2 REL RELA RELB RHOA RHOB RHOC RIGI SCIN SOCS3 STAT1 TBK1 TFAP2A TIAM1 TIMD4 TLR4 TOP1 TPCN2 TSG101 TYRO3 VAV2 VPS11 VPS16 VPS18 VPS33A VPS39 VPS41 VPS4A (see all 129) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CLEC6A	C-Type Lectin Domain Containing 6A	Protein Coding	1
2	BST2	Bone Marrow Stromal Cell Antigen 2	Protein Coding	1
3	ASGR1	Asialoglycoprotein Receptor 1	Protein Coding	1
4	VPS4A	Vacuolar Protein Sorting 4 Homolog A	Protein Coding	1
5	CDC42	Cell Division Cycle 42	Protein Coding	1
6	TIMD4	T Cell Immunoglobulin And Mucin Domain Containing 4	Protein Coding	1
7	SOCS3	Suppressor Of Cytokine Signaling 3	Protein Coding	1
8	IQGAP1	IQ Motif Containing GTPase Activating Protein 1	Protein Coding	1
9	ACTN1	Actinin Alpha 1	Protein Coding	1
10	CAV3	Caveolin 3	Protein Coding	1
11	CAV2	Caveolin 2	Protein Coding	1
12	PRKRA	Protein Activator Of Interferon Induced Protein Kinase EIF2AK2	Protein Coding	1
13	CAV1	Caveolin 1	Protein Coding	1
14	HAVCR2	Hepatitis A Virus Cellular Receptor 2	Protein Coding	1
15	ACTN4	Actinin Alpha 4	Protein Coding	1
16	RAB7A	RAB7A, Member RAS Oncogene Family	Protein Coding	1
17	TYRO3	TYRO3 Protein Tyrosine Kinase	Protein Coding	1
18	TOP1	DNA Topoisomerase I	Protein Coding	1
19	ACTG1	Actin Gamma 1	Protein Coding	1
20	TLR4	Toll Like Receptor 4	Protein Coding	1
21	C1QBP	Complement C1q Binding Protein	Protein Coding	1
22	TIAM1	TIAM Rac1 Associated GEF 1	Protein Coding	1
23	TFAP2A	Transcription Factor AP-2 Alpha	Protein Coding	1
24	ADAM17	ADAM Metallopeptidase Domain 17	Protein Coding	1
25	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	1
26	VPS33A	VPS33A Core Subunit Of CORVET And HOPS Complexes	Protein Coding	1
27	ACTB	Actin Beta	Protein Coding	1
28	RELB	RELB Proto-Oncogene, NF-KB Subunit	Protein Coding	1
29	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	1
30	REL	REL Proto-Oncogene, NF-KB Subunit	Protein Coding	1
31	RASA2	RAS P21 Protein Activator 2	Protein Coding	1
32	RAC1	Rac Family Small GTPase 1	Protein Coding	1
33	RAB5A	RAB5A, Member RAS Oncogene Family	Protein Coding	1
34	EIF2AK2	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2	Protein Coding	1
35	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
36	VPS11	VPS11 Core Subunit Of CORVET And HOPS Complexes	Protein Coding	1
37	AXL	AXL Receptor Tyrosine Kinase	Protein Coding	1
38	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	1
39	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
40	PIK3CD	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta	Protein Coding	1
41	PIK3CB	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta	Protein Coding	1
42	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
43	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	1
44	NPC1	NPC Intracellular Cholesterol Transporter 1	Protein Coding	1
45	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
46	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
47	NEDD4	NEDD4 E3 Ubiquitin Protein Ligase	Protein Coding	1
48	MFGE8	Milk Fat Globule EGF And Factor V/VIII Domain Containing	Protein Coding	1
49	MBL2	Mannose Binding Lectin 2	Protein Coding	1
50	RHOC	Ras Homolog Family Member C	Protein Coding	1
51	RHOB	Ras Homolog Family Member B	Protein Coding	1
52	RHOA	Ras Homolog Family Member A	Protein Coding	1
53	KPNA1	Karyopherin Subunit Alpha 1	Protein Coding	1
54	ITGB3	Integrin Subunit Beta 3	Protein Coding	1
55	ITGB1	Integrin Subunit Beta 1	Protein Coding	1
56	ITGAV	Integrin Subunit Alpha V	Protein Coding	1
57	ITGA5	Integrin Subunit Alpha 5	Protein Coding	1
58	ITGA4	Integrin Subunit Alpha 4	Protein Coding	1
59	ITGA3	Integrin Subunit Alpha 3	Protein Coding	1
60	ITGA2	Integrin Subunit Alpha 2	Protein Coding	1
61	ITGA1	Integrin Subunit Alpha 1	Protein Coding	1
62	IRF7	Interferon Regulatory Factor 7	Protein Coding	1
63	IRF3	Interferon Regulatory Factor 3	Protein Coding	1
64	ITGA6	Integrin Subunit Alpha 6	Protein Coding	1
65	IL4	Interleukin 4	Protein Coding	1
66	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	1
67	CLEC4G	C-Type Lectin Domain Family 4 Member G	Protein Coding	1
68	ICAM3	Intercellular Adhesion Molecule 3	Protein Coding	1
69	ICAM2	Intercellular Adhesion Molecule 2	Protein Coding	1
70	HLA-G	Major Histocompatibility Complex, Class I, G	Protein Coding	1
71	HLA-E	Major Histocompatibility Complex, Class I, E	Protein Coding	1
72	HLA-DRB5	Major Histocompatibility Complex, Class II, DR Beta 5	Protein Coding	1
73	HLA-DRB4	Major Histocompatibility Complex, Class II, DR Beta 4	Protein Coding	1
74	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	Protein Coding	1
75	HLA-DRA	Major Histocompatibility Complex, Class II, DR Alpha	Protein Coding	1
76	HLA-DQB1	Major Histocompatibility Complex, Class II, DQ Beta 1	Protein Coding	1
77	HLA-DQA2	Major Histocompatibility Complex, Class II, DQ Alpha 2	Protein Coding	1
78	HLA-DQA1	Major Histocompatibility Complex, Class II, DQ Alpha 1	Protein Coding	1
79	HLA-DPB1	Major Histocompatibility Complex, Class II, DP Beta 1	Protein Coding	1
80	HLA-DPA1	Major Histocompatibility Complex, Class II, DP Alpha 1	Protein Coding	1
81	HLA-DOA	Major Histocompatibility Complex, Class II, DO Alpha	Protein Coding	1
82	HLA-DMA	Major Histocompatibility Complex, Class II, DM Alpha	Protein Coding	1
83	HLA-C	Major Histocompatibility Complex, Class I, C	Protein Coding	1
84	HLA-B	Major Histocompatibility Complex, Class I, B	Protein Coding	1
85	HLA-A	Major Histocompatibility Complex, Class I, A	Protein Coding	1
86	CD209	CD209 Molecule	Protein Coding	1
87	GSN	Gelsolin	Protein Coding	1
88	TBK1	TANK Binding Kinase 1	Protein Coding	1
89	HAVCR1	Hepatitis A Virus Cellular Receptor 1	Protein Coding	1
90	GAS6	Growth Arrest Specific 6	Protein Coding	1
91	RIGI	RNA Sensor RIG-I	Protein Coding	1
92	FOLR1	Folate Receptor Alpha	Protein Coding	1
93	VPS39	VPS39 Subunit Of HOPS Complex	Protein Coding	1
94	FLNC	Filamin C	Protein Coding	1
95	FLNB	Filamin B	Protein Coding	1
96	FLNA	Filamin A	Protein Coding	1
97	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
98	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
99	EIF2S1	Eukaryotic Translation Initiation Factor 2 Subunit Alpha	Protein Coding	1
100	EGFR	Epidermal Growth Factor Receptor	Protein Coding	1
101	DAB2IP	DAB2 Interacting Protein	Protein Coding	1
102	CTSL	Cathepsin L	Protein Coding	1
103	CTSB	Cathepsin B	Protein Coding	1
104	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
105	CLTC	Clathrin Heavy Chain	Protein Coding	1
106	CLTB	Clathrin Light Chain B	Protein Coding	1
107	NPC2	NPC Intracellular Cholesterol Transporter 2	Protein Coding	1
108	CLEC10A	C-Type Lectin Domain Containing 10A	Protein Coding	1
109	MERTK	MER Proto-Oncogene, Tyrosine Kinase	Protein Coding	1
110	CLEC4M	C-Type Lectin Domain Family 4 Member M	Protein Coding	1
111	SCIN	Scinderin	Protein Coding	1
112	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	1
113	CLTA	Clathrin Light Chain A	Protein Coding	1
114	CD300A	CD300a Molecule	Protein Coding	1
115	CLTCL1	Clathrin Heavy Chain Like 1	Protein Coding	1
116	VAV2	Vav Guanine Nucleotide Exchange Factor 2	Protein Coding	1
117	TSG101	Tumor Susceptibility 101	Protein Coding	1
118	VPS16	VPS16 Core Subunit Of CORVET And HOPS Complexes	Protein Coding	1
119	VPS18	VPS18 Core Subunit Of CORVET And HOPS Complexes	Protein Coding	1
120	IKBKE	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon	Protein Coding	1
121	RAB9A	RAB9A, Member RAS Oncogene Family	Protein Coding	1
122	HLA-F	Major Histocompatibility Complex, Class I, F	Protein Coding	1
123	HLA-DRB3	Major Histocompatibility Complex, Class II, DR Beta 3	Protein Coding	1
124	HLA-DQB2	Major Histocompatibility Complex, Class II, DQ Beta 2	Protein Coding	1
125	HLA-DOB	Major Histocompatibility Complex, Class II, DO Beta	Protein Coding	1
126	HLA-DMB	Major Histocompatibility Complex, Class II, DM Beta	Protein Coding	1
127	VPS41	VPS41 Subunit Of HOPS Complex	Protein Coding	1
128	TPCN2	Two Pore Segment Channel 2	Protein Coding	1
129	EPS15	Epidermal Growth Factor Receptor Pathway Substrate 15	Protein Coding	1

Disorders associated with Ebola virus infection in host SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Celiac disease 1	Enrichment	HLA-DQA1, HLA-DQB1	4.05
2	Niemann-pick disease, type c2	Enrichment	NPC1, NPC2	4.05
3	Severe cutaneous adverse reaction	Enrichment	HLA-A, HLA-B	4.05
4	Bullous pemphigoid	Enrichment	HLA-DQB1, HLA-DRB1	4.05
5	Immune system disease	Enrichment	CDC42, PIK3CD	4.05
6	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	4.05
7	Pediatric multiple sclerosis	Enrichment	HLA-DQB1, HLA-DRB1	4.05
8	Niemann-pick disease type c, severe perinatal form	Enrichment	NPC1, NPC2	4.05
9	Niemann-pick disease type c, severe early infantile neurologic onset	Enrichment	NPC1, NPC2	4.05
10	Niemann-pick disease type c, juvenile neurologic onset	Enrichment	NPC1, NPC2	4.05
11	Niemann-pick disease type c, adult neurologic onset	Enrichment	NPC1, NPC2	4.05
12	Niemann-pick disease type c, late infantile neurologic onset	Enrichment	NPC1, NPC2	4.05
13	Nk-cell enteropathy	Enrichment	AXL, IGF1R, PIK3CB	3.65
14	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	3.57
15	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3CD, PIK3R1	3.57
16	Immunodeficiency 14	Enrichment	PIK3CD, PIK3R1	3.57
17	Neonatal inflammatory skin and bowel disease	Enrichment	ADAM17, EGFR	3.57
18	Temporal arteritis	Enrichment	HLA-B, HLA-DRB1	3.27
19	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA, PIK3R2	3.27
20	Idiopathic achalasia	Enrichment	HLA-DQA1, HLA-DQB1	3.27
21	Niemann-pick disease, type c1	Enrichment	NPC1, NPC2	3.06
22	Narcolepsy 2	Enrichment	HLA-DQB1, HLA-DRB1	3.06
23	Niemann-pick disease	Enrichment	NPC1, NPC2	3.06
24	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1, HLA-DRB1	3.06
25	Microcephaly	Enrichment	ACTB, ACTG1, EP300, IGF1R, MAPK1, NPC2	2.95
26	Cowden syndrome 1	Enrichment	EGFR, PIK3CA	2.88
27	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	2.88
28	Hemihyperplasia, isolated	Enrichment	PIK3CA, RHOA	2.88
29	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	2.88
30	Granulomatosis with polyangiitis	Enrichment	HLA-DPA1, HLA-DPB1	2.88
31	Limited scleroderma	Enrichment	CAV1, HLA-DRB1	2.88
32	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGA2, ITGB3	2.88
33	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA	2.88
34	Lung squamous cell carcinoma	Enrichment	EGFR, PIK3CA	2.88
35	Common variable immunodeficiency	Enrichment	NFKB1, NFKB2	2.74
36	Narcolepsy 1	Enrichment	HLA-DQB1, HLA-DRB1	2.62
37	Severe covid-19	Enrichment	HLA-A, HLA-DQB1, ITGAV	2.59
38	Cowden syndrome	Enrichment	AKT1, PIK3CA	2.51
39	Cat eye syndrome	Enrichment	ACTG1, TFAP2A	2.42
40	Autosomal dominant macrothrombocytopenia	Enrichment	ACTN1, ITGB3	2.42
41	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3CD, PIK3R1	2.42
42	Lung non-small cell carcinoma	Enrichment	EGFR, PIK3CA	2.33
43	Meningioma	Enrichment	AKT1, PIK3CA	2.25
44	Lip and oral cavity carcinoma	Enrichment	EGFR, PIK3CA	2.25
45	Multiple sclerosis	Enrichment	HLA-DQB1, HLA-DRB1	2.12
46	Rare genetic intellectual disability	Enrichment	CREBBP, EP300	2.06
47	Colorectal cancer	Enrichment	AKT1, EP300, PIK3CA, PIK3R1	2.02
48	Keratolytic winter erythema	Enrichment	CTSB	2.02
49	Macrodactyly	Enrichment	PIK3CA	2.02
50	Boomerang dysplasia	Enrichment	FLNB	2.02
51	Proteus syndrome	Enrichment	AKT1	2.02
52	Spondyloarthropathy 1	Enrichment	HLA-B	2.02
53	Baraitser-winter syndrome 1	Enrichment	ACTB	2.02
54	Focal segmental glomerulosclerosis 1	Enrichment	ACTN4	2.02
55	Otopalatodigital syndrome, type i	Enrichment	FLNA	2.02
56	Intestinal pseudoobstruction, neuronal, chronic idiopathic, x-linked	Enrichment	FLNA	2.02
57	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	2.02
58	Psoriasis 1	Enrichment	HLA-C	2.02
59	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.02
60	Amyloidosis, finnish type	Enrichment	GSN	2.02
61	Dermatitis, atopic, 4	Enrichment	SOCS3	2.02
62	Atelosteogenesis, type iii	Enrichment	FLNB	2.02
63	Atelosteogenesis, type i	Enrichment	FLNB	2.02
64	Cowden syndrome 5	Enrichment	PIK3CA	2.02
65	Immunodeficiency 39 viral infections	Enrichment	IRF7	2.02
66	Encephalopathy, acute, infection-induced 7	Enrichment	IRF3	2.02
67	Pulmonary hypertension, primary, 3	Enrichment	CAV1	2.02
68	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.02
69	Noonan syndrome 13	Enrichment	MAPK1	2.02
70	Immunodeficiency 92	Enrichment	REL	2.02
71	Combined oxidative phosphorylation deficiency 33	Enrichment	C1QBP	2.02
72	Terminal osseous dysplasia	Enrichment	FLNA	2.02
73	Charcot-marie-tooth disease, axonal, type 2b	Enrichment	RAB7A	2.02
74	Leukoencephalopathy, developmental delay, and episodic neurologic regression syndrome	Enrichment	EIF2AK2	2.02
75	Short syndrome	Enrichment	PIK3R1	2.02
76	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	2.02
77	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	2.02
78	Fg syndrome 2	Enrichment	FLNA	2.02
79	Charcot-marie-tooth disease type 2b	Enrichment	RAB7A	2.02
80	Immunodeficiency 39	Enrichment	IRF7	2.02
81	Ankylosing spondylitis 1	Enrichment	HLA-B	2.02
82	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	2.02
83	Pulmonary alveolar proteinosis, acquired	Enrichment	HLA-DRB1	2.02
84	Skin/hair/eye pigmentation, variation in, 10	Enrichment	TPCN2	2.02
85	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.02
86	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.02
87	Otopalatodigital syndrome spectrum disorder	Enrichment	FLNA	2.02
88	Becker nevus syndrome	Enrichment	ACTB	2.02
89	Neurodegeneration due to cerebral folate transport deficiency	Enrichment	FOLR1	2.02
90	Birdshot chorioretinopathy	Enrichment	HLA-A	2.02
91	Dystonia-deafness syndrome 1	Enrichment	ACTB	2.02
92	Immunodeficiency 31a	Enrichment	STAT1	2.02
93	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.02
94	Cowden syndrome 6	Enrichment	AKT1	2.02
95	Graham little-piccardi-lassueur syndrome	Enrichment	HLA-DRA	2.02
96	Bleeding disorder, platelet-type, 15	Enrichment	ACTN1	2.02
97	Dengue virus	Enrichment	CD209	2.02
98	Mannose-binding lectin deficiency	Enrichment	MBL2	2.02
99	Immunodeficiency 14b, autosomal recessive	Enrichment	PIK3CD	2.02
100	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.02
101	Macular degeneration, age-related, 10	Enrichment	TLR4	2.02
102	Immunodeficiency 31b	Enrichment	STAT1	2.02
103	Autoinflammation with arthritis and vasculitis	Enrichment	TBK1	2.02
104	Leukodystrophy, hypomyelinating, 12	Enrichment	VPS11	2.02
105	Reactive arthritis	Enrichment	HLA-B	2.02
106	Singleton-merten syndrome 2	Enrichment	RIGI	2.02
107	T-cell lymphoma, subcutaneous panniculitis-like	Enrichment	HAVCR2	2.02
108	X-linked ehlers-danlos syndrome	Enrichment	FLNA	2.02
109	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.02
110	Takenouchi-kosaki syndrome	Enrichment	CDC42	2.02
111	Corticobasal syndrome	Enrichment	TBK1	2.02
112	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	2.02
113	Immunodeficiency 53	Enrichment	RELB	2.02
114	Berylliosis	Enrichment	HLA-DPB1	2.02
115	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	2.02
116	Dystonia 33	Enrichment	EIF2AK2	2.02
117	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.02
118	Neurodevelopmental disorder with language delay and seizures	Enrichment	TIAM1	2.02
119	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.02
120	Encephalopathy, acute, infection-induced 8	Enrichment	TBK1	2.02
121	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.02
122	Baraitser-winter syndrome	Enrichment	ACTB	2.02
123	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.02
124	Congenital insensitivity to pain with severe intellectual disability	Enrichment	CLTCL1	2.02
125	Hypospadias	Enrichment	PIK3CA	2.02
126	Neurodegenerative syndrome due to cerebral folate transport deficiency	Enrichment	FOLR1	2.02
127	Flnb-related disorders	Enrichment	FLNB	2.02
128	Rare venous malformation	Enrichment	PIK3CA	2.02
129	Fetomaternal alloimmune thrombocytopenia 3	Enrichment	ITGA2	2.02
130	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	2.02
131	Diaphragmatic eventration	Enrichment	PIK3CA	2.02
132	Congenital smooth muscle hamartoma	Enrichment	ACTB	2.02
133	Nocarh syndrome	Enrichment	CDC42	2.02
134	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.02
135	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	2.02
136	Pulmonary arterial hypertension associated with connective tissue disease	Enrichment	HLA-B	2.02
137	Menke-hennekam syndrome	Enrichment	CREBBP	2.02
138	Rare combined vascular malformation	Enrichment	PIK3CA	2.02
139	Cavernous lymphangioma	Enrichment	PIK3CA	2.02
140	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.02
141	X-linked keloid scarring-reduced joint mobility-increased optic cup-to-disc ratio syndrome	Enrichment	FLNA	2.02
142	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.02
143	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.02
144	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.02
145	Macrodactyly of toe	Enrichment	PIK3CA	2.02
146	Human immunodeficiency virus type 1	Enrichment	CD209, HLA-C	1.91
147	Patent foramen ovale	Enrichment	FLNA, FLNC	1.91
148	Behcet syndrome	Enrichment	HLA-B, TLR4	1.86
149	Hyper-igd syndrome	Enrichment	VPS41	1.72
150	Visceral neuropathy, familial, 1, autosomal recessive	Enrichment	FLNA	1.72
151	Thumb deformity	Enrichment	CREBBP	1.72
152	Otopalatodigital syndrome, type ii	Enrichment	FLNA	1.72
153	Melnick-needles syndrome	Enrichment	FLNA	1.72
154	Frontometaphyseal dysplasia 1	Enrichment	FLNA	1.72
155	Spinocerebellar ataxia, autosomal recessive 4	Enrichment	VPS41	1.72
156	Deafness, autosomal dominant 20	Enrichment	ACTG1	1.72
157	Keratosis, seborrheic	Enrichment	PIK3CA	1.72
158	Creutzfeldt-jakob disease	Enrichment	HLA-DQB1	1.72
159	Roifman-chitayat syndrome	Enrichment	PIK3CD	1.72
160	Baraitser-winter syndrome 2	Enrichment	ACTG1	1.72
161	Sarcoidosis 1	Enrichment	HLA-DRB1	1.72
162	Noonan syndrome 8	Enrichment	PIK3CA	1.72
163	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	1.72
164	Immunodeficiency, common variable, 10	Enrichment	NFKB2	1.72
165	Dystonia 16	Enrichment	PRKRA	1.72
166	Immunodeficiency 31c	Enrichment	STAT1	1.72
167	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	1.72
168	Dystonia 30	Enrichment	VPS16	1.72
169	Cardiac valvular dysplasia, x-linked	Enrichment	FLNA	1.72
170	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	1.72
171	Menke-hennekam syndrome 2	Enrichment	EP300	1.72
172	Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome	Enrichment	ITGA3	1.72
173	Stevens-johnson syndrome	Enrichment	HLA-B	1.72
174	Rela fusion-positive ependymoma	Enrichment	RELA	1.72
175	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.72
176	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	1.72
177	Cardiovascular system disease	Enrichment	FLNC	1.72
178	Frontotemporal dementia and/or amyotrophic lateral sclerosis 4	Enrichment	TBK1	1.72
179	Inflammatory skin and bowel disease, neonatal, 1	Enrichment	ADAM17	1.72
180	Cimdag syndrome	Enrichment	VPS4A	1.72
181	Dystonia 32	Enrichment	VPS11	1.72
182	Retinitis pigmentosa 38	Enrichment	MERTK	1.72
183	Esotropia	Enrichment	TFAP2A	1.72
184	Singleton-merten syndrome	Enrichment	RIGI	1.72
185	Qualitative or quantitative defects of caveolin-3	Enrichment	CAV3	1.72
186	Common variable immunodeficiency 12	Enrichment	NFKB1	1.72
187	Lens subluxation	Enrichment	TFAP2A	1.72
188	Cardiomyopathy, familial hypertrophic, 1	Enrichment	CAV3, FLNC	1.67
189	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	1.55
190	Prune belly syndrome	Enrichment	FLNA	1.55
191	Larsen syndrome	Enrichment	FLNB	1.55
192	Arterial tortuosity syndrome	Enrichment	FLNA	1.55
193	Bleeding disorder, platelet-type, 16	Enrichment	ITGB3	1.55
194	Takayasu arteritis	Enrichment	HLA-B	1.55
195	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.55
196	Periventricular nodular heterotopia 1	Enrichment	FLNA	1.55
197	Myopathy, myofibrillar, 5	Enrichment	FLNC	1.55
198	Rippling muscle disease 2	Enrichment	CAV3	1.55
199	Spondylocarpotarsal synostosis syndrome	Enrichment	FLNB	1.55
200	Long qt syndrome 9	Enrichment	CAV3	1.55
201	Nasopharyngeal carcinoma	Enrichment	NPC1	1.55
202	Congenital short bowel syndrome	Enrichment	FLNA	1.55
203	Myopathy, distal, tateyama type	Enrichment	CAV3	1.55
204	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.55
205	Myopathy, distal, 4	Enrichment	FLNC	1.55
206	Epidermolysis bullosa, junctional 6, with pyloric atresia	Enrichment	ITGA6	1.55
207	Intellectual developmental disorder, autosomal dominant 56	Enrichment	CLTC	1.55
208	Tethered spinal cord syndrome	Enrichment	CREBBP	1.55
209	Torsion dystonia 1	Enrichment	EIF2AK2	1.55
210	Frontometaphyseal dysplasia	Enrichment	FLNA	1.55
211	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.55
212	Mucopolysaccharidosis-plus syndrome	Enrichment	VPS33A	1.55
213	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.55
214	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	1.55
215	Adult-onset myasthenia gravis	Enrichment	HLA-DQA1	1.55
216	Spinocerebellar ataxia, autosomal recessive 29	Enrichment	VPS41	1.55
217	Keratoacanthoma	Enrichment	PIK3CA	1.55
218	Vogt-koyanagi-harada disease	Enrichment	HLA-DRB1	1.55
219	Bladder cancer	Enrichment	EGFR, PIK3CA	1.51
220	Lung cancer	Enrichment	EGFR, PIK3CA	1.43
221	Branchiooculofacial syndrome	Enrichment	TFAP2A	1.43
222	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.43
223	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	1.43
224	Immunodeficiency, common variable, 1	Enrichment	NFKB2	1.43
225	Retinitis pigmentosa 26	Enrichment	ITGA4	1.43
226	Aminoacylase 1 deficiency	Enrichment	ACTB	1.43
227	Cardiomyopathy, familial hypertrophic, 26	Enrichment	FLNC	1.43
228	Cerebrovascular disease	Enrichment	PIK3CA	1.43
229	Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 1	Enrichment	CLTC	1.43
230	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CDC42	1.43
231	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.43
232	Systemic-onset juvenile idiopathic arthritis	Enrichment	HLA-DRB1	1.43
233	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.43
234	Familial hypertrophic cardiomyopathy	Enrichment	CAV3, FLNC	1.41
235	Hemifacial hyperplasia	Enrichment	FLNC	1.33
236	Capillary malformations, congenital	Enrichment	PIK3CA	1.33
237	Insulin-like growth factor i	Enrichment	IGF1R	1.33
238	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.33
239	Glanzmann thrombasthenia 2	Enrichment	ITGB3	1.33
240	Follicular lymphoma	Enrichment	HLA-DRB1	1.33
241	Heart conduction disease	Enrichment	FLNC	1.33
242	Amblyopia	Enrichment	TFAP2A	1.33
243	Epidermolysis bullosa	Enrichment	ITGA6	1.33
244	Hemimegalencephaly	Enrichment	PIK3CA	1.33
245	Herpes simplex virus encephalitis	Enrichment	TBK1	1.33
246	Coloboma of choroid and retina	Enrichment	ACTG1	1.33
247	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.25
248	Branchiootorenal syndrome 1	Enrichment	TFAP2A	1.25
249	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGA6	1.25
250	Inflammatory myofibroblastic tumor	Enrichment	CLTC	1.25
251	Patent ductus arteriosus	Enrichment	FLNA	1.25
252	Chronic mucocutaneous candidiasis	Enrichment	STAT1	1.25
253	Hypertrichosis	Enrichment	CREBBP	1.25
254	Inherited arrhythmogenic cardiomyopathy	Enrichment	FLNC	1.25
255	Nevus, epidermal	Enrichment	PIK3CA	1.19
256	Squamous cell carcinoma, head and neck	Enrichment	EGFR	1.19
257	Glanzmann thrombasthenia 1	Enrichment	ITGB3	1.19
258	Capillary malformation-arteriovenous malformation 1	Enrichment	PIK3CA	1.19
259	Noonan syndrome 3	Enrichment	CLTC	1.19
260	Renal cell carcinoma with mit translocations	Enrichment	CLTC	1.19
261	Branchiootorenal syndrome	Enrichment	TFAP2A	1.19
262	Motor neuron disease	Enrichment	TBK1	1.19
263	Gallbladder cancer	Enrichment	PIK3CA	1.19
264	Myofibrillar myopathy	Enrichment	FLNC	1.19
265	Overgrowth syndrome	Enrichment	PIK3R1	1.19
266	Familial isolated restrictive cardiomyopathy	Enrichment	FLNC	1.19
267	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	HLA-C	1.19
268	Hereditary breast carcinoma	Enrichment	AKT1, PIK3CA	1.18
269	Ovarian cancer	Enrichment	AKT1, EGFR, PIK3CA	1.15
270	Myopathy, tubular aggregate, 1	Enrichment	CAV3	1.13
271	Fanconi anemia, complementation group c	Enrichment	FLNA	1.13
272	Thrombocytopenia	Enrichment	ACTN1, ITGB3	1.12
273	Charge syndrome	Enrichment	EP300	1.08
274	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	1.08
275	Arteriovenous malformation	Enrichment	PIK3CA	1.08
276	Adult hepatocellular carcinoma	Enrichment	PIK3CA	1.08
277	Progressive non-fluent aphasia	Enrichment	TBK1	1.08
278	Junctional epidermolysis bullosa	Enrichment	ITGA6	1.08
279	Hypertelorism	Enrichment	PIK3CA, TFAP2A	1.06
280	Frontotemporal dementia and/or amyotrophic lateral sclerosis 1	Enrichment	TBK1	1.04
281	Myopathy, x-linked, with excessive autophagy	Enrichment	PIK3CA	1.04
282	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.04
283	Nemaline myopathy	Enrichment	FLNC	1.04
284	Myeloma, multiple	Enrichment	CREBBP, PIK3R2	1.00
285	Asthma	Enrichment	HLA-G	1.00
286	Heritable pulmonary arterial hypertension	Enrichment	CAV1	1.00
287	Specific learning disability	Enrichment	MAPK1	1.00
288	Cardiac conduction defect	Enrichment	FLNC	0.97
289	Epicanthus	Enrichment	TFAP2A	0.97
290	Restrictive cardiomyopathy	Enrichment	FLNC	0.97
291	Neural tube defects	Enrichment	ITGB1	0.93
292	Lung cancer susceptibility 3	Enrichment	EGFR	0.90
293	Periventricular nodular heterotopia	Enrichment	FLNA	0.90
294	Heart disease	Enrichment	CREBBP	0.90
295	Isolated macular dystrophy	Enrichment	ITGA4	0.90
296	Polydactyly, postaxial, type a1	Enrichment	EP300	0.87
297	Corpus callosum, agenesis of	Enrichment	CREBBP	0.87
298	Lynch syndrome	Enrichment	PIK3CA	0.87
299	Isolated corpus callosum agenesis	Enrichment	CREBBP	0.87
300	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	0.87
301	Creatine phosphokinase, elevated serum	Enrichment	CAV3	0.85
302	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	FLNC	0.85
303	Isolated elevated serum creatine phosphokinase levels	Enrichment	CAV3	0.85
304	Gliosarcoma	Enrichment	EGFR	0.85
305	Cleft palate, isolated	Enrichment	FLNA	0.82
306	Sudden infant death syndrome	Enrichment	CAV3	0.82
307	Giant cell glioblastoma	Enrichment	EGFR	0.82
308	Heart, malformation of	Enrichment	MAPK1	0.80
309	Breast cancer	Enrichment	AKT1, PIK3CA	0.80
310	Arteriovenous malformations of the brain	Enrichment	EGFR	0.78
311	Diffuse large b-cell lymphoma	Enrichment	CREBBP	0.78
312	Cardiomyopathy, dilated, 1a	Enrichment	FLNC	0.74
313	Endometrial cancer	Enrichment	PIK3CA	0.74
314	Lissencephaly	Enrichment	ACTG1	0.74
315	Hepatocellular carcinoma	Enrichment	PIK3CA	0.72
316	Myocardial infarction	Enrichment	ITGB3	0.72
317	Microphthalmia	Enrichment	TFAP2A	0.72
318	Multisystem inflammatory syndrome in children	Enrichment	IRF3	0.72
319	Noonan syndrome 1	Enrichment	RASA2	0.70
320	Scoliosis	Enrichment	CREBBP	0.69
321	Tetralogy of fallot	Enrichment	FLNC	0.66
322	Prostate cancer	Enrichment	PIK3CA	0.62
323	Long qt syndrome 1	Enrichment	CAV3	0.60
324	Long qt syndrome	Enrichment	CAV3	0.59
325	Cystic fibrosis	Enrichment	MBL2	0.58
326	Connective tissue disease	Enrichment	FLNB	0.58
327	Cakut	Enrichment	ACTG1	0.56
328	Genetic steroid-resistant nephrotic syndrome	Enrichment	ACTN4	0.56
329	Dystonia	Enrichment	NPC1	0.55
330	Non-syndromic genetic deafness	Enrichment	ACTG1	0.54
331	Systemic lupus erythematosus	Enrichment	HLA-DRB1	0.51
332	Nonsyndromic hearing loss	Enrichment	ACTG1	0.48
333	Gastric cancer	Enrichment	PIK3CA	0.47
334	Nephrotic syndrome	Enrichment	ITGA3	0.47
335	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	FLNA	0.46
336	Autosomal dominant non-syndromic intellectual disability	Enrichment	CLTC	0.42
337	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ACTG1	0.41
338	Spastic ataxia	Enrichment	FLNC	0.40
339	Undetermined early-onset epileptic encephalopathy	Enrichment	CLTC	0.38
340	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	TBK1	0.37
341	Cone-rod dystrophy 2	Enrichment	ITGA4	0.32
342	Autism	Enrichment	CREBBP	0.30
343	Rare genetic deafness	Enrichment	ACTG1	0.27
344	Dilated cardiomyopathy	Enrichment	FLNC	0.27
345	Mitochondrial disease	Enrichment	C1QBP	0.25
346	Congenital nervous system abnormality	Enrichment	CREBBP	0.20
347	Nervous system disease	Enrichment	CREBBP	0.20
348	Complex neurodevelopmental disorder	Enrichment	TIAM1	0.16
349	Inherited cancer-predisposing syndrome	Enrichment	EGFR	0.14
350	Hereditary retinal dystrophy	Enrichment	ITGA4, MERTK	0.12
351	Fundus dystrophy	Enrichment	ITGA4, MERTK	0.12
352	Retinitis pigmentosa	Enrichment	MERTK	0.06

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Ebola virus infection in host

Pathway Network for Ebola virus infection in host

Member Pathways for Ebola virus infection in host

Pathways in the Ebola virus infection in host SuperPath

Associated Genes for Ebola virus infection in host

Associated Disorders for Ebola virus infection in host

Disorders associated with Ebola virus infection in host SuperPath

STRING Interaction Network for Ebola virus infection in host

Sources for Ebola virus infection in host