Effects of Botulinum toxin

No Pathway Network information available for Effects of Botulinum toxin

Pathways in the Effects of Botulinum toxin SuperPath

#	Name	Source	Genes
1	Effects of Botulinum toxin	PubChem	CHRNA1 RAB3GAP2 RIMS1 SNAP25 STX1A STXBP1 SYT1 UNC13B VAMP2 (see all 9) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RIMS1	Regulating Synaptic Membrane Exocytosis 1	Protein Coding	1
2	UNC13B	Unc-13 Homolog B	Protein Coding	1
3	SNAP25	Synaptosome Associated Protein 25	Protein Coding	1
4	STX1A	Syntaxin 1A	Protein Coding	1
5	STXBP1	Syntaxin Binding Protein 1	Protein Coding	1
6	SYT1	Synaptotagmin 1	Protein Coding	1
7	VAMP2	Vesicle Associated Membrane Protein 2	Protein Coding	1
8	RAB3GAP2	RAB3 GTPase Activating Non-Catalytic Protein Subunit 2	Protein Coding	1
9	CHRNA1	Cholinergic Receptor Nicotinic Alpha 1 Subunit	Protein Coding	1

Disorders associated with Effects of Botulinum toxin SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Autism	Enrichment	CHRNA1, STX1A, STXBP1	4.93
2	Developmental and epileptic encephalopathy	Enrichment	SNAP25, STXBP1	3.61
3	Warburg micro syndrome 2	Enrichment	RAB3GAP2	3.18
4	Developmental and epileptic encephalopathy 117	Enrichment	SNAP25	3.18
5	Baker-gordon syndrome	Enrichment	SYT1	3.18
6	Cone-rod dystrophy 7	Enrichment	RIMS1	3.18
7	Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements	Enrichment	VAMP2	3.18
8	Epilepsy with generalized tonic-clonic seizures	Enrichment	SNAP25	3.18
9	Autosomal recessive spastic paraplegia type 69	Enrichment	RAB3GAP2	3.18
10	9q33.3q34.11 microdeletion syndrome	Enrichment	STXBP1	2.88
11	Gyrate atrophy of choroid and retina	Enrichment	RIMS1	2.70
12	Autism spectrum disorder	Enrichment	RIMS1, STXBP1	2.65
13	Warburg micro syndrome 1	Enrichment	RAB3GAP2	2.58
14	Developmental and epileptic encephalopathy 2	Enrichment	SNAP25	2.58
15	Developmental and epileptic encephalopathy 4	Enrichment	STXBP1	2.58
16	Myasthenic syndrome, congenital, 1b, fast-channel	Enrichment	CHRNA1	2.58
17	Microcephaly	Enrichment	SNAP25, STXBP1	2.55
18	Martsolf syndrome 1	Enrichment	RAB3GAP2	2.48
19	Myasthenic syndrome, congenital, 1a, slow-channel	Enrichment	CHRNA1	2.33
20	Focal epilepsy	Enrichment	SNAP25	2.33
21	Multiple pterygium syndrome, lethal type	Enrichment	CHRNA1	2.28
22	Presynaptic congenital myasthenic syndromes	Enrichment	SNAP25	2.14
23	Postsynaptic congenital myasthenic syndromes	Enrichment	CHRNA1	2.10
24	Stereotypic movement disorder	Enrichment	SNAP25	2.07
25	Congenital myasthenic syndrome	Enrichment	CHRNA1	2.03
26	Syndromic intellectual disability	Enrichment	SYT1	1.95
27	Esophageal atresia/tracheoesophageal fistula	Enrichment	RAB3GAP2	1.90
28	Congenital myopathy	Enrichment	CHRNA1	1.90
29	Williams-beuren syndrome	Enrichment	STX1A	1.88
30	Centronuclear myopathy	Enrichment	CHRNA1	1.86
31	Hydrops fetalis, nonimmune	Enrichment	CHRNA1	1.77
32	Strabismus	Enrichment	STXBP1	1.75
33	Non-immune hydrops fetalis	Enrichment	CHRNA1	1.69
34	Cystic fibrosis	Enrichment	STX1A	1.68
35	Optic atrophy plus syndrome	Enrichment	SNAP25	1.54
36	West syndrome	Enrichment	STXBP1	1.54
37	Spastic ataxia	Enrichment	STXBP1	1.46
38	Cone-rod dystrophy 2	Enrichment	RIMS1	1.35

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Effects of Botulinum toxin

Pathway Network for Effects of Botulinum toxin

Member Pathways for Effects of Botulinum toxin

Pathways in the Effects of Botulinum toxin SuperPath

Associated Genes for Effects of Botulinum toxin

Associated Disorders for Effects of Botulinum toxin

Disorders associated with Effects of Botulinum toxin SuperPath

STRING Interaction Network for Effects of Botulinum toxin

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