Eicosanoid ligand-binding receptors

Sources:

#	Name	Source	Genes
1	Eicosanoid ligand-binding receptors	Reactome	CYSLTR1 CYSLTR2 GPR17 LTB4R LTB4R2 OXER1 PTGDR PTGDR2 PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR TBXA2R (see all 15) (see less)
2	Small ligand GPCRs	WikiPathways	CNR1 CNR2 GPR50 LPAR1 MTNR1A MTNR1B PTAFR PTGDR PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR S1PR1 S1PR2 S1PR3 S1PR4 TBXA2R (see all 19) (see less)
3	Prostanoid ligand receptors	Reactome	PTGDR PTGDR2 PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR TBXA2R (see all 9) (see less)
4	Leukotriene receptors	Reactome	CYSLTR1 CYSLTR2 GPR17 LTB4R LTB4R2

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PTGDR	Prostaglandin D2 Receptor	Protein Coding	3
2	PTGER1	Prostaglandin E Receptor 1	Protein Coding	3
3	PTGER2	Prostaglandin E Receptor 2	Protein Coding	3
4	PTGER3	Prostaglandin E Receptor 3	Protein Coding	3
5	PTGER4	Prostaglandin E Receptor 4	Protein Coding	3
6	PTGFR	Prostaglandin F Receptor	Protein Coding	3
7	PTGIR	Prostaglandin I2 Receptor	Protein Coding	3
8	TBXA2R	Thromboxane A2 Receptor	Protein Coding	3
9	CYSLTR1	Cysteinyl Leukotriene Receptor 1	Protein Coding	2
10	PTGDR2	Prostaglandin D2 Receptor 2	Protein Coding	2
11	LTB4R	Leukotriene B4 Receptor	Protein Coding	2
12	GPR17	G Protein-Coupled Receptor 17	Protein Coding	2
13	LTB4R2	Leukotriene B4 Receptor 2	Protein Coding	2
14	CYSLTR2	Cysteinyl Leukotriene Receptor 2	Protein Coding	2
15	OXER1	Oxoeicosanoid Receptor 1	Protein Coding	1
16	S1PR2	Sphingosine-1-Phosphate Receptor 2	Protein Coding	1
17	GPR50	G Protein-Coupled Receptor 50	Protein Coding	1
18	S1PR4	Sphingosine-1-Phosphate Receptor 4	Protein Coding	1
19	PTAFR	Platelet Activating Factor Receptor	Protein Coding	1
20	MTNR1B	Melatonin Receptor 1B	Protein Coding	1
21	MTNR1A	Melatonin Receptor 1A	Protein Coding	1
22	LPAR1	Lysophosphatidic Acid Receptor 1	Protein Coding	1
23	S1PR1	Sphingosine-1-Phosphate Receptor 1	Protein Coding	1
24	CNR2	Cannabinoid Receptor 2	Protein Coding	1
25	CNR1	Cannabinoid Receptor 1	Protein Coding	1
26	S1PR3	Sphingosine-1-Phosphate Receptor 3	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Asthma-related traits 1	Enrichment	PTGDR	3.18
2	Bleeding disorder, platelet-type, 13	Enrichment	TBXA2R	3.18
3	Bleeding diathesis due to thromboxane synthesis deficiency	Enrichment	TBXA2R	3.18
4	Deafness, autosomal recessive 68	Enrichment	S1PR2	2.85
5	Asthma, nasal polyps, and aspirin intolerance	Enrichment	PTGER2	2.70
6	Melanoma, uveal	Enrichment	CYSLTR2	2.66
7	Type 2 diabetes mellitus	Enrichment	MTNR1B	1.24
8	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	S1PR2	0.93

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Eicosanoid ligand-binding receptors