Eicosanoid metabolism via cytochrome P450 monooxygenases pathway

No Pathway Network information available for Eicosanoid metabolism via cytochrome P450 monooxygenases pathway

#	Name	Source	Genes
1	Eicosanoid metabolism via cytochrome P450 monooxygenases pathway	WikiPathways	CYP4A11 CYP4A22 CYP4F12 CYP4F2 EPHX2 PPARG (see all 6) (see less)
2	α-tocopherol degradation	PubChem	CYP4F2

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CYP4F2	Cytochrome P450 Family 4 Subfamily F Member 2	Protein Coding	2
2	PPARG	Peroxisome Proliferator Activated Receptor Gamma	Protein Coding	1
3	CYP4F12	Cytochrome P450 Family 4 Subfamily F Member 12	Protein Coding	1
4	CYP4A22	Cytochrome P450 Family 4 Subfamily A Member 22	Protein Coding	1
5	EPHX2	Epoxide Hydrolase 2	Protein Coding	1
6	CYP4A11	Cytochrome P450 Family 4 Subfamily A Member 11	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Pparg-associated congenital generalized lipodystrophy	Enrichment	PPARG	3.35
2	Carotid intimal medial thickness 1	Enrichment	PPARG	3.05
3	Familial partial lipodystrophy	Enrichment	PPARG	3.05
4	Lipodystrophy, familial partial, type 3	Enrichment	PPARG	2.75
5	Leptin deficiency or dysfunction	Enrichment	PPARG	2.75
6	Congenital generalized lipodystrophy	Enrichment	PPARG	2.75
7	Hypercholesterolemia, familial, 1	Enrichment	EPHX2	2.24
8	Familial hypercholesterolemia	Enrichment	EPHX2	2.18
9	Gliosarcoma	Enrichment	PPARG	2.15
10	Giant cell glioblastoma	Enrichment	PPARG	2.13
11	Differentiated thyroid carcinoma	Enrichment	PPARG	1.89
12	Type 2 diabetes mellitus	Enrichment	PPARG	1.73
13	Body mass index quantitative trait locus 11	Enrichment	PPARG	1.66
14	Colorectal cancer	Enrichment	PPARG	1.42

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Eicosanoid metabolism via cytochrome P450 monooxygenases pathway