Endoderm differentiation

No Pathway Network information available for Endoderm differentiation

Pathways in the Endoderm differentiation SuperPath

#	Name	Source	Genes
1	Endoderm differentiation	WikiPathways	APC APP BMP7 BMPR1A BPTF CAND1 CDC73 CER1 CTNNB1 CTR9 DAB2 DKK1 DUSP2 DUSP4 DUSP5 ELAVL1 EOMES EPB41L5 EXT1 EZH2 FOXA1 FOXA2 FOXH1 GATA4 GATA6 GDF3 HHEX HNF1B HOXA1 HOXC11 JARID2 LAMC1 LEF1 LEO1 LHX1 MAP2K3 MIR141 MIR373 MIR375 MIXL1 NANOG NKX2-1 NODAL NOG NOTCH1 NR3C1 ONECUT1 OTX2 PABPC1 PAF1 PAX9 POU5F1 PRDM14 PTHLH RAB38 RTF1 SFRP1 SIAH2 SMAD2 SMAD3 SMAD4 SOX17 SOX2 SOX7 STAT1 TBX21 TCF7 TGFB1 TNRC6C WNT3 WNT8A (see all 71) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GDF3	Growth Differentiation Factor 3	Protein Coding	1
2	NOG	Noggin	Protein Coding	1
3	FOXH1	Forkhead Box H1	Protein Coding	1
4	EOMES	Eomesodermin	Protein Coding	1
5	NANOG	Nanog Homeobox	Protein Coding	1
6	CDC73	Cell Division Cycle 73	Protein Coding	1
7	WNT8A	Wnt Family Member 8A	Protein Coding	1
8	WNT3	Wnt Family Member 3	Protein Coding	1
9	NKX2-1	NK2 Homeobox 1	Protein Coding	1
10	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
11	TCF7	Transcription Factor 7	Protein Coding	1
12	HNF1B	HNF1 Homeobox B	Protein Coding	1
13	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	1
14	SOX2	SRY-Box Transcription Factor 2	Protein Coding	1
15	BMPR1A	Bone Morphogenetic Protein Receptor Type 1A	Protein Coding	1
16	BMP7	Bone Morphogenetic Protein 7	Protein Coding	1
17	SIAH2	Siah E3 Ubiquitin Protein Ligase 2	Protein Coding	1
18	SOX17	SRY-Box Transcription Factor 17	Protein Coding	1
19	SFRP1	Secreted Frizzled Related Protein 1	Protein Coding	1
20	PRDM14	PR/SET Domain 14	Protein Coding	1
21	PTHLH	Parathyroid Hormone Like Hormone	Protein Coding	1
22	MAP2K3	Mitogen-Activated Protein Kinase Kinase 3	Protein Coding	1
23	POU5F1	POU Class 5 Homeobox 1	Protein Coding	1
24	LEF1	Lymphoid Enhancer Binding Factor 1	Protein Coding	1
25	PAX9	Paired Box 9	Protein Coding	1
26	OTX2	Orthodenticle Homeobox 2	Protein Coding	1
27	MIR375	MicroRNA 375	RNA Gene	1
28	NOTCH1	Notch Receptor 1	Protein Coding	1
29	NODAL	Nodal Growth Differentiation Factor	Protein Coding	1
30	SMAD4	SMAD Family Member 4	Protein Coding	1
31	SMAD3	SMAD Family Member 3	Protein Coding	1
32	SMAD2	SMAD Family Member 2	Protein Coding	1
33	MIR141	MicroRNA 141	RNA Gene	1
34	LHX1	LIM Homeobox 1	Protein Coding	1
35	LAMC1	Laminin Subunit Gamma 1	Protein Coding	1
36	JARID2	Jumonji And AT-Rich Interaction Domain Containing 2	Protein Coding	1
37	APP	Amyloid Beta Precursor Protein	Protein Coding	1
38	APC	APC Regulator Of Wnt Signaling Pathway	Protein Coding	1
39	HOXA1	Homeobox A1	Protein Coding	1
40	FOXA2	Forkhead Box A2	Protein Coding	1
41	FOXA1	Forkhead Box A1	Protein Coding	1
42	HHEX	Hematopoietically Expressed Homeobox	Protein Coding	1
43	TBX21	T-Box Transcription Factor 21	Protein Coding	1
44	NR3C1	Nuclear Receptor Subfamily 3 Group C Member 1	Protein Coding	1
45	PABPC1	Poly(A) Binding Protein Cytoplasmic 1	Protein Coding	1
46	GATA6	GATA Binding Protein 6	Protein Coding	1
47	GATA4	GATA Binding Protein 4	Protein Coding	1
48	DKK1	Dickkopf Wnt Signaling Pathway Inhibitor 1	Protein Coding	1
49	BPTF	Bromodomain PHD Finger Transcription Factor	Protein Coding	1
50	EZH2	Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit	Protein Coding	1
51	EXT1	Exostosin Glycosyltransferase 1	Protein Coding	1
52	ELAVL1	ELAV Like RNA Binding Protein 1	Protein Coding	1
53	DUSP5	Dual Specificity Phosphatase 5	Protein Coding	1
54	DUSP4	Dual Specificity Phosphatase 4	Protein Coding	1
55	DUSP2	Dual Specificity Phosphatase 2	Protein Coding	1
56	CTNNB1	Catenin Beta 1	Protein Coding	1
57	DAB2	DAB Adaptor Protein 2	Protein Coding	1
58	CTR9	CTR9 Component Of Paf1/RNA Polymerase II Complex	Protein Coding	1
59	CER1	Cerberus 1, DAN Family BMP Antagonist	Protein Coding	1
60	MIXL1	Mix Paired-Like Homeobox	Protein Coding	1
61	LEO1	LEO1 Component Of Paf1/RNA Polymerase II Complex	Protein Coding	1
62	SOX7	SRY-Box Transcription Factor 7	Protein Coding	1
63	TNRC6C	Trinucleotide Repeat Containing Adaptor 6C	Protein Coding	1
64	EPB41L5	Erythrocyte Membrane Protein Band 4.1 Like 5	Protein Coding	1
65	CAND1	Cullin Associated And Neddylation Dissociated 1	Protein Coding	1
66	PAF1	PAF1 Component Of Paf1/RNA Polymerase II Complex	Protein Coding	1
67	MIR373	MicroRNA 373	RNA Gene	1
68	HOXC11	Homeobox C11	Protein Coding	1
69	ONECUT1	One Cut Homeobox 1	Protein Coding	1
70	RAB38	RAB38, Member RAS Oncogene Family	Protein Coding	1
71	RTF1	RTF1 Homolog, Paf1/RNA Polymerase II Complex Component	Protein Coding	1

Disorders associated with Endoderm differentiation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Congenital heart defects, multiple types, 4	Enrichment	BMP7, GATA4, GATA6	5.87
2	Aortic aneurysm, familial thoracic 1	Enrichment	GATA4, NOTCH1, SMAD3	4.32
3	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	NOTCH1, SMAD2, SMAD3, SMAD4	4.10
4	Desmoid disease, hereditary	Enrichment	APC, CTNNB1	4.09
5	Juvenile polyposis syndrome	Enrichment	BMPR1A, SMAD4	4.09
6	Chromosome 17q12 deletion syndrome	Enrichment	HNF1B, LHX1	4.09
7	Desmoid tumor	Enrichment	APC, CTNNB1	4.09
8	Macs syndrome	Enrichment	GDF3, OTX2, SOX2	3.83
9	Craniopharyngioma	Enrichment	APC, CTNNB1	3.79
10	Ovarian cancer	Enrichment	APC, BMPR1A, CTNNB1, EXT1, HNF1B	3.74
11	Ventricular septal defect 1	Enrichment	BMP7, GATA4	3.57
12	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	BMPR1A, SMAD4	3.57
13	Tetralogy of fallot	Enrichment	GATA4, GATA6, NOTCH1	3.48
14	Gallbladder cancer	Enrichment	CTNNB1, SMAD4	3.25
15	Inherited cancer-predisposing syndrome	Enrichment	APC, BMPR1A, CDC73, EZH2, SMAD4	3.20
16	Combined pituitary hormone deficiency	Enrichment	FOXA2, OTX2	3.13
17	Loeys-dietz syndrome	Enrichment	SMAD2, SMAD3	3.02
18	Nanophthalmos	Enrichment	OTX2, SOX2	2.84
19	Septooptic dysplasia	Enrichment	OTX2, SOX2	2.76
20	Medulloblastoma	Enrichment	APC, CTNNB1	2.63
21	46,xy partial gonadal dysgenesis	Enrichment	GATA4, OTX2	2.63
22	Septopreoptic holoprosencephaly	Enrichment	FOXH1, NODAL	2.57
23	Midline interhemispheric variant of holoprosencephaly	Enrichment	FOXH1, NODAL	2.57
24	Microform holoprosencephaly	Enrichment	FOXH1, NODAL	2.51
25	Lobar holoprosencephaly	Enrichment	FOXH1, NODAL	2.51
26	Alobar holoprosencephaly	Enrichment	FOXH1, NODAL	2.46
27	Heart, malformation of	Enrichment	GATA4, NODAL	2.41
28	Patent foramen ovale	Enrichment	GATA4, GATA6	2.41
29	Semilobar holoprosencephaly	Enrichment	FOXH1, NODAL	2.41
30	Chiari malformation type i	Enrichment	DKK1	2.28
31	Chondrosarcoma	Enrichment	EXT1	2.28
32	Stapes ankylosis with broad thumbs and toes	Enrichment	NOG	2.28
33	Tarsal-carpal coalition syndrome	Enrichment	NOG	2.28
34	Parathyroid carcinoma	Enrichment	CDC73	2.28
35	Tooth agenesis, selective, 3	Enrichment	PAX9	2.28
36	Polyposis syndrome, hereditary mixed, 2	Enrichment	BMPR1A	2.28
37	Brachydactyly, type b2	Enrichment	NOG	2.28
38	Hyperparathyroidism 2 with jaw tumors	Enrichment	CDC73	2.28
39	Prostate cancer, hereditary, 11	Enrichment	HNF1B	2.28
40	Symphalangism, proximal, 1a	Enrichment	NOG	2.28
41	Glucocorticoid resistance, generalized	Enrichment	NR3C1	2.28
42	Multiple synostoses syndrome 1	Enrichment	NOG	2.28
43	Vesicoureteral reflux 3	Enrichment	SOX17	2.28
44	Microphthalmia, isolated 7	Enrichment	GDF3	2.28
45	Atrioventricular septal defect 4	Enrichment	GATA4	2.28
46	Atrioventricular septal defect 5	Enrichment	GATA6	2.28
47	Ectodermal dysplasia 17 with or without limb malformations	Enrichment	LEF1	2.28
48	Heterotaxy, visceral, 5, autosomal	Enrichment	NODAL	2.28
49	Developmental delay with variable intellectual disability and dysmorphic facies	Enrichment	JARID2	2.28
50	Microphthalmia, syndromic 5	Enrichment	OTX2	2.28
51	Athabaskan brainstem dysgenesis syndrome	Enrichment	HOXA1	2.28
52	Cerebral amyloid angiopathy, app-related	Enrichment	APP	2.28
53	Atrial septal defect 2	Enrichment	GATA4	2.28
54	Immunodeficiency 31a	Enrichment	STAT1	2.28
55	Klippel-feil syndrome 3, autosomal dominant	Enrichment	GDF3	2.28
56	Pituitary hormone deficiency, combined, 6	Enrichment	OTX2	2.28
57	Testicular anomalies with or without congenital heart disease	Enrichment	GATA4	2.28
58	Brachydactyly, type e2	Enrichment	PTHLH	2.28
59	Loeys-dietz syndrome 6	Enrichment	SMAD2	2.28
60	Immunodeficiency 31b	Enrichment	STAT1	2.28
61	Cdc73-related disorders	Enrichment	CDC73	2.28
62	Atrial septal defect 9	Enrichment	GATA6	2.28
63	Hereditary multiple osteochondromas	Enrichment	EXT1	2.28
64	8p23.1 microdeletion syndrome	Enrichment	GATA4	2.28
65	Exostosis	Enrichment	EXT1	2.28
66	Immunodeficiency 88	Enrichment	TBX21	2.28
67	Congenital heart defects, multiple types, 8, with or without heterotaxy	Enrichment	SMAD2	2.28
68	Adenoid ameloblastoma	Enrichment	CTNNB1	2.28
69	Heritable thoracic aortic disease	Enrichment	SMAD4	2.28
70	Pulmonary hypertension, primary, 7	Enrichment	SOX17	2.28
71	Non-acquired combined pituitary hormone deficiency	Enrichment	FOXA2	2.28
72	Familial adenomatous polyposis	Enrichment	APC	2.28
73	Partial atrioventricular septal defect with ventricular hypoplasia	Enrichment	GATA4	2.28
74	Hereditary multiple exostoses	Enrichment	EXT1	2.28
75	Bosley-salih-alorainy syndrome	Enrichment	HOXA1	2.28
76	Gardner syndrome	Enrichment	APC	2.28
77	Medullary sponge kidney	Enrichment	HNF1B	2.28
78	5q22 microdeletion syndrome	Enrichment	APC	2.28
79	Attenuated familial adenomatous polyposis	Enrichment	APC	2.28
80	Renal dysplasia, bilateral	Enrichment	HNF1B	2.28
81	Unilateral multicystic dysplastic kidney	Enrichment	HNF1B	2.28
82	Renal dysplasia, unilateral	Enrichment	HNF1B	2.28
83	Microcephaly-polymicrogyria-corpus callosum agenesis syndrome	Enrichment	EOMES	2.28
84	Microcystic stromal tumor	Enrichment	CTNNB1	2.28
85	Hepatoblastoma	Enrichment	APC, CTNNB1	2.27
86	Hepatocellular carcinoma	Enrichment	APC, CTNNB1	2.23
87	Microphthalmia	Enrichment	OTX2, SOX2	2.23
88	Familial atrial fibrillation	Enrichment	GATA4, GATA6	2.16
89	Tubulointerstitial kidney disease, autosomal dominant 1	Enrichment	HNF1B	1.98
90	Cerebral amyloid angiopathy, cst3-related	Enrichment	APP	1.98
91	Ectrodactyly and ectodermal dysplasia without cleft lip/palate	Enrichment	LEF1	1.98
92	Exostoses, multiple, type i	Enrichment	EXT1	1.98
93	Renal cysts and diabetes syndrome	Enrichment	HNF1B	1.98
94	Congenital anomalies of kidney and urinary tract 2	Enrichment	HNF1B	1.98
95	Myhre syndrome	Enrichment	SMAD4	1.98
96	Camurati-engelmann disease 1	Enrichment	TGFB1	1.98
97	Galactosemia ii	Enrichment	NR3C1	1.98
98	Agnathia-otocephaly complex	Enrichment	OTX2	1.98
99	Bladder exstrophy and epispadias complex	Enrichment	WNT3	1.98
100	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.98
101	Tetraamelia syndrome 1	Enrichment	WNT3	1.98
102	Hyperparathyroidism 1	Enrichment	CDC73	1.98
103	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	1.98
104	Adams-oliver syndrome 5	Enrichment	NOTCH1	1.98
105	Loeys-dietz syndrome 3	Enrichment	SMAD3	1.98
106	Immunodeficiency 31c	Enrichment	STAT1	1.98
107	Neutropenia, severe congenital, 8, autosomal dominant	Enrichment	GATA6	1.98
108	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.98
109	Hyperuricemic nephropathy, familial juvenile, 3	Enrichment	HNF1B	1.98
110	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	1.98
111	Split hand-foot malformation	Enrichment	LEF1	1.98
112	Camurati-engelmann disease	Enrichment	TGFB1	1.98
113	46,xy sex reversal 3	Enrichment	GATA4	1.98
114	Microphthalmia/coloboma 6	Enrichment	GDF3	1.98
115	Choreoathetosis and congenital hypothyroidism with or without pulmonary dysfunction	Enrichment	NKX2-1	1.98
116	Periampullary adenoma	Enrichment	APC	1.98
117	Gastric adenocarcinoma and proximal polyposis of the stomach	Enrichment	APC	1.98
118	Proximal symphalangism	Enrichment	NOG	1.98
119	17q24.2 microdeletion syndrome	Enrichment	BPTF	1.98
120	Hereditary mixed polyposis syndrome	Enrichment	BMPR1A	1.98
121	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.98
122	Teratoma	Enrichment	CTNNB1	1.98
123	Bladder exstrophy-epispadias-cloacal exstrophy complex	Enrichment	WNT3	1.98
124	Juvenile polyposis of infancy	Enrichment	BMPR1A	1.98
125	Nkx2-1-related disorders	Enrichment	NKX2-1	1.98
126	Colorectal cancer	Enrichment	APC, CTNNB1, SMAD4	1.97
127	Connective tissue disease	Enrichment	NOTCH1, SMAD3	1.92
128	Brachydactyly, type e1	Enrichment	PTHLH	1.81
129	Asthma, nasal polyps, and aspirin intolerance	Enrichment	TBX21	1.81
130	Mullerian duct aplasia, unilateral renal agenesis, and cervicothoracic somite anomalies	Enrichment	HNF1B	1.81
131	Weaver syndrome	Enrichment	EZH2	1.81
132	Heart defects, congenital, and other congenital anomalies	Enrichment	GATA6	1.81
133	Osteoporosis, juvenile	Enrichment	DKK1	1.81
134	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.81
135	Cenani-lenz syndactyly syndrome	Enrichment	APC	1.81
136	Anus, imperforate	Enrichment	CTNNB1	1.81
137	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.81
138	Loeys-dietz syndrome 1	Enrichment	SMAD2	1.81
139	Chromophobe renal cell carcinoma	Enrichment	HNF1B	1.81
140	Familial vesicoureteral reflux	Enrichment	SOX17	1.81
141	Parathyroid adenoma	Enrichment	CDC73	1.81
142	Butterfly-shaped pigment dystrophy	Enrichment	OTX2	1.81
143	Tetraamelia syndrome	Enrichment	WNT3	1.81
144	Familial isolated hyperparathyroidism	Enrichment	CDC73	1.81
145	Colon adenocarcinoma	Enrichment	APC	1.81
146	Keratoacanthoma	Enrichment	NOTCH1	1.81
147	Isolated klippel-feil syndrome	Enrichment	GDF3	1.81
148	Apc-associated polyposis conditions	Enrichment	APC	1.81
149	Kaposi sarcoma	Enrichment	BPTF	1.68
150	Trichorhinophalangeal syndrome, type ii	Enrichment	EXT1	1.68
151	Chorea, benign hereditary	Enrichment	NKX2-1	1.68
152	Microphthalmia, syndromic 3	Enrichment	SOX2	1.68
153	Thyroid cancer, nonmedullary, 1	Enrichment	NKX2-1	1.68
154	Pilomatrixoma	Enrichment	CTNNB1	1.68
155	Alazami syndrome	Enrichment	CTNNB1	1.68
156	Multiple synostoses syndrome	Enrichment	NOG	1.68
157	Hereditary ataxia	Enrichment	NKX2-1	1.68
158	Aortic aneurysm	Enrichment	SMAD3	1.68
159	Transposition of the great arteries	Enrichment	GATA4	1.68
160	Middle aortic syndrome	Enrichment	GATA6	1.68
161	Gastric cancer	Enrichment	APC, SMAD4	1.67
162	Hereditary breast carcinoma	Enrichment	APC, CDC73	1.65
163	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.59
164	Familial adenomatous polyposis 1	Enrichment	APC	1.59
165	Persistent truncus arteriosus	Enrichment	GATA6	1.59
166	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.51
167	Conotruncal heart malformations	Enrichment	GATA6	1.51
168	Split-hand/foot malformation 1	Enrichment	LEF1	1.51
169	Anxiety	Enrichment	OTX2	1.51
170	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.51
171	Adrenocortical carcinoma	Enrichment	CTNNB1	1.51
172	Chronic mucocutaneous candidiasis	Enrichment	STAT1	1.51
173	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	1.51
174	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	GATA4, LEO1	1.46
175	Multiple endocrine neoplasia, type i	Enrichment	CDC73	1.44
176	Hypothyroidism, congenital, nongoitrous, 2	Enrichment	NKX2-1	1.44
177	Adams-oliver syndrome	Enrichment	NOTCH1	1.44
178	Alzheimer's disease 1	Enrichment	APP	1.44
179	Hereditary hemorrhagic telangiectasia	Enrichment	SMAD4	1.44
180	Early-onset autosomal dominant alzheimer disease	Enrichment	APP	1.44
181	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.39
182	Choreatic disease	Enrichment	NKX2-1	1.39
183	Hypoplastic left heart syndrome	Enrichment	NOTCH1	1.39
184	Tooth agenesis, selective, 1	Enrichment	PAX9	1.34
185	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	BPTF	1.34
186	Adult hepatocellular carcinoma	Enrichment	CTNNB1	1.34
187	Primary hyperaldosteronism	Enrichment	NR3C1	1.34
188	Colonic benign neoplasm	Enrichment	APC	1.34
189	Familial thoracic aortic aneurysm and dissection	Enrichment	SMAD3	1.34
190	Heritable pulmonary arterial hypertension	Enrichment	SOX17	1.25
191	Familial colorectal cancer type x	Enrichment	BMPR1A	1.25
192	Breast cancer	Enrichment	APC, CDC73	1.23
193	Aortic valve disease 1	Enrichment	NOTCH1	1.18
194	Diaphragmatic hernia, congenital	Enrichment	GATA6	1.18
195	Pulmonary hypertension, primary, 1	Enrichment	SOX17	1.18
196	Alzheimer's disease	Enrichment	APP	1.18
197	Stereotypic movement disorder	Enrichment	JARID2	1.18
198	Heart disease	Enrichment	GATA4	1.15
199	Renal cell carcinoma, nonpapillary	Enrichment	HNF1B	1.12
200	Wilms tumor 1	Enrichment	CTR9	1.12
201	Wolff-parkinson-white syndrome	Enrichment	NODAL	1.09
202	Alzheimer disease, familial, 1	Enrichment	APP	1.07
203	Polycystic liver disease	Enrichment	CTNNB1	1.07
204	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.07
205	Ehlers-danlos syndrome	Enrichment	SMAD3	1.02
206	Maturity-onset diabetes of the young	Enrichment	HNF1B	1.00
207	Visceral heterotaxy	Enrichment	NODAL	0.96
208	Tooth agenesis	Enrichment	PAX9	0.96
209	Pancreatic cancer	Enrichment	SMAD4	0.91
210	Complex neurodevelopmental disorder	Enrichment	CTR9, JARID2	0.86
211	Bladder cancer	Enrichment	CTNNB1	0.85
212	Prostate cancer	Enrichment	HNF1B	0.85
213	Differentiated thyroid carcinoma	Enrichment	NKX2-1	0.85
214	Visceral heterotaxy 5	Enrichment	NODAL	0.82
215	Cystic fibrosis	Enrichment	TGFB1	0.81
216	Cakut	Enrichment	HNF1B	0.79
217	Type 2 diabetes mellitus	Enrichment	HNF1B	0.70
218	Thrombocytopenia	Enrichment	SMAD4	0.65
219	Autosomal dominant non-syndromic intellectual disability	Enrichment	JARID2	0.64
220	Myeloma, multiple	Enrichment	NKX2-1	0.59
221	Autism	Enrichment	JARID2	0.50
222	Dilated cardiomyopathy	Enrichment	GATA6	0.46
223	Leber plus disease	Enrichment	OTX2	0.40
224	Congenital nervous system abnormality	Enrichment	CTNNB1	0.37
225	Nervous system disease	Enrichment	CTNNB1	0.37
226	Microcephaly	Enrichment	CTNNB1	0.32

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Endoderm differentiation

Pathway Network for Endoderm differentiation

Member Pathways for Endoderm differentiation

Pathways in the Endoderm differentiation SuperPath

Associated Genes for Endoderm differentiation

Associated Disorders for Endoderm differentiation

Disorders associated with Endoderm differentiation SuperPath

STRING Interaction Network for Endoderm differentiation

Sources for Endoderm differentiation