Energy metabolism

No Pathway Network information available for Energy metabolism

Pathways in the Energy metabolism SuperPath

#	Name	Source	Genes
1	Energy metabolism	WikiPathways	ATF2 CAMK2G CAMK4 CREB1 EP300 ESRRA FOXO1 FOXO3 GABPA GSK3B HDAC1 MAPK14 MED1 MEF2A MEF2B MEF2C MEF2D MYBBP1A NCOA1 NRF1 PPARA PPARD PPARG PPARGC1A PPARGC1B PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PPRC1 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PRMT1 RXRA SIRT1 SIRT3 TFAM TFB1M TFB2M UCP2 UCP3 (see all 47) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	1
2	CAMK4	Calcium/Calmodulin Dependent Protein Kinase IV	Protein Coding	1
3	UCP3	Uncoupling Protein 3	Protein Coding	1
4	UCP2	Uncoupling Protein 2	Protein Coding	1
5	TFAM	Transcription Factor A, Mitochondrial	Protein Coding	1
6	RXRA	Retinoid X Receptor Alpha	Protein Coding	1
7	PRKAB1	Protein Kinase AMP-Activated Non-Catalytic Subunit Beta 1	Protein Coding	1
8	PRKAA2	Protein Kinase AMP-Activated Catalytic Subunit Alpha 2	Protein Coding	1
9	PRKAA1	Protein Kinase AMP-Activated Catalytic Subunit Alpha 1	Protein Coding	1
10	PPP3R1	Protein Phosphatase 3 Regulatory Subunit B, Alpha	Protein Coding	1
11	PPP3CC	Protein Phosphatase 3 Catalytic Subunit Gamma	Protein Coding	1
12	PPP3CB	Protein Phosphatase 3 Catalytic Subunit Beta	Protein Coding	1
13	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	1
14	MED1	Mediator Complex Subunit 1	Protein Coding	1
15	PPARG	Peroxisome Proliferator Activated Receptor Gamma	Protein Coding	1
16	PPARD	Peroxisome Proliferator Activated Receptor Delta	Protein Coding	1
17	PPARA	Peroxisome Proliferator Activated Receptor Alpha	Protein Coding	1
18	PRKAG3	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 3	Protein Coding	1
19	PRKAG2	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 2	Protein Coding	1
20	NRF1	Nuclear Respiratory Factor 1	Protein Coding	1
21	MEF2D	Myocyte Enhancer Factor 2D	Protein Coding	1
22	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	1
23	MEF2A	Myocyte Enhancer Factor 2A	Protein Coding	1
24	HDAC1	Histone Deacetylase 1	Protein Coding	1
25	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	1
26	SIRT1	Sirtuin 1	Protein Coding	1
27	SIRT3	Sirtuin 3	Protein Coding	1
28	FOXO3	Forkhead Box O3	Protein Coding	1
29	FOXO1	Forkhead Box O1	Protein Coding	1
30	ESRRA	Estrogen Related Receptor Alpha	Protein Coding	1
31	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
32	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
33	ATF2	Activating Transcription Factor 2	Protein Coding	1
34	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	1
35	PPARGC1B	PPARG Coactivator 1 Beta	Protein Coding	1
36	PPARGC1A	PPARG Coactivator 1 Alpha	Protein Coding	1
37	MYBBP1A	MYB Binding Protein 1a	Protein Coding	1
38	CAMK2G	Calcium/Calmodulin Dependent Protein Kinase II Gamma	Protein Coding	1
39	TFB2M	Transcription Factor B2, Mitochondrial	Protein Coding	1
40	PRKAG1	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 1	Protein Coding	1
41	PRKAB2	Protein Kinase AMP-Activated Non-Catalytic Subunit Beta 2	Protein Coding	1
42	PPP3R2	Protein Phosphatase 3 Regulatory Subunit B, Beta	Protein Coding	1
43	TFB1M	Transcription Factor B1, Mitochondrial	Protein Coding	1
44	PRMT1	Protein Arginine Methyltransferase 1	Protein Coding	1
45	GABPA	GA Binding Protein Transcription Factor Subunit Alpha	Protein Coding	1
46	PPRC1	PPARG Related Coactivator 1	Protein Coding	1
47	MEF2B	Myocyte Enhancer Factor 2B	Protein Coding	1

Disorders associated with Energy metabolism SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Leptin deficiency or dysfunction	Enrichment	PPARG, UCP3	4.15
2	Body mass index quantitative trait locus 11	Enrichment	PPARG, UCP2, UCP3	3.17
3	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	2.46
4	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	2.46
5	Body mass index quantitative trait locus 4	Enrichment	UCP2	2.46
6	Cardiomyopathy, familial hypertrophic, 6	Enrichment	PRKAG2	2.46
7	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	2.46
8	Glycogen storage disease of heart, lethal congenital	Enrichment	PRKAG2	2.46
9	Coronary artery disease, autosomal dominant, 1	Enrichment	MEF2A	2.46
10	Skeletal muscle glycogen content and metabolism quantitative trait locus	Enrichment	PRKAG3	2.46
11	Intellectual developmental disorder, autosomal dominant 59	Enrichment	CAMK2G	2.46
12	Pparg-associated congenital generalized lipodystrophy	Enrichment	PPARG	2.46
13	5q14.3 microdeletion syndrome	Enrichment	MEF2C	2.46
14	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	2.46
15	Mef2c-related disorder	Enrichment	MEF2C	2.46
16	Hyperinsulinism due to ucp2 deficiency	Enrichment	UCP2	2.46
17	Carotid intimal medial thickness 1	Enrichment	PPARG	2.16
18	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	2.16
19	Menke-hennekam syndrome 2	Enrichment	EP300	2.16
20	Mitochondrial dna depletion syndrome 15	Enrichment	TFAM	2.16
21	Familial partial lipodystrophy	Enrichment	PPARG	2.16
22	Melanoma of soft tissue	Enrichment	CREB1	1.98
23	Lipodystrophy, familial partial, type 3	Enrichment	PPARG	1.86
24	Congenital generalized lipodystrophy	Enrichment	PPARG	1.86
25	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MEF2C, PPARGC1A	1.77
26	Rhabdomyosarcoma 2	Enrichment	FOXO1	1.76
27	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.76
28	Rubinstein-taybi syndrome 1	Enrichment	EP300	1.69
29	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	EP300	1.69
30	Charge syndrome	Enrichment	EP300	1.51
31	Rare mitochondrial non-syndromic sensorineural deafness	Enrichment	TFB1M	1.47
32	Colorectal cancer	Enrichment	EP300, PPARG	1.44
33	Polydactyly, postaxial, type a1	Enrichment	EP300	1.29
34	Rare genetic intellectual disability	Enrichment	EP300	1.29
35	Wolff-parkinson-white syndrome	Enrichment	PRKAG2	1.27
36	Gliosarcoma	Enrichment	PPARG	1.27
37	Giant cell glioblastoma	Enrichment	PPARG	1.24
38	Diffuse large b-cell lymphoma	Enrichment	FOXO1	1.19
39	Differentiated thyroid carcinoma	Enrichment	PPARG	1.02
40	Familial hypertrophic cardiomyopathy	Enrichment	PRKAG2	0.97
41	Type 2 diabetes mellitus	Enrichment	PPARG	0.87
42	Hypertrophic cardiomyopathy	Enrichment	PRKAG2	0.86
43	Autosomal dominant non-syndromic intellectual disability	Enrichment	PPP3CA	0.80
44	Myeloma, multiple	Enrichment	RXRA	0.75
45	Undetermined early-onset epileptic encephalopathy	Enrichment	PPP3CA	0.75
46	Autism	Enrichment	CAMK2G	0.65
47	Autism spectrum disorder	Enrichment	MEF2C	0.50
48	Microcephaly	Enrichment	EP300	0.46

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Energy metabolism

Member Pathways for Energy metabolism

Pathways in the Energy metabolism SuperPath

Associated Genes for Energy metabolism

Associated Disorders for Energy metabolism

Disorders associated with Energy metabolism SuperPath

STRING Interaction Network for Energy metabolism

Sources for Energy metabolism