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ERK Signaling SuperPath

Pathway network for ERK Signaling SuperPath
5 Pathways in the ERK Signaling SuperPath
Molecular Mechanisms of Cancer ILK Signaling
Rho Family GTPases ERK Signaling
MAPK Signaling
1185 Genes in the ERK Signaling SuperPath
ACAN ALK ANGPTL6 AREG AXL BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5
BMP6 BMP7 BMP8A BTC COL10A1 COL11A1 COL11A2 COL12A1 COL13A1 COL14A1 COL15A1 COL16A1
COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL27A1 COL2A1
COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2
COL6A3 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 HAPLN1 CSF1R VCAN NCAN SMC3
CCN2 CXCL12 DDR1 DDR2 FREM2 EPYC LEFTY2 TYMP ECM1 ECM2 EFEMP1 EFEMP2
EGF EGFR ELN EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2
EPHB3 EPHB4 EPHB6 EPOR ERBB2 ERBB3 ERBB4 FBN1 FBN2 FBN3 FGF1 FGF10
FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22
FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 VEGFD FREM1
FLT1 FLT3 FLT4 FN1 FOS FRAS1 GAS1 GAS2 GAS6 GAS8 GDF10 GDF2
GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNRH1 GNRH2 GPC6 HAPLN2
HAPLN3 HAPLN4 HDGF HGF HSPG2 IGF1 IGF1R IGF2 IGF2-AS IL2 IL3 IL6
IL9 IMPG1 IMPG2 INSR INSRR ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1
ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JUN KDR COL20A1 KIT KITLG
LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3
LEFTY1 LHB LIFR LMTK2 LMTK3 NRG4 LTBP1 LTBP2 LTBP3 LTBP4 MAPK1 MAPK3
MDK MEPE MERTK MET MMRN2 MST1R MUSK NFKB1 NGF NRG1 NRG2 NRG3
NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN PIK3R5 PDGFA PDGFB PDGFC PDGFRA
PDGFRB PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 GDF15 PLPP3 PPBP PRG2 PRG4
PROK1 PSIP1 PTK2 PTK2B PTK7 PTN RAC1 ROR1 ROR2 ROS1 RYK PDGFD
CLEC11A SEMA3A SEMA4B SEMA4G SEMA5A SPOCK1 SPOCK2 SPOCK3 SPON1 SPON2 SPP1 TBRG1
TDGF1 TEK TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 KLF10 TIMP1 TIMP2 TIMP3
TIMP4 TNC TNF TYRO3 UTS2 VEGFB VEGFC BCL2 CDC42 ELK1 GNA11 GNA12
GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ
GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4
GNG5 GNG7 GNG8 GNGT1 GNGT2 IL1A IL1B ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B
ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 LTA MAP2K1 MAP2K2 MAPK10 MAPK8
MAPK9 MYC OSM PAK1 RAF1 ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7
ADCY8 ADCY9 ANGPT1 ANGPT2 ANGPT4 ANGPTL1 RHOA RHOB RHOC RHOD RND3 RHOG
ARHGEF6 RHOH DIRAS3 RND2 BAD BAX BMP15 BMP8B BRAF BTK CCL1 CCL11
CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23
CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL4 CCL4L1 CCL4L2 CCL5 CCL7
CCL8 CD2 CD80 CDH1 CER1 CSF1 CSF2 CSF3 CX3CL1 CXCL1 CXCL10 CXCL11
CXCL13 CXCL14 CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL9 DAP GRB2 HRAS IL10
IL11 IL12A IL12B IL13 IL15 IL16 IL17A IL18 IL19 IL20 IL21 IL22
IL23A IL24 IL26 IL4 IL5 IL7 CXCL8 KRAS LIF MAP2K3 MAP2K6 MAP2K7
MRAS NRAS PF4 PF4V1 PIP PLCB1 PLCB2 PLCB3 PLCB4 PPBPP2 PRKACA PRKACB
PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKD1
PRKD3 PRKCQ RAC2 RAC3 RAP1A RAP1B RRAS RRAS2 SOS1 SOS2 SRC TCF3
TCF4 TNFRSF1A TNFSF10 TNFSF11 TNFSF12 TNFSF13 TNFSF13B TNFSF14 TNFSF18 TNFSF4 CD40LG FASLG
CD70 TNFSF8 TNFSF9 TP53 ATF1 ATF4 CHUK CREB1 CREB3 CREB3L4 RPS6KA4 RPS6KA5
PAK2 PAK3 PAK4 PAK6 PAK5 PRKCI PRKCZ AKT1 AKT2 AKT3 ARHGEF1 ARHGEF10
ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF2 ARHGEF3 ARHGEF4 ARHGEF5 ARHGEF7 ARHGEF9 CASP3 CASP9
CCND1 CTNNB1 ELK3 ELK4 MTOR GSK3A GSK3B HIF1A IL1R1 IL2RA IRS1 LEF1
MAP3K5 MAP3K7 MAPK11 MAPK12 MAPK13 MAPK14 MAPK6 MAPK7 MAX MCF2L NET1 NFKBIA
NGFR PDPK1 PTEN TGFBR1 TNFRSF1B TRADD ATF2 ATF3 ATF5 ATF6 ATF7 BCAR1
GCFC2 CDH10 CDH11 CDH12 CDH13 CDH15 CDH16 CDH17 CDH18 CDH19 CDH2 CDH3
CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CEBPB CFL1 CFL2 HNF4A MYL9 NFE2L1
PPP1R14B PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PTPA PPP2R5A PPP2R5B
PPP2R5C PPP2R5E PPP2R3B PXN HNF1A TCF12 TCF15 TCF19 HNF1B TCF20 TCF21 TCF23
TCF7 TCF7L2 ZEB1 TEAD1 TEAD4 TFAM VIM ZNF354A MAP2K4 MAP2K5 MAP3K10 MAP3K11
MYLK PPP1R12A PPP1R12B ARAF CNKSR1 LAMTOR3 MKNK1 MKNK2 PLCG1 RPS6KA1 RPS6KA2 RPS6KA3
RPS6KA6 STAT1 STAT3 ABL1 ABL2 ACVR1 ACVR2B ACVRL1 ADAM17 APAF1 APC APH1A
ATM ATR AURKB AURKC AXIN1 BAK1 BBC3 BCL2L1 BCL2L11 BID BIRC2 BIRC3
CXCR5 BMPR1A BMPR1B BMPR2 BRCA1 CAMK2A CAMK2B CAMK2D CAMK2G CASP10 CASP6 CASP7
CASP8 CBL CCND2 CCND3 CCNE1 CCNE2 CCR1 CCR2 CCR3 CCR4 CCR5 CCR6
CCR7 CCR8 CCR9 CCRL2 CD28 CD4 CDK1 CDC25A CDC25B CDC25C CDK2 CDK4
CDK6 CDKN1A CDKN1B CDKN2A CDKN2B CDKN2C CDKN2D CFLAR CHEK1 CHEK2 CREBBP CRK
CSF2RA CSF2RB CSF3R CTNNA1 CTNNA2 CTNNA3 CTNND1 CX3CR1 CXCR3 CXCR4 CXCR6 CYCS
DHH DVL1 E2F1 E2F2 E2F3 E2F4 E2F5 EP300 FADD FANCD2 FOXO1 FPR2
FYN FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GAB1
GAB2 GLI1 GNB1L RACK1 CCR10 HAT1 HIPK2 HRH4 IHH IL10RA IL10RB IL11RA
IL12RB1 IL12RB2 IL13RA1 IL13RA2 IL15RA IL17RA IL17RC IL18R1 IL20RA IL22RA1 IL23R IL2RB
IL2RG IL3RA IL4R IL5RA IL6R IL7R CXCR1 CXCR2 IL9R JAK1 JAK2 JAK3
LRP5 LRP6 SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 TAB1 TAB2 MDM2 TUBB6
TUBB2B NBN NCSTN NF1 NFKBIB NFKBIE NLK NOTCH1 NOTCH2 NOTCH3 NOTCH4 NUMB
OSMR PSENEN PIK3C2G PIK3CG PMAIP1 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3
PRKDC PSEN1 PSEN2 APH1B PTCH1 PTCH2 RAD51 RALA RALB RALBP1 RALGDS RAP2A
RAP2B RAP2C RAPGEF1 RPTOR RARA RARB RARG RASA1 RASGRF1 RASGRF2 RASGRP1 RASGRP2
RB1 RBL1 RBPJ RHEB NPTN DIABLO SMO SOX1 SOX10 SOX11 SOX12 SOX13
SOX14 SOX15 SOX17 SOX18 SOX2 SOX21 SOX3 SOX30 SOX4 SOX5 SOX6 SOX7
SOX8 SOX9 STK11 STK36 AURKA SUFU SYNGAP1 TGFBR2 TNFAIP6 TNFRSF10A TNFRSF10B TNFRSF10C
TNFRSF10D TNFRSF11A TNFRSF25 TNFRSF12A TNFRSF13B TNFRSF13C TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF21 TNFRSF4 CD40
FAS TNFRSF6B CD27 TNFRSF8 TNFRSF9 TSC1 TSC2 TUBA4A TUBA3C TUBA8 TUBB1 TUBB2A
TUBB3 TUBB7P TUBD1 TUBE1 TUBG1 TUBG2 VHL WEE1 WNT1 WNT5A XCR1 ACTA1
ACTA2 ACTB ACTG1 ACTG2 ACTN1 ACTN2 ACTN3 ACTN4 RHOJ RHOQ CDH20 CDH22
CDH23 CDH24 CDH26 DOCK1 DSP FBLIM1 FLNA FLNB FLNC FOSB FOSL1 FOSL2
MYL11 ILK IRS2 IRS4 JUNB JUND MYH15 KRT18 LIMS1 LIMS2 CLEC18C MUC1
MYH1 MYH10 MYH11 MYH13 MYH14 MYH2 MYH3 MYH4 MYH6 MYH7 MYH7B MYH8
MYH9 MYL1 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7 MYO10 MYO15A MYO18B MYO1A
MYO1B MYO1C MYO1D MYO1E MYO1F MYO1G MYO3A MYO3B MYO5A MYO6 MYO7A MYO9A
MYO9B NACA NCK2 NOS2 PARVA PARVB DCHS1 FERMT2 PPP2R5D PTGS2 RSU1 SNAI1
SNAI2 TESK1 TGFB1I1 TMSB4X TMSB4Y VEGFA PABPC4-AS1 PCDH9-AS3 PCYT1B-AS1 ACTR2 ACTR3 ARFIP2
ARHGDIA ARHGDIB BAIAP2 SEPTIN7 CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42EP5 CIT CYFIP1 DES
DIAPH3 SEPTIN11 GFAP IQGAP1 LIMK1 LIMK2 MAP3K9 SEPTIN9 MSN NCF2 SEPTIN2 PARD3
PARD6A PIP5K1A PIP5K1B PIP5K1C PIP4K2A PIP4K2B PIP4K2C PLD1 SEPTIN5 SEPTIN4 PKN1 RDX
ROCK1 ROCK2 CLIP1 SLC9A1 STMN1 EZR WASF1 WASF3 WASL WIPF1 BRF1 CACNA1A
CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3
CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7
CACNG8 CAPN1 CAPN10 CAPN11 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN9 CAPNS1 CD3D
CD3E CD3G CD247 DUSP1 DUSP3 ESR1 ESR2 ETS1 ETS2 H3-3A H3-3B H3C1
H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3C10 H3C11 H3C12 H3-4 HMGN1 LAT
PAX6 PPP1R10 PPP1R11 PPP1R12C PPP1R13B PPP1R14A PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A
PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B SRF TP53BP2 UBTF ZAP70
CLEC14A DDIT3 HBEGF GLG1 HSF1 IGF2R IL1R2 IRAK1 IRAK2 IRAK3 IRAK4 MAP3K2
MAP3K3 MAP3K4 MAP3K8 MAPK8IP1 MAPK8IP2 MAPK8IP3 MAPKAPK2 MEF2A MEF2C MEF2D NRP1 NRP2
OGFR PLCD1 PLCD3 PLCD4 PLCE1 PLCG2 PLCZ1 WNK1 RIPK1 SH3RF1 STAT2 STAT4
STAT5A STAT5B STAT6 TGFBR3 TLN1 TLN2 TRAF2 TRAF6 VCL
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for ERK Signaling SuperPath