ERK Signaling

Pathway network for the ERK Signaling SuperPath

Sources:

QIAGEN

Pathways in the ERK Signaling SuperPath

#	Name	Source	Genes
1	ERK Signaling	QIAGEN	ACAN ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ALK ANGPT1 ANGPT2 ANGPT4 ANGPTL1 ANGPTL6 ARAF AREG ATF1 ATF4 AXL BAD BAX BCL2 BDNF BMP1 BMP10 BMP15 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BMP8B BRAF BRF1 BTC BTK CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CAPN1 CAPN10 CAPN11 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN9 CAPNS1 CCL1 CCL11 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL4 CCL4L1 CCL4L2 CCL5 CCL7 CCL8 CCN2 CD2 CD247 CD3D CD3E CD3G CD40LG CD70 CD80 CER1 CHUK CLEC11A CNKSR1 COL10A1 COL11A1 COL11A2 COL12A1 COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL20A1 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL27A1 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 CREB1 CREB3 CREB3L4 CRIPTO CSF1 CSF1R CSF2 CSF3 CX3CL1 CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCL9 DAP DDR1 DDR2 DRC4 DUSP1 DUSP3 ECM1 ECM2 EFEMP1 EFEMP2 EGF EGFR ELK1 ELK3 ELK4 ELN EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR EPYC ERBB2 ERBB3 ERBB4 ESR1 ESR2 ETS1 ETS2 FASLG FBN1 FBN2 FBN3 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 FN1 FOS FRAS1 FREM1 FREM2 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GNRH1 GNRH2 GPC6 GRB2 H3-3A H3-3B H3-4 H3C1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 HAPLN1 HAPLN2 HAPLN3 HAPLN4 HDGF HGF HMGN1 HRAS HSPG2 IGF1 IGF1R IGF2 IGF2-AS IL10 IL11 IL12A IL12B IL13 IL15 IL16 IL17A IL18 IL19 IL1A IL1B IL2 IL20 IL21 IL22 IL23A IL24 IL26 IL3 IL4 IL5 IL6 IL7 IL9 IMPG1 IMPG2 INSR INSRR ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JUN KDR KIT KITLG KLF10 KRAS LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 LAMTOR3 LAT LEFTY1 LEFTY2 LHB LIF LIFR LMTK2 LMTK3 LTA LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAPK1 MAPK3 MAX MDK MEPE MERTK MET MKNK1 MKNK2 MMRN2 MRAS MST1R MUSK MYC MYLK NCAN NFKB1 NFKBIA NGF NRAS NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN OSM PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PAX6 PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PF4 PF4V1 PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PIP PLCB1 PLCB2 PLCB3 PLCB4 PLCG1 PLPP3 PPBP PPBPP2 PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R13B PPP1R14A PPP1R14B PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PPP2R3B PPP2R5A PPP2R5B PPP2R5C PPP2R5E PRG2 PRG4 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 PROK1 PSIP1 PTK2 PTK2B PTK7 PTN PTPA RAC1 RAF1 RAP1A RAP1B ROR1 ROR2 ROS1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA5 RPS6KA6 RRAS RRAS2 RYK SEMA3A SEMA4B SEMA4G SEMA5A SMC3 SOS1 SOS2 SPOCK1 SPOCK2 SPOCK3 SPON1 SPON2 SPP1 SRC SRF STAT1 STAT3 TBRG1 TEK TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TNC TNF TNFSF10 TNFSF11 TNFSF12 TNFSF13 TNFSF13B TNFSF14 TNFSF18 TNFSF4 TNFSF8 TNFSF9 TP53 TP53BP2 TYMP TYRO3 UBTF UTS2 VCAN VEGFB VEGFC VEGFD ZAP70 (see all 607) (see less)
2	Molecular Mechanisms of Cancer	QIAGEN	ABL1 ABL2 ACAN ACVR1 ACVR2B ACVRL1 ADAM17 ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 AKT1 AKT2 AKT3 ALK ANGPT1 ANGPT2 ANGPT4 ANGPTL1 ANGPTL6 APAF1 APC APH1A APH1B AREG ARHGEF1 ARHGEF10 ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF2 ARHGEF3 ARHGEF4 ARHGEF5 ARHGEF6 ARHGEF7 ARHGEF9 ATM ATR AURKA AURKB AURKC AXIN1 AXL BAD BAK1 BAX BBC3 BCL2 BCL2L1 BCL2L11 BDNF BID BIRC2 BIRC3 BMP1 BMP10 BMP15 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BMP8B BMPR1A BMPR1B BMPR2 BRAF BRCA1 BTC BTK CAMK2A CAMK2B CAMK2D CAMK2G CASP10 CASP3 CASP6 CASP7 CASP8 CASP9 CBL CCL1 CCL11 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL4 CCL4L1 CCL4L2 CCL5 CCL7 CCL8 CCN2 CCND1 CCND2 CCND3 CCNE1 CCNE2 CCR1 CCR10 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCRL2 CD2 CD27 CD28 CD4 CD40 CD40LG CD70 CD80 CDC25A CDC25B CDC25C CDC42 CDH1 CDK1 CDK2 CDK4 CDK6 CDKN1A CDKN1B CDKN2A CDKN2B CDKN2C CDKN2D CER1 CFLAR CHEK1 CHEK2 CLEC11A COL10A1 COL11A1 COL11A2 COL12A1 COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL20A1 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL27A1 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 CREBBP CRIPTO CRK CSF1 CSF1R CSF2 CSF2RA CSF2RB CSF3 CSF3R CTNNA1 CTNNA2 CTNNA3 CTNNB1 CTNND1 CX3CL1 CX3CR1 CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCL9 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CYCS DAP DDR1 DDR2 DHH DIABLO DIRAS3 DRC4 DVL1 E2F1 E2F2 E2F3 E2F4 E2F5 ECM1 ECM2 EFEMP1 EFEMP2 EGF EGFR ELK1 ELK3 ELK4 ELN EP300 EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR EPYC ERBB2 ERBB3 ERBB4 FADD FANCD2 FAS FASLG FBN1 FBN2 FBN3 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 FN1 FOS FOXO1 FPR2 FRAS1 FREM1 FREM2 FYN FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GAB1 GAB2 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLI1 GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB1L GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GNRH1 GNRH2 GPC6 GRB2 GSK3A GSK3B HAPLN1 HAPLN2 HAPLN3 HAPLN4 HAT1 HDGF HGF HIF1A HIPK2 HRAS HRH4 HSPG2 IGF1 IGF1R IGF2 IGF2-AS IHH IL10 IL10RA IL10RB IL11 IL11RA IL12A IL12B IL12RB1 IL12RB2 IL13 IL13RA1 IL13RA2 IL15 IL15RA IL16 IL17A IL17RA IL17RC IL18 IL18R1 IL19 IL1A IL1B IL1R1 IL2 IL20 IL20RA IL21 IL22 IL22RA1 IL23A IL23R IL24 IL26 IL2RA IL2RB IL2RG IL3 IL3RA IL4 IL4R IL5 IL5RA IL6 IL6R IL7 IL7R IL9 IL9R IMPG1 IMPG2 INSR INSRR IRS1 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JAK1 JAK2 JAK3 JUN KDR KIT KITLG KLF10 KRAS LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 LEF1 LEFTY1 LEFTY2 LHB LIF LIFR LMTK2 LMTK3 LRP5 LRP6 LTA LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAP2K3 MAP2K6 MAP2K7 MAP3K5 MAP3K7 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK6 MAPK7 MAPK8 MAPK9 MAX MCF2L MDK MDM2 MEPE MERTK MET MMRN2 MRAS MST1R MTOR MUSK MYC NBN NCAN NCSTN NET1 NF1 NFKB1 NFKBIA NFKBIB NFKBIE NGF NGFR NLK NOTCH1 NOTCH2 NOTCH3 NOTCH4 NPTN NRAS NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 NUMB OGN OSM OSMR PAK1 PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PDPK1 PENK PF4 PF4V1 PGF PIK3C2G PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PIP PLCB1 PLCB2 PLCB3 PLCB4 PLPP3 PMAIP1 PPBP PPBPP2 PRG2 PRG4 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKACA PRKACB PRKACG PRKAG1 PRKAG2 PRKAG3 PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ PRKD1 PRKD3 PRKDC PROK1 PSEN1 PSEN2 PSENEN PSIP1 PTCH1 PTCH2 PTEN PTK2 PTK2B PTK7 PTN RAC1 RAC2 RAC3 RACK1 RAD51 RAF1 RALA RALB RALBP1 RALGDS RAP1A RAP1B RAP2A RAP2B RAP2C RAPGEF1 RARA RARB RARG RASA1 RASGRF1 RASGRF2 RASGRP1 RASGRP2 RB1 RBL1 RBPJ RHEB RHOA RHOB RHOC RHOD RHOG RHOH RND2 RND3 ROR1 ROR2 ROS1 RPTOR RRAS RRAS2 RYK SEMA3A SEMA4B SEMA4G SEMA5A SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMC3 SMO SOS1 SOS2 SOX1 SOX10 SOX11 SOX12 SOX13 SOX14 SOX15 SOX17 SOX18 SOX2 SOX21 SOX3 SOX30 SOX4 SOX5 SOX6 SOX7 SOX8 SOX9 SPOCK1 SPOCK2 SPOCK3 SPON1 SPON2 SPP1 SRC STK11 STK36 SUFU SYNGAP1 TAB1 TAB2 TBRG1 TCF3 TCF4 TEK TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TNC TNF TNFAIP6 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF13C TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF1A TNFRSF1B TNFRSF21 TNFRSF25 TNFRSF4 TNFRSF6B TNFRSF8 TNFRSF9 TNFSF10 TNFSF11 TNFSF12 TNFSF13 TNFSF13B TNFSF14 TNFSF18 TNFSF4 TNFSF8 TNFSF9 TP53 TRADD TSC1 TSC2 TUBA3C TUBA4A TUBA8 TUBB1 TUBB2A TUBB2B TUBB3 TUBB6 TUBB7P TUBD1 TUBE1 TUBG1 TUBG2 TYMP TYRO3 UTS2 VCAN VEGFB VEGFC VEGFD VHL WEE1 WNT1 WNT5A XCR1 (see all 814) (see less)
3	Rho Family GTPases	QIAGEN	ACAN ACTR2 ACTR3 ALK ANGPT1 ANGPT2 ANGPT4 ANGPTL1 ANGPTL6 AREG ARFIP2 ARHGDIA ARHGDIB ARHGEF1 ARHGEF10 ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF2 ARHGEF3 ARHGEF4 ARHGEF5 ARHGEF6 ARHGEF7 ARHGEF9 AXL BAIAP2 BAX BCL2 BDNF BMP1 BMP10 BMP15 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BMP8B BTC BTK CCL1 CCL11 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL4 CCL4L1 CCL4L2 CCL5 CCL7 CCL8 CCN2 CD2 CD40LG CD70 CD80 CDC42 CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42EP5 CDH1 CDH10 CDH11 CDH12 CDH13 CDH15 CDH16 CDH17 CDH18 CDH19 CDH2 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CER1 CFL1 CFL2 CIT CLEC11A CLIP1 COL10A1 COL11A1 COL11A2 COL12A1 COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL20A1 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL27A1 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 CRIPTO CSF1 CSF1R CSF2 CSF3 CX3CL1 CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCL9 CYFIP1 DAP DDR1 DDR2 DES DIAPH3 DIRAS3 DRC4 ECM1 ECM2 EFEMP1 EFEMP2 EGF EGFR ELK1 ELN EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR EPYC ERBB2 ERBB3 ERBB4 EZR FASLG FBN1 FBN2 FBN3 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 FN1 FOS FRAS1 FREM1 FREM2 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFAP GFER GH1 GH2 GHRH GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GNRH1 GNRH2 GPC6 HAPLN1 HAPLN2 HAPLN3 HAPLN4 HDGF HGF HSPG2 IGF1 IGF1R IGF2 IGF2-AS IL10 IL11 IL12A IL12B IL13 IL15 IL16 IL17A IL18 IL19 IL1A IL1B IL2 IL20 IL21 IL22 IL23A IL24 IL26 IL3 IL4 IL5 IL6 IL7 IL9 IMPG1 IMPG2 INSR INSRR IQGAP1 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JUN KDR KIT KITLG KLF10 LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 LEFTY1 LEFTY2 LHB LIF LIFR LIMK1 LIMK2 LMTK2 LMTK3 LTA LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAP2K7 MAP3K10 MAP3K11 MAP3K9 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MCF2L MDK MEPE MERTK MET MMRN2 MSN MST1R MUSK MYL9 MYLK NCAN NCF2 NET1 NFKB1 NGF NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN OSM PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PARD3 PARD6A PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PF4 PF4V1 PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PIP PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PKN1 PLD1 PLPP3 PPBP PPBPP2 PPP1R12A PPP1R12B PRG2 PRG4 PRKCI PRKCZ PROK1 PSIP1 PTK2 PTK2B PTK7 PTN RAC1 RAC2 RAC3 RAF1 RDX RHOA RHOB RHOC RHOD RHOG RHOH RND2 RND3 ROCK1 ROCK2 ROR1 ROR2 ROS1 RYK SEMA3A SEMA4B SEMA4G SEMA5A SEPTIN11 SEPTIN2 SEPTIN4 SEPTIN5 SEPTIN7 SEPTIN9 SLC9A1 SMC3 SPOCK1 SPOCK2 SPOCK3 SPON1 SPON2 SPP1 STMN1 TBRG1 TEK TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TNC TNF TNFSF10 TNFSF11 TNFSF12 TNFSF13 TNFSF13B TNFSF14 TNFSF18 TNFSF4 TNFSF8 TNFSF9 TYMP TYRO3 UTS2 VCAN VEGFB VEGFC VEGFD VIM WASF1 WASF3 WASL WIPF1 (see all 545) (see less)
4	MAPK Signaling	QIAGEN	ACAN ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ALK ANGPTL6 ARAF AREG ATF1 ATF2 ATF3 ATF4 ATF5 ATF6 ATF7 AXL BCAR1 BCL2 BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BRAF BTC CCN2 CDC42 CEBPB CHUK CLEC11A CLEC14A CNKSR1 COL10A1 COL11A1 COL11A2 COL12A1 COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL20A1 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL27A1 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 CREB1 CREB3 CREB3L4 CRIPTO CSF1R CXCL12 DDIT3 DDR1 DDR2 DRC4 ECM1 ECM2 EFEMP1 EFEMP2 EGF EGFR ELK1 ELN EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR EPYC ERBB2 ERBB3 ERBB4 FBN1 FBN2 FBN3 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 FN1 FOS FRAS1 FREM1 FREM2 GAS1 GAS2 GAS6 GCFC2 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GNRH1 GNRH2 GPC6 GRB2 HAPLN1 HAPLN2 HAPLN3 HAPLN4 HBEGF HDGF HGF HNF1A HNF1B HNF4A HRAS HSF1 HSPG2 IGF1 IGF1R IGF2 IGF2-AS IGF2R IL1A IL1B IL1R1 IL1R2 IL2 IL2RA IL3 IL6 IL9 IMPG1 IMPG2 INSR INSRR IRAK1 IRAK2 IRAK3 IRAK4 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JUN KDR KIT KITLG KLF10 KRAS LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 LAMTOR3 LEFTY1 LEFTY2 LHB LIFR LMTK2 LMTK3 LTA LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAP2K7 MAP3K10 MAP3K11 MAP3K2 MAP3K3 MAP3K4 MAP3K5 MAP3K7 MAP3K8 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK7 MAPK8 MAPK8IP1 MAPK8IP2 MAPK8IP3 MAPK9 MAPKAPK2 MDK MEF2A MEF2C MEF2D MEPE MERTK MET MKNK1 MKNK2 MMRN2 MRAS MST1R MUSK MYC NCAN NFE2L1 NFKB1 NGF NGFR NRAS NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN OSM PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PLPP3 PPBP PRG2 PRG4 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 PROK1 PSIP1 PTK2 PTK2B PTK7 PTN PXN RAC1 RAF1 RAP1A RAP1B RIPK1 ROR1 ROR2 ROS1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA5 RPS6KA6 RRAS RRAS2 RYK SEMA3A SEMA4B SEMA4G SEMA5A SH3RF1 SMC3 SOS1 SOS2 SPOCK1 SPOCK2 SPOCK3 SPON1 SPON2 SPP1 SRC STAT1 STAT2 STAT3 STAT4 STAT5A STAT5B STAT6 TBRG1 TCF12 TCF15 TCF19 TCF20 TCF21 TCF23 TCF3 TCF4 TCF7 TCF7L2 TEAD1 TEAD4 TEK TFAM TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TLN1 TLN2 TNC TNF TNFRSF1A TNFRSF1B TP53 TRADD TRAF2 TRAF6 TYMP TYRO3 UTS2 VCAN VCL VEGFB VEGFC VEGFD WNK1 ZEB1 ZNF354A (see all 504) (see less)
5	ILK Signaling	QIAGEN	ACAN ACTA1 ACTA2 ACTB ACTG1 ACTG2 ACTN1 ACTN2 ACTN3 ACTN4 AKT1 AKT2 AKT3 ALK ANGPTL6 AREG ARHGEF6 ATF1 ATF2 ATF3 ATF4 ATF5 ATF6 ATF7 AXL BAD BCAR1 BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CASP3 CASP9 CCN2 CCND1 CDC42 CDH1 CDH10 CDH11 CDH12 CDH13 CDH15 CDH16 CDH17 CDH18 CDH19 CDH2 CDH20 CDH22 CDH23 CDH24 CDH26 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CEBPB CFL1 CFL2 CHUK CLEC11A CLEC18C COL10A1 COL11A1 COL11A2 COL12A1 COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL20A1 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL27A1 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 CREB1 CREB3 CREB3L4 CRIPTO CSF1R CTNNB1 CXCL12 DCHS1 DDR1 DDR2 DIRAS3 DOCK1 DRC4 DSP ECM1 ECM2 EFEMP1 EFEMP2 EGF EGFR ELN EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR EPYC ERBB2 ERBB3 ERBB4 FBLIM1 FBN1 FBN2 FBN3 FERMT2 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLNA FLNB FLNC FLT1 FLT3 FLT4 FN1 FOS FOSB FOSL1 FOSL2 FRAS1 FREM1 FREM2 GAS1 GAS2 GAS6 GCFC2 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNRH1 GNRH2 GPC6 GSK3A GSK3B HAPLN1 HAPLN2 HAPLN3 HAPLN4 HDGF HGF HIF1A HNF1A HNF1B HNF4A HSPG2 IGF1 IGF1R IGF2 IGF2-AS IL2 IL3 IL6 IL9 ILK IMPG1 IMPG2 INSR INSRR IRS1 IRS2 IRS4 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JUN JUNB JUND KDR KIT KITLG KLF10 KRT18 LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 LEF1 LEFTY1 LEFTY2 LHB LIFR LIMS1 LIMS2 LMTK2 LMTK3 LTBP1 LTBP2 LTBP3 LTBP4 MAPK1 MAPK10 MAPK3 MAPK6 MAPK8 MAPK9 MDK MEPE MERTK MET MMRN2 MST1R MTOR MUC1 MUSK MYC MYH1 MYH10 MYH11 MYH13 MYH14 MYH15 MYH2 MYH3 MYH4 MYH6 MYH7 MYH7B MYH8 MYH9 MYL1 MYL11 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7 MYL9 MYO10 MYO15A MYO18B MYO1A MYO1B MYO1C MYO1D MYO1E MYO1F MYO1G MYO3A MYO3B MYO5A MYO6 MYO7A MYO9A MYO9B NACA NCAN NCK2 NFE2L1 NFKB1 NGF NOS2 NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN PARVA PARVB PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PDPK1 PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLPP3 PPBP PPP1R14B PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PPP2R3B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRG2 PRG4 PROK1 PSIP1 PTEN PTGS2 PTK2 PTK2B PTK7 PTN PTPA PXN RAC1 RAC2 RAC3 RHOA RHOB RHOC RHOD RHOG RHOH RHOJ RHOQ RND2 RND3 ROR1 ROR2 ROS1 RPS6KA4 RPS6KA5 RSU1 RYK SEMA3A SEMA4B SEMA4G SEMA5A SMC3 SNAI1 SNAI2 SPOCK1 SPOCK2 SPOCK3 SPON1 SPON2 SPP1 TBRG1 TCF12 TCF15 TCF19 TCF20 TCF21 TCF23 TCF3 TCF4 TCF7 TCF7L2 TEAD1 TEAD4 TEK TESK1 TFAM TGFA TGFB1 TGFB1I1 TGFB2 TGFB3 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TMSB4X TMSB4Y TNC TNF TNFRSF1A TYMP TYRO3 UTS2 VCAN VEGFA VEGFB VEGFC VEGFD VIM ZEB1 ZNF354A (see all 481) (see less)

Gene overlap in member pathways for ERK Signaling SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACAN	Aggrecan	Protein Coding	5
2	ALK	ALK Receptor Tyrosine Kinase	Protein Coding	5
3	ANGPTL6	Angiopoietin Like 6	Protein Coding	5
4	AREG	Amphiregulin	Protein Coding	5
5	AXL	AXL Receptor Tyrosine Kinase	Protein Coding	5
6	BDNF	Brain Derived Neurotrophic Factor	Protein Coding	5
7	BMP1	Bone Morphogenetic Protein 1	Protein Coding	5
8	BMP10	Bone Morphogenetic Protein 10	Protein Coding	5
9	BMP2	Bone Morphogenetic Protein 2	Protein Coding	5
10	BMP3	Bone Morphogenetic Protein 3	Protein Coding	5
11	BMP4	Bone Morphogenetic Protein 4	Protein Coding	5
12	BMP5	Bone Morphogenetic Protein 5	Protein Coding	5
13	BMP6	Bone Morphogenetic Protein 6	Protein Coding	5
14	BMP7	Bone Morphogenetic Protein 7	Protein Coding	5
15	BMP8A	Bone Morphogenetic Protein 8a	Protein Coding	5
16	BTC	Betacellulin	Protein Coding	5
17	COL10A1	Collagen Type X Alpha 1 Chain	Protein Coding	5
18	COL11A1	Collagen Type XI Alpha 1 Chain	Protein Coding	5
19	COL11A2	Collagen Type XI Alpha 2 Chain	Protein Coding	5
20	COL12A1	Collagen Type XII Alpha 1 Chain	Protein Coding	5
21	COL13A1	Collagen Type XIII Alpha 1 Chain	Protein Coding	5
22	COL14A1	Collagen Type XIV Alpha 1 Chain	Protein Coding	5
23	COL15A1	Collagen Type XV Alpha 1 Chain	Protein Coding	5
24	COL16A1	Collagen Type XVI Alpha 1 Chain	Protein Coding	5
25	COL17A1	Collagen Type XVII Alpha 1 Chain	Protein Coding	5
26	COL18A1	Collagen Type XVIII Alpha 1 Chain	Protein Coding	5
27	COL19A1	Collagen Type XIX Alpha 1 Chain	Protein Coding	5
28	COL1A1	Collagen Type I Alpha 1 Chain	Protein Coding	5
29	COL1A2	Collagen Type I Alpha 2 Chain	Protein Coding	5
30	COL21A1	Collagen Type XXI Alpha 1 Chain	Protein Coding	5
31	COL22A1	Collagen Type XXII Alpha 1 Chain	Protein Coding	5
32	COL23A1	Collagen Type XXIII Alpha 1 Chain	Protein Coding	5
33	COL24A1	Collagen Type XXIV Alpha 1 Chain	Protein Coding	5
34	COL25A1	Collagen Type XXV Alpha 1 Chain	Protein Coding	5
35	COL27A1	Collagen Type XXVII Alpha 1 Chain	Protein Coding	5
36	COL2A1	Collagen Type II Alpha 1 Chain	Protein Coding	5
37	COL3A1	Collagen Type III Alpha 1 Chain	Protein Coding	5
38	COL4A1	Collagen Type IV Alpha 1 Chain	Protein Coding	5
39	COL4A2	Collagen Type IV Alpha 2 Chain	Protein Coding	5
40	COL4A3	Collagen Type IV Alpha 3 Chain	Protein Coding	5
41	COL4A4	Collagen Type IV Alpha 4 Chain	Protein Coding	5
42	COL4A5	Collagen Type IV Alpha 5 Chain	Protein Coding	5
43	COL4A6	Collagen Type IV Alpha 6 Chain	Protein Coding	5
44	COL5A1	Collagen Type V Alpha 1 Chain	Protein Coding	5
45	COL5A2	Collagen Type V Alpha 2 Chain	Protein Coding	5
46	COL5A3	Collagen Type V Alpha 3 Chain	Protein Coding	5
47	COL6A1	Collagen Type VI Alpha 1 Chain	Protein Coding	5
48	COL6A2	Collagen Type VI Alpha 2 Chain	Protein Coding	5
49	COL6A3	Collagen Type VI Alpha 3 Chain	Protein Coding	5
50	COL7A1	Collagen Type VII Alpha 1 Chain	Protein Coding	5
51	COL8A1	Collagen Type VIII Alpha 1 Chain	Protein Coding	5
52	COL8A2	Collagen Type VIII Alpha 2 Chain	Protein Coding	5
53	COL9A1	Collagen Type IX Alpha 1 Chain	Protein Coding	5
54	COL9A2	Collagen Type IX Alpha 2 Chain	Protein Coding	5
55	COL9A3	Collagen Type IX Alpha 3 Chain	Protein Coding	5
56	HAPLN1	Hyaluronan And Proteoglycan Link Protein 1	Protein Coding	5
57	CSF1R	Colony Stimulating Factor 1 Receptor	Protein Coding	5
58	VCAN	Versican	Protein Coding	5
59	NCAN	Neurocan	Protein Coding	5
60	SMC3	Structural Maintenance Of Chromosomes 3	Protein Coding	5
61	CCN2	Cellular Communication Network Factor 2	Protein Coding	5
62	CXCL12	C-X-C Motif Chemokine Ligand 12	Protein Coding	5
63	DDR1	Discoidin Domain Receptor Tyrosine Kinase 1	Protein Coding	5
64	DDR2	Discoidin Domain Receptor Tyrosine Kinase 2	Protein Coding	5
65	FREM2	FRAS1 Related Extracellular Matrix 2	Protein Coding	5
66	EPYC	Epiphycan	Protein Coding	5
67	LEFTY2	Left-Right Determination Factor 2	Protein Coding	5
68	TYMP	Thymidine Phosphorylase	Protein Coding	5
69	ECM1	Extracellular Matrix Protein 1	Protein Coding	5
70	ECM2	Extracellular Matrix Protein 2	Protein Coding	5
71	EFEMP1	EGF-Like Fibulin Extracellular Matrix Protein 1	Protein Coding	5
72	EFEMP2	EGF-Like Fibulin Extracellular Matrix Protein 2	Protein Coding	5
73	EGF	Epidermal Growth Factor	Protein Coding	5
74	EGFR	Epidermal Growth Factor Receptor	Protein Coding	5
75	ELN	Elastin	Protein Coding	5
76	EPHA1	EPH Receptor A1	Protein Coding	5
77	EPHA2	EPH Receptor A2	Protein Coding	5
78	EPHA3	EPH Receptor A3	Protein Coding	5
79	EPHA4	EPH Receptor A4	Protein Coding	5
80	EPHA5	EPH Receptor A5	Protein Coding	5
81	EPHA7	EPH Receptor A7	Protein Coding	5
82	EPHA8	EPH Receptor A8	Protein Coding	5
83	EPHB1	EPH Receptor B1	Protein Coding	5
84	EPHB2	EPH Receptor B2	Protein Coding	5
85	EPHB3	EPH Receptor B3	Protein Coding	5
86	EPHB4	EPH Receptor B4	Protein Coding	5
87	EPHB6	EPH Receptor B6	Protein Coding	5
88	EPOR	Erythropoietin Receptor	Protein Coding	5
89	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	5
90	ERBB3	Erb-B2 Receptor Tyrosine Kinase 3	Protein Coding	5
91	ERBB4	Erb-B2 Receptor Tyrosine Kinase 4	Protein Coding	5
92	FBN1	Fibrillin 1	Protein Coding	5
93	FBN2	Fibrillin 2	Protein Coding	5
94	FBN3	Fibrillin 3	Protein Coding	5
95	FGF1	Fibroblast Growth Factor 1	Protein Coding	5
96	FGF10	Fibroblast Growth Factor 10	Protein Coding	5
97	FGF11	Fibroblast Growth Factor 11	Protein Coding	5
98	FGF12	Fibroblast Growth Factor 12	Protein Coding	5
99	FGF13	Fibroblast Growth Factor 13	Protein Coding	5
100	FGF14	Fibroblast Growth Factor 14	Protein Coding	5
101	FGF16	Fibroblast Growth Factor 16	Protein Coding	5
102	FGF17	Fibroblast Growth Factor 17	Protein Coding	5
103	FGF18	Fibroblast Growth Factor 18	Protein Coding	5
104	FGF19	Fibroblast Growth Factor 19	Protein Coding	5
105	FGF2	Fibroblast Growth Factor 2	Protein Coding	5
106	FGF20	Fibroblast Growth Factor 20	Protein Coding	5
107	FGF21	Fibroblast Growth Factor 21	Protein Coding	5
108	FGF22	Fibroblast Growth Factor 22	Protein Coding	5
109	FGF23	Fibroblast Growth Factor 23	Protein Coding	5
110	FGF4	Fibroblast Growth Factor 4	Protein Coding	5
111	FGF5	Fibroblast Growth Factor 5	Protein Coding	5
112	FGF6	Fibroblast Growth Factor 6	Protein Coding	5
113	FGF7	Fibroblast Growth Factor 7	Protein Coding	5
114	FGF8	Fibroblast Growth Factor 8	Protein Coding	5
115	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	5
116	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	5
117	FGFR3	Fibroblast Growth Factor Receptor 3	Protein Coding	5
118	FGFR4	Fibroblast Growth Factor Receptor 4	Protein Coding	5
119	VEGFD	Vascular Endothelial Growth Factor D	Protein Coding	5
120	FREM1	FRAS1 Related Extracellular Matrix 1	Protein Coding	5
121	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	5
122	FLT3	Fms Related Receptor Tyrosine Kinase 3	Protein Coding	5
123	FLT4	Fms Related Receptor Tyrosine Kinase 4	Protein Coding	5
124	FN1	Fibronectin 1	Protein Coding	5
125	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	5
126	FRAS1	Fraser Extracellular Matrix Complex Subunit 1	Protein Coding	5
127	GAS1	Growth Arrest Specific 1	Protein Coding	5
128	GAS2	Growth Arrest Specific 2	Protein Coding	5
129	GAS6	Growth Arrest Specific 6	Protein Coding	5
130	DRC4	Dynein Regulatory Complex Subunit 4	Protein Coding	5
131	GDF10	Growth Differentiation Factor 10	Protein Coding	5
132	GDF2	Growth Differentiation Factor 2	Protein Coding	5
133	GDF5	Growth Differentiation Factor 5	Protein Coding	5
134	GDF6	Growth Differentiation Factor 6	Protein Coding	5
135	GDF9	Growth Differentiation Factor 9	Protein Coding	5
136	GFER	Growth Factor, Augmenter Of Liver Regeneration	Protein Coding	5
137	GH1	Growth Hormone 1	Protein Coding	5
138	GH2	Growth Hormone 2	Protein Coding	5
139	GHRH	Growth Hormone Releasing Hormone	Protein Coding	5
140	GMFG	Glia Maturation Factor Gamma	Protein Coding	5
141	GNRH1	Gonadotropin Releasing Hormone 1	Protein Coding	5
142	GNRH2	Gonadotropin Releasing Hormone 2	Protein Coding	5
143	GPC6	Glypican 6	Protein Coding	5
144	HAPLN2	Hyaluronan And Proteoglycan Link Protein 2	Protein Coding	5
145	HAPLN3	Hyaluronan And Proteoglycan Link Protein 3	Protein Coding	5
146	HAPLN4	Hyaluronan And Proteoglycan Link Protein 4	Protein Coding	5
147	HDGF	Heparin Binding Growth Factor	Protein Coding	5
148	HGF	Hepatocyte Growth Factor	Protein Coding	5
149	HSPG2	Heparan Sulfate Proteoglycan 2	Protein Coding	5
150	IGF1	Insulin Like Growth Factor 1	Protein Coding	5
151	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	5
152	IGF2	Insulin Like Growth Factor 2	Protein Coding	5
153	IGF2-AS	IGF2 Antisense RNA	RNA Gene	5
154	IL2	Interleukin 2	Protein Coding	5
155	IL3	Interleukin 3	Protein Coding	5
156	IL6	Interleukin 6	Protein Coding	5
157	IL9	Interleukin 9	Protein Coding	5
158	IMPG1	Interphotoreceptor Matrix Proteoglycan 1	Protein Coding	5
159	IMPG2	Interphotoreceptor Matrix Proteoglycan 2	Protein Coding	5
160	INSR	Insulin Receptor	Protein Coding	5
161	INSRR	Insulin Receptor Related Receptor	Protein Coding	5
162	ITGAD	Integrin Subunit Alpha D	Protein Coding	5
163	ITGAE	Integrin Subunit Alpha E	Protein Coding	5
164	ITGAL	Integrin Subunit Alpha L	Protein Coding	5
165	ITGAM	Integrin Subunit Alpha M	Protein Coding	5
166	ITGAV	Integrin Subunit Alpha V	Protein Coding	5
167	ITGAX	Integrin Subunit Alpha X	Protein Coding	5
168	ITGB1	Integrin Subunit Beta 1	Protein Coding	5
169	ITGB2	Integrin Subunit Beta 2	Protein Coding	5
170	ITGB3	Integrin Subunit Beta 3	Protein Coding	5
171	ITGB4	Integrin Subunit Beta 4	Protein Coding	5
172	ITGB5	Integrin Subunit Beta 5	Protein Coding	5
173	ITGB6	Integrin Subunit Beta 6	Protein Coding	5
174	ITGB7	Integrin Subunit Beta 7	Protein Coding	5
175	ITGB8	Integrin Subunit Beta 8	Protein Coding	5
176	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	5
177	KDR	Kinase Insert Domain Receptor	Protein Coding	5
178	COL20A1	Collagen Type XX Alpha 1 Chain	Protein Coding	5
179	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	5
180	KITLG	KIT Ligand	Protein Coding	5
181	LAMA1	Laminin Subunit Alpha 1	Protein Coding	5
182	LAMA2	Laminin Subunit Alpha 2	Protein Coding	5
183	LAMA3	Laminin Subunit Alpha 3	Protein Coding	5
184	LAMA4	Laminin Subunit Alpha 4	Protein Coding	5
185	LAMA5	Laminin Subunit Alpha 5	Protein Coding	5
186	LAMB1	Laminin Subunit Beta 1	Protein Coding	5
187	LAMB2	Laminin Subunit Beta 2	Protein Coding	5
188	LAMB3	Laminin Subunit Beta 3	Protein Coding	5
189	LAMB4	Laminin Subunit Beta 4	Protein Coding	5
190	LAMC1	Laminin Subunit Gamma 1	Protein Coding	5
191	LAMC2	Laminin Subunit Gamma 2	Protein Coding	5
192	LAMC3	Laminin Subunit Gamma 3	Protein Coding	5
193	LEFTY1	Left-Right Determination Factor 1	Protein Coding	5
194	LHB	Luteinizing Hormone Subunit Beta	Protein Coding	5
195	LIFR	LIF Receptor Subunit Alpha	Protein Coding	5
196	LMTK2	Lemur Tyrosine Kinase 2	Protein Coding	5
197	LMTK3	Lemur Tyrosine Kinase 3	Protein Coding	5
198	LTBP1	Latent Transforming Growth Factor Beta Binding Protein 1	Protein Coding	5
199	LTBP2	Latent Transforming Growth Factor Beta Binding Protein 2	Protein Coding	5
200	LTBP3	Latent Transforming Growth Factor Beta Binding Protein 3	Protein Coding	5
201	LTBP4	Latent Transforming Growth Factor Beta Binding Protein 4	Protein Coding	5
202	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	5
203	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	5
204	MDK	Midkine	Protein Coding	5
205	MEPE	Matrix Extracellular Phosphoglycoprotein	Protein Coding	5
206	MERTK	MER Proto-Oncogene, Tyrosine Kinase	Protein Coding	5
207	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	5
208	MMRN2	Multimerin 2	Protein Coding	5
209	MST1R	Macrophage Stimulating 1 Receptor	Protein Coding	5
210	MUSK	Muscle Associated Receptor Tyrosine Kinase	Protein Coding	5
211	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	5
212	NGF	Nerve Growth Factor	Protein Coding	5
213	NRG1	Neuregulin 1	Protein Coding	5
214	NRG2	Neuregulin 2	Protein Coding	5
215	NRG3	Neuregulin 3	Protein Coding	5
216	NTF3	Neurotrophin 3	Protein Coding	5
217	NTF4	Neurotrophin 4	Protein Coding	5
218	NTRK1	Neurotrophic Receptor Tyrosine Kinase 1	Protein Coding	5
219	NTRK2	Neurotrophic Receptor Tyrosine Kinase 2	Protein Coding	5
220	NTRK3	Neurotrophic Receptor Tyrosine Kinase 3	Protein Coding	5
221	NUDT6	Nudix Hydrolase 6	Protein Coding	5
222	OGN	Osteoglycin	Protein Coding	5
223	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	5
224	PDGFA	Platelet Derived Growth Factor Subunit A	Protein Coding	5
225	PDGFB	Platelet Derived Growth Factor Subunit B	Protein Coding	5
226	PDGFC	Platelet Derived Growth Factor C	Protein Coding	5
227	PDGFRA	Platelet Derived Growth Factor Receptor Alpha	Protein Coding	5
228	PDGFRB	Platelet Derived Growth Factor Receptor Beta	Protein Coding	5
229	PENK	Proenkephalin	Protein Coding	5
230	PGF	Placental Growth Factor	Protein Coding	5
231	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	5
232	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	5
233	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	5
234	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	5
235	GDF15	Growth Differentiation Factor 15	Protein Coding	5
236	PLPP3	Phospholipid Phosphatase 3	Protein Coding	5
237	PPBP	Pro-Platelet Basic Protein	Protein Coding	5
238	PRG2	Proteoglycan 2, Pro Eosinophil Major Basic Protein	Protein Coding	5
239	PRG4	Proteoglycan 4	Protein Coding	5
240	PROK1	Prokineticin 1	Protein Coding	5
241	PSIP1	PC4 And SRSF1 Interacting Protein 1	Protein Coding	5
242	PTK2	Protein Tyrosine Kinase 2	Protein Coding	5
243	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	5
244	PTK7	Protein Tyrosine Kinase 7 (Inactive)	Protein Coding	5
245	PTN	Pleiotrophin	Protein Coding	5
246	RAC1	Rac Family Small GTPase 1	Protein Coding	5
247	ROR1	Receptor Tyrosine Kinase Like Orphan Receptor 1	Protein Coding	5
248	ROR2	Receptor Tyrosine Kinase Like Orphan Receptor 2	Protein Coding	5
249	ROS1	ROS Proto-Oncogene 1, Receptor Tyrosine Kinase	Protein Coding	5
250	RYK	Receptor Like Tyrosine Kinase	Protein Coding	5
251	PDGFD	Platelet Derived Growth Factor D	Protein Coding	5
252	CLEC11A	C-Type Lectin Domain Containing 11A	Protein Coding	5
253	SEMA3A	Semaphorin 3A	Protein Coding	5
254	SEMA4B	Semaphorin 4B	Protein Coding	5
255	SEMA4G	Semaphorin 4G	Protein Coding	5
256	SEMA5A	Semaphorin 5A	Protein Coding	5
257	SPOCK1	SPARC (Osteonectin), Cwcv And Kazal Like Domains Proteoglycan 1	Protein Coding	5
258	SPOCK2	SPARC (Osteonectin), Cwcv And Kazal Like Domains Proteoglycan 2	Protein Coding	5
259	SPOCK3	SPARC (Osteonectin), Cwcv And Kazal Like Domains Proteoglycan 3	Protein Coding	5
260	SPON1	Spondin 1	Protein Coding	5
261	SPON2	Spondin 2	Protein Coding	5
262	SPP1	Secreted Phosphoprotein 1	Protein Coding	5
263	TBRG1	Transforming Growth Factor Beta Regulator 1	Protein Coding	5
264	CRIPTO	Cripto, EGF-CFC Family Member	Protein Coding	5
265	TEK	TEK Receptor Tyrosine Kinase	Protein Coding	5
266	TGFA	Transforming Growth Factor Alpha	Protein Coding	5
267	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	5
268	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	5
269	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	5
270	THPO	Thrombopoietin	Protein Coding	5
271	TIE1	Tyrosine Kinase With Immunoglobulin Like And EGF Like Domains 1	Protein Coding	5
272	KLF10	KLF Transcription Factor 10	Protein Coding	5
273	TIMP1	TIMP Metallopeptidase Inhibitor 1	Protein Coding	5
274	TIMP2	TIMP Metallopeptidase Inhibitor 2	Protein Coding	5
275	TIMP3	TIMP Metallopeptidase Inhibitor 3	Protein Coding	5
276	TIMP4	TIMP Metallopeptidase Inhibitor 4	Protein Coding	5
277	TNC	Tenascin C	Protein Coding	5
278	TNF	Tumor Necrosis Factor	Protein Coding	5
279	TYRO3	TYRO3 Protein Tyrosine Kinase	Protein Coding	5
280	UTS2	Urotensin 2	Protein Coding	5
281	VEGFB	Vascular Endothelial Growth Factor B	Protein Coding	5
282	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	5
283	BCL2	BCL2 Apoptosis Regulator	Protein Coding	4
284	ELK1	ETS Transcription Factor ELK1	Protein Coding	4
285	GNA11	G Protein Subunit Alpha 11	Protein Coding	4
286	GNA12	G Protein Subunit Alpha 12	Protein Coding	4
287	GNA13	G Protein Subunit Alpha 13	Protein Coding	4
288	GNA14	G Protein Subunit Alpha 14	Protein Coding	4
289	GNA15	G Protein Subunit Alpha 15	Protein Coding	4
290	GNAI1	G Protein Subunit Alpha I1	Protein Coding	4
291	GNAI2	G Protein Subunit Alpha I2	Protein Coding	4
292	GNAI3	G Protein Subunit Alpha I3	Protein Coding	4
293	GNAL	G Protein Subunit Alpha L	Protein Coding	4
294	GNAO1	G Protein Subunit Alpha O1	Protein Coding	4
295	GNAS	GNAS Complex Locus	Protein Coding	4
296	GNAT1	G Protein Subunit Alpha Transducin 1	Protein Coding	4
297	GNAT2	G Protein Subunit Alpha Transducin 2	Protein Coding	4
298	GNAZ	G Protein Subunit Alpha Z	Protein Coding	4
299	GNB1	G Protein Subunit Beta 1	Protein Coding	4
300	GNB2	G Protein Subunit Beta 2	Protein Coding	4
301	GNB3	G Protein Subunit Beta 3	Protein Coding	4
302	GNB4	G Protein Subunit Beta 4	Protein Coding	4
303	GNB5	G Protein Subunit Beta 5	Protein Coding	4
304	GNG10	G Protein Subunit Gamma 10	Protein Coding	4
305	GNG11	G Protein Subunit Gamma 11	Protein Coding	4
306	GNG12	G Protein Subunit Gamma 12	Protein Coding	4
307	GNG13	G Protein Subunit Gamma 13	Protein Coding	4
308	GNG2	G Protein Subunit Gamma 2	Protein Coding	4
309	GNG3	G Protein Subunit Gamma 3	Protein Coding	4
310	GNG4	G Protein Subunit Gamma 4	Protein Coding	4
311	GNG5	G Protein Subunit Gamma 5	Protein Coding	4
312	GNG7	G Protein Subunit Gamma 7	Protein Coding	4
313	GNG8	G Protein Subunit Gamma 8	Protein Coding	4
314	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	4
315	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	4
316	IL1A	Interleukin 1 Alpha	Protein Coding	4
317	IL1B	Interleukin 1 Beta	Protein Coding	4
318	ITGA1	Integrin Subunit Alpha 1	Protein Coding	4
319	ITGA10	Integrin Subunit Alpha 10	Protein Coding	4
320	ITGA11	Integrin Subunit Alpha 11	Protein Coding	4
321	ITGA2	Integrin Subunit Alpha 2	Protein Coding	4
322	ITGA2B	Integrin Subunit Alpha 2b	Protein Coding	4
323	ITGA3	Integrin Subunit Alpha 3	Protein Coding	4
324	ITGA4	Integrin Subunit Alpha 4	Protein Coding	4
325	ITGA5	Integrin Subunit Alpha 5	Protein Coding	4
326	ITGA6	Integrin Subunit Alpha 6	Protein Coding	4
327	ITGA7	Integrin Subunit Alpha 7	Protein Coding	4
328	ITGA8	Integrin Subunit Alpha 8	Protein Coding	4
329	ITGA9	Integrin Subunit Alpha 9	Protein Coding	4
330	LTA	Lymphotoxin Alpha	Protein Coding	4
331	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	4
332	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	4
333	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	4
334	OSM	Oncostatin M	Protein Coding	4
335	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	4
336	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	4
337	CDC42	Cell Division Cycle 42	Protein Coding	4
338	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	4
339	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	4
340	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	4
341	ADCY1	Adenylate Cyclase 1	Protein Coding	3
342	ADCY2	Adenylate Cyclase 2	Protein Coding	3
343	ADCY3	Adenylate Cyclase 3	Protein Coding	3
344	ADCY4	Adenylate Cyclase 4	Protein Coding	3
345	ADCY5	Adenylate Cyclase 5	Protein Coding	3
346	ADCY6	Adenylate Cyclase 6	Protein Coding	3
347	ADCY7	Adenylate Cyclase 7	Protein Coding	3
348	ADCY8	Adenylate Cyclase 8	Protein Coding	3
349	ADCY9	Adenylate Cyclase 9	Protein Coding	3
350	ANGPT1	Angiopoietin 1	Protein Coding	3
351	ANGPT2	Angiopoietin 2	Protein Coding	3
352	ANGPT4	Angiopoietin 4	Protein Coding	3
353	ANGPTL1	Angiopoietin Like 1	Protein Coding	3
354	ATF1	Activating Transcription Factor 1	Protein Coding	3
355	ATF4	Activating Transcription Factor 4	Protein Coding	3
356	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	3
357	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	3
358	BMP15	Bone Morphogenetic Protein 15	Protein Coding	3
359	BMP8B	Bone Morphogenetic Protein 8b	Protein Coding	3
360	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	3
361	BTK	Bruton Tyrosine Kinase	Protein Coding	3
362	CCL1	C-C Motif Chemokine Ligand 1	Protein Coding	3
363	CCL11	C-C Motif Chemokine Ligand 11	Protein Coding	3
364	CCL13	C-C Motif Chemokine Ligand 13	Protein Coding	3
365	CCL14	C-C Motif Chemokine Ligand 14	Protein Coding	3
366	CCL15	C-C Motif Chemokine Ligand 15	Protein Coding	3
367	CCL16	C-C Motif Chemokine Ligand 16	Protein Coding	3
368	CCL17	C-C Motif Chemokine Ligand 17	Protein Coding	3
369	CCL18	C-C Motif Chemokine Ligand 18	Protein Coding	3
370	CCL19	C-C Motif Chemokine Ligand 19	Protein Coding	3
371	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	3
372	CCL20	C-C Motif Chemokine Ligand 20	Protein Coding	3
373	CCL21	C-C Motif Chemokine Ligand 21	Protein Coding	3
374	CCL22	C-C Motif Chemokine Ligand 22	Protein Coding	3
375	CCL23	C-C Motif Chemokine Ligand 23	Protein Coding	3
376	CCL24	C-C Motif Chemokine Ligand 24	Protein Coding	3
377	CCL25	C-C Motif Chemokine Ligand 25	Protein Coding	3
378	CCL26	C-C Motif Chemokine Ligand 26	Protein Coding	3
379	CCL27	C-C Motif Chemokine Ligand 27	Protein Coding	3
380	CCL28	C-C Motif Chemokine Ligand 28	Protein Coding	3
381	CCL3	C-C Motif Chemokine Ligand 3	Protein Coding	3
382	CCL3L1	C-C Motif Chemokine Ligand 3 Like 1	Protein Coding	3
383	CCL4	C-C Motif Chemokine Ligand 4	Protein Coding	3
384	CCL4L1	C-C Motif Chemokine Ligand 4 Like 1	Protein Coding	3
385	CCL4L2	C-C Motif Chemokine Ligand 4 Like 2	Protein Coding	3
386	CCL5	C-C Motif Chemokine Ligand 5	Protein Coding	3
387	CCL7	C-C Motif Chemokine Ligand 7	Protein Coding	3
388	CCL8	C-C Motif Chemokine Ligand 8	Protein Coding	3
389	CD2	CD2 Molecule	Protein Coding	3
390	CD80	CD80 Molecule	Protein Coding	3
391	CER1	Cerberus 1, DAN Family BMP Antagonist	Protein Coding	3
392	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	3
393	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	3
394	CREB3	CAMP Responsive Element Binding Protein 3	Protein Coding	3
395	CREB3L4	CAMP Responsive Element Binding Protein 3 Like 4	Protein Coding	3
396	CSF1	Colony Stimulating Factor 1	Protein Coding	3
397	CSF2	Colony Stimulating Factor 2	Protein Coding	3
398	CSF3	Colony Stimulating Factor 3	Protein Coding	3
399	CX3CL1	C-X3-C Motif Chemokine Ligand 1	Protein Coding	3
400	CXCL1	C-X-C Motif Chemokine Ligand 1	Protein Coding	3
401	CXCL10	C-X-C Motif Chemokine Ligand 10	Protein Coding	3
402	CXCL11	C-X-C Motif Chemokine Ligand 11	Protein Coding	3
403	CXCL13	C-X-C Motif Chemokine Ligand 13	Protein Coding	3
404	CXCL14	C-X-C Motif Chemokine Ligand 14	Protein Coding	3
405	CXCL16	C-X-C Motif Chemokine Ligand 16	Protein Coding	3
406	CXCL2	C-X-C Motif Chemokine Ligand 2	Protein Coding	3
407	CXCL3	C-X-C Motif Chemokine Ligand 3	Protein Coding	3
408	CXCL5	C-X-C Motif Chemokine Ligand 5	Protein Coding	3
409	CXCL6	C-X-C Motif Chemokine Ligand 6	Protein Coding	3
410	CXCL9	C-X-C Motif Chemokine Ligand 9	Protein Coding	3
411	DAP	Death Associated Protein	Protein Coding	3
412	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	3
413	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	3
414	IL10	Interleukin 10	Protein Coding	3
415	IL11	Interleukin 11	Protein Coding	3
416	IL12A	Interleukin 12A	Protein Coding	3
417	IL12B	Interleukin 12B	Protein Coding	3
418	IL13	Interleukin 13	Protein Coding	3
419	IL15	Interleukin 15	Protein Coding	3
420	IL16	Interleukin 16	Protein Coding	3
421	IL17A	Interleukin 17A	Protein Coding	3
422	IL18	Interleukin 18	Protein Coding	3
423	IL19	Interleukin 19	Protein Coding	3
424	IL20	Interleukin 20	Protein Coding	3
425	IL21	Interleukin 21	Protein Coding	3
426	IL22	Interleukin 22	Protein Coding	3
427	IL23A	Interleukin 23 Subunit Alpha	Protein Coding	3
428	IL24	Interleukin 24	Protein Coding	3
429	IL26	Interleukin 26	Protein Coding	3
430	IL4	Interleukin 4	Protein Coding	3
431	IL5	Interleukin 5	Protein Coding	3
432	IL7	Interleukin 7	Protein Coding	3
433	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	3
434	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	3
435	LIF	LIF Interleukin 6 Family Cytokine	Protein Coding	3
436	MRAS	Muscle RAS Oncogene Homolog	Protein Coding	3
437	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	3
438	PAK2	P21 (RAC1) Activated Kinase 2	Protein Coding	3
439	PAK3	P21 (RAC1) Activated Kinase 3	Protein Coding	3
440	PAK4	P21 (RAC1) Activated Kinase 4	Protein Coding	3
441	PAK6	P21 (RAC1) Activated Kinase 6	Protein Coding	3
442	PAK5	P21 (RAC1) Activated Kinase 5	Protein Coding	3
443	PF4	Platelet Factor 4	Protein Coding	3
444	PF4V1	Platelet Factor 4 Variant 1	Protein Coding	3
445	PIP	Prolactin Induced Protein	Protein Coding	3
446	PLCB1	Phospholipase C Beta 1	Protein Coding	3
447	PLCB2	Phospholipase C Beta 2	Protein Coding	3
448	PLCB3	Phospholipase C Beta 3	Protein Coding	3
449	PLCB4	Phospholipase C Beta 4	Protein Coding	3
450	PPBPP2	Pro-Platelet Basic Protein Pseudogene 2	Pseudogene	3
451	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	3
452	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	3
453	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	3
454	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	3
455	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	3
456	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	3
457	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	3
458	PRKCA	Protein Kinase C Alpha	Protein Coding	3
459	PRKCB	Protein Kinase C Beta	Protein Coding	3
460	PRKCD	Protein Kinase C Delta	Protein Coding	3
461	PRKCE	Protein Kinase C Epsilon	Protein Coding	3
462	PRKCG	Protein Kinase C Gamma	Protein Coding	3
463	PRKCH	Protein Kinase C Eta	Protein Coding	3
464	PRKCI	Protein Kinase C Iota	Protein Coding	3
465	PRKD1	Protein Kinase D1	Protein Coding	3
466	PRKD3	Protein Kinase D3	Protein Coding	3
467	PRKCQ	Protein Kinase C Theta	Protein Coding	3
468	PRKCZ	Protein Kinase C Zeta	Protein Coding	3
469	RAP1A	RAP1A, Member Of RAS Oncogene Family	Protein Coding	3
470	RAP1B	RAP1B, Member Of RAS Oncogene Family	Protein Coding	3
471	RPS6KA4	Ribosomal Protein S6 Kinase A4	Protein Coding	3
472	RPS6KA5	Ribosomal Protein S6 Kinase A5	Protein Coding	3
473	RRAS	RAS Related	Protein Coding	3
474	RRAS2	RAS Related 2	Protein Coding	3
475	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	3
476	SOS2	SOS Ras/Rho Guanine Nucleotide Exchange Factor 2	Protein Coding	3
477	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	3
478	TNFSF10	TNF Superfamily Member 10	Protein Coding	3
479	TNFSF11	TNF Superfamily Member 11	Protein Coding	3
480	TNFSF12	TNF Superfamily Member 12	Protein Coding	3
481	TNFSF13	TNF Superfamily Member 13	Protein Coding	3
482	TNFSF13B	TNF Superfamily Member 13b	Protein Coding	3
483	TNFSF14	TNF Superfamily Member 14	Protein Coding	3
484	TNFSF18	TNF Superfamily Member 18	Protein Coding	3
485	TNFSF4	TNF Superfamily Member 4	Protein Coding	3
486	CD40LG	CD40 Ligand	Protein Coding	3
487	FASLG	Fas Ligand	Protein Coding	3
488	CD70	CD70 Molecule	Protein Coding	3
489	TNFSF8	TNF Superfamily Member 8	Protein Coding	3
490	TNFSF9	TNF Superfamily Member 9	Protein Coding	3
491	TP53	Tumor Protein P53	Protein Coding	3
492	RHOA	Ras Homolog Family Member A	Protein Coding	3
493	RHOB	Ras Homolog Family Member B	Protein Coding	3
494	RHOC	Ras Homolog Family Member C	Protein Coding	3
495	RHOD	Ras Homolog Family Member D	Protein Coding	3
496	RND3	Rho Family GTPase 3	Protein Coding	3
497	RHOG	Ras Homolog Family Member G	Protein Coding	3
498	ARHGEF6	Rac/Cdc42 Guanine Nucleotide Exchange Factor 6	Protein Coding	3
499	RHOH	Ras Homolog Family Member H	Protein Coding	3
500	DIRAS3	DIRAS Family GTPase 3	Protein Coding	3
501	RND2	Rho Family GTPase 2	Protein Coding	3
502	CDH1	Cadherin 1	Protein Coding	3
503	MAP2K3	Mitogen-Activated Protein Kinase Kinase 3	Protein Coding	3
504	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	3
505	MAP2K7	Mitogen-Activated Protein Kinase Kinase 7	Protein Coding	3
506	RAC2	Rac Family Small GTPase 2	Protein Coding	3
507	RAC3	Rac Family Small GTPase 3	Protein Coding	3
508	TCF3	Transcription Factor 3	Protein Coding	3
509	TCF4	Transcription Factor 4	Protein Coding	3
510	TNFRSF1A	TNF Receptor Superfamily Member 1A	Protein Coding	3
511	ARAF	A-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	2
512	CNKSR1	Connector Enhancer Of Kinase Suppressor Of Ras 1	Protein Coding	2
513	ELK3	ETS Transcription Factor ELK3	Protein Coding	2
514	ELK4	ETS Transcription Factor ELK4	Protein Coding	2
515	LAMTOR3	Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 3	Protein Coding	2
516	MAX	MYC Associated Transcriptional Regulator X	Protein Coding	2
517	MKNK1	MAPK Interacting Serine/Threonine Kinase 1	Protein Coding	2
518	MKNK2	MAPK Interacting Serine/Threonine Kinase 2	Protein Coding	2
519	MYLK	Myosin Light Chain Kinase	Protein Coding	2
520	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	2
521	PLCG1	Phospholipase C Gamma 1	Protein Coding	2
522	PPP1R12A	Protein Phosphatase 1 Regulatory Subunit 12A	Protein Coding	2
523	PPP1R12B	Protein Phosphatase 1 Regulatory Subunit 12B	Protein Coding	2
524	PPP1R14B	Protein Phosphatase 1 Regulatory Inhibitor Subunit 14B	Protein Coding	2
525	PPP2CA	Protein Phosphatase 2 Catalytic Subunit Alpha	Protein Coding	2
526	PPP2CB	Protein Phosphatase 2 Catalytic Subunit Beta	Protein Coding	2
527	PPP2R1A	Protein Phosphatase 2 Scaffold Subunit Aalpha	Protein Coding	2
528	PPP2R1B	Protein Phosphatase 2 Scaffold Subunit Abeta	Protein Coding	2
529	PPP2R2A	Protein Phosphatase 2 Regulatory Subunit Balpha	Protein Coding	2
530	PPP2R2B	Protein Phosphatase 2 Regulatory Subunit Bbeta	Protein Coding	2
531	PPP2R2C	Protein Phosphatase 2 Regulatory Subunit Bgamma	Protein Coding	2
532	PPP2R3A	Protein Phosphatase 2 Regulatory Subunit B''''Alpha	Protein Coding	2
533	PTPA	Protein Phosphatase 2 Phosphatase Activator	Protein Coding	2
534	PPP2R5A	Protein Phosphatase 2 Regulatory Subunit B''Alpha	Protein Coding	2
535	PPP2R5B	Protein Phosphatase 2 Regulatory Subunit B''Beta	Protein Coding	2
536	PPP2R5C	Protein Phosphatase 2 Regulatory Subunit B''Gamma	Protein Coding	2
537	PPP2R5E	Protein Phosphatase 2 Regulatory Subunit B''Epsilon	Protein Coding	2
538	PPP2R3B	Protein Phosphatase 2 Regulatory Subunit B''''Beta~Name Same As:- HGNC:9310	Protein Coding	2
539	RPS6KA1	Ribosomal Protein S6 Kinase A1	Protein Coding	2
540	RPS6KA2	Ribosomal Protein S6 Kinase A2	Protein Coding	2
541	RPS6KA3	Ribosomal Protein S6 Kinase A3	Protein Coding	2
542	RPS6KA6	Ribosomal Protein S6 Kinase A6	Protein Coding	2
543	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	2
544	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	2
545	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	2
546	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	2
547	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	2
548	ARHGEF1	Rho Guanine Nucleotide Exchange Factor 1	Protein Coding	2
549	ARHGEF10	Rho Guanine Nucleotide Exchange Factor 10	Protein Coding	2
550	ARHGEF11	Rho Guanine Nucleotide Exchange Factor 11	Protein Coding	2
551	ARHGEF12	Rho Guanine Nucleotide Exchange Factor 12	Protein Coding	2
552	ARHGEF15	Rho Guanine Nucleotide Exchange Factor 15	Protein Coding	2
553	ARHGEF16	Rho Guanine Nucleotide Exchange Factor 16	Protein Coding	2
554	ARHGEF2	Rho/Rac Guanine Nucleotide Exchange Factor 2	Protein Coding	2
555	ARHGEF3	Rho Guanine Nucleotide Exchange Factor 3	Protein Coding	2
556	ARHGEF4	Rho Guanine Nucleotide Exchange Factor 4	Protein Coding	2
557	ARHGEF5	Rho Guanine Nucleotide Exchange Factor 5	Protein Coding	2
558	ARHGEF7	Rho Guanine Nucleotide Exchange Factor 7	Protein Coding	2
559	ARHGEF9	Cdc42 Guanine Nucleotide Exchange Factor 9	Protein Coding	2
560	CASP3	Caspase 3	Protein Coding	2
561	CASP9	Caspase 9	Protein Coding	2
562	CCND1	Cyclin D1	Protein Coding	2
563	CTNNB1	Catenin Beta 1	Protein Coding	2
564	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	2
565	GSK3A	Glycogen Synthase Kinase 3 Alpha	Protein Coding	2
566	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	2
567	HIF1A	Hypoxia Inducible Factor 1 Subunit Alpha	Protein Coding	2
568	IL1R1	Interleukin 1 Receptor Type 1	Protein Coding	2
569	IL2RA	Interleukin 2 Receptor Subunit Alpha	Protein Coding	2
570	IRS1	Insulin Receptor Substrate 1	Protein Coding	2
571	LEF1	Lymphoid Enhancer Binding Factor 1	Protein Coding	2
572	MAP3K5	Mitogen-Activated Protein Kinase Kinase Kinase 5	Protein Coding	2
573	MAP3K7	Mitogen-Activated Protein Kinase Kinase Kinase 7	Protein Coding	2
574	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	2
575	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	2
576	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	2
577	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	2
578	MAPK6	Mitogen-Activated Protein Kinase 6	Protein Coding	2
579	MAPK7	Mitogen-Activated Protein Kinase 7	Protein Coding	2
580	MCF2L	MCF.2 Cell Line Derived Transforming Sequence Like	Protein Coding	2
581	NET1	Neuroepithelial Cell Transforming 1	Protein Coding	2
582	NGFR	Nerve Growth Factor Receptor	Protein Coding	2
583	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	2
584	PTEN	Phosphatase And Tensin Homolog	Protein Coding	2
585	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	2
586	TNFRSF1B	TNF Receptor Superfamily Member 1B	Protein Coding	2
587	TRADD	TNFRSF1A Associated Via Death Domain	Protein Coding	2
588	CDH10	Cadherin 10	Protein Coding	2
589	CDH11	Cadherin 11	Protein Coding	2
590	CDH12	Cadherin 12	Protein Coding	2
591	CDH13	Cadherin 13	Protein Coding	2
592	CDH15	Cadherin 15	Protein Coding	2
593	CDH16	Cadherin 16	Protein Coding	2
594	CDH17	Cadherin 17	Protein Coding	2
595	CDH18	Cadherin 18	Protein Coding	2
596	CDH19	Cadherin 19	Protein Coding	2
597	CDH2	Cadherin 2	Protein Coding	2
598	CDH3	Cadherin 3	Protein Coding	2
599	CDH4	Cadherin 4	Protein Coding	2
600	CDH5	Cadherin 5	Protein Coding	2
601	CDH6	Cadherin 6	Protein Coding	2
602	CDH7	Cadherin 7	Protein Coding	2
603	CDH8	Cadherin 8	Protein Coding	2
604	CDH9	Cadherin 9	Protein Coding	2
605	CFL1	Cofilin 1	Protein Coding	2
606	CFL2	Cofilin 2	Protein Coding	2
607	MAP2K4	Mitogen-Activated Protein Kinase Kinase 4	Protein Coding	2
608	MAP2K5	Mitogen-Activated Protein Kinase Kinase 5	Protein Coding	2
609	MAP3K10	Mitogen-Activated Protein Kinase Kinase Kinase 10	Protein Coding	2
610	MAP3K11	Mitogen-Activated Protein Kinase Kinase Kinase 11	Protein Coding	2
611	MYL9	Myosin Light Chain 9	Protein Coding	2
612	VIM	Vimentin	Protein Coding	2
613	ATF2	Activating Transcription Factor 2	Protein Coding	2
614	ATF3	Activating Transcription Factor 3	Protein Coding	2
615	ATF5	Activating Transcription Factor 5	Protein Coding	2
616	ATF6	Activating Transcription Factor 6	Protein Coding	2
617	ATF7	Activating Transcription Factor 7	Protein Coding	2
618	BCAR1	BCAR1 Scaffold Protein, Cas Family Member	Protein Coding	2
619	GCFC2	GC-Rich Sequence DNA-Binding Factor 2	Protein Coding	2
620	CEBPB	CCAAT Enhancer Binding Protein Beta	Protein Coding	2
621	HNF4A	Hepatocyte Nuclear Factor 4 Alpha	Protein Coding	2
622	NFE2L1	NFE2 Like BZIP Transcription Factor 1	Protein Coding	2
623	PXN	Paxillin	Protein Coding	2
624	HNF1A	HNF1 Homeobox A	Protein Coding	2
625	TCF12	Transcription Factor 12	Protein Coding	2
626	TCF15	Transcription Factor 15	Protein Coding	2
627	TCF19	Transcription Factor 19	Protein Coding	2
628	HNF1B	HNF1 Homeobox B	Protein Coding	2
629	TCF20	Transcription Factor 20	Protein Coding	2
630	TCF21	Transcription Factor 21	Protein Coding	2
631	TCF23	Transcription Factor 23	Protein Coding	2
632	TCF7	Transcription Factor 7	Protein Coding	2
633	TCF7L2	Transcription Factor 7 Like 2	Protein Coding	2
634	ZEB1	Zinc Finger E-Box Binding Homeobox 1	Protein Coding	2
635	TEAD1	TEA Domain Transcription Factor 1	Protein Coding	2
636	TEAD4	TEA Domain Transcription Factor 4	Protein Coding	2
637	TFAM	Transcription Factor A, Mitochondrial	Protein Coding	2
638	ZNF354A	Zinc Finger Protein 354A	Protein Coding	2
639	BRF1	BRF1 General Transcription Factor IIIB Subunit	Protein Coding	1
640	CACNA1A	Calcium Voltage-Gated Channel Subunit Alpha1 A	Protein Coding	1
641	CACNA1B	Calcium Voltage-Gated Channel Subunit Alpha1 B	Protein Coding	1
642	CACNA1C	Calcium Voltage-Gated Channel Subunit Alpha1 C	Protein Coding	1
643	CACNA1D	Calcium Voltage-Gated Channel Subunit Alpha1 D	Protein Coding	1
644	CACNA1E	Calcium Voltage-Gated Channel Subunit Alpha1 E	Protein Coding	1
645	CACNA1F	Calcium Voltage-Gated Channel Subunit Alpha1 F	Protein Coding	1
646	CACNA1G	Calcium Voltage-Gated Channel Subunit Alpha1 G	Protein Coding	1
647	CACNA1H	Calcium Voltage-Gated Channel Subunit Alpha1 H	Protein Coding	1
648	CACNA1I	Calcium Voltage-Gated Channel Subunit Alpha1 I	Protein Coding	1
649	CACNA1S	Calcium Voltage-Gated Channel Subunit Alpha1 S	Protein Coding	1
650	CACNA2D1	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 1	Protein Coding	1
651	CACNA2D2	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 2	Protein Coding	1
652	CACNA2D3	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 3	Protein Coding	1
653	CACNA2D4	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 4	Protein Coding	1
654	CACNB1	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 1	Protein Coding	1
655	CACNB2	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 2	Protein Coding	1
656	CACNB3	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 3	Protein Coding	1
657	CACNB4	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 4	Protein Coding	1
658	CACNG1	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 1	Protein Coding	1
659	CACNG2	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 2	Protein Coding	1
660	CACNG3	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 3	Protein Coding	1
661	CACNG4	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 4	Protein Coding	1
662	CACNG5	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 5	Protein Coding	1
663	CACNG6	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 6	Protein Coding	1
664	CACNG7	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 7	Protein Coding	1
665	CACNG8	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 8	Protein Coding	1
666	CAPN1	Calpain 1	Protein Coding	1
667	CAPN10	Calpain 10	Protein Coding	1
668	CAPN11	Calpain 11	Protein Coding	1
669	CAPN2	Calpain 2	Protein Coding	1
670	CAPN3	Calpain 3	Protein Coding	1
671	CAPN5	Calpain 5	Protein Coding	1
672	CAPN6	Calpain 6	Protein Coding	1
673	CAPN7	Calpain 7	Protein Coding	1
674	CAPN9	Calpain 9	Protein Coding	1
675	CAPNS1	Calpain Small Subunit 1	Protein Coding	1
676	CD3D	CD3 Delta Subunit Of T-Cell Receptor Complex	Protein Coding	1
677	CD3E	CD3 Epsilon Subunit Of T-Cell Receptor Complex	Protein Coding	1
678	CD3G	CD3 Gamma Subunit Of T-Cell Receptor Complex	Protein Coding	1
679	CD247	CD247 Molecule	Protein Coding	1
680	DUSP1	Dual Specificity Phosphatase 1	Protein Coding	1
681	DUSP3	Dual Specificity Phosphatase 3	Protein Coding	1
682	ESR1	Estrogen Receptor 1	Protein Coding	1
683	ESR2	Estrogen Receptor 2	Protein Coding	1
684	ETS1	ETS Proto-Oncogene 1, Transcription Factor	Protein Coding	1
685	ETS2	ETS Proto-Oncogene 2, Transcription Factor	Protein Coding	1
686	H3-3A	H3.3 Histone A	Protein Coding	1
687	H3-3B	H3.3 Histone B	Protein Coding	1
688	H3C1	H3 Clustered Histone 1	Protein Coding	1
689	H3C2	H3 Clustered Histone 2	Protein Coding	1
690	H3C3	H3 Clustered Histone 3	Protein Coding	1
691	H3C4	H3 Clustered Histone 4	Protein Coding	1
692	H3C6	H3 Clustered Histone 6	Protein Coding	1
693	H3C7	H3 Clustered Histone 7	Protein Coding	1
694	H3C8	H3 Clustered Histone 8	Protein Coding	1
695	H3C10	H3 Clustered Histone 10	Protein Coding	1
696	H3C11	H3 Clustered Histone 11	Protein Coding	1
697	H3C12	H3 Clustered Histone 12	Protein Coding	1
698	H3-4	H3.4 Histone, Cluster Member	Protein Coding	1
699	HMGN1	High Mobility Group Nucleosome Binding Domain 1	Protein Coding	1
700	LAT	Linker For Activation Of T Cells	Protein Coding	1
701	PAX6	Paired Box 6	Protein Coding	1
702	PPP1R10	Protein Phosphatase 1 Regulatory Subunit 10	Protein Coding	1
703	PPP1R11	Protein Phosphatase 1 Regulatory Inhibitor Subunit 11	Protein Coding	1
704	PPP1R12C	Protein Phosphatase 1 Regulatory Subunit 12C	Protein Coding	1
705	PPP1R13B	Protein Phosphatase 1 Regulatory Subunit 13B	Protein Coding	1
706	PPP1R14A	Protein Phosphatase 1 Regulatory Inhibitor Subunit 14A	Protein Coding	1
707	PPP1R15A	Protein Phosphatase 1 Regulatory Subunit 15A	Protein Coding	1
708	PPP1R16A	Protein Phosphatase 1 Regulatory Subunit 16A	Protein Coding	1
709	PPP1R1A	Protein Phosphatase 1 Regulatory Inhibitor Subunit 1A	Protein Coding	1
710	PPP1R1B	Protein Phosphatase 1 Regulatory Inhibitor Subunit 1B	Protein Coding	1
711	PPP1R2	Protein Phosphatase 1 Regulatory Inhibitor Subunit 2	Protein Coding	1
712	PPP1R3A	Protein Phosphatase 1 Regulatory Subunit 3A	Protein Coding	1
713	PPP1R3B	Protein Phosphatase 1 Regulatory Subunit 3B	Protein Coding	1
714	PPP1R3C	Protein Phosphatase 1 Regulatory Subunit 3C	Protein Coding	1
715	PPP1R3D	Protein Phosphatase 1 Regulatory Subunit 3D	Protein Coding	1
716	PPP1R3F	Protein Phosphatase 1 Regulatory Subunit 3F	Protein Coding	1
717	PPP1R7	Protein Phosphatase 1 Regulatory Subunit 7	Protein Coding	1
718	PPP1R8	Protein Phosphatase 1 Regulatory Subunit 8	Protein Coding	1
719	PPP1R9A	Protein Phosphatase 1 Regulatory Subunit 9A	Protein Coding	1
720	PPP1R9B	Protein Phosphatase 1 Regulatory Subunit 9B	Protein Coding	1
721	SRF	Serum Response Factor	Protein Coding	1
722	TP53BP2	Tumor Protein P53 Binding Protein 2	Protein Coding	1
723	UBTF	Upstream Binding Transcription Factor	Protein Coding	1
724	ZAP70	Zeta Chain Of T Cell Receptor Associated Protein Kinase 70	Protein Coding	1
725	ABL1	ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase	Protein Coding	1
726	ABL2	ABL Proto-Oncogene 2, Non-Receptor Tyrosine Kinase	Protein Coding	1
727	ACVR1	Activin A Receptor Type 1	Protein Coding	1
728	ACVR2B	Activin A Receptor Type 2B	Protein Coding	1
729	ACVRL1	Activin A Receptor Like Type 1	Protein Coding	1
730	ADAM17	ADAM Metallopeptidase Domain 17	Protein Coding	1
731	APAF1	Apoptotic Peptidase Activating Factor 1	Protein Coding	1
732	APC	APC Regulator Of Wnt Signaling Pathway	Protein Coding	1
733	APH1A	Aph-1A Gamma-Secretase Subunit	Protein Coding	1
734	ATM	ATM Serine/Threonine Kinase	Protein Coding	1
735	ATR	ATR Checkpoint Kinase	Protein Coding	1
736	AURKB	Aurora Kinase B	Protein Coding	1
737	AURKC	Aurora Kinase C	Protein Coding	1
738	AXIN1	Axin 1	Protein Coding	1
739	BAK1	BCL2 Antagonist/Killer 1	Protein Coding	1
740	BBC3	BCL2 Binding Component 3	Protein Coding	1
741	BCL2L1	BCL2 Like 1	Protein Coding	1
742	BCL2L11	BCL2 Like 11	Protein Coding	1
743	BID	BH3 Interacting Domain Death Agonist	Protein Coding	1
744	BIRC2	Baculoviral IAP Repeat Containing 2	Protein Coding	1
745	BIRC3	Baculoviral IAP Repeat Containing 3	Protein Coding	1
746	CXCR5	C-X-C Motif Chemokine Receptor 5	Protein Coding	1
747	BMPR1A	Bone Morphogenetic Protein Receptor Type 1A	Protein Coding	1
748	BMPR1B	Bone Morphogenetic Protein Receptor Type 1B	Protein Coding	1
749	BMPR2	Bone Morphogenetic Protein Receptor Type 2	Protein Coding	1
750	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	1
751	CAMK2A	Calcium/Calmodulin Dependent Protein Kinase II Alpha	Protein Coding	1
752	CAMK2B	Calcium/Calmodulin Dependent Protein Kinase II Beta	Protein Coding	1
753	CAMK2D	Calcium/Calmodulin Dependent Protein Kinase II Delta	Protein Coding	1
754	CAMK2G	Calcium/Calmodulin Dependent Protein Kinase II Gamma	Protein Coding	1
755	CASP10	Caspase 10	Protein Coding	1
756	CASP6	Caspase 6	Protein Coding	1
757	CASP7	Caspase 7	Protein Coding	1
758	CASP8	Caspase 8	Protein Coding	1
759	CBL	Cbl Proto-Oncogene	Protein Coding	1
760	CCND2	Cyclin D2	Protein Coding	1
761	CCND3	Cyclin D3	Protein Coding	1
762	CCNE1	Cyclin E1	Protein Coding	1
763	CCNE2	Cyclin E2	Protein Coding	1
764	CCR1	C-C Motif Chemokine Receptor 1	Protein Coding	1
765	CCR2	C-C Motif Chemokine Receptor 2	Protein Coding	1
766	CCR3	C-C Motif Chemokine Receptor 3	Protein Coding	1
767	CCR4	C-C Motif Chemokine Receptor 4	Protein Coding	1
768	CCR5	C-C Motif Chemokine Receptor 5	Protein Coding	1
769	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	1
770	CCR7	C-C Motif Chemokine Receptor 7	Protein Coding	1
771	CCR8	C-C Motif Chemokine Receptor 8	Protein Coding	1
772	CCR9	C-C Motif Chemokine Receptor 9	Protein Coding	1
773	CCRL2	C-C Motif Chemokine Receptor Like 2	Protein Coding	1
774	CD28	CD28 Molecule	Protein Coding	1
775	CD4	CD4 Molecule	Protein Coding	1
776	CDK1	Cyclin Dependent Kinase 1	Protein Coding	1
777	CDC25A	Cell Division Cycle 25A	Protein Coding	1
778	CDC25B	Cell Division Cycle 25B	Protein Coding	1
779	CDC25C	Cell Division Cycle 25C	Protein Coding	1
780	CDK2	Cyclin Dependent Kinase 2	Protein Coding	1
781	CDK4	Cyclin Dependent Kinase 4	Protein Coding	1
782	CDK6	Cyclin Dependent Kinase 6	Protein Coding	1
783	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
784	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	1
785	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	1
786	CDKN2B	Cyclin Dependent Kinase Inhibitor 2B	Protein Coding	1
787	CDKN2C	Cyclin Dependent Kinase Inhibitor 2C	Protein Coding	1
788	CDKN2D	Cyclin Dependent Kinase Inhibitor 2D	Protein Coding	1
789	CFLAR	CASP8 And FADD Like Apoptosis Regulator	Protein Coding	1
790	CHEK1	Checkpoint Kinase 1	Protein Coding	1
791	CHEK2	Checkpoint Kinase 2	Protein Coding	1
792	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
793	CRK	CRK Proto-Oncogene, Adaptor Protein	Protein Coding	1
794	CSF2RA	Colony Stimulating Factor 2 Receptor Subunit Alpha	Protein Coding	1
795	CSF2RB	Colony Stimulating Factor 2 Receptor Subunit Beta	Protein Coding	1
796	CSF3R	Colony Stimulating Factor 3 Receptor	Protein Coding	1
797	CTNNA1	Catenin Alpha 1	Protein Coding	1
798	CTNNA2	Catenin Alpha 2	Protein Coding	1
799	CTNNA3	Catenin Alpha 3	Protein Coding	1
800	CTNND1	Catenin Delta 1	Protein Coding	1
801	CX3CR1	C-X3-C Motif Chemokine Receptor 1	Protein Coding	1
802	CXCR3	C-X-C Motif Chemokine Receptor 3	Protein Coding	1
803	CXCR4	C-X-C Motif Chemokine Receptor 4	Protein Coding	1
804	CXCR6	C-X-C Motif Chemokine Receptor 6	Protein Coding	1
805	CYCS	Cytochrome C, Somatic	Protein Coding	1
806	DHH	Desert Hedgehog Signaling Molecule	Protein Coding	1
807	DVL1	Dishevelled Segment Polarity Protein 1	Protein Coding	1
808	E2F1	E2F Transcription Factor 1	Protein Coding	1
809	E2F2	E2F Transcription Factor 2	Protein Coding	1
810	E2F3	E2F Transcription Factor 3	Protein Coding	1
811	E2F4	E2F Transcription Factor 4	Protein Coding	1
812	E2F5	E2F Transcription Factor 5	Protein Coding	1
813	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
814	FADD	Fas Associated Via Death Domain	Protein Coding	1
815	FANCD2	FA Complementation Group D2	Protein Coding	1
816	FOXO1	Forkhead Box O1	Protein Coding	1
817	FPR2	Formyl Peptide Receptor 2	Protein Coding	1
818	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
819	FZD1	Frizzled Class Receptor 1	Protein Coding	1
820	FZD10	Frizzled Class Receptor 10	Protein Coding	1
821	FZD2	Frizzled Class Receptor 2	Protein Coding	1
822	FZD3	Frizzled Class Receptor 3	Protein Coding	1
823	FZD4	Frizzled Class Receptor 4	Protein Coding	1
824	FZD5	Frizzled Class Receptor 5	Protein Coding	1
825	FZD6	Frizzled Class Receptor 6	Protein Coding	1
826	FZD7	Frizzled Class Receptor 7	Protein Coding	1
827	FZD8	Frizzled Class Receptor 8	Protein Coding	1
828	FZD9	Frizzled Class Receptor 9	Protein Coding	1
829	GAB1	GRB2 Associated Binding Protein 1	Protein Coding	1
830	GAB2	GRB2 Associated Binding Protein 2	Protein Coding	1
831	GLI1	GLI Family Zinc Finger 1	Protein Coding	1
832	GNB1L	G Protein Subunit Beta 1 Like	Protein Coding	1
833	RACK1	Receptor For Activated C Kinase 1	Protein Coding	1
834	CCR10	C-C Motif Chemokine Receptor 10	Protein Coding	1
835	HAT1	Histone Acetyltransferase 1	Protein Coding	1
836	HIPK2	Homeodomain Interacting Protein Kinase 2	Protein Coding	1
837	HRH4	Histamine Receptor H4	Protein Coding	1
838	IHH	Indian Hedgehog Signaling Molecule	Protein Coding	1
839	IL10RA	Interleukin 10 Receptor Subunit Alpha	Protein Coding	1
840	IL10RB	Interleukin 10 Receptor Subunit Beta	Protein Coding	1
841	IL11RA	Interleukin 11 Receptor Subunit Alpha	Protein Coding	1
842	IL12RB1	Interleukin 12 Receptor Subunit Beta 1	Protein Coding	1
843	IL12RB2	Interleukin 12 Receptor Subunit Beta 2	Protein Coding	1
844	IL13RA1	Interleukin 13 Receptor Subunit Alpha 1	Protein Coding	1
845	IL13RA2	Interleukin 13 Receptor Subunit Alpha 2	Protein Coding	1
846	IL15RA	Interleukin 15 Receptor Subunit Alpha	Protein Coding	1
847	IL17RA	Interleukin 17 Receptor A	Protein Coding	1
848	IL17RC	Interleukin 17 Receptor C	Protein Coding	1
849	IL18R1	Interleukin 18 Receptor 1	Protein Coding	1
850	IL20RA	Interleukin 20 Receptor Subunit Alpha	Protein Coding	1
851	IL22RA1	Interleukin 22 Receptor Subunit Alpha 1	Protein Coding	1
852	IL23R	Interleukin 23 Receptor	Protein Coding	1
853	IL2RB	Interleukin 2 Receptor Subunit Beta	Protein Coding	1
854	IL2RG	Interleukin 2 Receptor Subunit Gamma	Protein Coding	1
855	IL3RA	Interleukin 3 Receptor Subunit Alpha	Protein Coding	1
856	IL4R	Interleukin 4 Receptor	Protein Coding	1
857	IL5RA	Interleukin 5 Receptor Subunit Alpha	Protein Coding	1
858	IL6R	Interleukin 6 Receptor	Protein Coding	1
859	IL7R	Interleukin 7 Receptor	Protein Coding	1
860	CXCR1	C-X-C Motif Chemokine Receptor 1	Protein Coding	1
861	CXCR2	C-X-C Motif Chemokine Receptor 2	Protein Coding	1
862	IL9R	Interleukin 9 Receptor	Protein Coding	1
863	JAK1	Janus Kinase 1	Protein Coding	1
864	JAK2	Janus Kinase 2	Protein Coding	1
865	JAK3	Janus Kinase 3	Protein Coding	1
866	LRP5	LDL Receptor Related Protein 5	Protein Coding	1
867	LRP6	LDL Receptor Related Protein 6	Protein Coding	1
868	SMAD1	SMAD Family Member 1	Protein Coding	1
869	SMAD2	SMAD Family Member 2	Protein Coding	1
870	SMAD3	SMAD Family Member 3	Protein Coding	1
871	SMAD4	SMAD Family Member 4	Protein Coding	1
872	SMAD5	SMAD Family Member 5	Protein Coding	1
873	SMAD9	SMAD Family Member 9	Protein Coding	1
874	TAB1	TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 1	Protein Coding	1
875	TAB2	TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 2	Protein Coding	1
876	MDM2	MDM2 Proto-Oncogene	Protein Coding	1
877	TUBB6	Tubulin Beta 6 Class V	Protein Coding	1
878	TUBB2B	Tubulin Beta 2B Class IIb	Protein Coding	1
879	NBN	Nibrin	Protein Coding	1
880	NCSTN	Nicastrin	Protein Coding	1
881	NF1	Neurofibromin 1	Protein Coding	1
882	NFKBIB	NFKB Inhibitor Beta	Protein Coding	1
883	NFKBIE	NFKB Inhibitor Epsilon	Protein Coding	1
884	NLK	Nemo Like Kinase	Protein Coding	1
885	NOTCH1	Notch Receptor 1	Protein Coding	1
886	NOTCH2	Notch Receptor 2	Protein Coding	1
887	NOTCH3	Notch Receptor 3	Protein Coding	1
888	NOTCH4	Notch Receptor 4	Protein Coding	1
889	NUMB	NUMB Endocytic Adaptor Protein	Protein Coding	1
890	OSMR	Oncostatin M Receptor	Protein Coding	1
891	PSENEN	Presenilin Enhancer, Gamma-Secretase Subunit	Protein Coding	1
892	PIK3C2G	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Gamma	Protein Coding	1
893	PIK3CG	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma	Protein Coding	1
894	PMAIP1	Phorbol-12-Myristate-13-Acetate-Induced Protein 1	Protein Coding	1
895	PRKAA1	Protein Kinase AMP-Activated Catalytic Subunit Alpha 1	Protein Coding	1
896	PRKAA2	Protein Kinase AMP-Activated Catalytic Subunit Alpha 2	Protein Coding	1
897	PRKAB1	Protein Kinase AMP-Activated Non-Catalytic Subunit Beta 1	Protein Coding	1
898	PRKAB2	Protein Kinase AMP-Activated Non-Catalytic Subunit Beta 2	Protein Coding	1
899	PRKAG1	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 1	Protein Coding	1
900	PRKAG2	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 2	Protein Coding	1
901	PRKAG3	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 3	Protein Coding	1
902	PRKDC	Protein Kinase, DNA-Activated, Catalytic Subunit	Protein Coding	1
903	PSEN1	Presenilin 1	Protein Coding	1
904	PSEN2	Presenilin 2	Protein Coding	1
905	APH1B	Aph-1B Gamma-Secretase Subunit	Protein Coding	1
906	PTCH1	Patched 1	Protein Coding	1
907	PTCH2	Patched 2	Protein Coding	1
908	RAD51	RAD51 Recombinase	Protein Coding	1
909	RALA	RAS Like Proto-Oncogene A	Protein Coding	1
910	RALB	RAS Like Proto-Oncogene B	Protein Coding	1
911	RALBP1	RalA Binding Protein 1	Protein Coding	1
912	RALGDS	Ral Guanine Nucleotide Dissociation Stimulator	Protein Coding	1
913	RAP2A	RAP2A, Member Of RAS Oncogene Family	Protein Coding	1
914	RAP2B	RAP2B, Member Of RAS Oncogene Family	Protein Coding	1
915	RAP2C	RAP2C, Member Of RAS Oncogene Family	Protein Coding	1
916	RAPGEF1	Rap Guanine Nucleotide Exchange Factor 1	Protein Coding	1
917	RPTOR	Regulatory Associated Protein Of MTOR Complex 1	Protein Coding	1
918	RARA	Retinoic Acid Receptor Alpha	Protein Coding	1
919	RARB	Retinoic Acid Receptor Beta	Protein Coding	1
920	RARG	Retinoic Acid Receptor Gamma	Protein Coding	1
921	RASA1	RAS P21 Protein Activator 1	Protein Coding	1
922	RASGRF1	Ras Protein Specific Guanine Nucleotide Releasing Factor 1	Protein Coding	1
923	RASGRF2	Ras Protein Specific Guanine Nucleotide Releasing Factor 2	Protein Coding	1
924	RASGRP1	RAS Guanyl Releasing Protein 1	Protein Coding	1
925	RASGRP2	RAS Guanyl Releasing Protein 2	Protein Coding	1
926	RB1	RB Transcriptional Corepressor 1	Protein Coding	1
927	RBL1	RB Transcriptional Corepressor Like 1	Protein Coding	1
928	RBPJ	Recombination Signal Binding Protein For Immunoglobulin Kappa J Region	Protein Coding	1
929	RHEB	Ras Homolog, MTORC1 Binding	Protein Coding	1
930	NPTN	Neuroplastin	Protein Coding	1
931	DIABLO	Diablo IAP-Binding Mitochondrial Protein	Protein Coding	1
932	SMO	Smoothened, Frizzled Class Receptor	Protein Coding	1
933	SOX1	SRY-Box Transcription Factor 1	Protein Coding	1
934	SOX10	SRY-Box Transcription Factor 10	Protein Coding	1
935	SOX11	SRY-Box Transcription Factor 11	Protein Coding	1
936	SOX12	SRY-Box Transcription Factor 12	Protein Coding	1
937	SOX13	SRY-Box Transcription Factor 13	Protein Coding	1
938	SOX14	SRY-Box Transcription Factor 14	Protein Coding	1
939	SOX15	SRY-Box Transcription Factor 15	Protein Coding	1
940	SOX17	SRY-Box Transcription Factor 17	Protein Coding	1
941	SOX18	SRY-Box Transcription Factor 18	Protein Coding	1
942	SOX2	SRY-Box Transcription Factor 2	Protein Coding	1
943	SOX21	SRY-Box Transcription Factor 21	Protein Coding	1
944	SOX3	SRY-Box Transcription Factor 3	Protein Coding	1
945	SOX30	SRY-Box Transcription Factor 30	Protein Coding	1
946	SOX4	SRY-Box Transcription Factor 4	Protein Coding	1
947	SOX5	SRY-Box Transcription Factor 5	Protein Coding	1
948	SOX6	SRY-Box Transcription Factor 6	Protein Coding	1
949	SOX7	SRY-Box Transcription Factor 7	Protein Coding	1
950	SOX8	SRY-Box Transcription Factor 8	Protein Coding	1
951	SOX9	SRY-Box Transcription Factor 9	Protein Coding	1
952	STK11	Serine/Threonine Kinase 11	Protein Coding	1
953	STK36	Serine/Threonine Kinase 36	Protein Coding	1
954	AURKA	Aurora Kinase A	Protein Coding	1
955	SUFU	SUFU Negative Regulator Of Hedgehog Signaling	Protein Coding	1
956	SYNGAP1	Synaptic Ras GTPase Activating Protein 1	Protein Coding	1
957	TGFBR2	Transforming Growth Factor Beta Receptor 2	Protein Coding	1
958	TNFAIP6	TNF Alpha Induced Protein 6	Protein Coding	1
959	TNFRSF10A	TNF Receptor Superfamily Member 10a	Protein Coding	1
960	TNFRSF10B	TNF Receptor Superfamily Member 10b	Protein Coding	1
961	TNFRSF10C	TNF Receptor Superfamily Member 10c	Protein Coding	1
962	TNFRSF10D	TNF Receptor Superfamily Member 10d	Protein Coding	1
963	TNFRSF11A	TNF Receptor Superfamily Member 11a	Protein Coding	1
964	TNFRSF25	TNF Receptor Superfamily Member 25	Protein Coding	1
965	TNFRSF12A	TNF Receptor Superfamily Member 12A	Protein Coding	1
966	TNFRSF13B	TNF Receptor Superfamily Member 13B	Protein Coding	1
967	TNFRSF13C	TNF Receptor Superfamily Member 13C	Protein Coding	1
968	TNFRSF14	TNF Receptor Superfamily Member 14	Protein Coding	1
969	TNFRSF17	TNF Receptor Superfamily Member 17	Protein Coding	1
970	TNFRSF18	TNF Receptor Superfamily Member 18	Protein Coding	1
971	TNFRSF21	TNF Receptor Superfamily Member 21	Protein Coding	1
972	TNFRSF4	TNF Receptor Superfamily Member 4	Protein Coding	1
973	CD40	CD40 Molecule	Protein Coding	1
974	FAS	Fas Cell Surface Death Receptor	Protein Coding	1
975	TNFRSF6B	TNF Receptor Superfamily Member 6b	Protein Coding	1
976	CD27	CD27 Molecule	Protein Coding	1
977	TNFRSF8	TNF Receptor Superfamily Member 8	Protein Coding	1
978	TNFRSF9	TNF Receptor Superfamily Member 9	Protein Coding	1
979	TSC1	TSC Complex Subunit 1	Protein Coding	1
980	TSC2	TSC Complex Subunit 2	Protein Coding	1
981	TUBA4A	Tubulin Alpha 4a	Protein Coding	1
982	TUBA3C	Tubulin Alpha 3c	Protein Coding	1
983	TUBA8	Tubulin Alpha 8	Protein Coding	1
984	TUBB1	Tubulin Beta 1 Class VI	Protein Coding	1
985	TUBB2A	Tubulin Beta 2A Class IIa	Protein Coding	1
986	TUBB3	Tubulin Beta 3 Class III	Protein Coding	1
987	TUBB7P	Tubulin Beta 7 Pseudogene	Pseudogene	1
988	TUBD1	Tubulin Delta 1	Protein Coding	1
989	TUBE1	Tubulin Epsilon 1	Protein Coding	1
990	TUBG1	Tubulin Gamma 1	Protein Coding	1
991	TUBG2	Tubulin Gamma 2	Protein Coding	1
992	VHL	Von Hippel-Lindau Tumor Suppressor	Protein Coding	1
993	WEE1	WEE1 G2 Checkpoint Kinase	Protein Coding	1
994	WNT1	Wnt Family Member 1	Protein Coding	1
995	WNT5A	Wnt Family Member 5A	Protein Coding	1
996	XCR1	X-C Motif Chemokine Receptor 1	Protein Coding	1
997	ACTR2	Actin Related Protein 2	Protein Coding	1
998	ACTR3	Actin Related Protein 3	Protein Coding	1
999	ARFIP2	ARF Interacting Protein 2	Protein Coding	1
1000	ARHGDIA	Rho GDP Dissociation Inhibitor Alpha	Protein Coding	1
1001	ARHGDIB	Rho GDP Dissociation Inhibitor Beta	Protein Coding	1
1002	BAIAP2	BAR/IMD Domain Containing Adaptor Protein 2	Protein Coding	1
1003	SEPTIN7	Septin 7	Protein Coding	1
1004	CDC42EP1	CDC42 Effector Protein 1	Protein Coding	1
1005	CDC42EP2	CDC42 Effector Protein 2	Protein Coding	1
1006	CDC42EP3	CDC42 Effector Protein 3	Protein Coding	1
1007	CDC42EP4	CDC42 Effector Protein 4	Protein Coding	1
1008	CDC42EP5	CDC42 Effector Protein 5	Protein Coding	1
1009	CIT	Citron Rho-Interacting Serine/Threonine Kinase	Protein Coding	1
1010	CYFIP1	Cytoplasmic FMR1 Interacting Protein 1	Protein Coding	1
1011	DES	Desmin	Protein Coding	1
1012	DIAPH3	Diaphanous Related Formin 3	Protein Coding	1
1013	SEPTIN11	Septin 11	Protein Coding	1
1014	GFAP	Glial Fibrillary Acidic Protein	Protein Coding	1
1015	IQGAP1	IQ Motif Containing GTPase Activating Protein 1	Protein Coding	1
1016	LIMK1	LIM Domain Kinase 1	Protein Coding	1
1017	LIMK2	LIM Domain Kinase 2	Protein Coding	1
1018	MAP3K9	Mitogen-Activated Protein Kinase Kinase Kinase 9	Protein Coding	1
1019	SEPTIN9	Septin 9	Protein Coding	1
1020	MSN	Moesin	Protein Coding	1
1021	NCF2	Neutrophil Cytosolic Factor 2	Protein Coding	1
1022	SEPTIN2	Septin 2	Protein Coding	1
1023	PARD3	Par-3 Family Cell Polarity Regulator	Protein Coding	1
1024	PARD6A	Par-6 Family Cell Polarity Regulator Alpha	Protein Coding	1
1025	PIP5K1A	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Alpha	Protein Coding	1
1026	PIP5K1B	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Beta	Protein Coding	1
1027	PIP5K1C	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Gamma	Protein Coding	1
1028	PIP4K2A	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Alpha	Protein Coding	1
1029	PIP4K2B	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Beta	Protein Coding	1
1030	PIP4K2C	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Gamma	Protein Coding	1
1031	PLD1	Phospholipase D1	Protein Coding	1
1032	SEPTIN5	Septin 5	Protein Coding	1
1033	SEPTIN4	Septin 4	Protein Coding	1
1034	PKN1	Protein Kinase N1	Protein Coding	1
1035	RDX	Radixin	Protein Coding	1
1036	ROCK1	Rho Associated Coiled-Coil Containing Protein Kinase 1	Protein Coding	1
1037	ROCK2	Rho Associated Coiled-Coil Containing Protein Kinase 2	Protein Coding	1
1038	CLIP1	CAP-Gly Domain Containing Linker Protein 1	Protein Coding	1
1039	SLC9A1	Solute Carrier Family 9 Member A1	Protein Coding	1
1040	STMN1	Stathmin 1	Protein Coding	1
1041	EZR	Ezrin	Protein Coding	1
1042	WASF1	WASP Family Member 1	Protein Coding	1
1043	WASF3	WASP Family Member 3	Protein Coding	1
1044	WASL	WASP Like Actin Nucleation Promoting Factor	Protein Coding	1
1045	WIPF1	WAS/WASL Interacting Protein Family Member 1	Protein Coding	1
1046	CLEC14A	C-Type Lectin Domain Containing 14A	Protein Coding	1
1047	DDIT3	DNA Damage Inducible Transcript 3	Protein Coding	1
1048	HBEGF	Heparin Binding EGF Like Growth Factor	Protein Coding	1
1049	GLG1	Golgi Glycoprotein 1	Protein Coding	1
1050	HSF1	Heat Shock Transcription Factor 1	Protein Coding	1
1051	IGF2R	Insulin Like Growth Factor 2 Receptor	Protein Coding	1
1052	IL1R2	Interleukin 1 Receptor Type 2	Protein Coding	1
1053	IRAK1	Interleukin 1 Receptor Associated Kinase 1	Protein Coding	1
1054	IRAK2	Interleukin 1 Receptor Associated Kinase 2	Protein Coding	1
1055	IRAK3	Interleukin 1 Receptor Associated Kinase 3	Protein Coding	1
1056	IRAK4	Interleukin 1 Receptor Associated Kinase 4	Protein Coding	1
1057	MAP3K2	Mitogen-Activated Protein Kinase Kinase Kinase 2	Protein Coding	1
1058	MAP3K3	Mitogen-Activated Protein Kinase Kinase Kinase 3	Protein Coding	1
1059	MAP3K4	Mitogen-Activated Protein Kinase Kinase Kinase 4	Protein Coding	1
1060	MAP3K8	Mitogen-Activated Protein Kinase Kinase Kinase 8	Protein Coding	1
1061	MAPK8IP1	Mitogen-Activated Protein Kinase 8 Interacting Protein 1	Protein Coding	1
1062	MAPK8IP2	Mitogen-Activated Protein Kinase 8 Interacting Protein 2	Protein Coding	1
1063	MAPK8IP3	Mitogen-Activated Protein Kinase 8 Interacting Protein 3	Protein Coding	1
1064	MAPKAPK2	MAPK Activated Protein Kinase 2	Protein Coding	1
1065	MEF2A	Myocyte Enhancer Factor 2A	Protein Coding	1
1066	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	1
1067	MEF2D	Myocyte Enhancer Factor 2D	Protein Coding	1
1068	NRP1	Neuropilin 1	Protein Coding	1
1069	NRP2	Neuropilin 2	Protein Coding	1
1070	OGFR	Opioid Growth Factor Receptor	Protein Coding	1
1071	PLCD1	Phospholipase C Delta 1	Protein Coding	1
1072	PLCD3	Phospholipase C Delta 3	Protein Coding	1
1073	PLCD4	Phospholipase C Delta 4	Protein Coding	1
1074	PLCE1	Phospholipase C Epsilon 1	Protein Coding	1
1075	PLCG2	Phospholipase C Gamma 2	Protein Coding	1
1076	PLCZ1	Phospholipase C Zeta 1	Protein Coding	1
1077	WNK1	WNK Lysine Deficient Protein Kinase 1	Protein Coding	1
1078	RIPK1	Receptor Interacting Serine/Threonine Kinase 1	Protein Coding	1
1079	SH3RF1	SH3 Domain Containing Ring Finger 1	Protein Coding	1
1080	STAT2	Signal Transducer And Activator Of Transcription 2	Protein Coding	1
1081	STAT4	Signal Transducer And Activator Of Transcription 4	Protein Coding	1
1082	STAT5A	Signal Transducer And Activator Of Transcription 5A	Protein Coding	1
1083	STAT5B	Signal Transducer And Activator Of Transcription 5B	Protein Coding	1
1084	STAT6	Signal Transducer And Activator Of Transcription 6	Protein Coding	1
1085	TGFBR3	Transforming Growth Factor Beta Receptor 3	Protein Coding	1
1086	TLN1	Talin 1	Protein Coding	1
1087	TLN2	Talin 2	Protein Coding	1
1088	TRAF2	TNF Receptor Associated Factor 2	Protein Coding	1
1089	TRAF6	TNF Receptor Associated Factor 6	Protein Coding	1
1090	VCL	Vinculin	Protein Coding	1
1091	ACTA1	Actin Alpha 1, Skeletal Muscle	Protein Coding	1
1092	ACTA2	Actin Alpha 2, Smooth Muscle	Protein Coding	1
1093	ACTB	Actin Beta	Protein Coding	1
1094	ACTG1	Actin Gamma 1	Protein Coding	1
1095	ACTG2	Actin Gamma 2, Smooth Muscle	Protein Coding	1
1096	ACTN1	Actinin Alpha 1	Protein Coding	1
1097	ACTN2	Actinin Alpha 2	Protein Coding	1
1098	ACTN3	Actinin Alpha 3	Protein Coding	1
1099	ACTN4	Actinin Alpha 4	Protein Coding	1
1100	RHOJ	Ras Homolog Family Member J	Protein Coding	1
1101	RHOQ	Ras Homolog Family Member Q	Protein Coding	1
1102	CDH20	Cadherin 20	Protein Coding	1
1103	CDH22	Cadherin 22	Protein Coding	1
1104	CDH23	Cadherin Related 23	Protein Coding	1
1105	CDH24	Cadherin 24	Protein Coding	1
1106	CDH26	Cadherin 26	Protein Coding	1
1107	DOCK1	Dedicator Of Cytokinesis 1	Protein Coding	1
1108	DSP	Desmoplakin	Protein Coding	1
1109	FBLIM1	Filamin Binding LIM Protein 1	Protein Coding	1
1110	FLNA	Filamin A	Protein Coding	1
1111	FLNB	Filamin B	Protein Coding	1
1112	FLNC	Filamin C	Protein Coding	1
1113	FOSB	FosB Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
1114	FOSL1	FOS Like 1, AP-1 Transcription Factor Subunit	Protein Coding	1
1115	FOSL2	FOS Like 2, AP-1 Transcription Factor Subunit	Protein Coding	1
1116	MYL11	Myosin Light Chain 11	Protein Coding	1
1117	ILK	Integrin Linked Kinase	Protein Coding	1
1118	IRS2	Insulin Receptor Substrate 2	Protein Coding	1
1119	IRS4	Insulin Receptor Substrate 4	Protein Coding	1
1120	JUNB	JunB Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
1121	JUND	JunD Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
1122	MYH15	Myosin Heavy Chain 15	Protein Coding	1
1123	KRT18	Keratin 18	Protein Coding	1
1124	LIMS1	LIM Zinc Finger Domain Containing 1	Protein Coding	1
1125	LIMS2	LIM Zinc Finger Domain Containing 2	Protein Coding	1
1126	CLEC18C	C-Type Lectin Domain Family 18 Member C	Protein Coding	1
1127	MUC1	Mucin 1, Cell Surface Associated	Protein Coding	1
1128	MYH1	Myosin Heavy Chain 1	Protein Coding	1
1129	MYH10	Myosin Heavy Chain 10	Protein Coding	1
1130	MYH11	Myosin Heavy Chain 11	Protein Coding	1
1131	MYH13	Myosin Heavy Chain 13	Protein Coding	1
1132	MYH14	Myosin Heavy Chain 14	Protein Coding	1
1133	MYH2	Myosin Heavy Chain 2	Protein Coding	1
1134	MYH3	Myosin Heavy Chain 3	Protein Coding	1
1135	MYH4	Myosin Heavy Chain 4	Protein Coding	1
1136	MYH6	Myosin Heavy Chain 6	Protein Coding	1
1137	MYH7	Myosin Heavy Chain 7	Protein Coding	1
1138	MYH7B	Myosin Heavy Chain 7B	Protein Coding	1
1139	MYH8	Myosin Heavy Chain 8	Protein Coding	1
1140	MYH9	Myosin Heavy Chain 9	Protein Coding	1
1141	MYL1	Myosin Light Chain 1	Protein Coding	1
1142	MYL2	Myosin Light Chain 2	Protein Coding	1
1143	MYL3	Myosin Light Chain 3	Protein Coding	1
1144	MYL4	Myosin Light Chain 4	Protein Coding	1
1145	MYL5	Myosin Light Chain 5	Protein Coding	1
1146	MYL6	Myosin Light Chain 6	Protein Coding	1
1147	MYL7	Myosin Light Chain 7	Protein Coding	1
1148	MYO10	Myosin X	Protein Coding	1
1149	MYO15A	Myosin XVA	Protein Coding	1
1150	MYO18B	Myosin XVIIIB	Protein Coding	1
1151	MYO1A	Myosin IA	Protein Coding	1
1152	MYO1B	Myosin IB	Protein Coding	1
1153	MYO1C	Myosin IC	Protein Coding	1
1154	MYO1D	Myosin ID	Protein Coding	1
1155	MYO1E	Myosin IE	Protein Coding	1
1156	MYO1F	Myosin IF	Protein Coding	1
1157	MYO1G	Myosin IG	Protein Coding	1
1158	MYO3A	Myosin IIIA	Protein Coding	1
1159	MYO3B	Myosin IIIB	Protein Coding	1
1160	MYO5A	Myosin VA	Protein Coding	1
1161	MYO6	Myosin VI	Protein Coding	1
1162	MYO7A	Myosin VIIA	Protein Coding	1
1163	MYO9A	Myosin IXA	Protein Coding	1
1164	MYO9B	Myosin IXB	Protein Coding	1
1165	NACA	Nascent Polypeptide Associated Complex Subunit Alpha	Protein Coding	1
1166	NCK2	NCK Adaptor Protein 2	Protein Coding	1
1167	NOS2	Nitric Oxide Synthase 2	Protein Coding	1
1168	PARVA	Parvin Alpha	Protein Coding	1
1169	PARVB	Parvin Beta	Protein Coding	1
1170	DCHS1	Dachsous Cadherin-Related 1	Protein Coding	1
1171	FERMT2	FERM Domain Containing Kindlin 2	Protein Coding	1
1172	PPP2R5D	Protein Phosphatase 2 Regulatory Subunit B''Delta	Protein Coding	1
1173	PTGS2	Prostaglandin-Endoperoxide Synthase 2	Protein Coding	1
1174	RSU1	Ras Suppressor Protein 1	Protein Coding	1
1175	SNAI1	Snail Family Transcriptional Repressor 1	Protein Coding	1
1176	SNAI2	Snail Family Transcriptional Repressor 2	Protein Coding	1
1177	TESK1	Testis Associated Actin Remodelling Kinase 1	Protein Coding	1
1178	TGFB1I1	Transforming Growth Factor Beta 1 Induced Transcript 1	Protein Coding	1
1179	TMSB4X	Thymosin Beta 4 X-Linked	Protein Coding	1
1180	TMSB4Y	Thymosin Beta 4 Y-Linked	Protein Coding	1
1181	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1

Disorders associated with ERK Signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Bladder cancer	Enrichment	ATM, BRCA1, CDKN1A, CDKN2A, CTNNA3, CTNNB1, EGFR, ERBB2, ERBB3, FGFR3, HRAS, KRAS, NF1, PTEN, RB1, TP53, TSC1	10.88
2	Noonan syndrome 1	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, RAF1, RRAS, RRAS2, SOS1, SOS2	10.77
3	Gastric cancer	Enrichment	APC, ATM, BRCA1, CASP10, CDH1, CDK4, CDKN2A, CHEK2, ERBB2, FGFR2, IL1B, KRAS, NBN, NF1, PTEN, SMAD4, STK11, TP53	10.51
4	Human immunodeficiency virus type 1	Enrichment	CCL11, CCL2, CCL3, CCL3L1, CCL5, CCR2, CCR5, CX3CR1, CXCL12, CXCR1, IL10, IL19	10.37
5	Colorectal cancer	Enrichment	AKT1, APC, ATM, AURKA, BAX, BRAF, BRCA1, CCND1, CDH1, CHEK2, CTNNA1, CTNNB1, EP300, ERBB2, FGFR2, FGFR3, FZD3, IGF2, MET, NRAS, PIK3R1, SMAD4, SOX9, SRC, TP53	10.32
6	Ovarian cancer	Enrichment	AKT1, ALK, APC, ATM, BMPR1A, BRCA1, CDH1, CDKN1B, CDKN2A, CHEK2, CTNNB1, EGFR, ERBB2, FANCD2, KIT, KRAS, MET, NBN, NTRK1, PDGFRA, PTCH1, PTEN, RB1, RRAS2, TP53, TSC2	9.83
7	Rasopathy	Enrichment	BRAF, CBL, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NF1, NRAS, RAF1, RRAS2, SOS1, SOS2	9.22
8	Inherited cancer-predisposing syndrome	Enrichment	ALK, APC, ATM, BMPR1A, BRCA1, CDH1, CDK4, CDKN1B, CDKN2A, CHEK2, CTNNA1, EGFR, KIT, MAX, MET, NBN, NF1, PDGFRA, PRKAR1A, PTCH1, PTEN, RB1, SMAD4, STK11, SUFU, TP53, TSC1, TSC2, VHL	9.10
9	Lip and oral cavity carcinoma	Enrichment	ABL1, BRAF, CDKN2A, EGFR, HRAS, KIT, RB1, STK11, TP53	8.74
10	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	COL1A1, COL3A1, COL5A1, COL5A2, EFEMP2, ELN, FBN1, FBN2, NOTCH1, SMAD2, SMAD3, SMAD4, TGFB2, TGFB3, TGFBR1, TGFBR2	8.68
11	Connective tissue disease	Enrichment	ACTA2, COL11A1, COL12A1, COL2A1, COL5A1, COL9A1, COL9A3, EFEMP1, FBN1, FGFR3, FLNB	8.18
12	Stickler syndrome	Enrichment	BMP4, COL11A1, COL2A1, COL9A1, COL9A2, COL9A3, VCAN	8.13
13	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NRAS, RAF1, SOS1	7.75
14	Lung non-small cell carcinoma	Enrichment	BRAF, EGFR, ERBB2, HRAS, KRAS, MAP2K1, NRAS	7.57
15	Loeys-dietz syndrome	Enrichment	FBN1, SMAD2, SMAD3, TGFB2, TGFB3, TGFBR1, TGFBR2	7.05
16	Adult hepatocellular carcinoma	Enrichment	AXIN1, CASP8, CTNNB1, EGF, TP53, TSC1, TSC2	7.05
17	Junctional epidermolysis bullosa	Enrichment	COL17A1, ITGA6, ITGB4, LAMA3, LAMB3, LAMC2	6.71
18	Lung cancer susceptibility 3	Enrichment	BRAF, EGFR, ERBB2, FGF10, KRAS, ROS1, TP53	6.59
19	Marfan syndrome	Enrichment	COL2A1, FBN1, FBN2, LTBP2, TGFB2, TGFBR1, TGFBR2	6.55
20	Breast cancer	Enrichment	AKT1, APC, ATM, BRCA1, CASP8, CDH1, CDKN2B, CHEK2, GNG3, IL2, IL7R, JUN, KRAS, NBN, PTCH2, PTEN, RAD51, TP53	6.50
21	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	COL17A1, ITGB4, LAMA3, LAMB3, LAMC2	6.49
22	Junctional epidermolysis bullosa non-herlitz type	Enrichment	COL17A1, ITGB4, LAMA3, LAMB3, LAMC2	6.49
23	Classic ehlers-danlos syndrome	Enrichment	COL1A1, COL1A2, COL5A1, COL5A2, TGFBR1	6.39
24	Ehlers-danlos syndrome	Enrichment	COL1A1, COL1A2, COL3A1, COL5A1, COL5A2, FBN2, SMAD3, TGFB2, TGFBR2	6.29
25	Myeloma, multiple	Enrichment	ATM, AURKA, BRAF, CCND1, CDKN2C, CREBBP, FGFR3, FLT3, IL7R, KRAS, MST1R, NF1, PIK3R2, TCF3, TP53	6.18
26	Melanocytic nevus syndrome, congenital	Enrichment	ALK, BRAF, HRAS, NRAS, RAF1, SOX5	5.94
27	Rhabdomyosarcoma	Enrichment	ALK, BRCA1, CBL, HRAS, NF1, PTCH1, PTEN, TP53	5.87
28	Lung cancer	Enrichment	ALK, BRAF, BRCA1, CASP8, CHEK2, EGFR, ERBB2, FAS, FASLG, KRAS, MET	5.86
29	Nevus, epidermal	Enrichment	COL7A1, FGFR3, HRAS, KRAS, NRAS	5.86
30	Pilomyxoid astrocytoma	Enrichment	BRAF, FGFR1, KRAS, NTRK2, RAF1	5.86
31	Bethlem muscular dystrophy	Enrichment	COL12A1, COL6A1, COL6A2, COL6A3	5.81
32	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ACTG1, COL11A1, COL11A2, KITLG, MYH14, MYH9, MYO1A, MYO1C, MYO6, MYO7A, TNC	5.79
33	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	5.72
34	Cardiofaciocutaneous syndrome	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	5.72
35	Lung squamous cell carcinoma	Enrichment	ALK, CDKN2A, EGFR, FGFR3, KRAS	5.36
36	Diffuse large b-cell lymphoma	Enrichment	BRAF, BTK, CHEK2, CREBBP, FOXO1, NBN, PTEN, TP53	5.17
37	Ullrich congenital muscular dystrophy 1a	Enrichment	COL12A1, COL6A1, COL6A2, COL6A3	5.12
38	Melanoma	Enrichment	BRAF, CDKN2A, CHEK2, FBN1, PTEN, STK11	5.11
39	Pancreatic cancer	Enrichment	ATM, BRCA1, CDKN2A, CHEK2, KRAS, NBN, SMAD4, STK11, TP53	5.08
40	Focal cortical dysplasia, type ii	Enrichment	MTOR, RHEB, TSC1, TSC2	4.89
41	Isolated focal cortical dysplasia type ii	Enrichment	MTOR, RHEB, TSC1, TSC2	4.89
42	Type 2 diabetes mellitus	Enrichment	AKT2, HNF1A, HNF1B, HNF4A, IL6, INSR, IRS1, IRS2, TCF7L2	4.89
43	Gallbladder cancer	Enrichment	BRAF, CTNNB1, KRAS, SMAD4, TP53	4.84
44	Ehlers-danlos syndrome, classic type, 1	Enrichment	COL1A1, COL1A2, COL5A1, COL5A2	4.66
45	Giant cell glioblastoma	Enrichment	ATM, EGFR, FGFR1, FGFR3, NFKBIA, ROS1, TP53	4.51
46	Renal hypodysplasia/aplasia 3	Enrichment	BMP4, FGFR3, FRAS1, FREM1, FREM2	4.45
47	Hereditary breast carcinoma	Enrichment	AKT1, APC, ATM, BRCA1, CDH1, CHEK2, KRAS, NBN, PTEN, RAD51, TP53	4.38
48	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGF10, FGFR2, FGFR3	4.35
49	Multiple epiphyseal dysplasia due to collagen 9 anomaly	Enrichment	COL9A1, COL9A2, COL9A3	4.35
50	Collagen vi-related dystrophies	Enrichment	COL6A1, COL6A2, COL6A3	4.35
51	High bone mass osteogenesis imperfecta	Enrichment	BMP1, COL1A1, COL1A2	4.35
52	Intermediate collagen vi-related muscular dystrophy	Enrichment	COL6A1, COL6A2, COL6A3	4.35
53	Digenic alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	4.35
54	Mccune-albright syndrome	Enrichment	COL2A1, FBN1, GNAS	4.29
55	Langerhans cell histiocytosis	Enrichment	BRAF, MAP2K1, NRAS	4.29
56	Nk-cell enteropathy	Enrichment	AURKB, AXL, CHEK2, ERBB4, IGF1R, JAK3	4.26
57	Noonan syndrome 3	Enrichment	HRAS, KRAS, RAF1, SOS1	4.22
58	Robinow syndrome, autosomal recessive 1	Enrichment	DVL1, FZD2, ROR2, WNT5A	4.21
59	Hemimegalencephaly	Enrichment	AKT3, MTOR, PTEN, RHEB	4.21
60	Differentiated thyroid carcinoma	Enrichment	ALK, BRAF, HRAS, KRAS, NRAS, NTRK1, NTRK3	4.14
61	Arteriovenous malformation	Enrichment	EPHB4, HRAS, MAP2K1, RASA1, TEK	4.10
62	Hereditary breast ovarian cancer syndrome	Enrichment	ATM, BRCA1, CHEK2, CTNNA1, CTNNA2, KRAS, NBN, NF1, PTCH1, PTEN, RAD51, TP53	4.09
63	T-b+ severe combined immunodeficiency due to cd3delta/cd3epsilon/cd3zeta	Enrichment	CD247, CD3D, CD3E	4.05
64	Nonsyndromic hearing loss	Enrichment	ACTG1, CDH23, COL11A2, MYH14, MYO15A, MYO3A, MYO6, MYO7A	4.02
65	Myopia	Enrichment	COL11A1, COL2A1, COL4A4, FBN1, MYH11	3.91
66	Myopathy, x-linked, with excessive autophagy	Enrichment	EPHB4, HRAS, MAP2K1, RASA1, TEK	3.82
67	Cakut	Enrichment	ACTG1, COL4A1, FRAS1, FREM2, GDF6, HNF1B, LIFR	3.80
68	Nephrotic syndrome	Enrichment	COL4A3, COL4A4, COL4A5, FN1, ITGA3, LAMA5, LAMB2, PLCE1	3.80
69	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	FLT3, KIT, MYH11	3.76
70	Autosomal recessive stickler syndrome	Enrichment	COL9A1, COL9A2, COL9A3	3.76
71	Glioma	Enrichment	FGFR2, NTRK3, PTEN	3.76
72	Li-fraumeni syndrome	Enrichment	CDKN2A, CHEK2, MDM2, TP53	3.76
73	Testicular germ cell tumor	Enrichment	FGFR3, KIT, KITLG, STK11	3.76
74	Autosomal recessive robinow syndrome	Enrichment	DVL1, FZD2, ROR2, WNT5A	3.76
75	Keratoconus	Enrichment	COL1A1, COL4A1, COL5A2, TSC1	3.76
76	Adrenocortical carcinoma	Enrichment	CDKN2A, CTNNB1, PRKAR1A, TP53	3.76
77	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10, IL10RA, IL10RB, TGFB1	3.76
78	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	3.70
79	Pediatric systemic lupus erythematosus	Enrichment	IRAK1, SPP1, STAT4	3.70
80	Hepatocellular carcinoma	Enrichment	APC, AXIN1, CASP8, CTNNB1, MET, NBN, TP53	3.68
81	Skin disease	Enrichment	COL17A1, COL7A1, ITGB4, LAMB3, LAMC2, NCSTN, NF1	3.68
82	Brachydactyly, type a1	Enrichment	BMPR1B, GDF5, IHH	3.67
83	Osteogenic sarcoma	Enrichment	CHEK2, RB1, TP53	3.67
84	Loeys-dietz syndrome 1	Enrichment	SMAD2, TGFBR1, TGFBR2	3.67
85	Hamartoma	Enrichment	FGFR3, TSC1, TSC2	3.67
86	Testicular germ cell cancer	Enrichment	FGFR3, KIT, STK11	3.67
87	Bone osteosarcoma	Enrichment	CHEK2, RB1, TP53	3.67
88	Gliosarcoma	Enrichment	ATM, EGFR, FGFR1, FGFR3, NFKBIA, TP53	3.66
89	Microform holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1, PTCH1, SUFU	3.66
90	Prostate cancer	Enrichment	ATM, BRCA1, CDH1, CHEK2, EPHB2, NBN, PTEN, TP53	3.65
91	Non-syndromic genetic deafness	Enrichment	ACTG1, CDH23, MYH14, MYO15A, MYO3A, MYO6, MYO7A	3.64
92	Glioma susceptibility 1	Enrichment	ERBB2, H3-3A, H3C1, TP53	3.62
93	Heritable pulmonary arterial hypertension	Enrichment	ACVRL1, BMPR2, GDF2, SMAD9, SOX17	3.58
94	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A, CDKN1B, CDKN2B, CDKN2C	3.41
95	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF, HRAS, NRAS, PTEN	3.41
96	Squamous cell carcinoma, head and neck	Enrichment	EGFR, PTEN, TNFRSF10B, TP53	3.41
97	Capillary malformation-arteriovenous malformation 1	Enrichment	EPHB4, KRAS, MAP2K1, RASA1	3.41
98	Renal cell carcinoma, papillary, 1	Enrichment	ATM, MET, MTOR, VHL	3.41
99	Hereditary hemorrhagic telangiectasia	Enrichment	ACVRL1, GDF2, RASA1, SMAD4	3.41
100	Follicular thyroid carcinoma	Enrichment	BRAF, HRAS, NRAS, PTEN	3.41
101	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	ABL1, CDKN2A, FLT3, TP53	3.41
102	Primary hyperaldosteronism	Enrichment	BRAF, CACNA1H, GNAS, TP53	3.38
103	Alport syndrome 3a, autosomal dominant	Enrichment	COL4A3, COL4A4, COL4A5	3.38
104	Hemifacial hyperplasia	Enrichment	FGFR2, FGFR3, FLNC	3.38
105	Fuchs' endothelial dystrophy	Enrichment	COL8A2, TCF4, ZEB1	3.38
106	Autosomal dominant alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	3.38
107	Histiocytoid hemangioma	Enrichment	FOS, FOSB, VIM	3.38
108	Alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	3.38
109	Primary hypereosinophilic syndrome	Enrichment	FGFR1, PDGFRA, PDGFRB	3.38
110	Juvenile myelomonocytic leukemia	Enrichment	CBL, KRAS, NF1, NRAS, RRAS	3.37
111	Meningioma	Enrichment	AKT1, PDGFB, PTEN, SMO, SUFU	3.37
112	Myopathy	Enrichment	ACTA1, COL6A1, COL6A2, COL6A3, FBN1, MYH2, MYH7	3.34
113	Epidermolysis bullosa	Enrichment	COL7A1, ITGA6, LAMB3	3.32
114	Familial cerebral saccular aneurysm	Enrichment	ANGPTL6, COL3A1, TGFBR3	3.32
115	Arteriovenous malformations of the brain	Enrichment	BRAF, EGFR, IL6, KRAS, TIMP3	3.28
116	Cutis laxa	Enrichment	COL5A1, EFEMP1, EFEMP2, LTBP4	3.21
117	Behcet syndrome	Enrichment	CCR1, FAS, IL10, IL12A, IL23R, TNFRSF1A	3.20
118	Epidermolysis bullosa, junctional 1b, severe	Enrichment	LAMA3, LAMB3, LAMC2	3.09
119	Hemangioma, capillary infantile	Enrichment	FLT4, KDR, MYH9	3.09
120	Inguinal hernia	Enrichment	COL5A1, EFEMP1, FBN1	3.09
121	Inherited arrhythmogenic cardiomyopathy	Enrichment	DSP, FLNC, MYH7	3.09
122	Brachydactyly, type a2	Enrichment	BMP2, BMPR1B, GDF5	3.08
123	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CDH1, CTNNA1, KRAS	3.08
124	Robinow syndrome, autosomal dominant 1	Enrichment	DVL1, FZD2, WNT5A	3.08
125	Autoimmune lymphoproliferative syndrome	Enrichment	CASP10, FAS, FASLG	3.08
126	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3, CCND2, PIK3R2	3.08
127	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	ABL1, KRAS, NRAS	3.08
128	Aortic aneurysm	Enrichment	FBN1, SMAD3, TGFBR1	3.08
129	Craniopharyngioma	Enrichment	APC, BRAF, CTNNB1	3.08
130	Autosomal dominant robinow syndrome	Enrichment	DVL1, FZD2, WNT5A	3.08
131	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGA2, ITGA2B, ITGB3	3.03
132	Osteoporosis	Enrichment	COL1A1, COL1A2, LRP5, SRC, WNT1	3.01
133	Medulloblastoma	Enrichment	APC, CTNNB1, PTCH1, PTCH2, SUFU	3.01
134	Endometrial cancer	Enrichment	ATM, BRCA1, CDH1, CHEK2, FGFR2, PTEN	2.94
135	Multiple sclerosis	Enrichment	ITGB4, LAMA5, LAMB1, TNFRSF1A	2.93
136	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	CDH23, COL11A2, HGF, MET, MYH9, MYO15A, MYO3A, MYO6, MYO7A, ROR1	2.93
137	Acromicric dysplasia	Enrichment	FBN1, LTBP3	2.90
138	Lymphatic malformation 1	Enrichment	EPHB4, FLT4	2.90
139	Amelogenesis imperfecta, type ia	Enrichment	COL17A1, LAMB3	2.90
140	Spondyloepimetaphyseal dysplasia, strudwick type	Enrichment	COL2A1, FN1	2.90
141	Spondylometaphyseal dysplasia, corner fracture type	Enrichment	COL2A1, FN1	2.90
142	Visceral neuropathy, familial, 1, autosomal recessive	Enrichment	ERBB3, FLNA	2.90
143	Otospondylomegaepiphyseal dysplasia, autosomal recessive	Enrichment	COL11A2, COL2A1	2.90
144	Intracranial hypertension, idiopathic	Enrichment	EPHB4, FLT4	2.90
145	Dermatofibrosarcoma protuberans	Enrichment	COL1A1, PDGFB	2.90
146	Piebald trait	Enrichment	KIT, SNAI2	2.90
147	Pfeiffer syndrome	Enrichment	FGFR1, FGFR2	2.90
148	Jackson-weiss syndrome	Enrichment	FGFR1, FGFR2	2.90
149	Otospondylomegaepiphyseal dysplasia, autosomal dominant	Enrichment	COL11A2, COL2A1	2.90
150	Ehlers-danlos syndrome, arthrochalasia type, 2	Enrichment	COL1A1, COL1A2	2.90
151	Fibrochondrogenesis	Enrichment	COL11A1, COL11A2	2.90
152	Childhood hepatocellular carcinoma	Enrichment	CTNNB1, MET	2.90
153	Aortic dissection	Enrichment	COL3A1, FBN1	2.90
154	Split hand-foot malformation	Enrichment	FGFR2, LEF1	2.90
155	Stickler syndrome, type ii	Enrichment	COL11A1, COL1A1	2.90
156	Loeys-dietz syndrome 4	Enrichment	TGFB2, TGFB3	2.90
157	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	2.90
158	Hereditary lymphedema i	Enrichment	EPHB4, FLT4	2.90
159	Interfrontal craniofaciosynostosis	Enrichment	FGFR1, FREM1	2.90
160	Ehlers-danlos/osteogenesis imperfecta syndrome	Enrichment	COL1A1, COL1A2	2.90
161	Localized junctional epidermolysis bullosa, non-herlitz type	Enrichment	COL17A1, ITGB4	2.90
162	Hyperinsulinism due to hnf1a deficiency	Enrichment	HNF1A, HNF4A	2.90
163	X-linked diffuse leiomyomatosis-alport syndrome	Enrichment	COL4A5, COL4A6	2.90
164	Ear malformation	Enrichment	CDH23, COL11A2, MYO15A, MYO6, MYO7A	2.87
165	Cervical cancer	Enrichment	FGFR3, TP53	2.86
166	Pulmonic stenosis	Enrichment	BRAF, SOS1	2.86
167	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	GNAS, PRKAR1A	2.86
168	Encephalocraniocutaneous lipomatosis	Enrichment	FGFR1, KRAS	2.86
169	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	2.86
170	Angioma, tufted	Enrichment	GNA14, KDR	2.86
171	Cervix carcinoma	Enrichment	FGFR3, TP53	2.86
172	Kidney disease	Enrichment	COL4A3, COL4A4, COL4A5, LAMB2, TSC1	2.86
173	Bethlem myopathy 1a	Enrichment	COL6A1, COL6A2, COL6A3	2.86
174	Intervertebral disc disease	Enrichment	COL11A1, COL9A2, COL9A3	2.86
175	Sensorineural hearing loss	Enrichment	CDH23, COL11A2, COL9A1, HGF, MYO15A, MYO3A, MYO7A	2.85
176	Renal cell carcinoma, nonpapillary	Enrichment	HNF1A, HNF1B, MET, MTOR	2.81
177	Anterior segment dysgenesis 5	Enrichment	BMP4, COL4A1, PAX6	2.79
178	Lobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1, PTCH1	2.72
179	Exudative vitreoretinopathy 1	Enrichment	CTNNB1, FZD4, LRP5	2.71
180	Von hippel-lindau syndrome	Enrichment	CCND1, FANCD2, VHL	2.71
181	Rhabdomyosarcoma 2	Enrichment	FOXO1, NF1, TP53	2.71
182	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	BMPR1A, SMAD4, STK11	2.71
183	Bryant-li-bhoj neurodevelopmental syndrome 2	Enrichment	H3-3A, H3-3B	2.70
184	Autosomal dominant macrothrombocytopenia	Enrichment	ITGA2B, ITGB3, TUBA8, TUBB1	2.69
185	Dilated cardiomyopathy	Enrichment	ACTA1, ACTN2, DSP, FBN1, FLNC, LAMA2, MYH6, MYH7, MYL2	2.69
186	Spastic paraplegia 4, autosomal dominant	Enrichment	COL3A1, GNAS, TCF4	2.61
187	Orthostatic intolerance	Enrichment	COL5A1, FBN1, RPS6KA3	2.61
188	Melanoma, cutaneous malignant 1	Enrichment	BRAF, CDK4, CDKN2A, CDKN2B, STK11	2.59
189	Leukemia, acute lymphoblastic	Enrichment	CDKN2A, FLT3, GNB1, NBN	2.52
190	Uterine corpus cancer	Enrichment	ATM, BRCA1, CHEK2, PTEN	2.52
191	Familial thoracic aortic aneurysm and dissection	Enrichment	COL3A1, FBN1, MYH11	2.50
192	Heart, malformation of	Enrichment	COL11A2, COL2A1, MAPK1, MYH6	2.49
193	Semilobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	2.49
194	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	FGF17, FGF8, FGFR1, GNRH1	2.49
195	Blepharocheilodontic syndrome 1	Enrichment	CDH1, CTNND1	2.44
196	Loeys-dietz syndrome 2	Enrichment	TGFBR1, TGFBR2	2.44
197	Lymphangioleiomyomatosis	Enrichment	TSC1, TSC2	2.44
198	Fibrodysplasia ossificans progressiva	Enrichment	ACVR1, BMPR2	2.44
199	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1, RARB	2.44
200	Infantile myofibromatosis	Enrichment	NOTCH3, PDGFRB	2.44
201	Congenital fibrosarcoma	Enrichment	SUFU, TP53	2.44
202	Li-fraumeni syndrome 1	Enrichment	CHEK2, TP53	2.44
203	Sarcoma	Enrichment	CHEK2, TP53	2.44
204	Juvenile polyposis of infancy	Enrichment	BMPR1A, PTEN	2.44
205	Pleomorphic rhabdomyosarcoma	Enrichment	NF1, TP53	2.44
206	Ventricular septal defect	Enrichment	BRAF, RPS6KA3, TEK	2.44
207	Crouzon syndrome	Enrichment	FGFR2, FGFR3	2.43
208	Contractural arachnodactyly, congenital	Enrichment	FBN1, FBN2	2.43
209	Achondroplasia	Enrichment	FBN1, FGFR3	2.43
210	Larsen syndrome	Enrichment	FGFR3, FLNB	2.43
211	Klippel-feil syndrome 1, autosomal dominant	Enrichment	GDF6, MYO18B	2.43
212	Hematuria, benign familial, 1	Enrichment	COL4A3, COL4A4	2.43
213	Telecanthus	Enrichment	COL11A1, COL5A2	2.43
214	Spondylocarpotarsal synostosis syndrome	Enrichment	FLNB, MYH3	2.43
215	Ehlers-danlos syndrome, classic type, 2	Enrichment	COL5A1, COL5A2	2.43
216	Weill-marchesani syndrome 1	Enrichment	FBN1, LTBP2	2.43
217	Autosomal recessive cutis laxa type i	Enrichment	EFEMP2, LTBP1	2.43
218	Chromophobe renal cell carcinoma	Enrichment	HNF1A, HNF1B	2.43
219	Melanoma of soft tissue	Enrichment	ATF1, CREB1	2.43
220	Geleophysic dysplasia	Enrichment	FBN1, LTBP3	2.43
221	Basal cell nevus syndrome 1	Enrichment	PTCH1, PTCH2, SUFU	2.43
222	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	ACVRL1, PSEN1, RASA1	2.43
223	Basal cell carcinoma 1	Enrichment	PTCH1, PTCH2, RASA1	2.43
224	Congenital fibrosis of the extraocular muscles	Enrichment	COL25A1, TUBB2B, TUBB3	2.43
225	Breast adenocarcinoma	Enrichment	AKT1, KRAS, TP53	2.43
226	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3, STAT3	2.39
227	Bleeding disorder, platelet-type, 16	Enrichment	ITGA2B, ITGB3	2.39
228	Psoriatic arthritis	Enrichment	LTA, TNF	2.39
229	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	GNA11, PIK3R1	2.39
230	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	2.39
231	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL2, MYC	2.39
232	Spermatocytoma	Enrichment	FGFR3, HRAS	2.39
233	Anastomosing haemangioma	Enrichment	GNA11, GNA14	2.39
234	Amelogenesis imperfecta, type ie	Enrichment	COL17A1, ITGB6, LAMB3	2.36
235	Nemaline myopathy	Enrichment	ACTA1, FLNC, MYO18B	2.36
236	Primary bone dysplasia	Enrichment	COL1A1, COL1A2, FGFR3	2.36
237	Craniosynostosis	Enrichment	FGFR2, FGFR3, TCF12, TCF20	2.32
238	Familial hypertrophic cardiomyopathy	Enrichment	ACTN2, FLNC, MYH7, MYL2, MYL3	2.24
239	Thyroid carcinoma, familial medullary	Enrichment	ESR2, NTRK1	2.24
240	Nasopharyngeal carcinoma	Enrichment	NFKBIA, TP53	2.24
241	Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures	Enrichment	CACNA1A, CACNA1C	2.24
242	Migraine without aura	Enrichment	ESR1, TNF	2.24
243	Osteochondrodysplasia	Enrichment	COL1A1, COL1A2, FGFR3	2.23
244	Presynaptic congenital myasthenic syndromes	Enrichment	COL13A1, LAMA5, MYO9A	2.23
245	Pulmonary hypertension, primary, 1	Enrichment	ACVRL1, BMPR2, GDF2, SOX17	2.23
246	Breast-ovarian cancer, familial 1	Enrichment	ATM, BRCA1, CHEK2, NBN	2.23
247	Leukemia, chronic myeloid	Enrichment	ABL1, KRAS, NRAS	2.20
248	Multiple enchondromatosis, maffucci type	Enrichment	COL2A1, HIF1A, VHL	2.20
249	Essential thrombocythemia	Enrichment	JAK2, THPO, TP53	2.20
250	Common variable immunodeficiency	Enrichment	CD40LG, NFKB1, TNFRSF13B	2.20
251	Overgrowth syndrome	Enrichment	MTOR, PIK3R1, PTCH1	2.20
252	Hirschsprung disease 1	Enrichment	ERBB2, ERBB3, IHH, NRG3, SMO, SOX10	2.18
253	Pectus excavatum	Enrichment	FBN1, TCF20, TGFBR1	2.17
254	Rare genetic deafness	Enrichment	ACTG1, CDH23, COL11A2, COL4A5, MYH9, MYO15A, MYO6, MYO7A	2.17
255	Hepatoblastoma	Enrichment	APC, COL7A1, CTNNB1, FGFR3, TP53	2.16
256	Ehlers-danlos syndrome, arthrochalasia type, 1	Enrichment	COL1A1, COL1A2	2.14
257	Brain small vessel disease 1 with or without ocular anomalies	Enrichment	COL4A1, COL4A2	2.14
258	Alport syndrome 2, autosomal recessive	Enrichment	COL4A3, COL4A4	2.14
259	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	ACTG2, MYH11	2.14
260	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3, PIK3R2	2.14
261	Glaucoma 3, primary infantile, b	Enrichment	LTBP2, TEK	2.14
262	Maturity-onset diabetes of the young, type 3	Enrichment	HNF1A, HNF4A	2.14
263	Saethre-chotzen syndrome	Enrichment	FGFR2, FGFR3	2.14
264	Macular dystrophy, vitelliform, 3	Enrichment	IMPG1, IMPG2	2.14
265	Multiple synostoses syndrome	Enrichment	GDF5, GDF6	2.14
266	Weill-marchesani syndrome	Enrichment	FBN1, LTBP2	2.14
267	Corneal dystrophy	Enrichment	COL17A1, ZEB1	2.14
268	Autosomal recessive alport syndrome	Enrichment	COL4A3, COL4A4	2.14
269	Osteogenesis imperfecta with normal sclerae, dominant form	Enrichment	COL1A1, COL1A2	2.14
270	Mitral valve insufficiency	Enrichment	FBN1, MYH11	2.14
271	Non-syndromic bicoronal craniosynostosis	Enrichment	FGFR3, TCF12	2.14
272	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB, FOSB	2.14
273	Thrombocytopenia	Enrichment	ACVRL1, CYCS, ITGA2B, ITGB3, SMAD4, SRC, THPO, TUBB1	2.14
274	Systemic lupus erythematosus	Enrichment	ETS1, IL10, ITGAM, SPP1, TNF, TNFSF4	2.14
275	Cerebral palsy	Enrichment	CACNA1A, CACNA1C, COL4A1, COL4A2, GNB1, PDGFRB	2.14
276	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF, TP53	2.10
277	Auriculocondylar syndrome 1	Enrichment	GNAI3, PLCB4	2.10
278	Achromatopsia 4	Enrichment	GNAI3, GNAT2	2.10
279	Lung sarcomatoid carcinoma	Enrichment	KRAS, TP53	2.10
280	Noonan syndrome with multiple lentigines	Enrichment	BRAF, RAF1	2.10
281	Knobloch syndrome	Enrichment	COL18A1, PAK2	2.10
282	Aortic aneurysm, familial thoracic 1	Enrichment	COL3A1, FBN1, NOTCH1, SMAD3	2.10
283	Kallmann syndrome	Enrichment	FGF17, FGF8, FGFR1, SEMA3A	2.09
284	Asthma	Enrichment	CCL11, IL13, TNF	2.08
285	Peters-plus syndrome	Enrichment	BMP4, COL4A1, PAX6	2.07
286	Leukemia, acute myeloid	Enrichment	FANCD2, FLT3, JAK2, KIT, KRAS, NRAS, TP53	2.05
287	Non-immune hydrops fetalis	Enrichment	ANGPT2, EPHB4, FLT4, FZD6, HRAS, KRAS	2.03
288	Cardiomyopathy, familial hypertrophic, 1	Enrichment	FLNC, MYH6, MYH7, MYH7B	2.03
289	Lymphoma, non-hodgkin, familial	Enrichment	BRAF, CASP10, TP53	2.02
290	Exudative vitreoretinopathy	Enrichment	CTNNB1, FZD4, LRP5	2.02
291	Diaphragmatic hernia, congenital	Enrichment	FBN1, FRAS1, FREM2	2.01
292	Amelogenesis imperfecta	Enrichment	COL17A1, LAMB3, LTBP3	2.01
293	Osteogenesis imperfecta, type iii	Enrichment	BMP1, COL1A1, COL1A2, WNT1	1.99
294	Rare genetic intellectual disability	Enrichment	CREBBP, EP300, GNAO1, MTOR	1.99
295	Septopreoptic holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1, PTCH1	1.99
296	Midline interhemispheric variant of holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1, PTCH1	1.99
297	Desmoid disease, hereditary	Enrichment	APC, CTNNB1	1.98
298	Brachydactyly, type c	Enrichment	BMPR1B, GDF5	1.98
299	Ataxia-telangiectasia	Enrichment	ATM, BRAF	1.98
300	Juvenile polyposis syndrome	Enrichment	BMPR1A, SMAD4	1.98
301	Acromesomelic dysplasia 2a	Enrichment	BMPR1B, GDF5	1.98
302	Acromesomelic dysplasia 2c	Enrichment	BMPR1B, GDF5	1.98
303	Acromesomelic dysplasia 2b	Enrichment	BMPR1B, GDF5	1.98
304	Polycythemia vera	Enrichment	ATM, JAK2	1.98
305	Mycosis fungoides	Enrichment	CD28, TNFRSF1B	1.98
306	Tuberous sclerosis 1	Enrichment	TSC1, TSC2	1.98
307	Alzheimer disease 4	Enrichment	PSEN1, PSEN2	1.98
308	Primary polycythemia	Enrichment	EPOR, VHL	1.98
309	Tethered spinal cord syndrome	Enrichment	BRAF, CREBBP	1.98
310	Breast implant-associated anaplastic large cell lymphoma	Enrichment	JAK1, JAK2	1.98
311	Desmoid tumor	Enrichment	APC, CTNNB1	1.98
312	Dedifferentiated liposarcoma	Enrichment	CDK4, MDM2	1.98
313	Squamous cell carcinoma	Enrichment	RB1, TP53	1.98
314	T-cell acute lymphoblastic leukemia	Enrichment	ABL1, BAX	1.98
315	Adenocarcinoma	Enrichment	ATM, TP53	1.98
316	Laryngeal squamous cell carcinoma	Enrichment	PTEN, TNFRSF10B	1.98
317	Neonatal inflammatory skin and bowel disease	Enrichment	ADAM17, EGFR	1.98
318	Tubulinopathy-associated dysgyria	Enrichment	TUBB2B, TUBB3	1.98
319	Well-differentiated liposarcoma	Enrichment	CDK4, MDM2	1.98
320	Testicular cancer	Enrichment	FGFR3, STK11	1.98
321	Pulmonary arterial hypertension associated with congenital heart disease	Enrichment	BMPR2, SMAD9	1.98
322	Keratoacanthoma	Enrichment	NOTCH1, NOTCH2	1.98
323	Apc-associated polyposis conditions	Enrichment	APC, STK11	1.98
324	Saczary syndrome	Enrichment	CD28, TNFRSF1B	1.98
325	Brittle bone disorder	Enrichment	BMP1, COL1A1, COL1A2, LRP5, WNT1	1.98
326	Acute promyelocytic leukemia	Enrichment	PRKAR1A, STAT3, STAT5B	1.96
327	Migraine with or without aura 1	Enrichment	CACNA1A, CAPN3, ESR1	1.95
328	Macular dystrophy, vitelliform, 2	Enrichment	IMPG1, IMPG2	1.93
329	Visceral myopathy 1	Enrichment	ACTG2, MYH11	1.93
330	Retinal detachment	Enrichment	COL2A1, COL9A3	1.93
331	Congenital myopathy 3 with rigid spine	Enrichment	ACTA1, MYH7	1.93
332	Insulin-like growth factor i	Enrichment	IGF1, IGF1R	1.93
333	Ventricular septal defect 1	Enrichment	BMP2, BMP7	1.93
334	Congenital ptosis	Enrichment	COL25A1, MYH10	1.93
335	Acute myeloid leukemia with maturation	Enrichment	FLT3, KIT	1.93
336	Holoprosencephaly	Enrichment	FGF8, FGFR1	1.93
337	Juvenile glaucoma	Enrichment	EFEMP1, LTBP2	1.93
338	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	FLT3, KIT	1.93
339	Familial porencephaly	Enrichment	COL4A1, COL4A2	1.93
340	Cataract	Enrichment	COL18A1, COL5A1, EPHA2	1.92
341	Cleft lip/palate	Enrichment	BMP4, CDH1, PDGFRA	1.92
342	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	CDH2, DSP, TGFB3	1.92
343	Tetralogy of fallot	Enrichment	EPHB4, FLNC, FLT4, KDR	1.90
344	Knobloch syndrome 1	Enrichment	COL18A1, PAK2	1.89
345	Isolated macular dystrophy	Enrichment	COL4A5, IMPG1, ITGA4	1.86
346	Ellis-van creveld syndrome	Enrichment	GLI1, PRKACA, PRKACB	1.86
347	Colonic benign neoplasm	Enrichment	APC, ATM, CHEK2	1.86
348	Scoliosis	Enrichment	COL2A1, EFEMP1, FBN1, GFAP	1.84
349	Congenital myopathy 4a, autosomal dominant	Enrichment	ACTA1, MYH7, MYL2	1.83
350	Severe combined immunodeficiency	Enrichment	CD247, CD3D, CD3E, CD3G, ZAP70	1.83
351	Myocardial infarction	Enrichment	ESR1, ITGB3, LTA, TNFSF4	1.82
352	Distal arthrogryposis	Enrichment	ACTA1, COL25A1, MYH3, MYL11, ROR2	1.80
353	Polycystic liver disease	Enrichment	CDC25A, CTNNB1, LRP5, LRP6	1.79
354	Autosomal dominant polycystic liver disease	Enrichment	CDC25A, CTNNB1, LRP5, LRP6	1.79
355	Alobar holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1, PTCH1	1.79
356	Atrial septal defect 1	Enrichment	BMP2, TGFB2	1.77
357	Osteogenesis imperfecta, type i	Enrichment	COL1A1, COL1A2	1.77
358	Corneal dystrophy, posterior polymorphous, 1	Enrichment	COL8A2, ZEB1	1.77
359	Cowden syndrome 1	Enrichment	EGFR, PTEN	1.77
360	Fraser syndrome 1	Enrichment	FRAS1, FREM2	1.77
361	Split-hand/foot malformation 1	Enrichment	FGFR2, LEF1	1.77
362	Hemihyperplasia, isolated	Enrichment	IGF2, RHOA	1.77
363	Holoprosencephaly 1	Enrichment	FGF8, FGFR1	1.77
364	Type 1 diabetes mellitus	Enrichment	HNF1A, IL6	1.77
365	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGB4, MYO6	1.77
366	Hemorrhage, intracerebral	Enrichment	COL4A1, COL4A2	1.77
367	Intestinal pseudo-obstruction	Enrichment	ACTG2, MYH11	1.77
368	46,xy disorder of sex development	Enrichment	FGFR3, INSR	1.77
369	Typical nemaline myopathy	Enrichment	ACTA1, CFL2	1.77
370	Hypertrophic cardiomyopathy	Enrichment	ACTN2, MYH7, MYH7B, MYL2, MYL3	1.76
371	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	ACTN2, DSP, FLNC	1.75
372	Hypertension	Enrichment	COL4A4, COL4A5, MYH9	1.75
373	Congenital stationary night blindness	Enrichment	CACNA1F, CACNA2D4, GNAT1, GNB3	1.75
374	Aniridia	Enrichment	EPHA2, PAX6	1.74
375	Melanoma, uveal	Enrichment	GNA11, PLCB4	1.73
376	Inflammatory bowel disease 25, autosomal recessive	Enrichment	RIPK1, TGFB1	1.73
377	Leukemia, chronic lymphocytic	Enrichment	ATM, CCND1, TP53	1.73
378	Stroke, ischemic	Enrichment	FBN1, NOTCH3, PRKCH	1.73
379	Erythrocytosis, familial, 1	Enrichment	EPOR, JAK2	1.70
380	Small cell cancer of the lung	Enrichment	RB1, TP53	1.70
381	Erythrocytosis, familial, 2	Enrichment	FANCD2, VHL	1.70
382	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA1, CTNNA1	1.70
383	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2, NF1	1.70
384	Cholangiocarcinoma	Enrichment	BRCA1, ROS1	1.70
385	Mantle cell lymphoma	Enrichment	ATM, CCND1	1.70
386	Tubulinopathy	Enrichment	TUBB2A, TUBB2B	1.70
387	Retinopathy of prematurity	Enrichment	FZD4, LRP5	1.70
388	Tuberous sclerosis	Enrichment	TSC1, TSC2	1.70
389	Embryonal rhabdomyosarcoma	Enrichment	NF1, TP53	1.70
390	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CBL, CDC42	1.70
391	Pilocytic astrocytoma	Enrichment	KRAS, NF1	1.70
392	Oculomotor apraxia	Enrichment	ATM, SUFU	1.70
393	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	CHEK1, SOS2	1.70
394	Cone-rod dystrophy 6	Enrichment	CACNA1F, CACNA2D4, GNAT2	1.65
395	Meniere disease	Enrichment	CDH23, MYO7A	1.63
396	Osteogenesis imperfecta, type ii	Enrichment	COL1A1, COL1A2	1.63
397	Glaucoma 3, primary congenital, a	Enrichment	LTBP2, TEK	1.63
398	Gastrointestinal stromal tumor	Enrichment	KIT, PDGFRA	1.63
399	Waardenburg syndrome, type 2e	Enrichment	KITLG, SNAI2	1.63
400	Neuropathy, hereditary sensory and autonomic, type v	Enrichment	NGF, NTRK1	1.63
401	Familial isolated restrictive cardiomyopathy	Enrichment	FLNC, MYL2	1.63
402	Beckwith-wiedemann syndrome	Enrichment	COL6A1, COL7A1, IGF2	1.61
403	Patent foramen ovale	Enrichment	FLNA, FLNC, MYH6	1.61
404	Meningioma, familial	Enrichment	PDGFB, PTEN, SUFU	1.61
405	Familial colorectal cancer type x	Enrichment	ATM, BMPR1A, CHEK2	1.61
406	Glanzmann thrombasthenia 1	Enrichment	ITGA2B, ITGB3	1.59
407	Oligoarticular juvenile idiopathic arthritis	Enrichment	IL2RA, STAT4	1.59
408	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	IL2RA, STAT4	1.59
409	Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndrome	Enrichment	BDNF, PAX6	1.58
410	Brugada syndrome	Enrichment	CACNA1C, CACNA2D1, CACNB2, SEMA3A	1.57
411	Hypertelorism	Enrichment	COL11A1, COL1A1, ELN, FGFR2, PAX6, RPS6KA3	1.56
412	Arthrogryposis, distal, type 1a	Enrichment	MET, MYH3	1.52
413	Basal ganglia calcification, idiopathic, 1	Enrichment	PDGFB, PDGFRB	1.52
414	Hemochromatosis, type 1	Enrichment	BMP2, BMP6	1.52
415	Myocarditis	Enrichment	DSP, MYH7	1.52
416	Genetic steroid-resistant nephrotic syndrome	Enrichment	ACTN4, COL4A3, LAMA5, MYO1E	1.51
417	Septooptic dysplasia	Enrichment	FGFR1, SOX2, SOX3	1.50
418	Capillary malformations, congenital	Enrichment	GNA11, RASA1	1.50
419	Fanconi anemia, complementation group d2	Enrichment	FANCD2, VHL	1.50
420	Familial adenomatous polyposis 1	Enrichment	APC, STK11	1.50
421	Robinow syndrome, autosomal dominant 2	Enrichment	DVL1, FZD2	1.50
422	Myeloproliferative neoplasm	Enrichment	CBL, JAK2	1.50
423	Nonsyndromic 46,xx testicular disorders/differences of sex development	Enrichment	SOX3, SOX9	1.50
424	Vascular dementia	Enrichment	NOTCH3, TNF	1.50
425	Acute megakaryocytic leukemia	Enrichment	PTEN, TP53	1.50
426	Diffuse cutaneous systemic sclerosis	Enrichment	CCN2, CCR6	1.50
427	Hereditary pulmonary alveolar proteinosis	Enrichment	CSF2RA, CSF2RB	1.50
428	Maturity-onset diabetes of the young	Enrichment	HNF1A, HNF1B, HNF4A	1.49
429	Microcephaly	Enrichment	ABL1, CAMK2B, COL4A1, COL7A1, CTNNB1, EP300, GNAO1, GNB1, IGF1R, MAPK1, NBN, SYNGAP1, TCF4	1.48
430	Gastroesophageal reflux	Enrichment	COL5A1, RPS6KA3	1.48
431	Renal hypodysplasia/aplasia 1	Enrichment	FRAS1, ITGA8	1.48
432	Lissencephaly	Enrichment	NBN, TUBB2B, TUBB3, TUBG1	1.47
433	Left ventricular noncompaction	Enrichment	ACTN2, DSP, MYH7, MYH7B	1.46
434	Stickler syndrome, type i	Enrichment	COL2A1	1.45
435	Periodic fever, familial, autosomal dominant	Enrichment	TNFRSF1A	1.45
436	Lymphatic malformation 5	Enrichment	EPHB4	1.45
437	Bladder diverticulum	Enrichment	EFEMP1	1.45
438	Cryptophthalmos, unilateral or bilateral, isolated	Enrichment	FREM2	1.45
439	Short stature and advanced bone age with or without early-onset osteoarthritis and/or osteochondritis dissecans	Enrichment	ACAN	1.45
440	Brachydactyly, type b1	Enrichment	ROR2	1.45
441	Erythroleukemia, familial	Enrichment	ERBB3	1.45
442	Hypochondroplasia	Enrichment	FGFR3	1.45
443	Boomerang dysplasia	Enrichment	FLNB	1.45
444	Proteus syndrome	Enrichment	AKT1	1.45
445	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	1.45
446	Paget disease, extramammary	Enrichment	ERBB2	1.45
447	Ectopia lentis 1, isolated, autosomal dominant	Enrichment	FBN1	1.45
448	Epidermolysis bullosa dystrophica, pretibial	Enrichment	COL7A1	1.45
449	Epidermolysis bullosa dystrophica, autosomal dominant	Enrichment	COL7A1	1.45
450	Osteoglophonic dysplasia	Enrichment	FGFR1	1.45
451	Hepatic adenomas, familial	Enrichment	HNF1A	1.45
452	Epiphyseal dysplasia, multiple, with myopia and conductive deafness	Enrichment	COL2A1	1.45
453	Thanatophoric dysplasia, type i	Enrichment	FGFR3	1.45
454	Microspherophakia and/or megalocornea, with ectopia lentis and with or without secondary glaucoma	Enrichment	LTBP2	1.45
455	Ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome	Enrichment	CDH3	1.45
456	Elsahy-waters syndrome	Enrichment	CDH11	1.45
457	Trigonocephaly 1	Enrichment	FGFR1	1.45
458	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	1.45
459	Ehlers-danlos syndrome, cardiac valvular type	Enrichment	COL1A2	1.45
460	Epidermolysis bullosa dystrophica, autosomal recessive	Enrichment	COL7A1	1.45
461	Donohue syndrome	Enrichment	INSR	1.45
462	Contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a	Enrichment	MYH3	1.45
463	Spondylometaphyseal dysplasia, algerian type	Enrichment	COL2A1	1.45
464	Spinocerebellar ataxia 27a	Enrichment	FGF14	1.45
465	Baraitser-winter syndrome 1	Enrichment	ACTB	1.45
466	Hypothyroidism, congenital, nongoitrous, 9	Enrichment	IRS4	1.45
467	Muenke syndrome	Enrichment	FGFR3	1.45
468	Vacterl association with hydrocephalus	Enrichment	PTEN	1.45
469	Premature aging syndrome, penttinen type	Enrichment	PDGFRB	1.45
470	Alport syndrome 1, x-linked	Enrichment	COL4A5	1.45
471	Focal segmental glomerulosclerosis 1	Enrichment	ACTN4	1.45
472	Deafness, autosomal recessive 53	Enrichment	COL11A2	1.45
473	Systemic lupus erythematosus 6	Enrichment	ITGAM	1.45
474	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	1.45
475	Cornelia de lange syndrome 3 with or without midline brain defects	Enrichment	SMC3	1.45
476	Deafness, autosomal recessive 2	Enrichment	MYO7A	1.45
477	Osteoarthritis with mild chondrodysplasia	Enrichment	COL2A1	1.45
478	Otopalatodigital syndrome, type i	Enrichment	FLNA	1.45
479	Intestinal pseudoobstruction, neuronal, chronic idiopathic, x-linked	Enrichment	FLNA	1.45
480	Avascular necrosis of femoral head, primary, 1	Enrichment	COL2A1	1.45
481	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	1.45
482	Hypomagnesemia 4, renal	Enrichment	EGF	1.45
483	Czech dysplasia	Enrichment	COL2A1	1.45
484	Glaucoma 3, primary congenital, d	Enrichment	LTBP2	1.45
485	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	1.45
486	Microphthalmia, isolated 4	Enrichment	GDF6	1.45
487	Angel-shaped phalangoepiphyseal dysplasia	Enrichment	GDF5	1.45
488	Nail disorder, nonsyndromic congenital, 8	Enrichment	COL7A1	1.45
489	Hypereosinophilic syndrome, idiopathic	Enrichment	PDGFRA	1.45
490	Deafness, autosomal dominant 17	Enrichment	MYH9	1.45
491	Deafness, autosomal dominant 48	Enrichment	MYO1A	1.45
492	Glaucoma 1, open angle, h	Enrichment	EFEMP1	1.45
493	Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	Enrichment	RAC2	1.45
494	Deafness, autosomal recessive 39	Enrichment	HGF	1.45
495	Corneal dystrophy, posterior polymorphous, 2	Enrichment	COL8A2	1.45
496	Mastocytosis, cutaneous	Enrichment	KIT	1.45
497	Cardiomyopathy, familial hypertrophic, 8	Enrichment	MYL3	1.45
498	Cardiomyopathy, dilated, 1aa, with or without left ventricular noncompaction	Enrichment	ACTN2	1.45
499	Tubulointerstitial kidney disease, autosomal dominant 2	Enrichment	MUC1	1.45
500	Spinocerebellar ataxia 12	Enrichment	PPP2R2B	1.45
501	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	1.45
502	Intellectual developmental disorder, autosomal dominant 3	Enrichment	CDH15	1.45
503	Mitral valve prolapse 2	Enrichment	DCHS1	1.45
504	Marshall syndrome	Enrichment	COL11A1	1.45
505	Congenital myopathy 2a, typical, autosomal dominant	Enrichment	ACTA1	1.45
506	Kniest dysplasia	Enrichment	COL2A1	1.45
507	Apert syndrome	Enrichment	FGFR2	1.45
508	Neuroblastoma 3	Enrichment	ALK	1.45
509	Cardiomyopathy, dilated, 1jj	Enrichment	LAMA4	1.45
510	Deafness, autosomal dominant 22	Enrichment	MYO6	1.45
511	Transient bullous dermolysis of the newborn	Enrichment	COL7A1	1.45
512	Basal ganglia calcification, idiopathic, 5	Enrichment	PDGFB	1.45
513	Hyperpigmentation with or without hypopigmentation, familial progressive	Enrichment	KITLG	1.45
514	Corneal dystrophy, fuchs endothelial, 1	Enrichment	COL8A2	1.45
515	Platyspondylic lethal skeletal dysplasia, torrance type	Enrichment	COL2A1	1.45
516	Atelosteogenesis, type iii	Enrichment	FLNB	1.45
517	Prostate cancer, hereditary, 11	Enrichment	HNF1B	1.45
518	Atelosteogenesis, type i	Enrichment	FLNB	1.45
519	Epidermolysis bullosa with congenital localized absence of skin and deformity of nails	Enrichment	COL7A1	1.45
520	Myofibromatosis, infantile, 1	Enrichment	PDGFRB	1.45
521	Fibrochondrogenesis 1	Enrichment	COL11A1	1.45
522	Lipoid proteinosis of urbach and wiethe	Enrichment	ECM1	1.45
523	Thanatophoric dysplasia, type ii	Enrichment	FGFR3	1.45
524	Spondyloepiphyseal dysplasia, stanescu type	Enrichment	COL2A1	1.45
525	Fanconi renotubular syndrome 4 with maturity-onset diabetes of the young	Enrichment	HNF4A	1.45
526	Myopathy, scapulohumeroperoneal	Enrichment	ACTA1	1.45
527	Lethal congenital contracture syndrome 2	Enrichment	ERBB3	1.45
528	Lissencephaly 5	Enrichment	LAMB1	1.45
529	Weill-marchesani syndrome 2	Enrichment	FBN1	1.45
530	Cardiomyopathy, dilated, 1ee	Enrichment	MYH6	1.45
531	Hypogonadotropic hypogonadism 20 with or without anosmia	Enrichment	FGF17	1.45
532	Sick sinus syndrome 3	Enrichment	MYH6	1.45
533	Griscelli syndrome, type 1	Enrichment	MYO5A	1.45
534	Fetal encasement syndrome	Enrichment	CHUK	1.45
535	Retinitis pigmentosa 56	Enrichment	IMPG2	1.45
536	Ciliary dyskinesia, primary, 33	Enrichment	DRC4	1.45
537	Deafness, autosomal dominant 56	Enrichment	TNC	1.45
538	Elejalde neuroectodermal melanolysosomal syndrome	Enrichment	MYO5A	1.45
539	Gist-plus syndrome	Enrichment	PDGFRA	1.45
540	Camptodactyly, tall stature, and hearing loss syndrome	Enrichment	FGFR3	1.45
541	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	1.45
542	Hypogonadotropic hypogonadism 23 with or without anosmia	Enrichment	LHB	1.45
543	Geleophysic dysplasia 2	Enrichment	FBN1	1.45
544	Protrusio acetabuli	Enrichment	FBN1	1.45
545	Aplasia of lacrimal and salivary glands	Enrichment	FGF10	1.45
546	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	1.45
547	Acrogeria, gottron type	Enrichment	COL3A1	1.45
548	Epiphyseal dysplasia, multiple, 6	Enrichment	COL9A1	1.45
549	Weill-marchesani syndrome 3	Enrichment	LTBP2	1.45
550	Achondrogenesis, type ii	Enrichment	COL2A1	1.45
551	Ectodermal dysplasia 17 with or without limb malformations	Enrichment	LEF1	1.45
552	Megacystis-microcolon-intestinal hypoperistalsis syndrome 5	Enrichment	ACTG2	1.45
553	Visceral neuropathy, familial, 2, autosomal recessive	Enrichment	ERBB2	1.45
554	Teebi hypertelorism syndrome 2	Enrichment	CDH11	1.45
555	Noonan syndrome 13	Enrichment	MAPK1	1.45
556	Deafness, autosomal recessive 108	Enrichment	ROR1	1.45
557	Macular degeneration, early-onset	Enrichment	FBN2	1.45
558	Macular dystrophy, vitelliform, 4	Enrichment	IMPG1	1.45
559	Fraser syndrome 2	Enrichment	FREM2	1.45
560	Nephrotic syndrome, type 26	Enrichment	LAMA5	1.45
561	Myasthenic syndrome, congenital, 9, associated with acetylcholine receptor deficiency	Enrichment	MUSK	1.45
562	Developmental and epileptic encephalopathy 58	Enrichment	NTRK2	1.45
563	Multiple synostoses syndrome 4	Enrichment	GDF6	1.45
564	Myasthenic syndrome, congenital, 19	Enrichment	COL13A1	1.45
565	Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development	Enrichment	PTPA	1.45
566	Deafness, x-linked 6	Enrichment	COL4A6	1.45
567	Intellectual developmental disorder, x-linked 110	Enrichment	FGF13	1.45
568	Agammaglobulinemia 8b, autosomal recessive	Enrichment	TCF3	1.45
569	Spinocerebellar ataxia 27b, late-onset	Enrichment	FGF14	1.45
570	Venous malformations, multiple cutaneous and mucosal	Enrichment	TEK	1.45
571	Epiphyseal dysplasia, multiple, 2	Enrichment	COL9A2	1.45
572	Deafness, autosomal dominant 4a	Enrichment	MYH14	1.45
573	Terminal osseous dysplasia	Enrichment	FLNA	1.45
574	Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies	Enrichment	RAC3	1.45
575	Congenital myopathy 8	Enrichment	ACTN2	1.45
576	Ullrich congenital muscular dystrophy 1b	Enrichment	COL6A2	1.45
577	Hyperemesis gravidarum	Enrichment	GDF15	1.45
578	Cutis laxa, autosomal recessive, type id	Enrichment	EFEMP1	1.45
579	Amegakaryocytic thrombocytopenia, congenital, 2	Enrichment	THPO	1.45
580	Deafness, autosomal recessive 125	Enrichment	GAS2	1.45
581	Short syndrome	Enrichment	PIK3R1	1.45
582	Houge-janssens syndrome 4	Enrichment	PPP2R5C	1.45
583	Combined osteogenesis imperfecta and ehlers-danlos syndrome 2	Enrichment	COL1A2	1.45
584	Hereditary lymphedema id	Enrichment	VEGFC	1.45
585	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	1.45
586	Fg syndrome 2	Enrichment	FLNA	1.45
587	Osteofibrous dysplasia	Enrichment	MET	1.45
588	Complete cryptophthalmia	Enrichment	FREM2	1.45
589	Deafness, autosomal recessive 37	Enrichment	MYO6	1.45
590	Microphthalmia, syndromic 6	Enrichment	BMP4	1.45
591	Spondyloperipheral dysplasia	Enrichment	COL2A1	1.45
592	Myosclerosis, autosomal recessive	Enrichment	COL6A2	1.45
593	Porencephaly	Enrichment	COL4A1	1.45
594	Ullrich congenital muscular dystrophy 1c	Enrichment	COL6A3	1.45
595	Spondylometaepiphyseal dysplasia, short limb-hand type	Enrichment	DDR2	1.45
596	Deafness, autosomal dominant 37	Enrichment	COL11A1	1.45
597	Lymphoplasmacytic lymphoma	Enrichment	FBN1	1.45
598	Intellectual developmental disorder, x-linked 46	Enrichment	ARHGEF6	1.45
599	Diarrhea 15, congenital	Enrichment	MYO1A	1.45
600	Myeloid and lymphoid neoplasms associated with pdgfra rearrangement	Enrichment	PDGFRA	1.45
601	Agenesis of corpus callosum, cardiac, ocular, and genital syndrome	Enrichment	CDH2	1.45
602	Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia	Enrichment	RAC2	1.45
603	Developmental and epileptic encephalopathy 90	Enrichment	FGF13	1.45
604	Orofacial cleft 11	Enrichment	BMP4	1.45
605	Metacarpal 4-5 fusion	Enrichment	FGF16	1.45
606	Epiphyseal dysplasia, multiple, 3	Enrichment	COL9A3	1.45
607	Lymphatic malformation 4	Enrichment	VEGFC	1.45
608	Papillary tumor of the pineal region	Enrichment	PTEN	1.45
609	Atrial fibrillation, familial, 18	Enrichment	MYL4	1.45
610	Lacrimoauriculodentodigital syndrome 3	Enrichment	FGF10	1.45
611	Familial isolated trichomegaly	Enrichment	FGF5	1.45
612	Nemaline myopathy 7	Enrichment	CFL2	1.45
613	Houge-janssens syndrome 2	Enrichment	PPP2R1A	1.45
614	Spondyloepimetaphyseal dysplasia, aggrecan type	Enrichment	ACAN	1.45
615	Deafness, autosomal dominant 11	Enrichment	MYO7A	1.45
616	Deafness, autosomal dominant 13	Enrichment	COL11A2	1.45
617	Deafness, autosomal recessive 97	Enrichment	MET	1.45
618	Prostate cancer/brain cancer susceptibility	Enrichment	EPHB2	1.45
619	Microvascular complications of diabetes 1	Enrichment	VEGFA	1.45
620	Agammaglobulinemia 8a, autosomal dominant	Enrichment	TCF3	1.45
621	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	1.45
622	Skin/hair/eye pigmentation, variation in, 7	Enrichment	KITLG	1.45
623	Hypotrichosis	Enrichment	CDH3	1.45
624	Crouzon syndrome with acanthosis nigricans	Enrichment	FGFR3	1.45
625	Camurati-engelmann disease 2	Enrichment	TGFB2	1.45
626	Actn3 deficiency	Enrichment	ACTN3	1.45
627	Geleophysic dysplasia 3	Enrichment	LTBP3	1.45
628	Spondyloepiphyseal dysplasia, kimberley type	Enrichment	ACAN	1.45
629	Otopalatodigital syndrome spectrum disorder	Enrichment	FLNA	1.45
630	Epidermolysis bullosa pruriginosa	Enrichment	COL7A1	1.45
631	Deafness, autosomal recessive 30	Enrichment	MYO3A	1.45
632	Becker nevus syndrome	Enrichment	ACTB	1.45
633	Celiac disease 4	Enrichment	MYO9B	1.45
634	Dystonia-deafness syndrome 1	Enrichment	ACTB	1.45
635	Autism 9	Enrichment	MET	1.45
636	Stickler syndrome, type i, nonsyndromic ocular	Enrichment	COL2A1	1.45
637	Visceral neuropathy, familial, 3, autosomal dominant	Enrichment	ACTG2	1.45
638	Cardiomyopathy, familial hypertrophic, 14	Enrichment	MYH6	1.45
639	Arrhythmogenic right ventricular dysplasia, familial, 14	Enrichment	CDH2	1.45
640	Stickler syndrome, type iv	Enrichment	COL9A1	1.45
641	Glaucoma 1, open angle, o	Enrichment	NTF4	1.45
642	Cortical malformations, occipital	Enrichment	LAMC3	1.45
643	Iron overload	Enrichment	BMP6	1.45
644	Congenital myopathy 2b, severe infantile, autosomal recessive	Enrichment	ACTA1	1.45
645	Basal ganglia calcification, idiopathic, 4	Enrichment	PDGFRB	1.45
646	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	1.45
647	Hypogonadotropic hypogonadism 12 with or without anosmia	Enrichment	GNRH1	1.45
648	Multiple sclerosis 5	Enrichment	TNFRSF1A	1.45
649	Craniosynostosis 3	Enrichment	TCF12	1.45
650	Hypogonadotropic hypogonadism 16 with or without anosmia	Enrichment	SEMA3A	1.45
651	Leber congenital amaurosis 17	Enrichment	GDF6	1.45
652	Cowden syndrome 6	Enrichment	AKT1	1.45
653	Telangiectasia, hereditary hemorrhagic, type 5	Enrichment	GDF2	1.45
654	Amyotrophic lateral sclerosis 19	Enrichment	ERBB4	1.45
655	Muscular dystrophy, autosomal recessive, with cardiomyopathy and triangular tongue	Enrichment	LIMS2	1.45
656	Hereditary thrombocytosis with transverse limb defect	Enrichment	THPO	1.45
657	Bleeding disorder, platelet-type, 15	Enrichment	ACTN1	1.45
658	Peripheral neuropathy, myopathy, hoarseness, and hearing loss	Enrichment	MYH14	1.45
659	Nasopharyngeal carcinoma 3	Enrichment	MST1R	1.45
660	Fibrochondrogenesis 2	Enrichment	COL11A2	1.45
661	Dystonia 27	Enrichment	COL6A3	1.45
662	Achromatopsia 7	Enrichment	ATF6	1.45
663	Myeloid and lymphoid neoplasms associated with pdgfrb rearrangement	Enrichment	PDGFRB	1.45
664	Autosomal dominant familial visceral neuropathy	Enrichment	ACTG2	1.45
665	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	1.45
666	Thyroid gland disease	Enrichment	COL7A1	1.45
667	Acute myeloid leukemia with minimal differentiation	Enrichment	FLT3	1.45
668	Type 1 diabetes mellitus 20	Enrichment	HNF1A	1.45
669	Hypogonadotropic hypogonadism 6 with or without anosmia	Enrichment	FGF8	1.45
670	Obesity, hyperphagia, and developmental delay	Enrichment	NTRK2	1.45
671	Focal segmental glomerulosclerosis 6	Enrichment	MYO1E	1.45
672	Glioma susceptibility 2	Enrichment	PTEN	1.45
673	Corneal dystrophy, fuchs endothelial, 3	Enrichment	TCF4	1.45
674	Achondroplasia, severe, with developmental delay and acanthosis nigricans	Enrichment	FGFR3	1.45
675	Kosaki overgrowth syndrome	Enrichment	PDGFRB	1.45
676	Stickler syndrome, type v	Enrichment	COL9A2	1.45
677	Tumoral calcinosis, hyperphosphatemic, familial, 2	Enrichment	FGF23	1.45
678	Hartsfield syndrome	Enrichment	FGFR1	1.45
679	Congenital heart defects, multiple types, 7	Enrichment	FLT4	1.45
680	Loeys-dietz syndrome 5	Enrichment	TGFB3	1.45
681	Renal hypodysplasia/aplasia 2	Enrichment	FGF20	1.45
682	Macular dystrophy, vitelliform, 5	Enrichment	IMPG2	1.45
683	Tnf receptor-associated periodic fever syndrome	Enrichment	TNFRSF1A	1.45
684	Bleeding disorder, platelet-type, 22	Enrichment	EPHB2	1.45
685	20p12.3 microdeletion syndrome	Enrichment	BMP2	1.45
686	Cutis laxa, autosomal recessive, type iie	Enrichment	LTBP1	1.45
687	X-linked ehlers-danlos syndrome	Enrichment	FLNA	1.45
688	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	1.45
689	Takenouchi-kosaki syndrome	Enrichment	CDC42	1.45
690	Glaucoma 3, primary congenital, e	Enrichment	TEK	1.45
691	Congenital myopathy 2c, severe infantile, autosomal dominant	Enrichment	ACTA1	1.45
692	Bartsocas-papas syndrome 2	Enrichment	CHUK	1.45
693	Short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies 1	Enrichment	BMP2	1.45
694	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	1.45
695	Myopathy, distal, 6, adult-onset, autosomal dominant	Enrichment	ACTN2	1.45
696	Qualitative or quantitative defects of collagen 6	Enrichment	COL6A2	1.45
697	Deafness, autosomal dominant 90	Enrichment	MYO3A	1.45
698	Myasthenic syndrome, congenital, 24, presynaptic	Enrichment	MYO9A	1.45
699	Brain abnormalities, neurodegeneration, and dysosteosclerosis	Enrichment	CSF1R	1.45
700	Developmental and epileptic encephalopathy 47	Enrichment	FGF12	1.45
701	Ocular pterygium-digital keloid dysplasia syndrome	Enrichment	PDGFRB	1.45
702	Congenital myopathy 14	Enrichment	MYL1	1.45
703	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	1.45
704	Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia	Enrichment	RAC2	1.45
705	Chronic mast cell leukemia	Enrichment	KIT	1.45
706	Premature ovarian failure 14	Enrichment	GDF9	1.45
707	Warburg-cinotti syndrome	Enrichment	DDR2	1.45
708	Bent bone dysplasia syndrome 2	Enrichment	LAMA5	1.45
709	Vitreoretinopathy with phalangeal epiphyseal dysplasia	Enrichment	COL2A1	1.45
710	Recessive dystrophic epidermolysis bullosa-generalized other	Enrichment	COL7A1	1.45
711	Immunodeficiency 129	Enrichment	RHOH	1.45
712	Tufted angioma of skin	Enrichment	KDR	1.45
713	Developmental delay with variable intellectual impairment and behavioral abnormalities	Enrichment	TCF20	1.45
714	Asphyxia neonatorum	Enrichment	COL1A1	1.45
715	Deafness, autosomal dominant 69	Enrichment	KITLG	1.45
716	Bethlem myopathy 1b	Enrichment	COL6A2	1.45
717	Tsh producing pituitary tumor	Enrichment	CDH23	1.45
718	Attention deficit-hyperactivity disorder 8	Enrichment	CDH2	1.45
719	Thrombocytopenia 9	Enrichment	THPO	1.45
720	Fibrosis of extraocular muscles, congenital, 5	Enrichment	COL25A1	1.45
721	Adenoid ameloblastoma	Enrichment	CTNNB1	1.45
722	Arthrogryposis, distal, type 11	Enrichment	MET	1.45
723	Amelogenesis imperfecta, type ih	Enrichment	ITGB6	1.45
724	Lacrimoauriculodentodigital syndrome 2	Enrichment	FGFR3	1.45
725	Baraitser-winter syndrome	Enrichment	ACTB	1.45
726	Late-onset junctional epidermolysis bullosa	Enrichment	COL17A1	1.45
727	Csf1r-related disorder	Enrichment	CSF1R	1.45
728	Col4a1-related disorders	Enrichment	COL4A1	1.45
729	Occipital pachygyria and polymicrogyria	Enrichment	LAMC3	1.45
730	Short-rib thoracic dysplasia 22 without polydactyly	Enrichment	FGF4	1.45
731	Skin fragility-woolly hair-palmoplantar keratoderma syndrome	Enrichment	DSP	1.45
732	Usher syndrome type 1b	Enrichment	MYO7A	1.45
733	Bockenheimer syndrome	Enrichment	TEK	1.45
734	Bethlem myopathy 1c	Enrichment	COL6A3	1.45
735	Retinal lattice degeneration	Enrichment	COL9A3	1.45
736	T-cell immunodeficiency with epidermodysplasia verruciformis	Enrichment	RHOH	1.45
737	Capillary hemangioma	Enrichment	AKT3	1.45
738	Glaucoma secondary to spherophakia/ectopia lentis and megalocornea	Enrichment	LTBP2	1.45
739	Klippel-feil syndrome	Enrichment	MYO18B	1.45
740	Flnb-related disorders	Enrichment	FLNB	1.45
741	Breast lobular carcinoma	Enrichment	CDH1	1.45
742	Hyperinsulinism due to hnf4a deficiency	Enrichment	HNF4A	1.45
743	Anus disease	Enrichment	FREM2	1.45
744	Isolated bone marrow mastocytosis	Enrichment	KIT	1.45
745	Autosomal dominant nonsyndromic hearing loss 17	Enrichment	MYH9	1.45
746	Autosomal dominant rhegmatogenous retinal detachment	Enrichment	COL2A1	1.45
747	Smoldering systemic mastocytosis	Enrichment	KIT	1.45
748	Progressive sensorineural hearing loss-hypertrophic cardiomyopathy syndrome	Enrichment	MYO6	1.45
749	Col4a1 or col4a2-related cerebral small vessel disease	Enrichment	COL4A1	1.45
750	Multiple epiphyseal dysplasia with myopia and deafness	Enrichment	COL2A1	1.45
751	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	1.45
752	Alk-positive anaplastic large cell lymphoma	Enrichment	ALK	1.45
753	Zebra body myopathy	Enrichment	ACTA1	1.45
754	Spinocerebellar ataxia type 27b	Enrichment	FGF14	1.45
755	Hypochondrogenesis	Enrichment	COL2A1	1.45
756	Infantile lad-like disease due to rac2 deficiency	Enrichment	RAC2	1.45
757	Fgfr3-related chondrodysplasia	Enrichment	FGFR3	1.45
758	Congenital smooth muscle hamartoma	Enrichment	ACTB	1.45
759	X-linked alport syndrome	Enrichment	COL4A5	1.45
760	Pneumothorax	Enrichment	COL5A1	1.45
761	Reticular dysgenesis-like severe combined immunodeficiency	Enrichment	RAC2	1.45
762	Nocarh syndrome	Enrichment	CDC42	1.45
763	Autosomal recessive limb-girdle muscular dystrophy type 2w	Enrichment	LIMS2	1.45
764	Mastocytosis	Enrichment	KIT	1.45
765	Congenital primary lymphedema of gordon	Enrichment	VEGFC	1.45
766	Aplasia cutis-enamel dysplasia syndrome	Enrichment	FOSL2	1.45
767	Localized dystrophic epidermolysis bullosa, acral form	Enrichment	COL7A1	1.45
768	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	1.45
769	Osteochondritis dissecans	Enrichment	ACAN	1.45
770	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	1.45
771	Camptodactyly-tall stature-scoliosis-hearing loss syndrome	Enrichment	FGFR3	1.45
772	Autosomal dominant myopia-midfacial retrusion-sensorineural hearing loss-rhizomelic dysplasia syndrome	Enrichment	COL11A1	1.45
773	Autosomal dominant nonsyndromic hearing loss 22	Enrichment	MYO6	1.45
774	Familial progressive hyperpigmentation	Enrichment	KITLG	1.45
775	Dysspondyloenchondromatosis	Enrichment	COL2A1	1.45
776	Cystic lymphangioma	Enrichment	COL11A2	1.45
777	Early-onset calcifying leukoencephalopathy-skeletal dysplasia	Enrichment	CSF1R	1.45
778	Hypogonadotropic hypogonadism 26 with or without anosmia	Enrichment	TCF12	1.45
779	Abdominal aortic aneurysm	Enrichment	COL3A1	1.45
780	Cutaneous mastocytoma	Enrichment	KIT	1.45
781	Lethal arteriopathy syndrome due to fibulin-4 deficiency	Enrichment	EFEMP2	1.45
782	Neonatal marfan syndrome	Enrichment	FBN1	1.45
783	Recessive dystrophic epidermolysis bullosa inversa	Enrichment	COL7A1	1.45
784	X-linked keloid scarring-reduced joint mobility-increased optic cup-to-disc ratio syndrome	Enrichment	FLNA	1.45
785	Typical urticaria pigmentosa	Enrichment	KIT	1.45
786	Medullary sponge kidney	Enrichment	HNF1B	1.45
787	Ppp2r1a-related neurodevelopmental disorder	Enrichment	PPP2R1A	1.45
788	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	1.45
789	Actin-accumulation myopathy	Enrichment	ACTA1	1.45
790	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	1.45
791	Nodular urticaria pigmentosa	Enrichment	KIT	1.45
792	Renal dysplasia, bilateral	Enrichment	HNF1B	1.45
793	Premature aging	Enrichment	VIM	1.45
794	Unilateral multicystic dysplastic kidney	Enrichment	HNF1B	1.45
795	Type 2 collagen-related bone disorder	Enrichment	COL2A1	1.45
796	Hartsfield-bixler-demyer syndrome	Enrichment	FGFR1	1.45
797	Alk-positive large b-cell lymphoma	Enrichment	ALK	1.45
798	Pseudoxanthomatous diffuse cutaneous mastocytosis	Enrichment	KIT	1.45
799	Lama5-related multisystemic syndrome	Enrichment	LAMA5	1.45
800	Renal dysplasia, unilateral	Enrichment	HNF1B	1.45
801	Telangiectasia macularis eruptiva perstans	Enrichment	KIT	1.45
802	Acute mast cell leukemia	Enrichment	KIT	1.45
803	Myopathic intestinal pseudoobstruction	Enrichment	ACTG2	1.45
804	Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome	Enrichment	RAC2	1.45
805	Short stature-advanced bone age-early-onset osteoarthritis syndrome	Enrichment	ACAN	1.45
806	Cryptophthalmia	Enrichment	FREM2	1.45
807	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	1.45
808	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	1.45
809	Familial progressive hyper- and hypopigmentation	Enrichment	KITLG	1.45
810	Plaque-form urticaria pigmentosa	Enrichment	KIT	1.45
811	Interstitial lung disease specific to childhood	Enrichment	FGF10	1.45
812	Serous carcinoma of the corpus uteri	Enrichment	ERBB2	1.45
813	Ephb4-related lymphatic-related hydrops fetalis	Enrichment	EPHB4	1.45
814	Generalized dominant dystrophic epidermolysis bullosa	Enrichment	COL7A1	1.45
815	Bullous diffuse cutaneous mastocytosis	Enrichment	KIT	1.45
816	Microcystic stromal tumor	Enrichment	CTNNB1	1.45
817	Temporomandibular joint anomaly	Enrichment	DOCK1	1.45
818	Actg2 visceral myopathy	Enrichment	ACTG2	1.45
819	Vein of galen aneurysmal malformation	Enrichment	EPHB4	1.45
820	Laminin subunit alpha 2-related muscular dystrophy	Enrichment	LAMA2	1.45
821	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	1.45
822	Testis seminoma	Enrichment	KIT	1.45
823	Brugada syndrome 1	Enrichment	CACNA2D1, FBN1	1.44
824	Focal segmental glomerulosclerosis	Enrichment	COL4A4, COL4A5, PLCE1	1.44
825	Hypocalciuric hypercalcemia, familial, type ii	Enrichment	GNA11	1.43
826	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	1.43
827	Cardiospondylocarpofacial syndrome	Enrichment	MAP3K7	1.43
828	Coffin-lowry syndrome	Enrichment	RPS6KA3	1.43
829	Oculoectodermal syndrome	Enrichment	KRAS	1.43
830	Intellectual developmental disorder, x-linked 30	Enrichment	PAK3	1.43
831	Pallister-killian syndrome	Enrichment	ARAF	1.43
832	Type 1 diabetes mellitus 10	Enrichment	IL2RA	1.43
833	Noonan syndrome 5	Enrichment	RAF1	1.43
834	Noonan syndrome 4	Enrichment	SOS1	1.43
835	Pseudohypoparathyroidism, type ic	Enrichment	GNAS	1.43
836	Leprosy 4	Enrichment	LTA	1.43
837	Carney complex, type 1	Enrichment	PRKAR1A	1.43
838	Melorheostosis, isolated	Enrichment	MAP2K1	1.43
839	Osseous heteroplasia, progressive	Enrichment	GNAS	1.43
840	Noonan syndrome 7	Enrichment	BRAF	1.43
841	Leopard syndrome 3	Enrichment	BRAF	1.43
842	Nail disorder, nonsyndromic congenital, 3	Enrichment	PLCD1	1.43
843	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	1.43
844	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	1.43
845	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	1.43
846	Melanosis, neurocutaneous	Enrichment	NRAS	1.43
847	Noonan syndrome 9	Enrichment	SOS2	1.43
848	Dyskinesia with orofacial involvement, autosomal dominant	Enrichment	ADCY5	1.43
849	Noonan syndrome 6	Enrichment	NRAS	1.43
850	Neurodevelopmental disorder with involuntary movements	Enrichment	GNAO1	1.43
851	Deafness, autosomal recessive 44	Enrichment	ADCY1	1.43
852	Frontometaphyseal dysplasia 2	Enrichment	MAP3K7	1.43
853	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	1.43
854	Ventricular tachycardia, familial	Enrichment	GNAI2	1.43
855	Acth-independent macronodular adrenal hyperplasia 1	Enrichment	GNAS	1.43
856	Noonan syndrome 11	Enrichment	MRAS	1.43
857	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	1.43
858	Pseudo-torch syndrome 3	Enrichment	STAT2	1.43
859	Spondylometaphyseal dysplasia with corneal dystrophy	Enrichment	PLCB3	1.43
860	Growth hormone insensitivity syndrome with immune dysregulation 2, autosomal dominant	Enrichment	STAT5B	1.43
861	Neurodevelopmental disorder with hyperkinetic movements and dyskinesia	Enrichment	ADCY5	1.43
862	Hyper-ige syndrome 6, autosomal dominant, with recurrent infections	Enrichment	STAT6	1.43
863	Pituitary adenoma 3, multiple types	Enrichment	GNAS	1.43
864	Knobloch syndrome 2	Enrichment	PAK2	1.43
865	Disabling pansclerotic morphea of childhood	Enrichment	STAT4	1.43
866	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	1.43
867	Bone marrow failure syndrome 5	Enrichment	TP53	1.43
868	Fetomaternal alloimmune thrombocytopenia 2	Enrichment	ITGA2B	1.43
869	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	1.43
870	Papilloma of choroid plexus	Enrichment	TP53	1.43
871	Pseudohypoaldosteronism, type iic	Enrichment	WNK1	1.43
872	Auriculocondylar syndrome 2a	Enrichment	PLCB4	1.43
873	Basal cell carcinoma 7	Enrichment	TP53	1.43
874	Intellectual developmental disorder, x-linked 19	Enrichment	RPS6KA3	1.43
875	Anaplastic thyroid carcinoma	Enrichment	TP53	1.43
876	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	1.43
877	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	1.43
878	Systemic lupus erythematosus 11	Enrichment	STAT4	1.43
879	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	1.43
880	Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities	Enrichment	GNAI1	1.43
881	Myxoma, intracardiac	Enrichment	PRKAR1A	1.43
882	Chronic recurrent multifocal osteomyelitis 3	Enrichment	IL1R1	1.43
883	Asthma-related traits 5	Enrichment	IRAK3	1.43
884	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	1.43
885	Developmental and epileptic encephalopathy 17	Enrichment	GNAO1	1.43
886	Dyskinesia with orofacial involvement, autosomal recessive	Enrichment	ADCY5	1.43
887	Cardiomyopathy, dilated, 1w	Enrichment	VCL	1.43
888	Lymphangioma	Enrichment	BRAF	1.43
889	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	1.43
890	Coronary artery disease, autosomal dominant, 1	Enrichment	MEF2A	1.43
891	Phace association	Enrichment	BRAF	1.43
892	Spinocerebellar ataxia 14	Enrichment	PRKCG	1.43
893	Melorheostosis	Enrichment	MAP2K1	1.43
894	Immunodeficiency 67	Enrichment	IRAK4	1.43
895	Night blindness, congenital stationary, autosomal dominant 3	Enrichment	GNAT1	1.43
896	Leopard syndrome 2	Enrichment	RAF1	1.43
897	Cardiomyopathy, familial hypertrophic, 15	Enrichment	VCL	1.43
898	Immunodeficiency 31a	Enrichment	STAT1	1.43
899	Dystonia 25	Enrichment	GNAL	1.43
900	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	1.43
901	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	1.43
902	Thrombocytopenia 11 with multiple congenital anomalies and dysmorphic facies	Enrichment	RAP1B	1.43
903	Night blindness, congenital stationary, type 1g	Enrichment	GNAT1	1.43
904	Hypocalcemia, autosomal dominant 2	Enrichment	GNA11	1.43
905	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	1.43
906	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	1.43
907	Immunodeficiency 31b	Enrichment	STAT1	1.43
908	Disorders of gnas inactivation	Enrichment	GNAS	1.43
909	Ductal carcinoma in situ	Enrichment	TP53	1.43
910	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	1.43
911	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	1.43
912	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	1.43
913	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	1.43
914	Thrombocytopenia 6	Enrichment	SRC	1.43
915	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	1.43
916	Sick sinus syndrome 4	Enrichment	GNB2	1.43
917	Autoinflammation with episodic fever and lymphadenopathy	Enrichment	RIPK1	1.43
918	Trigonitis	Enrichment	RAF1	1.43
919	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	1.43
920	Auriculocondylar syndrome 2b	Enrichment	PLCB4	1.43
921	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	1.43
922	Symptomatic form of coffin-lowry syndrome in female carriers	Enrichment	RPS6KA3	1.43
923	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	1.43
924	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	1.43
925	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	1.43
926	5q14.3 microdeletion syndrome	Enrichment	MEF2C	1.43
927	Congenital pulmonary airway malformation	Enrichment	KRAS	1.43
928	Cerebral cavernous malformations 5	Enrichment	MAP3K3	1.43
929	Choroid plexus cancer	Enrichment	TP53	1.43
930	Fetomaternal alloimmune thrombocytopenia 3	Enrichment	ITGA2	1.43
931	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	1.43
932	Capillary leak syndrome	Enrichment	TLN1	1.43
933	Syringocystadenoma papilliferum	Enrichment	BRAF	1.43
934	Pleomorphic xanthoastrocytoma	Enrichment	TP53	1.43
935	Ganglioglioma	Enrichment	BRAF	1.43
936	Nongerminomatous germ cell tumor	Enrichment	BRAF	1.43
937	Monostotic fibrous dysplasia	Enrichment	GNAS	1.43
938	Phace syndrome	Enrichment	BRAF	1.43
939	Gnao1-related disorder	Enrichment	GNAO1	1.43
940	Phakomatosis pigmentokeratotica	Enrichment	HRAS	1.43
941	Mef2c-related disorder	Enrichment	MEF2C	1.43
942	Classic hairy cell leukemia	Enrichment	BRAF	1.43
943	Phakomatosis cesiomarmorata	Enrichment	GNA11	1.43
944	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	1.43
945	Verrucous hemangioma	Enrichment	MAP3K3	1.43
946	Kaposiform hemangioendothelioma	Enrichment	GNA14	1.43
947	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	1.43
948	Mazabraud syndrome	Enrichment	GNAS	1.43
949	Neurocutaneous melanocytosis	Enrichment	NRAS	1.43
950	Cowden syndrome	Enrichment	AKT1, PTEN	1.42
951	Familial isolated arrhythmogenic right ventricular dysplasia	Enrichment	DSP, MYH7	1.42
952	Familial isolated dilated cardiomyopathy	Enrichment	ACTN2, DSP, LAMA4, MYH6, MYH7	1.41
953	Aortic valve disease 1	Enrichment	NOTCH1, SOS1, TAB2	1.41
954	Osteogenesis imperfecta, type iv	Enrichment	COL1A1, COL1A2, WNT1	1.41
955	Alzheimer's disease	Enrichment	CSF1R, PSEN1, TNF	1.41
956	Developmental and epileptic encephalopathy 8	Enrichment	ARHGEF9	1.40
957	Immunodeficiency 50	Enrichment	MSN	1.40
958	Deafness, autosomal recessive 24	Enrichment	RDX	1.40
959	Cardiac valvular dysplasia 1	Enrichment	PLD1	1.40
960	Lichtenstein-knorr syndrome	Enrichment	SLC9A1	1.40
961	Nephrotic syndrome, type 8	Enrichment	ARHGDIA	1.40
962	Wiskott-aldrich syndrome 2	Enrichment	WIPF1	1.40
963	Scapuloperoneal syndrome, neurogenic, kaeser type	Enrichment	DES	1.40
964	Immunodeficiency 62	Enrichment	ARHGEF1	1.40
965	Angioedema, hereditary, 5	Enrichment	ANGPT1	1.40
966	Neurodevelopmental disorder with absent language and variable seizures	Enrichment	WASF1	1.40
967	Neurodevelopmental disorder with midbrain and hindbrain malformations	Enrichment	ARHGEF2	1.40
968	Lymphoproliferative syndrome 3	Enrichment	CD70	1.40
969	Immunodeficiency with hyper-igm, type 1	Enrichment	CD40LG	1.40
970	Immunodeficiency 130 with hpv-related verrucosis	Enrichment	IL7	1.40
971	Ovarian dysgenesis 2	Enrichment	BMP15	1.40
972	Graft-versus-host disease	Enrichment	IL10	1.40
973	Isolated growth hormone deficiency type iii	Enrichment	BTK	1.40
974	Spermatogenic failure 99	Enrichment	SEPTIN4	1.40
975	Amyotrophic neuralgia	Enrichment	SEPTIN9	1.40
976	Allergic rhinitis	Enrichment	IL13	1.40
977	Slowed nerve conduction velocity, autosomal dominant	Enrichment	ARHGEF10	1.40
978	Auditory neuropathy, autosomal dominant 1	Enrichment	DIAPH3	1.40
979	Immunodeficiency 29	Enrichment	IL12B	1.40
980	Brain small vessel disease 5 with osteoporosis	Enrichment	ARHGEF15	1.40
981	Immature teratoma of ovary	Enrichment	BMP15	1.40
982	Cd40 ligand deficiency	Enrichment	CD40LG	1.40
983	Common variable immunodeficiency phenotype due to tweak deficiency	Enrichment	TNFSF12	1.40
984	Fetal akinesia deformation sequence 1	Enrichment	ACTA1, FBN2, MUSK, ROR2	1.39
985	Inflammatory bowel disease 1	Enrichment	IL6, PRKCQ	1.38
986	Renal agenesis, bilateral	Enrichment	FGF20, ITGA8	1.38
987	Thyrotoxic periodic paralysis 1	Enrichment	CACNA1S	1.35
988	Epilepsy, idiopathic generalized 9	Enrichment	CACNB4	1.35
989	Brugada syndrome 4	Enrichment	CACNB2	1.35
990	Episodic ataxia, type 5	Enrichment	CACNB4	1.35
991	Cerebellofaciodental syndrome	Enrichment	BRF1	1.35
992	Vitreoretinopathy, neovascular inflammatory	Enrichment	CAPN5	1.35
993	Neurodevelopmental disorder with speech impairment and with or without seizures	Enrichment	CACNA1I	1.35
994	Congenital myopathy 18	Enrichment	CACNA1S	1.35
995	Pulmonary hypertension, primary, 6	Enrichment	CAPNS1	1.35
996	Immunodeficiency 48	Enrichment	ZAP70	1.35
997	Cone-rod dystrophy, x-linked, 3	Enrichment	CACNA1F	1.35
998	Retinal cone dystrophy 4	Enrichment	CACNA2D4	1.35
999	Immunodeficiency 18	Enrichment	CD3E	1.35
1000	Primary aldosteronism, seizures, and neurologic abnormalities	Enrichment	CACNA1D	1.35
1001	Immunodeficiency 25	Enrichment	CD247	1.35
1002	Brugada syndrome 3	Enrichment	CACNA1C	1.35
1003	Epilepsy, childhood absence 6	Enrichment	CACNA1H	1.35
1004	Malignant hyperthermia 5	Enrichment	CACNA1S	1.35
1005	Ovarian dysgenesis 8	Enrichment	ESR2	1.35
1006	Intellectual developmental disorder, autosomal dominant 10	Enrichment	CACNG2	1.35
1007	Sinoatrial node dysfunction and deafness	Enrichment	CACNA1D	1.35
1008	Polydactyly-macrocephaly syndrome	Enrichment	MAX	1.35
1009	Spinocerebellar ataxia 42	Enrichment	CACNA1G	1.35
1010	Developmental and epileptic encephalopathy 110	Enrichment	CACNA2D1	1.35
1011	Autoimmune disease, multisystem, infantile-onset, 2	Enrichment	ZAP70	1.35
1012	Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits	Enrichment	CACNA1G	1.35
1013	Developmental and epileptic encephalopathy 69	Enrichment	CACNA1E	1.35
1014	Bryant-li-bhoj neurodevelopmental syndrome 1	Enrichment	H3-3A	1.35
1015	Hyperaldosteronism, familial, type iv	Enrichment	CACNA1H	1.35
1016	Polycystic ovary syndrome	Enrichment	CAPN10	1.35
1017	Immunodeficiency 19, severe combined	Enrichment	CD3D	1.35
1018	Conn's syndrome	Enrichment	CACNA1H	1.35
1019	Inner ear disease	Enrichment	BRF1	1.35
1020	Progressive muscular atrophy	Enrichment	CAPN3	1.35
1021	Sporadic hemiplegic migraine	Enrichment	CACNA1A	1.35
1022	Atypical timothy syndrome	Enrichment	CACNA1C	1.35
1023	Aldosterone-producing adenoma with seizures and neurological abnormalities	Enrichment	CACNA1D	1.35
1024	Immunodeficiency 19	Enrichment	CD3D	1.35
1025	Timothy syndrome type 2	Enrichment	CACNA1C	1.35
1026	Qualitative or quantitative defects of calpain	Enrichment	CAPN3	1.35
1027	Periodic paralysis with transient compartment-like syndrome	Enrichment	CACNA1S	1.35
1028	Timothy syndrome type 1	Enrichment	CACNA1C	1.35
1029	Zap70-related severe combined immunodeficiency	Enrichment	ZAP70	1.35
1030	Cacna1c-related disorders	Enrichment	CACNA1C	1.35
1031	Benign paroxysmal torticollis of infancy	Enrichment	CACNA1A	1.35
1032	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ABL1, CDKN2A, FLT3, MYC	1.34
1033	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	1.34
1034	Wilms tumor 5	Enrichment	BRAF, CHEK2	1.34
1035	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	1.34
1036	Chronic mucocutaneous candidiasis	Enrichment	IL17RA, IL17RC	1.34
1037	Limited scleroderma	Enrichment	CCN2, CCR6	1.34
1038	Cleft lip with or without cleft palate	Enrichment	CDH1, CTNND1	1.34
1039	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1, TCF3	1.33
1040	Congenital muscular dystrophy	Enrichment	CAPN3, LAMA2	1.33
1041	Pheochromocytoma	Enrichment	MAX, NF1, VHL	1.32
1042	Achromatopsia	Enrichment	ATF6, GNAT2	1.29
1043	Usher syndrome type 2	Enrichment	CDH23, MYO7A	1.25
1044	Polydactyly, postaxial, type a1	Enrichment	EP300, GLI1, PTCH1	1.24
1045	Wilms tumor 1	Enrichment	BRAF, CHEK2, IGF2	1.24
1046	Hydrocephalus	Enrichment	FGFR2, FZD3, PDGFRB	1.24
1047	Lynch syndrome	Enrichment	CHEK2, KRAS, TGFBR2	1.24
1048	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	CACNA1C, RAC1	1.23
1049	Amyloidosis, primary localized cutaneous, 1	Enrichment	OSMR	1.22
1050	Palmoplantar keratoderma, punctate type ii	Enrichment	BRCA1	1.22
1051	Immune deficiency, familial variable	Enrichment	TNFRSF13B	1.22
1052	Endosteal hyperostosis, autosomal dominant	Enrichment	LRP5	1.22
1053	Nail disorder, nonsyndromic congenital, 1	Enrichment	FZD6	1.22
1054	Cystic angiomatosis of bone, diffuse	Enrichment	RASA1	1.22
1055	Hypotrichosis-lymphedema-telangiectasia-renal defect syndrome	Enrichment	SOX18	1.22
1056	46,xy sex reversal 7	Enrichment	DHH	1.22
1057	Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement	Enrichment	TUBB3	1.22
1058	Panhypopituitarism, x-linked	Enrichment	SOX3	1.22
1059	Surfactant metabolism dysfunction, pulmonary, 4	Enrichment	CSF2RA	1.22
1060	Bone mineral density quantitative trait locus 1	Enrichment	LRP5	1.22
1061	Exudative vitreoretinopathy 4	Enrichment	LRP5	1.22
1062	Curry-jones syndrome	Enrichment	SMO	1.22
1063	Hypotrichosis-lymphedema-telangiectasia syndrome	Enrichment	SOX18	1.22
1064	Deafness, autosomal recessive 26	Enrichment	GAB1	1.22
1065	Telangiectasia, hereditary hemorrhagic, type 2	Enrichment	ACVRL1	1.22
1066	Osteopetrosis, autosomal recessive 7	Enrichment	TNFRSF11A	1.22
1067	Caspase 8 deficiency	Enrichment	CASP8	1.22
1068	Macular dystrophy, patterned, 2	Enrichment	CTNNA1	1.22
1069	Melanoma, cutaneous malignant 3	Enrichment	CDK4	1.22
1070	Schilbach-rott syndrome	Enrichment	PTCH1	1.22
1071	Polyposis syndrome, hereditary mixed, 2	Enrichment	BMPR1A	1.22
1072	Acromesomelic dysplasia 3	Enrichment	BMPR1B	1.22
1073	Immunodeficiency 30	Enrichment	IL12RB1	1.22
1074	Omodysplasia 2	Enrichment	FZD2	1.22
1075	Hajdu-cheney syndrome	Enrichment	NOTCH2	1.22
1076	Alagille syndrome 2	Enrichment	NOTCH2	1.22
1077	Acne inversa, familial, 1	Enrichment	NCSTN	1.22
1078	Immunodeficiency 16	Enrichment	TNFRSF4	1.22
1079	Polydactyly, preaxial i	Enrichment	GLI1	1.22
1080	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3	Enrichment	CCND2	1.22
1081	Lateral meningocele syndrome	Enrichment	NOTCH3	1.22
1082	Polycystic lung disease	Enrichment	CCR2	1.22
1083	Seckel syndrome 1	Enrichment	ATR	1.22
1084	Microcephaly 12, primary, autosomal recessive	Enrichment	CDK6	1.22
1085	Mirror movements 2	Enrichment	RAD51	1.22
1086	Tooth agenesis, selective, 7	Enrichment	LRP6	1.22
1087	Lamb-shaffer syndrome	Enrichment	SOX5	1.22
1088	Bleeding disorder, platelet-type, 18	Enrichment	RASGRP2	1.22
1089	Macrothrombocytopenia, isolated, 1, autosomal dominant	Enrichment	TUBB1	1.22
1090	Caudal duplication anomaly	Enrichment	AXIN1	1.22
1091	Vesicoureteral reflux 3	Enrichment	SOX17	1.22
1092	Brachydactyly, type a1, d	Enrichment	BMPR1B	1.22
1093	Whim syndrome 1	Enrichment	CXCR4	1.22
1094	Accelerated tumor formation	Enrichment	MDM2	1.22
1095	Arrhythmogenic right ventricular dysplasia, familial, 13	Enrichment	CTNNA3	1.22
1096	Craniosynostosis and dental anomalies	Enrichment	IL11RA	1.22
1097	Hiatt-neu-cooper neurodevelopmental syndrome	Enrichment	RALA	1.22
1098	Exudative vitreoretinopathy 8	Enrichment	LRP6	1.22
1099	Immunodeficiency 64 with lymphoproliferation	Enrichment	RASGRP1	1.22
1100	Intellectual developmental disorder with speech delay and dysmorphic facies	Enrichment	SOX4	1.22
1101	Fanconi anemia, complementation group r	Enrichment	RAD51	1.22
1102	46,xy sex reversal 10	Enrichment	SOX9	1.22
1103	Polydactyly, postaxial, type a8	Enrichment	GLI1	1.22
1104	Joubert syndrome 32	Enrichment	SUFU	1.22
1105	Intellectual developmental disorder, autosomal recessive 63	Enrichment	CAMK2A	1.22
1106	Immunodeficiency 63 with lymphoproliferation and autoimmunity	Enrichment	IL2RB	1.22
1107	Intellectual developmental disorder, autosomal dominant 54	Enrichment	CAMK2B	1.22
1108	Cortical dysplasia, complex, with other brain malformations 9	Enrichment	CTNNA2	1.22
1109	Lessel-kubisch syndrome	Enrichment	MDM2	1.22
1110	Tolchin-le caignec syndrome	Enrichment	SOX6	1.22
1111	46,xx sex reversal 2	Enrichment	SOX9	1.22
1112	Okt4 epitope deficiency	Enrichment	CD4	1.22
1113	Intellectual developmental disorder, x-linked, with panhypopituitarism	Enrichment	SOX3	1.22
1114	Cardiomyopathy, familial hypertrophic, 6	Enrichment	PRKAG2	1.22
1115	Infant-type hemispheric glioma	Enrichment	BRCA1	1.22
1116	Cardiomyopathy, dilated, 1v	Enrichment	PSEN2	1.22
1117	Osteoporosis-pseudoglioma syndrome	Enrichment	LRP5	1.22
1118	Glycogen storage disease of heart, lethal congenital	Enrichment	PRKAG2	1.22
1119	Coronary artery disease, autosomal dominant 2	Enrichment	LRP6	1.22
1120	Bone mineral density quantitative trait locus 16	Enrichment	WNT1	1.22
1121	Immunoglobulin a deficiency 2	Enrichment	TNFRSF13B	1.22
1122	Tumor predisposition syndrome 4	Enrichment	CHEK2	1.22
1123	Psoriasis 7	Enrichment	IL23R	1.22
1124	Thrombocytopenia 4	Enrichment	CYCS	1.22
1125	Autoimmune lymphoproliferative syndrome, type iia	Enrichment	CASP10	1.22
1126	Acrocapitofemoral dysplasia	Enrichment	IHH	1.22
1127	Polycystic liver disease 4 with or without kidney cysts	Enrichment	LRP5	1.22
1128	Immunodeficiency with hyper-igm, type 3	Enrichment	CD40	1.22
1129	Neuroendocrine tumor	Enrichment	CDKN1B	1.22
1130	Colorectal cancer, hereditary nonpolyposis, type 6	Enrichment	TGFBR2	1.22
1131	Cortical dysplasia, complex, with other brain malformations 7	Enrichment	TUBB2B	1.22
1132	Cardiomyopathy, dilated, 1u	Enrichment	PSEN1	1.22
1133	Cutaneous telangiectasia and cancer syndrome, familial	Enrichment	ATR	1.22
1134	Interleukin 6, serum level of, quantitative trait locus	Enrichment	IL6R	1.22
1135	Surfactant metabolism dysfunction, pulmonary, 5	Enrichment	CSF2RB	1.22
1136	Immunodeficiency 26 with or without neurologic abnormalities	Enrichment	PRKDC	1.22
1137	Soluble interleukin-6 receptor, serum level of, quantitative trait locus	Enrichment	IL6R	1.22
1138	Immunodeficiency 90 with encephalopathy, functional hyposplenia, and hepatic dysfunction	Enrichment	FADD	1.22
1139	Pulmonary hypertension, primary, 2	Enrichment	SMAD9	1.22
1140	Hyper-ige syndrome 5, autosomal recessive, with recurrent infections	Enrichment	IL6R	1.22
1141	Oocyte/zygote/embryo maturation arrest 23	Enrichment	TUBA4A	1.22
1142	Microphthalmia, syndromic 12	Enrichment	RARB	1.22
1143	Myofibromatosis, infantile, 2	Enrichment	NOTCH3	1.22
1144	Frontotemporal dementia and/or amyotrophic lateral sclerosis 9	Enrichment	TUBA4A	1.22
1145	Candidiasis, familial, 9	Enrichment	IL17RC	1.22
1146	Loeys-dietz syndrome 6	Enrichment	SMAD2	1.22
1147	Inflammatory bowel disease 17	Enrichment	IL23R	1.22
1148	Microphthalmia/coloboma 11	Enrichment	FZD5	1.22
1149	Immunodeficiency 97 with autoinflammation	Enrichment	PIK3CG	1.22
1150	Acne inversa, familial, 2, with or without dowling-degos disease	Enrichment	PSENEN	1.22
1151	Endometrial serous adenocarcinoma	Enrichment	ATM	1.22
1152	Type 1 diabetes mellitus 22	Enrichment	CCR5	1.22
1153	Immunodeficiency 123 with hpv-related verrucosis	Enrichment	CD28	1.22
1154	Acne inversa, familial, 3	Enrichment	PSEN1	1.22
1155	Macular degeneration, age-related, 12	Enrichment	CX3CR1	1.22
1156	Skeletal muscle glycogen content and metabolism quantitative trait locus	Enrichment	PRKAG3	1.22
1157	Intellectual developmental disorder with microcephaly and with or without ocular malformations or hypogonadotropic hypogonadism	Enrichment	SOX11	1.22
1158	Psoriasis	Enrichment	IL17RA	1.22
1159	Facial palsy, congenital, with ptosis and velopharyngeal dysfunction	Enrichment	TUBB6	1.22
1160	Menke-hennekam syndrome 1	Enrichment	CREBBP	1.22
1161	Leiomyosarcoma	Enrichment	CHEK2	1.22
1162	Immunodeficiency 79	Enrichment	CD4	1.22
1163	Intellectual developmental disorder, autosomal dominant 53	Enrichment	CAMK2A	1.22
1164	Ciliary dyskinesia, primary, 46	Enrichment	STK36	1.22
1165	Telangiectasis	Enrichment	ACVRL1	1.22
1166	Craniometadiaphyseal osteosclerosis with hip dysplasia	Enrichment	AXIN1	1.22
1167	Whim syndrome 2	Enrichment	CXCR2	1.22
1168	Intellectual developmental disorder, autosomal dominant 59	Enrichment	CAMK2G	1.22
1169	Trilateral retinoblastoma	Enrichment	RB1	1.22
1170	Plexiform neurofibroma	Enrichment	NF1	1.22
1171	Congenital heart defects, multiple types, 8, with or without heterotaxy	Enrichment	SMAD2	1.22
1172	Macrothrombocytopenia, isolated, 2, autosomal dominant	Enrichment	TUBA8	1.22
1173	T-b+ severe combined immunodeficiency due to jak3 deficiency	Enrichment	JAK3	1.22
1174	Neurofibroma	Enrichment	NF1	1.22
1175	Cdkn2a cancer predisposition	Enrichment	CDKN2A	1.22
1176	Heritable thoracic aortic disease	Enrichment	SMAD4	1.22
1177	Immunodeficiency 109 with lymphoproliferation	Enrichment	TNFRSF9	1.22
1178	Congenital myopathy 26	Enrichment	TUBA4A	1.22
1179	Spastic ataxia 11, autosomal dominant	Enrichment	TUBA4A	1.22
1180	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	1.22
1181	Amyotrophic lateral sclerosis type 22	Enrichment	TUBA4A	1.22
1182	Lrp5-related primary osteoporosis	Enrichment	LRP5	1.22
1183	Pulmonary hypertension, primary, 7	Enrichment	SOX17	1.22
1184	Neurofibromatosis	Enrichment	NF1	1.22
1185	Oocyte/zygote/embryo maturation arrest 21	Enrichment	CHEK1	1.22
1186	Transient cerebral ischemia	Enrichment	NOTCH3	1.22
1187	Chromosome 17q11.2 deletion syndrome	Enrichment	NF1	1.22
1188	Primary pulmonary hypertension	Enrichment	BMPR2	1.22
1189	B-cell non-hodgkin lymphoma	Enrichment	ATM	1.22
1190	Optic nerve glioma	Enrichment	NF1	1.22
1191	Polymicrogyria with optic nerve hypoplasia	Enrichment	TUBA8	1.22
1192	Cerebral arteriopathy, autosomal recessive, with subcortical infarcts and leukoencephalopathy 1	Enrichment	NOTCH3	1.22
1193	Pulmonary hypertension	Enrichment	BMPR2	1.22
1194	Turner syndrome	Enrichment	PTCH1	1.22
1195	Familial adenomatous polyposis	Enrichment	APC	1.22
1196	Immunodeficiency 64	Enrichment	RASGRP1	1.22
1197	Gorham's disease	Enrichment	RASA1	1.22
1198	Chronic neutrophilic leukemia	Enrichment	CSF3R	1.22
1199	Ebv-induced lymphoproliferative disease due to rasgrp1 deficiency	Enrichment	RASGRP1	1.22
1200	Drug- or toxin-induced pulmonary arterial hypertension	Enrichment	BMPR2	1.22
1201	Common variable immunodeficiency phenotype due to homozygous taci deficiency	Enrichment	TNFRSF13B	1.22
1202	Autosomal recessive severe congenital neutropenia due to cxcr2 deficiency	Enrichment	CXCR2	1.22
1203	Menke-hennekam syndrome	Enrichment	CREBBP	1.22
1204	Monosomy 9q22.3	Enrichment	PTCH1	1.22
1205	Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome	Enrichment	ATR	1.22
1206	Gardner syndrome	Enrichment	APC	1.22
1207	Osteosclerosis-developmental delay-craniosynostosis syndrome	Enrichment	LRP5	1.22
1208	T-b+ severe combined immunodeficiency due to il-7ralpha deficiency	Enrichment	IL7R	1.22
1209	5q22 microdeletion syndrome	Enrichment	APC	1.22
1210	Pash syndrome	Enrichment	NCSTN	1.22
1211	Attenuated familial adenomatous polyposis	Enrichment	APC	1.22
1212	Huntington's disease-like	Enrichment	PSEN2	1.22
1213	Intestinal polyposis syndrome	Enrichment	STK11	1.22
1214	Mendelian susceptibility to mycobacterial diseases due to partial jak1 deficiency	Enrichment	JAK1	1.22
1215	Primary peritoneal carcinoma	Enrichment	BRCA1	1.22
1216	Polyvalvular heart disease syndrome	Enrichment	TAB2	1.22
1217	Retinal hemangioblastoma	Enrichment	VHL	1.22
1218	Lung oat cell carcinoma	Enrichment	RB1	1.22
1219	Myelodysplastic syndrome	Enrichment	GNB1, TP53	1.22
1220	Specific learning disability	Enrichment	MAPK1, RPS6KA3	1.22
1221	Esophageal cancer	Enrichment	TGFBR2, TP53	1.21
1222	Myelofibrosis	Enrichment	JAK2, SRC	1.21
1223	Adams-oliver syndrome	Enrichment	NOTCH1, RBPJ	1.21
1224	Early-onset autosomal dominant alzheimer disease	Enrichment	PSEN1, PSEN2	1.21
1225	Primary ovarian insufficiency	Enrichment	BMP6, CHEK2, JAK2, KDR, NBN, NOTCH2, NTRK1	1.21
1226	Hydrops fetalis, nonimmune	Enrichment	ACTA1, EPHB4, FLT4	1.20
1227	Cardiac conduction defect	Enrichment	DSP, FLNC	1.18
1228	Restrictive cardiomyopathy	Enrichment	FLNC, MYH7	1.18
1229	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	DSP, TGFB3	1.18
1230	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	DSP, TGFB3	1.18
1231	Postsynaptic congenital myasthenic syndromes	Enrichment	COL13A1, MUSK	1.18
1232	Eye disease	Enrichment	CACNA1F, CACNA2D4, GNAT2, IMPG2	1.16
1233	Cri-du-chat syndrome	Enrichment	SEMA5A	1.16
1234	Ehlers-danlos syndrome, vascular type	Enrichment	COL3A1	1.16
1235	Epiphyseal dysplasia, multiple, 1	Enrichment	COL1A1	1.16
1236	Tubulointerstitial kidney disease, autosomal dominant 1	Enrichment	HNF1B	1.16
1237	Amelogenesis imperfecta, type ib	Enrichment	COL17A1	1.16
1238	Aortic aneurysm, familial thoracic 4	Enrichment	MYH11	1.16
1239	Ectrodactyly and ectodermal dysplasia without cleft lip/palate	Enrichment	LEF1	1.16
1240	Leukocyte adhesion deficiency, type i	Enrichment	ITGB2	1.16
1241	Burkitt lymphoma	Enrichment	MYC	1.16
1242	Cutis laxa, autosomal dominant 1	Enrichment	ELN	1.16
1243	Ehlers-danlos syndrome, hypermobility type	Enrichment	COL3A1	1.16
1244	Blue rubber bleb nevus	Enrichment	TEK	1.16
1245	Renal cysts and diabetes syndrome	Enrichment	HNF1B	1.16
1246	Sveinsson chorioretinal atrophy	Enrichment	TEAD1	1.16
1247	Congenital anomalies of kidney and urinary tract 2	Enrichment	HNF1B	1.16
1248	Sorsby fundus dystrophy	Enrichment	TIMP3	1.16
1249	Mitral valve prolapse 1	Enrichment	DCHS1	1.16
1250	Wagner vitreoretinopathy	Enrichment	VCAN	1.16
1251	Maturity-onset diabetes of the young, type 1	Enrichment	HNF4A	1.16
1252	Myeloproliferative disorder, chronic, with eosinophilia	Enrichment	PDGFRB	1.16
1253	Metaphyseal chondrodysplasia, schmid type	Enrichment	COL10A1	1.16
1254	Camurati-engelmann disease 1	Enrichment	TGFB1	1.16
1255	Arthrogryposis, distal, type 2a	Enrichment	MYH3	1.16
1256	Insensitivity to pain, congenital, with anhidrosis	Enrichment	NTRK1	1.16
1257	Manitoba oculotrichoanal syndrome	Enrichment	FREM1	1.16
1258	Trichomegaly	Enrichment	FGF5	1.16
1259	Epidermolysis bullosa, junctional 2c, laryngoonychocutaneous	Enrichment	LAMA3	1.16
1260	Bruck syndrome 1	Enrichment	COL1A2	1.16
1261	Stiff skin syndrome	Enrichment	FBN1	1.16
1262	Camptodactyly-arthropathy-coxa vara-pericarditis syndrome	Enrichment	PRG4	1.16
1263	Kyphomelic dysplasia	Enrichment	CCN2	1.16
1264	Ebstein anomaly	Enrichment	MYH7	1.16
1265	Omodysplasia 1	Enrichment	GPC6	1.16
1266	Myasthenic syndrome, congenital, 5	Enrichment	LAMB2	1.16
1267	Otopalatodigital syndrome, type ii	Enrichment	FLNA	1.16
1268	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.16
1269	Van maldergem syndrome 1	Enrichment	DCHS1	1.16
1270	Melnick-needles syndrome	Enrichment	FLNA	1.16
1271	Pulmonary hypoplasia, primary	Enrichment	FGF10	1.16
1272	Arrhythmogenic right ventricular dysplasia, familial, 8	Enrichment	DSP	1.16
1273	Cataract 35	Enrichment	MYH9	1.16
1274	Hypotrichosis, congenital, with juvenile macular dystrophy	Enrichment	CDH3	1.16
1275	Frontometaphyseal dysplasia 1	Enrichment	FLNA	1.16
1276	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	1.16
1277	Deafness, autosomal dominant 30	Enrichment	MYO3A	1.16
1278	Bifid nose with or without anorectal and renal anomalies	Enrichment	FREM1	1.16
1279	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	1.16
1280	Parkinson disease 8, autosomal dominant	Enrichment	GDF6	1.16
1281	Aortic aneurysm, familial thoracic 2	Enrichment	ACTA2	1.16
1282	Doyne honeycomb retinal dystrophy	Enrichment	EFEMP1	1.16
1283	Griscelli syndrome, type 3	Enrichment	MYO5A	1.16
1284	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	1.16
1285	Aural atresia, congenital	Enrichment	FGFR2	1.16
1286	Legg-calve-perthes disease	Enrichment	COL2A1	1.16
1287	Arthrogryposis, distal, type 7	Enrichment	MYH8	1.16
1288	Deafness, autosomal dominant 20	Enrichment	ACTG1	1.16
1289	Keratosis, seborrheic	Enrichment	FGFR3	1.16
1290	Multiple synostoses syndrome 2	Enrichment	GDF5	1.16
1291	Smooth muscle dysfunction syndrome	Enrichment	ACTA2	1.16
1292	Leukocyte adhesion deficiency, type iii	Enrichment	ITGB2	1.16
1293	Lissencephaly 1	Enrichment	LAMB1	1.16
1294	Myopathy, mitochondrial progressive, with congenital cataract and developmental delay	Enrichment	GFER	1.16
1295	Cutis laxa, autosomal recessive, type ic	Enrichment	LTBP4	1.16
1296	Aortic aneurysm, familial thoracic 6	Enrichment	ACTA2	1.16
1297	Epithelial recurrent erosion dystrophy	Enrichment	COL17A1	1.16
1298	Baraitser-winter syndrome 2	Enrichment	ACTG1	1.16
1299	Specific language impairment 5	Enrichment	COL4A4	1.16
1300	Silver-russell syndrome 3	Enrichment	IGF2	1.16
1301	Osteogenesis imperfecta, type xiii	Enrichment	BMP1	1.16
1302	Beaulieu-boycott-innes syndrome	Enrichment	FBN1	1.16
1303	Moyamoya disease 5	Enrichment	ACTA2	1.16
1304	Deafness, autosomal recessive 84a	Enrichment	CDH23	1.16
1305	Pierson syndrome	Enrichment	LAMB2	1.16
1306	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	1.16
1307	Schwartz-jampel syndrome, type 1	Enrichment	HSPG2	1.16
1308	Keratosis palmoplantaris striata ii	Enrichment	DSP	1.16
1309	Brachydactyly, type a1, c	Enrichment	GDF5	1.16
1310	Symphalangism, proximal, 1b	Enrichment	GDF5	1.16
1311	Houge-janssens syndrome 1	Enrichment	PPP2R5D	1.16
1312	Supravalvular aortic stenosis	Enrichment	ELN	1.16
1313	Pain sensitivity quantitative trait locus 1	Enrichment	NTRK1	1.16
1314	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	1.16
1315	Spondyloepimetaphyseal dysplasia, li-shao-li type	Enrichment	CCN2	1.16
1316	Arthrogryposis, distal, type 2b3	Enrichment	MYH3	1.16
1317	Megacystis-microcolon-intestinal hypoperistalsis syndrome 2	Enrichment	MYH11	1.16
1318	Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy, 1	Enrichment	COL4A2	1.16
1319	Cardiomyopathy, dilated, with woolly hair, keratoderma, and tooth agenesis	Enrichment	DSP	1.16
1320	Combined osteogenesis imperfecta and ehlers-danlos syndrome 1	Enrichment	COL1A1	1.16
1321	Epidermolysis bullosa, junctional 3b, severe	Enrichment	LAMC2	1.16
1322	Epidermolysis bullosa, junctional 3a, intermediate	Enrichment	LAMC2	1.16
1323	Epidermolysis bullosa, junctional 4, intermediate	Enrichment	COL17A1	1.16
1324	Waardenburg syndrome, type 2f	Enrichment	KITLG	1.16
1325	Stickler syndrome, type vi	Enrichment	COL9A3	1.16
1326	Fibromuscular dysplasia, multifocal	Enrichment	COL5A1	1.16
1327	Lymphatic malformation 11	Enrichment	TIE1	1.16
1328	Epidermolysis bullosa, junctional 2a, intermediate	Enrichment	LAMA3	1.16
1329	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	ITGB4	1.16
1330	Cardiac valvular dysplasia, x-linked	Enrichment	FLNA	1.16
1331	Cebalid syndrome	Enrichment	MTOR	1.16
1332	Polymicrogyria with or without vascular-type ehlers-danlos syndrome	Enrichment	COL3A1	1.16
1333	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.16
1334	Kowarski syndrome	Enrichment	GH1	1.16
1335	Atrial septal defect 3	Enrichment	MYH6	1.16
1336	Nephrotic syndrome, type 5, with or without ocular abnormalities	Enrichment	LAMB2	1.16
1337	Hyperuricemic nephropathy, familial juvenile, 3	Enrichment	HNF1B	1.16
1338	Immunodeficiency 127	Enrichment	TNF	1.16
1339	Combined saposin deficiency	Enrichment	CDH23	1.16
1340	Recessive dystrophic epidermolysis bullosa	Enrichment	COL7A1	1.16
1341	Marfanoid-progeroid-lipodystrophy syndrome	Enrichment	FBN1	1.16
1342	Senior-loken syndrome 7	Enrichment	AKT3	1.16
1343	Progressive familial heart block	Enrichment	DSP	1.16
1344	Rosette-forming glioneuronal tumor	Enrichment	FGFR1	1.16
1345	Cataract 30	Enrichment	VIM	1.16
1346	Cardiovascular system disease	Enrichment	FLNC	1.16
1347	Cardiomyopathy, familial hypertrophic, 10	Enrichment	MYL2	1.16
1348	Optic disk drusen	Enrichment	EFEMP1	1.16
1349	Papillary renal cell carcinoma	Enrichment	MET	1.16
1350	Congenital mesoblastic nephroma	Enrichment	NTRK3	1.16
1351	Camurati-engelmann disease	Enrichment	TGFB1	1.16
1352	Glomerulonephritis	Enrichment	COL4A4	1.16
1353	Cardiomyopathy, dilated, with woolly hair and keratoderma	Enrichment	DSP	1.16
1354	Microphthalmia/coloboma 6	Enrichment	GDF6	1.16
1355	Glaucoma, primary closed-angle	Enrichment	COL18A1	1.16
1356	Trigonocephaly 2	Enrichment	FREM1	1.16
1357	Steel syndrome	Enrichment	COL27A1	1.16
1358	Familial avascular necrosis of the femoral head	Enrichment	COL2A1	1.16
1359	Hereditary inclusion body myopathy-joint contractures-ophthalmoplegia syndrome	Enrichment	MYH2	1.16
1360	Pseudosarcomatous fibromatosis	Enrichment	MYH9	1.16
1361	Immune system disease	Enrichment	CDC42	1.16
1362	Fibrosarcoma	Enrichment	NTRK3	1.16
1363	Visceral myopathy 2	Enrichment	MYH11	1.16
1364	Myopathy, myofibrillar, 12, infantile-onset, with cardiomyopathy	Enrichment	MYL2	1.16
1365	Bardet-biedl syndrome 16	Enrichment	AKT3	1.16
1366	Epidermolysis bullosa, junctional 2b, severe	Enrichment	LAMA3	1.16
1367	Cataract 16, multiple types	Enrichment	COL12A1	1.16
1368	Retinitis pigmentosa 38	Enrichment	MERTK	1.16
1369	Proximal symphalangism	Enrichment	GDF5	1.16
1370	Klippel-feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism	Enrichment	MYO18B	1.16
1371	Smith-kingsmore syndrome	Enrichment	MTOR	1.16
1372	Craniosynostosis 7	Enrichment	BMP2	1.16
1373	Combined psap deficiency	Enrichment	CDH23	1.16
1374	Acute myeloid leukemia without maturation	Enrichment	FLT3	1.16
1375	Congenital amegakaryocytic thrombocytopenia	Enrichment	THPO	1.16
1376	Mitochondrial dna depletion syndrome 15	Enrichment	TFAM	1.16
1377	Arthrogryposis, distal, type 1c	Enrichment	MYL11	1.16
1378	Megacystis-microcolon-intestinal hypoperistalsis syndrome 4	Enrichment	MYL9	1.16
1379	Houge-janssens syndrome 3	Enrichment	PPP2CA	1.16
1380	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.16
1381	Intermittent hydrarthrosis	Enrichment	TNFRSF1A	1.16
1382	Klippel-feil anomaly-myopathy-facial dysmorphism syndrome	Enrichment	MYO18B	1.16
1383	Short stature due to growth hormone qualitative anomaly	Enrichment	GH1	1.16
1384	Wagner disease	Enrichment	VCAN	1.16
1385	B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3)	Enrichment	TCF3	1.16
1386	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	1.16
1387	Chronic eosinophilic leukemia	Enrichment	PDGFRA	1.16
1388	Vacterl with hydrocephalus	Enrichment	PTEN	1.16
1389	Growth delay due to insulin-like growth factor type 1 deficiency	Enrichment	IGF1	1.16
1390	Hyperinsulinism	Enrichment	HNF4A	1.16
1391	Dentinogenesis imperfecta	Enrichment	COL1A2	1.16
1392	Childhood-onset autosomal recessive myopathy with external ophthalmoplegia	Enrichment	MYH2	1.16
1393	Epidermolysis bullosa dystrophica	Enrichment	COL7A1	1.16
1394	Teratoma	Enrichment	CTNNB1	1.16
1395	B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality	Enrichment	PDGFRA	1.16
1396	Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2)	Enrichment	FLT3	1.16
1397	B-lymphoblastic leukemia/lymphoma with t	Enrichment	KIT	1.16
1398	B-lymphoblastic leukemia/lymphoma with t(17;19)	Enrichment	TCF3	1.16
1399	Common variable immunodeficiency 12	Enrichment	NFKB1	1.16
1400	Lens subluxation	Enrichment	FBN1	1.16
1401	Familial isolated pituitary adenoma	Enrichment	CDH23	1.16
1402	Silver-russell syndrome due to an imprinting defect of 11p15	Enrichment	IGF2	1.16
1403	Intestinal obstruction	Enrichment	ACTG2	1.16
1404	Silver-russell syndrome due to 11p15 microduplication	Enrichment	IGF2	1.16
1405	Carney complex - trismus - pseudocamptodactyly syndrome	Enrichment	MYH8	1.16
1406	Fibromatosis, gingival, 1	Enrichment	SOS1	1.14
1407	Pseudohypoparathyroidism, type ia	Enrichment	GNAS	1.14
1408	Scoliosis, isolated 1	Enrichment	MAPK7	1.14
1409	Adrenocortical carcinoma, hereditary	Enrichment	TP53	1.14
1410	Costello syndrome	Enrichment	HRAS	1.14
1411	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	1.14
1412	Pituitary adenoma 4, acth-secreting	Enrichment	GNAI2	1.14
1413	Hemangiopericytoma, malignant	Enrichment	STAT6	1.14
1414	Cutis marmorata telangiectatica congenita	Enrichment	GNA11	1.14
1415	Growth hormone insensitivity syndrome with immune dysregulation 1, autosomal recessive	Enrichment	STAT5B	1.14
1416	Immunodeficiency 33	Enrichment	IRAK4	1.14
1417	Immunodeficiency 41 with lymphoproliferation and autoimmunity	Enrichment	IL2RA	1.14
1418	Pseudopseudohypoparathyroidism	Enrichment	GNAS	1.14
1419	Lethal congenital contracture syndrome 8	Enrichment	ADCY6	1.14
1420	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.14
1421	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.14
1422	Spermatogenic failure 17	Enrichment	PLCZ1	1.14
1423	Lymphoma, hodgkin, classic	Enrichment	TP53	1.14
1424	Immunodeficiency 31c	Enrichment	STAT1	1.14
1425	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	1.14
1426	Neurodevelopmental disorder with or without variable brain abnormalities	Enrichment	MAPK8IP3	1.14
1427	Noonan syndrome 12	Enrichment	RRAS2	1.14
1428	Usher syndrome, type iv	Enrichment	PRKAR1A	1.14
1429	Intravascular large b-cell lymphoma	Enrichment	BCL2	1.14
1430	Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome	Enrichment	ITGA3	1.14
1431	Autosomal dominant hypocalcemia	Enrichment	GNA11	1.14
1432	Acrodysostosis	Enrichment	PRKAR1A	1.14
1433	Pseudohypoparathyroidism	Enrichment	GNAS	1.14
1434	Body mass index quantitative trait locus 19	Enrichment	ADCY3	1.14
1435	Congenital dyserythropoietic anemia	Enrichment	IRAK4	1.14
1436	Fibrolamellar carcinoma	Enrichment	PRKACA	1.14
1437	Ocular melanoma	Enrichment	PLCB4	1.14
1438	Hodgkin's lymphoma	Enrichment	TP53	1.14
1439	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	1.14
1440	Hypopituitarism	Enrichment	GNAI2	1.14
1441	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.14
1442	Immunodeficiency 57 with autoinflammation	Enrichment	RIPK1	1.14
1443	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PRKAR1A	1.14
1444	Acth-independent macronodular adrenal hyperplasia	Enrichment	GNAS	1.14
1445	Transient predisposition to invasive pyogenic bacterial infection	Enrichment	IRAK4	1.14
1446	Tafro syndrome	Enrichment	MAP2K2	1.14
1447	Laron syndrome with immunodeficiency	Enrichment	STAT5B	1.14
1448	Cerebral visual impairment	Enrichment	GNB1	1.14
1449	Phakomatosis cesioflammea	Enrichment	GNA11	1.14
1450	Wooly hair nevus	Enrichment	HRAS	1.14
1451	Chronic kidney disease	Enrichment	COL4A4, COL4A5	1.12
1452	Amyotrophy, hereditary neuralgic	Enrichment	SEPTIN9	1.10
1453	Alexander disease	Enrichment	GFAP	1.10
1454	Wiskott-aldrich syndrome	Enrichment	WIPF1	1.10
1455	Lethal congenital contracture syndrome 3	Enrichment	PIP5K1C	1.10
1456	Isolated growth hormone deficiency, type iii, with agammaglobulinemia	Enrichment	BTK	1.10
1457	Neutrophilia, hereditary	Enrichment	PIP4K2B	1.10
1458	Cardiomyopathy, dilated, 1i	Enrichment	DES	1.10
1459	Osteopetrosis, autosomal recessive 2	Enrichment	TNFSF11	1.10
1460	Neutropenia, severe congenital, 7, autosomal recessive	Enrichment	PIP4K2B	1.10
1461	Spastic paraplegia, intellectual disability, nystagmus, and obesity	Enrichment	GFAP	1.10
1462	Genitourinary and/or brain malformation syndrome	Enrichment	PPP1R12A	1.10
1463	Agammaglobulinemia, x-linked	Enrichment	BTK	1.10
1464	Severe congenital neutropenia 7	Enrichment	PIP4K2B	1.10
1465	Intellectual developmental disorder, autosomal dominant 60, with seizures	Enrichment	PIP5K1A	1.10
1466	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	PIP4K2A	1.10
1467	Lymphatic malformation 10	Enrichment	ANGPT2	1.10
1468	Chromosome 1p36 deletion syndrome	Enrichment	HSPG2, PRKCZ	1.09
1469	Keratitis, hereditary	Enrichment	PAX6	1.06
1470	Foveal hypoplasia 1	Enrichment	PAX6	1.06
1471	Timothy syndrome	Enrichment	CACNA1C	1.06
1472	Night blindness, congenital stationary, type 2a	Enrichment	CACNA1F	1.06
1473	Alternating hemiplegia of childhood 1	Enrichment	CACNA1A	1.06
1474	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	1.06
1475	Optic nerve hypoplasia, bilateral	Enrichment	PAX6	1.06
1476	Spastic paraplegia 76, autosomal recessive	Enrichment	CAPN1	1.06
1477	Long qt syndrome 8	Enrichment	CACNA1C	1.06
1478	Ectodermal dysplasia and immune deficiency	Enrichment	NFKBIA	1.06
1479	Immunodeficiency 17	Enrichment	CD3G	1.06
1480	Congenital disorder of glycosylation, type iw, autosomal dominant	Enrichment	CACNA1D	1.06
1481	Immunodeficiency 52	Enrichment	LAT	1.06
1482	Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements	Enrichment	CACNA1B	1.06
1483	Progressive bulbar palsy	Enrichment	CACNA1A	1.06
1484	Hereditary retinal dystrophy	Enrichment	ATF6, CDH23, CDH3, COL11A2, COL18A1, COL2A1, COL9A1, EFEMP1, IMPG1, IMPG2, LAMA1, MERTK, MYO7A, TIMP3, VCAN	1.03
1485	Fundus dystrophy	Enrichment	ATF6, CDH23, CDH3, COL11A2, COL18A1, COL2A1, COL9A1, EFEMP1, IMPG1, IMPG2, LAMA1, MERTK, MYO7A, TIMP3, VCAN	1.03
1486	Severe covid-19	Enrichment	CASP10, IL10RB, ITGAV, JAK3	1.03
1487	Neural tube defects	Enrichment	ITGB1, PARD3	1.03
1488	Corpus callosum, agenesis of	Enrichment	CDH2, COL4A1	1.01
1489	Usher syndrome, type i	Enrichment	CDH23, MYO7A	1.01
1490	Isolated corpus callosum agenesis	Enrichment	CDH2, COL4A1	1.01
1491	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CDH2, COL4A1	1.01
1492	Charge syndrome	Enrichment	EP300, TNFRSF1A	1.01
1493	Leukemia, acute lymphoblastic 3	Enrichment	JAK2, NF1	1.01
1494	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	CSF3R, FLT3	1.01
1495	Hypogonadotropic hypogonadism	Enrichment	FGFR1, SOX11	1.01
1496	Primary biliary cholangitis	Enrichment	IL12A, IL12RB1	1.01
1497	Prune belly syndrome	Enrichment	FLNA	0.99
1498	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	Enrichment	MYH9	0.99
1499	Retinal arteries, tortuosity of	Enrichment	COL4A1	0.99
1500	Hypogonadotropic hypogonadism 2 with or without anosmia	Enrichment	FGFR1	0.99
1501	Palmoplantar keratoderma, punctate type ia	Enrichment	COL14A1	0.99
1502	Spondyloepiphyseal dysplasia congenita	Enrichment	COL2A1	0.99
1503	Exfoliation syndrome	Enrichment	LTBP2	0.99
1504	Arterial tortuosity syndrome	Enrichment	FLNA	0.99
1505	Tumoral calcinosis, hyperphosphatemic, familial, 1	Enrichment	FGF23	0.99
1506	Thrombocythemia 1	Enrichment	THPO	0.99
1507	Hypophosphatemic rickets, autosomal dominant	Enrichment	FGF23	0.99
1508	Megalocornea	Enrichment	COL11A1	0.99
1509	Dyssegmental dysplasia, silverman-handmaker type	Enrichment	HSPG2	0.99
1510	Nail disorder, nonsyndromic congenital, 4	Enrichment	COL7A1	0.99
1511	Hypophosphatasia, infantile	Enrichment	COL11A2	0.99
1512	Periventricular nodular heterotopia 1	Enrichment	FLNA	0.99
1513	Leukoencephalopathy, hereditary diffuse, with spheroids 1	Enrichment	CSF1R	0.99
1514	Mullerian duct aplasia, unilateral renal agenesis, and cervicothoracic somite anomalies	Enrichment	HNF1B	0.99
1515	Deafness, autosomal recessive 3	Enrichment	MYO15A	0.99
1516	Stuve-wiedemann syndrome 1	Enrichment	LIFR	0.99
1517	Myopathy, myofibrillar, 5	Enrichment	FLNC	0.99
1518	Cardiomyopathy, dilated, 1c, with or without left ventricular noncompaction	Enrichment	MYH7B	0.99
1519	Glomerulopathy with fibronectin deposits 2	Enrichment	FN1	0.99
1520	Muscular dystrophy, duchenne type	Enrichment	LTBP4	0.99
1521	Transposition of the great arteries, dextro-looped	Enrichment	BMP2	0.99
1522	Corneal dystrophy, posterior polymorphous, 3	Enrichment	ZEB1	0.99
1523	Corneal dystrophy, fuchs endothelial, 6	Enrichment	ZEB1	0.99
1524	Muscular dystrophy, congenital merosin-deficient, 1a	Enrichment	LAMA2	0.99
1525	Epidermolysis bullosa, lethal acantholytic	Enrichment	DSP	0.99
1526	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	0.99
1527	Congenital short bowel syndrome	Enrichment	FLNA	0.99
1528	Caffey disease	Enrichment	COL1A1	0.99
1529	Brain small vessel disease 2	Enrichment	COL4A2	0.99
1530	Chromosome 8p11 myeloproliferative syndrome	Enrichment	FGFR1	0.99
1531	Ullrich congenital muscular dystrophy 2	Enrichment	COL12A1	0.99
1532	Bethlem myopathy 2	Enrichment	COL12A1	0.99
1533	Dyskeratosis congenita, autosomal dominant 6	Enrichment	THPO	0.99
1534	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	0.99
1535	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	0.99
1536	Chromosome 17q12 deletion syndrome	Enrichment	HNF1B	0.99
1537	Myopathy, distal, 4	Enrichment	FLNC	0.99
1538	Anus, imperforate	Enrichment	CTNNB1	0.99
1539	Microangiopathy and leukoencephalopathy, pontine, autosomal dominant	Enrichment	COL4A1	0.99
1540	Erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis, and hyper-ige	Enrichment	DSP	0.99
1541	Microcephaly, progressive, with seizures and cerebral and cerebellar atrophy	Enrichment	MYH15	0.99
1542	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	0.99
1543	Keratoderma-ichthyosis-deafness syndrome, autosomal recessive	Enrichment	HNF1A	0.99
1544	Pilarowski-bjornsson syndrome	Enrichment	COL4A3	0.99
1545	Woolly hair-skin fragility syndrome	Enrichment	DSP	0.99
1546	Alport syndrome 3b, autosomal recessive	Enrichment	COL4A3	0.99
1547	Bronchopulmonary dysplasia	Enrichment	MUSK	0.99
1548	Cutis laxa, autosomal recessive, type ib	Enrichment	EFEMP2	0.99
1549	Poretti-boltshauser syndrome	Enrichment	LAMA1	0.99
1550	Keratosis palmoplantaris striata	Enrichment	DSP	0.99
1551	Isolated ectopia lentis	Enrichment	FBN1	0.99
1552	Intrinsic cardiomyopathy	Enrichment	ACTN2	0.99
1553	Autosomal dominant cutis laxa	Enrichment	ELN	0.99
1554	Isolated growth hormone deficiency, type ib	Enrichment	GH1	0.99
1555	Angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps	Enrichment	COL4A1	0.99
1556	Lymphatic malformation 7	Enrichment	EPHB4	0.99
1557	Frontometaphyseal dysplasia	Enrichment	FLNA	0.99
1558	Immunodeficiency 14	Enrichment	PIK3R1	0.99
1559	Capillary malformation-arteriovenous malformation 2	Enrichment	EPHB4	0.99
1560	Intraocular pressure quantitative trait locus	Enrichment	ZEB1	0.99
1561	Hematuria, benign familial, 2	Enrichment	COL4A3	0.99
1562	Cryptogenic cirrhosis	Enrichment	KRT18	0.99
1563	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	0.99
1564	Qualitative or quantitative defects of beta-myosin heavy chain	Enrichment	MYH7	0.99
1565	Idiopathic camptocormia	Enrichment	MYH7	0.99
1566	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	0.99
1567	Congenital diarrhea	Enrichment	MYO1A	0.99
1568	Tricuspid valve insufficiency	Enrichment	MYH11	0.99
1569	Mixed phenotype acute leukemia with t	Enrichment	FLT3	0.99
1570	Alopecia - intellectual disability syndrome	Enrichment	ITGB6	0.99
1571	Renal cell carcinoma	Enrichment	MET	0.99
1572	Enchondromatosis	Enrichment	HIF1A	0.99
1573	Multiple epiphyseal dysplasia	Enrichment	COL2A1	0.99
1574	Stüve-wiedemann syndrome	Enrichment	LIFR	0.99
1575	Isolated klippel-feil syndrome	Enrichment	GDF6	0.99
1576	Beckwith-wiedemann syndrome due to imprinting defect of 11p15	Enrichment	IGF2	0.99
1577	Familial drusen	Enrichment	EFEMP1	0.99
1578	Hyperpigmentation of the skin	Enrichment	COL7A1	0.99
1579	Lama2-related muscular dystrophy	Enrichment	LAMA2	0.99
1580	Undetermined early-onset epileptic encephalopathy	Enrichment	CACNA1A, CACNA1B, CACNA2D1, FGF12, NTRK2	0.98
1581	Nuchal bleb, familial	Enrichment	SOS1	0.97
1582	Nephrotic syndrome, type 3	Enrichment	PLCE1	0.97
1583	Muscular dystrophy, congenital, due to integrin alpha-7 deficiency	Enrichment	ITGA7	0.97
1584	Epidermolysis bullosa, junctional 6, with pyloric atresia	Enrichment	ITGA6	0.97
1585	Hyper ige syndrome	Enrichment	STAT3	0.97
1586	Atypical teratoid rhabdoid tumor	Enrichment	TP53	0.97
1587	Anaplastic astrocytoma	Enrichment	TP53	0.97
1588	Myxoid liposarcoma	Enrichment	DDIT3	0.97
1589	Immunodeficiency 44	Enrichment	STAT2	0.97
1590	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	GNAS	0.97
1591	Hypomyelination neuropathy-arthrogryposis syndrome	Enrichment	ADCY6	0.97
1592	Autism spectrum disorder	Enrichment	GNB1, MAP2K1, MEF2C, SMC3, TCF12, TCF20, TCF4	0.95
1593	Macs syndrome	Enrichment	GDF6, PTCH1, SOX2	0.94
1594	Takayasu arteritis	Enrichment	IL12B	0.94
1595	Immunodeficiency 98 with autoinflammation, x-linked	Enrichment	FASLG	0.94
1596	Granulomatous disease, chronic, autosomal recessive, 2	Enrichment	NCF2	0.94
1597	Myopathy, myofibrillar, 1	Enrichment	DES	0.94
1598	Agammaglobulinemia 1, autosomal recessive	Enrichment	BTK	0.94
1599	Aortic aneurysm, familial thoracic 7	Enrichment	MYLK	0.94
1600	Agammaglobulinemia 1	Enrichment	BTK	0.94
1601	Microcephaly 17, primary, autosomal recessive	Enrichment	CIT	0.94
1602	Immunodeficiency, common variable, 11	Enrichment	IL21	0.94
1603	Cafe-au-lait spots, multiple	Enrichment	NF1	0.93
1604	Melanoma-astrocytoma syndrome	Enrichment	CDKN2A	0.93
1605	Peutz-jeghers syndrome	Enrichment	STK11	0.93
1606	Familial expansile osteolysis	Enrichment	TNFRSF11A	0.93
1607	Myhre syndrome	Enrichment	SMAD4	0.93
1608	Campomelic dysplasia	Enrichment	SOX9	0.93
1609	Van buchem disease	Enrichment	LRP5	0.93
1610	Pallister-hall-like syndrome	Enrichment	SMO	0.93
1611	Paget disease of bone 5, juvenile-onset	Enrichment	TNFRSF11A	0.93
1612	Immunodeficiency, common variable, 2	Enrichment	TNFRSF13B	0.93
1613	Thumb deformity	Enrichment	CREBBP	0.93
1614	Pulmonary venoocclusive disease 1, autosomal dominant	Enrichment	BMPR2	0.93
1615	Ovarian germ cell cancer	Enrichment	CBL	0.93
1616	Alzheimer disease 3	Enrichment	PSEN1	0.93
1617	West nile virus	Enrichment	CCR5	0.93
1618	Hypertrichosis, congenital generalized, 2	Enrichment	SOX3	0.93
1619	46,xy gonadal dysgenesis with minifascicular neuropathy	Enrichment	DHH	0.93
1620	Inflammatory bowel disease 28, autosomal recessive	Enrichment	IL10RA	0.93
1621	Waardenburg syndrome, type 4c	Enrichment	SOX10	0.93
1622	Pick disease of brain	Enrichment	PSEN1	0.93
1623	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	0.93
1624	Immunodeficiency with hyper-igm, type 2	Enrichment	TNFRSF13B	0.93
1625	Microvascular complications of diabetes 5	Enrichment	TGFBR2	0.93
1626	Intellectual developmental disorder, autosomal recessive 5	Enrichment	SYNGAP1	0.93
1627	Osteogenesis imperfecta, type xv	Enrichment	WNT1	0.93
1628	Melanoma, cutaneous malignant 2	Enrichment	CDKN2A	0.93
1629	Adams-oliver syndrome 5	Enrichment	NOTCH1	0.93
1630	Robinow syndrome, autosomal dominant 3	Enrichment	FZD2	0.93
1631	Chromosome 13q14 deletion syndrome	Enrichment	RB1	0.93
1632	Thrombocythemia 3	Enrichment	JAK2	0.93
1633	Immunodeficiency 51	Enrichment	IL17RA	0.93
1634	Heterotaxy, visceral, 4, autosomal	Enrichment	ACVR2B	0.93
1635	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	0.93
1636	Deafness, autosomal dominant 64	Enrichment	DIABLO	0.93
1637	Loeys-dietz syndrome 3	Enrichment	SMAD3	0.93
1638	Adams-oliver syndrome 3	Enrichment	RBPJ	0.93
1639	Congenital heart defects, multiple types, 3	Enrichment	CHEK2	0.93
1640	Cortical dysplasia, complex, with other brain malformations 4	Enrichment	TUBG1	0.93
1641	Blepharocheilodontic syndrome 2	Enrichment	CTNND1	0.93
1642	Congenital heart defects and skeletal malformations syndrome	Enrichment	ABL1	0.93
1643	Fanconi anemia, complementation group s	Enrichment	BRCA1	0.93
1644	Menke-hennekam syndrome 2	Enrichment	EP300	0.93
1645	Chromosome 17q11.2 duplication syndrome, 1.4-mb	Enrichment	NF1	0.93
1646	Pulmonary venoocclusive disease 1	Enrichment	BMPR2	0.93
1647	Pancreatic cancer 4	Enrichment	BRCA1	0.93
1648	Primary cutaneous amyloidosis	Enrichment	OSMR	0.93
1649	Immunodeficiency, common variable, 4	Enrichment	TNFRSF13C	0.93
1650	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	0.93
1651	Melanoma-pancreatic cancer syndrome	Enrichment	CDKN2A	0.93
1652	Lipodystrophy, familial partial, type 1	Enrichment	NOTCH3	0.93
1653	Depressive disorder	Enrichment	NOTCH3	0.93
1654	High grade glioma	Enrichment	ATM	0.93
1655	Inflammatory bowel disease 28	Enrichment	IL10RA	0.93
1656	Immunodeficiency 104, severe combined	Enrichment	IL7R	0.93
1657	Peripheral demyelinating neuropathy, central dysmyelination, waardenburg syndrome, and hirschsprung disease	Enrichment	SOX10	0.93
1658	Inflammatory skin and bowel disease, neonatal, 1	Enrichment	ADAM17	0.93
1659	Autoinflammation, immune dysregulation, and eosinophilia	Enrichment	JAK1	0.93
1660	Multiple sclerosis 3	Enrichment	IL7R	0.93
1661	Cortical dysplasia, complex, with other brain malformations 1	Enrichment	TUBB3	0.93
1662	Congenital heart defects, multiple types, 2	Enrichment	TAB2	0.93
1663	Bardet-biedl syndrome 9	Enrichment	NF1	0.93
1664	Periampullary adenoma	Enrichment	APC	0.93
1665	Gastric adenocarcinoma and proximal polyposis of the stomach	Enrichment	APC	0.93
1666	T-cell prolymphocytic leukemia	Enrichment	ATM	0.93
1667	Inflammatory breast carcinoma	Enrichment	BRCA1	0.93
1668	Polycythemia	Enrichment	JAK2	0.93
1669	Hereditary mixed polyposis syndrome	Enrichment	BMPR1A	0.93
1670	Peritoneum cancer	Enrichment	BRCA1	0.93
1671	Basal cell nevus syndrome 2	Enrichment	SUFU	0.93
1672	Bilateral breast cancer	Enrichment	BRCA1	0.93
1673	Postaxial polydactyly type b	Enrichment	GLI1	0.93
1674	Hypereosinophilic syndrome	Enrichment	JAK2	0.93
1675	Acute leukemia of ambiguous lineage	Enrichment	VHL	0.93
1676	Malignant germ cell tumor of ovary	Enrichment	CBL	0.93
1677	Cardiac anomalies-short stature-joint hypermobility-facial dysmorphism syndrome	Enrichment	TAB2	0.93
1678	Pulmonary venoocclusive disease	Enrichment	BMPR2	0.93
1679	Osteosclerosis	Enrichment	LRP5	0.93
1680	Familial retinoblastoma	Enrichment	RB1	0.93
1681	Commissural facial cleft	Enrichment	PTCH2	0.93
1682	Oculootodental syndrome	Enrichment	FADD	0.93
1683	Idiopathic/heritable pulmonary arterial hypertension	Enrichment	BMPR2	0.93
1684	Campomelic dysplasia and related disorders	Enrichment	SOX9	0.93
1685	Lynch syndrome 1	Enrichment	ATM, CHEK2	0.93
1686	Omenn syndrome	Enrichment	IL2RG, IL7R	0.93
1687	Cleft palate, isolated	Enrichment	COL11A1, FLNA	0.92
1688	Cardiomyopathy, dilated, 1e	Enrichment	MYH7, MYL2	0.92
1689	Jacobsen syndrome	Enrichment	ETS1	0.89
1690	Type 1 diabetes mellitus 2	Enrichment	CAPN10	0.89
1691	Van der woude syndrome 1	Enrichment	CACNA1E	0.89
1692	Gillespie syndrome	Enrichment	PAX6	0.89
1693	Estrogen resistance	Enrichment	ESR1	0.89
1694	Muscular dystrophy, limb-girdle, autosomal dominant 4	Enrichment	CAPN3	0.89
1695	Autosomal recessive limb-girdle muscular dystrophy type 2a	Enrichment	CAPN3	0.89
1696	Neurodegeneration, childhood-onset, with brain atrophy	Enrichment	UBTF	0.89
1697	Thyrotoxic periodic paralysis	Enrichment	CACNA1S	0.89
1698	Hereditary episodic ataxia	Enrichment	CACNA1A	0.89
1699	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	MAX, NF1, VHL	0.89
1700	Dandy-walker syndrome	Enrichment	BRAF, PDGFRB	0.89
1701	Neuromuscular disease	Enrichment	ACTA1, MYH7	0.88
1702	Kaposi sarcoma	Enrichment	IL6	0.87
1703	Myopathy, distal, 1	Enrichment	MYH7	0.87
1704	Retinitis pigmentosa 91	Enrichment	IMPG1	0.87
1705	Amelogenesis imperfecta, type iiia	Enrichment	ITGB6	0.87
1706	Isolated growth hormone deficiency, type ii	Enrichment	GH1	0.87
1707	Klippel-feil syndrome 2, autosomal recessive	Enrichment	MYO18B	0.87
1708	Nemaline myopathy 2	Enrichment	ACTA1	0.87
1709	Phenylketonuria	Enrichment	COL1A1	0.87
1710	Congenital myopathy 7b, myosin storage, autosomal recessive	Enrichment	MYH7	0.87
1711	Schizencephaly	Enrichment	COL4A1	0.87
1712	Microtia-anotia	Enrichment	BMP5	0.87
1713	Pitt-hopkins syndrome	Enrichment	TCF4	0.87
1714	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	0.87
1715	Epidermolysis bullosa simplex 5c, with pyloric atresia	Enrichment	ITGB4	0.87
1716	Pilomatrixoma	Enrichment	CTNNB1	0.87
1717	Carney complex variant	Enrichment	MYH8	0.87
1718	Congenital myopathy 7a, myosin storage, autosomal dominant	Enrichment	MYH7	0.87
1719	Congenital myopathy 6 with ophthalmoplegia	Enrichment	MYH2	0.87
1720	Barrett esophagus	Enrichment	ERBB2	0.87
1721	Aminoacylase 1 deficiency	Enrichment	ACTB	0.87
1722	Pituitary adenoma 5, multiple types	Enrichment	CDH23	0.87
1723	Cardiomyopathy, familial hypertrophic, 26	Enrichment	FLNC	0.87
1724	Arthrogryposis multiplex congenita 2, neurogenic type	Enrichment	COL25A1	0.87
1725	Alazami syndrome	Enrichment	CTNNB1	0.87
1726	Congenital generalized lipodystrophy	Enrichment	FOS	0.87
1727	Contractures, pterygia, and spondylocarpotarsal fusion syndrome 1b	Enrichment	MYH3	0.87
1728	Hyaline body myopathy	Enrichment	MYH7	0.87
1729	Chronic myelomonocytic leukemia	Enrichment	FLT3	0.87
1730	Prolactinoma	Enrichment	CDH23	0.87
1731	Epidermolytic hyperkeratosis	Enrichment	COL7A1	0.87
1732	Cerebral malaria	Enrichment	TNF	0.87
1733	Vacterl association	Enrichment	CDH13	0.87
1734	Silver-russell syndrome due to a point mutation	Enrichment	IGF2	0.87
1735	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	KIT	0.87
1736	Intermediate nemaline myopathy	Enrichment	ACTA1	0.87
1737	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	0.87
1738	Rare x-linked non-syndromic sensorineural deafness type dfn	Enrichment	COL4A6	0.87
1739	Clear cell papillary renal cell carcinoma	Enrichment	HNF1A	0.87
1740	Familial sick sinus syndrome	Enrichment	MYH6	0.87
1741	Immune deficiency disease	Enrichment	ATM, CD27	0.86
1742	Frontotemporal dementia 1	Enrichment	CSF1R, PSEN1	0.86
1743	Combined immunodeficiency	Enrichment	CD27, IL2RG	0.86
1744	46,xy complete gonadal dysgenesis	Enrichment	DHH, SOX9	0.86
1745	Ichthyosis	Enrichment	COL7A1, IL2RB	0.86
1746	Combined t cell and b cell immunodeficiency	Enrichment	CD27, IL2RG	0.86
1747	Combined t and b cell immunodeficiency	Enrichment	CD27, IL2RG	0.86
1748	Chorea, benign hereditary	Enrichment	ADCY5	0.85
1749	Neuropathy, hereditary sensory and autonomic, type iia	Enrichment	WNK1	0.85
1750	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	0.85
1751	Pseudohypoparathyroidism, type ib	Enrichment	GNAS	0.85
1752	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	0.85
1753	Retinitis pigmentosa 26	Enrichment	ITGA4	0.85
1754	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	0.85
1755	Developmental and epileptic encephalopathy 12	Enrichment	PLCB1	0.85
1756	Hereditary sensory and autonomic neuropathy type 2	Enrichment	WNK1	0.85
1757	Hereditary ataxia	Enrichment	PRKCG	0.85
1758	Newborn respiratory distress syndrome	Enrichment	BRAF	0.85
1759	Epidermolytic nevus	Enrichment	HRAS	0.85
1760	Gingival fibromatosis	Enrichment	SOS1	0.85
1761	Microphthalmia	Enrichment	PTCH1, RARB, SOX2	0.85
1762	Tooth agenesis	Enrichment	FGFR1, LRP6, TGFA	0.85
1763	Anterior segment dysgenesis	Enrichment	COL4A1, PAX6	0.84
1764	Congenital myopathy	Enrichment	ACTA1, MYH7	0.84
1765	Autosomal recessive osteopetrosis	Enrichment	TNFSF11	0.82
1766	Inherited epidermodysplasia verruciformis	Enrichment	IL7	0.82
1767	Hereditary angioedema with normal c1inh not related to f12 or plg variant	Enrichment	ANGPT1	0.82
1768	Fanconi anemia, complementation group a	Enrichment	BRCA1, FANCD2, RAD51, VHL	0.81
1769	Creatine phosphokinase, elevated serum	Enrichment	CAPN3, LAMA2	0.80
1770	Isolated elevated serum creatine phosphokinase levels	Enrichment	CAPN3, LAMA2	0.80
1771	Epicanthus	Enrichment	ACVR1, TCF4	0.80
1772	Cataract 6, multiple types	Enrichment	EPHA2	0.78
1773	Enchondromatosis, multiple, ollier type	Enrichment	HIF1A	0.78
1774	Polycystic liver disease 1 with or without kidney cysts	Enrichment	FBN1	0.78
1775	Epidermolytic hyperkeratosis 1	Enrichment	COL7A1	0.78
1776	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	0.78
1777	Epidermolysis bullosa simplex 1c, localized	Enrichment	ITGB4	0.78
1778	Arthrogryposis, renal dysfunction, and cholestasis 1	Enrichment	FBN1	0.78
1779	Vater/vacterl association	Enrichment	CDH13	0.78
1780	Arthrogryposis, distal, type 2b1	Enrichment	MYH3	0.78
1781	Deafness, autosomal recessive 9	Enrichment	MYO15A	0.78
1782	Macrocephaly/autism syndrome	Enrichment	PTEN	0.78
1783	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	0.78
1784	Atrioventricular septal defect	Enrichment	BMP5	0.78
1785	Deafness, autosomal recessive 63	Enrichment	MYH9	0.78
1786	Chondrosarcoma, extraskeletal myxoid	Enrichment	TCF12	0.78
1787	Goldberg-shprintzen syndrome	Enrichment	FBN1	0.78
1788	Cholangitis, primary sclerosing	Enrichment	TCF4	0.78
1789	Congenital heart defects, multiple types, 4	Enrichment	BMP7	0.78
1790	Glanzmann thrombasthenia 2	Enrichment	ITGB3	0.78
1791	Muscular dystrophy, limb-girdle, autosomal recessive 23	Enrichment	LAMA2	0.78
1792	Pre-eclampsia	Enrichment	FLT1	0.78
1793	Heart conduction disease	Enrichment	FLNC	0.78
1794	Cardiac arrest	Enrichment	DSP	0.78
1795	Polycystic liver disease 1	Enrichment	FBN1	0.78
1796	Night blindness	Enrichment	EFEMP1	0.78
1797	Hemangioma	Enrichment	PTEN	0.78
1798	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	0.78
1799	Otof-related hearing loss	Enrichment	MYO15A	0.78
1800	Aplasia cutis congenita	Enrichment	ITGB4	0.78
1801	Coloboma of choroid and retina	Enrichment	ACTG1	0.78
1802	Severe congenital nemaline myopathy	Enrichment	ACTA1	0.78
1803	Migraine, familial hemiplegic, 1	Enrichment	CACNA1A	0.78
1804	Aniridia 1	Enrichment	PAX6	0.78
1805	Spinocerebellar ataxia 6	Enrichment	CACNA1A	0.78
1806	Aland island eye disease	Enrichment	CACNA1F	0.78
1807	Developmental and epileptic encephalopathy 2	Enrichment	CACNA1A	0.78
1808	Ventricular fibrillation, paroxysmal familial, 1	Enrichment	CACNA1C	0.78
1809	Developmental and epileptic encephalopathy 42	Enrichment	CACNA1A	0.78
1810	Cerebellar atrophy with seizures and variable developmental delay	Enrichment	CACNA2D2	0.78
1811	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	0.78
1812	Developmental and epileptic encephalopathy 52	Enrichment	CACNA1A	0.78
1813	Malignant hyperthermia	Enrichment	CACNA1S	0.78
1814	Episodic ataxia	Enrichment	CACNA1A	0.78
1815	Eyelid coloboma	Enrichment	PAX6	0.78
1816	Familial or sporadic hemiplegic migraine	Enrichment	CACNA1A	0.78
1817	Lens coloboma	Enrichment	PAX6	0.78
1818	Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-negative, nk cell-negative, due to adenosine deaminase deficiency	Enrichment	JAK3	0.77
1819	Pelvic organ prolapse	Enrichment	TAB2	0.77
1820	Retinoblastoma	Enrichment	RB1	0.77
1821	Waardenburg syndrome, type 2a	Enrichment	SOX10	0.77
1822	Nijmegen breakage syndrome	Enrichment	NBN	0.77
1823	Dysosteosclerosis	Enrichment	TNFRSF11A	0.77
1824	Myasthenic syndrome, congenital, 6, presynaptic	Enrichment	VHL	0.77
1825	Watson syndrome	Enrichment	NF1	0.77
1826	Pituitary hormone deficiency, combined, 2	Enrichment	SOX3	0.77
1827	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	0.77
1828	46,xx sex reversal 1	Enrichment	SOX9	0.77
1829	Severe combined immunodeficiency, x-linked	Enrichment	IL2RG	0.77
1830	Osteopetrosis, autosomal dominant 1	Enrichment	LRP5	0.77
1831	Osteoporosis, juvenile	Enrichment	WNT1	0.77
1832	Combined immunodeficiency, x-linked	Enrichment	IL2RG	0.77
1833	Hepatitis c virus	Enrichment	CCR5	0.77
1834	Intellectual developmental disorder, autosomal dominant 5	Enrichment	SYNGAP1	0.77
1835	Neurofibromatosis, familial spinal	Enrichment	NF1	0.77
1836	Holoprosencephaly 7	Enrichment	PTCH1	0.77
1837	Tuberous sclerosis 2	Enrichment	TSC2	0.77
1838	Cenani-lenz syndactyly syndrome	Enrichment	APC	0.77
1839	Woolly hair, autosomal recessive 3	Enrichment	RB1	0.77
1840	Chromosome 17q11.2 deletion syndrome, 1.4-mb	Enrichment	NF1	0.77
1841	Cortical dysplasia, complex, with other brain malformations 5	Enrichment	TUBB2A	0.77
1842	Hypotrichosis 8	Enrichment	RB1	0.77
1843	Koolen-de vries syndrome	Enrichment	ATM	0.77
1844	Wieacker-wolff syndrome	Enrichment	RASA1	0.77
1845	Nail disease	Enrichment	FZD6	0.77
1846	Inflammatory bowel disease 25	Enrichment	IL10RB	0.77
1847	Xanthinuria, type ii	Enrichment	TSC2	0.77
1848	Familial vesicoureteral reflux	Enrichment	SOX17	0.77
1849	Brain cancer	Enrichment	NF1	0.77
1850	Desmoplastic/nodular medulloblastoma	Enrichment	SUFU	0.77
1851	Butterfly-shaped pigment dystrophy	Enrichment	CTNNA1	0.77
1852	Colon adenocarcinoma	Enrichment	APC	0.77
1853	Adult-onset myasthenia gravis	Enrichment	TNFRSF11A	0.77
1854	Vogt-koyanagi-harada disease	Enrichment	FAS	0.77
1855	Cardiomyopathy, dilated, 1a	Enrichment	DSP, FLNC	0.77
1856	Centronuclear myopathy	Enrichment	ACTA1, CFL2	0.77
1857	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	TRAF6	0.76
1858	Mosaic variegated aneuploidy syndrome 1	Enrichment	PAK6	0.76
1859	Night blindness, congenital stationary, type 1c	Enrichment	GNAT1	0.76
1860	Follicular lymphoma	Enrichment	BCL2	0.76
1861	Lymphoma	Enrichment	TP53	0.76
1862	Autosomal dominant non-syndromic intellectual disability	Enrichment	CAMK2A, CAMK2B, ERBB4, GNB1, TCF4	0.75
1863	Microphthalmia/coloboma 12	Enrichment	FZD5, RARB	0.74
1864	Stereotypic movement disorder	Enrichment	SYNGAP1, TCF4	0.74
1865	Deafness, autosomal recessive	Enrichment	CDH23, MYH9, MYO15A, MYO7A	0.73
1866	Microcephaly 1, primary, autosomal recessive	Enrichment	ANGPT2	0.73
1867	Congenital nervous system abnormality	Enrichment	CAMK2B, CREBBP, CTNNB1, FGFR3, GNAO1, GNB5, PSEN1, PTEN, TSC2	0.73
1868	Nervous system disease	Enrichment	CAMK2B, CREBBP, CTNNB1, FGFR3, GNAO1, GNB5, PSEN1, PTEN, TSC2	0.73
1869	Williams-beuren syndrome	Enrichment	ELN, LIMK1	0.72
1870	Autosomal recessive nonsyndromic deafness	Enrichment	CDH23, MYH9, MYO15A, MYO7A	0.72
1871	Spondyloepiphyseal dysplasia with congenital joint dislocations	Enrichment	ACAN	0.71
1872	Glaucoma, primary open angle	Enrichment	LTBP2	0.71
1873	Developmental dysplasia of the hip 1	Enrichment	COL2A1	0.71
1874	Weyers acrofacial dysostosis	Enrichment	CTNNB1	0.71
1875	Moyamoya disease 1	Enrichment	ACTA2	0.71
1876	Usher syndrome, type id	Enrichment	CDH23	0.71
1877	Dental anomalies and short stature	Enrichment	LTBP3	0.71
1878	Deafness, autosomal recessive 12	Enrichment	CDH23	0.71
1879	Wiedemann-steiner syndrome	Enrichment	SMC3	0.71
1880	Mitochondrial dna depletion syndrome 1	Enrichment	TYMP	0.71
1881	Inflammatory myofibroblastic tumor	Enrichment	ALK	0.71
1882	Pain disorder	Enrichment	COL5A1	0.71
1883	Patent ductus arteriosus	Enrichment	FLNA	0.71
1884	Clear cell renal cell carcinoma	Enrichment	HNF1A	0.71
1885	Syndromic rod-cone dystrophy	Enrichment	CDH23	0.71
1886	Malaria	Enrichment	NOS2, TNF	0.71
1887	Attention deficit-hyperactivity disorder	Enrichment	GNB5, TCF20	0.71
1888	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	FGFR1, SOX11	0.69
1889	Heart disease	Enrichment	ABL1, CREBBP	0.69
1890	46,xy partial gonadal dysgenesis	Enrichment	SOS1, SOX9	0.69
1891	Episodic ataxia, type 2	Enrichment	CACNA1A	0.69
1892	Amblyopia	Enrichment	CACNA1F	0.69
1893	Autosomal recessive limb-girdle muscular dystrophy type 2b	Enrichment	CAPN3	0.69
1894	Congenital short qt syndrome	Enrichment	CACNA2D1	0.69
1895	Rare syndromic intellectual disability	Enrichment	UBTF	0.69
1896	Developmental and epileptic encephalopathy	Enrichment	CACNA1E, CACNA2D2, GNAO1	0.66
1897	Metachromatic leukodystrophy	Enrichment	GFAP	0.66
1898	Mirror movements 1	Enrichment	RAD51	0.66
1899	Polydactyly, preaxial ii	Enrichment	PTCH1	0.66
1900	Microphthalmia, syndromic 3	Enrichment	SOX2	0.66
1901	Hemophilia a	Enrichment	ACVRL1	0.66
1902	Budd-chiari syndrome	Enrichment	JAK2	0.66
1903	Paget disease of bone 2, early-onset	Enrichment	TNFRSF11A	0.66
1904	Immunodeficiency, common variable, 1	Enrichment	TNFRSF13B	0.66
1905	Lymphoproliferative syndrome 2	Enrichment	CD27	0.66
1906	Factor viii deficiency	Enrichment	ACVRL1	0.66
1907	Au-kline syndrome	Enrichment	VHL	0.66
1908	Lynch syndrome 4	Enrichment	RB1	0.66
1909	Dowling-degos disease	Enrichment	PSENEN	0.66
1910	Orofacial cleft	Enrichment	LRP6	0.66
1911	Hepatitis b	Enrichment	IL10RB	0.66
1912	Cerebrovascular disease	Enrichment	NOTCH3	0.66
1913	Adenosine deaminase deficiency	Enrichment	JAK3	0.66
1914	Hemoglobin c disease	Enrichment	CHEK2	0.66
1915	Paget's disease of bone 2	Enrichment	TNFRSF11A	0.66
1916	Primary hyperparathyroidism	Enrichment	CDKN1B	0.66
1917	Vitreoretinopathy	Enrichment	LRP5	0.66
1918	Orofacial clefting syndrome	Enrichment	LRP6	0.66
1919	Middle aortic syndrome	Enrichment	NF1	0.66
1920	Silver-russell syndrome 1	Enrichment	IGF2	0.65
1921	Usher syndrome, type iia	Enrichment	CDH23	0.65
1922	Megacolon	Enrichment	AKT3	0.65
1923	Epidermolysis bullosa simplex	Enrichment	ITGB4	0.65
1924	Myofibrillar myopathy	Enrichment	FLNC	0.65
1925	Childhood-onset nemaline myopathy	Enrichment	ACTA1	0.65
1926	Hypophosphatemic rickets	Enrichment	FGF23	0.65
1927	West syndrome	Enrichment	GNAO1, NTRK2, PLCB1	0.65
1928	Coloboma of macula	Enrichment	FZD5, RARB	0.65
1929	Coffin-siris syndrome 1	Enrichment	SOX11, SOX4	0.65
1930	Brachydactyly	Enrichment	GNAS	0.63
1931	Auditory neuropathy	Enrichment	CDH2, MYO7A	0.63
1932	Coloboma of optic nerve	Enrichment	PAX6	0.62
1933	Hypokalemic periodic paralysis, type 1	Enrichment	CACNA1S	0.62
1934	Muscular dystrophy, limb-girdle, autosomal recessive 1	Enrichment	CAPN3	0.62
1935	Childhood absence epilepsy	Enrichment	CACNA1H	0.62
1936	Fanconi anemia, complementation group c	Enrichment	FLNA	0.60
1937	Isolated growth hormone deficiency, type ia	Enrichment	GH1	0.60
1938	Mitochondrial dna depletion syndrome 4b	Enrichment	TYMP	0.60
1939	Lennox-gastaut syndrome	Enrichment	MAPK10	0.60
1940	Neuroblastoma	Enrichment	ALK	0.60
1941	Hypoplastic left heart syndrome	Enrichment	MYH6	0.60
1942	Childhood-onset schizophrenia	Enrichment	FREM2	0.60
1943	Early-onset posterior polar cataract	Enrichment	EPHA2	0.60
1944	Mosaic variegated aneuploidy syndrome	Enrichment	PAK6	0.58
1945	Hypothyroidism	Enrichment	GNB1	0.58
1946	Choreatic disease	Enrichment	GNAO1	0.58
1947	Permanent neonatal diabetes mellitus	Enrichment	STAT3	0.58
1948	Lymphoma, mucosa-associated lymphoid type	Enrichment	BIRC3	0.57
1949	Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1	Enrichment	NOTCH3	0.57
1950	Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative	Enrichment	JAK3	0.57
1951	Hypogonadotropic hypogonadism 1 with or without anosmia	Enrichment	SOX10	0.57
1952	Norrie disease	Enrichment	FZD4	0.57
1953	Breast-ovarian cancer, familial 2	Enrichment	BRCA1	0.57
1954	Chromosome 15q11.2 deletion syndrome	Enrichment	TUBG1	0.57
1955	Rubinstein-taybi syndrome 2	Enrichment	EP300	0.57
1956	Glioblastoma	Enrichment	ATM	0.57
1957	Persistent hyperplastic primary vitreous	Enrichment	FZD4	0.57
1958	Autosomal thrombocytopenia with normal platelets	Enrichment	CYCS	0.57
1959	Dementia	Enrichment	PSEN1	0.57
1960	Aggressive systemic mastocytosis	Enrichment	CBL	0.57
1961	Alzheimer disease, familial, 1	Enrichment	CSF1R, PSEN1	0.57
1962	Orofacial cleft 1	Enrichment	FGF10	0.56
1963	Cornelia de lange syndrome 1	Enrichment	SMC3	0.56
1964	Cardiomyopathy, familial hypertrophic, 4	Enrichment	MYH7	0.56
1965	Arrhythmogenic right ventricular dysplasia, familial, 9	Enrichment	DSP	0.56
1966	Congenital central hypoventilation syndrome	Enrichment	BDNF	0.56
1967	Cornelia de lange syndrome	Enrichment	SMC3	0.56
1968	Hypotrichosis simplex	Enrichment	CDH3	0.56
1969	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	TYMP	0.56
1970	Narcolepsy 1	Enrichment	TNFSF4	0.55
1971	Male infertility due to globozoospermia	Enrichment	SEPTIN4	0.55
1972	Body mass index quantitative trait locus 11	Enrichment	ADCY3, BDNF, GNAS	0.55
1973	Stargardt disease 1	Enrichment	COL18A1, COL2A1	0.54
1974	Nephrotic syndrome, type 1	Enrichment	PLCE1	0.54
1975	Developmental and epileptic encephalopathy 14	Enrichment	PLCB1	0.54
1976	Cone dystrophy	Enrichment	CACNA2D4, GNAT2	0.53
1977	Muscular dystrophy	Enrichment	CAPN3, COL6A2	0.53
1978	Long qt syndrome	Enrichment	DSP, MYH6	0.52
1979	Cat eye syndrome	Enrichment	ACTG1	0.52
1980	Cataract 30, multiple types	Enrichment	VIM	0.52
1981	Meier-gorlin syndrome 1	Enrichment	FGFR2	0.52
1982	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	0.52
1983	Myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency	Enrichment	MUSK	0.52
1984	Polymicrogyria	Enrichment	AKT3	0.52
1985	Alternating hemiplegia of childhood	Enrichment	CACNA1A	0.51
1986	Difference of sex development	Enrichment	CACNA1A	0.51
1987	Rheumatoid arthritis	Enrichment	IL10	0.51
1988	Chronic granulomatous disease	Enrichment	NCF2	0.51
1989	Klippel-trenaunay-weber syndrome	Enrichment	RASA1	0.51
1990	Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 1	Enrichment	TUBB2B	0.51
1991	Pierre robin syndrome	Enrichment	SOX9	0.51
1992	Waardenburg syndrome, type 4a	Enrichment	SOX10	0.51
1993	Hypertrichosis	Enrichment	CREBBP	0.51
1994	Waardenburg syndrome	Enrichment	SOX10	0.51
1995	Multicystic kidney dysplasia	Enrichment	FZD3	0.51
1996	Multicystic dysplastic kidney	Enrichment	FZD3	0.51
1997	Sporadic pheochromocytoma/secreting paraganglioma	Enrichment	VHL	0.51
1998	Familial colorectal cancer	Enrichment	TP53	0.50
1999	Usher syndrome	Enrichment	CDH23, MYO7A	0.48
2000	Diabetes mellitus	Enrichment	HNF1A	0.48
2001	Limb-girdle muscular dystrophy	Enrichment	CAPN3	0.47
2002	Movement disease	Enrichment	GNAO1	0.47
2003	Strabismus	Enrichment	CACNA1A, GNB1	0.47
2004	Dystonia	Enrichment	CAMK2B, GNAL, GNB1	0.45
2005	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	0.45
2006	Waardenburg syndrome, type 1	Enrichment	SOX10	0.45
2007	Coats disease	Enrichment	FZD4	0.45
2008	Polymicrogyria, bilateral perisylvian, x-linked	Enrichment	TUBB2B	0.45
2009	Semantic dementia	Enrichment	PSEN1	0.45
2010	Polycystic kidney disease 1	Enrichment	TSC2	0.45
2011	Congenital hydrocephalus	Enrichment	PTCH1	0.45
2012	Moyamoya angiopathy	Enrichment	ABL1	0.45
2013	Digeorge syndrome	Enrichment	HNF1A	0.45
2014	Cone-rod dystrophy 2	Enrichment	CACNA1F, CACNA2D4, IMPG2, ITGA4	0.44
2015	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	CSF1R, ERBB4, MEF2C	0.44
2016	Primary autosomal recessive microcephaly	Enrichment	ANGPT2, CIT	0.43
2017	Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly	Enrichment	COL5A1	0.43
2018	Clubfoot	Enrichment	COL5A1	0.43
2019	Visceral heterotaxy	Enrichment	ACVR2B, LEFTY2	0.42
2020	46 xx gonadal dysgenesis	Enrichment	BMP15	0.41
2021	Protein-deficiency anemia	Enrichment	NRAS	0.41
2022	Spermatogenic failure 5	Enrichment	AURKC	0.41
2023	Ewing sarcoma	Enrichment	NF1	0.41
2024	Severe congenital neutropenia	Enrichment	CSF3R	0.41
2025	Epilepsy, myoclonic juvenile	Enrichment	CACNB4	0.40
2026	Epilepsy, idiopathic generalized	Enrichment	CACNA1H	0.40
2027	Periventricular nodular heterotopia	Enrichment	FLNA	0.40
2028	Walker-warburg syndrome	Enrichment	COL4A1	0.40
2029	Generalized epilepsy with febrile seizures plus	Enrichment	FGF13	0.40
2030	Atypical hemolytic-uremic syndrome	Enrichment	COL4A5	0.38
2031	Muscular dystrophy, limb-girdle, autosomal recessive 2	Enrichment	CAPN3	0.37
2032	Tooth agenesis, selective, 1	Enrichment	BMPR2	0.37
2033	Neurofibromatosis, type i	Enrichment	NF1	0.37
2034	Myoclonic-atonic epilepsy	Enrichment	SYNGAP1	0.37
2035	Bilateral perisylvian polymicrogyria	Enrichment	TUBB2B	0.37
2036	Progressive non-fluent aphasia	Enrichment	PSEN1	0.37
2037	Behavioral variant of frontotemporal dementia	Enrichment	PSEN1	0.37
2038	Wolff-parkinson-white syndrome	Enrichment	MYH7	0.36
2039	Perrault syndrome 1	Enrichment	FBN1	0.36
2040	Complex neurodevelopmental disorder	Enrichment	MYH10, PPP2CA, RAC3, TCF20, TCF7L2	0.35
2041	Interstitial lung disease 2	Enrichment	DSP	0.34
2042	Cataract 44	Enrichment	EPHA2	0.34
2043	Aplastic anemia	Enrichment	NBN	0.34
2044	Autism	Enrichment	COL11A1, TCF20, TCF7L2	0.33
2045	Hypertension, essential	Enrichment	GNB3	0.32
2046	Polycystic kidney disease	Enrichment	COL4A4	0.32
2047	Early-onset nuclear cataract	Enrichment	EPHA2	0.32
2048	Nanophthalmos	Enrichment	SOX2	0.31
2049	Early infantile developmental and epileptic encephalopathy	Enrichment	GNAO1	0.31
2050	Charcot-marie-tooth disease	Enrichment	ARHGEF10, LAMA2	0.31
2051	Isolated congenital microcephaly	Enrichment	BRF1	0.28
2052	Congenital hypothyroidism	Enrichment	TUBB1	0.28
2053	Cardiomyopathy, dilated, 1g	Enrichment	DSP	0.26
2054	Premature menopause	Enrichment	NBN	0.26
2055	Multisystem inflammatory syndrome in children	Enrichment	IRAK3	0.25
2056	Seckel syndrome	Enrichment	ATR	0.24
2057	Familial atrial fibrillation	Enrichment	MYL4	0.24
2058	Autoinflammatory disease	Enrichment	TNFRSF1A	0.24
2059	Autosomal recessive limb-girdle muscular dystrophy	Enrichment	CAPN3	0.24
2060	Diamond-blackfan anemia 1	Enrichment	TP53	0.24
2061	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	0.22
2062	Male infertility with spermatogenesis disorder	Enrichment	AURKC	0.22
2063	Developmental and epileptic encephalopathy 1	Enrichment	GNAO1	0.21
2064	Retinitis pigmentosa	Enrichment	CDH23, CDH3, COL18A1, IMPG1, IMPG2, MERTK, MYO7A	0.20
2065	Long qt syndrome 1	Enrichment	DSP	0.18
2066	Autosomal recessive non-syndromic intellectual disability	Enrichment	CLIP1, EZR	0.17
2067	Cystic fibrosis	Enrichment	TGFB1	0.16
2068	Peripheral nervous system disease	Enrichment	NGF	0.16
2069	Neuropathy	Enrichment	NGF	0.16
2070	Spastic ataxia	Enrichment	CACNA1G, CACNB4	0.16
2071	Non-syndromic x-linked intellectual disability	Enrichment	ARHGEF6	0.14
2072	Diamond-blackfan anemia	Enrichment	TP53	0.13
2073	Primary ciliary dyskinesia	Enrichment	DRC4, PRKAR1B	0.11
2074	Benign epilepsy with centrotemporal spikes	Enrichment	PLCB1	0.10
2075	Centralopathic epilepsy	Enrichment	PLCB1	0.09
2076	Isolated joubert syndrome	Enrichment	SUFU	0.07
2077	Optic atrophy plus syndrome	Enrichment	CACNA1F	0.06
2078	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	FGF8	0.06
2079	Male infertility	Enrichment	SOX30	0.06
2080	Mitochondrial disease	Enrichment	GFER	0.02
2081	Leber plus disease	Enrichment	GDF6	0.01

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

ERK Signaling

Pathway Network for ERK Signaling

Pathway network for the ERK Signaling SuperPath

Member Pathways for ERK Signaling

Pathways in the ERK Signaling SuperPath

Gene overlap in member pathways for ERK Signaling SuperPath

Associated Genes for ERK Signaling

Associated Disorders for ERK Signaling

Disorders associated with ERK Signaling SuperPath

STRING Interaction Network for ERK Signaling

Sources for ERK Signaling