ERK Signaling SuperPath

Pathway network for ERK Signaling SuperPath
1180 Genes in the ERK Signaling SuperPath
ACAN ALK ANGPTL6 AREG AXL BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5
BMP6 BMP7 BMP8A BTC COL10A1 COL11A1 COL11A2 COL12A1 COL13A1 COL14A1 COL15A1 COL16A1
COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL27A1 COL2A1
COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2
COL6A3 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 HAPLN1 CSF1R VCAN NCAN SMC3
CCN2 CXCL12 DDR1 DDR2 EPYC LEFTY2 TYMP ECM1 ECM2 EFEMP1 EFEMP2 EGF
EGFR ELN EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3
EPHB4 EPHB6 EPOR ERBB2 ERBB3 ERBB4 FBN1 FBN2 FBN3 FGF1 FGF10 FGF11
FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23
FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 VEGFD FLT1 FLT3
FLT4 FN1 FOS FRAS1 GAS1 GAS2 GAS6 GAS8 GDF10 GDF2 GDF5 GDF6
GDF9 GFER GH1 GH2 GHRH GMFG GNRH1 GNRH2 GPC6 HAPLN2 HAPLN3 HAPLN4
HDGF HGF HSPG2 IGF1 IGF1R IGF2 IGF2-AS IL2 IL3 IL6 IL9 IMPG1
IMPG2 INSR INSRR ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3
ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JUN KDR COL20A1 KIT KITLG LAMA1 LAMA2
LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 LEFTY1 LHB
LIFR LMTK2 LMTK3 NRG4 LTBP1 LTBP2 LTBP3 LTBP4 MAPK1 MAPK3 MDK MEPE
MERTK MET MMRN2 MST1R MUSK NFKB1 NGF NRG1 NRG2 NRG3 NTF3 NTF4
NTRK1 NTRK2 NTRK3 NUDT6 OGN PIK3R5 PDGFA PDGFB PDGFC PDGFRA PDGFRB PENK
PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 GDF15 PLPP3 PPBP PRG2 PRG4 PROK1 PSIP1
PTK2 PTK2B PTK7 PTN RAC1 ROR1 ROR2 ROS1 RYK PDGFD CLEC11A SEMA3A
SEMA4B SEMA4G SEMA5A SPOCK1 SPOCK2 SPOCK3 SPON1 SPON2 SPP1 TBRG1 TDGF1 TEK
TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 KLF10 TIMP1 TIMP2 TIMP3 TIMP4 TNC
TNF TYRO3 UTS2 VEGFB VEGFC CDC42 MAPK10 MAPK8 MAPK9 MYC BCL2 ELK1
GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1
GNAT2 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2
GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 IL1A IL1B ITGA1 ITGA10 ITGA11
ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 LTA MAP2K1 MAP2K2
OSM PAK1 RAF1 RHOA RHOB RHOC RHOD RND3 RHOG ARHGEF6 RHOH DIRAS3
RND2 ATF1 ATF4 BAD CDH1 CHUK CREB1 CREB3 CREB3L4 RAC2 RAC3 RPS6KA4
RPS6KA5 TCF3 TCF4 TNFRSF1A ANGPT1 ANGPT2 ANGPT4 ANGPTL1 BAX BMP15 BMP8B BTK
CCL1 CCL11 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21
CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL4 CCL4L1 CCL4L2
CCL5 CCL7 CCL8 CD2 CD80 CER1 CSF1 CSF2 CSF3 CX3CL1 CXCL1 CXCL10
CXCL11 CXCL13 CXCL14 CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL9 DAP IL10 IL11
IL12A IL12B IL13 IL15 IL16 IL17A IL18 IL19 IL20 IL21 IL22 IL23A
IL24 IL26 IL4 IL5 IL7 CXCL8 LIF MAP2K3 MAP2K6 MAP2K7 PAK2 PAK3
PAK4 PAK6 PAK5 PF4 PF4V1 PIP PPBPP2 PRKCI PRKCZ TNFSF10 TNFSF11 TNFSF12
TNFSF13 TNFSF13B TNFSF14 TNFSF18 TNFSF4 CD40LG FASLG CD70 TNFSF8 TNFSF9 ADCY1 ADCY2
ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 BRAF GRB2 HRAS KRAS MRAS
NRAS PLCB1 PLCB2 PLCB3 PLCB4 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B
PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKD1 PRKD3 PRKCQ RAP1A RAP1B RRAS
RRAS2 SOS1 SOS2 SRC TP53 AKT1 AKT2 AKT3 ATF2 ATF3 ATF5 ATF6
ATF7 BCAR1 GCFC2 CASP3 CASP9 CCND1 CDH10 CDH11 CDH12 CDH13 CDH15 CDH16
CDH17 CDH18 CDH19 CDH2 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CEBPB
CFL1 CFL2 CTNNB1 MTOR GSK3A GSK3B HIF1A HNF4A IRS1 LEF1 MAPK6 MYL9
NFE2L1 PDPK1 PPP1R14B PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PTPA
PPP2R5A PPP2R5B PPP2R5C PPP2R5E PPP2R3B PTEN PXN HNF1A TCF12 TCF15 TCF19 HNF1B
TCF20 TCF21 TCF23 TCF7 TCF7L2 ZEB1 TEAD1 TEAD4 TFAM VIM ZNF354A ARHGEF1
ARHGEF10 ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF2 ARHGEF3 ARHGEF4 ARHGEF5 ARHGEF7 ARHGEF9 MAP2K4
MAP2K5 MAP3K10 MAP3K11 MCF2L MYLK NET1 PPP1R12A PPP1R12B ELK3 ELK4 IL1R1 IL2RA
MAP3K5 MAP3K7 MAPK11 MAPK12 MAPK13 MAPK14 MAPK7 MAX NFKBIA NGFR TGFBR1 TNFRSF1B
TRADD TUBB2A ARAF CNKSR1 LAMTOR3 MKNK1 MKNK2 PLCG1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6
STAT1 STAT3 ACTA1 ACTA2 ACTB ACTG1 ACTG2 ACTN1 ACTN2 ACTN3 ACTN4 RHOJ
RHOQ CDH20 CDH22 CDH23 CDH24 CDH26 DOCK1 DSP FBLIM1 FLNA FLNB FLNC
FOSB FOSL1 FOSL2 MYLPF ILK IRS2 IRS4 JUNB JUND MYH15 KRT18 LIMS1
LIMS2 CLEC18C MUC1 MYH1 MYH10 MYH11 MYH13 MYH14 MYH2 MYH3 MYH4 MYH6
MYH7 MYH7B MYH8 MYH9 MYL1 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7 MYO10
MYO15A MYO18B MYO1A MYO1B MYO1C MYO1D MYO1E MYO1F MYO1G MYO3A MYO3B MYO5A
MYO6 MYO7A MYO9A MYO9B NACA NCK2 NOS2 PARVA PARVB DCHS1 FERMT2 PPP2R5D
PTGS2 RSU1 SNAI1 SNAI2 TESK1 TGFB1I1 TMSB4X TMSB4Y VEGFA PABPC4-AS1 PCDH9-AS3 PCYT1B-AS1
ACTR2 ACTR3 ARFIP2 ARHGDIA ARHGDIB BAIAP2 SEPT7 CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42EP5
CIT CYFIP1 DES DIAPH3 GFAP IQGAP1 LIMK1 LIMK2 MAP3K9 SEPT9 MSN NCF2
SEPT2 PARD3 PARD6A PIP5K1A PIP5K1B PIP5K1C PIP4K2A PIP4K2B PIP4K2C PLD1 SEPT5 SEPT4
PKN1 RDX ROCK1 ROCK2 CLIP1 SLC9A1 STMN1 EZR WASF1 WASF3 WASL WIPF1
ABL1 ABL2 ACVR1 ACVR2B ACVRL1 ADAM17 APAF1 APC APH1A ATM ATR AURKB
AURKC AXIN1 BAK1 BBC3 BCL2L1 BCL2L11 BID BIRC2 BIRC3 CXCR5 BMPR1A BMPR1B
BMPR2 BRCA1 CAMK2A CAMK2B CAMK2D CAMK2G CASP10 CASP6 CASP7 CASP8 CBL CCND2
CCND3 CCNE1 CCNE2 CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9
CCRL2 CD28 CD4 CDK1 CDC25A CDC25B CDC25C CDK2 CDK4 CDK6 CDKN1A CDKN1B
CDKN2A CDKN2B CDKN2C CDKN2D CFLAR CHEK1 CHEK2 CREBBP CRK CSF2RA CSF2RB CSF3R
CTNNA1 CTNNA2 CTNNA3 CTNND1 CX3CR1 CXCR3 CXCR4 CXCR6 CYCS DHH DVL1 E2F1
E2F2 E2F3 E2F4 E2F5 EP300 FADD FANCD2 FOXO1 FPR2 FYN FZD1 FZD10
FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GAB1 GAB2 GLI1 GNB1L
RACK1 CCR10 HAT1 HIPK2 HRH4 IHH IL10RA IL10RB IL11RA IL12RB1 IL12RB2 IL13RA1
IL13RA2 IL15RA IL17RA IL17RC IL18R1 IL20RA IL22RA1 IL23R IL2RB IL2RG IL3RA IL4R
IL5RA IL6R IL7R CXCR1 CXCR2 IL9R JAK1 JAK2 JAK3 LRP5 LRP6 SMAD1
SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 TAB1 TAB2 MDM2 NBN NCSTN NF1 NFKBIB
NFKBIE NLK NOTCH1 NOTCH2 NOTCH3 NOTCH4 NUMB OSMR PSENEN PIK3C2G PIK3CG PMAIP1
PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PRKDC PSEN1 PSEN2 APH1B PTCH1
PTCH2 RAD51 RALA RALB RALBP1 RALGDS RAP2A RAP2B RAP2C RAPGEF1 RPTOR RARA
RARB RARG RASA1 RASGRF1 RASGRF2 RASGRP1 RASGRP2 RB1 RBL1 RBPJ RHEB NPTN
DIABLO SMO SOX1 SOX10 SOX11 SOX12 SOX13 SOX14 SOX15 SOX17 SOX18 SOX2
SOX21 SOX3 SOX30 SOX4 SOX5 SOX6 SOX7 SOX8 SOX9 STK11 STK36 AURKA
SUFU SYNGAP1 TGFBR2 TNFAIP6 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF11A TNFRSF25 TNFRSF12A TNFRSF13B
TNFRSF13C TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF21 TNFRSF4 CD40 FAS TNFRSF6B CD27 TNFRSF8 TNFRSF9
TSC1 TSC2 TUBA4A TUBA3C TUBA8 TUBB1 TUBB3 TUBB7P TUBD1 TUBE1 TUBG1 TUBG2
VHL WEE1 WNT1 WNT5A XCR1 BRF1 CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F
CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4
CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CAPN1 CAPN10 CAPN11 CAPN2
CAPN3 CAPN5 CAPN6 CAPN7 CAPN9 CAPNS1 CD3D CD3E CD3G CD247 DUSP1 DUSP3
ESR1 ESR2 ETS1 ETS2 H3F3A H3F3B HIST1H3A HIST1H3B HIST1H3C HIST1H3D HIST1H3E HIST1H3F
HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST3H3 HMGN1 LAT PAX6 PPP1R10 PPP1R11 PPP1R12C PPP1R13B
PPP1R14A PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7
PPP1R8 PPP1R9A PPP1R9B SRF TP53BP2 UBTF ZAP70 CLEC14A DDIT3 HBEGF GLG1 HSF1
IGF2R IL1R2 IRAK1 IRAK2 IRAK3 IRAK4 MAP3K2 MAP3K3 MAP3K4 MAP3K8 MAPK8IP1 MAPK8IP2
MAPK8IP3 MAPKAPK2 MEF2A MEF2C MEF2D NRP1 NRP2 OGFR PLCD1 PLCD3 PLCD4 PLCE1
PLCG2 PLCZ1 WNK1 RIPK1 SH3RF1 STAT2 STAT4 STAT5A STAT5B STAT6 TGFBR3 TLN1
TLN2 TRAF2 TRAF6 VCL
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for ERK Signaling SuperPath