Erythrocytes take up carbon dioxide and release oxygen

Pathway network for the Erythrocytes take up carbon dioxide and release oxygen SuperPath

Sources:

Reactome

Pathways in the Erythrocytes take up carbon dioxide and release oxygen SuperPath

#	Name	Source	Genes
1	Erythrocytes take up carbon dioxide and release oxygen	Reactome	AQP1 CA1 CA2 CA4 CYB5R1 CYB5R2 CYB5R4 CYB5RL HBA1 HBA2 HBB RHAG SLC4A1 (see all 13) (see less)
2	O2/CO2 exchange in erythrocytes	Reactome	AQP1 CA1 CA2 CA4 CYB5R1 CYB5R2 CYB5R4 CYB5RL HBA1 HBA2 HBB RHAG SLC4A1 (see all 13) (see less)
3	Erythrocytes take up oxygen and release carbon dioxide	Reactome	AQP1 CA1 CA2 CA4 HBA1 HBA2 HBB RHAG SLC4A1 (see all 9) (see less)
4	Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA)	Reactome	SLC4A1

Gene overlap in member pathways for Erythrocytes take up carbon dioxide and release oxygen SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SLC4A1	Solute Carrier Family 4 Member 1 (Diego Blood Group)	Protein Coding	4
2	HBA1	Hemoglobin Subunit Alpha 1	Protein Coding	3
3	HBA2	Hemoglobin Subunit Alpha 2	Protein Coding	3
4	HBB	Hemoglobin Subunit Beta	Protein Coding	3
5	AQP1	Aquaporin 1 (Colton Blood Group)	Protein Coding	3
6	RHAG	Rh Associated Glycoprotein	Protein Coding	3
7	CA1	Carbonic Anhydrase 1	Protein Coding	3
8	CA2	Carbonic Anhydrase 2	Protein Coding	3
9	CA4	Carbonic Anhydrase 4	Protein Coding	3
10	CYB5R4	Cytochrome B5 Reductase 4	Protein Coding	2
11	CYB5R2	Cytochrome B5 Reductase 2	Protein Coding	2
12	CYB5R1	Cytochrome B5 Reductase 1	Protein Coding	2
13	CYB5RL	Cytochrome B5 Reductase Like	Protein Coding	2

Disorders associated with Erythrocytes take up carbon dioxide and release oxygen SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hereditary spherocytosis	Direct
2	Renal tubular acidosis	Direct
3	Methemoglobinemia, beta type	Enrichment	HBA1, HBA2, HBB	8.39
4	Autosomal dominant secondary polycythemia	Enrichment	HBA1, HBA2, HBB	8.39
5	Heinz body anemias	Enrichment	HBA1, HBA2, HBB	7.95
6	Heinz body anemia	Enrichment	HBA1, HBA2, HBB	7.95
7	Alpha-thalassemia	Enrichment	HBA1, HBA2, HBB	7.77
8	Protein-deficiency anemia	Enrichment	HBA1, HBA2, HBB	7.24
9	Alpha thalassemia-intellectual disability syndrome type 1	Enrichment	HBA1, HBA2	5.93
10	Erythrocytosis, familial, 7	Enrichment	HBA1, HBA2	5.63
11	Hemoglobin h disease	Enrichment	HBA1, HBA2	5.63
12	Thalassemia	Enrichment	HBA2, HBB	5.41
13	Beta-thalassemia	Enrichment	HBA2, HBB	5.09
14	Beta-thalassemia major	Enrichment	HBA2, HBB	5.09
15	Malaria	Enrichment	HBB, SLC4A1	4.01
16	Hydrops fetalis, nonimmune	Enrichment	HBA1, HBA2	3.90
17	Overhydrated hereditary stomatocytosis	Enrichment	RHAG	3.18
18	Rh-null, regulator type	Enrichment	RHAG	3.18
19	Retinitis pigmentosa 17	Enrichment	CA4	3.18
20	Blood group, diego system	Enrichment	SLC4A1	3.18
21	Ovalocytosis, southeast asian	Enrichment	SLC4A1	3.18
22	Blood group--wright antigen	Enrichment	SLC4A1	3.18
23	Spherocytosis, type 4	Enrichment	SLC4A1	3.18
24	Blood group, colton system	Enrichment	AQP1	3.18
25	Cryohydrocytosis	Enrichment	SLC4A1	3.18
26	Blood group--swann system	Enrichment	SLC4A1	3.18
27	Sickle cell-beta-thalassemia disease syndrome	Enrichment	HBB	3.18
28	Hemoglobin c-beta-thalassemia syndrome	Enrichment	HBB	3.18
29	Sickle cell s-o arab disease	Enrichment	HBB	3.18
30	Sickle cell-beta zero-thalassemia	Enrichment	HBB	3.18
31	Sickle cell s-d punjab disease	Enrichment	HBB	3.18
32	Sickle cell s-c disease	Enrichment	HBB	3.18
33	Sickle cell s-e disease	Enrichment	HBB	3.18
34	Homozygous hemoglobin o arab disease	Enrichment	HBB	3.18
35	Sickle cell s-other specified hemoglobin variant	Enrichment	HBB	3.18
36	Methemoglobinemia, alpha type	Enrichment	HBA1	2.88
37	Osteopetrosis, autosomal recessive 3	Enrichment	CA2	2.88
38	Hemoglobin lepore-beta-thalassemia syndrome	Enrichment	HBB	2.88
39	Renal tubular acidosis, distal, 4, with hemolytic anemia	Enrichment	SLC4A1	2.88
40	Sickle cell s-lepore disease	Enrichment	HBB	2.88
41	Hemoglobin e disease	Enrichment	HBB	2.70
42	Hemolytic disease of fetus and newborn, rh-induced	Enrichment	RHAG	2.70
43	Sickle cell-hemoglobin c disease	Enrichment	HBB	2.70
44	Hemoglobin d disease	Enrichment	HBB	2.70
45	Delta beta-thalassemia	Enrichment	HBB	2.70
46	Unstable hemoglobin disease	Enrichment	HBB	2.70
47	Hemoglobin e/beta thalassemia disease	Enrichment	HBB	2.70
48	Dehydrated hereditary stomatocytosis 1 with or without pseudohyperkalemia and/or perinatal edema	Enrichment	SLC4A1	2.58
49	Sickle cell disease	Enrichment	HBB	2.58
50	Beta-thalassemia, dominant inclusion body type	Enrichment	HBB	2.58
51	Erythrocytosis, familial, 6	Enrichment	HBB	2.58
52	Beta-thalassemia intermedia	Enrichment	HBB	2.58
53	Hemoglobinopathy	Enrichment	HBB	2.58
54	Hemoglobin c disease	Enrichment	HBB	2.58
55	Hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome	Enrichment	HBB	2.58
56	Methemoglobinemia, beta-globin type	Enrichment	HBB	2.58
57	Osteopetrosis	Enrichment	CA2	2.48
58	Hereditary persistence of fetal hemoglobin-sickle cell disease syndrome	Enrichment	HBB	2.48
59	Renal tubular acidosis, distal, 1	Enrichment	SLC4A1	2.40
60	Autosomal recessive distal renal tubular acidosis	Enrichment	SLC4A1	2.40
61	Distal renal tubular acidosis	Enrichment	SLC4A1	2.40
62	Hemolytic anemia	Enrichment	HBB	2.33
63	Fetal hemoglobin quantitative trait locus 1	Enrichment	HBB	2.28
64	Atypical hemolytic-uremic syndrome	Enrichment	HBB	2.00
65	Non-immune hydrops fetalis	Enrichment	HBA2	1.69
66	Retinitis pigmentosa	Enrichment	CA4	0.88
67	Hereditary retinal dystrophy	Enrichment	CA4	0.75
68	Fundus dystrophy	Enrichment	CA4	0.75

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Erythrocytes take up carbon dioxide and release oxygen

Pathway Network for Erythrocytes take up carbon dioxide and release oxygen

Pathway network for the Erythrocytes take up carbon dioxide and release oxygen SuperPath

Member Pathways for Erythrocytes take up carbon dioxide and release oxygen

Pathways in the Erythrocytes take up carbon dioxide and release oxygen SuperPath

Gene overlap in member pathways for Erythrocytes take up carbon dioxide and release oxygen SuperPath

Associated Genes for Erythrocytes take up carbon dioxide and release oxygen

Associated Disorders for Erythrocytes take up carbon dioxide and release oxygen

Disorders associated with Erythrocytes take up carbon dioxide and release oxygen SuperPath

STRING Interaction Network for Erythrocytes take up carbon dioxide and release oxygen

Sources for Erythrocytes take up carbon dioxide and release oxygen