Estrogen metabolism

No Pathway Network information available for Estrogen metabolism

Pathways in the Estrogen metabolism SuperPath

#	Name	Source	Genes
1	Estrogen metabolism	WikiPathways	ARSD ARSL COMT CYP1A1 CYP1A2 CYP1B1 CYP3A4 GSTA1 GSTM1 NQO1 STS SULT1A1 SULT1E1 UGT1A1 UGT1A3 UGT1A6 UGT1A9 UGT2B7 (see all 18) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ARSD	Arylsulfatase D	Protein Coding	1
2	UGT2B7	UDP Glucuronosyltransferase Family 2 Member B7	Protein Coding	1
3	SULT1A1	Sulfotransferase Family 1A Member 1	Protein Coding	1
4	SULT1E1	Sulfotransferase Family 1E Member 1	Protein Coding	1
5	UGT1A3	UDP Glucuronosyltransferase Family 1 Member A3	Protein Coding	1
6	UGT1A1	UDP Glucuronosyltransferase Family 1 Member A1	Protein Coding	1
7	UGT1A9	UDP Glucuronosyltransferase Family 1 Member A9	Protein Coding	1
8	UGT1A6	UDP Glucuronosyltransferase Family 1 Member A6	Protein Coding	1
9	ARSL	Arylsulfatase L	Protein Coding	1
10	STS	Steroid Sulfatase	Protein Coding	1
11	GSTM1	Glutathione S-Transferase Mu 1	Protein Coding	1
12	GSTA1	Glutathione S-Transferase Alpha 1	Protein Coding	1
13	NQO1	NAD(P)H Quinone Dehydrogenase 1	Protein Coding	1
14	CYP3A4	Cytochrome P450 Family 3 Subfamily A Member 4	Protein Coding	1
15	CYP1B1	Cytochrome P450 Family 1 Subfamily B Member 1	Protein Coding	1
16	CYP1A2	Cytochrome P450 Family 1 Subfamily A Member 2	Protein Coding	1
17	CYP1A1	Cytochrome P450 Family 1 Subfamily A Member 1	Protein Coding	1
18	COMT	Catechol-O-Methyltransferase	Protein Coding	1

Disorders associated with Estrogen metabolism SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Crigler-najjar syndrome, type i	Enrichment	UGT1A1, UGT1A3, UGT1A6, UGT1A9	9.35
2	Hyperbilirubinemia, transient familial neonatal	Enrichment	UGT1A1, UGT1A3, UGT1A6, UGT1A9	9.35
3	Bilirubin, serum level of, quantitative trait locus 1	Enrichment	UGT1A1, UGT1A3, UGT1A6, UGT1A9	9.35
4	Crigler-najjar syndrome, type ii	Enrichment	UGT1A1, UGT1A3, UGT1A6, UGT1A9	9.35
5	Gilbert syndrome	Enrichment	UGT1A1, UGT1A3, UGT1A6, UGT1A9	9.14
6	Bilirubin metabolic disorder	Enrichment	UGT1A1, UGT1A3, UGT1A6, UGT1A9	9.14
7	Chondrodysplasia punctata, brachytelephalangic, autosomal	Enrichment	ARSL	2.88
8	Chondrodysplasia punctata 1, x-linked recessive	Enrichment	ARSL	2.88
9	Vitamin d-dependent rickets, type 3	Enrichment	CYP3A4	2.88
10	X-linked chondrodysplasia punctata 1	Enrichment	ARSL	2.88
11	Catechol-o-methyltransferase activity, variation in	Enrichment	COMT	2.88
12	Syndromic recessive x-linked ichthyosis	Enrichment	STS	2.88
13	Glaucoma 1, open angle, a	Enrichment	CYP1B1	2.58
14	Anterior segment dysgenesis 6	Enrichment	CYP1B1	2.58
15	Ichthyosis, x-linked	Enrichment	STS	2.58
16	Primary congenital glaucoma	Enrichment	CYP1B1	2.58
17	Glaucoma 3, primary infantile, b	Enrichment	CYP1B1	2.28
18	Juvenile glaucoma	Enrichment	CYP1B1	2.18
19	Glaucoma, primary open angle	Enrichment	CYP1B1	2.10
20	Anterior segment dysgenesis 5	Enrichment	CYP1B1	2.10
21	Glaucoma 3, primary congenital, a	Enrichment	CYP1B1	2.03
22	Peters-plus syndrome	Enrichment	CYP1B1	1.88
23	Digeorge syndrome	Enrichment	COMT	1.80
24	Coffin-siris syndrome 1	Enrichment	ARSL	1.70
25	Anterior segment dysgenesis	Enrichment	CYP1B1	1.70
26	Bardet-biedl syndrome	Enrichment	COMT	1.27
27	Schizophrenia	Enrichment	COMT	1.12

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Estrogen metabolism

Pathway Network for Estrogen metabolism

Member Pathways for Estrogen metabolism

Pathways in the Estrogen metabolism SuperPath

Associated Genes for Estrogen metabolism

Associated Disorders for Estrogen metabolism

Disorders associated with Estrogen metabolism SuperPath

STRING Interaction Network for Estrogen metabolism

Sources for Estrogen metabolism