Ethanol metabolism production of ROS by CYP2E1

No Pathway Network information available for Ethanol metabolism production of ROS by CYP2E1

#	Name	Source	Genes
1	Ethanol metabolism production of ROS by CYP2E1	WikiPathways	CYP2E1 MAFF MAFG MAFK MAP2K1 MAP2K2 MAPK8 NFE2L2 SP1 (see all 9) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SP1	Sp1 Transcription Factor	Protein Coding	1
2	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	1
3	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
4	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	1
5	NFE2L2	NFE2 Like BZIP Transcription Factor 2	Protein Coding	1
6	MAFG	MAF BZIP Transcription Factor G	Protein Coding	1
7	MAFF	MAF BZIP Transcription Factor F	Protein Coding	1
8	CYP2E1	Cytochrome P450 Family 2 Subfamily E Member 1	Protein Coding	1
9	MAFK	MAF BZIP Transcription Factor K	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1, MAP2K2	5.63
2	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1, MAP2K2	5.63
3	Noonan syndrome and noonan-related syndrome	Enrichment	MAP2K1, MAP2K2	4.39
4	Noonan syndrome 1	Enrichment	MAP2K1, MAP2K2	4.01
5	Rasopathy	Enrichment	MAP2K1, MAP2K2	3.90
6	Melorheostosis, isolated	Enrichment	MAP2K1	3.18
7	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	3.18
8	Immunodeficiency, developmental delay, and hypohomocysteinemia	Enrichment	NFE2L2	3.18
9	Melorheostosis	Enrichment	MAP2K1	3.18
10	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	3.18
11	Tafro syndrome	Enrichment	MAP2K2	2.88
12	Langerhans cell histiocytosis	Enrichment	MAP2K1	2.70
13	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	2.58
14	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1	2.33
15	Arteriovenous malformation	Enrichment	MAP2K1	2.22
16	Myopathy, x-linked, with excessive autophagy	Enrichment	MAP2K1	2.18
17	Lung non-small cell carcinoma	Enrichment	MAP2K1	2.14
18	Lung cancer	Enrichment	NFE2L2	1.68
19	Colorectal cancer	Enrichment	NFE2L2	1.25
20	Autism spectrum disorder	Enrichment	MAP2K1	1.15

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Ethanol metabolism production of ROS by CYP2E1