fatty acid α-oxidation
Pathways in the fatty acid α-oxidation SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | fatty acid α-oxidation | PubChem | |
| 2 | fatty acid α-oxidation II | PubChem | |
| 3 | fatty acid α-oxidation III | PubChem |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | ALDH3A2 | Aldehyde Dehydrogenase 3 Family Member A2 | Protein Coding | 3 |
| 2 | HACL1 | 2-Hydroxyacyl-CoA Lyase 1 | Protein Coding | 3 |
| 3 | PHYH | Phytanoyl-CoA 2-Hydroxylase | Protein Coding | 2 |
| 4 | SLC27A2 | Solute Carrier Family 27 Member 2 | Protein Coding | 2 |
| 5 | FA2H | Fatty Acid 2-Hydroxylase | Protein Coding | 1 |
Disorders associated with fatty acid α-oxidation SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Spastic paraplegia 35, autosomal recessive, with or without neurodegeneration | Enrichment | FA2H | 3.35 |
| 2 | Sjogren-larsson syndrome | Enrichment | ALDH3A2 | 3.35 |
| 3 | Hereditary spastic paraplegia 35 | Enrichment | FA2H | 3.35 |
| 4 | Refsum disease, classic | Enrichment | PHYH | 3.05 |
| 5 | Neurodegeneration with brain iron accumulation | Enrichment | FA2H | 2.66 |
| 6 | Orofacial cleft 1 | Enrichment | PHYH | 2.58 |
| 7 | Cerebral palsy | Enrichment | ALDH3A2 | 2.07 |
| 8 | Hereditary spastic paraplegia | Enrichment | FA2H | 2.03 |
| 9 | Spastic ataxia | Enrichment | FA2H | 1.93 |
| 10 | Retinitis pigmentosa | Enrichment | PHYH | 1.21 |
| 11 | Hereditary retinal dystrophy | Enrichment | PHYH | 1.08 |
| 12 | Fundus dystrophy | Enrichment | PHYH | 1.08 |
