Fatty acid biosynthesis

No Pathway Network information available for Fatty acid biosynthesis

#	Name	Source	Genes
1	Fatty acid biosynthesis	WikiPathways	ACAA2 ACACA ACACB ACLY ACSL1 ACSL3 ACSL4 ACSL5 ACSL6 ACSS2 DECR1 ECH1 ECHDC1 ECHDC2 ECHDC3 ECHS1 FASN HADH MECR PC PECR SCD (see all 22) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACSS2	Acyl-CoA Synthetase Short Chain Family Member 2	Protein Coding	1
2	ACSL3	Acyl-CoA Synthetase Long Chain Family Member 3	Protein Coding	1
3	SCD	Stearoyl-CoA Desaturase	Protein Coding	1
4	ECHDC1	Ethylmalonyl-CoA Decarboxylase 1	Protein Coding	1
5	PECR	Peroxisomal Trans-2-Enoyl-CoA Reductase	Protein Coding	1
6	ACSL5	Acyl-CoA Synthetase Long Chain Family Member 5	Protein Coding	1
7	MECR	Mitochondrial Trans-2-Enoyl-CoA Reductase	Protein Coding	1
8	PC	Pyruvate Carboxylase	Protein Coding	1
9	ACLY	ATP Citrate Lyase	Protein Coding	1
10	ACACB	Acetyl-CoA Carboxylase Beta	Protein Coding	1
11	ACACA	Acetyl-CoA Carboxylase Alpha	Protein Coding	1
12	HADH	Hydroxyacyl-CoA Dehydrogenase	Protein Coding	1
13	ACSL6	Acyl-CoA Synthetase Long Chain Family Member 6	Protein Coding	1
14	FASN	Fatty Acid Synthase	Protein Coding	1
15	ACSL4	Acyl-CoA Synthetase Long Chain Family Member 4	Protein Coding	1
16	ACSL1	Acyl-CoA Synthetase Long Chain Family Member 1	Protein Coding	1
17	ECHS1	Enoyl-CoA Hydratase, Short Chain 1	Protein Coding	1
18	DECR1	2,4-Dienoyl-CoA Reductase 1	Protein Coding	1
19	ACAA2	Acetyl-CoA Acyltransferase 2	Protein Coding	1
20	ECH1	Enoyl-CoA Hydratase 1	Protein Coding	1
21	ECHDC3	Enoyl-CoA Hydratase Domain Containing 3	Protein Coding	1
22	ECHDC2	Enoyl-CoA Hydratase Domain Containing 2	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	3-hydroxyacyl-coa dehydrogenase deficiency	Enrichment	HADH	2.79
2	Intellectual developmental disorder, x-linked 63	Enrichment	ACSL4	2.79
3	Optic atrophy 16	Enrichment	MECR	2.79
4	Diarrhea 13	Enrichment	ACSL5	2.79
5	Acetyl-coa carboxylase-alpha deficiency	Enrichment	ACACA	2.79
6	Dystonia, childhood-onset, with optic atrophy and basal ganglia abnormalities	Enrichment	MECR	2.79
7	Acyl-coa dehydrogenase, short-chain, deficiency of	Enrichment	ECHDC1	2.49
8	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	HADH	2.49
9	Mitochondrial short-chain enoyl-coa hydratase 1 deficiency	Enrichment	ECHS1	2.49
10	Pyruvate carboxylase deficiency	Enrichment	PC	2.31
11	Hyperinsulinemic hypoglycemia	Enrichment	HADH	2.31
12	Amme complex	Enrichment	ACSL4	2.19
13	Hyperinsulinemic hypoglycemia, familial, 1	Enrichment	HADH	2.01
14	Nonsyndromic genetic hyperinsulinism	Enrichment	HADH	2.01
15	Orofacial cleft 1	Enrichment	ACSS2	1.84
16	Stroke, ischemic	Enrichment	ACSL4	1.79
17	Non-syndromic x-linked intellectual disability	Enrichment	ACSL4	1.25
18	Optic atrophy plus syndrome	Enrichment	MECR	1.16
19	Leigh syndrome, nuclear	Enrichment	ECHS1	0.97
20	Leigh disease	Enrichment	ECHS1	0.93
21	Mitochondrial disease	Enrichment	MECR	0.88

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Fatty acid biosynthesis