Fatty acyl-CoA biosynthesis

No Pathway Network information available for Fatty acyl-CoA biosynthesis

Pathways in the Fatty acyl-CoA biosynthesis SuperPath

#	Name	Source	Genes
1	Fatty acyl-CoA biosynthesis	Reactome	ACACA ACLY ACSBG1 ACSBG2 ACSF3 ACSL1 ACSL3 ACSL4 ACSL5 ACSL6 CBR4 ELOVL1 ELOVL2 ELOVL3 ELOVL4 ELOVL5 ELOVL6 ELOVL7 FASN HACD1 HACD2 HACD3 HACD4 HSD17B12 HSD17B3 HSD17B8 HTD2 MORC2 OLAH PPT1 PPT2 SCD SCD5 SLC27A2 SLC27A3 TECR TECRL (see all 37) (see less)
2	Synthesis of very long-chain fatty acyl-CoAs	Reactome	ACSBG1 ACSBG2 ACSF3 ACSL1 ACSL3 ACSL4 ACSL5 ACSL6 ELOVL1 ELOVL2 ELOVL3 ELOVL4 ELOVL5 ELOVL6 ELOVL7 HACD1 HACD2 HACD3 HACD4 HSD17B12 HSD17B3 SLC27A3 TECR TECRL (see all 24) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SLC27A3	Solute Carrier Family 27 Member 3	Protein Coding	2
2	ACSF3	Acyl-CoA Synthetase Family Member 3	Protein Coding	2
3	HACD2	3-Hydroxyacyl-CoA Dehydratase 2	Protein Coding	2
4	ACSL1	Acyl-CoA Synthetase Long Chain Family Member 1	Protein Coding	2
5	ACSL3	Acyl-CoA Synthetase Long Chain Family Member 3	Protein Coding	2
6	ACSL4	Acyl-CoA Synthetase Long Chain Family Member 4	Protein Coding	2
7	ACSBG1	Acyl-CoA Synthetase Bubblegum Family Member 1	Protein Coding	2
8	ACSL6	Acyl-CoA Synthetase Long Chain Family Member 6	Protein Coding	2
9	TECRL	Trans-2,3-Enoyl-CoA Reductase Like	Protein Coding	2
10	HSD17B3	Hydroxysteroid 17-Beta Dehydrogenase 3	Protein Coding	2
11	HACD4	3-Hydroxyacyl-CoA Dehydratase 4	Protein Coding	2
12	HSD17B12	Hydroxysteroid 17-Beta Dehydrogenase 12	Protein Coding	2
13	HACD3	3-Hydroxyacyl-CoA Dehydratase 3	Protein Coding	2
14	ACSL5	Acyl-CoA Synthetase Long Chain Family Member 5	Protein Coding	2
15	ELOVL2	ELOVL Fatty Acid Elongase 2	Protein Coding	2
16	ELOVL5	ELOVL Fatty Acid Elongase 5	Protein Coding	2
17	ELOVL1	ELOVL Fatty Acid Elongase 1	Protein Coding	2
18	ELOVL4	ELOVL Fatty Acid Elongase 4	Protein Coding	2
19	ELOVL6	ELOVL Fatty Acid Elongase 6	Protein Coding	2
20	ELOVL7	ELOVL Fatty Acid Elongase 7	Protein Coding	2
21	ACSBG2	Acyl-CoA Synthetase Bubblegum Family Member 2	Protein Coding	2
22	ELOVL3	ELOVL Fatty Acid Elongase 3	Protein Coding	2
23	HACD1	3-Hydroxyacyl-CoA Dehydratase 1	Protein Coding	2
24	TECR	Trans-2,3-Enoyl-CoA Reductase	Protein Coding	2
25	HTD2	Hydroxyacyl-Thioester Dehydratase Type 2	Protein Coding	1
26	SLC27A2	Solute Carrier Family 27 Member 2	Protein Coding	1
27	FASN	Fatty Acid Synthase	Protein Coding	1
28	MORC2	MORC Family CW-Type Zinc Finger 2	Protein Coding	1
29	ACACA	Acetyl-CoA Carboxylase Alpha	Protein Coding	1
30	ACLY	ATP Citrate Lyase	Protein Coding	1
31	OLAH	Oleoyl-ACP Hydrolase	Protein Coding	1
32	PPT1	Palmitoyl-Protein Thioesterase 1	Protein Coding	1
33	SCD	Stearoyl-CoA Desaturase	Protein Coding	1
34	HSD17B8	Hydroxysteroid 17-Beta Dehydrogenase 8	Protein Coding	1
35	SCD5	Stearoyl-CoA Desaturase 5	Protein Coding	1
36	CBR4	Carbonyl Reductase 4	Protein Coding	1
37	PPT2	Palmitoyl-Protein Thioesterase 2	Protein Coding	1

Disorders associated with Fatty acyl-CoA biosynthesis SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Intellectual developmental disorder, x-linked 63	Enrichment	ACSL4	2.75
2	Spinocerebellar ataxia 34	Enrichment	ELOVL4	2.75
3	Ventricular tachycardia, catecholaminergic polymorphic, 3	Enrichment	TECRL	2.75
4	Intellectual developmental disorder, autosomal recessive 14	Enrichment	TECR	2.75
5	Congenital myopathy 11	Enrichment	HACD1	2.75
6	Diarrhea 13	Enrichment	ACSL5	2.75
7	Spinocerebellar ataxia 38	Enrichment	ELOVL5	2.75
8	Ichthyosis, spastic quadriplegia, and impaired intellectual development	Enrichment	ELOVL4	2.75
9	Acetyl-coa carboxylase-alpha deficiency	Enrichment	ACACA	2.56
10	Deafness, autosomal dominant 79	Enrichment	SCD5	2.56
11	Developmental delay, impaired growth, dysmorphic facies, and axonal neuropathy	Enrichment	MORC2	2.56
12	Charcot-marie-tooth disease, axonal, type 2z	Enrichment	MORC2	2.56
13	Stargardt disease 3	Enrichment	ELOVL4	2.45
14	Combined malonic and methylmalonic aciduria	Enrichment	ACSF3	2.45
15	17-beta hydroxysteroid dehydrogenase iii deficiency	Enrichment	HSD17B3	2.45
16	Ichthyotic keratoderma, spasticity, hypomyelination, and dysmorphic facial features	Enrichment	ELOVL1	2.45
17	Ceroid lipofuscinosis, neuronal, 1	Enrichment	PPT1	2.26
18	Amme complex	Enrichment	ACSL4	2.15
19	Pseudohermaphroditism	Enrichment	HSD17B3	2.05
20	Spastic ataxia	Enrichment	ELOVL4, PPT1	2.04
21	Isolated methylmalonic acidemia	Enrichment	ACSF3	1.91
22	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	TECRL	1.85
23	Methylmalonic acidemia	Enrichment	ACSF3	1.85
24	Difference of sex development	Enrichment	HSD17B3	1.85
25	Stroke, ischemic	Enrichment	ACSL4	1.76
26	Epilepsy, myoclonic juvenile	Enrichment	HSD17B3	1.71
27	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	PPT1	1.61
28	Congenital myopathy 4a, autosomal dominant	Enrichment	HACD1	1.58
29	Neuronal ceroid lipofuscinosis	Enrichment	PPT1	1.40
30	Stargardt disease 1	Enrichment	ELOVL4	1.29
31	Long qt syndrome	Enrichment	TECRL	1.27
32	Non-syndromic x-linked intellectual disability	Enrichment	ACSL4	1.21
33	Autosomal recessive non-syndromic intellectual disability	Enrichment	TECR	1.01
34	Congenital nervous system abnormality	Enrichment	PPT1	0.60
35	Nervous system disease	Enrichment	PPT1	0.60
36	Hereditary retinal dystrophy	Enrichment	ELOVL4	0.39
37	Fundus dystrophy	Enrichment	ELOVL4	0.39
38	Retinitis pigmentosa	Enrichment	PPT1	0.35

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Fatty acyl-CoA biosynthesis

Pathway Network for Fatty acyl-CoA biosynthesis

Member Pathways for Fatty acyl-CoA biosynthesis

Pathways in the Fatty acyl-CoA biosynthesis SuperPath

Associated Genes for Fatty acyl-CoA biosynthesis

Associated Disorders for Fatty acyl-CoA biosynthesis

Disorders associated with Fatty acyl-CoA biosynthesis SuperPath

STRING Interaction Network for Fatty acyl-CoA biosynthesis

Sources for Fatty acyl-CoA biosynthesis