FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma

No Pathway Network information available for FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma

Pathways in the FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma SuperPath

#	Name	Source	Genes
1	FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma	WikiPathways	BCL6 BCOR DUSP6 EED EZH2 H2AB1 H2AB2 H2AB3 H2AJ H2AX H2AZ1 H2AZ2 H3-3A H3-3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C4 H3C6 H3C7 H3C8 KDM2B MACROH2A1 MACROH2A2 MAPK1 MAPK3 PCGF1 RNF2 SUZ12 (see all 33) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	EED	Embryonic Ectoderm Development	Protein Coding	1
2	KDM2B	Lysine Demethylase 2B	Protein Coding	1
3	BCL6	BCL6 Transcription Repressor	Protein Coding	1
4	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
5	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
6	BCOR	BCL6 Corepressor	Protein Coding	1
7	H3-3B	H3.3 Histone B	Protein Coding	1
8	H3-3A	H3.3 Histone A	Protein Coding	1
9	H2AX	H2A.X Variant Histone	Protein Coding	1
10	SUZ12	SUZ12 Polycomb Repressive Complex 2 Subunit	Protein Coding	1
11	EZH2	Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit	Protein Coding	1
12	DUSP6	Dual Specificity Phosphatase 6	Protein Coding	1
13	MACROH2A1	MacroH2A.1 Histone	Protein Coding	1
14	H2AZ2	H2A.Z Variant Histone 2	Protein Coding	1
15	H3C7	H3 Clustered Histone 7	Protein Coding	1
16	PCGF1	Polycomb Group Ring Finger 1	Protein Coding	1
17	H3C14	H3 Clustered Histone 14	Protein Coding	1
18	H2AB3	H2A.B Variant Histone 3	Protein Coding	1
19	H3C10	H3 Clustered Histone 10	Protein Coding	1
20	H3C12	H3 Clustered Histone 12	Protein Coding	1
21	H3C8	H3 Clustered Histone 8	Protein Coding	1
22	H3C11	H3 Clustered Histone 11	Protein Coding	1
23	H3C6	H3 Clustered Histone 6	Protein Coding	1
24	H3C4	H3 Clustered Histone 4	Protein Coding	1
25	H3C1	H3 Clustered Histone 1	Protein Coding	1
26	H3C13	H3 Clustered Histone 13	Protein Coding	1
27	RNF2	Ring Finger Protein 2	Protein Coding	1
28	H2AJ	H2A.J Histone	Protein Coding	1
29	MACROH2A2	MacroH2A.2 Histone	Protein Coding	1
30	H2AB1	H2A.B Variant Histone 1	Protein Coding	1
31	H2AB2	H2A.B Variant Histone 2	Protein Coding	1
32	H3C15	H3 Clustered Histone 15	Protein Coding	1
33	H2AZ1	H2A.Z Variant Histone 1	Protein Coding	1

Disorders associated with FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Bryant-li-bhoj neurodevelopmental syndrome 2	Enrichment	H3-3A, H3-3B	5.24
2	Weaver syndrome	Enrichment	EZH2, SUZ12	4.76
3	Glioma susceptibility 1	Enrichment	H3-3A, H3C1	3.80
4	Luo-schoch-yamamoto syndrome	Enrichment	RNF2	2.61
5	Noonan syndrome 13	Enrichment	MAPK1	2.61
6	Imagawa-matsumoto syndrome	Enrichment	SUZ12	2.61
7	Hypogonadotropic hypogonadism 19 with or without anosmia	Enrichment	DUSP6	2.61
8	Cohen-gibson syndrome	Enrichment	EED	2.61
9	Bryant-li-bhoj neurodevelopmental syndrome 1	Enrichment	H3-3A	2.61
10	Microphthalmia, syndromic 1	Enrichment	BCOR	2.31
11	Microphthalmia, syndromic 2	Enrichment	BCOR	2.31
12	Intravascular large b-cell lymphoma	Enrichment	BCL6	2.31
13	Brachydactyly-elbow wrist dysplasia syndrome	Enrichment	MACROH2A1	2.31
14	Primary mediastinal large b-cell lymphoma	Enrichment	BCL6	2.31
15	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL6	2.14
16	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	2.01
17	Follicular lymphoma	Enrichment	BCL6	1.92
18	Endometrial stromal sarcoma	Enrichment	SUZ12	1.92
19	Kidney clear cell sarcoma	Enrichment	BCOR	1.84
20	Specific learning disability	Enrichment	MAPK1	1.58
21	Acute promyelocytic leukemia	Enrichment	BCOR	1.51
22	Microcephaly	Enrichment	KDM2B, MAPK1	1.45
23	Heart, malformation of	Enrichment	MAPK1	1.37
24	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	DUSP6	1.37
25	Kallmann syndrome	Enrichment	DUSP6	1.26
26	Leukemia, acute myeloid	Enrichment	BCOR	1.03
27	West syndrome	Enrichment	KDM2B	0.99
28	Myeloma, multiple	Enrichment	H3C1	0.89
29	Autism spectrum disorder	Enrichment	EED	0.63
30	Complex neurodevelopmental disorder	Enrichment	RNF2	0.58
31	Inherited cancer-predisposing syndrome	Enrichment	EZH2	0.56

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma

Pathway Network for FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma

Member Pathways for FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma

Pathways in the FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma SuperPath

Associated Genes for FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma

Associated Disorders for FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma

Disorders associated with FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma SuperPath

STRING Interaction Network for FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma

Sources for FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma