Fc-GammaR Pathway

No Pathway Network information available for Fc-GammaR Pathway

Pathways in the Fc-GammaR Pathway SuperPath

#	Name	Source	Genes
1	Fc-GammaR Pathway	QIAGEN	BLNK BTK CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CDC42 DIRAS3 FCGR1A FCGR2A FCGR2B FCGR3B HCK HRAS ITPR1 ITPR2 ITPR3 KRAS LYN MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK8 MAPK9 MRAS NRAS PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLCG1 PLCG2 PRKCA PTK2B RAC1 RAC2 RAC3 RHOA RHOB RHOC RHOD RHOG RHOH RND2 RND3 RRAS RRAS2 SYK VAV1 VAV2 VAV3 (see all 76) (see less)
2	Fc-Gamma-RIIB Signaling in B-Cells	QIAGEN	AKT1 BLNK BTK CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CD79A CD79B DOK1 FCGR2B GRB2 HRAS KRAS LYN MAPK10 MAPK8 MAPK9 MRAS NRAS PDPK1 PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLCG2 RRAS RRAS2 SOS1 SOS2 SYK (see all 54) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	BLNK	B Cell Linker	Protein Coding	2
2	BTK	Bruton Tyrosine Kinase	Protein Coding	2
3	CACNA1A	Calcium Voltage-Gated Channel Subunit Alpha1 A	Protein Coding	2
4	CACNA1B	Calcium Voltage-Gated Channel Subunit Alpha1 B	Protein Coding	2
5	CACNA1C	Calcium Voltage-Gated Channel Subunit Alpha1 C	Protein Coding	2
6	CACNA1D	Calcium Voltage-Gated Channel Subunit Alpha1 D	Protein Coding	2
7	CACNA1E	Calcium Voltage-Gated Channel Subunit Alpha1 E	Protein Coding	2
8	CACNA1F	Calcium Voltage-Gated Channel Subunit Alpha1 F	Protein Coding	2
9	CACNA1G	Calcium Voltage-Gated Channel Subunit Alpha1 G	Protein Coding	2
10	CACNA1H	Calcium Voltage-Gated Channel Subunit Alpha1 H	Protein Coding	2
11	CACNA1I	Calcium Voltage-Gated Channel Subunit Alpha1 I	Protein Coding	2
12	CACNA1S	Calcium Voltage-Gated Channel Subunit Alpha1 S	Protein Coding	2
13	CACNA2D1	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 1	Protein Coding	2
14	CACNA2D2	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 2	Protein Coding	2
15	CACNA2D3	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 3	Protein Coding	2
16	CACNA2D4	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 4	Protein Coding	2
17	CACNB1	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 1	Protein Coding	2
18	CACNB2	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 2	Protein Coding	2
19	CACNB3	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 3	Protein Coding	2
20	CACNB4	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 4	Protein Coding	2
21	CACNG1	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 1	Protein Coding	2
22	CACNG2	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 2	Protein Coding	2
23	CACNG3	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 3	Protein Coding	2
24	CACNG4	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 4	Protein Coding	2
25	CACNG5	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 5	Protein Coding	2
26	CACNG6	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 6	Protein Coding	2
27	CACNG7	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 7	Protein Coding	2
28	CACNG8	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 8	Protein Coding	2
29	FCGR2B	Fc Gamma Receptor IIb	Protein Coding	2
30	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	2
31	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	2
32	LYN	LYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	2
33	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	2
34	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	2
35	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	2
36	MRAS	Muscle RAS Oncogene Homolog	Protein Coding	2
37	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	2
38	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	2
39	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	2
40	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	2
41	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	2
42	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	2
43	PLCG2	Phospholipase C Gamma 2	Protein Coding	2
44	RRAS	RAS Related	Protein Coding	2
45	RRAS2	RAS Related 2	Protein Coding	2
46	SYK	Spleen Associated Tyrosine Kinase	Protein Coding	2
47	RHOA	Ras Homolog Family Member A	Protein Coding	1
48	RHOB	Ras Homolog Family Member B	Protein Coding	1
49	RHOC	Ras Homolog Family Member C	Protein Coding	1
50	RHOD	Ras Homolog Family Member D	Protein Coding	1
51	RND3	Rho Family GTPase 3	Protein Coding	1
52	RHOG	Ras Homolog Family Member G	Protein Coding	1
53	RHOH	Ras Homolog Family Member H	Protein Coding	1
54	DIRAS3	DIRAS Family GTPase 3	Protein Coding	1
55	RND2	Rho Family GTPase 2	Protein Coding	1
56	CDC42	Cell Division Cycle 42	Protein Coding	1
57	FCGR1A	Fc Gamma Receptor Ia	Protein Coding	1
58	FCGR2A	Fc Gamma Receptor IIa	Protein Coding	1
59	FCGR3B	Fc Gamma Receptor IIIb	Protein Coding	1
60	HCK	HCK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
61	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
62	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	1
63	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	1
64	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	1
65	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	1
66	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	1
67	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
68	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
69	PRKCA	Protein Kinase C Alpha	Protein Coding	1
70	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	1
71	RAC1	Rac Family Small GTPase 1	Protein Coding	1
72	RAC2	Rac Family Small GTPase 2	Protein Coding	1
73	RAC3	Rac Family Small GTPase 3	Protein Coding	1
74	VAV1	Vav Guanine Nucleotide Exchange Factor 1	Protein Coding	1
75	VAV2	Vav Guanine Nucleotide Exchange Factor 2	Protein Coding	1
76	VAV3	Vav Guanine Nucleotide Exchange Factor 3	Protein Coding	1
77	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
78	CD79A	CD79a Molecule	Protein Coding	1
79	CD79B	CD79b Molecule	Protein Coding	1
80	DOK1	Docking Protein 1	Protein Coding	1
81	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	1
82	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	1
83	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	1
84	SOS2	SOS Ras/Rho Guanine Nucleotide Exchange Factor 2	Protein Coding	1

Disorders associated with Fc-GammaR Pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Rasopathy	Enrichment	HRAS, KRAS, MRAS, NRAS, RRAS2, SOS1, SOS2	16.00
2	Noonan syndrome 1	Enrichment	HRAS, KRAS, MRAS, NRAS, RRAS, RRAS2, SOS1, SOS2	10.74
3	Autosomal non-syndromic agammaglobulinemia	Enrichment	BLNK, CD79A, CD79B, PIK3R1	7.33
4	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	6.62
5	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, KRAS, NRAS, SOS1	6.53
6	Nevus, epidermal	Enrichment	HRAS, KRAS, NRAS	5.69
7	Noonan syndrome 3	Enrichment	HRAS, KRAS, SOS1	5.69
8	Lung non-small cell carcinoma	Enrichment	HRAS, KRAS, NRAS	5.02
9	Juvenile myelomonocytic leukemia	Enrichment	KRAS, NRAS, RRAS	4.89
10	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	4.81
11	Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures	Enrichment	CACNA1A, CACNA1C	4.33
12	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	4.33
13	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	4.03
14	Brugada syndrome	Enrichment	CACNA1C, CACNA2D1, CACNB2	3.84
15	Differentiated thyroid carcinoma	Enrichment	HRAS, KRAS, NRAS	3.69
16	Breast adenocarcinoma	Enrichment	AKT1, KRAS	3.64
17	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS, NRAS	3.49
18	Leukemia, chronic myeloid	Enrichment	KRAS, NRAS	3.49
19	Follicular thyroid carcinoma	Enrichment	HRAS, NRAS	3.49
20	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, NRAS	3.37
21	Lennox-gastaut syndrome	Enrichment	CACNA1A, MAPK10	3.37
22	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	CACNA1C, RAC1	2.96
23	Systemic lupus erythematosus	Enrichment	FCGR2A, FCGR2B, FCGR3B	2.87
24	Cone-rod dystrophy 6	Enrichment	CACNA1F, CACNA2D4	2.86
25	Undetermined early-onset epileptic encephalopathy	Enrichment	CACNA1A, CACNA1B, CACNA2D1	2.85
26	Diffuse large b-cell lymphoma	Enrichment	BTK, CD79B	2.59
27	Spastic ataxia	Enrichment	CACNA1G, CACNB4, ITPR1	2.49
28	Breast cancer	Enrichment	AKT1, CACNA2D1, KRAS	2.48
29	Congenital stationary night blindness	Enrichment	CACNA1F, CACNA2D4	2.43
30	Proteus syndrome	Enrichment	AKT1	2.40
31	Thyrotoxic periodic paralysis 1	Enrichment	CACNA1S	2.40
32	Oculoectodermal syndrome	Enrichment	KRAS	2.40
33	Noonan syndrome 4	Enrichment	SOS1	2.40
34	Epilepsy, idiopathic generalized 9	Enrichment	CACNB4	2.40
35	Brugada syndrome 4	Enrichment	CACNB2	2.40
36	Melanosis, neurocutaneous	Enrichment	NRAS	2.40
37	Noonan syndrome 9	Enrichment	SOS2	2.40
38	Noonan syndrome 6	Enrichment	NRAS	2.40
39	Episodic ataxia, type 5	Enrichment	CACNB4	2.40
40	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	2.40
41	Agammaglobulinemia 3, autosomal recessive	Enrichment	CD79A	2.40
42	Noonan syndrome 11	Enrichment	MRAS	2.40
43	Immunodeficiency 82 with systemic inflammation	Enrichment	SYK	2.40
44	Neurodevelopmental disorder with speech impairment and with or without seizures	Enrichment	CACNA1I	2.40
45	Congenital myopathy 18	Enrichment	CACNA1S	2.40
46	Short syndrome	Enrichment	PIK3R1	2.40
47	Cone-rod dystrophy, x-linked, 3	Enrichment	CACNA1F	2.40
48	Isolated growth hormone deficiency type iii	Enrichment	BTK	2.40
49	Retinal cone dystrophy 4	Enrichment	CACNA2D4	2.40
50	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	2.40
51	Primary aldosteronism, seizures, and neurologic abnormalities	Enrichment	CACNA1D	2.40
52	Brugada syndrome 3	Enrichment	CACNA1C	2.40
53	Epilepsy, childhood absence 6	Enrichment	CACNA1H	2.40
54	Malignant hyperthermia 5	Enrichment	CACNA1S	2.40
55	Intellectual developmental disorder, autosomal dominant 10	Enrichment	CACNG2	2.40
56	Sinoatrial node dysfunction and deafness	Enrichment	CACNA1D	2.40
57	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.40
58	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	2.40
59	Cowden syndrome 6	Enrichment	AKT1	2.40
60	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.40
61	Spinocerebellar ataxia 42	Enrichment	CACNA1G	2.40
62	Developmental and epileptic encephalopathy 110	Enrichment	CACNA2D1	2.40
63	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	2.40
64	Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits	Enrichment	CACNA1G	2.40
65	Developmental and epileptic encephalopathy 69	Enrichment	CACNA1E	2.40
66	Hyperaldosteronism, familial, type iv	Enrichment	CACNA1H	2.40
67	Autoinflammatory disease, systemic, with vasculitis	Enrichment	LYN	2.40
68	Colitis	Enrichment	SYK	2.40
69	Conn's syndrome	Enrichment	CACNA1H	2.40
70	Congenital pulmonary airway malformation	Enrichment	KRAS	2.40
71	Agammaglobulinemia 3	Enrichment	CD79A	2.40
72	Sporadic hemiplegic migraine	Enrichment	CACNA1A	2.40
73	Atypical timothy syndrome	Enrichment	CACNA1C	2.40
74	Aldosterone-producing adenoma with seizures and neurological abnormalities	Enrichment	CACNA1D	2.40
75	Timothy syndrome type 2	Enrichment	CACNA1C	2.40
76	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.40
77	Periodic paralysis with transient compartment-like syndrome	Enrichment	CACNA1S	2.40
78	Timothy syndrome type 1	Enrichment	CACNA1C	2.40
79	Neurocutaneous melanocytosis	Enrichment	NRAS	2.40
80	Cacna1c-related disorders	Enrichment	CACNA1C	2.40
81	Benign paroxysmal torticollis of infancy	Enrichment	CACNA1A	2.40
82	Colorectal cancer	Enrichment	AKT1, NRAS, PIK3R1	2.30
83	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	2.25
84	Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	Enrichment	RAC2	2.25
85	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	2.25
86	Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies	Enrichment	RAC3	2.25
87	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.25
88	Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia	Enrichment	RAC2	2.25
89	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.25
90	Takenouchi-kosaki syndrome	Enrichment	CDC42	2.25
91	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.25
92	Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia	Enrichment	RAC2	2.25
93	Immunodeficiency 129	Enrichment	RHOH	2.25
94	Autoinflammation with pulmonary and cutaneous vasculitis	Enrichment	HCK	2.25
95	T-cell immunodeficiency with epidermodysplasia verruciformis	Enrichment	RHOH	2.25
96	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	2.25
97	Neonatal alloimmune neutropenia	Enrichment	FCGR3B	2.25
98	Infantile lad-like disease due to rac2 deficiency	Enrichment	RAC2	2.25
99	Reticular dysgenesis-like severe combined immunodeficiency	Enrichment	RAC2	2.25
100	Nocarh syndrome	Enrichment	CDC42	2.25
101	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.25
102	Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome	Enrichment	RAC2	2.25
103	Bladder cancer	Enrichment	HRAS, KRAS	2.23
104	Long qt syndrome	Enrichment	CACNA1C, CACNA1S	2.17
105	Non-immune hydrops fetalis	Enrichment	HRAS, KRAS	2.17
106	Malaria	Enrichment	FCGR2A, FCGR2B	2.14
107	Ovarian cancer	Enrichment	AKT1, KRAS, RRAS2	2.12
108	Fibromatosis, gingival, 1	Enrichment	SOS1	2.10
109	Costello syndrome	Enrichment	HRAS	2.10
110	Timothy syndrome	Enrichment	CACNA1C	2.10
111	Night blindness, congenital stationary, type 2a	Enrichment	CACNA1F	2.10
112	Pulmonic stenosis	Enrichment	SOS1	2.10
113	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	2.10
114	Isolated growth hormone deficiency, type iii, with agammaglobulinemia	Enrichment	BTK	2.10
115	Alternating hemiplegia of childhood 1	Enrichment	CACNA1A	2.10
116	Agammaglobulinemia 4, autosomal recessive	Enrichment	BLNK	2.10
117	Agammaglobulinemia 6, autosomal recessive	Enrichment	CD79B	2.10
118	Encephalocraniocutaneous lipomatosis	Enrichment	KRAS	2.10
119	Long qt syndrome 8	Enrichment	CACNA1C	2.10
120	Myopia 28, autosomal recessive	Enrichment	DOK1	2.10
121	Agammaglobulinemia, x-linked	Enrichment	BTK	2.10
122	Noonan syndrome 12	Enrichment	RRAS2	2.10
123	Agammaglobulinemia 4	Enrichment	BLNK	2.10
124	Agammaglobulinemia 6	Enrichment	CD79B	2.10
125	Congenital disorder of glycosylation, type iw, autosomal dominant	Enrichment	CACNA1D	2.10
126	Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements	Enrichment	CACNA1B	2.10
127	Arthritis	Enrichment	SYK	2.10
128	Progressive bulbar palsy	Enrichment	CACNA1A	2.10
129	Wooly hair nevus	Enrichment	HRAS	2.10
130	Eye disease	Enrichment	CACNA1F, CACNA2D4	2.07
131	Developmental and epileptic encephalopathy	Enrichment	CACNA1E, CACNA2D2	2.05
132	Cerebral palsy	Enrichment	CACNA1A, CACNA1C	1.98
133	Leukemia, acute myeloid	Enrichment	KRAS, NRAS	1.96
134	Spinocerebellar ataxia 29	Enrichment	ITPR1	1.95
135	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	1.95
136	Immune system disease	Enrichment	CDC42	1.95
137	Van der woude syndrome 1	Enrichment	CACNA1E	1.92
138	Agammaglobulinemia 1, autosomal recessive	Enrichment	BTK	1.92
139	Nuchal bleb, familial	Enrichment	SOS1	1.92
140	Langerhans cell histiocytosis	Enrichment	NRAS	1.92
141	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3R1	1.92
142	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	1.92
143	Agammaglobulinemia 1	Enrichment	BTK	1.92
144	Immunodeficiency 14	Enrichment	PIK3R1	1.92
145	Spermatocytoma	Enrichment	HRAS	1.92
146	Thyrotoxic periodic paralysis	Enrichment	CACNA1S	1.92
147	Hereditary episodic ataxia	Enrichment	CACNA1A	1.92
148	Long qt syndrome 1	Enrichment	CACNA1C, ITPR3	1.91
149	Hereditary breast carcinoma	Enrichment	AKT1, KRAS	1.88
150	Migraine, familial hemiplegic, 1	Enrichment	CACNA1A	1.80
151	Cardiofaciocutaneous syndrome 1	Enrichment	KRAS	1.80
152	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	1.80
153	Spinocerebellar ataxia 6	Enrichment	CACNA1A	1.80
154	Aland island eye disease	Enrichment	CACNA1F	1.80
155	Developmental and epileptic encephalopathy 2	Enrichment	CACNA1A	1.80
156	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3R2	1.80
157	Ventricular fibrillation, paroxysmal familial, 1	Enrichment	CACNA1C	1.80
158	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	1.80
159	Developmental and epileptic encephalopathy 42	Enrichment	CACNA1A	1.80
160	Cerebellar atrophy with seizures and variable developmental delay	Enrichment	CACNA2D2	1.80
161	Developmental and epileptic encephalopathy 52	Enrichment	CACNA1A	1.80
162	Cardiofaciocutaneous syndrome	Enrichment	KRAS	1.80
163	Lung sarcomatoid carcinoma	Enrichment	KRAS	1.80
164	Pilocytic astrocytoma	Enrichment	KRAS	1.80
165	Epidermolytic nevus	Enrichment	HRAS	1.80
166	Malignant hyperthermia	Enrichment	CACNA1S	1.80
167	Episodic ataxia	Enrichment	CACNA1A	1.80
168	Familial or sporadic hemiplegic migraine	Enrichment	CACNA1A	1.80
169	Gingival fibromatosis	Enrichment	SOS1	1.80
170	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	SOS2	1.80
171	Gillespie syndrome	Enrichment	ITPR1	1.78
172	Autosomal dominant non-syndromic intellectual disability	Enrichment	CACNA1I, CACNG2	1.77
173	Episodic ataxia, type 2	Enrichment	CACNA1A	1.70
174	Heart conduction disease	Enrichment	CACNA1C	1.70
175	Amblyopia	Enrichment	CACNA1F	1.70
176	Cardiac arrest	Enrichment	CACNA2D1	1.70
177	Congenital short qt syndrome	Enrichment	CACNA2D1	1.70
178	Myeloma, multiple	Enrichment	KRAS, PIK3R2	1.68
179	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.65
180	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CDC42	1.65
181	Hypokalemic periodic paralysis, type 1	Enrichment	CACNA1S	1.63
182	Lung squamous cell carcinoma	Enrichment	KRAS	1.63
183	Childhood absence epilepsy	Enrichment	CACNA1H	1.63
184	Brugada syndrome 1	Enrichment	CACNA2D1	1.56
185	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS	1.56
186	Gallbladder cancer	Enrichment	KRAS	1.56
187	Pilomyxoid astrocytoma	Enrichment	KRAS	1.56
188	Overgrowth syndrome	Enrichment	PIK3R1	1.56
189	Cone-rod dystrophy 2	Enrichment	CACNA1F, CACNA2D4	1.52
190	Alternating hemiplegia of childhood	Enrichment	CACNA1A	1.50
191	Difference of sex development	Enrichment	CACNA1A	1.50
192	Hemihyperplasia, isolated	Enrichment	RHOA	1.48
193	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	1.48
194	Arteriovenous malformation	Enrichment	HRAS	1.45
195	Primary hyperaldosteronism	Enrichment	CACNA1H	1.45
196	Cowden syndrome	Enrichment	AKT1	1.45
197	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS	1.41
198	Migraine with or without aura 1	Enrichment	CACNA1A	1.37
199	Epilepsy, myoclonic juvenile	Enrichment	CACNB4	1.37
200	Immune deficiency disease	Enrichment	SYK	1.37
201	Epilepsy, idiopathic generalized	Enrichment	CACNA1H	1.37
202	Cardiac conduction defect	Enrichment	CACNA1C	1.33
203	Meningioma	Enrichment	AKT1	1.33
204	Lip and oral cavity carcinoma	Enrichment	HRAS	1.33
205	Aortic valve disease 1	Enrichment	SOS1	1.30
206	Protein-deficiency anemia	Enrichment	NRAS	1.30
207	Lung cancer susceptibility 3	Enrichment	KRAS	1.26
208	46,xy partial gonadal dysgenesis	Enrichment	SOS1	1.26
209	Myopia	Enrichment	CACNA1F	1.24
210	Lynch syndrome	Enrichment	KRAS	1.24
211	Rhabdomyosarcoma	Enrichment	HRAS	1.21
212	Congenital long qt syndrome	Enrichment	ITPR3	1.19
213	Arteriovenous malformations of the brain	Enrichment	KRAS	1.14
214	Congenital myopathy	Enrichment	CACNA1S	1.14
215	Multiple sclerosis	Enrichment	ITPR1	1.12
216	Centronuclear myopathy	Enrichment	CACNA1S	1.09
217	Anterior segment dysgenesis	Enrichment	ITPR1	1.09
218	Cardiomyopathy, familial hypertrophic, 1	Enrichment	CACNA1C	1.04
219	Cone dystrophy	Enrichment	CACNA2D4	1.04
220	Pancreatic cancer	Enrichment	KRAS	1.02
221	Hydrops fetalis, nonimmune	Enrichment	HRAS	1.01
222	Auditory neuropathy	Enrichment	CACNA1A	1.01
223	Strabismus	Enrichment	CACNA1A	0.99
224	Lung cancer	Enrichment	KRAS	0.92
225	Complex neurodevelopmental disorder	Enrichment	CACNA1C, RAC3	0.81
226	Gastric cancer	Enrichment	KRAS	0.80
227	Optic atrophy plus syndrome	Enrichment	CACNA1F	0.79
228	Cystic fibrosis	Enrichment	FCGR2A	0.78
229	Hereditary breast ovarian cancer syndrome	Enrichment	KRAS	0.70
230	Retinitis pigmentosa	Enrichment	CACNA1F, CACNA2D4	0.69
231	Hereditary retinal dystrophy	Enrichment	CACNA1F, CACNA2D4	0.49
232	Fundus dystrophy	Enrichment	CACNA1F, CACNA2D4	0.49
233	Congenital nervous system abnormality	Enrichment	CACNA1A	0.46
234	Nervous system disease	Enrichment	CACNA1A	0.46

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Fc-GammaR Pathway

Pathway Network for Fc-GammaR Pathway

Member Pathways for Fc-GammaR Pathway

Pathways in the Fc-GammaR Pathway SuperPath

Associated Genes for Fc-GammaR Pathway

Associated Disorders for Fc-GammaR Pathway

Disorders associated with Fc-GammaR Pathway SuperPath

STRING Interaction Network for Fc-GammaR Pathway

Sources for Fc-GammaR Pathway