Fentanyl Pathway, Pharmacokinetics/Pharmacodynamics
Pathways in the Fentanyl Pathway, Pharmacokinetics/Pharmacodynamics SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Fentanyl Pathway, Pharmacokinetics/Pharmacodynamics | PharmGKB |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | CYP3A4 | Cytochrome P450 Family 3 Subfamily A Member 4 | Protein Coding | 1 |
| 2 | CYP3A5 | Cytochrome P450 Family 3 Subfamily A Member 5 | Protein Coding | 1 |
| 3 | OPRD1 | Opioid Receptor Delta 1 | Protein Coding | 1 |
| 4 | OPRK1 | Opioid Receptor Kappa 1 | Protein Coding | 1 |
| 5 | OPRM1 | Opioid Receptor Mu 1 | Protein Coding | 1 |
Disorders associated with Fentanyl Pathway, Pharmacokinetics/Pharmacodynamics SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Vitamin d-dependent rickets, type 3 | Enrichment | CYP3A4 | 3.43 |
| 2 | Hypertension, essential | Enrichment | CYP3A5 | 2.20 |
