Formation of HIV elongation complex in the absence of HIV Tat

Pathway network for the Formation of HIV elongation complex in the absence of HIV Tat SuperPath

Sources:
  • Reactome
  • WikiPathways

Pathways in the Formation of HIV elongation complex in the absence of HIV Tat SuperPath

#NameSourceGenes
1Formation of HIV elongation complex in the absence of HIV TatReactome
2RNA Polymerase II Pre-transcription EventsReactome
3RNA polymerase II transcribes snRNA genesReactome
4Transcription of the HIV genomeReactome
5TP53 Regulates Transcription of DNA Repair GenesReactome
6Formation of RNA Pol II elongation complexReactome
7RNA Polymerase II Transcription ElongationReactome
8HIV Transcription ElongationReactome
9Tat-mediated elongation of the HIV-1 transcriptReactome
10Formation of HIV-1 elongation complex containing HIV-1 TatReactome
11Pausing and recovery of HIV elongationReactome
12Formation of the HIV-1 Early Elongation ComplexReactome
13HIV elongation arrest and recoveryReactome
14Formation of the Early Elongation ComplexReactome
15Pausing and recovery of Tat-mediated HIV elongationReactome
16Tat-mediated HIV elongation arrest and recoveryReactome
17mRNA CappingReactome
18PIWI-interacting RNA (piRNA) biogenesisReactome
19RNA Pol II CTD phosphorylation and interaction with CEReactome
20RNA Pol II CTD phosphorylation and interaction with CE during HIV infectionReactome
21FGFR2 alternative splicingReactome
22MicroRNA (miRNA) biogenesisReactome
23Abortive elongation of HIV-1 transcript in the absence of TatReactome
24miRNA biogenesisWikiPathways
25Interactions of Tat with host cellular proteinsReactome

Gene overlap in member pathways for Formation of HIV elongation complex in the absence of HIV Tat SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

Disorders associated with Formation of HIV elongation complex in the absence of HIV Tat SuperPath

according to GeneCards Suite gene sharing
#DisorderTypeGenesScore
1Human immunodeficiency virus infectious diseaseDirect
2Male infertilityEnrichmentFKBP6, MAEL, MOV10L1, PIWIL1, PLD6, TDRD1, TDRD12, TDRD916.00
3Gastric cancerEnrichmentATM, BRCA1, FANCI, MLH1, MSH2, PMS2, RAD51D, TP5310.56
4Ovarian cancerEnrichmentATM, BRCA1, ERCC2, ERCC3, FANCC, FANCD2, MSH2, PMS2, RAD51D, TP5310.52
5Breast cancerEnrichmentATM, BRCA1, FANCC, JUN, MLH1, MSH2, PMS2, RAD51D, TP5310.20
6Colorectal cancerEnrichmentATM, BRCA1, FANCC, FANCI, MLH1, MSH2, PMS2, RAD51D, TP539.68
7Lynch syndrome 1EnrichmentATM, MLH1, MSH2, PMS2, RAD51D9.39
8Hereditary breast ovarian cancer syndromeEnrichmentATM, BRCA1, MLH1, MSH2, PMS2, RAD51D, TP538.30
9Inherited cancer-predisposing syndromeEnrichmentATM, BRCA1, ERCC3, FANCC, MLH1, MSH2, PMS2, RAD51D, TP538.11
10Endometrial cancerEnrichmentATM, BRCA1, MLH1, MSH2, PMS27.49
11Hereditary breast carcinomaEnrichmentATM, BRCA1, MLH1, MSH2, RAD51D, TP537.36
12AzoospermiaEnrichmentHENMT1, MOV10L1, TDRD9, TDRKH7.10
13TrichothiodystrophyEnrichmentERCC2, ERCC3, GTF2E2, GTF2H56.84
14PineoblastomaEnrichmentDICER1, DROSHA6.79
15Breast-ovarian cancer, familial 1EnrichmentATM, BRCA1, MSH2, RAD51D6.56
16Mismatch repair cancer syndrome 1EnrichmentMLH1, MSH2, PMS26.44
17RhabdomyosarcomaEnrichmentBRCA1, MSH2, PMS2, TP536.16
18Bladder cancerEnrichmentATM, BRCA1, ERCC2, TP535.06
19Prostate cancerEnrichmentATM, BRCA1, RAD51D, TP535.06
20Familial colorectal cancerEnrichmentMLH1, MSH2, TP534.97
21Xeroderma pigmentosum, variant typeEnrichmentDDB2, ERCC2, ERCC34.84
22Uterine corpus cancerEnrichmentATM, BRCA1, MSH24.84
23Fanconi anemia, complementation group aEnrichmentBRCA1, FANCC, FANCD2, FANCI4.73
24Muir-torre syndromeEnrichmentMLH1, MSH24.69
25Xeroderma pigmentosum-cockayne syndrome complexEnrichmentERCC2, ERCC34.42
26Lynch syndromeEnrichmentMLH1, MSH2, PMS24.40
27GliosarcomaEnrichmentATM, MSH2, TP534.31
28Giant cell glioblastomaEnrichmentATM, MSH2, TP534.23
29AdenocarcinomaEnrichmentATM, TP534.21
30HepatoblastomaEnrichmentERCC2, MSH2, TP533.94
31Lynch syndrome 4EnrichmentMSH2, PMS23.91
32Pancreatic cancerEnrichmentATM, BRCA1, TP533.71
33Breast-ovarian cancer, familial 2EnrichmentBRCA1, PMS23.69
34LymphomaEnrichmentPMS2, TP533.69
35GlioblastomaEnrichmentATM, MSH23.69
36Male infertility with azoospermia or oligozoospermia due to single gene mutationEnrichmentASZ1, MOV10L1, TDRD93.65
37Rhabdomyosarcoma, embryonal, 2EnrichmentDICER13.35
38Dicer1 syndromeEnrichmentDICER13.35
39Pleuropulmonary blastomaEnrichmentDICER13.35
40Global developmental delay, lung cysts, overgrowth, and wilms tumorEnrichmentDICER13.35
41Malignant sertoli-leydig cell tumor of ovaryEnrichmentDICER13.35
42Supratentorial primitive neuroectodermal tumorEnrichmentDICER13.35
43GynandroblastomaEnrichmentDICER13.35
44Dicer1 tumor predispositionEnrichmentDICER13.35
45Colonic benign neoplasmEnrichmentATM, MLH13.14
46Goiter, multinodular 1, with or without sertoli-leydig cell tumorsEnrichmentDICER13.05
47Vertebral anomalies and variable endocrine and t-cell dysfunctionEnrichmentDICER13.05
48Malignant granulosa cell tumor of the ovaryEnrichmentDICER13.05
49Leukemia, chronic lymphocyticEnrichmentATM, TP533.04
50Embryonal rhabdomyosarcomaEnrichmentDICER12.75
51Lung cancer susceptibility 3EnrichmentCDK12, TP532.74
52Inclusion body myopathy with early-onset paget disease with or without frontotemporal dementia 3EnrichmentHNRNPA12.72
53Myopathy, distal, 3EnrichmentHNRNPA12.72
54Amyotrophic lateral sclerosis 20EnrichmentHNRNPA12.72
55Finnish upper limb-onset distal myopathyEnrichmentHNRNPA12.72
56Amyotrophic lateral sclerosis 26 with or without frontotemporal dementiaEnrichmentTIA12.72
57Relapsing-remitting multiple sclerosisEnrichmentHNRNPA12.72
58Xeroderma pigmentosum, complementation group bEnrichmentERCC32.70
59Xeroderma pigmentosum, complementation group dEnrichmentERCC22.70
60Trichothiodystrophy 2, photosensitiveEnrichmentERCC32.70
61Xeroderma pigmentosum group bEnrichmentERCC32.70
62Cerebrooculofacioskeletal syndrome 2EnrichmentERCC22.70
63Trichothiodystrophy 3, photosensitiveEnrichmentGTF2H52.70
64Xeroderma pigmentosum group dEnrichmentERCC22.70
65Spermatogenic failure 73EnrichmentMOV10L12.67
66Spermatogenic failure 77EnrichmentFKBP62.67
67Spermatogenic failure 30EnrichmentTDRD92.67
68Diffuse large b-cell lymphomaEnrichmentPMS2, TP532.48
69Waardenburg syndrome, type 4cEnrichmentPOLR2F2.45
70Premature ovarian failure 3EnrichmentAGO22.45
71Dystonia 16EnrichmentPRKRA2.45
72Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizuresEnrichmentAGO12.45
73Peripheral demyelinating neuropathy, central dysmyelination, waardenburg syndrome, and hirschsprung diseaseEnrichmentPOLR2F2.45
74Welander distal myopathyEnrichmentTIA12.42
75Deafness, autosomal recessive 109EnrichmentESRP12.42
76Neurodevelopmental disorder with craniofacial dysmorphism and skeletal defectsEnrichmentHNRNPH12.42
77Parathyroid carcinomaEnrichmentCDC732.37
78Hyperparathyroidism 2 with jaw tumorsEnrichmentCDC732.37
79Chops syndromeEnrichmentAFF42.37
80Cdc73-related disordersEnrichmentCDC732.37
81Intellectual developmental disorder with hypertelorism and distinctive faciesEnrichmentCCNK2.37
82Neurodevelopmental disorder with dysmorphic facies and thin corpus callosumEnrichmentSUPT16H2.37
83Hepatocellular carcinomaEnrichmentPMS2, TP532.35
84Palmoplantar keratoderma, punctate type iiEnrichmentBRCA12.34
85Seckel syndrome 1EnrichmentATR2.34
86Bone marrow failure syndrome 5EnrichmentTP532.34
87Papilloma of choroid plexusEnrichmentTP532.34
88Basal cell carcinoma 7EnrichmentTP532.34
89Lynch syndrome 2EnrichmentMLH12.34
90Anaplastic thyroid carcinomaEnrichmentTP532.34
91Infant-type hemispheric gliomaEnrichmentBRCA12.34
92Cutaneous telangiectasia and cancer syndrome, familialEnrichmentATR2.34
93Endometrial serous adenocarcinomaEnrichmentATM2.34
94Ductal carcinoma in situEnrichmentTP532.34
95Mismatch repair cancer syndrome 2EnrichmentMSH22.34
96Mismatch repair cancer syndrome 4EnrichmentPMS22.34
97Rectal benign neoplasmEnrichmentMSH22.34
98Thyroid gland undifferentiated carcinomaEnrichmentTP532.34
99Small-cell carcinoma of the ovary of hypercalcemic typeEnrichmentTP532.34
100Pituitary cancerEnrichmentPMS22.34
101Ascending colon cancerEnrichmentMSH22.34
102Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtypeEnrichmentTP532.34
103Oocyte/zygote/embryo maturation arrest 21EnrichmentCHEK12.34
104B-cell non-hodgkin lymphomaEnrichmentATM2.34
105Choroid plexus cancerEnrichmentTP532.34
106Ovarian cystEnrichmentMSH22.34
107Pleomorphic xanthoastrocytomaEnrichmentTP532.34
108Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndromeEnrichmentATR2.34
109Primary peritoneal carcinomaEnrichmentBRCA12.34
110Congenital cataracts, facial dysmorphism, and neuropathyEnrichmentCTDP12.31
111Waardenburg syndrome, type 2aEnrichmentPOLR2F2.28
112Lessel-kreienkamp syndromeEnrichmentAGO22.28
113Trichothiodystrophy 6, nonphotosensitiveEnrichmentGTF2E22.26
114Neurodevelopmental disorder with severe motor impairment, absent language, cerebral hypomyelination, and brain atrophyEnrichmentTAF82.26
115Neurodevelopmental disorder with cerebellar hypoplasia and spasticityEnrichmentINTS82.26
116Alazami-yuan syndromeEnrichmentTAF62.26
117Intellectual developmental disorder, autosomal recessive 60EnrichmentTAF132.26
118Neurodevelopmental disorder with motor regression, progressive spastic paraplegia, and oromotor dysfunctionEnrichmentSNAPC42.26
119Neurodevelopmental disorder with motor and language delay, ocular defects, and brain abnormalitiesEnrichmentINTS112.26
120Distal myopathyEnrichmentHNRNPA12.24
121Inclusion body myopathy with paget disease of bone and frontotemporal dementiaEnrichmentHNRNPA12.24
122Trichothiodystrophy 1, photosensitiveEnrichmentERCC22.22
123Wieacker-wolff syndromeEnrichmentCCNH2.22
124Intellectual developmental disorder, x-linked, syndromic 33EnrichmentTAF12.22
125Dystonia 3, torsion, x-linkedEnrichmentTAF12.22
126Neurodevelopmental disorder with feeding difficulties, thin corpus callosum, and foot deformityEnrichmentTAF22.22
127Spermatogenic failure 13EnrichmentTAF4B2.22
128X-linked intellectual disability-global development delay-facial dysmorphism-sacral caudal remnant syndromeEnrichmentTAF12.22
129Adenoid cystic carcinomaEnrichmentMYBL12.19
130Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalitiesEnrichmentPOLR2A2.15
131Intellectual developmental disorder, x-linked, syndromic, bain typeEnrichmentHNRNPH12.12
132Intellectual disability, x-linked, syndromic, bain typeEnrichmentHNRNPH12.12
133CraniopharyngiomaEnrichmentERCC22.10
134Charcot-marie-tooth hereditary neuropathyEnrichmentTDRKH2.07
135Hyperparathyroidism 1EnrichmentCDC732.07
13614q11.2 microduplication syndromeEnrichmentSUPT16H2.07
137Acute myeloid leukemia with t(9;11)(p22;q23)EnrichmentMLLT32.07
138Hypogonadotropic hypogonadism 1 with or without anosmiaEnrichmentPOLR2F2.05
139Burkitt lymphomaEnrichmentPMS22.04
140Adrenocortical carcinoma, hereditaryEnrichmentTP532.04
141Cervical cancerEnrichmentTP532.04
142Xeroderma pigmentosum, complementation group eEnrichmentDDB22.04
143Fanconi anemia, complementation group iEnrichmentFANCI2.04
144Lymphoma, hodgkin, classicEnrichmentTP532.04
145Congenital heart defects, dysmorphic facial features, and intellectual developmental disorderEnrichmentCDK132.04
146Fanconi anemia, complementation group sEnrichmentBRCA12.04
147Cardiac valvular dysplasia, x-linkedEnrichmentATM2.04
148Pancreatic cancer 4EnrichmentBRCA12.04
149Congenital fibrosarcomaEnrichmentTP532.04
150High grade gliomaEnrichmentATM2.04
151Li-fraumeni syndrome 1EnrichmentTP532.04
152SarcomaEnrichmentTP532.04
153Cervix carcinomaEnrichmentTP532.04
154Hodgkin's lymphomaEnrichmentTP532.04
155T-cell prolymphocytic leukemiaEnrichmentATM2.04
156Inflammatory breast carcinomaEnrichmentBRCA12.04
157Peritoneum cancerEnrichmentBRCA12.04
158Bilateral breast cancerEnrichmentBRCA12.04
159Xeroderma pigmentosum group eEnrichmentDDB22.04
160Pleomorphic rhabdomyosarcomaEnrichmentTP532.04
161Lung cancerEnrichmentBRCA1, MLH12.03
162Capillary malformations, congenitalEnrichmentCCNH2.00
163Waardenburg syndrome, type 4aEnrichmentPOLR2F1.98
164Waardenburg syndromeEnrichmentPOLR2F1.98
165Spinocerebellar ataxia 17EnrichmentTBP1.96
166Neurodevelopmental disorder with cataracts, poor growth, and dysmorphic faciesEnrichmentINTS11.96
167Cleft lip with or without cleft palateEnrichmentESRP21.94
168Klippel-trenaunay-weber syndromeEnrichmentCCNH1.92
169Cerebrooculofacioskeletal syndrome 1EnrichmentERCC21.92
170Telangiectasia, hereditary hemorrhagic, type 1EnrichmentCCNH1.92
171Hemangioma, capillary infantileEnrichmentCCNH1.92
172Basal cell carcinoma 1EnrichmentCCNH1.92
173Intellectual developmental disorder, autosomal dominant 73EnrichmentTAF41.92
174Waardenburg syndrome, type 1EnrichmentPOLR2F1.91
175Waardenburg syndrome, type 2eEnrichmentPOLR2F1.91
176Parathyroid adenomaEnrichmentCDC731.89
177Familial isolated hyperparathyroidismEnrichmentCDC731.89
178Ataxia-telangiectasiaEnrichmentATM1.86
179Polycythemia veraEnrichmentATM1.86
180Osteogenic sarcomaEnrichmentTP531.86
181Nasopharyngeal carcinomaEnrichmentTP531.86
182Breast-ovarian cancer, familial 4EnrichmentRAD51D1.86
183Koolen-de vries syndromeEnrichmentATM1.86
184Atypical teratoid rhabdoid tumorEnrichmentTP531.86
185Anaplastic astrocytomaEnrichmentTP531.86
186Squamous cell carcinomaEnrichmentTP531.86
187Cellular ependymomaEnrichmentMSH21.86
188Tanycytic ependymomaEnrichmentMSH21.86
189Papillary ependymomaEnrichmentMSH21.86
190Hereditary site-specific ovarian cancer syndromeEnrichmentRAD51D1.86
191Bone osteosarcomaEnrichmentTP531.86
192Clear cell ependymomaEnrichmentMSH21.86
193Capillary malformation-arteriovenous malformation 1EnrichmentCCNH1.86
194Hereditary hemorrhagic telangiectasiaEnrichmentCCNH1.86
195Leukemia, acute myeloidEnrichmentFANCD2, TP531.84
196Wolf-hirschhorn syndromeEnrichmentNELFA1.84
197Inflammatory bowel disease 1EnrichmentERCC21.75
198Arteriovenous malformationEnrichmentCCNH1.75
199Hypotrichosis simplexEnrichmentERCC21.75
200Small cell cancer of the lungEnrichmentTP531.74
201Erythrocytosis, familial, 2EnrichmentFANCD21.74
202Thyroid cancer, nonmedullary, 1EnrichmentTP531.74
203Polyposis syndrome, hereditary mixed, 1EnrichmentBRCA11.74
204CholangiocarcinomaEnrichmentBRCA11.74
205Congenital generalized lipodystrophyEnrichmentFOS1.74
206Mantle cell lymphomaEnrichmentATM1.74
207Lung sarcomatoid carcinomaEnrichmentTP531.74
208Benign ependymomaEnrichmentMSH21.74
209Oculomotor apraxiaEnrichmentATM1.74
210Male infertility due to gonadal dysgenesis or sperm disorderEnrichmentCHEK11.74
211Myopathy, x-linked, with excessive autophagyEnrichmentCCNH1.70
212Complex neurodevelopmental disorderEnrichmentAGO1, AGO21.70
213Fanconi anemia, complementation group d2EnrichmentFANCD21.64
214Von hippel-lindau syndromeEnrichmentFANCD21.64
215Rhabdomyosarcoma 2EnrichmentTP531.64
216Histiocytoid hemangiomaEnrichmentFOS1.64
217Acute megakaryocytic leukemiaEnrichmentTP531.64
218Myeloma, multipleEnrichmentATM, TP531.57
219Li-fraumeni syndromeEnrichmentTP531.57
220Adrenocortical carcinomaEnrichmentTP531.57
221Clear cell renal cell carcinomaEnrichmentATM1.57
222Breast adenocarcinomaEnrichmentTP531.57
223Corpus callosum, agenesis ofEnrichmentERCC21.53
224Isolated corpus callosum agenesisEnrichmentERCC21.53
225Intellectual disability-hypoplastic corpus callosum-preauricular tag syndromeEnrichmentERCC21.53
226Chondrosarcoma, extraskeletal myxoidEnrichmentTAF151.53
227Multiple endocrine neoplasia, type iEnrichmentCDC731.53
228Esophageal cancerEnrichmentTP531.50
229Mitochondrial dna depletion syndrome 4aEnrichmentFANCI1.50
230Squamous cell carcinoma, head and neckEnrichmentTP531.50
231Renal cell carcinoma, papillary, 1EnrichmentATM1.50
232Essential thrombocythemiaEnrichmentTP531.50
233Gallbladder cancerEnrichmentTP531.50
234B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)EnrichmentTP531.50
235Esophageal atresia/tracheoesophageal fistulaEnrichmentPOLR2B1.48
236Glioma susceptibility 1EnrichmentTP531.44
237Fanconi anemia, complementation group cEnrichmentFANCC1.44
238Lymphoma, non-hodgkin, familialEnrichmentTP531.44
239LeukodystrophyEnrichmentERCC21.41
240Kallmann syndromeEnrichmentPOLR2F1.40
241Adult hepatocellular carcinomaEnrichmentTP531.39
242Primary hyperaldosteronismEnrichmentTP531.39
243Williams-beuren syndromeEnrichmentFKBP61.38
244Cornelia de lange syndrome 1EnrichmentTAF61.32
245Cornelia de lange syndromeEnrichmentTAF61.32
246Immune deficiency diseaseEnrichmentATM1.31
247Myelodysplastic syndromeEnrichmentTP531.31
248Cardiomyopathy, familial hypertrophic, 9EnrichmentPMS21.31
249Familial colorectal cancer type xEnrichmentATM1.31
250Hirschsprung disease 1EnrichmentPOLR2F1.30
251Lip and oral cavity carcinomaEnrichmentTP531.27
252Periventricular nodular heterotopiaEnrichmentBRCA11.21
253Seckel syndromeEnrichmentATR1.21
254Wilms tumor 1EnrichmentCTR91.21
255Renal cell carcinoma, nonpapillaryEnrichmentATM1.18
256Acute promyelocytic leukemiaEnrichmentNABP11.16
257Heart, malformation ofEnrichmentCDK131.10
258Syndromic intellectual disabilityEnrichmentTAF61.05
259Charcot-marie-tooth diseaseEnrichmentCTDP11.02
260Cardiomyopathy, dilated, 1gEnrichmentPMS21.02
261Parkinson's diseaseEnrichmentTBP1.01
262Diamond-blackfan anemia 1EnrichmentTP531.00
263Frontotemporal dementia and/or amyotrophic lateral sclerosis 7EnrichmentHNRNPA10.98
264Parkinson disease, late-onsetEnrichmentTBP0.91
265Rare genetic deafnessEnrichmentPOLR2F0.88
266Diamond-blackfan anemiaEnrichmentTP530.82
267Primary autosomal recessive microcephalyEnrichmentTAF130.79
268West syndromeEnrichmentMLLT10.76
269HypertelorismEnrichmentMLLT10.70
270Autism spectrum disorderEnrichmentCDK130.40
271MicrocephalyEnrichmentTAF80.31

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