Formation of xylulose-5-phosphate

Sources:

#	Name	Source	Genes
1	Formation of xylulose-5-phosphate	Reactome	AKR1A1 CRYL1 DCXR SORD XYLB
2	D-glucuronate degradation	PubChem	CRYL1 DCXR
3	13q12 or CRYL1 copy number variation	WikiPathways	CRYL1
4	Essential pentosuria	Reactome	DCXR

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CRYL1	Crystallin Lambda 1	Protein Coding	3
2	DCXR	Dicarbonyl And L-Xylulose Reductase	Protein Coding	3
3	AKR1A1	Aldo-Keto Reductase Family 1 Member A1	Protein Coding	1
4	SORD	Sorbitol Dehydrogenase	Protein Coding	1
5	XYLB	Xylulokinase	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Carbohydrate metabolic disorder	Direct
2	Pentosuria	Enrichment	DCXR	3.83
3	Neuronopathy, distal hereditary motor, autosomal recessive 8	Enrichment	SORD	3.43
4	Neuromuscular disease	Enrichment	SORD	2.18

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Formation of xylulose-5-phosphate