FOXA2 pathway

No Pathway Network information available for FOXA2 pathway

#	Name	Source	Genes
1	FOXA2 pathway	WikiPathways	ABCC2 ABCC3 ABCC4 ACACA APOB FASN FOXA1 FOXA2 FOXO1 GSTA1 GSTA2 GSTM2 IRS1 IRS2 MLXIPL MTTP PPARGC1B SLC27A5 SLCO1B1 SREBF1 (see all 20) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACACA	Acetyl-CoA Carboxylase Alpha	Protein Coding	1
2	APOB	Apolipoprotein B	Protein Coding	1
3	MLXIPL	MLX Interacting Protein Like	Protein Coding	1
4	SREBF1	Sterol Regulatory Element Binding Transcription Factor 1	Protein Coding	1
5	SLC27A5	Solute Carrier Family 27 Member 5	Protein Coding	1
6	ABCC3	ATP Binding Cassette Subfamily C Member 3	Protein Coding	1
7	IRS2	Insulin Receptor Substrate 2	Protein Coding	1
8	MTTP	Microsomal Triglyceride Transfer Protein	Protein Coding	1
9	IRS1	Insulin Receptor Substrate 1	Protein Coding	1
10	FOXA2	Forkhead Box A2	Protein Coding	1
11	FOXA1	Forkhead Box A1	Protein Coding	1
12	GSTM2	Glutathione S-Transferase Mu 2	Protein Coding	1
13	GSTA2	Glutathione S-Transferase Alpha 2	Protein Coding	1
14	GSTA1	Glutathione S-Transferase Alpha 1	Protein Coding	1
15	FOXO1	Forkhead Box O1	Protein Coding	1
16	FASN	Fatty Acid Synthase	Protein Coding	1
17	PPARGC1B	PPARG Coactivator 1 Beta	Protein Coding	1
18	ABCC2	ATP Binding Cassette Subfamily C Member 2	Protein Coding	1
19	SLCO1B1	Solute Carrier Organic Anion Transporter Family Member 1B1	Protein Coding	1
20	ABCC4	ATP Binding Cassette Subfamily C Member 4 (PEL Blood Group)	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Abetalipoproteinemia	Enrichment	MTTP	2.83
2	Mucoepithelial dysplasia, hereditary	Enrichment	SREBF1	2.83
3	Acetyl-coa carboxylase-alpha deficiency	Enrichment	ACACA	2.83
4	Ifap syndrome 2	Enrichment	SREBF1	2.83
5	Non-acquired combined pituitary hormone deficiency	Enrichment	FOXA2	2.83
6	Type 2 diabetes mellitus	Enrichment	IRS1, IRS2	2.77
7	Abdominal obesity-metabolic syndrome 1	Enrichment	MTTP	2.53
8	Hypobetalipoproteinemia, familial, 1	Enrichment	APOB	2.53
9	Hypobetalipoproteinemia	Enrichment	APOB	2.53
10	Hypercholesterolemia, familial, 2	Enrichment	APOB	2.35
11	Dubin-johnson syndrome	Enrichment	ABCC2	2.35
12	Hyperbilirubinemia, rotor type	Enrichment	SLCO1B1	2.35
13	Ifap syndrome 1, with or without bresheck syndrome	Enrichment	SREBF1	2.35
14	Hyperlipidemia, familial combined, 3	Enrichment	APOB	2.13
15	Rhabdomyosarcoma 2	Enrichment	FOXO1	2.13
16	Pseudoxanthoma elasticum	Enrichment	ABCC2	2.05
17	Homozygous familial hypercholesterolemia	Enrichment	APOB	1.93
18	Combined pituitary hormone deficiency	Enrichment	FOXA2	1.93
19	Coronary heart disease 5	Enrichment	APOB	1.88
20	Gilbert syndrome	Enrichment	SLCO1B1	1.79
21	Hypercholesterolemia, familial, 1	Enrichment	APOB	1.72
22	Familial hypercholesterolemia	Enrichment	APOB	1.66
23	Diffuse large b-cell lymphoma	Enrichment	FOXO1	1.56
24	Hirschsprung disease 1	Enrichment	SREBF1	1.38

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for FOXA2 pathway