FOXM1 transcription factor network

No Pathway Network information available for FOXM1 transcription factor network

Pathways in the FOXM1 transcription factor network SuperPath

#	Name	Source	Genes
1	FOXM1 transcription factor network	PubChem	AURKB BIRC5 BRCA2 CCNB1 CCNB2 CCND1 CDC25B CDK1 CDK2 CDK4 CDKN2A CENPA CENPB CENPF CHEK2 CKS1B ESR1 ETV5 FOS FOXM1 GAS1 GSK3A H2BC1 LAMA4 MAP2K1 MMP2 MYC NEK2 NFATC3 ONECUT1 PLK1 RB1 SKP2 SP1 TGFA XRCC1 (see all 36) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	H2BC1	H2B Clustered Histone 1	Protein Coding	1
2	CENPB	Centromere Protein B	Protein Coding	1
3	ETV5	ETS Variant Transcription Factor 5	Protein Coding	1
4	NFATC3	Nuclear Factor Of Activated T Cells 3	Protein Coding	1
5	GSK3A	Glycogen Synthase Kinase 3 Alpha	Protein Coding	1
6	CCNB2	Cyclin B2	Protein Coding	1
7	CDC25B	Cell Division Cycle 25B	Protein Coding	1
8	FOXM1	Forkhead Box M1	Protein Coding	1
9	CKS1B	CDC28 Protein Kinase Regulatory Subunit 1B	Protein Coding	1
10	CENPF	Centromere Protein F	Protein Coding	1
11	CENPA	Centromere Protein A	Protein Coding	1
12	AURKB	Aurora Kinase B	Protein Coding	1
13	BIRC5	Baculoviral IAP Repeat Containing 5	Protein Coding	1
14	TGFA	Transforming Growth Factor Alpha	Protein Coding	1
15	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
16	GAS1	Growth Arrest Specific 1	Protein Coding	1
17	CCND1	Cyclin D1	Protein Coding	1
18	CHEK2	Checkpoint Kinase 2	Protein Coding	1
19	XRCC1	X-Ray Repair Cross Complementing 1	Protein Coding	1
20	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	1
21	BRCA2	BRCA2 DNA Repair Associated	Protein Coding	1
22	CDK2	Cyclin Dependent Kinase 2	Protein Coding	1
23	LAMA4	Laminin Subunit Alpha 4	Protein Coding	1
24	MMP2	Matrix Metallopeptidase 2	Protein Coding	1
25	RB1	RB Transcriptional Corepressor 1	Protein Coding	1
26	SP1	Sp1 Transcription Factor	Protein Coding	1
27	CDK4	Cyclin Dependent Kinase 4	Protein Coding	1
28	ONECUT1	One Cut Homeobox 1	Protein Coding	1
29	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
30	NEK2	NIMA Related Kinase 2	Protein Coding	1
31	CDK1	Cyclin Dependent Kinase 1	Protein Coding	1
32	PLK1	Polo Like Kinase 1	Protein Coding	1
33	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
34	SKP2	S-Phase Kinase Associated Protein 2	Protein Coding	1
35	CCNB1	Cyclin B1	Protein Coding	1
36	ESR1	Estrogen Receptor 1	Protein Coding	1

Disorders associated with FOXM1 transcription factor network SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Gastric cancer	Enrichment	BRCA2, CDK4, CDKN2A, CHEK2	5.32
2	Osteogenic sarcoma	Enrichment	CHEK2, RB1	4.69
3	Bone osteosarcoma	Enrichment	CHEK2, RB1	4.69
4	Inherited cancer-predisposing syndrome	Enrichment	BRCA2, CDK4, CDKN2A, CHEK2, RB1	4.62
5	Pancreatic cancer	Enrichment	BRCA2, CDKN2A, CHEK2	4.42
6	Breast cancer	Enrichment	BRCA2, CHEK2, CKS1B, ESR1	4.35
7	Bladder cancer	Enrichment	BRCA2, CDKN2A, RB1	4.22
8	Li-fraumeni syndrome	Enrichment	CDKN2A, CHEK2	3.99
9	Ovarian cancer	Enrichment	BRCA2, CDKN2A, CHEK2, RB1	3.85
10	Hereditary breast carcinoma	Enrichment	BRCA2, CHEK2, ESR1	3.68
11	Melanoma	Enrichment	CDKN2A, CHEK2	3.52
12	Uterine corpus cancer	Enrichment	BRCA2, CHEK2	3.43
13	Familial colorectal cancer type x	Enrichment	BRCA2, CHEK2	3.43
14	Lip and oral cavity carcinoma	Enrichment	CDKN2A, RB1	3.35
15	Breast-ovarian cancer, familial 1	Enrichment	BRCA2, CHEK2	3.28
16	Nk-cell enteropathy	Enrichment	AURKB, CHEK2	3.28
17	Wilms tumor 1	Enrichment	BRCA2, CHEK2	3.15
18	Melanoma, cutaneous malignant 1	Enrichment	CDK4, CDKN2A	3.04
19	Diffuse large b-cell lymphoma	Enrichment	BRCA2, CHEK2	2.94
20	Endometrial cancer	Enrichment	BRCA2, CHEK2	2.86
21	Colorectal cancer	Enrichment	BRCA2, CCND1, CHEK2	2.81
22	Precursor t-cell acute lymphoblastic leukemia	Enrichment	CDKN2A, MYC	2.78
23	Melanoma, cutaneous malignant 3	Enrichment	CDK4	2.58
24	Melorheostosis, isolated	Enrichment	MAP2K1	2.58
25	Cardiomyopathy, dilated, 1jj	Enrichment	LAMA4	2.58
26	Glioma susceptibility 3	Enrichment	BRCA2	2.58
27	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.58
28	Pancreatic cancer 2	Enrichment	BRCA2	2.58
29	Tumor predisposition syndrome 4	Enrichment	CHEK2	2.58
30	Melorheostosis	Enrichment	MAP2K1	2.58
31	Retinitis pigmentosa 67	Enrichment	NEK2	2.58
32	Leiomyosarcoma	Enrichment	CHEK2	2.58
33	Spinocerebellar ataxia, autosomal recessive 26	Enrichment	XRCC1	2.58
34	Trilateral retinoblastoma	Enrichment	RB1	2.58
35	Cdkn2a cancer predisposition	Enrichment	CDKN2A	2.58
36	Lung oat cell carcinoma	Enrichment	RB1	2.58
37	Prostate cancer	Enrichment	BRCA2, CHEK2	2.58
38	Melanoma-astrocytoma syndrome	Enrichment	CDKN2A	2.28
39	Burkitt lymphoma	Enrichment	MYC	2.28
40	Stromme syndrome	Enrichment	CENPF	2.28
41	Melanoma, cutaneous malignant 2	Enrichment	CDKN2A	2.28
42	Chromosome 13q14 deletion syndrome	Enrichment	RB1	2.28
43	Congenital heart defects, multiple types, 3	Enrichment	CHEK2	2.28
44	Diffuse midline glioma, h3 k27m-mutant	Enrichment	BRCA2	2.28
45	Melanoma-pancreatic cancer syndrome	Enrichment	CDKN2A	2.28
46	Li-fraumeni syndrome 1	Enrichment	CHEK2	2.28
47	Sarcoma	Enrichment	CHEK2	2.28
48	Fanconi anemia, complementation group d1	Enrichment	BRCA2	2.28
49	Inflammatory breast carcinoma	Enrichment	BRCA2	2.28
50	Bilateral breast cancer	Enrichment	BRCA2	2.28
51	Familial retinoblastoma	Enrichment	RB1	2.28
52	Neuroendocrine tumor of pancreas	Enrichment	BRCA2	2.28
53	Retinoblastoma	Enrichment	RB1	2.10
54	Multicentric osteolysis, nodulosis, and arthropathy	Enrichment	MMP2	2.10
55	Langerhans cell histiocytosis	Enrichment	MAP2K1	2.10
56	Estrogen resistance	Enrichment	ESR1	2.10
57	Woolly hair, autosomal recessive 3	Enrichment	RB1	2.10
58	Tumor predisposition syndrome 1	Enrichment	BRCA2	2.10
59	Hypotrichosis 8	Enrichment	RB1	2.10
60	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	2.10
61	Dedifferentiated liposarcoma	Enrichment	CDK4	2.10
62	Squamous cell carcinoma	Enrichment	RB1	2.10
63	Migraine without aura	Enrichment	ESR1	2.10
64	Bap1 tumor predisposition syndrome	Enrichment	BRCA2	2.10
65	Well-differentiated liposarcoma	Enrichment	CDK4	2.10
66	Hereditary breast ovarian cancer syndrome	Enrichment	BRCA2, CHEK2	2.03
67	Myeloma, multiple	Enrichment	BRCA2, CCND1	2.02
68	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1	1.98
69	Small cell cancer of the lung	Enrichment	RB1	1.98
70	Cystinuria	Enrichment	CENPF	1.98
71	Chordoma	Enrichment	BRCA2	1.98
72	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA2	1.98
73	Cholangiocarcinoma	Enrichment	BRCA2	1.98
74	Ciliary dyskinesia, primary, 29	Enrichment	CENPF	1.98
75	Lynch syndrome 4	Enrichment	RB1	1.98
76	Congenital generalized lipodystrophy	Enrichment	FOS	1.98
77	Mantle cell lymphoma	Enrichment	CCND1	1.98
78	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	1.98
79	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1	1.98
80	Hemoglobin c disease	Enrichment	CHEK2	1.98
81	Von hippel-lindau syndrome	Enrichment	CCND1	1.88
82	Breast-ovarian cancer, familial 2	Enrichment	BRCA2	1.88
83	Histiocytoid hemangioma	Enrichment	FOS	1.88
84	Kabuki syndrome 1	Enrichment	BRCA2	1.80
85	Wilms tumor 5	Enrichment	CHEK2	1.80
86	Adrenocortical carcinoma	Enrichment	CDKN2A	1.80
87	Lung squamous cell carcinoma	Enrichment	CDKN2A	1.80
88	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1	1.73
89	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	CDKN2A	1.73
90	Isolated growth hormone deficiency, type ia	Enrichment	BRCA2	1.68
91	Tracheoesophageal fistula with or without esophageal atresia	Enrichment	BRCA2	1.63
92	Polydactyly	Enrichment	BRCA2	1.63
93	Arteriovenous malformation	Enrichment	MAP2K1	1.63
94	Colonic benign neoplasm	Enrichment	CHEK2	1.63
95	Lynch syndrome 1	Enrichment	CHEK2	1.58
96	Leukemia, chronic lymphocytic	Enrichment	CCND1	1.58
97	Myopathy, x-linked, with excessive autophagy	Enrichment	MAP2K1	1.58
98	Isolated tracheo-esophageal fistula	Enrichment	BRCA2	1.58
99	Migraine with or without aura 1	Enrichment	ESR1	1.54
100	Leukemia, acute lymphoblastic	Enrichment	CDKN2A	1.54
101	Lung non-small cell carcinoma	Enrichment	MAP2K1	1.54
102	Medulloblastoma	Enrichment	BRCA2	1.44
103	Lung cancer susceptibility 3	Enrichment	RB1	1.44
104	Lynch syndrome	Enrichment	CHEK2	1.41
105	Septopreoptic holoprosencephaly	Enrichment	GAS1	1.41
106	Midline interhemispheric variant of holoprosencephaly	Enrichment	GAS1	1.41
107	Noonan syndrome and noonan-related syndrome	Enrichment	MAP2K1	1.41
108	Rhabdomyosarcoma	Enrichment	BRCA2	1.38
109	Microform holoprosencephaly	Enrichment	GAS1	1.38
110	Lobar holoprosencephaly	Enrichment	GAS1	1.38
111	Alobar holoprosencephaly	Enrichment	GAS1	1.35
112	Semilobar holoprosencephaly	Enrichment	GAS1	1.33
113	Esophageal atresia/tracheoesophageal fistula	Enrichment	BRCA2	1.31
114	Hepatoblastoma	Enrichment	BRCA2	1.27
115	Myocardial infarction	Enrichment	ESR1	1.25
116	Tooth agenesis	Enrichment	TGFA	1.25
117	Noonan syndrome 1	Enrichment	MAP2K1	1.23
118	Rasopathy	Enrichment	MAP2K1	1.18
119	Severe covid-19	Enrichment	CENPF	1.13
120	Lung cancer	Enrichment	CHEK2	1.09
121	Fanconi anemia, complementation group a	Enrichment	BRCA2	1.05
122	Cerebral palsy	Enrichment	BRCA2	1.01
123	Familial isolated dilated cardiomyopathy	Enrichment	LAMA4	0.88
124	Primary ovarian insufficiency	Enrichment	CHEK2	0.84
125	Autism spectrum disorder	Enrichment	MAP2K1	0.60
126	Retinitis pigmentosa	Enrichment	NEK2	0.36
127	Hereditary retinal dystrophy	Enrichment	NEK2	0.27
128	Fundus dystrophy	Enrichment	NEK2	0.27

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

FOXM1 transcription factor network

Pathway Network for FOXM1 transcription factor network

Member Pathways for FOXM1 transcription factor network

Pathways in the FOXM1 transcription factor network SuperPath

Associated Genes for FOXM1 transcription factor network

Associated Disorders for FOXM1 transcription factor network

Disorders associated with FOXM1 transcription factor network SuperPath

STRING Interaction Network for FOXM1 transcription factor network

Sources for FOXM1 transcription factor network