G-protein signaling_Rap1B regulation pathway

No Pathway Network information available for G-protein signaling_Rap1B regulation pathway

#	Name	Source	Genes
1	G-protein signaling_Rap1B regulation pathway	GeneGo (Thomson Reuters)	ATP2A3 FNTA GRB2 KIFAP3 PGGT1B PRKACA PRKACB PRKACG RAP1B RAP1GDS1 RAPGEF1 RASA3 RCE1 TSC2 (see all 14) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ATP2A3	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 3	Protein Coding	1
2	FNTA	Farnesyltransferase, CAAX Box, Subunit Alpha	Protein Coding	1
3	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	1
4	RAPGEF1	Rap Guanine Nucleotide Exchange Factor 1	Protein Coding	1
5	PGGT1B	Protein Geranylgeranyltransferase Type I Subunit Beta	Protein Coding	1
6	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
7	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
8	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	1
9	RAP1B	RAP1B, Member Of RAS Oncogene Family	Protein Coding	1
10	RAP1GDS1	Rap1 GTPase-GDP Dissociation Stimulator 1	Protein Coding	1
11	TSC2	TSC Complex Subunit 2	Protein Coding	1
12	RCE1	Ras Converting CAAX Endopeptidase 1	Protein Coding	1
13	RASA3	RAS P21 Protein Activator 3	Protein Coding	1
14	KIFAP3	Kinesin Associated Protein 3	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	4.45
2	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	2.99
3	Thrombocytopenia 11 with multiple congenital anomalies and dysmorphic facies	Enrichment	RAP1B	2.99
4	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	2.99
5	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	2.99
6	Alfadhel syndrome	Enrichment	RAP1GDS1	2.99
7	Lymphangioleiomyomatosis	Enrichment	TSC2	2.69
8	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	2.69
9	Fibrolamellar carcinoma	Enrichment	PRKACA	2.69
10	Tuberous sclerosis 1	Enrichment	TSC2	2.51
11	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	2.51
12	Tuberous sclerosis 2	Enrichment	TSC2	2.51
13	Hamartoma	Enrichment	TSC2	2.51
14	Xanthinuria, type ii	Enrichment	TSC2	2.51
15	Focal cortical dysplasia, type ii	Enrichment	TSC2	2.38
16	Tuberous sclerosis	Enrichment	TSC2	2.38
17	Isolated focal cortical dysplasia type ii	Enrichment	TSC2	2.38
18	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	2.14
19	Polycystic kidney disease 1	Enrichment	TSC2	2.14
20	Adult hepatocellular carcinoma	Enrichment	TSC2	2.03
21	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	1.81
22	West syndrome	Enrichment	TSC2	1.35
23	Ovarian cancer	Enrichment	TSC2	1.00
24	Congenital nervous system abnormality	Enrichment	TSC2	0.98
25	Nervous system disease	Enrichment	TSC2	0.98
26	Autism spectrum disorder	Enrichment	TSC2	0.97
27	Inherited cancer-predisposing syndrome	Enrichment	TSC2	0.89

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for G-protein signaling_Rap1B regulation pathway