G alpha (s) signalling events

No Pathway Network information available for G alpha (s) signalling events

Pathways in the G alpha (s) signalling events SuperPath

#	Name	Source	Genes
1	G alpha (s) signalling events	Reactome	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCYAP1 ADCYAP1R1 ADM ADM2 ADORA2A ADORA2B ADRB1 ADRB2 ADRB3 ARRB1 ARRB2 AVP AVPR2 CALCA CALCB CALCR CALCRL CGA CRH CRHR1 CRHR2 CYSLTR2 DRD1 DRD5 FN1 FSHB FSHR GCG GCGR GHRH GHRHR GIP GIPR GLP1R GLP2R GNAI1 GNAI2 GNAI3 GNAS GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GPBAR1 GPER1 GPHA2 GPHB5 GPR15 GPR150 GPR176 GPR20 GPR25 GPR27 GPR32 GPR39 GPR45 GPR83 GPR84 GRK2 GRK3 GRK5 GRK6 HRH2 HTR4 HTR6 HTR7 IAPP INSL3 ITGA5 ITGB1 LHB LHCGR MC1R MC2R MC3R MC4R MC5R NPS NPSR1 P2RY11 PDE10A PDE11A PDE1A PDE1B PDE2A PDE3A PDE3B PDE4A PDE4C PDE4D PDE7A PDE7B PDE8A PDE8B POMC PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PTGDR PTGER2 PTGER4 PTGIR PTH PTH1R PTH2 PTH2R PTHLH RAMP1 RAMP2 RAMP3 RLN2 RLN3 RXFP1 RXFP2 SCT SCTR SHC1 SRC TAAR1 TAAR2 TAAR5 TAAR6 TAAR8 TAAR9 TSHB TSHR VIP VIPR1 VIPR2 (see all 157) (see less)
2	Defective ACTH causes obesity and POMCD	Reactome	MC2R POMC

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	MC2R	Melanocortin 2 Receptor	Protein Coding	2
2	POMC	Proopiomelanocortin	Protein Coding	2
3	CALCRL	Calcitonin Receptor Like Receptor	Protein Coding	1
4	RAMP2	Receptor Activity Modifying Protein 2	Protein Coding	1
5	RAMP1	Receptor Activity Modifying Protein 1	Protein Coding	1
6	RAMP3	Receptor Activity Modifying Protein 3	Protein Coding	1
7	GNB5	G Protein Subunit Beta 5	Protein Coding	1
8	ADCY1	Adenylate Cyclase 1	Protein Coding	1
9	ADCY2	Adenylate Cyclase 2	Protein Coding	1
10	CGA	Glycoprotein Hormones, Alpha Polypeptide	Protein Coding	1
11	PDE10A	Phosphodiesterase 10A	Protein Coding	1
12	GPR83	G Protein-Coupled Receptor 83	Protein Coding	1
13	ADCY3	Adenylate Cyclase 3	Protein Coding	1
14	ADCY5	Adenylate Cyclase 5	Protein Coding	1
15	ADCY6	Adenylate Cyclase 6	Protein Coding	1
16	GPR176	G Protein-Coupled Receptor 176	Protein Coding	1
17	GPR45	G Protein-Coupled Receptor 45	Protein Coding	1
18	ADCY7	Adenylate Cyclase 7	Protein Coding	1
19	PTH2	Parathyroid Hormone 2	Protein Coding	1
20	ADCY8	Adenylate Cyclase 8	Protein Coding	1
21	ADCY9	Adenylate Cyclase 9	Protein Coding	1
22	ADCYAP1	Adenylate Cyclase Activating Polypeptide 1	Protein Coding	1
23	ADCYAP1R1	ADCYAP Receptor Type I	Protein Coding	1
24	RLN3	Relaxin 3	Protein Coding	1
25	RXFP2	Relaxin Family Peptide Receptor 2	Protein Coding	1
26	GPHB5	Glycoprotein Hormone Subunit Beta 5	Protein Coding	1
27	ADM	Adrenomedullin	Protein Coding	1
28	TAAR9	Trace Amine Associated Receptor 9	Protein Coding	1
29	TAAR1	Trace Amine Associated Receptor 1	Protein Coding	1
30	ADORA2A	Adenosine A2a Receptor	Protein Coding	1
31	ADORA2B	Adenosine A2b Receptor	Protein Coding	1
32	CRH	Corticotropin Releasing Hormone	Protein Coding	1
33	CRHR1	Corticotropin Releasing Hormone Receptor 1	Protein Coding	1
34	CRHR2	Corticotropin Releasing Hormone Receptor 2	Protein Coding	1
35	GPBAR1	G Protein-Coupled Bile Acid Receptor 1	Protein Coding	1
36	ADRB1	Adrenoceptor Beta 1	Protein Coding	1
37	ADRB2	Adrenoceptor Beta 2	Protein Coding	1
38	ADRB3	Adrenoceptor Beta 3	Protein Coding	1
39	GRK2	G Protein-Coupled Receptor Kinase 2	Protein Coding	1
40	GRK3	G Protein-Coupled Receptor Kinase 3	Protein Coding	1
41	GPHA2	Glycoprotein Hormone Subunit Alpha 2	Protein Coding	1
42	DRD1	Dopamine Receptor D1	Protein Coding	1
43	DRD5	Dopamine Receptor D5	Protein Coding	1
44	ADCY4	Adenylate Cyclase 4	Protein Coding	1
45	FN1	Fibronectin 1	Protein Coding	1
46	FSHB	Follicle Stimulating Hormone Subunit Beta	Protein Coding	1
47	FSHR	Follicle Stimulating Hormone Receptor	Protein Coding	1
48	GCG	Glucagon	Protein Coding	1
49	GCGR	Glucagon Receptor	Protein Coding	1
50	GHRH	Growth Hormone Releasing Hormone	Protein Coding	1
51	GHRHR	Growth Hormone Releasing Hormone Receptor	Protein Coding	1
52	GIP	Gastric Inhibitory Polypeptide	Protein Coding	1
53	GIPR	Gastric Inhibitory Polypeptide Receptor	Protein Coding	1
54	PDE7B	Phosphodiesterase 7B	Protein Coding	1
55	GLP1R	Glucagon Like Peptide 1 Receptor	Protein Coding	1
56	GNAI1	G Protein Subunit Alpha I1	Protein Coding	1
57	GNAI2	G Protein Subunit Alpha I2	Protein Coding	1
58	GNAI3	G Protein Subunit Alpha I3	Protein Coding	1
59	GNAS	GNAS Complex Locus	Protein Coding	1
60	GNAZ	G Protein Subunit Alpha Z	Protein Coding	1
61	GNB1	G Protein Subunit Beta 1	Protein Coding	1
62	GNB2	G Protein Subunit Beta 2	Protein Coding	1
63	GNB3	G Protein Subunit Beta 3	Protein Coding	1
64	GNG3	G Protein Subunit Gamma 3	Protein Coding	1
65	GNG4	G Protein Subunit Gamma 4	Protein Coding	1
66	GNG5	G Protein Subunit Gamma 5	Protein Coding	1
67	GNG7	G Protein Subunit Gamma 7	Protein Coding	1
68	GNG10	G Protein Subunit Gamma 10	Protein Coding	1
69	GNG11	G Protein Subunit Gamma 11	Protein Coding	1
70	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	1
71	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	1
72	GPR15	G Protein-Coupled Receptor 15	Protein Coding	1
73	GPR20	G Protein-Coupled Receptor 20	Protein Coding	1
74	GPR25	G Protein-Coupled Receptor 25	Protein Coding	1
75	GPR27	G Protein-Coupled Receptor 27	Protein Coding	1
76	GPER1	G Protein-Coupled Estrogen Receptor 1	Protein Coding	1
77	GPR32	G Protein-Coupled Receptor 32	Protein Coding	1
78	GPR150	G Protein-Coupled Receptor 150	Protein Coding	1
79	GPR39	G Protein-Coupled Receptor 39	Protein Coding	1
80	GRK5	G Protein-Coupled Receptor Kinase 5	Protein Coding	1
81	GRK6	G Protein-Coupled Receptor Kinase 6	Protein Coding	1
82	TAAR6	Trace Amine Associated Receptor 6	Protein Coding	1
83	HRH2	Histamine Receptor H2	Protein Coding	1
84	HTR4	5-Hydroxytryptamine Receptor 4	Protein Coding	1
85	HTR6	5-Hydroxytryptamine Receptor 6	Protein Coding	1
86	HTR7	5-Hydroxytryptamine Receptor 7	Protein Coding	1
87	IAPP	Islet Amyloid Polypeptide	Protein Coding	1
88	GNAT3	G Protein Subunit Alpha Transducin 3	Protein Coding	1
89	INSL3	Insulin Like 3	Protein Coding	1
90	ITGA5	Integrin Subunit Alpha 5	Protein Coding	1
91	ITGB1	Integrin Subunit Beta 1	Protein Coding	1
92	NPSR1	Neuropeptide S Receptor 1	Protein Coding	1
93	LHB	Luteinizing Hormone Subunit Beta	Protein Coding	1
94	LHCGR	Luteinizing Hormone/Choriogonadotropin Receptor	Protein Coding	1
95	ARRB1	Arrestin Beta 1	Protein Coding	1
96	ARRB2	Arrestin Beta 2	Protein Coding	1
97	MC1R	Melanocortin 1 Receptor	Protein Coding	1
98	MC3R	Melanocortin 3 Receptor	Protein Coding	1
99	MC4R	Melanocortin 4 Receptor	Protein Coding	1
100	MC5R	Melanocortin 5 Receptor	Protein Coding	1
101	P2RY11	Purinergic Receptor P2Y11	Protein Coding	1
102	PDE11A	Phosphodiesterase 11A	Protein Coding	1
103	PDE1A	Phosphodiesterase 1A	Protein Coding	1
104	PDE2A	Phosphodiesterase 2A	Protein Coding	1
105	PDE3A	Phosphodiesterase 3A	Protein Coding	1
106	PDE3B	Phosphodiesterase 3B	Protein Coding	1
107	PDE4A	Phosphodiesterase 4A	Protein Coding	1
108	PDE4C	Phosphodiesterase 4C	Protein Coding	1
109	PDE4D	Phosphodiesterase 4D	Protein Coding	1
110	PDE7A	Phosphodiesterase 7A	Protein Coding	1
111	PDE8A	Phosphodiesterase 8A	Protein Coding	1
112	PDE1B	Phosphodiesterase 1B	Protein Coding	1
113	GNG13	G Protein Subunit Gamma 13	Protein Coding	1
114	GPR84	G Protein-Coupled Receptor 84	Protein Coding	1
115	GNG2	G Protein Subunit Gamma 2	Protein Coding	1
116	AVP	Arginine Vasopressin	Protein Coding	1
117	AVPR2	Arginine Vasopressin Receptor 2	Protein Coding	1
118	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
119	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
120	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	1
121	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	1
122	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	1
123	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	1
124	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	1
125	GNG12	G Protein Subunit Gamma 12	Protein Coding	1
126	CYSLTR2	Cysteinyl Leukotriene Receptor 2	Protein Coding	1
127	PTGDR	Prostaglandin D2 Receptor	Protein Coding	1
128	PTGER2	Prostaglandin E Receptor 2	Protein Coding	1
129	PTGER4	Prostaglandin E Receptor 4	Protein Coding	1
130	PTGIR	Prostaglandin I2 Receptor	Protein Coding	1
131	PTH	Parathyroid Hormone	Protein Coding	1
132	PTHLH	Parathyroid Hormone Like Hormone	Protein Coding	1
133	PTH1R	Parathyroid Hormone 1 Receptor	Protein Coding	1
134	PTH2R	Parathyroid Hormone 2 Receptor	Protein Coding	1
135	GNB4	G Protein Subunit Beta 4	Protein Coding	1
136	RXFP1	Relaxin Family Peptide Receptor 1	Protein Coding	1
137	NPS	Neuropeptide S	Protein Coding	1
138	RLN2	Relaxin 2	Protein Coding	1
139	SCT	Secretin	Protein Coding	1
140	SCTR	Secretin Receptor	Protein Coding	1
141	SHC1	SHC Adaptor Protein 1	Protein Coding	1
142	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
143	TSHB	Thyroid Stimulating Hormone Subunit Beta	Protein Coding	1
144	TSHR	Thyroid Stimulating Hormone Receptor	Protein Coding	1
145	VIP	Vasoactive Intestinal Peptide	Protein Coding	1
146	VIPR1	Vasoactive Intestinal Peptide Receptor 1	Protein Coding	1
147	VIPR2	Vasoactive Intestinal Peptide Receptor 2	Protein Coding	1
148	CALCA	Calcitonin Related Polypeptide Alpha	Protein Coding	1
149	CALCB	Calcitonin Related Polypeptide Beta	Protein Coding	1
150	CALCR	Calcitonin Receptor	Protein Coding	1
151	ADM2	Adrenomedullin 2	Protein Coding	1
152	TAAR8	Trace Amine Associated Receptor 8	Protein Coding	1
153	PDE8B	Phosphodiesterase 8B	Protein Coding	1
154	TAAR5	Trace Amine Associated Receptor 5	Protein Coding	1
155	TAAR2	Trace Amine Associated Receptor 2	Protein Coding	1
156	GLP2R	Glucagon Like Peptide 2 Receptor	Protein Coding	1
157	GNG8	G Protein Subunit Gamma 8	Protein Coding	1

Disorders associated with G alpha (s) signalling events SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Adrenal gland disease	Direct
2	Body mass index quantitative trait locus 11	Direct
3	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	GNAS, PRKAR1A	3.88
4	Acrodysostosis	Enrichment	PDE4D, PRKAR1A	3.88
5	Pseudohypoparathyroidism	Enrichment	GNAS, PTH1R	3.88
6	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PDE11A, PRKAR1A	3.88
7	Isolated micronodular adrenocortical disease	Enrichment	PDE11A, PDE8B	3.88
8	Brachydactyly, type e1	Enrichment	PTH1R, PTHLH	3.40
9	Carney complex variant	Enrichment	PDE11A, PRKAR1A	3.10
10	Cryptorchidism, unilateral or bilateral	Enrichment	INSL3, RXFP2	2.34
11	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	2.34
12	Osteoporosis	Enrichment	CALCR, SRC	1.96
13	Diabetes insipidus, neurohypophyseal	Enrichment	AVP	1.94
14	Hypertension and brachydactyly syndrome	Enrichment	PDE3A	1.94
15	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	1.94
16	Body mass index quantitative trait locus 9	Enrichment	MC3R	1.94
17	Nephrogenic syndrome of inappropriate antidiuresis	Enrichment	AVPR2	1.94
18	Diabetes insipidus, nephrogenic, 1, x-linked	Enrichment	AVPR2	1.94
19	Asthma-related traits 1	Enrichment	PTGDR	1.94
20	Pseudohypoparathyroidism, type ic	Enrichment	GNAS	1.94
21	Striatal degeneration, autosomal dominant 1	Enrichment	PDE8B	1.94
22	Carney complex, type 1	Enrichment	PRKAR1A	1.94
23	Resting heart rate, variation in	Enrichment	ADRB1	1.94
24	Blepharospasm, benign essential	Enrichment	DRD5	1.94
25	Osseous heteroplasia, progressive	Enrichment	GNAS	1.94
26	Dyskinesia with orofacial involvement, autosomal dominant	Enrichment	ADCY5	1.94
27	Increased analgesia from kappa-opioid receptor agonist, female-specific	Enrichment	MC1R	1.94
28	Dyskinesia, limb and orofacial, infantile-onset	Enrichment	PDE10A	1.94
29	Deafness, autosomal recessive 44	Enrichment	ADCY1	1.94
30	Hypogonadotropic hypogonadism 23 with or without anosmia	Enrichment	LHB	1.94
31	Ovarian dysgenesis 1	Enrichment	FSHR	1.94
32	Ventricular tachycardia, familial	Enrichment	GNAI2	1.94
33	Acth-independent macronodular adrenal hyperplasia 1	Enrichment	GNAS	1.94
34	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	1.94
35	Twinning, dizygotic	Enrichment	FSHR	1.94
36	Neurodevelopmental disorder with hyperkinetic movements and dyskinesia	Enrichment	ADCY5	1.94
37	Pituitary adenoma 3, multiple types	Enrichment	GNAS	1.94
38	Skin/hair/eye pigmentation, variation in, 2	Enrichment	MC1R	1.94
39	Hypothyroidism, congenital, nongoitrous, 4	Enrichment	TSHB	1.94
40	Body mass index quantitative trait locus 20	Enrichment	MC4R	1.94
41	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	1.94
42	Intellectual developmental disorder with paroxysmal dyskinesia or seizures	Enrichment	PDE2A	1.94
43	Central diabetes insipidus	Enrichment	AVP	1.94
44	Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities	Enrichment	GNAI1	1.94
45	Myxoma, intracardiac	Enrichment	PRKAR1A	1.94
46	X-linked nephrogenic diabetes insipidus	Enrichment	AVPR2	1.94
47	Dyskinesia with orofacial involvement, autosomal recessive	Enrichment	ADCY5	1.94
48	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	1.94
49	Ovarian hyperstimulation syndrome	Enrichment	FSHR	1.94
50	Acrodysostosis 2 with or without hormone resistance	Enrichment	PDE4D	1.94
51	Amenorrhea	Enrichment	FSHR	1.94
52	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	1.94
53	Melanoma, cutaneous malignant 5	Enrichment	MC1R	1.94
54	Brachydactyly, type e2	Enrichment	PTHLH	1.94
55	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	1.94
56	Disorders of gnas inactivation	Enrichment	GNAS	1.94
57	Schizophrenia 16	Enrichment	VIPR2	1.94
58	Pigmented nodular adrenocortical disease, primary, 3	Enrichment	PDE8B	1.94
59	Striatal degeneration, autosomal dominant 2	Enrichment	PDE10A	1.94
60	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	1.94
61	Mahvash disease	Enrichment	GCGR	1.94
62	Thrombocytopenia 6	Enrichment	SRC	1.94
63	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	1.94
64	Isolated growth hormone deficiency, type iv	Enrichment	GHRHR	1.94
65	Sick sinus syndrome 4	Enrichment	GNB2	1.94
66	Short sleep, familial natural, 2	Enrichment	ADRB1	1.94
67	Obesity due to melanocortin 4 receptor deficiency	Enrichment	MC4R	1.94
68	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	1.94
69	Striatal degeneration, autosomal dominant	Enrichment	PDE8B	1.94
70	Acute encephalopathy with biphasic seizures and late reduced diffusion	Enrichment	ADORA2A	1.94
71	Short sleep, familial natural, 3	Enrichment	NPSR1	1.94
72	Monostotic fibrous dysplasia	Enrichment	GNAS	1.94
73	Mazabraud syndrome	Enrichment	GNAS	1.94
74	Childhood-onset benign chorea with striatal involvement	Enrichment	PDE10A	1.94
75	Hereditary arginine vasopressin deficiency	Enrichment	AVP	1.94
76	Blepharospasm	Enrichment	DRD5	1.94
77	Failure of tooth eruption, primary	Enrichment	PTH1R	1.64
78	Hypoparathyroidism, familial isolated, 1	Enrichment	PTH	1.64
79	Pseudohypoparathyroidism, type ia	Enrichment	GNAS	1.64
80	Precocious puberty, male-limited	Enrichment	LHCGR	1.64
81	Glucocorticoid deficiency 1	Enrichment	MC2R	1.64
82	Metaphyseal chondrodysplasia, jansen type	Enrichment	PTH1R	1.64
83	Spondyloepimetaphyseal dysplasia, strudwick type	Enrichment	FN1	1.64
84	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	1.64
85	Spondylometaphyseal dysplasia, corner fracture type	Enrichment	FN1	1.64
86	Pituitary adenoma 4, acth-secreting	Enrichment	GNAI2	1.64
87	Leydig cell hypoplasia, type i	Enrichment	LHCGR	1.64
88	Chondrodysplasia, blomstrand type	Enrichment	PTH1R	1.64
89	Hypogonadotropic hypogonadism 24 with or without anosmia	Enrichment	FSHB	1.64
90	Hyperthyroidism, familial gestational	Enrichment	TSHR	1.64
91	Eiken syndrome	Enrichment	PTH1R	1.64
92	Vitamin d hydroxylation-deficient rickets, type 1b	Enrichment	PDE3B	1.64
93	Pseudopseudohypoparathyroidism	Enrichment	GNAS	1.64
94	Lethal congenital contracture syndrome 8	Enrichment	ADCY6	1.64
95	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.64
96	Chromosome 5q12 deletion syndrome	Enrichment	PDE4D	1.64
97	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.64
98	Pigmented nodular adrenocortical disease, primary, 2	Enrichment	PDE11A	1.64
99	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	1.64
100	Usher syndrome, type iv	Enrichment	PRKAR1A	1.64
101	Body mass index quantitative trait locus 19	Enrichment	ADCY3	1.64
102	Fibrolamellar carcinoma	Enrichment	PRKACA	1.64
103	Lymphatic malformation 8	Enrichment	CALCRL	1.64
104	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	1.64
105	Hypopituitarism	Enrichment	GNAI2	1.64
106	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.64
107	Leydig cell hypoplasia type ii	Enrichment	LHCGR	1.64
108	Acth-independent macronodular adrenal hyperplasia	Enrichment	GNAS	1.64
109	Cerebral visual impairment	Enrichment	GNB1	1.64
110	Attention deficit-hyperactivity disorder	Enrichment	DRD5, GNB5	1.58
111	Mccune-albright syndrome	Enrichment	GNAS	1.46
112	Asthma, nasal polyps, and aspirin intolerance	Enrichment	PTGER2	1.46
113	Vitamin d hydroxylation-deficient rickets, type 1a	Enrichment	PDE3B	1.46
114	Glomerulopathy with fibronectin deposits 2	Enrichment	FN1	1.46
115	Obesity, early-onset, with adrenal insufficiency and red hair	Enrichment	POMC	1.46
116	Hyperthyroidism, nonautoimmune	Enrichment	TSHR	1.46
117	Hypothyroidism, congenital, nongoitrous, 1	Enrichment	TSHR	1.46
118	Familial isolated hypoparathyroidism	Enrichment	PTH	1.46
119	Isolated growth hormone deficiency, type ib	Enrichment	GHRHR	1.46
120	Gonadal dysgenesis	Enrichment	FSHR	1.46
121	Nephrogenic diabetes insipidus	Enrichment	AVPR2	1.46
122	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	GNAS	1.46
123	Familial hyperthyroidism due to mutations in tsh receptor	Enrichment	TSHR	1.46
124	Hypomyelination neuropathy-arthrogryposis syndrome	Enrichment	ADCY6	1.46
125	Obesity due to pro-opiomelanocortin deficiency	Enrichment	POMC	1.46
126	Chorea, benign hereditary	Enrichment	ADCY5	1.34
127	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.34
128	Pseudohypoparathyroidism, type ib	Enrichment	GNAS	1.34
129	Smith-lemli-opitz syndrome	Enrichment	TSHR	1.34
130	Auriculocondylar syndrome 1	Enrichment	GNAI3	1.34
131	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.34
132	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	1.34
133	Bone mineral density quantitative trait locus 15	Enrichment	CALCR	1.34
134	Achromatopsia 4	Enrichment	GNAI3	1.34
135	Diabetes insipidus	Enrichment	AVP	1.34
136	Primary hyperparathyroidism	Enrichment	PTH	1.34
137	Familial sick sinus syndrome	Enrichment	GNB2	1.34
138	Enchondromatosis, multiple, ollier type	Enrichment	PTH1R	1.25
139	Albinism, oculocutaneous, type ii	Enrichment	MC1R	1.25
140	Convulsions, familial infantile, with paroxysmal choreoathetosis	Enrichment	PDE2A	1.25
141	Pseudohermaphroditism	Enrichment	LHCGR	1.25
142	Familial glucocorticoid deficiency	Enrichment	MC2R	1.25
143	Melanoma, uveal	Enrichment	CYSLTR2	1.17
144	Adrenocortical carcinoma	Enrichment	PRKAR1A	1.17
145	Hypothyroidism, congenital, nongoitrous, 2	Enrichment	TSHR	1.11
146	Myelofibrosis	Enrichment	SRC	1.11
147	Brachydactyly	Enrichment	GNAS	1.11
148	Autosomal dominant sleep-related hypermotor epilepsy	Enrichment	CRH	1.11
149	Paroxysmal dystonia	Enrichment	PDE2A	1.11
150	Narcolepsy 1	Enrichment	P2RY11	1.05
151	Spastic paraplegia 4, autosomal dominant	Enrichment	GNAS	1.05
152	Cryptorchidism	Enrichment	INSL3	1.05
153	Hypothyroidism	Enrichment	GNB1	1.05
154	Choreatic disease	Enrichment	PDE2A	1.05
155	Primary hyperaldosteronism	Enrichment	GNAS	1.00
156	Melanoma	Enrichment	MC1R	0.96
157	Leukemia, acute lymphoblastic	Enrichment	GNB1	0.92
158	Myelodysplastic syndrome	Enrichment	GNB1	0.92
159	Congenital hypothyroidism	Enrichment	TSHR	0.88
160	46 xx gonadal dysgenesis	Enrichment	FSHR	0.88
161	Neural tube defects	Enrichment	ITGB1	0.85
162	Pulmonary disease, chronic obstructive	Enrichment	PDE3B	0.85
163	Acute promyelocytic leukemia	Enrichment	PRKAR1A	0.85
164	Perrault syndrome 1	Enrichment	FSHR	0.77
165	Hypertension, essential	Enrichment	GNB3	0.75
166	Melanoma, cutaneous malignant 1	Enrichment	MC1R	0.75
167	Cleft palate, isolated	Enrichment	GNB1	0.75
168	Syndromic intellectual disability	Enrichment	PTH2R	0.75
169	Breast cancer	Enrichment	GNG3, SHC1	0.67
170	Congenital stationary night blindness	Enrichment	GNB3	0.63
171	Jeune thoracic dystrophy	Enrichment	GRK2	0.60
172	Strabismus	Enrichment	GNB1	0.57
173	Asphyxiating thoracic dystrophy	Enrichment	GRK2	0.56
174	Non-immune hydrops fetalis	Enrichment	CALCRL	0.52
175	Short-rib thoracic dysplasia 1 with or without polydactyly	Enrichment	GRK2	0.50
176	Dystonia	Enrichment	GNB1	0.47
177	Cerebral palsy	Enrichment	GNB1	0.44
178	Epilepsy	Enrichment	TSHR	0.43
179	Nephrotic syndrome	Enrichment	FN1	0.40
180	Thrombocytopenia	Enrichment	SRC	0.37
181	Autosomal dominant non-syndromic intellectual disability	Enrichment	GNB1	0.35
182	Schizophrenia	Enrichment	PDE11A	0.30
183	Primary ciliary dyskinesia	Enrichment	PRKAR1B	0.23
184	Colorectal cancer	Enrichment	SRC	0.20
185	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	ADCY1	0.19
186	Ovarian cancer	Enrichment	TSHR	0.16
187	Congenital nervous system abnormality	Enrichment	GNB5	0.15
188	Nervous system disease	Enrichment	GNB5	0.15
189	Autism spectrum disorder	Enrichment	GNB1	0.14
190	Microcephaly	Enrichment	GNB1	0.12
191	Complex neurodevelopmental disorder	Enrichment	GNB2	0.12
192	Inherited cancer-predisposing syndrome	Enrichment	PRKAR1A	0.10

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

G alpha (s) signalling events

Pathway Network for G alpha (s) signalling events

Member Pathways for G alpha (s) signalling events

Pathways in the G alpha (s) signalling events SuperPath

Associated Genes for G alpha (s) signalling events

Associated Disorders for G alpha (s) signalling events

Disorders associated with G alpha (s) signalling events SuperPath

STRING Interaction Network for G alpha (s) signalling events

Sources for G alpha (s) signalling events