GABA receptor signaling

No Pathway Network information available for GABA receptor signaling

Pathways in the GABA receptor signaling SuperPath

#	Name	Source	Genes
1	GABA receptor signaling	WikiPathways	ABAT ALDH9A1 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 GABBR1 GABBR2 GABRA6 GPHN SLC32A1 SLC6A11 (see all 13) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GABRA6	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha6	Protein Coding	1
2	GABBR2	Gamma-Aminobutyric Acid Type B Receptor Subunit 2	Protein Coding	1
3	GABBR1	Gamma-Aminobutyric Acid Type B Receptor Subunit 1	Protein Coding	1
4	ABAT	4-Aminobutyrate Aminotransferase	Protein Coding	1
5	SLC6A11	Solute Carrier Family 6 Member 11	Protein Coding	1
6	ALDH9A1	Aldehyde Dehydrogenase 9 Family Member A1	Protein Coding	1
7	AP2S1	Adaptor Related Protein Complex 2 Subunit Sigma 1	Protein Coding	1
8	GPHN	Gephyrin	Protein Coding	1
9	AP2B1	Adaptor Related Protein Complex 2 Subunit Beta 1	Protein Coding	1
10	AP2A2	Adaptor Related Protein Complex 2 Subunit Alpha 2	Protein Coding	1
11	AP2A1	Adaptor Related Protein Complex 2 Subunit Alpha 1	Protein Coding	1
12	SLC32A1	Solute Carrier Family 32 Member 1	Protein Coding	1
13	AP2M1	Adaptor Related Protein Complex 2 Subunit Mu 1	Protein Coding	1

Disorders associated with GABA receptor signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hypocalciuric hypercalcemia, familial, type iii	Enrichment	AP2S1	3.02
2	Neurodevelopmental disorder with poor language and loss of hand skills	Enrichment	GABBR2	3.02
3	Developmental and epileptic encephalopathy 59	Enrichment	GABBR2	3.02
4	Gaba aminotransferase deficiency	Enrichment	ABAT	3.02
5	Gaba-transaminase deficiency	Enrichment	ABAT	3.02
6	Generalized epilepsy with febrile seizures plus, type 12	Enrichment	SLC32A1	3.02
7	Neurodevelopmental disorder with language delay and variable cognitive abnormalities	Enrichment	GABBR1	3.02
8	Developmental and epileptic encephalopathy 114	Enrichment	SLC32A1	3.02
9	Hyperekplexia 1	Enrichment	GPHN	2.72
10	Retinal dystrophy, juvenile cataracts, and short stature syndrome	Enrichment	GPHN	2.72
11	Molybdenum cofactor deficiency, type c	Enrichment	GPHN	2.72
12	Intellectual developmental disorder, autosomal dominant 60, with seizures	Enrichment	AP2M1	2.72
13	Leber congenital amaurosis 13	Enrichment	GPHN	2.54
14	Glycosylphosphatidylinositol biosynthesis defect 17	Enrichment	GPHN	2.54
15	Arachnoid cyst	Enrichment	GPHN	2.54
16	Tobacco addiction	Enrichment	GABBR2	2.42
17	Macular dystrophy with or without cone dysfunction	Enrichment	GPHN	2.42
18	Hyperekplexia	Enrichment	GPHN	2.32
19	Anxiety	Enrichment	GPHN	2.24
20	Rett syndrome	Enrichment	GABBR2	2.17
21	Rett syndrome, congenital variant	Enrichment	GABBR2	2.12
22	Neurofibromatosis, type i	Enrichment	GABBR1	2.07
23	Myoclonic-atonic epilepsy	Enrichment	AP2M1	2.07
24	Generalized epilepsy with febrile seizures plus	Enrichment	SLC32A1	1.87
25	Early infantile developmental and epileptic encephalopathy	Enrichment	SLC32A1	1.77
26	Stargardt disease 1	Enrichment	GPHN	1.55
27	Eye disease	Enrichment	GPHN	1.48
28	Cerebral palsy	Enrichment	GPHN	1.43
29	Autosomal dominant non-syndromic intellectual disability	Enrichment	GABBR1	1.33
30	Undetermined early-onset epileptic encephalopathy	Enrichment	GABBR2	1.28
31	Cone-rod dystrophy 2	Enrichment	GPHN	1.20
32	Leber plus disease	Enrichment	GPHN	1.06
33	Retinitis pigmentosa	Enrichment	GPHN	0.73
34	Hereditary retinal dystrophy	Enrichment	GPHN	0.61
35	Fundus dystrophy	Enrichment	GPHN	0.61

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

GABA receptor signaling

Pathway Network for GABA receptor signaling

Member Pathways for GABA receptor signaling

Pathways in the GABA receptor signaling SuperPath

Associated Genes for GABA receptor signaling

Associated Disorders for GABA receptor signaling

Disorders associated with GABA receptor signaling SuperPath

STRING Interaction Network for GABA receptor signaling

Sources for GABA receptor signaling