Galactose metabolism

No Pathway Network information available for Galactose metabolism

Pathways in the Galactose metabolism SuperPath

#	Name	Source	Genes
1	Galactose metabolism	GeneGo (Thomson Reuters)	B4GALT1 B4GALT2 G6PC1 GALE GALK1 GALK2 GALT GCK GLA GYS1 GYS2 HK1 HK2 HK3 LALBA LCT PGM1 PYGB PYGL PYGM (see all 20) (see less)
2	Glycogen metabolism	GeneGo (Thomson Reuters)	AGL GALM GBE1 GCK GPI GYS1 GYS2 HK1 HK2 HK3 PGM1 PYGB PYGL PYGM UGP2 (see all 15) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GCK	Glucokinase	Protein Coding	2
2	GYS1	Glycogen Synthase 1	Protein Coding	2
3	GYS2	Glycogen Synthase 2	Protein Coding	2
4	HK1	Hexokinase 1	Protein Coding	2
5	HK2	Hexokinase 2	Protein Coding	2
6	HK3	Hexokinase 3	Protein Coding	2
7	PGM1	Phosphoglucomutase 1	Protein Coding	2
8	PYGB	Glycogen Phosphorylase B	Protein Coding	2
9	PYGL	Glycogen Phosphorylase L	Protein Coding	2
10	PYGM	Glycogen Phosphorylase, Muscle Associated	Protein Coding	2
11	G6PC1	Glucose-6-Phosphatase Catalytic Subunit 1	Protein Coding	1
12	GALE	UDP-Galactose-4-Epimerase	Protein Coding	1
13	GALK1	Galactokinase 1	Protein Coding	1
14	GALK2	Galactokinase 2	Protein Coding	1
15	GALT	Galactose-1-Phosphate Uridylyltransferase	Protein Coding	1
16	B4GALT1	Beta-1,4-Galactosyltransferase 1	Protein Coding	1
17	GLA	Galactosidase Alpha	Protein Coding	1
18	LALBA	Lactalbumin Alpha	Protein Coding	1
19	LCT	Lactase	Protein Coding	1
20	B4GALT2	Beta-1,4-Galactosyltransferase 2	Protein Coding	1
21	AGL	Amylo-Alpha-1,6-Glucosidase And 4-Alpha-Glucanotransferase	Protein Coding	1
22	GBE1	1,4-Alpha-Glucan Branching Enzyme 1	Protein Coding	1
23	GPI	Glucose-6-Phosphate Isomerase	Protein Coding	1
24	UGP2	UDP-Glucose Pyrophosphorylase 2	Protein Coding	1
25	GALM	Galactose Mutarotase	Protein Coding	1

Disorders associated with Galactose metabolism SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Glycogen storage disease	Enrichment	AGL, GBE1, GYS1, GYS2, PYGM	10.45
2	Glycogen storage disease vi	Enrichment	PYGL	2.96
3	Glycogen storage disease v	Enrichment	PYGM	2.96
4	Anemia, congenital, nonspherocytic hemolytic, 5	Enrichment	HK1	2.96
5	Polyglucosan body neuropathy, adult form	Enrichment	GBE1	2.96
6	Maturity-onset diabetes of the young, type 2	Enrichment	GCK	2.96
7	Retinitis pigmentosa 79	Enrichment	HK1	2.96
8	Galactosemia iv	Enrichment	GALM	2.96
9	Hyperinsulinemic hypoglycemia, familial, 3	Enrichment	GCK	2.96
10	Neuropathy, hereditary motor and sensory, russe type	Enrichment	HK1	2.96
11	Neurodevelopmental disorder with visual defects and brain anomalies	Enrichment	HK1	2.96
12	Anemia, congenital, nonspherocytic hemolytic, 4	Enrichment	GPI	2.96
13	Adult polyglucosan body disease	Enrichment	GBE1	2.96
14	Developmental and epileptic encephalopathy 83	Enrichment	UGP2	2.96
15	Gestational diabetes	Enrichment	GCK	2.96
16	Lactase deficiency, congenital	Enrichment	LCT	2.83
17	Congenital disorder of glycosylation, type iid	Enrichment	B4GALT1	2.83
18	Galactosemia iii	Enrichment	GALE	2.83
19	Combined low ldl and fibrinogen	Enrichment	B4GALT1	2.83
20	Thrombocytopenia 13, syndromic	Enrichment	GALE	2.83
21	Maturity-onset diabetes of the young, type 1	Enrichment	GCK	2.66
22	Glycogen storage disease 0, liver	Enrichment	GYS2	2.66
23	Osteogenesis imperfecta, type xv	Enrichment	GBE1	2.66
24	Diabetes mellitus, permanent neonatal, 1	Enrichment	GCK	2.66
25	Bone marrow failure syndrome 2	Enrichment	GCK	2.66
26	Congenital disorder of glycosylation, type it	Enrichment	PGM1	2.66
27	Glycogen storage disease iii	Enrichment	AGL	2.66
28	Glycogen storage disease 0, muscle	Enrichment	GYS1	2.66
29	Glycogen storage disorder due to hepatic glycogen synthase deficiency	Enrichment	GYS2	2.66
30	Glycogen storage disease due to muscle and heart glycogen synthase deficiency	Enrichment	GYS1	2.66
31	Galactosemia ii	Enrichment	GALK1	2.53
32	Galactosemia i	Enrichment	GALT	2.53
33	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	GALK1	2.53
34	Galactosemia	Enrichment	GALT	2.53
35	Glycogen storage disease iv	Enrichment	GBE1	2.48
36	Nijmegen breakage syndrome	Enrichment	GCK	2.48
37	Cutis laxa, autosomal recessive, type ib	Enrichment	GBE1	2.48
38	Maturity-onset diabetes of the young, type 3	Enrichment	GCK	2.35
39	Glycogen storage disease ia	Enrichment	G6PC1	2.23
40	Hyperinsulinemic hypoglycemia, familial, 1	Enrichment	GCK	2.18
41	Hereditary spherocytosis	Enrichment	GPI	2.18
42	Nonsyndromic genetic hyperinsulinism	Enrichment	GCK	2.18
43	Epidermolysis bullosa simplex 1c, localized	Enrichment	GALK1	2.13
44	Fabry disease	Enrichment	GLA	2.13
45	Hypoglycemia	Enrichment	G6PC1	2.13
46	Hemolytic anemia	Enrichment	GPI	2.11
47	Permanent neonatal diabetes mellitus	Enrichment	GCK	2.05
48	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	GALK1	2.05
49	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	GALK1	2.05
50	Junctional epidermolysis bullosa non-herlitz type	Enrichment	GALK1	2.05
51	Epidermolysis bullosa simplex	Enrichment	GALK1	1.99
52	Diabetes mellitus	Enrichment	GCK	1.92
53	Junctional epidermolysis bullosa	Enrichment	GALK1	1.88
54	Congenital disorder of glycosylation, type in	Enrichment	PGM1	1.73
55	Maturity-onset diabetes of the young	Enrichment	GCK	1.66
56	Fetal akinesia deformation sequence 1	Enrichment	GBE1	1.40
57	Type 2 diabetes mellitus	Enrichment	GCK	1.34
58	Distal arthrogryposis	Enrichment	GBE1	1.34
59	Familial hypertrophic cardiomyopathy	Enrichment	GLA	1.32
60	Nephrotic syndrome	Enrichment	GLA	1.21
61	Hypertrophic cardiomyopathy	Enrichment	GLA	1.21
62	Primary ovarian insufficiency	Enrichment	GALT	1.08
63	Autism spectrum disorder	Enrichment	HK1	0.94
64	Retinitis pigmentosa	Enrichment	HK1	0.68
65	Hereditary retinal dystrophy	Enrichment	HK1	0.56
66	Fundus dystrophy	Enrichment	HK1	0.56

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Galactose metabolism

Pathway Network for Galactose metabolism

Member Pathways for Galactose metabolism

Pathways in the Galactose metabolism SuperPath

Associated Genes for Galactose metabolism

Associated Disorders for Galactose metabolism

Disorders associated with Galactose metabolism SuperPath

STRING Interaction Network for Galactose metabolism

Sources for Galactose metabolism