Gamma-glutamyl cycle for the biosynthesis and degradation of glutathione, including diseases
No Pathway Network information available for Gamma-glutamyl cycle for the biosynthesis and degradation of glutathione, including diseases
Pathways in the Gamma-glutamyl cycle for the biosynthesis and degradation of glutathione, including diseases SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Gamma-glutamyl cycle for the biosynthesis and degradation of glutathione, including diseases | WikiPathways |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | GGCT | Gamma-Glutamylcyclotransferase | Protein Coding | 1 |
| 2 | OPLAH | 5-Oxoprolinase, ATP-Hydrolysing | Protein Coding | 1 |
| 3 | GSS | Glutathione Synthetase | Protein Coding | 1 |
| 4 | GCLC | Glutamate-Cysteine Ligase Catalytic Subunit | Protein Coding | 1 |
| 5 | DPEP1 | Dipeptidase 1 | Protein Coding | 1 |
| 6 | GGT1 | Gamma-Glutamyltransferase 1 | Protein Coding | 1 |
Disorders associated with Gamma-glutamyl cycle for the biosynthesis and degradation of glutathione, including diseases SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Glutathione synthetase deficiency | Enrichment | GSS | 3.35 |
| 2 | Glutathionuria | Enrichment | GGT1 | 3.35 |
| 3 | Anemia, congenital, nonspherocytic hemolytic, 6 | Enrichment | GSS | 3.35 |
| 4 | Anemia, congenital, nonspherocytic hemolytic, 7 | Enrichment | GCLC | 3.35 |
| 5 | 5-oxoprolinase deficiency | Enrichment | OPLAH | 3.35 |
| 6 | Myocardial infarction | Enrichment | GCLC | 2.01 |
| 7 | Cystic fibrosis | Enrichment | GCLC | 1.85 |
