Gemcitabine Pathway, Pharmacokinetics/Pharmacodynamics

No Pathway Network information available for Gemcitabine Pathway, Pharmacokinetics/Pharmacodynamics

#	Name	Source	Genes
1	Gemcitabine Pathway, Pharmacokinetics/Pharmacodynamics	PharmGKB	CDA CMPK1 DCK DCTD NT5C RRM1 RRM2 RRM2B SLC28A1 SLC28A3 SLC29A1 SLC29A2 (see all 12) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SLC28A3	Solute Carrier Family 28 Member 3	Protein Coding	1
2	RRM1	Ribonucleotide Reductase Catalytic Subunit M1	Protein Coding	1
3	RRM2	Ribonucleotide Reductase Regulatory Subunit M2	Protein Coding	1
4	NT5C	5'', 3''-Nucleotidase, Cytosolic	Protein Coding	1
5	CDA	Cytidine Deaminase	Protein Coding	1
6	SLC28A1	Solute Carrier Family 28 Member 1	Protein Coding	1
7	SLC29A2	Solute Carrier Family 29 Member 2	Protein Coding	1
8	DCK	Deoxycytidine Kinase	Protein Coding	1
9	DCTD	DCMP Deaminase	Protein Coding	1
10	SLC29A1	Solute Carrier Family 29 Member 1 (Augustine Blood Group)	Protein Coding	1
11	RRM2B	Ribonucleotide Reductase Regulatory TP53 Inducible Subunit M2B	Protein Coding	1
12	CMPK1	Cytidine/Uridine Monophosphate Kinase 1	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 6	Enrichment	RRM1	3.05
2	Hemolytic disease of the fetus	Enrichment	SLC29A1	3.05
3	Mitochondrial dna depletion syndrome 8b	Enrichment	RRM2B	3.05
4	Uridine-cytidineuria	Enrichment	SLC28A1	3.05
5	Rrm2b mitochondrial dna maintenance defects	Enrichment	RRM2B	3.05
6	Fanconi renotubular syndrome 1	Enrichment	RRM2B	2.75
7	Rod-cone dystrophy, sensorineural deafness, and fanconi-type renal dysfunction	Enrichment	RRM2B	2.75
8	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 5	Enrichment	RRM2B	2.75
9	Mitochondrial dna depletion syndrome 8a	Enrichment	RRM2B	2.75
10	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 2	Enrichment	RRM2B	2.75
11	Idiopathic camptocormia	Enrichment	RRM2B	2.58
12	Kearns-sayre syndrome	Enrichment	RRM2B	2.35
13	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1	Enrichment	RRM2B	2.28
14	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	RRM2B	2.10
15	Sensorineural hearing loss	Enrichment	RRM2B	1.38
16	Mitochondrial disease	Enrichment	RRM2B	1.13
17	Retinitis pigmentosa	Enrichment	RRM2B	0.76

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Gemcitabine Pathway, Pharmacokinetics/Pharmacodynamics