Genes associated with the development of rheumatoid arthritis

No Pathway Network information available for Genes associated with the development of rheumatoid arthritis

Pathways in the Genes associated with the development of rheumatoid arthritis SuperPath

#	Name	Source	Genes
1	Genes associated with the development of rheumatoid arthritis	WikiPathways	BLK CCR6 CD244 CD40 CIITA CTLA4 FCRL3 HLA-DRB1 IL2RA IL6ST IRF5 ITGAV PADI4 PHF19 PTPN22 SLC22A4 STAT4 TRAF1 (see all 18) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CD40	CD40 Molecule	Protein Coding	1
2	TRAF1	TNF Receptor Associated Factor 1	Protein Coding	1
3	STAT4	Signal Transducer And Activator Of Transcription 4	Protein Coding	1
4	SLC22A4	Solute Carrier Family 22 Member 4	Protein Coding	1
5	BLK	BLK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
6	CD244	CD244 Molecule	Protein Coding	1
7	CIITA	Class II Major Histocompatibility Complex Transactivator	Protein Coding	1
8	ITGAV	Integrin Subunit Alpha V	Protein Coding	1
9	IRF5	Interferon Regulatory Factor 5	Protein Coding	1
10	IL6ST	Interleukin 6 Cytokine Family Signal Transducer	Protein Coding	1
11	IL2RA	Interleukin 2 Receptor Subunit Alpha	Protein Coding	1
12	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	Protein Coding	1
13	PTPN22	Protein Tyrosine Phosphatase Non-Receptor Type 22	Protein Coding	1
14	PADI4	Peptidyl Arginine Deiminase 4	Protein Coding	1
15	CTLA4	Cytotoxic T-Lymphocyte Associated Protein 4	Protein Coding	1
16	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	1
17	FCRL3	Fc Receptor Like 3	Protein Coding	1
18	PHF19	PHD Finger Protein 19	Protein Coding	1

Disorders associated with Genes associated with the development of rheumatoid arthritis SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Systemic lupus erythematosus	Enrichment	BLK, CTLA4, HLA-DRB1, IRF5, PTPN22, STAT4	16.00
2	Rheumatoid arthritis	Enrichment	CD244, CIITA, IRF5, SLC22A4	9.55
3	Diffuse cutaneous systemic sclerosis	Enrichment	CCR6, HLA-DRB1, IRF5	7.71
4	Limited scleroderma	Enrichment	CCR6, HLA-DRB1, IRF5	7.41
5	Oligoarticular juvenile idiopathic arthritis	Enrichment	IL2RA, PTPN22, STAT4	7.16
6	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	IL2RA, PTPN22, STAT4	7.16
7	Vogt-koyanagi-harada disease	Enrichment	HLA-DRB1, PTPN22	5.30
8	Temporal arteritis	Enrichment	HLA-DRB1, PTPN22	5.00
9	Granulomatosis with polyangiitis	Enrichment	CTLA4, PTPN22	4.60
10	Type 1 diabetes mellitus 10	Enrichment	IL2RA	2.88
11	Celiac disease 3	Enrichment	CTLA4	2.88
12	Stuve-wiedemann syndrome 2	Enrichment	IL6ST	2.88
13	Hyper-ige syndrome 4a, autosomal dominant, with recurrent infections	Enrichment	IL6ST	2.88
14	Disabling pansclerotic morphea of childhood	Enrichment	STAT4	2.88
15	Type 1 diabetes mellitus 12	Enrichment	CTLA4	2.88
16	Systemic lupus erythematosus 11	Enrichment	STAT4	2.88
17	Pulmonary alveolar proteinosis, acquired	Enrichment	HLA-DRB1	2.88
18	Systemic lupus erythematosus 10	Enrichment	IRF5	2.88
19	Immunodeficiency with hyper-igm, type 3	Enrichment	CD40	2.88
20	Inflammatory bowel disease 14	Enrichment	IRF5	2.88
21	Hyper-ige syndrome 4b, autosomal recessive, with recurrent infections	Enrichment	IL6ST	2.88
22	Immunodeficiency 94 with autoinflammation and dysmorphic facies	Enrichment	IL6ST	2.88
23	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	2.88
24	Hashimoto thyroiditis	Enrichment	CTLA4	2.58
25	Immunodeficiency 41 with lymphoproliferation and autoimmunity	Enrichment	IL2RA	2.58
26	Maturity-onset diabetes of the young, type 11	Enrichment	BLK	2.58
27	Sarcoidosis 1	Enrichment	HLA-DRB1	2.58
28	Bullous pemphigoid	Enrichment	HLA-DRB1	2.58
29	Pediatric multiple sclerosis	Enrichment	HLA-DRB1	2.58
30	Mycosis fungoides	Enrichment	CTLA4	2.40
31	Stuve-wiedemann syndrome 1	Enrichment	IL6ST	2.40
32	Immune dysregulation with autoimmunity, immunodeficiency, and lymphoproliferation	Enrichment	CTLA4	2.40
33	Asparagine synthetase deficiency	Enrichment	CTLA4	2.40
34	Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome	Enrichment	CTLA4	2.40
35	Adult-onset myasthenia gravis	Enrichment	CTLA4	2.40
36	Stüve-wiedemann syndrome	Enrichment	IL6ST	2.40
37	Saczary syndrome	Enrichment	CTLA4	2.40
38	Immunodeficiency, common variable, 1	Enrichment	CTLA4	2.28
39	Pediatric systemic lupus erythematosus	Enrichment	STAT4	2.28
40	Systemic-onset juvenile idiopathic arthritis	Enrichment	HLA-DRB1	2.28
41	Narcolepsy 2	Enrichment	HLA-DRB1	2.18
42	Follicular lymphoma	Enrichment	HLA-DRB1	2.18
43	Narcolepsy 1	Enrichment	HLA-DRB1	1.98
44	Primary biliary cholangitis	Enrichment	IRF5	1.93
45	Mhc class ii deficiency	Enrichment	CIITA	1.93
46	Mhc class ii deficiency 1	Enrichment	CIITA	1.84
47	Multiple sclerosis	Enrichment	HLA-DRB1	1.73
48	Behcet syndrome	Enrichment	STAT4	1.60
49	Maturity-onset diabetes of the young	Enrichment	BLK	1.58
50	Severe covid-19	Enrichment	ITGAV	1.42

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Genes associated with the development of rheumatoid arthritis

Pathway Network for Genes associated with the development of rheumatoid arthritis

Member Pathways for Genes associated with the development of rheumatoid arthritis

Pathways in the Genes associated with the development of rheumatoid arthritis SuperPath

Associated Genes for Genes associated with the development of rheumatoid arthritis

Associated Disorders for Genes associated with the development of rheumatoid arthritis

Disorders associated with Genes associated with the development of rheumatoid arthritis SuperPath

STRING Interaction Network for Genes associated with the development of rheumatoid arthritis

Sources for Genes associated with the development of rheumatoid arthritis