Globo sphingolipid metabolism
Pathways in the Globo sphingolipid metabolism SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Globo sphingolipid metabolism | WikiPathways |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | B3GALNT1 | Beta-1,3-N-Acetylgalactosaminyltransferase 1 (Globoside Blood Group) | Protein Coding | 1 |
| 2 | ST6GAL2 | ST6 Beta-Galactoside Alpha-2,6-Sialyltransferase 2 | Protein Coding | 1 |
| 3 | ST3GAL2 | ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 2 | Protein Coding | 1 |
| 4 | ST6GALNAC1 | ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 1 | Protein Coding | 1 |
| 5 | ST6GALNAC6 | ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 6 | Protein Coding | 1 |
| 6 | ST6GALNAC4 | ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 4 | Protein Coding | 1 |
| 7 | GALNT2 | Polypeptide N-Acetylgalactosaminyltransferase 2 | Protein Coding | 1 |
| 8 | ST6GALNAC3 | ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 3 | Protein Coding | 1 |
| 9 | FUT1 | Fucosyltransferase 1 (H Blood Group) | Protein Coding | 1 |
| 10 | FUT9 | Fucosyltransferase 9 | Protein Coding | 1 |
| 11 | B3GALT5 | Beta-1,3-Galactosyltransferase 5 | Protein Coding | 1 |
| 12 | ST6GALNAC5 | ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 5 | Protein Coding | 1 |
| 13 | ST8SIA1 | ST8 Alpha-N-Acetyl-Neuraminide Alpha-2,8-Sialyltransferase 1 | Protein Coding | 1 |
| 14 | ST3GAL1 | ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 1 | Protein Coding | 1 |
| 15 | ST6GAL1 | ST6 Beta-Galactoside Alpha-2,6-Sialyltransferase 1 | Protein Coding | 1 |
| 16 | A4GALT | Alpha 1,4-Galactosyltransferase (P1PK Blood Group) | Protein Coding | 1 |
| 17 | ABO | ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase | Protein Coding | 1 |
| 18 | GCNT1 | Glucosaminyl (N-Acetyl) Transferase 1 | Protein Coding | 1 |
| 19 | FUT2 | Fucosyltransferase 2 (H Blood Group) | Protein Coding | 1 |
| 20 | ST6GALNAC2 | ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 2 | Protein Coding | 1 |
Disorders associated with Globo sphingolipid metabolism SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Blood group, p1pk system | Enrichment | A4GALT, B3GALNT1 | 5.69 |
| 2 | Bombay phenotype | Enrichment | FUT1, FUT2 | 5.69 |
| 3 | Blood group, globoside system | Enrichment | B3GALNT1 | 2.83 |
| 4 | Congenital disorder of glycosylation, type iit | Enrichment | GALNT2 | 2.83 |
| 5 | Vitamin b12 plasma level quantitative trait locus 1 | Enrichment | FUT2 | 2.53 |
| 6 | Caffey disease | Enrichment | A4GALT | 2.35 |
