Glucocorticoid biosynthesis

No Pathway Network information available for Glucocorticoid biosynthesis

Pathways in the Glucocorticoid biosynthesis SuperPath

#	Name	Source	Genes
1	Glucocorticoid biosynthesis	WikiPathways	AKR1C1 AKR1C2 AKR1C3 AKR1C4 AKR1D1 CBR1 CYP11B1 CYP11B2 CYP21A2 CYP3A4 HSD11B1 HSD11B2 SRD5A1 SRD5A2 (see all 14) (see less)
2	allopregnanolone biosynthesis	PubChem	AKR1C1 AKR1C2 AKR1C3 AKR1C4 SRD5A1 SRD5A2 (see all 6) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AKR1C2	Aldo-Keto Reductase Family 1 Member C2	Protein Coding	2
2	AKR1C1	Aldo-Keto Reductase Family 1 Member C1	Protein Coding	2
3	SRD5A2	Steroid 5 Alpha-Reductase 2	Protein Coding	2
4	SRD5A1	Steroid 5 Alpha-Reductase 1	Protein Coding	2
5	AKR1C4	Aldo-Keto Reductase Family 1 Member C4	Protein Coding	2
6	AKR1C3	Aldo-Keto Reductase Family 1 Member C3	Protein Coding	2
7	HSD11B2	Hydroxysteroid 11-Beta Dehydrogenase 2	Protein Coding	1
8	CYP21A2	Cytochrome P450 Family 21 Subfamily A Member 2	Protein Coding	1
9	AKR1D1	Aldo-Keto Reductase Family 1 Member D1	Protein Coding	1
10	CYP11B1	Cytochrome P450 Family 11 Subfamily B Member 1	Protein Coding	1
11	HSD11B1	Hydroxysteroid 11-Beta Dehydrogenase 1	Protein Coding	1
12	CBR1	Carbonyl Reductase 1	Protein Coding	1
13	CYP3A4	Cytochrome P450 Family 3 Subfamily A Member 4	Protein Coding	1
14	CYP11B2	Cytochrome P450 Family 11 Subfamily B Member 2	Protein Coding	1

Disorders associated with Glucocorticoid biosynthesis SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	46,xy sex reversal 8	Enrichment	AKR1C2, AKR1C4	6.31
2	Hyperaldosteronism, familial, type i	Enrichment	CYP11B1, CYP11B2	4.83
3	Lipoid congenital adrenal hyperplasia	Enrichment	CYP11B1, CYP21A2	4.05
4	46,xy disorder of sex development due to 5-alpha-reductase 2 deficiency	Enrichment	SRD5A2	3.35
5	Xanthinuria, type i	Enrichment	SRD5A2	3.05
6	Cic-rearranged sarcoma	Enrichment	AKR1C2	3.05
7	Bile acid synthesis defect, congenital, 2	Enrichment	AKR1D1	2.99
8	Apparent mineralocorticoid excess	Enrichment	HSD11B2	2.99
9	Vitamin d-dependent rickets, type 3	Enrichment	CYP3A4	2.99
10	Corticosterone methyloxidase type i deficiency	Enrichment	CYP11B2	2.69
11	Corticosterone methyloxidase type ii deficiency	Enrichment	CYP11B2	2.69
12	Congenital bile acid synthesis defect	Enrichment	AKR1D1	2.69
13	Cortisone reductase deficiency 2	Enrichment	HSD11B1	2.69
14	Cortisone reductase deficiency	Enrichment	HSD11B1	2.69
15	Familial hypoaldosteronism	Enrichment	CYP11B2	2.69
16	Early-onset familial hypoaldosteronism	Enrichment	CYP11B2	2.69
17	Pseudovaginal perineoscrotal hypospadias	Enrichment	SRD5A2	2.66
18	Developmental dysplasia of the hip 1	Enrichment	AKR1C1	2.58
19	Adrenal hyperplasia, congenital, due to steroid 11-beta-hydroxylase deficiency	Enrichment	CYP11B1	2.51
20	Deficiency of steroid 11-beta-monooxygenase	Enrichment	CYP11B1	2.51
21	Adrenal hyperplasia, congenital, due to 21-hydroxylase deficiency	Enrichment	CYP21A2	2.21
22	21-hydroxylase-deficient congenital adrenal hyperplasia	Enrichment	CYP21A2	2.21
23	Prostate cancer	Enrichment	SRD5A2	1.89
24	Autism spectrum disorder	Enrichment	SRD5A2	1.33

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Glucocorticoid biosynthesis

Pathway Network for Glucocorticoid biosynthesis

Member Pathways for Glucocorticoid biosynthesis

Pathways in the Glucocorticoid biosynthesis SuperPath

Associated Genes for Glucocorticoid biosynthesis

Associated Disorders for Glucocorticoid biosynthesis

Disorders associated with Glucocorticoid biosynthesis SuperPath

STRING Interaction Network for Glucocorticoid biosynthesis

Sources for Glucocorticoid biosynthesis