Glucocorticoid Pathway (HPA Axis), Pharmacodynamics

No Pathway Network information available for Glucocorticoid Pathway (HPA Axis), Pharmacodynamics

#	Name	Source	Genes
1	Glucocorticoid Pathway (HPA Axis), Pharmacodynamics	PharmGKB	CRH CRHR1 CRHR2 POMC UCN UCN2 UCN3 (see all 7) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	UCN	Urocortin	Protein Coding	1
2	POMC	Proopiomelanocortin	Protein Coding	1
3	CRH	Corticotropin Releasing Hormone	Protein Coding	1
4	CRHR1	Corticotropin Releasing Hormone Receptor 1	Protein Coding	1
5	CRHR2	Corticotropin Releasing Hormone Receptor 2	Protein Coding	1
6	UCN3	Urocortin 3	Protein Coding	1
7	UCN2	Urocortin 2	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Obesity, early-onset, with adrenal insufficiency and red hair	Enrichment	POMC	2.81
2	Mpv17-related mitochondrial dna maintenance defect	Enrichment	UCN	2.81
3	Obesity due to pro-opiomelanocortin deficiency	Enrichment	POMC	2.81
4	Mitochondrial dna depletion syndrome 6	Enrichment	UCN	2.69
5	Charcot-marie-tooth disease, axonal, type 2ee	Enrichment	UCN	2.69
6	Autosomal dominant sleep-related hypermotor epilepsy	Enrichment	CRH	2.44
7	Body mass index quantitative trait locus 11	Enrichment	POMC	1.59

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Glucocorticoid Pathway (HPA Axis), Pharmacodynamics