Glucocorticoid receptor pathway

No Pathway Network information available for Glucocorticoid receptor pathway

Pathways in the Glucocorticoid receptor pathway SuperPath

#	Name	Source	Genes
1	Glucocorticoid receptor pathway	WikiPathways	ABHD2 ACKR3 ADGRF4 AKAP13 ALOX5AP AMIGO2 ANGPTL4 ANKRD1 ARL5B B3GNT5 BHLHE40 BIRC2 BIRC3 CAVIN2 CCL2 CCL20 CDC42EP3 CDKN1C CPEB4 CUL1 DNAJC15 DNER EDN2 ENC1 EPB41L4B ETNK2 FGD4 FGFBP1 GADD45B GPR153 HSP90AA1 IL11 JUN KTN1 LRRC8A MFGE8 MGAM MT1IP NAV3 NFKB2 NR1I2 NR1I3 NR3C1 PDE4B PLK2 PMP2 POU5F1 PPP1R14C PRRG4 PTGES3 PTGS2 RGS2 RXRA S100P SCNN1A SEC14L1 SERPINB9 SERTAD2 SLC19A2 SLC26A2 SNAI2 SPINK13 SPRY1 SRGN STOM TGFBR3 THBD TNFAIP3 TNS4 TSC22D3 ZIC2 (see all 71) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	MGAM	Maltase-Glucoamylase	Protein Coding	1
2	B3GNT5	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 5	Protein Coding	1
3	ETNK2	Ethanolamine Kinase 2	Protein Coding	1
4	NR1I3	Nuclear Receptor Subfamily 1 Group I Member 3	Protein Coding	1
5	NAV3	Neuron Navigator 3	Protein Coding	1
6	NR1I2	Nuclear Receptor Subfamily 1 Group I Member 2	Protein Coding	1
7	BHLHE40	Basic Helix-Loop-Helix Family Member E40	Protein Coding	1
8	ENC1	Ectodermal-Neural Cortex 1	Protein Coding	1
9	CUL1	Cullin 1	Protein Coding	1
10	CAVIN2	Caveolae Associated Protein 2	Protein Coding	1
11	ZIC2	Zic Family Zinc Finger 2	Protein Coding	1
12	TNFAIP3	TNF Alpha Induced Protein 3	Protein Coding	1
13	THBD	Thrombomodulin	Protein Coding	1
14	SNAI2	Snail Family Transcriptional Repressor 2	Protein Coding	1
15	CCL20	C-C Motif Chemokine Ligand 20	Protein Coding	1
16	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	1
17	SCNN1A	Sodium Channel Epithelial 1 Subunit Alpha	Protein Coding	1
18	S100P	S100 Calcium Binding Protein P	Protein Coding	1
19	RXRA	Retinoid X Receptor Alpha	Protein Coding	1
20	RGS2	Regulator Of G Protein Signaling 2	Protein Coding	1
21	PTGS2	Prostaglandin-Endoperoxide Synthase 2	Protein Coding	1
22	ACKR3	Atypical Chemokine Receptor 3	Protein Coding	1
23	LRRC8A	Leucine Rich Repeat Containing 8 VRAC Subunit A	Protein Coding	1
24	SRGN	Serglycin	Protein Coding	1
25	POU5F1	POU Class 5 Homeobox 1	Protein Coding	1
26	SERPINB9	Serpin Family B Member 9	Protein Coding	1
27	PDE4B	Phosphodiesterase 4B	Protein Coding	1
28	ANGPTL4	Angiopoietin Like 4	Protein Coding	1
29	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
30	GADD45B	Growth Arrest And DNA Damage Inducible Beta	Protein Coding	1
31	MFGE8	Milk Fat Globule EGF And Factor V/VIII Domain Containing	Protein Coding	1
32	KTN1	Kinectin 1	Protein Coding	1
33	GPR153	G Protein-Coupled Receptor 153	Protein Coding	1
34	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
35	IL11	Interleukin 11	Protein Coding	1
36	HSP90AA1	Heat Shock Protein 90 Alpha Family Class A Member 1	Protein Coding	1
37	BIRC3	Baculoviral IAP Repeat Containing 3	Protein Coding	1
38	BIRC2	Baculoviral IAP Repeat Containing 2	Protein Coding	1
39	DNAJC15	DnaJ Heat Shock Protein Family (Hsp40) Member C15	Protein Coding	1
40	NR3C1	Nuclear Receptor Subfamily 3 Group C Member 1	Protein Coding	1
41	ANKRD1	Ankyrin Repeat Domain 1	Protein Coding	1
42	ALOX5AP	Arachidonate 5-Lipoxygenase Activating Protein	Protein Coding	1
43	ADGRF4	Adhesion G Protein-Coupled Receptor F4	Protein Coding	1
44	ARL5B	ARF Like GTPase 5B	Protein Coding	1
45	EDN2	Endothelin 2	Protein Coding	1
46	SLC26A2	Solute Carrier Family 26 Member 2	Protein Coding	1
47	TSC22D3	TSC22 Domain Family Member 3	Protein Coding	1
48	FGD4	FYVE, RhoGEF And PH Domain Containing 4	Protein Coding	1
49	AKAP13	A-Kinase Anchoring Protein 13	Protein Coding	1
50	PLK2	Polo Like Kinase 2	Protein Coding	1
51	PTGES3	Prostaglandin E Synthase 3	Protein Coding	1
52	SLC19A2	Solute Carrier Family 19 Member 2	Protein Coding	1
53	CDKN1C	Cyclin Dependent Kinase Inhibitor 1C	Protein Coding	1
54	SPINK13	Serine Peptidase Inhibitor Kazal Type 13	Protein Coding	1
55	FGFBP1	Fibroblast Growth Factor Binding Protein 1	Protein Coding	1
56	SERTAD2	SERTA Domain Containing 2	Protein Coding	1
57	DNER	Delta/Notch Like EGF Repeat Containing	Protein Coding	1
58	TNS4	Tensin 4	Protein Coding	1
59	ABHD2	Abhydrolase Domain Containing 2, Acylglycerol Lipase	Protein Coding	1
60	CDC42EP3	CDC42 Effector Protein 3	Protein Coding	1
61	SPRY1	Sprouty RTK Signaling Antagonist 1	Protein Coding	1
62	PPP1R14C	Protein Phosphatase 1 Regulatory Inhibitor Subunit 14C	Protein Coding	1
63	CPEB4	Cytoplasmic Polyadenylation Element Binding Protein 4	Protein Coding	1
64	PRRG4	Proline Rich And Gla Domain 4	Protein Coding	1
65	TGFBR3	Transforming Growth Factor Beta Receptor 3	Protein Coding	1
66	MT1IP	Metallothionein 1I, Pseudogene	Pseudogene	1
67	SEC14L1	SEC14 Like Lipid Binding 1	Protein Coding	1
68	EPB41L4B	Erythrocyte Membrane Protein Band 4.1 Like 4B	Protein Coding	1
69	PMP2	Peripheral Myelin Protein 2	Protein Coding	1
70	AMIGO2	Adhesion Molecule With Ig Like Domain 2	Protein Coding	1
71	STOM	Stomatin	Protein Coding	1

Disorders associated with Glucocorticoid receptor pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Diastrophic dysplasia	Enrichment	SLC26A2	2.28
2	Atelosteogenesis, type ii	Enrichment	SLC26A2	2.28
3	Hemolytic uremic syndrome, atypical 6	Enrichment	THBD	2.28
4	Bronchiectasis with or without elevated sweat chloride 2	Enrichment	SCNN1A	2.28
5	Epiphyseal dysplasia, multiple, 4	Enrichment	SLC26A2	2.28
6	Glucocorticoid resistance, generalized	Enrichment	NR3C1	2.28
7	Charcot-marie-tooth disease, demyelinating, type 4h	Enrichment	FGD4	2.28
8	Neurodevelopmental disorder with poor or absent speech, dysmorphic facies, and behavioral abnormalities	Enrichment	NAV3	2.28
9	Charcot-marie-tooth disease, demyelinating, type 1g	Enrichment	PMP2	2.28
10	Liddle syndrome 3	Enrichment	SCNN1A	2.28
11	Achondrogenesis, type ib	Enrichment	SLC26A2	2.28
12	Charcot-marie-tooth disease type 4h	Enrichment	FGD4	2.28
13	Charcot-marie-tooth disease type 1g	Enrichment	PMP2	2.28
14	Agammaglobulinemia 5, autosomal dominant	Enrichment	LRRC8A	2.28
15	Thrombophilia due to thrombomodulin defect	Enrichment	THBD	2.28
16	Plasma triglyceride level quantitative trait locus	Enrichment	ANGPTL4	2.28
17	Oculomotor-abducens synkinesis	Enrichment	ACKR3	2.28
18	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	2.28
19	Familial behcet-like autoinflammatory syndrome	Enrichment	TNFAIP3	2.28
20	Intrauterine growth restriction-short stature-early adult-onset diabetes syndrome	Enrichment	CDKN1C	2.28
21	Galactosemia ii	Enrichment	NR3C1	1.98
22	Thiamine-responsive megaloblastic anemia syndrome	Enrichment	SLC19A2	1.98
23	3mc syndrome 2	Enrichment	SLC26A2	1.98
24	Piebald trait	Enrichment	SNAI2	1.98
25	Holoprosencephaly 5	Enrichment	ZIC2	1.98
26	Intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies	Enrichment	CDKN1C	1.98
27	Immunodeficiency, common variable, 10	Enrichment	NFKB2	1.98
28	Autoinflammatory syndrome, familial, behcet-like 1	Enrichment	TNFAIP3	1.98
29	Pseudohypoaldosteronism	Enrichment	SCNN1A	1.98
30	Liddle syndrome 1	Enrichment	SCNN1A	1.81
31	Pseudohypoaldosteronism, type ib1, autosomal recessive	Enrichment	SCNN1A	1.81
32	Immunodeficiency, common variable, 1	Enrichment	NFKB2	1.68
33	Idiopathic bronchiectasis	Enrichment	SCNN1A	1.68
34	Silver-russell syndrome due to a point mutation	Enrichment	CDKN1C	1.68
35	Lymphoma, mucosa-associated lymphoid type	Enrichment	BIRC3	1.59
36	Holoprosencephaly	Enrichment	ZIC2	1.59
37	Familial cerebral saccular aneurysm	Enrichment	TGFBR3	1.59
38	Holoprosencephaly 1	Enrichment	ZIC2	1.51
39	Atypical hemolytic uremic syndrome with complement gene abnormality	Enrichment	THBD	1.51
40	Waardenburg syndrome, type 2e	Enrichment	SNAI2	1.44
41	Common variable immunodeficiency	Enrichment	NFKB2	1.44
42	Childhood-onset schizophrenia	Enrichment	GPR153	1.39
43	Primary hyperaldosteronism	Enrichment	NR3C1	1.34
44	Stroke, ischemic	Enrichment	ALOX5AP	1.29
45	Autosomal non-syndromic agammaglobulinemia	Enrichment	LRRC8A	1.29
46	Osteochondrodysplasia	Enrichment	SLC26A2	1.25
47	Septopreoptic holoprosencephaly	Enrichment	ZIC2	1.12
48	Midline interhemispheric variant of holoprosencephaly	Enrichment	ZIC2	1.12
49	Microform holoprosencephaly	Enrichment	ZIC2	1.09
50	Lobar holoprosencephaly	Enrichment	ZIC2	1.09
51	Alobar holoprosencephaly	Enrichment	ZIC2	1.07
52	Beckwith-wiedemann syndrome	Enrichment	CDKN1C	1.04
53	Human immunodeficiency virus type 1	Enrichment	CCL2	1.04
54	Charcot-marie-tooth disease type 4	Enrichment	FGD4	1.04
55	Semilobar holoprosencephaly	Enrichment	ZIC2	1.04
56	Williams-beuren syndrome	Enrichment	CDKN1C	1.00
57	Ear malformation	Enrichment	SLC19A2	0.93
58	Brugada syndrome	Enrichment	SCNN1A	0.89
59	Connective tissue disease	Enrichment	SLC26A2	0.81
60	Peripheral nervous system disease	Enrichment	PMP2	0.81
61	Neuropathy	Enrichment	PMP2	0.81
62	Systemic lupus erythematosus	Enrichment	TNFAIP3	0.73
63	Sensorineural hearing loss	Enrichment	SLC19A2	0.65
64	Thrombocytopenia	Enrichment	THBD	0.65
65	Familial isolated dilated cardiomyopathy	Enrichment	ANKRD1	0.61
66	Hereditary breast ovarian cancer syndrome	Enrichment	PLK2	0.60
67	Myeloma, multiple	Enrichment	RXRA	0.59
68	Breast cancer	Enrichment	JUN	0.49
69	Congenital nervous system abnormality	Enrichment	ZIC2	0.37
70	Nervous system disease	Enrichment	ZIC2	0.37
71	Microcephaly	Enrichment	ZIC2	0.32

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Glucocorticoid receptor pathway

Pathway Network for Glucocorticoid receptor pathway

Member Pathways for Glucocorticoid receptor pathway

Pathways in the Glucocorticoid receptor pathway SuperPath

Associated Genes for Glucocorticoid receptor pathway

Associated Disorders for Glucocorticoid receptor pathway

Disorders associated with Glucocorticoid receptor pathway SuperPath

STRING Interaction Network for Glucocorticoid receptor pathway

Sources for Glucocorticoid receptor pathway