glutathione-mediated detoxification I
Pathways in the glutathione-mediated detoxification I SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | glutathione-mediated detoxification I | PubChem | |
| 2 | 4-hydroxy-2-nonenal detoxification | PubChem |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | GSTA1 | Glutathione S-Transferase Alpha 1 | Protein Coding | 2 |
| 2 | NAT8 | N-Acetyltransferase 8 (Putative) | Protein Coding | 1 |
| 3 | GSTA2 | Glutathione S-Transferase Alpha 2 | Protein Coding | 1 |
| 4 | GSTZ1 | Glutathione S-Transferase Zeta 1 | Protein Coding | 1 |
| 5 | GGT5 | Gamma-Glutamyltransferase 5 | Protein Coding | 1 |
| 6 | ABCC1 | ATP Binding Cassette Subfamily C Member 1 (ABCC1 Blood Group) | Protein Coding | 1 |
Disorders associated with glutathione-mediated detoxification I SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Deafness, autosomal dominant 77 | Enrichment | ABCC1 | 3.35 |
| 2 | Maleylacetoacetate isomerase deficiency | Enrichment | GSTZ1 | 3.35 |
| 3 | Rare autosomal dominant non-syndromic sensorineural deafness type dfna | Enrichment | ABCC1 | 1.64 |
