Glycerophospholipid biosynthesis

Pathway network for the Glycerophospholipid biosynthesis SuperPath

Sources:

Reactome
PubChem
WikiPathways

Pathways in the Glycerophospholipid biosynthesis SuperPath

#	Name	Source	Genes
1	Glycerophospholipid biosynthesis	Reactome	ABHD3 ABHD4 ACHE ACP6 AGK AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT5 ALPI AWAT2 BCHE CDIPT CDS1 CDS2 CEPT1 CHAT CHKA CHKB CHPT1 CPNE1 CPNE3 CPNE6 CPNE7 CRLS1 CSNK2A1 CSNK2A2 CSNK2B DDHD1 DDHD2 DGAT1 DGAT2 DGAT2L6 ETNK1 ETNK2 ETNPPL GNPAT GPAM GPAT2 GPAT3 GPAT4 GPCPD1 GPD1 GPD1L GPD2 HADHA HADHB LCLAT1 LIPH LIPI LPCAT1 LPCAT2 LPCAT3 LPCAT4 LPGAT1 LPIN1 LPIN2 LPIN3 MBOAT1 MBOAT2 MBOAT7 MFSD2A MGLL MIGA1 MIGA2 OSBPL10 OSBPL5 OSBPL8 PCTP PCYT1A PCYT1B PCYT2 PEMT PGP PGS1 PHOSPHO1 PISD PITPNB PITPNM1 PITPNM2 PITPNM3 PLA1A PLA2G10 PLA2G12A PLA2G15 PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4C PLA2G4D PLA2G4E PLA2G4F PLA2G5 PLA2G6 PLA2R1 PLAAT1 PLAAT2 PLAAT3 PLAAT4 PLAAT5 PLB1 PLBD1 PLD1 PLD2 PLD3 PLD4 PLD6 PNPLA2 PNPLA3 PNPLA8 PTDSS1 PTDSS2 PTPMT1 SELENOI SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5 STARD10 STARD7 TAFAZZIN TMEM86B (see all 129) (see less)
2	Phospholipid metabolism	Reactome	ABHD3 ABHD4 ACHE ACP6 AGK AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT5 ALPI ARF1 ARF3 AWAT2 BCHE BMX CDIPT CDS1 CDS2 CEPT1 CHAT CHKA CHKB CHPT1 CPNE1 CPNE3 CPNE6 CPNE7 CRLS1 CSNK2A1 CSNK2A2 CSNK2B DDHD1 DDHD2 DGAT1 DGAT2 DGAT2L6 ENPP6 ETNK1 ETNK2 ETNPPL FIG4 GDE1 GDPD1 GDPD3 GDPD5 GNPAT GPAM GPAT2 GPAT3 GPAT4 GPCPD1 GPD1 GPD1L GPD2 HADHA HADHB INPP4A INPP4B INPP5D INPP5E INPP5F INPP5J INPP5K INPPL1 LCLAT1 LIPH LIPI LPCAT1 LPCAT2 LPCAT3 LPCAT4 LPGAT1 LPIN1 LPIN2 LPIN3 MBOAT1 MBOAT2 MBOAT7 MFSD2A MGLL MIGA1 MIGA2 MTM1 MTMR1 MTMR10 MTMR12 MTMR14 MTMR2 MTMR3 MTMR4 MTMR6 MTMR7 MTMR8 MTMR9 OCRL OSBPL10 OSBPL5 OSBPL8 PCTP PCYT1A PCYT1B PCYT2 PEMT PGP PGS1 PHOSPHO1 PI4K2A PI4K2B PI4KA PI4KB PIK3C2A PIK3C2B PIK3C2G PIK3C3 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PIK3R6 PIKFYVE PIP4K2A PIP4K2B PIP4K2C PIP4P1 PIP5K1A PIP5K1B PIP5K1C PISD PITPNB PITPNM1 PITPNM2 PITPNM3 PLA1A PLA2G10 PLA2G12A PLA2G15 PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4C PLA2G4D PLA2G4E PLA2G4F PLA2G5 PLA2G6 PLA2R1 PLAAT1 PLAAT2 PLAAT3 PLAAT4 PLAAT5 PLB1 PLBD1 PLD1 PLD2 PLD3 PLD4 PLD6 PLEKHA1 PLEKHA2 PLEKHA3 PLEKHA4 PLEKHA5 PLEKHA6 PLEKHA8 PNPLA2 PNPLA3 PNPLA6 PNPLA7 PNPLA8 PTDSS1 PTDSS2 PTEN PTPMT1 PTPN13 RAB14 RAB4A RAB5A RUFY1 SACM1L SBF1 SBF2 SELENOI SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5 STARD10 STARD7 SYNJ1 SYNJ2 TAFAZZIN TMEM86B TNFAIP8 TNFAIP8L1 TNFAIP8L2 TNFAIP8L3 TPTE TPTE2 VAC14 (see all 212) (see less)
3	Synthesis of PA	Reactome	ACP6 AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT5 ALPI DDHD1 DDHD2 GNPAT GPAM GPAT2 GPAT3 GPAT4 GPD1 GPD1L GPD2 LCLAT1 LIPH LIPI LPCAT1 LPCAT4 MIGA1 MIGA2 PLA2G10 PLA2G12A PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G4A PLA2G4B PLA2G4D PLA2G5 PLA2R1 PLD1 PLD2 PLD6 (see all 39) (see less)
4	CDP-diacylglycerol biosynthesis	PubChem	ABHD5 AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT5 CDS1 CDS2 GPAM GPAT2 GPAT3 GPAT4 LCLAT1 LPCAT3 LPCAT4 MBOAT1 MBOAT2 MBOAT7 (see all 18) (see less)
5	Acyl chain remodelling of PG	Reactome	CRLS1 LPCAT1 LPCAT4 LPGAT1 PLA2G10 PLA2G12A PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4D PLA2G4F PLA2G5 PLA2R1 (see all 18) (see less)
6	Acyl chain remodelling of PI	Reactome	MBOAT7 PLA2G10 PLA2G12A PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G4A PLA2G4C PLA2G4D PLA2G4E PLA2G4F PLA2G5 PLA2R1 PLAAT3 PLBD1 (see all 17) (see less)
7	Kennedy pathway from sphingolipids	WikiPathways	CEPT1 CHKA CHKB CHPT1 ETNK1 ETNK2 PCYT1A PCYT1B PCYT2 PEMT PISD PTDSS1 PTDSS2 SGPL1 (see all 14) (see less)
8	Synthesis of PE	Reactome	CEPT1 CHKA CHKB ETNK1 ETNK2 ETNPPL LPIN1 LPIN2 LPIN3 PCYT2 PHOSPHO1 PISD SELENOI (see all 13) (see less)
9	Hydrolysis of LPC	Reactome	GPCPD1 PLA2G15 PLA2G4A PLA2G4B PLA2G4C PLA2G4D PLA2G4E PLA2G4F PLBD1 (see all 9) (see less)
10	Synthesis of PG	Reactome	CDS2 PGS1 PLD1 PLD2 PLD3 PLD4 PLD6 PTPMT1 (see all 8) (see less)
11	Acyl chain remodeling of DAG and TAG	Reactome	AWAT2 DGAT1 DGAT2 DGAT2L6 MGLL PNPLA2 PNPLA3 (see all 7) (see less)
12	Acyl chain remodeling of CL	Reactome	HADHA HADHB LCLAT1 PLA2G4A PLA2G6 TAFAZZIN (see all 6) (see less)
13	phosphatidylcholine biosynthesis	PubChem	CEPT1 CHKA CHKB CHPT1 PCYT1A PCYT1B (see all 6) (see less)
14	Synthesis of PI	Reactome	CDIPT CDS1 PITPNM1 PITPNM2 PITPNM3
15	CDP-diacylglycerol biosynthesis I	PubChem	AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT5
16	phosphatidylcholine biosynthesis I	PubChem	CEPT1 CHKA PCYT1A
17	glycerol-3-phosphate shuttle	PubChem	GPD1 GPD2
18	Hydrolysis of LPE	Reactome	GPCPD1 PLA2G4C
19	Synthesis of PS	Reactome	PTDSS1 PTDSS2
20	phosphatidylinositol biosynthesis II (eukaryotes)	PubChem	CDIPT
21	phosphatidylserine biosynthesis I	PubChem	PTDSS1

Gene overlap in member pathways for Glycerophospholipid biosynthesis SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PLA2G4A	Phospholipase A2 Group IVA	Protein Coding	7
2	CEPT1	Choline/Ethanolamine Phosphotransferase 1	Protein Coding	6
3	CHKA	Choline Kinase Alpha	Protein Coding	6
4	PLA2G4D	Phospholipase A2 Group IVD	Protein Coding	6
5	PLA2G4B	Phospholipase A2 Group IVB	Protein Coding	5
6	AGPAT1	1-Acylglycerol-3-Phosphate O-Acyltransferase 1	Protein Coding	5
7	AGPAT2	1-Acylglycerol-3-Phosphate O-Acyltransferase 2	Protein Coding	5
8	CHKB	Choline Kinase Beta	Protein Coding	5
9	PLA2R1	Phospholipase A2 Receptor 1	Protein Coding	5
10	LCLAT1	Lysocardiolipin Acyltransferase 1	Protein Coding	5
11	LPCAT4	Lysophosphatidylcholine Acyltransferase 4	Protein Coding	5
12	PLA2G4F	Phospholipase A2 Group IVF	Protein Coding	5
13	PLA2G2D	Phospholipase A2 Group IID	Protein Coding	5
14	PLA2G2E	Phospholipase A2 Group IIE	Protein Coding	5
15	PCYT1A	Phosphate Cytidylyltransferase 1A, Choline	Protein Coding	5
16	PLA2G1B	Phospholipase A2 Group IB	Protein Coding	5
17	PLA2G2A	Phospholipase A2 Group IIA	Protein Coding	5
18	PLA2G5	Phospholipase A2 Group V	Protein Coding	5
19	AGPAT5	1-Acylglycerol-3-Phosphate O-Acyltransferase 5	Protein Coding	5
20	AGPAT3	1-Acylglycerol-3-Phosphate O-Acyltransferase 3	Protein Coding	5
21	AGPAT4	1-Acylglycerol-3-Phosphate O-Acyltransferase 4	Protein Coding	5
22	PLA2G2F	Phospholipase A2 Group IIF	Protein Coding	5
23	PLA2G12A	Phospholipase A2 Group XIIA	Protein Coding	5
24	PLA2G10	Phospholipase A2 Group X	Protein Coding	5
25	PLA2G4C	Phospholipase A2 Group IVC	Protein Coding	5
26	PTDSS1	Phosphatidylserine Synthase 1	Protein Coding	5
27	CDS1	CDP-Diacylglycerol Synthase 1	Protein Coding	4
28	CDIPT	CDP-Diacylglycerol--Inositol 3-Phosphatidyltransferase	Protein Coding	4
29	PLA2G4E	Phospholipase A2 Group IVE	Protein Coding	4
30	GPAT4	Glycerol-3-Phosphate Acyltransferase 4	Protein Coding	4
31	GPAT2	Glycerol-3-Phosphate Acyltransferase 2, Mitochondrial	Protein Coding	4
32	PLD6	Phospholipase D Family Member 6	Protein Coding	4
33	PISD	Phosphatidylserine Decarboxylase	Protein Coding	4
34	GPD1	Glycerol-3-Phosphate Dehydrogenase 1	Protein Coding	4
35	GPD2	Glycerol-3-Phosphate Dehydrogenase 2	Protein Coding	4
36	PLD1	Phospholipase D1	Protein Coding	4
37	PLD2	Phospholipase D2	Protein Coding	4
38	ETNK2	Ethanolamine Kinase 2	Protein Coding	4
39	ETNK1	Ethanolamine Kinase 1	Protein Coding	4
40	GPCPD1	Glycerophosphocholine Phosphodiesterase 1	Protein Coding	4
41	CHPT1	Choline Phosphotransferase 1	Protein Coding	4
42	GPAM	Glycerol-3-Phosphate Acyltransferase, Mitochondrial	Protein Coding	4
43	PCYT2	Phosphate Cytidylyltransferase 2, Ethanolamine	Protein Coding	4
44	MBOAT7	Membrane Bound Acylglycerophosphatidylinositol O-Acyltransferase MBOAT7	Protein Coding	4
45	PLBD1	Phospholipase B Domain Containing 1	Protein Coding	4
46	LPCAT1	Lysophosphatidylcholine Acyltransferase 1	Protein Coding	4
47	PTDSS2	Phosphatidylserine Synthase 2	Protein Coding	4
48	GPAT3	Glycerol-3-Phosphate Acyltransferase 3	Protein Coding	4
49	CDS2	CDP-Diacylglycerol Synthase 2	Protein Coding	4
50	PCYT1B	Phosphate Cytidylyltransferase 1B, Choline	Protein Coding	4
51	LPCAT3	Lysophosphatidylcholine Acyltransferase 3	Protein Coding	3
52	PEMT	Phosphatidylethanolamine N-Methyltransferase	Protein Coding	3
53	PLAAT3	Phospholipase A And Acyltransferase 3	Protein Coding	3
54	MGLL	Monoglyceride Lipase	Protein Coding	3
55	PTPMT1	Protein Tyrosine Phosphatase Mitochondrial 1	Protein Coding	3
56	PLD4	Phospholipase D Family Member 4	Protein Coding	3
57	MBOAT2	Membrane Bound Glycerophospholipid O-Acyltransferase 2	Protein Coding	3
58	LIPI	Lipase I	Protein Coding	3
59	MBOAT1	Membrane Bound Glycerophospholipid O-Acyltransferase 1	Protein Coding	3
60	AWAT2	Acyl-CoA Wax Alcohol Acyltransferase 2	Protein Coding	3
61	PHOSPHO1	Phosphoethanolamine/Phosphocholine Phosphatase 1	Protein Coding	3
62	LIPH	Lipase H	Protein Coding	3
63	GPD1L	Glycerol-3-Phosphate Dehydrogenase 1 Like	Protein Coding	3
64	LPIN1	Lipin 1	Protein Coding	3
65	DDHD2	DDHD Domain Containing 2	Protein Coding	3
66	PLD3	Phospholipase D Family Member 3	Protein Coding	3
67	PLA2G15	Phospholipase A2 Group XV	Protein Coding	3
68	ALPI	Alkaline Phosphatase, Intestinal	Protein Coding	3
69	HADHA	Hydroxyacyl-CoA Dehydrogenase Trifunctional Multienzyme Complex Subunit Alpha	Protein Coding	3
70	HADHB	Hydroxyacyl-CoA Dehydrogenase Trifunctional Multienzyme Complex Subunit Beta	Protein Coding	3
71	DGAT2L6	Diacylglycerol O-Acyltransferase 2 Like 6	Protein Coding	3
72	MIGA1	Mitoguardin 1	Protein Coding	3
73	PLA2G3	Phospholipase A2 Group III	Protein Coding	3
74	ACP6	Acid Phosphatase 6, Lysophosphatidic	Protein Coding	3
75	CRLS1	Cardiolipin Synthase 1	Protein Coding	3
76	PNPLA2	Patatin Like Domain 2, Triacylglycerol Lipase	Protein Coding	3
77	PITPNM2	Phosphatidylinositol Transfer Protein Membrane Associated 2	Protein Coding	3
78	ETNPPL	Ethanolamine-Phosphate Phospho-Lyase	Protein Coding	3
79	LPIN3	Lipin 3	Protein Coding	3
80	TAFAZZIN	Tafazzin, Phospholipid-Lysophospholipid Transacylase	Protein Coding	3
81	PNPLA3	Patatin Like Domain 3, 1-Acylglycerol-3-Phosphate O-Acyltransferase	Protein Coding	3
82	DDHD1	DDHD Domain Containing 1	Protein Coding	3
83	PITPNM3	PITPNM Family Member 3	Protein Coding	3
84	PLA2G6	Phospholipase A2 Group VI	Protein Coding	3
85	GNPAT	Glyceronephosphate O-Acyltransferase	Protein Coding	3
86	DGAT2	Diacylglycerol O-Acyltransferase 2	Protein Coding	3
87	MIGA2	Mitoguardin 2	Protein Coding	3
88	SELENOI	Selenoprotein I	Protein Coding	3
89	DGAT1	Diacylglycerol O-Acyltransferase 1	Protein Coding	3
90	PGS1	Phosphatidylglycerophosphate Synthase 1	Protein Coding	3
91	PITPNM1	Phosphatidylinositol Transfer Protein Membrane Associated 1	Protein Coding	3
92	LPIN2	Lipin 2	Protein Coding	3
93	LPGAT1	Lysophosphatidylglycerol Acyltransferase 1	Protein Coding	3
94	STARD10	StAR Related Lipid Transfer Domain Containing 10	Protein Coding	2
95	CHAT	Choline O-Acetyltransferase	Protein Coding	2
96	OSBPL5	Oxysterol Binding Protein Like 5	Protein Coding	2
97	OSBPL8	Oxysterol Binding Protein Like 8	Protein Coding	2
98	OSBPL10	Oxysterol Binding Protein Like 10	Protein Coding	2
99	PLAAT5	Phospholipase A And Acyltransferase 5	Protein Coding	2
100	SLC44A3	Solute Carrier Family 44 Member 3	Protein Coding	2
101	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	2
102	CSNK2A2	Casein Kinase 2 Alpha 2	Protein Coding	2
103	CSNK2B	Casein Kinase 2 Beta	Protein Coding	2
104	PLB1	Phospholipase B1	Protein Coding	2
105	ABHD3	Abhydrolase Domain Containing 3, Phospholipase	Protein Coding	2
106	SLC44A5	Solute Carrier Family 44 Member 5	Protein Coding	2
107	SLC44A1	Solute Carrier Family 44 Member 1	Protein Coding	2
108	PITPNB	Phosphatidylinositol Transfer Protein Beta	Protein Coding	2
109	TMEM86B	Transmembrane Protein 86B	Protein Coding	2
110	CPNE7	Copine 7	Protein Coding	2
111	PGP	Phosphoglycolate Phosphatase	Protein Coding	2
112	ACHE	Acetylcholinesterase (Yt Blood Group)	Protein Coding	2
113	PNPLA8	Patatin Like Domain 8, Phospholipase A2	Protein Coding	2
114	PLA1A	Phospholipase A1 Member A	Protein Coding	2
115	LPCAT2	Lysophosphatidylcholine Acyltransferase 2	Protein Coding	2
116	PLAAT2	Phospholipase A And Acyltransferase 2	Protein Coding	2
117	AGK	Acylglycerol Kinase	Protein Coding	2
118	STARD7	StAR Related Lipid Transfer Domain Containing 7	Protein Coding	2
119	PLAAT1	Phospholipase A And Acyltransferase 1	Protein Coding	2
120	SLC44A2	Solute Carrier Family 44 Member 2 (CTL2 Blood Group)	Protein Coding	2
121	PCTP	Phosphatidylcholine Transfer Protein	Protein Coding	2
122	BCHE	Butyrylcholinesterase	Protein Coding	2
123	PLAAT4	Phospholipase A And Acyltransferase 4	Protein Coding	2
124	ABHD4	Abhydrolase Domain Containing 4, N-Acyl Phospholipase B	Protein Coding	2
125	SLC44A4	Solute Carrier Family 44 Member 4	Protein Coding	2
126	MFSD2A	MFSD2 Lysolipid Transporter A, Lysophospholipid	Protein Coding	2
127	CPNE3	Copine 3	Protein Coding	2
128	CPNE1	Copine 1	Protein Coding	2
129	CPNE6	Copine 6	Protein Coding	2
130	PNPLA6	Patatin Like Domain 6, Lysophospholipase	Protein Coding	1
131	TNFAIP8L1	TNF Alpha Induced Protein 8 Like 1	Protein Coding	1
132	ENPP6	Ectonucleotide Pyrophosphatase/Phosphodiesterase 6	Protein Coding	1
133	PIK3R6	Phosphoinositide-3-Kinase Regulatory Subunit 6	Protein Coding	1
134	PIKFYVE	Phosphoinositide Kinase, FYVE-Type Zinc Finger Containing	Protein Coding	1
135	PLEKHA6	Pleckstrin Homology Domain Containing A6	Protein Coding	1
136	INPP5F	Inositol Polyphosphate-5-Phosphatase F	Protein Coding	1
137	SACM1L	SAC1 Like Phosphatidylinositide Phosphatase	Protein Coding	1
138	PIP5K1C	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Gamma	Protein Coding	1
139	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	1
140	TNFAIP8	TNF Alpha Induced Protein 8	Protein Coding	1
141	INPP5J	Inositol Polyphosphate-5-Phosphatase J	Protein Coding	1
142	GDPD1	Glycerophosphodiester Phosphodiesterase Domain Containing 1	Protein Coding	1
143	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	1
144	INPP4A	Inositol Polyphosphate-4-Phosphatase Type I A	Protein Coding	1
145	INPP5D	Inositol Polyphosphate-5-Phosphatase D	Protein Coding	1
146	INPPL1	Inositol Polyphosphate Phosphatase Like 1	Protein Coding	1
147	ARF1	ARF GTPase 1	Protein Coding	1
148	PNPLA7	Patatin Like Domain 7, Lysophospholipase	Protein Coding	1
149	ARF3	ARF GTPase 3	Protein Coding	1
150	TNFAIP8L3	TNF Alpha Induced Protein 8 Like 3	Protein Coding	1
151	MTM1	Myotubularin 1	Protein Coding	1
152	OCRL	OCRL Inositol Polyphosphate-5-Phosphatase	Protein Coding	1
153	RAB14	RAB14, Member RAS Oncogene Family	Protein Coding	1
154	GDE1	Glycerophosphodiester Phosphodiesterase 1	Protein Coding	1
155	INPP5K	Inositol Polyphosphate-5-Phosphatase K	Protein Coding	1
156	PIK3C2A	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha	Protein Coding	1
157	PIK3C2B	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Beta	Protein Coding	1
158	PIK3C2G	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Gamma	Protein Coding	1
159	PIK3C3	Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3	Protein Coding	1
160	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
161	PIK3CB	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta	Protein Coding	1
162	PIK3CD	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta	Protein Coding	1
163	PIK3CG	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma	Protein Coding	1
164	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
165	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	1
166	PI4KA	Phosphatidylinositol 4-Kinase Alpha	Protein Coding	1
167	PI4KB	Phosphatidylinositol 4-Kinase Beta	Protein Coding	1
168	PIP4K2A	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Alpha	Protein Coding	1
169	PLEKHA5	Pleckstrin Homology Domain Containing A5	Protein Coding	1
170	MTMR12	Myotubularin Related Protein 12	Protein Coding	1
171	MTMR10	Myotubularin Related Protein 10	Protein Coding	1
172	PI4K2B	Phosphatidylinositol 4-Kinase Type 2 Beta	Protein Coding	1
173	PI4K2A	Phosphatidylinositol 4-Kinase Type 2 Alpha	Protein Coding	1
174	MTMR8	Myotubularin Related Protein 8	Protein Coding	1
175	VAC14	VAC14 Component Of PIKFYVE Complex	Protein Coding	1
176	INPP5E	Inositol Polyphosphate-5-Phosphatase E	Protein Coding	1
177	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
178	PLEKHA4	Pleckstrin Homology Domain Containing A4	Protein Coding	1
179	PTPN13	Protein Tyrosine Phosphatase Non-Receptor Type 13	Protein Coding	1
180	RAB4A	RAB4A, Member RAS Oncogene Family	Protein Coding	1
181	RAB5A	RAB5A, Member RAS Oncogene Family	Protein Coding	1
182	PLEKHA1	Pleckstrin Homology Domain Containing A1	Protein Coding	1
183	PLEKHA2	Pleckstrin Homology Domain Containing A2	Protein Coding	1
184	SBF1	SET Binding Factor 1	Protein Coding	1
185	MTMR14	Myotubularin Related Protein 14	Protein Coding	1
186	PLEKHA3	Pleckstrin Homology Domain Containing A3	Protein Coding	1
187	BMX	BMX Non-Receptor Tyrosine Kinase	Protein Coding	1
188	MTMR9	Myotubularin Related Protein 9	Protein Coding	1
189	TPTE	Transmembrane Phosphatase With Tensin Homology	Protein Coding	1
190	GDPD3	Glycerophosphodiester Phosphodiesterase Domain Containing 3	Protein Coding	1
191	TNFAIP8L2	TNF Alpha Induced Protein 8 Like 2	Protein Coding	1
192	PIP4K2C	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Gamma	Protein Coding	1
193	RUFY1	RUN And FYVE Domain Containing 1	Protein Coding	1
194	GDPD5	Glycerophosphodiester Phosphodiesterase Domain Containing 5	Protein Coding	1
195	SBF2	SET Binding Factor 2	Protein Coding	1
196	PIP5K1A	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Alpha	Protein Coding	1
197	PIP5K1B	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Beta	Protein Coding	1
198	PIP4K2B	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Beta	Protein Coding	1
199	PLEKHA8	Pleckstrin Homology Domain Containing A8	Protein Coding	1
200	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	1
201	MTMR1	Myotubularin Related Protein 1	Protein Coding	1
202	INPP4B	Inositol Polyphosphate-4-Phosphatase Type II B	Protein Coding	1
203	SYNJ1	Synaptojanin 1	Protein Coding	1
204	SYNJ2	Synaptojanin 2	Protein Coding	1
205	MTMR3	Myotubularin Related Protein 3	Protein Coding	1
206	MTMR2	Myotubularin Related Protein 2	Protein Coding	1
207	PIP4P1	Phosphatidylinositol-4,5-Bisphosphate 4-Phosphatase 1	Protein Coding	1
208	MTMR6	Myotubularin Related Protein 6	Protein Coding	1
209	MTMR7	Myotubularin Related Protein 7	Protein Coding	1
210	MTMR4	Myotubularin Related Protein 4	Protein Coding	1
211	TPTE2	Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2	Protein Coding	1
212	FIG4	FIG4 Phosphoinositide 5-Phosphatase	Protein Coding	1
213	ABHD5	Abhydrolase Domain Containing 5, Lysophosphatidic Acid Acyltransferase	Protein Coding	1
214	SGPL1	Sphingosine-1-Phosphate Lyase 1	Protein Coding	1

Disorders associated with Glycerophospholipid biosynthesis SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Mitochondrial trifunctional protein deficiency 1	Enrichment	HADHA, HADHB	6.31
2	Mitochondrial trifunctional protein deficiency	Enrichment	HADHA, HADHB	6.31
3	Charcot-marie-tooth disease type 4	Enrichment	FIG4, MTMR2, PLD3, SBF1, SBF2	5.19
4	Lenz-majewski hyperostotic dwarfism	Enrichment	PTDSS1	4.13
5	Hypertriglyceridemia, transient infantile	Enrichment	GPD1	3.83
6	Neurodevelopmental disorder with microcephaly, movement abnormalities, and seizures	Enrichment	CHKA	3.66
7	Yunis-varon syndrome	Enrichment	FIG4, VAC14	3.61
8	Transient infantile hypertriglyceridemia and hepatosteatosis	Enrichment	GPD1	3.53
9	Cone-rod dystrophy 5	Enrichment	PITPNM3	3.43
10	Lipodystrophy, congenital generalized, type 1	Enrichment	AGPAT2	3.43
11	Spondylometaphyseal dysplasia with cone-rod dystrophy	Enrichment	PCYT1A	3.35
12	Lipodystrophy, congenital generalized, type 5	Enrichment	PCYT1A	3.35
13	Osteopetrosis and infantile neuroaxonal dystrophy	Enrichment	PLA2G6	3.35
14	Neurodegeneration with brain iron accumulation 2a	Enrichment	PLA2G6	3.35
15	Parkinson disease 14, autosomal recessive	Enrichment	PLA2G6	3.35
16	Neurodegeneration with brain iron accumulation 2b	Enrichment	PLA2G6	3.35
17	Cytosolic phospholipase-a2 alpha deficiency associated bleeding disorder	Enrichment	PLA2G4A	3.35
18	Gastrointestinal ulceration, recurrent, with dysfunctional platelets	Enrichment	PLA2G4A	3.35
19	Mitochondrial trifunctional protein deficiency 2	Enrichment	HADHB	3.35
20	Acute fatty liver of pregnancy	Enrichment	HADHA	3.35
21	Cryptogenic multifocal ulcerous stenosing enteritis	Enrichment	PLA2G4A	3.35
22	Proximal myopathy with focal depletion of mitochondria	Enrichment	CHKB	3.35
23	Autosomal dominant charcot-marie-tooth disease type 2 due to dgat2 mutation	Enrichment	DGAT2	3.29
24	Primary triglyceride deposit cardiomyovasculopathy	Enrichment	PNPLA2	3.29
25	Cardiac valvular dysplasia 1	Enrichment	PLD1	3.23
26	Systemic lupus erythematosus 18	Enrichment	PLD4	3.23
27	Neurodevelopmental disorder with ataxia and brain abnormalities	Enrichment	PTPMT1	3.23
28	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	3.14
29	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3CD, PIK3R1	3.14
30	Immunodeficiency 14	Enrichment	PIK3CD, PIK3R1	3.14
31	Infantile osteopetrosis with neuroaxonal dysplasia	Enrichment	PLA2G6	3.05
32	Majeed syndrome	Enrichment	LPIN2	3.02
33	Spastic paraplegia 81, autosomal recessive	Enrichment	SELENOI	3.02
34	Neutral lipid storage disease with myopathy	Enrichment	PNPLA2	2.99
35	Reni syndrome	Enrichment	SGPL1	2.99
36	Charcot-marie-tooth disease, demyelinating, type 4f	Enrichment	PLD3	2.93
37	Spinocerebellar ataxia 46	Enrichment	PLD3	2.93
38	Charcot-marie-tooth disease type 4f	Enrichment	PLD3	2.93
39	Fleck retina, familial benign	Enrichment	PLA2G5	2.90
40	Intellectual developmental disorder, autosomal recessive 57	Enrichment	MBOAT7	2.90
41	Lipodystrophy, familial partial, type 9	Enrichment	PLAAT3	2.90
42	Familial benign flecked retina	Enrichment	PLA2G5	2.90
43	Barth syndrome	Enrichment	TAFAZZIN	2.88
44	Long-chain 3-hydroxyacyl-coa dehydrogenase deficiency	Enrichment	HADHA	2.88
45	Combined oxidative phosphorylation deficiency 57	Enrichment	CRLS1	2.88
46	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA, PIK3R2	2.85
47	Congenital generalized lipodystrophy	Enrichment	AGPAT2	2.83
48	Muscular dystrophy, congenital, megaconial type	Enrichment	CHKB	2.75
49	Spastic paraplegia 82, autosomal recessive	Enrichment	PCYT2	2.72
50	Liberfarb syndrome	Enrichment	PISD	2.72
51	Diarrhea 7, protein-losing enteropathy type	Enrichment	DGAT1	2.69
52	Hemimegalencephaly	Enrichment	PIK3CA, PTEN	2.63
53	Congenital diarrhea 7 with exudative enteropathy	Enrichment	DGAT1	2.59
54	Chanarin-dorfman syndrome	Enrichment	ABHD5	2.58
55	Myoglobinuria, acute recurrent, autosomal recessive	Enrichment	LPIN1	2.54
56	Rhizomelic chondrodysplasia punctata, type 2	Enrichment	GNPAT	2.54
57	Brugada syndrome 2	Enrichment	GPD1L	2.54
58	Hypotrichosis 7	Enrichment	LIPH	2.54
59	Spastic paraplegia 28, autosomal recessive	Enrichment	DDHD1	2.54
60	Spastic paraplegia 54, autosomal recessive	Enrichment	DDHD2	2.54
61	Alpi-related inflammatory bowel disease	Enrichment	ALPI	2.54
62	Diarrhea	Enrichment	DGAT1	2.51
63	Cowden syndrome 1	Enrichment	PIK3CA, PTEN	2.46
64	Charcot-marie-tooth disease	Enrichment	FIG4, PLD3, SBF1, SBF2	2.43
65	Late-onset retinal degeneration	Enrichment	PLA2G5	2.43
66	Hereditary recurrent myoglobinuria	Enrichment	LPIN1	2.42
67	Male infertility	Enrichment	GPAT2, PLD6	2.37
68	Neurodegeneration with brain iron accumulation	Enrichment	PLA2G6	2.35
69	Type 2 diabetes mellitus	Enrichment	GPD2	2.21
70	Hereditary spastic paraplegia	Enrichment	DDHD1, DDHD2	2.19
71	Arteriovenous malformations of the brain	Enrichment	PITPNM3	2.16
72	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	PLA2G6	2.15
73	Cowden syndrome	Enrichment	PIK3CA, PTEN	2.09
74	Cone dystrophy	Enrichment	PITPNM3	2.05
75	Apnea, central sleep	Enrichment	CHAT	2.02
76	Mitochondrial myopathy with lactic acidosis	Enrichment	PNPLA8	2.02
77	Epilepsy, familial adult myoclonic, 2	Enrichment	STARD7	2.02
78	Yt blood group antigen	Enrichment	ACHE	2.02
79	Cataract 38	Enrichment	AGK	2.02
80	Neurodevelopmental disorder with progressive microcephaly, spasticity, and brain imaging abnormalities	Enrichment	MFSD2A	2.02
81	Butyrylcholinesterase deficiency	Enrichment	BCHE	2.02
82	Okur-chung neurodevelopmental syndrome	Enrichment	CSNK2A1	2.02
83	Neurodegeneration, childhood-onset, with ataxia, tremor, optic atrophy, and cognitive decline	Enrichment	SLC44A1	2.02
84	Deafness, autosomal dominant 72	Enrichment	SLC44A4	2.02
85	Aspiration pneumonia	Enrichment	CHAT	2.02
86	Craniodigital syndrome and intellectual disability syndrome	Enrichment	CSNK2B	2.02
87	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3CD, PIK3R1	2.00
88	Muscular dystrophy	Enrichment	CHKB	1.98
89	Generalized epilepsy	Enrichment	DDHD2	1.94
90	Rhizomelic chondrodysplasia punctata	Enrichment	GNPAT	1.94
91	Pectus excavatum	Enrichment	ARF3, INPP4A	1.91
92	Familial colorectal cancer	Enrichment	PLA2G2A	1.90
93	Autosomal recessive non-syndromic intellectual disability	Enrichment	CHKA	1.89
94	Familial woolly hair syndrome	Enrichment	LIPH	1.84
95	Meningioma	Enrichment	PIK3CA, PTEN	1.84
96	Left ventricular noncompaction	Enrichment	TAFAZZIN	1.81
97	Macrodactyly	Enrichment	PIK3CA	1.81
98	Corneal dystrophy, fleck	Enrichment	PIKFYVE	1.81
99	Laurence-moon syndrome	Enrichment	PNPLA6	1.81
100	Vacterl association with hydrocephalus	Enrichment	PTEN	1.81
101	Oliver-mcfarlane syndrome	Enrichment	PNPLA6	1.81
102	Polymicrogyria, bilateral temporooccipital	Enrichment	FIG4	1.81
103	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	1.81
104	Cowden syndrome 5	Enrichment	PIK3CA	1.81
105	Boucher-neuhauser syndrome	Enrichment	PNPLA6	1.81
106	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	1.81
107	Developmental and epileptic encephalopathy 53	Enrichment	SYNJ1	1.81
108	Cerebral cavernous malformations 4	Enrichment	PIK3CA	1.81
109	Short syndrome	Enrichment	PIK3R1	1.81
110	Charcot-marie-tooth disease type 4b1	Enrichment	MTMR2	1.81
111	Oculoskeletodental syndrome	Enrichment	PIK3C2A	1.81
112	Neurodevelopmental disorder with growth impairment, quadriparesis, and poor or absent speech	Enrichment	INPP4A	1.81
113	Lowe oculocerebrorenal syndrome	Enrichment	OCRL	1.81
114	Charcot-marie-tooth disease, demyelinating, type 4b1	Enrichment	MTMR2	1.81
115	Amyotrophic lateral sclerosis 11	Enrichment	FIG4	1.81
116	Papillary tumor of the pineal region	Enrichment	PTEN	1.81
117	Charcot-marie-tooth disease, demyelinating, type 4j	Enrichment	FIG4	1.81
118	Hemifacial myohyperplasia	Enrichment	PIK3CA	1.81
119	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	1.81
120	Impaired intellectual development, truncal obesity, retinal dystrophy, and micropenis syndrome	Enrichment	INPP5E	1.81
121	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	1.81
122	Immunodeficiency 14b, autosomal recessive	Enrichment	PIK3CD	1.81
123	Spastic paraplegia 39, autosomal recessive	Enrichment	PNPLA6	1.81
124	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	1.81
125	Immunodeficiency 97 with autoinflammation	Enrichment	PIK3CG	1.81
126	Glioma susceptibility 2	Enrichment	PTEN	1.81
127	Muscular dystrophy, congenital, with cataracts and impaired intellectual development	Enrichment	INPP5K	1.81
128	Spastic paraplegia 84, autosomal recessive	Enrichment	PI4KA	1.81
129	Charcot-marie-tooth disease type 4j	Enrichment	FIG4	1.81
130	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	1.81
131	Deafness, autosomal dominant 87	Enrichment	PI4KB	1.81
132	Hypospadias	Enrichment	PIK3CA	1.81
133	Rare venous malformation	Enrichment	PIK3CA	1.81
134	Diaphragmatic eventration	Enrichment	PIK3CA	1.81
135	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	1.81
136	Rare combined vascular malformation	Enrichment	PIK3CA	1.81
137	Gastrointestinal defects and immunodeficiency syndrome 2	Enrichment	PI4KA	1.81
138	Cavernous lymphangioma	Enrichment	PIK3CA	1.81
139	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	1.81
140	Oculocerebrodental syndrome	Enrichment	PIK3C2A	1.81
141	Qualitative or quantitative defects of myotubularin	Enrichment	MTM1	1.81
142	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	1.81
143	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	1.81
144	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	1.81
145	Macrodactyly of toe	Enrichment	PIK3CA	1.81
146	Pi4ka-related disorder	Enrichment	PI4KA	1.81
147	Bardet-biedl syndrome 10	Enrichment	OSBPL8	1.72
148	Poirier-bienvenu neurodevelopmental syndrome	Enrichment	CSNK2B	1.72
149	Schizophrenia 19	Enrichment	CPNE1	1.72
150	Myasthenic syndrome, congenital, 21, presynaptic	Enrichment	CHAT	1.72
151	Leber plus disease	Enrichment	PCYT1A	1.68
152	Autoinflammatory disease	Enrichment	LPIN2	1.64
153	Spastic ataxia	Enrichment	PLA2G6	1.63
154	Familial isolated dilated cardiomyopathy	Enrichment	TAFAZZIN	1.63
155	Cone-rod dystrophy 2	Enrichment	PITPNM3	1.61
156	Hypotrichosis simplex	Enrichment	LIPH	1.59
157	Microcephaly	Enrichment	CHKA	1.57
158	Prognathism, mandibular	Enrichment	CSNK2B	1.55
159	Sengers syndrome	Enrichment	AGK	1.55
160	Myasthenic syndrome, congenital, 6, presynaptic	Enrichment	CHAT	1.55
161	Multicentric osteolysis, nodulosis, and arthropathy	Enrichment	LPCAT2	1.55
162	Bronchopulmonary dysplasia	Enrichment	CHAT	1.55
163	Gordon holmes syndrome	Enrichment	PNPLA6	1.51
164	Schneckenbecken dysplasia	Enrichment	INPPL1	1.51
165	Lethal congenital contracture syndrome 3	Enrichment	PIP5K1C	1.51
166	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	1.51
167	Dent disease 2	Enrichment	OCRL	1.51
168	Keratosis, seborrheic	Enrichment	PIK3CA	1.51
169	Neutrophilia, hereditary	Enrichment	PIP4K2B	1.51
170	Roifman-chitayat syndrome	Enrichment	PIK3CD	1.51
171	Neurodevelopmental disorder with spasticity, hypomyelinating leukodystrophy, and brain abnormalities	Enrichment	PI4KA	1.51
172	Noonan syndrome 8	Enrichment	PIK3CA	1.51
173	Spermatogenic failure 17	Enrichment	PIK3C2G	1.51
174	Parkinson disease 20, early-onset	Enrichment	SYNJ1	1.51
175	Neutropenia, severe congenital, 7, autosomal recessive	Enrichment	PIP4K2B	1.51
176	Periventricular nodular heterotopia 8	Enrichment	ARF1	1.51
177	Interstitial nephritis, karyomegalic	Enrichment	MTMR10	1.51
178	Striatonigral degeneration, childhood-onset	Enrichment	VAC14	1.51
179	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	1.51
180	Severe congenital neutropenia 7	Enrichment	PIP4K2B	1.51
181	Respiratory system disease	Enrichment	MTM1	1.51
182	Intellectual developmental disorder, autosomal dominant 60, with seizures	Enrichment	PIP5K1A	1.51
183	Immune system disease	Enrichment	PIK3CD	1.51
184	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	PIP4K2A	1.51
185	Neurodevelopmental disorder with hyperkinetic movements, seizures, and structural brain abnormalities	Enrichment	PI4K2A	1.51
186	Combined immunodeficiency-multiple intestinal atresia	Enrichment	PI4KA	1.51
187	Short femur	Enrichment	INPP5E	1.51
188	Vacterl with hydrocephalus	Enrichment	PTEN	1.51
189	X-linked myotubular myopathy-abnormal genitalia syndrome	Enrichment	MTM1	1.51
190	Juvenile polyposis of infancy	Enrichment	PTEN	1.51
191	Dilated cardiomyopathy	Enrichment	TAFAZZIN	1.46
192	Trichohepatoenteric syndrome 1	Enrichment	AGK	1.43
193	Enophthalmos	Enrichment	CSNK2B	1.43
194	Syndactyly	Enrichment	CSNK2B	1.43
195	Endometrial cancer	Enrichment	PIK3CA, PTEN	1.38
196	Nephrotic syndrome	Enrichment	SGPL1	1.36
197	Congenital nervous system abnormality	Enrichment	PLA2G6	1.34
198	Nervous system disease	Enrichment	PLA2G6	1.34
199	Opsismodysplasia	Enrichment	INPPL1	1.34
200	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.34
201	Uvula, bifid	Enrichment	ARF3	1.34
202	Myopathy, centronuclear, x-linked	Enrichment	MTM1	1.34
203	Heparin cofactor ii deficiency	Enrichment	PI4KA	1.34
204	Charcot-marie-tooth disease, demyelinating, type 4b3	Enrichment	SBF1	1.34
205	Dent disease	Enrichment	OCRL	1.34
206	Charcot-marie-tooth disease type 4b3	Enrichment	SBF1	1.34
207	Interstitial lung disease	Enrichment	INPP5E	1.34
208	Kyphosis	Enrichment	ARF3	1.34
209	Laryngeal squamous cell carcinoma	Enrichment	PTEN	1.34
210	Atypical juvenile parkinsonism	Enrichment	SYNJ1	1.34
211	Respiratory failure	Enrichment	INPP5E	1.34
212	Keratoacanthoma	Enrichment	PIK3CA	1.34
213	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	1.21
214	Charcot-marie-tooth disease, demyelinating, type 4b2	Enrichment	SBF2	1.21
215	Charcot-marie-tooth disease type 4b2	Enrichment	SBF2	1.21
216	Cerebrovascular disease	Enrichment	PIK3CA	1.21
217	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.21
218	Glioma	Enrichment	PTEN	1.21
219	Brugada syndrome	Enrichment	GPD1L	1.14
220	Gastroesophageal reflux	Enrichment	CHAT	1.13
221	Cryptorchidism	Enrichment	MFSD2A	1.13
222	Bladder cancer	Enrichment	PIK3CA, PTEN	1.13
223	Prostate cancer	Enrichment	PIK3CA, PTEN	1.13
224	Capillary malformations, congenital	Enrichment	PIK3CA	1.12
225	Coach syndrome 1	Enrichment	INPP5E	1.12
226	Hypogonadotropic hypogonadism 1 with or without anosmia	Enrichment	PNPLA6	1.12
227	Pseudovaginal perineoscrotal hypospadias	Enrichment	FIG4	1.12
228	Macrocephaly/autism syndrome	Enrichment	PTEN	1.12
229	Hemangioma	Enrichment	PTEN	1.12
230	Acute megakaryocytic leukemia	Enrichment	PTEN	1.12
231	Joubert syndrome with ocular defect	Enrichment	INPP5E	1.12
232	Cryptorchidism, unilateral or bilateral	Enrichment	MFSD2A	1.08
233	Dyskeratosis congenita, autosomal dominant 1	Enrichment	INPP4A	1.04
234	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.04
235	Myopathy, centronuclear, 1	Enrichment	MTMR14	1.04
236	Hemihyperplasia, isolated	Enrichment	PIK3CA	1.04
237	Patent ductus arteriosus	Enrichment	INPP5E	1.04
238	Breast adenocarcinoma	Enrichment	PIK3CA	1.04
239	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.04
240	Cleft lip with or without cleft palate	Enrichment	PLEKHA5	1.04
241	Myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency	Enrichment	CHAT	1.04
242	Autism spectrum disorder	Enrichment	CSNK2A1, CSNK2B, PTEN, SBF1	1.04
243	Presynaptic congenital myasthenic syndromes	Enrichment	CHAT	1.00
244	Colorectal cancer	Enrichment	PLA2G2A	0.98
245	Nevus, epidermal	Enrichment	PIK3CA	0.98
246	Thyroid cancer, nonmedullary, 2	Enrichment	PTEN	0.98
247	Squamous cell carcinoma, head and neck	Enrichment	PTEN	0.98
248	Capillary malformation-arteriovenous malformation 1	Enrichment	PIK3CA	0.98
249	Dyskeratosis congenita, autosomal dominant 2	Enrichment	INPP4A	0.98
250	Gallbladder cancer	Enrichment	PIK3CA	0.98
251	Follicular thyroid carcinoma	Enrichment	PTEN	0.98
252	Overgrowth syndrome	Enrichment	PIK3R1	0.98
253	Lactic acidosis	Enrichment	CHAT	0.97
254	Congenital myasthenic syndrome	Enrichment	CHAT	0.90
255	Arteriovenous malformation	Enrichment	PIK3CA	0.88
256	Adult hepatocellular carcinoma	Enrichment	PIK3CA	0.88
257	Bilateral perisylvian polymicrogyria	Enrichment	PI4KA	0.88
258	Body mass index quantitative trait locus 11	Enrichment	DDHD2	0.87
259	Gastric cancer	Enrichment	PIK3CA, PTEN	0.84
260	Myopathy, x-linked, with excessive autophagy	Enrichment	PIK3CA	0.84
261	Melanoma	Enrichment	PTEN	0.84
262	Primary bone dysplasia	Enrichment	INPP5E	0.84
263	Cataract 44	Enrichment	AGK	0.82
264	Hereditary breast carcinoma	Enrichment	PIK3CA, PTEN	0.82
265	Meningioma, familial	Enrichment	PTEN	0.80
266	Osteochondrodysplasia	Enrichment	INPP5E	0.80
267	Lung non-small cell carcinoma	Enrichment	PIK3CA	0.80
268	Uterine corpus cancer	Enrichment	PTEN	0.80
269	Early-onset parkinson's disease	Enrichment	SYNJ1	0.76
270	Lip and oral cavity carcinoma	Enrichment	PIK3CA	0.76
271	Autosomal dominant non-syndromic intellectual disability	Enrichment	ARF3, CSNK2B	0.74
272	Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly	Enrichment	INPP5E	0.73
273	Clubfoot	Enrichment	INPP5E	0.73
274	Nk-cell enteropathy	Enrichment	PIK3CB	0.73
275	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	PNPLA6	0.70
276	Periventricular nodular heterotopia	Enrichment	ARF1	0.70
277	Congenital myopathy 4a, autosomal dominant	Enrichment	MTM1	0.68
278	Lynch syndrome	Enrichment	PIK3CA	0.68
279	Rhabdomyosarcoma	Enrichment	PTEN	0.65
280	Cleft palate, isolated	Enrichment	INPP5E	0.63
281	Heart, malformation of	Enrichment	ARF3	0.61
282	Diffuse large b-cell lymphoma	Enrichment	PTEN	0.59
283	Primary autosomal recessive microcephaly	Enrichment	MFSD2A	0.58
284	Centronuclear myopathy	Enrichment	MTM1	0.55
285	Hepatocellular carcinoma	Enrichment	PIK3CA	0.53
286	Kallmann syndrome	Enrichment	PNPLA6	0.52
287	Scoliosis	Enrichment	ARF3	0.50
288	Developmental and epileptic encephalopathy 1	Enrichment	SYNJ1	0.49
289	Breast cancer	Enrichment	PIK3CA, PTEN	0.48
290	Bardet-biedl syndrome	Enrichment	OSBPL8	0.48
291	Isolated joubert syndrome	Enrichment	INPP5E	0.42
292	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	SLC44A4	0.41
293	Lung cancer	Enrichment	PIK3CA	0.40
294	Dystonia	Enrichment	ARF3	0.37
295	Myopathy	Enrichment	MTM1	0.33
296	Ovarian cancer	Enrichment	PIK3CA, PTEN	0.33
297	West syndrome	Enrichment	SYNJ1	0.30
298	Joubert syndrome 1	Enrichment	INPP5E	0.26
299	Hypertelorism	Enrichment	PIK3CA	0.25
300	Mitochondrial disease	Enrichment	AGK	0.25
301	Hereditary breast ovarian cancer syndrome	Enrichment	PTEN	0.24
302	Myeloma, multiple	Enrichment	PIK3R2	0.23
303	Undetermined early-onset epileptic encephalopathy	Enrichment	SYNJ1	0.23
304	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	FIG4	0.22
305	Autism	Enrichment	ARF3	0.17
306	Complex neurodevelopmental disorder	Enrichment	CSNK2A1	0.16
307	Hereditary retinal dystrophy	Enrichment	INPP5E, OSBPL8, PNPLA6	0.08
308	Fundus dystrophy	Enrichment	INPP5E, OSBPL8, PNPLA6	0.08
309	Retinitis pigmentosa	Enrichment	INPP5E, PNPLA6	0.07
310	Inherited cancer-predisposing syndrome	Enrichment	PTEN	0.06

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Glycerophospholipid biosynthesis

Pathway Network for Glycerophospholipid biosynthesis

Pathway network for the Glycerophospholipid biosynthesis SuperPath

Member Pathways for Glycerophospholipid biosynthesis

Pathways in the Glycerophospholipid biosynthesis SuperPath

Gene overlap in member pathways for Glycerophospholipid biosynthesis SuperPath

Associated Genes for Glycerophospholipid biosynthesis

Associated Disorders for Glycerophospholipid biosynthesis

Disorders associated with Glycerophospholipid biosynthesis SuperPath

STRING Interaction Network for Glycerophospholipid biosynthesis

Sources for Glycerophospholipid biosynthesis