glycolysis (BioCyc)

Pathway network for the glycolysis (BioCyc) SuperPath

Sources:

WikiPathways
PubChem
GeneGo (Thomson Reuters)
Reactome

Pathways in the glycolysis (BioCyc) SuperPath

#	Name	Source	Genes
1	Metabolic Epileptic Disorders	WikiPathways	AADAT ACAT1 ACO1 ALDH7A1 ALDOA ALDOB ALDOC AMT BTD CBS CDO1 CTH DLAT DLD ECHS1 ENO1 ENO2 ENO3 ETHE1 FBP1 FBP2 G6PC1 GAPDH GATM GCDH GCK GLDC GOT1 GOT2 GPHN GPI GPT HADH HK1 HK2 HK3 LDHA LDHAL6B LDHB LDHC LOC102724560 MDH1 MDH2 MOCS1 MOCS2 MOCS3 MPC1 MPC2 PC PCK1 PDHA1 PFKL PFKM PFKP PGAM1 PGAM2 PGK1 PGK2 PHGDH PKLR PKM PSAT1 PSPH SFXN1 SHMT1 SHMT2 SLC25A1 SLC25A5 SLC2A1 SLC2A2 SLC2A3 SLC2A4 SLC2A5 SLC7A2 SQOR SUOX TPI1 XDH (see all 78) (see less)
2	superpathway of conversion of glucose to acetyl CoA and entry into the TCA cycle	PubChem	ACO2 ALDOA ALDOB ALDOC BPGM CS DLAT DLD DLST ENO1 ENO2 ENO3 FH GAPDH GAPDHS GCK GPI HK1 HK2 HK3 HKDC1 IDH3A IDH3B IDH3G MDH1 MDH2 OGDH PDHA1 PDHA2 PDHB PFKL PFKM PFKP PGAM1 PGAM2 PGK1 PGK2 PKLR PKM SDHA SDHB SDHC SDHD SUCLA2 SUCLG1 SUCLG2 TPI1 (see all 47) (see less)
3	Glycolysis and gluconeogenesis	WikiPathways	ALDOA ALDOB ALDOC DLAT DLD ENO1 ENO2 ENO3 FBP1 FBP2 G6PC1 GAPDH GCK GOT1 GOT2 GPI HK1 HK2 HK3 LDHA LDHAL6B LDHB LDHC MDH1 MDH2 MPC1 MPC2 PC PCK1 PDHA1 PFKL PFKM PFKP PGAM1 PGAM2 PGK1 PGK2 PKLR PKM SLC2A1 SLC2A2 SLC2A3 SLC2A4 SLC2A5 TPI1 (see all 45) (see less)
4	Glycolysis and gluconeogenesis (short map)	GeneGo (Thomson Reuters)	ALDOA ALDOB ALDOC BPGM ENO1 ENO2 ENO3 FBP1 FBP2 G6PC1 GAPDH GAPDHS GCK GPI HK1 HK2 HK3 MDH1 MDH2 PC PCK1 PCK2 PFKL PFKM PFKP PGAM1 PGAM2 PGAM4 PGK1 PGK2 PKLR PKM SLC2A4 SLC37A4 TPI1 (see all 35) (see less)
5	glycolysis	PubChem	ALDOA ALDOB ALDOC BPGM ENO1 ENO2 ENO3 GAPDH GAPDHS GCK GPI HK1 HK2 HK3 HKDC1 PFKL PFKM PFKP PGAM1 PGAM2 PGK1 PGK2 PKLR PKM TPI1 (see all 25) (see less)
6	homolactic fermentation	PubChem	ALDOA ALDOB ALDOC BPGM ENO1 ENO2 ENO3 GAPDH GAPDHS GCK GPI HK1 HK2 HK3 PFKL PFKM PFKP PGAM1 PGAM2 PGK1 PGK2 PKLR PKM TPI1 (see all 24) (see less)
7	glycolysis III (from glucose)	PubChem	ALDOA ALDOB ALDOC BPGM ENO1 ENO2 ENO3 GAPDH GAPDHS GCK GPI HK1 HK2 HK3 PFKL PFKM PFKP PGAM1 PGAM2 PGK1 PGK2 PKLR PKM TPI1 (see all 24) (see less)
8	Aerobic glycolysis	WikiPathways	ALDOA ENO1 GAPDH GPI HK1 LDHA PFKM PGAM2 PGK1 PKM SLC2A1 TPI1 (see all 12) (see less)
9	Manipulation of host energy metabolism	Reactome	ENO1 PGK1

Gene overlap in member pathways for glycolysis (BioCyc) SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PGK1	Phosphoglycerate Kinase 1	Protein Coding	9
2	ENO1	Enolase 1	Protein Coding	9
3	TPI1	Triosephosphate Isomerase 1	Protein Coding	8
4	PKM	Pyruvate Kinase M1/2	Protein Coding	8
5	PGAM2	Phosphoglycerate Mutase 2	Protein Coding	8
6	PFKM	Phosphofructokinase, Muscle	Protein Coding	8
7	HK1	Hexokinase 1	Protein Coding	8
8	GPI	Glucose-6-Phosphate Isomerase	Protein Coding	8
9	GAPDH	Glyceraldehyde-3-Phosphate Dehydrogenase	Protein Coding	8
10	ALDOA	Aldolase, Fructose-Bisphosphate A	Protein Coding	8
11	PGK2	Phosphoglycerate Kinase 2	Protein Coding	7
12	PFKL	Phosphofructokinase, Liver Type	Protein Coding	7
13	ALDOC	Aldolase, Fructose-Bisphosphate C	Protein Coding	7
14	PKLR	Pyruvate Kinase L/R	Protein Coding	7
15	PGAM1	Phosphoglycerate Mutase 1	Protein Coding	7
16	PFKP	Phosphofructokinase, Platelet	Protein Coding	7
17	HK3	Hexokinase 3	Protein Coding	7
18	HK2	Hexokinase 2	Protein Coding	7
19	GCK	Glucokinase	Protein Coding	7
20	ALDOB	Aldolase, Fructose-Bisphosphate B	Protein Coding	7
21	ENO3	Enolase 3	Protein Coding	7
22	ENO2	Enolase 2	Protein Coding	7
23	GAPDHS	Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic	Protein Coding	5
24	BPGM	Bisphosphoglycerate Mutase	Protein Coding	5
25	MDH2	Malate Dehydrogenase 2	Protein Coding	4
26	MDH1	Malate Dehydrogenase 1	Protein Coding	4
27	FBP2	Fructose-Bisphosphatase 2	Protein Coding	3
28	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	3
29	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	3
30	PDHA1	Pyruvate Dehydrogenase E1 Subunit Alpha 1	Protein Coding	3
31	PCK1	Phosphoenolpyruvate Carboxykinase 1	Protein Coding	3
32	PC	Pyruvate Carboxylase	Protein Coding	3
33	LDHA	Lactate Dehydrogenase A	Protein Coding	3
34	G6PC1	Glucose-6-Phosphatase Catalytic Subunit 1	Protein Coding	3
35	FBP1	Fructose-Bisphosphatase 1	Protein Coding	3
36	DLD	Dihydrolipoamide Dehydrogenase	Protein Coding	3
37	DLAT	Dihydrolipoamide S-Acetyltransferase	Protein Coding	3
38	LDHAL6B	Lactate Dehydrogenase A Like 6B	Protein Coding	2
39	SLC2A5	Solute Carrier Family 2 Member 5	Protein Coding	2
40	SLC2A3	Solute Carrier Family 2 Member 3	Protein Coding	2
41	SLC2A2	Solute Carrier Family 2 Member 2	Protein Coding	2
42	MPC1	Mitochondrial Pyruvate Carrier 1	Protein Coding	2
43	LDHC	Lactate Dehydrogenase C	Protein Coding	2
44	LDHB	Lactate Dehydrogenase B	Protein Coding	2
45	GOT1	Glutamic-Oxaloacetic Transaminase 1	Protein Coding	2
46	GOT2	Glutamic-Oxaloacetic Transaminase 2	Protein Coding	2
47	MPC2	Mitochondrial Pyruvate Carrier 2	Protein Coding	2
48	HKDC1	Hexokinase Domain Containing 1	Protein Coding	2
49	SLC25A1	Solute Carrier Family 25 Member 1	Protein Coding	1
50	SLC7A2	Solute Carrier Family 7 Member 2	Protein Coding	1
51	CDO1	Cysteine Dioxygenase Type 1	Protein Coding	1
52	SUOX	Sulfite Oxidase	Protein Coding	1
53	ETHE1	ETHE1 Persulfide Dioxygenase	Protein Coding	1
54	SQOR	Sulfide Quinone Oxidoreductase	Protein Coding	1
55	GATM	Glycine Amidinotransferase	Protein Coding	1
56	GCDH	Glutaryl-CoA Dehydrogenase	Protein Coding	1
57	AADAT	Aminoadipate Aminotransferase	Protein Coding	1
58	PSAT1	Phosphoserine Aminotransferase 1	Protein Coding	1
59	PSPH	Phosphoserine Phosphatase	Protein Coding	1
60	PHGDH	Phosphoglycerate Dehydrogenase	Protein Coding	1
61	BTD	Biotinidase	Protein Coding	1
62	GPT	Glutamic--Pyruvic Transaminase	Protein Coding	1
63	ACAT1	Acetyl-CoA Acetyltransferase 1	Protein Coding	1
64	HADH	Hydroxyacyl-CoA Dehydrogenase	Protein Coding	1
65	ECHS1	Enoyl-CoA Hydratase, Short Chain 1	Protein Coding	1
66	SLC25A5	Solute Carrier Family 25 Member 5	Protein Coding	1
67	ACO1	Aconitase 1	Protein Coding	1
68	XDH	Xanthine Dehydrogenase	Protein Coding	1
69	CTH	Cystathionine Gamma-Lyase	Protein Coding	1
70	CBS	Cystathionine Beta-Synthase	Protein Coding	1
71	LOC102724560	Cystathionine Beta-Synthase Like	Protein Coding	1
72	SFXN1	Sideroflexin 1	Protein Coding	1
73	SHMT2	Serine Hydroxymethyltransferase 2	Protein Coding	1
74	SHMT1	Serine Hydroxymethyltransferase 1	Protein Coding	1
75	ALDH7A1	Aldehyde Dehydrogenase 7 Family Member A1	Protein Coding	1
76	MOCS2	Molybdenum Cofactor Synthesis 2	Protein Coding	1
77	MOCS1	Molybdenum Cofactor Synthesis 1	Protein Coding	1
78	AMT	Aminomethyltransferase	Protein Coding	1
79	GLDC	Glycine Decarboxylase	Protein Coding	1
80	GPHN	Gephyrin	Protein Coding	1
81	MOCS3	Molybdenum Cofactor Synthesis 3	Protein Coding	1
82	PDHA2	Pyruvate Dehydrogenase E1 Subunit Alpha 2	Protein Coding	1
83	OGDH	Oxoglutarate Dehydrogenase	Protein Coding	1
84	SUCLA2	Succinate-CoA Ligase ADP-Forming Subunit Beta	Protein Coding	1
85	SDHD	Succinate Dehydrogenase Complex Subunit D	Protein Coding	1
86	IDH3G	Isocitrate Dehydrogenase (NAD(+)) 3 Non-Catalytic Subunit Gamma	Protein Coding	1
87	SDHC	Succinate Dehydrogenase Complex Subunit C	Protein Coding	1
88	FH	Fumarate Hydratase	Protein Coding	1
89	ACO2	Aconitase 2	Protein Coding	1
90	SUCLG2	Succinate-CoA Ligase GDP-Forming Subunit Beta	Protein Coding	1
91	IDH3B	Isocitrate Dehydrogenase (NAD(+)) 3 Non-Catalytic Subunit Beta	Protein Coding	1
92	SUCLG1	Succinate-CoA Ligase GDP/ADP-Forming Subunit Alpha	Protein Coding	1
93	DLST	Dihydrolipoamide S-Succinyltransferase	Protein Coding	1
94	SDHA	Succinate Dehydrogenase Complex Flavoprotein Subunit A	Protein Coding	1
95	SDHB	Succinate Dehydrogenase Complex Iron Sulfur Subunit B	Protein Coding	1
96	PDHB	Pyruvate Dehydrogenase E1 Subunit Beta	Protein Coding	1
97	CS	Citrate Synthase	Protein Coding	1
98	IDH3A	Isocitrate Dehydrogenase (NAD(+)) 3 Catalytic Subunit Alpha	Protein Coding	1
99	SLC37A4	Solute Carrier Family 37 Member 4	Protein Coding	1
100	PCK2	Phosphoenolpyruvate Carboxykinase 2, Mitochondrial	Protein Coding	1
101	PGAM4	Phosphoglycerate Mutase Family Member 4	Protein Coding	1

Disorders associated with glycolysis (BioCyc) SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Tuberculosis	Direct
2	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	DLST, FH, MDH2, SDHA, SDHB, SDHC, SDHD	11.25
3	Carney triad	Enrichment	SDHA, SDHB, SDHC	7.41
4	Paraganglioma	Enrichment	SDHA, SDHB, SDHD	7.41
5	Pheochromocytoma/paraganglioma syndrome 1	Enrichment	SDHA, SDHB, SDHD	6.81
6	Mitochondrial complex ii deficiency	Enrichment	SDHA, SDHB, SDHD	6.81
7	Paraganglioma and gastric stromal sarcoma	Enrichment	SDHB, SDHC, SDHD	6.41
8	Gastrointestinal stromal tumor	Enrichment	SDHA, SDHB, SDHC	5.87
9	Glycogen storage disease	Enrichment	G6PC1, PFKM, SLC37A4	5.59
10	Cowden syndrome	Enrichment	SDHB, SDHC, SDHD	5.49
11	Fanconi-bickel syndrome	Enrichment	LDHA, SLC2A2	4.97
12	Pheochromocytoma	Enrichment	SDHA, SDHB, SDHD	4.86
13	Phosphoenolpyruvate carboxykinase deficiency	Enrichment	PCK1, PCK2	4.71
14	Molybdenum cofactor deficiency	Enrichment	MOCS1, MOCS2	4.49
15	Pheochromocytoma/paraganglioma syndrome 4	Enrichment	SDHB, SDHD	4.45
16	Glycogen storage disease ia	Enrichment	G6PC1, SLC37A4	4.41
17	Hemolytic anemia	Enrichment	GPI, PKLR	4.20
18	Mitochondrial complex ii deficiency, nuclear type 1	Enrichment	SDHA, SDHD	4.15
19	Inherited cancer-predisposing syndrome	Enrichment	FH, SDHA, SDHB, SDHC, SDHD	4.05
20	Molybdenum cofactor deficiency, type a	Enrichment	MOCS1, MOCS2	4.01
21	Sporadic pheochromocytoma/secreting paraganglioma	Enrichment	SDHB, SDHD	3.76
22	Atypical glycine encephalopathy	Enrichment	AMT, GLDC	3.71
23	Type 2 diabetes mellitus	Enrichment	GCK, SLC2A2, SLC2A4	3.45
24	Hyperinsulinemic hypoglycemia, familial, 1	Enrichment	GCK, HADH	3.32
25	Glycine encephalopathy	Enrichment	AMT, GLDC	3.32
26	Nonsyndromic genetic hyperinsulinism	Enrichment	GCK, HADH	3.32
27	Anemia, congenital, nonspherocytic hemolytic, 5	Enrichment	HK1	3.05
28	Phosphoglycerate kinase 1 deficiency	Enrichment	PGK1	3.05
29	Stomatin-deficient cryohydrocytosis with neurologic defects	Enrichment	SLC2A1	3.05
30	Triosephosphate isomerase deficiency	Enrichment	TPI1	3.05
31	Retinitis pigmentosa 79	Enrichment	HK1	3.05
32	Neuropathy, hereditary motor and sensory, russe type	Enrichment	HK1	3.05
33	Neurodevelopmental disorder with visual defects and brain anomalies	Enrichment	HK1	3.05
34	Epilepsy, idiopathic generalized 12	Enrichment	SLC2A1	3.05
35	Anemia, congenital, nonspherocytic hemolytic, 4	Enrichment	GPI	3.05
36	Epilepsy with myoclonic absences	Enrichment	SLC2A1	3.05
37	Male infertility due to obstructive azoospermia	Enrichment	PGK1	3.05
38	Hereditary cryohydrocytosis with reduced stomatin	Enrichment	SLC2A1	3.05
39	Glycine encephalopathy 1	Enrichment	AMT, GLDC	3.05
40	Rhabdomyosarcoma	Enrichment	SDHA, SDHC	2.86
41	Glycogen storage disease vii	Enrichment	PFKM	2.75
42	Dystonia 9	Enrichment	SLC2A1	2.75
43	Glut1 deficiency syndrome 1	Enrichment	SLC2A1	2.75
44	Microcephaly 21, primary, autosomal recessive	Enrichment	GAPDH	2.75
45	Glucose transporter type 1 deficiency syndrome	Enrichment	SLC2A1	2.75
46	Glycogen storage disease xii	Enrichment	ALDOA	2.75
47	Adenosine triphosphate, elevated, of erythrocytes	Enrichment	PKLR	2.75
48	Erythrocytosis, familial, 8	Enrichment	BPGM	2.75
49	Anemia, congenital, nonspherocytic hemolytic, 2	Enrichment	PKLR	2.75
50	Glycogen storage disease xiii	Enrichment	ENO3	2.75
51	Maturity-onset diabetes of the young, type 2	Enrichment	GCK	2.75
52	Hyperinsulinemic hypoglycemia, familial, 3	Enrichment	GCK	2.75
53	Gestational diabetes	Enrichment	GCK	2.75
54	Autosomal recessive secondary polycythemia not associated with vhl gene	Enrichment	BPGM	2.75
55	Phosphoenolpyruvate carboxykinase deficiency, cytosolic	Enrichment	PCK1	2.59
56	Fructose-1,6-bisphosphatase deficiency	Enrichment	FBP1	2.59
57	Glycogen storage disease ic	Enrichment	SLC37A4	2.59
58	Glycogen storage disease ib	Enrichment	SLC37A4	2.59
59	Congenital disorder of glycosylation, type iiw	Enrichment	SLC37A4	2.59
60	Leukodystrophy, childhood-onset, remitting	Enrichment	FBP2	2.59
61	Developmental and epileptic encephalopathy 51	Enrichment	MDH2	2.59
62	Glycogen storage disease due to glucose-6-phosphatase deficiency type ib	Enrichment	SLC37A4	2.59
63	Glycogen storage disease type 1 due to slc37a4 mutation	Enrichment	SLC37A4	2.59
64	Glut1 deficiency syndrome 2	Enrichment	SLC2A1	2.58
65	Chromosome 17q23.1-q23.2 deletion syndrome	Enrichment	SLC2A1	2.58
66	Developmental and epileptic encephalopathy 1	Enrichment	MDH2, SLC2A1	2.51
67	Aspartate aminotransferase, serum level of, quantitative trait locus 1	Enrichment	GOT1	2.48
68	Lactate dehydrogenase b deficiency	Enrichment	LDHB	2.48
69	Mitochondrial pyruvate carrier deficiency	Enrichment	MPC1	2.48
70	Hereditary leiomyomatosis and renal cell cancer	Enrichment	FH	2.46
71	Mitochondrial dna depletion syndrome 9	Enrichment	SUCLG1	2.46
72	Oxoglutarate dehydrogenase deficiency	Enrichment	OGDH	2.46
73	Retinitis pigmentosa 99	Enrichment	IDH3G	2.46
74	Fumarase deficiency	Enrichment	FH	2.46
75	Pheochromocytoma/paraganglioma syndrome 3	Enrichment	SDHC	2.46
76	Pheochromocytoma/paraganglioma syndrome 5	Enrichment	SDHA	2.46
77	Retinitis pigmentosa 90	Enrichment	IDH3A	2.46
78	Pheochromocytoma/paraganglioma syndrome 7	Enrichment	DLST	2.46
79	Mitochondrial dna depletion syndrome 5	Enrichment	SUCLA2	2.46
80	Retinitis pigmentosa 46	Enrichment	IDH3B	2.46
81	Leiomyoma cutis	Enrichment	FH	2.46
82	Cardiomyopathy, dilated, 1gg	Enrichment	SDHA	2.46
83	Spermatogenic failure 70	Enrichment	PDHA2	2.46
84	Fumarate hydratase deficiency	Enrichment	FH	2.46
85	Neurodegeneration with ataxia and late-onset optic atrophy	Enrichment	SDHA	2.46
86	Carcinoid syndrome	Enrichment	SDHD	2.46
87	Suclg1-related mitochondrial dna depletion syndrome, encephalomyopathic form with methylmalonic aciduria	Enrichment	SUCLG1	2.46
88	Glycogen storage disease x	Enrichment	PGAM2	2.45
89	Maturity-onset diabetes of the young, type 1	Enrichment	GCK	2.45
90	Fructose intolerance, hereditary	Enrichment	ALDOB	2.45
91	Diabetes mellitus, permanent neonatal, 1	Enrichment	GCK	2.45
92	Bone marrow failure syndrome 2	Enrichment	GCK	2.45
93	Phosphoenolpyruvate carboxykinase deficiency, mitochondrial	Enrichment	PCK2	2.29
94	Developmental and epileptic encephalopathy 88	Enrichment	MDH1	2.29
95	Hereditary spherocytosis	Enrichment	GPI	2.28
96	Nijmegen breakage syndrome	Enrichment	GCK	2.28
97	Retinitis pigmentosa 92	Enrichment	HKDC1	2.26
98	Cystathioninuria	Enrichment	CTH	2.24
99	Neu-laxova syndrome 1	Enrichment	PHGDH	2.24
100	3-hydroxyacyl-coa dehydrogenase deficiency	Enrichment	HADH	2.24
101	Epilepsy, early-onset, 4, vitamin b6-dependent	Enrichment	ALDH7A1	2.24
102	Phosphoglycerate dehydrogenase deficiency	Enrichment	PHGDH	2.24
103	Biotinidase deficiency	Enrichment	BTD	2.24
104	Combined d-2- and l-2-hydroxyglutaric aciduria	Enrichment	SLC25A1	2.24
105	Sulfite oxidase deficiency, isolated	Enrichment	SUOX	2.24
106	Myasthenic syndrome, congenital, 23, presynaptic	Enrichment	SLC25A1	2.24
107	Hyperhomocysteinemia	Enrichment	CBS	2.24
108	Phosphoserine aminotransferase deficiency	Enrichment	PSAT1	2.24
109	Biotin deficiency	Enrichment	BTD	2.24
110	Sulfide:quinone oxidoreductase deficiency	Enrichment	SQOR	2.24
111	Phosphoserine phosphatase deficiency	Enrichment	PSPH	2.24
112	2-hydroxyglutaric aciduria	Enrichment	SLC25A1	2.24
113	Neurodevelopmental disorder with cardiomyopathy, spasticity, and brain abnormalities	Enrichment	SHMT2	2.24
114	Molybdenum cofactor deficiency, type b2	Enrichment	MOCS3	2.24
115	Neu-laxova syndrome 2	Enrichment	PSAT1	2.24
116	Neurometabolic disorder due to serine deficiency	Enrichment	PSAT1	2.24
117	Neu-laxova syndrome due to 3-phosphoserine phosphatase deficiency	Enrichment	PSPH	2.24
118	Paroxysmal dystonia	Enrichment	SLC2A1	2.21
119	Dihydrolipoamide dehydrogenase deficiency	Enrichment	DLD	2.18
120	Methemoglobinemia due to deficiency of methemoglobin reductase	Enrichment	DLD	2.18
121	Pyruvate dehydrogenase e2 deficiency	Enrichment	DLAT	2.18
122	Developmental and epileptic encephalopathy 82	Enrichment	GOT2	2.18
123	Leiomyoma, uterine	Enrichment	FH	2.16
124	Polymyoclonus, infantile	Enrichment	SDHA	2.16
125	Porphyria, acute intermittent	Enrichment	ACO2	2.16
126	Pyruvate dehydrogenase e1-beta deficiency	Enrichment	PDHB	2.16
127	Acute porphyria	Enrichment	ACO2	2.16
128	Spinocerebellar ataxia 45	Enrichment	FH	2.16
129	Alternating hemiplegia of childhood	Enrichment	SLC2A1	2.15
130	Maturity-onset diabetes of the young, type 3	Enrichment	GCK	2.15
131	Pyruvate carboxylase deficiency	Enrichment	PC	2.11
132	Myoclonic-atonic epilepsy	Enrichment	SLC2A1	2.10
133	West syndrome	Enrichment	MDH2, SLC2A1	2.03
134	Mitochondrial complex iv deficiency, nuclear type 2	Enrichment	SDHB	1.98
135	Mitochondrial complex iii deficiency, nuclear type 2	Enrichment	SDHD	1.98
136	Infantile cerebellar-retinal degeneration	Enrichment	ACO2	1.98
137	Optic atrophy 9	Enrichment	ACO2	1.98
138	Brain cancer	Enrichment	SDHA	1.98
139	Renal cell carcinoma	Enrichment	SDHB	1.98
140	Fanconi renotubular syndrome 1	Enrichment	GATM	1.94
141	Hyperekplexia 1	Enrichment	GPHN	1.94
142	Alpha-methylacetoacetic aciduria	Enrichment	ACAT1	1.94
143	Molybdenum cofactor deficiency, type b1	Enrichment	MOCS2	1.94
144	Encephalopathy, ethylmalonic	Enrichment	ETHE1	1.94
145	Xanthinuria, type i	Enrichment	XDH	1.94
146	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	HADH	1.94
147	Retinal dystrophy, juvenile cataracts, and short stature syndrome	Enrichment	GPHN	1.94
148	Mitochondrial short-chain enoyl-coa hydratase 1 deficiency	Enrichment	ECHS1	1.94
149	Glycine encephalopathy 2	Enrichment	AMT	1.94
150	Molybdenum cofactor deficiency, type c	Enrichment	GPHN	1.94
151	Cerebral creatine deficiency syndrome 3	Enrichment	GATM	1.94
152	Pyridoxine-dependent-developmental and epileptic encephalopathy	Enrichment	ALDH7A1	1.94
153	Hypoglycemia	Enrichment	G6PC1	1.89
154	Huntington disease	Enrichment	SLC2A3	1.88
155	Pyruvate dehydrogenase e1-alpha deficiency	Enrichment	PDHA1	1.88
156	Spermatogenic failure 1	Enrichment	PDHA2	1.86
157	Pilocytic astrocytoma	Enrichment	SDHA	1.86
158	Autosomal recessive isolated optic atrophy	Enrichment	ACO2	1.86
159	Permanent neonatal diabetes mellitus	Enrichment	GCK	1.85
160	Orofacial cleft 1	Enrichment	HKDC1	1.78
161	Homocystinuria due to cystathionine beta-synthase deficiency	Enrichment	CBS	1.77
162	Leber congenital amaurosis 13	Enrichment	GPHN	1.77
163	Leukodystrophy, hypomyelinating, 2	Enrichment	GCDH	1.77
164	Developmental and epileptic encephalopathy 13	Enrichment	ALDH7A1	1.77
165	Glycosylphosphatidylinositol biosynthesis defect 17	Enrichment	GPHN	1.77
166	Fanconi syndrome	Enrichment	GATM	1.77
167	Hyperinsulinemic hypoglycemia	Enrichment	HADH	1.77
168	Xanthinuria, type ii	Enrichment	XDH	1.77
169	Arachnoid cyst	Enrichment	GPHN	1.77
170	Homocystinuria	Enrichment	CBS	1.77
171	Von hippel-lindau syndrome	Enrichment	SDHB	1.76
172	Neutropenia	Enrichment	SLC37A4	1.75
173	Diabetes mellitus	Enrichment	GCK	1.71
174	Epilepsy	Enrichment	ALDH7A1, SLC2A1	1.66
175	Anemia, congenital dyserythropoietic, type iva	Enrichment	GCDH	1.64
176	Fetal hemoglobin quantitative trait locus 6	Enrichment	GCDH	1.64
177	Ciliary dyskinesia, primary, 29	Enrichment	GCDH	1.64
178	Macular dystrophy with or without cone dysfunction	Enrichment	GPHN	1.64
179	Generalized epilepsy	Enrichment	GLDC	1.64
180	Primary fanconi renotubular syndrome	Enrichment	GATM	1.64
181	Strabismus	Enrichment	SLC2A1	1.63
182	Immune deficiency disease	Enrichment	SLC37A4	1.55
183	Glutaric acidemia i	Enrichment	GCDH	1.55
184	Hyperekplexia	Enrichment	GPHN	1.55
185	Anxiety	Enrichment	GPHN	1.47
186	Maturity-onset diabetes of the young	Enrichment	GCK	1.46
187	Benign epilepsy with centrotemporal spikes	Enrichment	SLC2A1	1.45
188	Retinitis pigmentosa	Enrichment	HK1, IDH3A, IDH3B	1.43
189	Centralopathic epilepsy	Enrichment	SLC2A1	1.43
190	Lactic acidosis	Enrichment	DLD	1.41
191	Congenital long qt syndrome	Enrichment	SLC2A2	1.41
192	Congenital disorder of glycosylation, type in	Enrichment	SLC37A4	1.37
193	Isolated macular dystrophy	Enrichment	ACO2	1.32
194	Sudden infant death syndrome	Enrichment	PDHA1	1.26
195	Presynaptic congenital myasthenic syndromes	Enrichment	SLC25A1	1.21
196	Azoospermia	Enrichment	PDHA2	1.17
197	Hepatocellular carcinoma	Enrichment	FH	1.13
198	Hereditary retinal dystrophy	Enrichment	ACO2, HK1, IDH3A	1.10
199	Fundus dystrophy	Enrichment	ACO2, HK1, IDH3A	1.10
200	Hydrocephalus, congenital, 1	Enrichment	ALDH7A1	1.05
201	Autism spectrum disorder	Enrichment	HK1	1.03
202	Long qt syndrome 1	Enrichment	SLC2A2	1.02
203	Microcephaly	Enrichment	SLC2A1	0.98
204	Developmental and epileptic encephalopathy	Enrichment	GOT2	0.95
205	Congenital nervous system abnormality	Enrichment	ALDH7A1, ETHE1	0.91
206	Nervous system disease	Enrichment	ALDH7A1, ETHE1	0.91
207	Optic atrophy plus syndrome	Enrichment	ACO2	0.85
208	Hereditary breast carcinoma	Enrichment	SDHA	0.85
209	Stargardt disease 1	Enrichment	GPHN	0.80
210	Familial isolated dilated cardiomyopathy	Enrichment	SDHA	0.77
211	Connective tissue disease	Enrichment	CBS	0.77
212	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	PDHA2	0.75
213	Eye disease	Enrichment	GPHN	0.74
214	Cerebral palsy	Enrichment	GPHN	0.70
215	Leigh syndrome, nuclear	Enrichment	SDHA	0.67
216	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	CBS	0.65
217	Breast cancer	Enrichment	SDHA	0.64
218	Leigh disease	Enrichment	SDHA	0.63
219	Body mass index quantitative trait locus 11	Enrichment	GLDC	0.60
220	Ovarian cancer	Enrichment	FH	0.53
221	Cone-rod dystrophy 2	Enrichment	GPHN	0.49
222	Leber plus disease	Enrichment	GPHN	0.37

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

glycolysis (BioCyc)

Pathway Network for glycolysis (BioCyc)

Pathway network for the glycolysis (BioCyc) SuperPath

Member Pathways for glycolysis (BioCyc)

Pathways in the glycolysis (BioCyc) SuperPath

Gene overlap in member pathways for glycolysis (BioCyc) SuperPath

Associated Genes for glycolysis (BioCyc)

Associated Disorders for glycolysis (BioCyc)

Disorders associated with glycolysis (BioCyc) SuperPath

STRING Interaction Network for glycolysis (BioCyc)

Sources for glycolysis (BioCyc)