Glycosaminoglycan synthesis in fibroblasts

No Pathway Network information available for Glycosaminoglycan synthesis in fibroblasts

Pathways in the Glycosaminoglycan synthesis in fibroblasts SuperPath

#	Name	Source	Genes
1	Glycosaminoglycan synthesis in fibroblasts	WikiPathways	B3GALT6 B3GAT1 B3GAT2 B3GAT3 B4GALT7 CHPF CHPF2 CHST1 CHST11 CHST12 CHST13 CHST14 CHST15 CHST3 CHST7 CHSY1 CHSY3 CSGALNACT1 CSGALNACT2 DSE EXT1 EXT2 EXTL1 EXTL2 EXTL3 GLCE HS2ST1 HS3ST1 HS3ST2 HS3ST3A1 HS3ST3B1 HS6ST1 HS6ST2 HS6ST3 NDST1 NDST2 NDST3 NDST4 UST XYLT1 XYLT2 (see all 41) (see less)
2	chondroitin sulfate biosynthesis (late stages)	PubChem	CHST1 CHST11 CHST12 CHST13 CHST15 CHST3 CHST7 UST (see all 8) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CHST1	Carbohydrate Sulfotransferase 1	Protein Coding	2
2	CHST7	Carbohydrate Sulfotransferase 7	Protein Coding	2
3	CHST3	Carbohydrate Sulfotransferase 3	Protein Coding	2
4	CHST12	Carbohydrate Sulfotransferase 12	Protein Coding	2
5	CHST15	Carbohydrate Sulfotransferase 15	Protein Coding	2
6	CHST11	Carbohydrate Sulfotransferase 11	Protein Coding	2
7	CHST13	Carbohydrate Sulfotransferase 13	Protein Coding	2
8	UST	Uronyl 2-Sulfotransferase	Protein Coding	2
9	HS3ST1	Heparan Sulfate-Glucosamine 3-Sulfotransferase 1	Protein Coding	1
10	HS3ST2	Heparan Sulfate-Glucosamine 3-Sulfotransferase 2	Protein Coding	1
11	HS3ST3A1	Heparan Sulfate-Glucosamine 3-Sulfotransferase 3A1	Protein Coding	1
12	HS2ST1	Heparan Sulfate 2-O-Sulfotransferase 1	Protein Coding	1
13	NDST3	N-Deacetylase And N-Sulfotransferase 3	Protein Coding	1
14	HS6ST2	Heparan Sulfate 6-O-Sulfotransferase 2	Protein Coding	1
15	CHPF	Chondroitin Polymerizing Factor	Protein Coding	1
16	CSGALNACT2	Chondroitin Sulfate N-Acetylgalactosaminyltransferase 2	Protein Coding	1
17	CHPF2	Chondroitin Polymerizing Factor 2	Protein Coding	1
18	CHSY3	Chondroitin Sulfate Synthase 3	Protein Coding	1
19	HS6ST3	Heparan Sulfate 6-O-Sulfotransferase 3	Protein Coding	1
20	GLCE	Glucuronic Acid Epimerase	Protein Coding	1
21	EXTL2	Exostosin Like Glycosyltransferase 2	Protein Coding	1
22	HS3ST3B1	Heparan Sulfate-Glucosamine 3-Sulfotransferase 3B1	Protein Coding	1
23	HS6ST1	Heparan Sulfate 6-O-Sulfotransferase 1	Protein Coding	1
24	NDST2	N-Deacetylase And N-Sulfotransferase 2	Protein Coding	1
25	NDST4	N-Deacetylase And N-Sulfotransferase 4	Protein Coding	1
26	XYLT2	Xylosyltransferase 2	Protein Coding	1
27	XYLT1	Xylosyltransferase 1	Protein Coding	1
28	CSGALNACT1	Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1	Protein Coding	1
29	NDST1	N-Deacetylase And N-Sulfotransferase 1	Protein Coding	1
30	DSE	Dermatan Sulfate Epimerase	Protein Coding	1
31	B3GAT1	Beta-1,3-Glucuronyltransferase 1	Protein Coding	1
32	B3GAT3	Beta-1,3-Glucuronyltransferase 3	Protein Coding	1
33	CHSY1	Chondroitin Sulfate Synthase 1	Protein Coding	1
34	EXTL3	Exostosin Like Glycosyltransferase 3	Protein Coding	1
35	EXTL1	Exostosin Like Glycosyltransferase 1	Protein Coding	1
36	EXT2	Exostosin Glycosyltransferase 2	Protein Coding	1
37	EXT1	Exostosin Glycosyltransferase 1	Protein Coding	1
38	B3GAT2	Beta-1,3-Glucuronyltransferase 2	Protein Coding	1
39	B3GALT6	Beta-1,3-Galactosyltransferase 6	Protein Coding	1
40	CHST14	Carbohydrate Sulfotransferase 14	Protein Coding	1
41	B4GALT7	Beta-1,4-Galactosyltransferase 7	Protein Coding	1

Disorders associated with Glycosaminoglycan synthesis in fibroblasts SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Spondyloepiphyseal dysplasia with congenital joint dislocations	Enrichment	B3GALT6, B3GAT3, B4GALT7, CHST3	8.96
2	Multiple joint dislocations, short stature, and craniofacial dysmorphism with or without congenital heart defects	Enrichment	B3GAT3, B4GALT7, CHST3	7.59
3	Larsen-like syndrome b3gat3 type	Enrichment	B3GAT3, B4GALT7, CHST3	7.59
4	Exostoses, multiple, type i	Enrichment	EXT1, EXT2	5.05
5	Ehlers-danlos syndrome, spondylodysplastic type, 2	Enrichment	B3GALT6, B4GALT7	5.05
6	Musculocontractural ehlers-danlos syndrome	Enrichment	CHST14, DSE	4.57
7	Desbuquois dysplasia 1	Enrichment	CSGALNACT1, XYLT1	3.88
8	Pseudoxanthoma elasticum	Enrichment	XYLT1, XYLT2	3.88
9	Osteochondrodysplasia, brachydactyly, and overlapping malformed digits	Enrichment	CHST11	3.23
10	Larsen syndrome	Enrichment	CHST3	2.75
11	Chondrosarcoma	Enrichment	EXT1	2.52
12	Al-gazali syndrome	Enrichment	B3GALT6	2.52
13	Ehlers-danlos syndrome, musculocontractural type, 2	Enrichment	DSE	2.52
14	Ehlers-danlos syndrome, spondylodysplastic type, 1	Enrichment	B4GALT7	2.52
15	Neurofacioskeletal syndrome with or without renal agenesis	Enrichment	HS2ST1	2.52
16	Spondyloepimetaphyseal dysplasia with joint laxity, type 1, with or without fractures	Enrichment	B3GALT6	2.52
17	Intellectual developmental disorder, autosomal recessive 46	Enrichment	NDST1	2.52
18	Immunoskeletal dysplasia with neurodevelopmental abnormalities	Enrichment	EXTL3	2.52
19	Paganini-miozzo syndrome	Enrichment	HS6ST2	2.52
20	Spondyloocular syndrome	Enrichment	XYLT2	2.52
21	Hypogonadotropic hypogonadism 15 with or without anosmia	Enrichment	HS6ST1	2.52
22	Hereditary multiple osteochondromas	Enrichment	EXT1	2.52
23	Skeletal dysplasia, mild, with joint laxity and advanced bone age	Enrichment	CSGALNACT1	2.52
24	Exostosis	Enrichment	EXT1	2.52
25	Arteriosclerosis	Enrichment	HS3ST1	2.52
26	Spondylodysplastic ehlers-danlos syndrome	Enrichment	B4GALT7	2.52
27	Spondyloepimetaphyseal dysplasia with joint laxity	Enrichment	B3GALT6	2.52
28	Hereditary multiple exostoses	Enrichment	EXT1	2.52
29	Xylt1-congenital disorder of glycosylation	Enrichment	XYLT1	2.52
30	Skeletal dysplasia-t-cell immunodeficiency-developmental delay syndrome	Enrichment	EXTL3	2.52
31	Exostoses, multiple, type ii	Enrichment	EXT2	2.22
32	Ehlers-danlos syndrome, musculocontractural type, 1	Enrichment	CHST14	2.22
33	Seizures, scoliosis, and macrocephaly/microcephaly syndrome	Enrichment	EXT2	2.22
34	Temtamy preaxial brachydactyly syndrome	Enrichment	CHSY1	2.22
35	Sudden infant death with dysgenesis of the testes syndrome	Enrichment	DSE	2.04
36	Desbuquois dysplasia 2	Enrichment	XYLT1	2.04
37	Trichorhinophalangeal syndrome, type ii	Enrichment	EXT1	1.92
38	Potocki-shaffer syndrome	Enrichment	EXT2	1.92
39	Coronary artery anomaly	Enrichment	HS3ST1	1.92
40	Ovarian cancer	Enrichment	EXT1, EXT2	1.43
41	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	HS6ST1	1.28
42	Hepatoblastoma	Enrichment	EXT2	1.21
43	Kallmann syndrome	Enrichment	HS6ST1	1.17
44	Autosomal recessive non-syndromic intellectual disability	Enrichment	NDST1	0.79
45	Complex neurodevelopmental disorder	Enrichment	HS2ST1	0.50
46	Inherited cancer-predisposing syndrome	Enrichment	EXT2	0.48

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Glycosaminoglycan synthesis in fibroblasts

Pathway Network for Glycosaminoglycan synthesis in fibroblasts

Member Pathways for Glycosaminoglycan synthesis in fibroblasts

Pathways in the Glycosaminoglycan synthesis in fibroblasts SuperPath

Associated Genes for Glycosaminoglycan synthesis in fibroblasts

Associated Disorders for Glycosaminoglycan synthesis in fibroblasts

Disorders associated with Glycosaminoglycan synthesis in fibroblasts SuperPath

STRING Interaction Network for Glycosaminoglycan synthesis in fibroblasts

Sources for Glycosaminoglycan synthesis in fibroblasts