Glycosphingolipid transport
Pathways in the Glycosphingolipid transport SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Glycosphingolipid transport | Reactome |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | CLN3 | CLN3 Lysosomal/Endosomal Transmembrane Protein, Battenin | Protein Coding | 1 |
| 2 | ESYT1 | Extended Synaptotagmin 1 | Protein Coding | 1 |
| 3 | ARF1 | ARF GTPase 1 | Protein Coding | 1 |
| 4 | GLTP | Glycolipid Transfer Protein | Protein Coding | 1 |
| 5 | ESYT2 | Extended Synaptotagmin 2 | Protein Coding | 1 |
| 6 | CPTP | Ceramide-1-Phosphate Transfer Protein | Protein Coding | 1 |
| 7 | ESYT3 | Extended Synaptotagmin 3 | Protein Coding | 1 |
| 8 | PLEKHA8 | Pleckstrin Homology Domain Containing A8 | Protein Coding | 1 |
Disorders associated with Glycosphingolipid transport SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Ceroid lipofuscinosis, neuronal, 3 | Enrichment | CLN3 | 2.93 |
| 2 | Periventricular nodular heterotopia 8 | Enrichment | ARF1 | 2.93 |
| 3 | Periventricular nodular heterotopia | Enrichment | ARF1 | 2.08 |
| 4 | Neuronal ceroid lipofuscinosis | Enrichment | CLN3 | 2.05 |
| 5 | Stargardt disease 1 | Enrichment | CLN3 | 1.76 |
| 6 | Cone-rod dystrophy 2 | Enrichment | CLN3 | 1.40 |
| 7 | Retinitis pigmentosa | Enrichment | CLN3 | 0.93 |
| 8 | Hereditary retinal dystrophy | Enrichment | CLN3 | 0.80 |
| 9 | Fundus dystrophy | Enrichment | CLN3 | 0.80 |
