Glypican 1 network

No Pathway Network information available for Glypican 1 network

Pathways in the Glypican 1 network SuperPath

#	Name	Source	Genes
1	Glypican 1 network	PubChem	APP CRIPTO FGF2 FGFR1 FLT1 GPC1 LAMA1 LCK NRG1 PLA2G2A PRNP SERPINC1 SLIT2 SMAD2 TGFB1 TGFB3 TGFBR1 TGFBR2 VEGFA (see all 19) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	NRG1	Neuregulin 1	Protein Coding	1
2	LCK	LCK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
3	TGFBR2	Transforming Growth Factor Beta Receptor 2	Protein Coding	1
4	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	1
5	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	1
6	SERPINC1	Serpin Family C Member 1	Protein Coding	1
7	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	1
8	CRIPTO	Cripto, EGF-CFC Family Member	Protein Coding	1
9	SMAD2	SMAD Family Member 2	Protein Coding	1
10	LAMA1	Laminin Subunit Alpha 1	Protein Coding	1
11	SLIT2	Slit Guidance Ligand 2	Protein Coding	1
12	GPC1	Glypican 1	Protein Coding	1
13	PRNP	Prion Protein (Kanno Blood Group)	Protein Coding	1
14	APP	Amyloid Beta Precursor Protein	Protein Coding	1
15	FGF2	Fibroblast Growth Factor 2	Protein Coding	1
16	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	1
17	PLA2G2A	Phospholipase A2 Group IIA	Protein Coding	1
18	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1
19	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1

Disorders associated with Glypican 1 network SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Loeys-dietz syndrome	Enrichment	SMAD2, TGFB3, TGFBR1, TGFBR2	9.43
2	Loeys-dietz syndrome 1	Enrichment	SMAD2, TGFBR1, TGFBR2	8.63
3	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SMAD2, TGFB3, TGFBR1, TGFBR2	6.44
4	Loeys-dietz syndrome 2	Enrichment	TGFBR1, TGFBR2	5.73
5	Marfan syndrome	Enrichment	TGFBR1, TGFBR2	4.08
6	Microform holoprosencephaly	Enrichment	CRIPTO, FGFR1	3.66
7	Lobar holoprosencephaly	Enrichment	CRIPTO, FGFR1	3.66
8	Semilobar holoprosencephaly	Enrichment	CRIPTO, FGFR1	3.55
9	Osteoglophonic dysplasia	Enrichment	FGFR1	2.85
10	Trigonocephaly 1	Enrichment	FGFR1	2.85
11	Fatal familial insomnia	Enrichment	PRNP	2.85
12	Gerstmann-straussler disease	Enrichment	PRNP	2.85
13	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	2.85
14	Kuru	Enrichment	PRNP	2.85
15	Spongiform encephalopathy with neuropsychiatric features	Enrichment	PRNP	2.85
16	Huntington disease-like 1	Enrichment	PRNP	2.85
17	Microvascular complications of diabetes 1	Enrichment	VEGFA	2.85
18	Cerebral amyloid angiopathy, app-related	Enrichment	APP	2.85
19	Antithrombin iii deficiency	Enrichment	SERPINC1	2.85
20	Colorectal cancer, hereditary nonpolyposis, type 6	Enrichment	TGFBR2	2.85
21	Familial alzheimer-like prion disease	Enrichment	PRNP	2.85
22	Loeys-dietz syndrome 6	Enrichment	SMAD2	2.85
23	Hartsfield syndrome	Enrichment	FGFR1	2.85
24	Prion disease	Enrichment	PRNP	2.85
25	Loeys-dietz syndrome 5	Enrichment	TGFB3	2.85
26	Immunodeficiency 22	Enrichment	LCK	2.85
27	Congenital heart defects, multiple types, 8, with or without heterotaxy	Enrichment	SMAD2	2.85
28	Prp systemic amyloidosis	Enrichment	PRNP	2.85
29	Inherited human prion disease	Enrichment	PRNP	2.85
30	Hartsfield-bixler-demyer syndrome	Enrichment	FGFR1	2.85
31	Inherited creutzfeldt-jakob disease	Enrichment	PRNP	2.85
32	Cerebral amyloid angiopathy, cst3-related	Enrichment	APP	2.55
33	Camurati-engelmann disease 1	Enrichment	TGFB1	2.55
34	Microvascular complications of diabetes 5	Enrichment	TGFBR2	2.55
35	Pfeiffer syndrome	Enrichment	FGFR1	2.55
36	Jackson-weiss syndrome	Enrichment	FGFR1	2.55
37	Encephalocraniocutaneous lipomatosis	Enrichment	FGFR1	2.55
38	Creutzfeldt-jakob disease	Enrichment	PRNP	2.55
39	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	2.55
40	Rosette-forming glioneuronal tumor	Enrichment	FGFR1	2.55
41	Camurati-engelmann disease	Enrichment	TGFB1	2.55
42	Loeys-dietz syndrome 4	Enrichment	TGFB3	2.55
43	Interfrontal craniofaciosynostosis	Enrichment	FGFR1	2.55
44	Hypogonadotropic hypogonadism 2 with or without anosmia	Enrichment	FGFR1	2.38
45	Chromosome 8p11 myeloproliferative syndrome	Enrichment	FGFR1	2.38
46	Poretti-boltshauser syndrome	Enrichment	LAMA1	2.38
47	Frontotemporal dementia 2	Enrichment	PRNP	2.25
48	Aortic aneurysm	Enrichment	TGFBR1	2.25
49	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	2.16
50	Pre-eclampsia	Enrichment	FLT1	2.16
51	Holoprosencephaly	Enrichment	FGFR1	2.16
52	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	2.16
53	Primary hypereosinophilic syndrome	Enrichment	FGFR1	2.16
54	Holoprosencephaly 1	Enrichment	FGFR1	2.08
55	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	2.08
56	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	2.08
57	Classic ehlers-danlos syndrome	Enrichment	TGFBR1	2.08
58	Esophageal cancer	Enrichment	TGFBR2	2.01
59	Alzheimer's disease 1	Enrichment	APP	2.01
60	Pilomyxoid astrocytoma	Enrichment	FGFR1	2.01
61	Early-onset autosomal dominant alzheimer disease	Enrichment	APP	2.01
62	Hypogonadotropic hypogonadism	Enrichment	FGFR1	1.90
63	Familial colorectal cancer	Enrichment	PLA2G2A	1.86
64	Pectus excavatum	Enrichment	TGFBR1	1.82
65	Septooptic dysplasia	Enrichment	FGFR1	1.78
66	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	TGFB3	1.78
67	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	TGFB3	1.78
68	Alzheimer's disease	Enrichment	APP	1.74
69	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	FGFR1	1.71
70	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	TGFB3	1.71
71	Lynch syndrome	Enrichment	TGFBR2	1.68
72	Septopreoptic holoprosencephaly	Enrichment	CRIPTO	1.68
73	Midline interhemispheric variant of holoprosencephaly	Enrichment	CRIPTO	1.68
74	Gliosarcoma	Enrichment	FGFR1	1.65
75	Alzheimer disease, familial, 1	Enrichment	APP	1.63
76	Giant cell glioblastoma	Enrichment	FGFR1	1.63
77	Alobar holoprosencephaly	Enrichment	CRIPTO	1.63
78	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	FGFR1	1.60
79	Ehlers-danlos syndrome	Enrichment	TGFBR2	1.58
80	Tooth agenesis	Enrichment	FGFR1	1.52
81	Kallmann syndrome	Enrichment	FGFR1	1.50
82	Cystic fibrosis	Enrichment	TGFB1	1.36
83	Connective tissue disease	Enrichment	TGFBR2	1.36
84	Severe combined immunodeficiency	Enrichment	LCK	1.34
85	Cakut	Enrichment	SLIT2	1.33
86	Colorectal cancer	Enrichment	PLA2G2A	0.94
87	Hereditary retinal dystrophy	Enrichment	LAMA1	0.47
88	Fundus dystrophy	Enrichment	LAMA1	0.47

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Glypican 1 network

Pathway Network for Glypican 1 network

Member Pathways for Glypican 1 network

Pathways in the Glypican 1 network SuperPath

Associated Genes for Glypican 1 network

Associated Disorders for Glypican 1 network

Disorders associated with Glypican 1 network SuperPath

STRING Interaction Network for Glypican 1 network

Sources for Glypican 1 network