GPCRs, class B secretin-like

No Pathway Network information available for GPCRs, class B secretin-like

#	Name	Source	Genes
1	GPCRs, class B secretin-like	WikiPathways	ADCYAP1R1 ADGRE1 ADGRE2 ADGRE5 ADGRG2 ADGRL1 ADGRL2 ADGRL3 ADGRL4 CALCR CALCRL CRHR1 CRHR2 GCGR GHRHR GIPR GLP1R GLP2R PTH1R PTH2R SCTR VIPR1 VIPR2 (see all 23) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GHRHR	Growth Hormone Releasing Hormone Receptor	Protein Coding	1
2	ADGRE5	Adhesion G Protein-Coupled Receptor E5	Protein Coding	1
3	CALCR	Calcitonin Receptor	Protein Coding	1
4	VIPR2	Vasoactive Intestinal Peptide Receptor 2	Protein Coding	1
5	VIPR1	Vasoactive Intestinal Peptide Receptor 1	Protein Coding	1
6	SCTR	Secretin Receptor	Protein Coding	1
7	PTH1R	Parathyroid Hormone 1 Receptor	Protein Coding	1
8	ADGRE2	Adhesion G Protein-Coupled Receptor E2	Protein Coding	1
9	GLP1R	Glucagon Like Peptide 1 Receptor	Protein Coding	1
10	GIPR	Gastric Inhibitory Polypeptide Receptor	Protein Coding	1
11	GCGR	Glucagon Receptor	Protein Coding	1
12	ADGRL3	Adhesion G Protein-Coupled Receptor L3	Protein Coding	1
13	ADGRE1	Adhesion G Protein-Coupled Receptor E1	Protein Coding	1
14	CRHR2	Corticotropin Releasing Hormone Receptor 2	Protein Coding	1
15	CRHR1	Corticotropin Releasing Hormone Receptor 1	Protein Coding	1
16	ADCYAP1R1	ADCYAP Receptor Type I	Protein Coding	1
17	CALCRL	Calcitonin Receptor Like Receptor	Protein Coding	1
18	ADGRG2	Adhesion G Protein-Coupled Receptor G2	Protein Coding	1
19	GLP2R	Glucagon Like Peptide 2 Receptor	Protein Coding	1
20	ADGRL4	Adhesion G Protein-Coupled Receptor L4	Protein Coding	1
21	PTH2R	Parathyroid Hormone 2 Receptor	Protein Coding	1
22	ADGRL2	Adhesion G Protein-Coupled Receptor L2	Protein Coding	1
23	ADGRL1	Adhesion G Protein-Coupled Receptor L1	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Vibratory urticaria	Enrichment	ADGRE2	2.77
2	Vas deferens, congenital bilateral aplasia of, x-linked	Enrichment	ADGRG2	2.77
3	Schizophrenia 16	Enrichment	VIPR2	2.77
4	Mahvash disease	Enrichment	GCGR	2.77
5	Isolated growth hormone deficiency, type iv	Enrichment	GHRHR	2.77
6	X-linked congenital bilateral absence of vas deferens	Enrichment	ADGRG2	2.77
7	Failure of tooth eruption, primary	Enrichment	PTH1R	2.47
8	Metaphyseal chondrodysplasia, jansen type	Enrichment	PTH1R	2.47
9	Chondrodysplasia, blomstrand type	Enrichment	PTH1R	2.47
10	Eiken syndrome	Enrichment	PTH1R	2.47
11	Pseudohypoparathyroidism	Enrichment	PTH1R	2.47
12	Developmental delay, behavioral abnormalities, and neuropsychiatric disorders	Enrichment	ADGRL1	2.47
13	Lymphatic malformation 8	Enrichment	CALCRL	2.47
14	Brachydactyly, type e1	Enrichment	PTH1R	2.29
15	Isolated growth hormone deficiency, type ib	Enrichment	GHRHR	2.29
16	Bone mineral density quantitative trait locus 15	Enrichment	CALCR	2.17
17	Enchondromatosis, multiple, ollier type	Enrichment	PTH1R	2.07
18	Vas deferens, congenital bilateral aplasia of	Enrichment	ADGRG2	1.82
19	Specific learning disability	Enrichment	ADGRL1	1.73
20	Osteoporosis	Enrichment	CALCR	1.63
21	Syndromic intellectual disability	Enrichment	PTH2R	1.55
22	Attention deficit-hyperactivity disorder	Enrichment	ADGRL1	1.44
23	Non-immune hydrops fetalis	Enrichment	CALCRL	1.29
24	Complex neurodevelopmental disorder	Enrichment	ADGRL1	0.72

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for GPCRs, class B secretin-like