Granzyme-A Pathway

No Pathway Network information available for Granzyme-A Pathway

#	Name	Source	Genes
1	Granzyme-A Pathway	QIAGEN	ANP32A APEX1 EP300 GZMA H1-0 H1-1 H1-10 H1-2 H1-3 H1-4 H1-5 H1-6 HMGB2 NME1 PRF1 SET (see all 16) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ANP32A	Acidic Nuclear Phosphoprotein 32 Family Member A	Protein Coding	1
2	APEX1	Apurinic/Apyrimidinic Endodeoxyribonuclease 1	Protein Coding	1
3	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
4	GZMA	Granzyme A	Protein Coding	1
5	H1-0	H1.0 Linker Histone	Protein Coding	1
6	H1-10	H1.10 Linker Histone	Protein Coding	1
7	H1-1	H1.1 Linker Histone, Cluster Member	Protein Coding	1
8	H1-5	H1.5 Linker Histone, Cluster Member	Protein Coding	1
9	H1-2	H1.2 Linker Histone, Cluster Member	Protein Coding	1
10	H1-3	H1.3 Linker Histone, Cluster Member	Protein Coding	1
11	H1-4	H1.4 Linker Histone, Cluster Member	Protein Coding	1
12	H1-6	H1.6 Linker Histone, Cluster Member	Protein Coding	1
13	HMGB2	High Mobility Group Box 2	Protein Coding	1
14	NME1	NME/NM23 Nucleoside Diphosphate Kinase 1	Protein Coding	1
15	PRF1	Perforin 1	Protein Coding	1
16	SET	SET Nuclear Proto-Oncogene	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hemophagocytic lymphohistiocytosis, familial, 2	Enrichment	PRF1	2.93
2	Rahman syndrome	Enrichment	H1-4	2.93
3	Fatal post-viral neurodegenerative disorder	Enrichment	PRF1	2.93
4	Menke-hennekam syndrome 2	Enrichment	EP300	2.63
5	Intellectual developmental disorder, autosomal dominant 58	Enrichment	SET	2.63
6	Hemophagocytic lymphohistiocytosis, familial, 1	Enrichment	PRF1	2.23
7	Rubinstein-taybi syndrome 2	Enrichment	EP300	2.23
8	Idiopathic aplastic anemia	Enrichment	PRF1	2.23
9	Rubinstein-taybi syndrome 1	Enrichment	EP300	2.15
10	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	EP300	2.15
11	Lymphoma, non-hodgkin, familial	Enrichment	PRF1	2.03
12	Charge syndrome	Enrichment	EP300	1.98
13	Aplastic anemia	Enrichment	PRF1	1.93
14	Polydactyly, postaxial, type a1	Enrichment	EP300	1.76
15	Rare genetic intellectual disability	Enrichment	EP300	1.76
16	Precursor t-cell acute lymphoblastic leukemia	Enrichment	SET	1.57
17	Autoinflammatory disease	Enrichment	PRF1	1.55
18	Auditory neuropathy	Enrichment	H1-4	1.52
19	Autosomal dominant non-syndromic intellectual disability	Enrichment	SET	1.24
20	Myeloma, multiple	Enrichment	H1-4	1.19
21	Colorectal cancer	Enrichment	EP300	1.01
22	Microcephaly	Enrichment	EP300	0.87

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Granzyme-A Pathway