H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity

No Pathway Network information available for H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity

Pathways in the H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity SuperPath

#	Name	Source	Genes
1	H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity	WikiPathways	CCND1 CDH1 CDK4 CDK8 CSRP2 CTNNB1 E2F1 JAG1 MACROH2A1 MED1 PMAIP1 RB1 SOX4 TULP3 (see all 14) (see less)
2	E-cadherin signaling events	PubChem	CDH1 CTNNB1

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CDH1	Cadherin 1	Protein Coding	2
2	CTNNB1	Catenin Beta 1	Protein Coding	2
3	TULP3	TUB Like Protein 3	Protein Coding	1
4	SOX4	SRY-Box Transcription Factor 4	Protein Coding	1
5	CCND1	Cyclin D1	Protein Coding	1
6	RB1	RB Transcriptional Corepressor 1	Protein Coding	1
7	MED1	Mediator Complex Subunit 1	Protein Coding	1
8	PMAIP1	Phorbol-12-Myristate-13-Acetate-Induced Protein 1	Protein Coding	1
9	E2F1	E2F Transcription Factor 1	Protein Coding	1
10	JAG1	Jagged Canonical Notch Ligand 1	Protein Coding	1
11	CSRP2	Cysteine And Glycine Rich Protein 2	Protein Coding	1
12	CDK4	Cyclin Dependent Kinase 4	Protein Coding	1
13	MACROH2A1	MacroH2A.1 Histone	Protein Coding	1
14	CDK8	Cyclin Dependent Kinase 8	Protein Coding	1

Disorders associated with H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Colorectal cancer	Enrichment	CDH1, CTNNB1	4.39
2	Ovarian cancer	Enrichment	CDH1, CTNNB1	4.26
3	Adenoid ameloblastoma	Enrichment	CTNNB1	3.83
4	Breast lobular carcinoma	Enrichment	CDH1	3.83
5	Microcystic stromal tumor	Enrichment	CTNNB1	3.83
6	Heart, malformation of	Enrichment	CDK8, JAG1	3.82
7	Hepatoblastoma	Enrichment	CTNNB1, JAG1	3.69
8	Blepharocheilodontic syndrome 1	Enrichment	CDH1	3.53
9	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	3.53
10	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	3.53
11	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	3.53
12	Teratoma	Enrichment	CTNNB1	3.53
13	Inherited cancer-predisposing syndrome	Enrichment	CDH1, CDK4, RB1	3.52
14	Bladder cancer	Enrichment	CTNNB1, RB1	3.40
15	Desmoid disease, hereditary	Enrichment	CTNNB1	3.35
16	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	3.35
17	Anus, imperforate	Enrichment	CTNNB1	3.35
18	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	3.35
19	Desmoid tumor	Enrichment	CTNNB1	3.35
20	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CDH1	3.23
21	Pilomatrixoma	Enrichment	CTNNB1	3.23
22	Alazami syndrome	Enrichment	CTNNB1	3.23
23	Craniopharyngioma	Enrichment	CTNNB1	3.23
24	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	3.13
25	Gastric cancer	Enrichment	CDH1, CDK4	3.06
26	Weyers acrofacial dysostosis	Enrichment	CTNNB1	3.05
27	Adrenocortical carcinoma	Enrichment	CTNNB1	3.05
28	Cleft lip with or without cleft palate	Enrichment	CDH1	3.05
29	Gallbladder cancer	Enrichment	CTNNB1	2.99
30	Melanoma, cutaneous malignant 3	Enrichment	CDK4	2.99
31	Intellectual developmental disorder with speech delay and dysmorphic facies	Enrichment	SOX4	2.99
32	Charcot-marie-tooth disease, axonal, type 2hh	Enrichment	JAG1	2.99
33	Hepatorenocardiac degenerative fibrosis	Enrichment	TULP3	2.99
34	Deafness, congenital heart defects, and posterior embryotoxon	Enrichment	JAG1	2.99
35	Trilateral retinoblastoma	Enrichment	RB1	2.99
36	Lung oat cell carcinoma	Enrichment	RB1	2.99
37	Exudative vitreoretinopathy	Enrichment	CTNNB1	2.93
38	Adult hepatocellular carcinoma	Enrichment	CTNNB1	2.88
39	Ebstein anomaly	Enrichment	CDK8	2.69
40	Chromosome 13q14 deletion syndrome	Enrichment	RB1	2.69
41	Intellectual developmental disorder with hypotonia and behavioral abnormalities	Enrichment	CDK8	2.69
42	Brachydactyly-elbow wrist dysplasia syndrome	Enrichment	MACROH2A1	2.69
43	Familial retinoblastoma	Enrichment	RB1	2.69
44	Medulloblastoma	Enrichment	CTNNB1	2.69
45	Cleft lip/palate	Enrichment	CDH1	2.69
46	Polycystic liver disease	Enrichment	CTNNB1	2.60
47	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	2.60
48	Retinoblastoma	Enrichment	RB1	2.51
49	Alagille syndrome 1	Enrichment	JAG1	2.51
50	Osteogenic sarcoma	Enrichment	RB1	2.51
51	Woolly hair, autosomal recessive 3	Enrichment	RB1	2.51
52	Hypotrichosis 8	Enrichment	RB1	2.51
53	Dedifferentiated liposarcoma	Enrichment	CDK4	2.51
54	Squamous cell carcinoma	Enrichment	RB1	2.51
55	Bone osteosarcoma	Enrichment	RB1	2.51
56	Well-differentiated liposarcoma	Enrichment	CDK4	2.51
57	Endometrial cancer	Enrichment	CDH1	2.51
58	Hepatocellular carcinoma	Enrichment	CTNNB1	2.49
59	Small cell cancer of the lung	Enrichment	RB1	2.38
60	Lynch syndrome 4	Enrichment	RB1	2.38
61	Mantle cell lymphoma	Enrichment	CCND1	2.38
62	Middle aortic syndrome	Enrichment	JAG1	2.38
63	Prostate cancer	Enrichment	CDH1	2.37
64	Von hippel-lindau syndrome	Enrichment	CCND1	2.29
65	Hereditary breast carcinoma	Enrichment	CDH1	2.19
66	Leukemia, chronic lymphocytic	Enrichment	CCND1	1.99
67	Breast cancer	Enrichment	CDH1	1.96
68	Lip and oral cavity carcinoma	Enrichment	RB1	1.91
69	Diaphragmatic hernia, congenital	Enrichment	CDK8	1.87
70	Lung cancer susceptibility 3	Enrichment	RB1	1.84
71	Coffin-siris syndrome 1	Enrichment	SOX4	1.81
72	Congenital nervous system abnormality	Enrichment	CTNNB1	1.81
73	Nervous system disease	Enrichment	CTNNB1	1.81
74	Hydrocephalus, congenital, 1	Enrichment	CDK8	1.79
75	Melanoma, cutaneous malignant 1	Enrichment	CDK4	1.76
76	Microcephaly	Enrichment	CTNNB1	1.74
77	Tetralogy of fallot	Enrichment	JAG1	1.58
78	Myeloma, multiple	Enrichment	CCND1	1.25
79	Complex neurodevelopmental disorder	Enrichment	CDK8	0.92
80	Hereditary retinal dystrophy	Enrichment	JAG1	0.58
81	Fundus dystrophy	Enrichment	JAG1	0.58

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity

Pathway Network for H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity

Member Pathways for H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity

Pathways in the H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity SuperPath

Associated Genes for H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity

Associated Disorders for H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity

Disorders associated with H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity SuperPath

STRING Interaction Network for H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity

Sources for H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity