Hair follicle development: organogenesis - part 2 of 3

No Pathway Network information available for Hair follicle development: organogenesis - part 2 of 3

Pathways in the Hair follicle development: organogenesis - part 2 of 3 SuperPath

#	Name	Source	Genes
1	Hair follicle development: organogenesis - part 2 of 3	WikiPathways	BMP4 CCND1 CCND2 EDA EDAR FGF1 FGFR2 FZD1 GLI1 GLI2 GTPBP4 ITGB1 LAMA5 LEF1 LRP5 MYC NCAM1 NFKB1 PDGFA PDGFRA PTCH1 SHH SMO SNAI1 WNT5A (see all 25) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GTPBP4	GTP Binding Protein 4	Protein Coding	1
2	FZD1	Frizzled Class Receptor 1	Protein Coding	1
3	FGF1	Fibroblast Growth Factor 1	Protein Coding	1
4	SHH	Sonic Hedgehog Signaling Molecule	Protein Coding	1
5	BMP4	Bone Morphogenetic Protein 4	Protein Coding	1
6	PDGFA	Platelet Derived Growth Factor Subunit A	Protein Coding	1
7	LEF1	Lymphoid Enhancer Binding Factor 1	Protein Coding	1
8	EDA	Ectodysplasin A	Protein Coding	1
9	EDAR	Ectodysplasin A Receptor	Protein Coding	1
10	LRP5	LDL Receptor Related Protein 5	Protein Coding	1
11	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	1
12	CCND2	Cyclin D2	Protein Coding	1
13	GLI1	GLI Family Zinc Finger 1	Protein Coding	1
14	GLI2	GLI Family Zinc Finger 2	Protein Coding	1
15	PTCH1	Patched 1	Protein Coding	1
16	WNT5A	Wnt Family Member 5A	Protein Coding	1
17	CCND1	Cyclin D1	Protein Coding	1
18	SMO	Smoothened, Frizzled Class Receptor	Protein Coding	1
19	PDGFRA	Platelet Derived Growth Factor Receptor Alpha	Protein Coding	1
20	LAMA5	Laminin Subunit Alpha 5	Protein Coding	1
21	SNAI1	Snail Family Transcriptional Repressor 1	Protein Coding	1
22	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	1
23	ITGB1	Integrin Subunit Beta 1	Protein Coding	1
24	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
25	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1

Disorders associated with Hair follicle development: organogenesis - part 2 of 3 SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Septopreoptic holoprosencephaly	Enrichment	GLI2, PTCH1, SHH	5.61
2	Midline interhemispheric variant of holoprosencephaly	Enrichment	GLI2, PTCH1, SHH	5.61
3	Microform holoprosencephaly	Enrichment	GLI2, PTCH1, SHH	5.52
4	Lobar holoprosencephaly	Enrichment	GLI2, PTCH1, SHH	5.52
5	Split hand-foot malformation	Enrichment	FGFR2, LEF1	5.49
6	Alobar holoprosencephaly	Enrichment	GLI2, PTCH1, SHH	5.43
7	Semilobar holoprosencephaly	Enrichment	GLI2, PTCH1, SHH	5.35
8	Polydactyly, preaxial ii	Enrichment	PTCH1, SHH	4.71
9	Ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	EDA, EDAR	4.71
10	Ectodermal dysplasia	Enrichment	EDA, EDAR	4.71
11	Split-hand/foot malformation 1	Enrichment	FGFR2, LEF1	4.31
12	Cleft lip/palate	Enrichment	BMP4, PDGFRA	3.53
13	Polydactyly, postaxial, type a1	Enrichment	GLI1, PTCH1	3.47
14	Macs syndrome	Enrichment	PTCH1, SHH	3.22
15	Craniosynostosis	Enrichment	FGFR2, GLI2	3.22
16	Tooth agenesis	Enrichment	EDA, EDAR	3.13
17	Holoprosencephaly 3	Enrichment	SHH	2.73
18	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	2.73
19	Endosteal hyperostosis, autosomal dominant	Enrichment	LRP5	2.73
20	Bone mineral density quantitative trait locus 1	Enrichment	LRP5	2.73
21	Exudative vitreoretinopathy 4	Enrichment	LRP5	2.73
22	Curry-jones syndrome	Enrichment	SMO	2.73
23	Hypereosinophilic syndrome, idiopathic	Enrichment	PDGFRA	2.73
24	Schilbach-rott syndrome	Enrichment	PTCH1	2.73
25	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	2.73
26	Apert syndrome	Enrichment	FGFR2	2.73
27	Microphthalmia/coloboma 5	Enrichment	SHH	2.73
28	Polydactyly, preaxial i	Enrichment	GLI1	2.73
29	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3	Enrichment	CCND2	2.73
30	Gist-plus syndrome	Enrichment	PDGFRA	2.73
31	Culler-jones syndrome	Enrichment	GLI2	2.73
32	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	2.73
33	Ectodermal dysplasia 17 with or without limb malformations	Enrichment	LEF1	2.73
34	Nephrotic syndrome, type 26	Enrichment	LAMA5	2.73
35	Polydactyly, postaxial, type a8	Enrichment	GLI1	2.73
36	Microphthalmia, syndromic 6	Enrichment	BMP4	2.73
37	Myeloid and lymphoid neoplasms associated with pdgfra rearrangement	Enrichment	PDGFRA	2.73
38	Orofacial cleft 11	Enrichment	BMP4	2.73
39	Tooth agenesis, selective, x-linked, 1	Enrichment	EDA	2.73
40	Osteoporosis-pseudoglioma syndrome	Enrichment	LRP5	2.73
41	Polycystic liver disease 4 with or without kidney cysts	Enrichment	LRP5	2.73
42	Hair morphology 1	Enrichment	EDAR	2.73
43	Holoprosencephaly 9	Enrichment	GLI2	2.73
44	Bent bone dysplasia syndrome 2	Enrichment	LAMA5	2.73
45	Lrp5-related primary osteoporosis	Enrichment	LRP5	2.73
46	Turner syndrome	Enrichment	PTCH1	2.73
47	Monosomy 9q22.3	Enrichment	PTCH1	2.73
48	Osteosclerosis-developmental delay-craniosynostosis syndrome	Enrichment	LRP5	2.73
49	Postaxial polydactyly-anterior pituitary anomalies-facial dysmorphism syndrome	Enrichment	GLI2	2.73
50	Lama5-related multisystemic syndrome	Enrichment	LAMA5	2.73
51	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	2.73
52	Autosomal dominant preaxial polydactyly-upperback hypertrichosis syndrome	Enrichment	SHH	2.73
53	Ectrodactyly and ectodermal dysplasia without cleft lip/palate	Enrichment	LEF1	2.43
54	Burkitt lymphoma	Enrichment	MYC	2.43
55	Van buchem disease	Enrichment	LRP5	2.43
56	Pallister-hall-like syndrome	Enrichment	SMO	2.43
57	Aural atresia, congenital	Enrichment	FGFR2	2.43
58	Pfeiffer syndrome	Enrichment	FGFR2	2.43
59	Jackson-weiss syndrome	Enrichment	FGFR2	2.43
60	Solitary median maxillary central incisor	Enrichment	SHH	2.43
61	White-sutton syndrome	Enrichment	GLI2	2.43
62	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.43
63	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	2.43
64	Ectodermal dysplasia 1, hypohidrotic, x-linked	Enrichment	EDA	2.43
65	Postaxial polydactyly type b	Enrichment	GLI1	2.43
66	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	2.43
67	Chronic eosinophilic leukemia	Enrichment	PDGFRA	2.43
68	B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality	Enrichment	PDGFRA	2.43
69	Osteosclerosis	Enrichment	LRP5	2.43
70	Common variable immunodeficiency 12	Enrichment	NFKB1	2.43
71	Isolated radial hemimelia	Enrichment	SHH	2.43
72	Crouzon syndrome	Enrichment	FGFR2	2.26
73	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGFR2	2.26
74	Syndactyly, type iv	Enrichment	SHH	2.26
75	Tooth agenesis, selective, 2	Enrichment	EDA	2.26
76	Osteopetrosis, autosomal dominant 1	Enrichment	LRP5	2.26
77	Holoprosencephaly 7	Enrichment	PTCH1	2.26
78	Ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	EDAR	2.26
79	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	2.26
80	Hypoplastic or aplastic tibia with polydactyly	Enrichment	SHH	2.26
81	Robinow syndrome, autosomal dominant 1	Enrichment	WNT5A	2.13
82	Schizencephaly	Enrichment	SHH	2.13
83	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	CCND2	2.13
84	Saethre-chotzen syndrome	Enrichment	FGFR2	2.13
85	Mantle cell lymphoma	Enrichment	CCND1	2.13
86	Retinopathy of prematurity	Enrichment	LRP5	2.13
87	Autosomal dominant robinow syndrome	Enrichment	WNT5A	2.13
88	Glioma	Enrichment	FGFR2	2.13
89	Vitreoretinopathy	Enrichment	LRP5	2.13
90	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	EDAR	2.04
91	Hemifacial hyperplasia	Enrichment	FGFR2	2.04
92	Exudative vitreoretinopathy 1	Enrichment	LRP5	2.04
93	Von hippel-lindau syndrome	Enrichment	CCND1	2.04
94	Robinow syndrome, autosomal recessive 1	Enrichment	WNT5A	2.04
95	Autosomal recessive hypohidrotic ectodermal dysplasia syndrome	Enrichment	EDAR	2.04
96	Primary hypereosinophilic syndrome	Enrichment	PDGFRA	2.04
97	Basal cell nevus syndrome 1	Enrichment	PTCH1	1.96
98	Anterior segment dysgenesis 5	Enrichment	BMP4	1.96
99	Basal cell carcinoma 1	Enrichment	PTCH1	1.96
100	Autosomal recessive robinow syndrome	Enrichment	WNT5A	1.96
101	Colorectal cancer	Enrichment	CCND1, FGFR2	1.96
102	Mitochondrial dna depletion syndrome 4a	Enrichment	EDAR	1.89
103	Gastrointestinal stromal tumor	Enrichment	PDGFRA	1.89
104	Common variable immunodeficiency	Enrichment	NFKB1	1.89
105	Congenital hydrocephalus	Enrichment	PTCH1	1.89
106	Overgrowth syndrome	Enrichment	PTCH1	1.89
107	Mitochondrial dna depletion syndrome 4b	Enrichment	EDAR	1.83
108	Exudative vitreoretinopathy	Enrichment	LRP5	1.83
109	Combined pituitary hormone deficiency	Enrichment	GLI2	1.83
110	Ovarian cancer	Enrichment	PDGFRA, PTCH1	1.83
111	Tooth agenesis, selective, 1	Enrichment	EDA	1.78
112	Ellis-van creveld syndrome	Enrichment	GLI1	1.78
113	Leukemia, chronic lymphocytic	Enrichment	CCND1	1.74
114	Meier-gorlin syndrome 1	Enrichment	FGFR2	1.74
115	Peters-plus syndrome	Enrichment	BMP4	1.74
116	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.74
117	Stickler syndrome	Enrichment	BMP4	1.74
118	Presynaptic congenital myasthenic syndromes	Enrichment	LAMA5	1.70
119	Septooptic dysplasia	Enrichment	SHH	1.66
120	Renal hypodysplasia/aplasia 3	Enrichment	BMP4	1.66
121	Meningioma	Enrichment	SMO	1.66
122	Neural tube defects	Enrichment	ITGB1	1.63
123	Inherited cancer-predisposing syndrome	Enrichment	PDGFRA, PTCH1	1.61
124	Multiple sclerosis	Enrichment	LAMA5	1.59
125	Osteoporosis	Enrichment	LRP5	1.59
126	Medulloblastoma	Enrichment	PTCH1	1.59
127	Hydrocephalus	Enrichment	FGFR2	1.56
128	Rhabdomyosarcoma	Enrichment	PTCH1	1.54
129	Polycystic liver disease	Enrichment	LRP5	1.51
130	Autosomal dominant polycystic liver disease	Enrichment	LRP5	1.51
131	Endometrial cancer	Enrichment	FGFR2	1.42
132	Microphthalmia	Enrichment	PTCH1	1.40
133	Brittle bone disorder	Enrichment	LRP5	1.38
134	Precursor t-cell acute lymphoblastic leukemia	Enrichment	MYC	1.38
135	Hirschsprung disease 1	Enrichment	SMO	1.28
136	Genetic steroid-resistant nephrotic syndrome	Enrichment	LAMA5	1.22
137	Gastric cancer	Enrichment	FGFR2	1.12
138	Nephrotic syndrome	Enrichment	LAMA5	1.12
139	Hypertelorism	Enrichment	FGFR2	1.04
140	Hereditary breast ovarian cancer syndrome	Enrichment	PTCH1	1.01
141	Myeloma, multiple	Enrichment	CCND1	1.01
142	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	GLI2	1.01
143	Autism	Enrichment	SHH	0.90
144	Hereditary retinal dystrophy	Enrichment	LRP5	0.38
145	Fundus dystrophy	Enrichment	LRP5	0.38

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Hair follicle development: organogenesis - part 2 of 3

Pathway Network for Hair follicle development: organogenesis - part 2 of 3

Member Pathways for Hair follicle development: organogenesis - part 2 of 3

Pathways in the Hair follicle development: organogenesis - part 2 of 3 SuperPath

Associated Genes for Hair follicle development: organogenesis - part 2 of 3

Associated Disorders for Hair follicle development: organogenesis - part 2 of 3

Disorders associated with Hair follicle development: organogenesis - part 2 of 3 SuperPath

STRING Interaction Network for Hair follicle development: organogenesis - part 2 of 3

Sources for Hair follicle development: organogenesis - part 2 of 3