HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

Pathway network for the HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) SuperPath

Sources:

Reactome

Pathways in the HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) SuperPath

#	Name	Source	Genes
1	HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	Reactome	ABL1 ABRAXAS1 ATM ATR ATRIP BABAM1 BABAM2 BARD1 BLM BRCA1 BRCA2 BRCC3 BRIP1 CCNA1 CCNA2 CDK2 CHEK1 CLSPN DNA2 EME1 EME2 ERCC1 ERCC4 EXO1 FIGNL1 FIRRM GEN1 H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-4 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HERC2 HUS1 KAT5 MDC1 MRE11 MUS81 NBN NSD2 PALB2 PCNA PIAS4 POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLH POLK PPP4C PPP4R2 RAD1 RAD17 RAD50 RAD51 RAD51AP1 RAD51B RAD51C RAD51D RAD52 RAD9A RAD9B RBBP8 RFC1 RFC2 RFC3 RFC4 RFC5 RHNO1 RMI1 RMI2 RNF168 RNF4 RNF8 RPA1 RPA2 RPA3 RPS27A RTEL1 SEM1 SIRT6 SLX1A SLX1B SLX4 SPIDR SUMO2 TIMELESS TIPIN TOP3A TOPBP1 TP53BP1 UBA52 UBB UBC UBE2I UBE2N UBE2V2 UIMC1 WRN XRCC2 XRCC3 (see all 134) (see less)
2	DNA Repair	Reactome	ABL1 ABRAXAS1 ACD ACTB ACTL6A ACTR5 ACTR8 ADPRS ALKBH2 ALKBH3 ALKBH5 APBB1 APEX1 AQR ASCC1 ASCC2 ASCC3 ATM ATR ATRIP BABAM1 BABAM2 BAP1 BARD1 BAZ1B BLM BRCA1 BRCA2 BRCC3 BRIP1 CCNA1 CCNA2 CCNH CDK2 CDK7 CENPS CENPS-CORT CENPX CETN2 CHD1L CHEK1 CHEK2 CLSPN COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 CUL4A CUL4B DCLRE1A DCLRE1B DCLRE1C DDB1 DDB2 DNA2 DTL ELL EME1 EME2 ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 ERCC6 ERCC8 EXO1 EYA1 EYA2 EYA3 EYA4 FAAP100 FAAP20 FAAP24 FAN1 FANCA FANCB FANCC FANCD2 FANCE FANCF FANCG FANCI FANCL FANCM FEN1 FIGNL1 FIRRM FTO GEN1 GPS1 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AJ H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-4 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HERC2 HUS1 INO80 INO80B INO80C INO80D INO80E ISG15 ISY1 ISY1-RAB43 KAT5 KDM4A KDM4B KPNA2 LIG1 LIG3 LIG4 MAD2L2 MAPK8 MBD4 MCRS1 MDC1 MGMT MLH1 MNAT1 MPG MRE11 MSH2 MSH3 MSH6 MUS81 MUTYH NBN NEIL1 NEIL2 NEIL3 NFRKB NHEJ1 NPLOC4 NSD2 NTHL1 OGG1 PALB2 PARG PARP1 PARP2 PAXIP1 PCLAF PCNA PIAS1 PIAS3 PIAS4 PMS2 PNKP POLB POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLH POLI POLK POLL POLM POLN POLQ POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L POT1 PPIE PPP4C PPP4R2 PPP5C PRKDC PRPF19 RAD1 RAD17 RAD18 RAD23A RAD23B RAD50 RAD51 RAD51AP1 RAD51B RAD51C RAD51D RAD52 RAD9A RAD9B RBBP8 RBX1 RCHY1 REV1 REV3L RFC1 RFC2 RFC3 RFC4 RFC5 RHNO1 RIF1 RMI1 RMI2 RNF111 RNF168 RNF4 RNF8 RPA1 RPA2 RPA3 RPS27A RTEL1 RUVBL1 SEM1 SIRT6 SLX1A SLX1B SLX4 SMARCA5 SMUG1 SPIDR SPRTN SUMO1 SUMO2 SUMO3 TCEA1 TDG TDP1 TDP2 TERF1 TERF2 TERF2IP TFPT TIMELESS TINF2 TIPIN TOP3A TOPBP1 TP53 TP53BP1 TRIM25 UBA52 UBA7 UBB UBC UBE2B UBE2I UBE2L6 UBE2N UBE2T UBE2V2 UBXN1 UFD1 UIMC1 UNG USP1 USP10 USP43 USP45 USP7 UVSSA VCP WDR48 WRN XAB2 XPA XPC XRCC1 XRCC2 XRCC3 XRCC4 XRCC5 XRCC6 YY1 ZNF830 (see all 334) (see less)
3	Cell Cycle Checkpoints	Reactome	ABRAXAS1 ADRM1 AHCTF1 ANAPC1 ANAPC10 ANAPC11 ANAPC15 ANAPC16 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ATM ATR ATRIP AURKB B9D2 BABAM1 BABAM2 BARD1 BIRC5 BLM BRCA1 BRCC3 BRIP1 BTRC BUB1 BUB1B BUB3 CCNA1 CCNA2 CCNB1 CCNB2 CCNE1 CCNE2 CDC16 CDC20 CDC23 CDC25A CDC25C CDC26 CDC27 CDC45 CDC6 CDC7 CDCA8 CDK1 CDK2 CDKN1A CDKN1B CDKN2A CENPA CENPC CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPS CENPS-CORT CENPT CENPU CHEK1 CHEK2 CKAP5 CLASP1 CLASP2 CLIP1 CLSPN COP1 CUL1 DBF4 DNA2 DSN1 DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ERCC6L EXO1 FBXW11 GTSE1 H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-4 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HERC2 HUS1 INCENP ITGB3BP KAT5 KIF18A KIF2A KIF2B KIF2C KNL1 KNTC1 MAD1L1 MAD2L1 MAPRE1 MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 MDC1 MDM2 MDM4 MIS12 MRE11 NBN NDC80 NDE1 NDEL1 NSD2 NSL1 NUDC NUF2 NUP107 NUP133 NUP160 NUP37 NUP43 NUP85 NUP98 ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 PAFAH1B1 PCBP4 PHF20 PIAS4 PKMYT1 PLK1 PMF1 PMF1-BGLAP PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RAD1 RAD17 RAD50 RAD9A RAD9B RANBP2 RANGAP1 RBBP8 RBX1 RCC2 RFC2 RFC3 RFC4 RFC5 RHNO1 RMI1 RMI2 RNF168 RNF8 RPA1 RPA2 RPA3 RPS27 RPS27A SEC13 SEH1L SEM1 SFN SGO1 SGO2 SKA1 SKA2 SKP1 SPC24 SPC25 SPDL1 TAOK1 TOP3A TOPBP1 TP53 TP53BP1 UBA52 UBB UBC UBE2C UBE2D1 UBE2E1 UBE2N UBE2S UBE2V2 UIMC1 WEE1 WRN XPO1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ ZNF385A ZW10 ZWILCH ZWINT (see all 285) (see less)
4	DNA Double-Strand Break Repair	Reactome	ABL1 ABRAXAS1 APBB1 ATM ATR ATRIP BABAM1 BABAM2 BAP1 BARD1 BAZ1B BLM BRCA1 BRCA2 BRCC3 BRIP1 CCNA1 CCNA2 CDK2 CHEK1 CHEK2 CLSPN DCLRE1C DNA2 EME1 EME2 ERCC1 ERCC4 EXO1 EYA1 EYA2 EYA3 EYA4 FEN1 FIGNL1 FIRRM GEN1 H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-4 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HERC2 HUS1 KAT5 KDM4A KDM4B KPNA2 LIG3 LIG4 MAPK8 MDC1 MRE11 MUS81 NBN NHEJ1 NSD2 PALB2 PARP1 PARP2 PAXIP1 PCNA PIAS4 POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLH POLK POLL POLM POLQ PPP4C PPP4R2 PPP5C PRKDC RAD1 RAD17 RAD50 RAD51 RAD51AP1 RAD51B RAD51C RAD51D RAD52 RAD9A RAD9B RBBP8 RFC1 RFC2 RFC3 RFC4 RFC5 RHNO1 RIF1 RMI1 RMI2 RNF168 RNF4 RNF8 RPA1 RPA2 RPA3 RPS27A RTEL1 SEM1 SIRT6 SLX1A SLX1B SLX4 SMARCA5 SPIDR SUMO1 SUMO2 TDP1 TDP2 TIMELESS TIPIN TOP3A TOPBP1 TP53 TP53BP1 UBA52 UBB UBC UBE2I UBE2N UBE2V2 UBXN1 UIMC1 WRN XRCC1 XRCC2 XRCC3 XRCC4 XRCC5 XRCC6 (see all 170) (see less)
5	G2/M Checkpoints	Reactome	ABRAXAS1 ADRM1 ATM ATR ATRIP BABAM1 BABAM2 BARD1 BLM BRCA1 BRCC3 BRIP1 CCNA1 CCNA2 CCNB1 CCNB2 CDC25A CDC25C CDC45 CDC6 CDC7 CDK1 CDK2 CHEK1 CHEK2 CLSPN DBF4 DNA2 EXO1 GTSE1 H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-4 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HERC2 HUS1 KAT5 MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 MDC1 MRE11 NBN NSD2 ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 PIAS4 PKMYT1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RAD1 RAD17 RAD50 RAD9A RAD9B RBBP8 RFC2 RFC3 RFC4 RFC5 RHNO1 RMI1 RMI2 RNF168 RNF8 RPA1 RPA2 RPA3 RPS27A SEM1 SFN TOP3A TOPBP1 TP53 TP53BP1 UBA52 UBB UBC UBE2N UBE2V2 UIMC1 WEE1 WRN YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 156) (see less)
6	Homology Directed Repair	Reactome	ABL1 ABRAXAS1 ATM ATR ATRIP BABAM1 BABAM2 BARD1 BLM BRCA1 BRCA2 BRCC3 BRIP1 CCNA1 CCNA2 CDK2 CHEK1 CLSPN DNA2 EME1 EME2 ERCC1 ERCC4 EXO1 FEN1 FIGNL1 FIRRM GEN1 H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-4 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HERC2 HUS1 KAT5 LIG3 MDC1 MRE11 MUS81 NBN NSD2 PALB2 PARP1 PARP2 PCNA PIAS4 POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLH POLK POLQ PPP4C PPP4R2 RAD1 RAD17 RAD50 RAD51 RAD51AP1 RAD51B RAD51C RAD51D RAD52 RAD9A RAD9B RBBP8 RFC1 RFC2 RFC3 RFC4 RFC5 RHNO1 RMI1 RMI2 RNF168 RNF4 RNF8 RPA1 RPA2 RPA3 RPS27A RTEL1 SEM1 SIRT6 SLX1A SLX1B SLX4 SPIDR SUMO2 TIMELESS TIPIN TOP3A TOPBP1 TP53BP1 UBA52 UBB UBC UBE2I UBE2N UBE2V2 UIMC1 WRN XRCC1 XRCC2 XRCC3 (see all 140) (see less)
7	Processing of DNA double-strand break ends	Reactome	ABRAXAS1 ATM ATR ATRIP BABAM1 BABAM2 BARD1 BLM BRCA1 BRCC3 BRIP1 CCNA1 CCNA2 CDK2 CHEK1 CLSPN DNA2 EXO1 H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-4 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HERC2 HUS1 KAT5 MDC1 MRE11 NBN NSD2 PIAS4 PPP4C PPP4R2 RAD1 RAD17 RAD50 RAD9A RAD9B RBBP8 RFC2 RFC3 RFC4 RFC5 RHNO1 RMI1 RMI2 RNF168 RNF4 RNF8 RPA1 RPA2 RPA3 RPS27A SIRT6 SUMO2 TIMELESS TIPIN TOP3A TOPBP1 TP53BP1 UBA52 UBB UBC UBE2I UBE2N UBE2V2 UIMC1 WRN (see all 97) (see less)
8	G2/M DNA damage checkpoint	Reactome	ABRAXAS1 ATM ATR ATRIP BABAM1 BABAM2 BARD1 BLM BRCA1 BRCC3 BRIP1 CCNA1 CCNA2 CCNB1 CDC25C CDK1 CHEK1 CHEK2 DNA2 EXO1 H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-4 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HERC2 HUS1 KAT5 MDC1 MRE11 NBN NSD2 PIAS4 RAD1 RAD17 RAD50 RAD9A RAD9B RBBP8 RFC2 RFC3 RFC4 RFC5 RHNO1 RMI1 RMI2 RNF168 RNF8 RPA1 RPA2 RPA3 SFN TOP3A TOPBP1 TP53 TP53BP1 UBE2N UBE2V2 UIMC1 WEE1 WRN YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 96) (see less)
9	Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	Reactome	CCNA1 CCNA2 CCNB1 CDC25C CDK1 CHEK1 CHEK2 SFN WEE1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 15) (see less)
10	HDR through MMEJ (alt-NHEJ)	Reactome	BRCA2 FEN1 LIG3 MRE11 NBN PARP1 PARP2 POLQ RAD50 RAD52 RBBP8 XRCC1 (see all 12) (see less)

Gene overlap in member pathways for HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RAD50	RAD50 Double Strand Break Repair Protein	Protein Coding	9
2	CHEK1	Checkpoint Kinase 1	Protein Coding	9
3	MRE11	MRE11 Double Strand Break Repair Nuclease	Protein Coding	9
4	NBN	Nibrin	Protein Coding	9
5	RBBP8	RB Binding Protein 8, Endonuclease	Protein Coding	9
6	CCNA2	Cyclin A2	Protein Coding	9
7	CCNA1	Cyclin A1	Protein Coding	9
8	KAT5	Lysine Acetyltransferase 5	Protein Coding	8
9	TOPBP1	DNA Topoisomerase II Binding Protein 1	Protein Coding	8
10	RMI2	RecQ Mediated Genome Instability 2	Protein Coding	8
11	H4C16	H4 Histone 16	Protein Coding	8
12	H2BC26	H2B Clustered Histone 26	Protein Coding	8
13	RAD9B	RAD9 Checkpoint Clamp Component B	Protein Coding	8
14	RNF168	Ring Finger Protein 168	Protein Coding	8
15	DNA2	DNA Replication Helicase/Nuclease 2	Protein Coding	8
16	H2BC1	H2B Clustered Histone 1	Protein Coding	8
17	BABAM1	BRISC And BRCA1 A Complex Member 1	Protein Coding	8
18	H2AX	H2A.X Variant Histone	Protein Coding	8
19	H2BC5	H2B Clustered Histone 5	Protein Coding	8
20	H2BC3	H2B Clustered Histone 3	Protein Coding	8
21	HUS1	HUS1 Checkpoint Clamp Component	Protein Coding	8
22	ATM	ATM Serine/Threonine Kinase	Protein Coding	8
23	PIAS4	Protein Inhibitor Of Activated STAT 4	Protein Coding	8
24	UIMC1	Ubiquitin Interaction Motif Containing 1	Protein Coding	8
25	H2BC12L	H2B Clustered Histone 12 Like	Protein Coding	8
26	ATR	ATR Checkpoint Kinase	Protein Coding	8
27	H4C15	H4 Clustered Histone 15	Protein Coding	8
28	BARD1	BRCA1 Associated RING Domain 1	Protein Coding	8
29	RAD1	RAD1 Checkpoint DNA Exonuclease	Protein Coding	8
30	RAD9A	RAD9 Checkpoint Clamp Component A	Protein Coding	8
31	RAD17	RAD17 Checkpoint Clamp Loader Component	Protein Coding	8
32	RFC2	Replication Factor C Subunit 2	Protein Coding	8
33	RFC3	Replication Factor C Subunit 3	Protein Coding	8
34	RFC4	Replication Factor C Subunit 4	Protein Coding	8
35	RFC5	Replication Factor C Subunit 5	Protein Coding	8
36	RPA1	Replication Protein A1	Protein Coding	8
37	RPA2	Replication Protein A2	Protein Coding	8
38	RPA3	Replication Protein A3	Protein Coding	8
39	BLM	BLM RecQ Like Helicase	Protein Coding	8
40	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	8
41	TOP3A	DNA Topoisomerase III Alpha	Protein Coding	8
42	TP53BP1	Tumor Protein P53 Binding Protein 1	Protein Coding	8
43	UBE2N	Ubiquitin Conjugating Enzyme E2 N	Protein Coding	8
44	UBE2V2	Ubiquitin Conjugating Enzyme E2 V2	Protein Coding	8
45	NSD2	Nuclear Receptor Binding SET Domain Protein 2	Protein Coding	8
46	WRN	WRN RecQ Like Helicase	Protein Coding	8
47	BRCC3	BRCA1/BRCA2-Containing Complex Subunit 3	Protein Coding	8
48	RMI1	RecQ Mediated Genome Instability 1	Protein Coding	8
49	H3-4	H3.4 Histone, Cluster Member	Protein Coding	8
50	H4C9	H4 Clustered Histone 9	Protein Coding	8
51	H2BC8	H2B Clustered Histone 8	Protein Coding	8
52	H2BC13	H2B Clustered Histone 13	Protein Coding	8
53	H2BC15	H2B Clustered Histone 15	Protein Coding	8
54	H2BC14	H2B Clustered Histone 14	Protein Coding	8
55	H2BC7	H2B Clustered Histone 7	Protein Coding	8
56	H2BC6	H2B Clustered Histone 6	Protein Coding	8
57	H2BC9	H2B Clustered Histone 9	Protein Coding	8
58	H2BC10	H2B Clustered Histone 10	Protein Coding	8
59	H2BC4	H2B Clustered Histone 4	Protein Coding	8
60	H2BC17	H2B Clustered Histone 17	Protein Coding	8
61	H2BC21	H2B Clustered Histone 21	Protein Coding	8
62	H4C1	H4 Clustered Histone 1	Protein Coding	8
63	H4C4	H4 Clustered Histone 4	Protein Coding	8
64	H4C6	H4 Clustered Histone 6	Protein Coding	8
65	H4C12	H4 Clustered Histone 12	Protein Coding	8
66	H4C11	H4 Clustered Histone 11	Protein Coding	8
67	H4C3	H4 Clustered Histone 3	Protein Coding	8
68	H4C8	H4 Clustered Histone 8	Protein Coding	8
69	H4C2	H4 Clustered Histone 2	Protein Coding	8
70	H4C5	H4 Clustered Histone 5	Protein Coding	8
71	H4C13	H4 Clustered Histone 13	Protein Coding	8
72	RHNO1	RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1	Protein Coding	8
73	H4C14	H4 Clustered Histone 14	Protein Coding	8
74	BRIP1	BRCA1 Interacting DNA Helicase 1	Protein Coding	8
75	ATRIP	ATR Interacting Protein	Protein Coding	8
76	ABRAXAS1	Abraxas 1, BRCA1 A Complex Subunit	Protein Coding	8
77	H2BC12	H2B Clustered Histone 12	Protein Coding	8
78	HERC2	HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 2	Protein Coding	8
79	H2BC11	H2B Clustered Histone 11	Protein Coding	8
80	RNF8	Ring Finger Protein 8	Protein Coding	8
81	EXO1	Exonuclease 1	Protein Coding	8
82	BABAM2	BRISC And BRCA1 A Complex Member 2	Protein Coding	8
83	MDC1	Mediator Of DNA Damage Checkpoint 1	Protein Coding	8
84	CDK2	Cyclin Dependent Kinase 2	Protein Coding	7
85	RPS27A	Ribosomal Protein S27a	Protein Coding	7
86	CLSPN	Claspin	Protein Coding	7
87	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	7
88	UBB	Ubiquitin B	Protein Coding	7
89	UBC	Ubiquitin C	Protein Coding	7
90	SEM1	SEM1 26S Proteasome Subunit	Protein Coding	6
91	CHEK2	Checkpoint Kinase 2	Protein Coding	6
92	PPP4R2	Protein Phosphatase 4 Regulatory Subunit 2	Protein Coding	5
93	SIRT6	Sirtuin 6	Protein Coding	5
94	TIPIN	TIMELESS Interacting Protein	Protein Coding	5
95	PPP4C	Protein Phosphatase 4 Catalytic Subunit	Protein Coding	5
96	RAD52	RAD52 DNA Repair Protein	Protein Coding	5
97	RNF4	Ring Finger Protein 4	Protein Coding	5
98	SUMO2	Small Ubiquitin Like Modifier 2	Protein Coding	5
99	BRCA2	BRCA2 DNA Repair Associated	Protein Coding	5
100	UBE2I	Ubiquitin Conjugating Enzyme E2 I	Protein Coding	5
101	TIMELESS	Timeless Circadian Regulator	Protein Coding	5
102	TP53	Tumor Protein P53	Protein Coding	5
103	RAD51AP1	RAD51 Associated Protein 1	Protein Coding	4
104	POLD3	DNA Polymerase Delta 3, Accessory Subunit	Protein Coding	4
105	EME1	Essential Meiotic Structure-Specific Endonuclease 1	Protein Coding	4
106	EME2	Essential Meiotic Structure-Specific Endonuclease Subunit 2	Protein Coding	4
107	ERCC1	ERCC Excision Repair 1, Endonuclease Non-Catalytic Subunit	Protein Coding	4
108	ERCC4	ERCC Excision Repair 4, Endonuclease Catalytic Subunit	Protein Coding	4
109	SPIDR	Scaffold Protein Involved In DNA Repair	Protein Coding	4
110	ABL1	ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase	Protein Coding	4
111	GEN1	GEN1 Holliday Junction 5'' Flap Endonuclease	Protein Coding	4
112	PCNA	Proliferating Cell Nuclear Antigen	Protein Coding	4
113	POLK	DNA Polymerase Kappa	Protein Coding	4
114	RTEL1	Regulator Of Telomere Elongation Helicase 1	Protein Coding	4
115	POLE3	DNA Polymerase Epsilon 3, Accessory Subunit	Protein Coding	4
116	POLD1	DNA Polymerase Delta 1, Catalytic Subunit	Protein Coding	4
117	POLD2	DNA Polymerase Delta 2, Accessory Subunit	Protein Coding	4
118	POLE	DNA Polymerase Epsilon, Catalytic Subunit	Protein Coding	4
119	POLE2	DNA Polymerase Epsilon 2, Accessory Subunit	Protein Coding	4
120	POLH	DNA Polymerase Eta	Protein Coding	4
121	SLX1A	Structure-Specific Endonuclease Subunit SLX1A	Protein Coding	4
122	FIRRM	FIGNL1 Interacting Regulator Of Recombination And Mitosis	Protein Coding	4
123	POLE4	DNA Polymerase Epsilon 4, Accessory Subunit	Protein Coding	4
124	POLD4	DNA Polymerase Delta 4, Accessory Subunit	Protein Coding	4
125	RAD51	RAD51 Recombinase	Protein Coding	4
126	RAD51C	RAD51 Paralog C	Protein Coding	4
127	RAD51B	RAD51 Paralog B	Protein Coding	4
128	RAD51D	RAD51 Paralog D	Protein Coding	4
129	RFC1	Replication Factor C Subunit 1	Protein Coding	4
130	FIGNL1	Fidgetin Like 1	Protein Coding	4
131	XRCC2	X-Ray Repair Cross Complementing 2	Protein Coding	4
132	XRCC3	X-Ray Repair Cross Complementing 3	Protein Coding	4
133	SLX1B	Structure-Specific Endonuclease Subunit SLX1B	Protein Coding	4
134	PALB2	Partner And Localizer Of BRCA2	Protein Coding	4
135	MUS81	MUS81 Structure-Specific Endonuclease Subunit	Protein Coding	4
136	SLX4	SLX4 Structure-Specific Endonuclease Subunit	Protein Coding	4
137	PARP2	Poly(ADP-Ribose) Polymerase 2	Protein Coding	4
138	POLQ	DNA Polymerase Theta	Protein Coding	4
139	PARP1	Poly(ADP-Ribose) Polymerase 1	Protein Coding	4
140	FEN1	Flap Structure-Specific Endonuclease 1	Protein Coding	4
141	LIG3	DNA Ligase 3	Protein Coding	4
142	XRCC1	X-Ray Repair Cross Complementing 1	Protein Coding	4
143	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	4
144	SFN	Stratifin	Protein Coding	4
145	WEE1	WEE1 G2 Checkpoint Kinase	Protein Coding	4
146	YWHAB	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta	Protein Coding	4
147	YWHAE	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon	Protein Coding	4
148	YWHAG	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma	Protein Coding	4
149	YWHAH	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Eta	Protein Coding	4
150	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	4
151	CCNB1	Cyclin B1	Protein Coding	4
152	CDK1	Cyclin Dependent Kinase 1	Protein Coding	4
153	CDC25C	Cell Division Cycle 25C	Protein Coding	4
154	CENPS-CORT	CENPS-CORT Readthrough	Protein Coding	2
155	EYA4	EYA Transcriptional Coactivator And Phosphatase 4	Protein Coding	2
156	EYA1	EYA Transcriptional Coactivator And Phosphatase 1	Protein Coding	2
157	EYA2	EYA Transcriptional Coactivator And Phosphatase 2	Protein Coding	2
158	EYA3	EYA Transcriptional Coactivator And Phosphatase 3	Protein Coding	2
159	PAXIP1	PAX Interacting Protein 1	Protein Coding	2
160	KDM4B	Lysine Demethylase 4B	Protein Coding	2
161	XRCC6	X-Ray Repair Cross Complementing 6	Protein Coding	2
162	POLL	DNA Polymerase Lambda	Protein Coding	2
163	POLM	DNA Polymerase Mu	Protein Coding	2
164	APBB1	Amyloid Beta Precursor Protein Binding Family B Member 1	Protein Coding	2
165	CENPS	Centromere Protein S	Protein Coding	2
166	KPNA2	Karyopherin Subunit Alpha 2	Protein Coding	2
167	LIG4	DNA Ligase 4	Protein Coding	2
168	UBXN1	UBX Domain Protein 1	Protein Coding	2
169	TDP2	Tyrosyl-DNA Phosphodiesterase 2	Protein Coding	2
170	RIF1	Replication Timing Regulatory Factor 1	Protein Coding	2
171	PPP5C	Protein Phosphatase 5 Catalytic Subunit	Protein Coding	2
172	TDP1	Tyrosyl-DNA Phosphodiesterase 1	Protein Coding	2
173	PRKDC	Protein Kinase, DNA-Activated, Catalytic Subunit	Protein Coding	2
174	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	2
175	DCLRE1C	DNA Cross-Link Repair 1C	Protein Coding	2
176	SUMO1	Small Ubiquitin Like Modifier 1	Protein Coding	2
177	XRCC4	X-Ray Repair Cross Complementing 4	Protein Coding	2
178	XRCC5	X-Ray Repair Cross Complementing 5	Protein Coding	2
179	NHEJ1	Non-Homologous End Joining Factor 1	Protein Coding	2
180	BAP1	BRCA1 Associated Deubiquitinase 1	Protein Coding	2
181	SMARCA5	SNF2 Related Chromatin Remodeling ATPase 5	Protein Coding	2
182	BAZ1B	Bromodomain Adjacent To Zinc Finger Domain 1B	Protein Coding	2
183	KDM4A	Lysine Demethylase 4A	Protein Coding	2
184	RBX1	Ring-Box 1	Protein Coding	2
185	PSMD14	Proteasome 26S Subunit, Non-ATPase 14	Protein Coding	2
186	DBF4	DBF4-CDC7 Kinase Regulatory Subunit	Protein Coding	2
187	ADRM1	ADRM1 26S Proteasome Ubiquitin Receptor	Protein Coding	2
188	ORC6	Origin Recognition Complex Subunit 6	Protein Coding	2
189	ORC3	Origin Recognition Complex Subunit 3	Protein Coding	2
190	MCM2	Minichromosome Maintenance Complex Component 2	Protein Coding	2
191	MCM3	Minichromosome Maintenance Complex Component 3	Protein Coding	2
192	MCM4	Minichromosome Maintenance Complex Component 4	Protein Coding	2
193	MCM5	Minichromosome Maintenance Complex Component 5	Protein Coding	2
194	MCM6	Minichromosome Maintenance Complex Component 6	Protein Coding	2
195	MCM7	Minichromosome Maintenance Complex Component 7	Protein Coding	2
196	ORC1	Origin Recognition Complex Subunit 1	Protein Coding	2
197	ORC2	Origin Recognition Complex Subunit 2	Protein Coding	2
198	ORC4	Origin Recognition Complex Subunit 4	Protein Coding	2
199	ORC5	Origin Recognition Complex Subunit 5	Protein Coding	2
200	GTSE1	G2 And S-Phase Expressed 1	Protein Coding	2
201	MCM10	Minichromosome Maintenance 10 Replication Initiation Factor	Protein Coding	2
202	PSMA1	Proteasome 20S Subunit Alpha 1	Protein Coding	2
203	PSMA2	Proteasome 20S Subunit Alpha 2	Protein Coding	2
204	PSMA3	Proteasome 20S Subunit Alpha 3	Protein Coding	2
205	PSMA4	Proteasome 20S Subunit Alpha 4	Protein Coding	2
206	PSMA5	Proteasome 20S Subunit Alpha 5	Protein Coding	2
207	PSMA6	Proteasome 20S Subunit Alpha 6	Protein Coding	2
208	PSMA7	Proteasome 20S Subunit Alpha 7	Protein Coding	2
209	PSMB1	Proteasome 20S Subunit Beta 1	Protein Coding	2
210	PSMB2	Proteasome 20S Subunit Beta 2	Protein Coding	2
211	PSMB3	Proteasome 20S Subunit Beta 3	Protein Coding	2
212	PSMB4	Proteasome 20S Subunit Beta 4	Protein Coding	2
213	PSMB5	Proteasome 20S Subunit Beta 5	Protein Coding	2
214	PSMB6	Proteasome 20S Subunit Beta 6	Protein Coding	2
215	PSMB7	Proteasome 20S Subunit Beta 7	Protein Coding	2
216	PSMC1	Proteasome 26S Subunit, ATPase 1	Protein Coding	2
217	PSMC2	Proteasome 26S Subunit, ATPase 2	Protein Coding	2
218	PSMC3	Proteasome 26S Subunit, ATPase 3	Protein Coding	2
219	PSMC4	Proteasome 26S Subunit, ATPase 4	Protein Coding	2
220	PSMC5	Proteasome 26S Subunit, ATPase 5	Protein Coding	2
221	PSMC6	Proteasome 26S Subunit, ATPase 6	Protein Coding	2
222	PSMD1	Proteasome 26S Subunit, Non-ATPase 1	Protein Coding	2
223	PSMD2	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 2	Protein Coding	2
224	PSMD3	Proteasome 26S Subunit, Non-ATPase 3	Protein Coding	2
225	PSMD7	Proteasome 26S Subunit, Non-ATPase 7	Protein Coding	2
226	PSMD8	Proteasome 26S Subunit, Non-ATPase 8	Protein Coding	2
227	PSMD11	Proteasome 26S Subunit, Non-ATPase 11	Protein Coding	2
228	PSMD12	Proteasome 26S Subunit, Non-ATPase 12	Protein Coding	2
229	PSMD13	Proteasome 26S Subunit, Non-ATPase 13	Protein Coding	2
230	CDC7	Cell Division Cycle 7	Protein Coding	2
231	CDC45	Cell Division Cycle 45	Protein Coding	2
232	MCM8	Minichromosome Maintenance 8 Homologous Recombination Repair Factor	Protein Coding	2
233	PKMYT1	Protein Kinase, Membrane Associated Tyrosine/Threonine 1	Protein Coding	2
234	CCNB2	Cyclin B2	Protein Coding	2
235	PSMD6	Proteasome 26S Subunit, Non-ATPase 6	Protein Coding	2
236	CDC6	Cell Division Cycle 6	Protein Coding	2
237	CDC25A	Cell Division Cycle 25A	Protein Coding	2
238	ISY1-RAB43	ISY1-RAB43 Readthrough	Protein Coding	1
239	CDK7	Cyclin Dependent Kinase 7	Protein Coding	1
240	PIAS3	Protein Inhibitor Of Activated STAT 3	Protein Coding	1
241	MCRS1	Microspherule Protein 1	Protein Coding	1
242	PPIE	Peptidylprolyl Isomerase E	Protein Coding	1
243	MAD2L2	Mitotic Arrest Deficient 2 Like 2	Protein Coding	1
244	CETN2	Centrin 2	Protein Coding	1
245	COPS8	COP9 Signalosome Subunit 8	Protein Coding	1
246	ASCC3	Activating Signal Cointegrator 1 Complex Subunit 3	Protein Coding	1
247	COPS6	COP9 Signalosome Subunit 6	Protein Coding	1
248	COPS5	COP9 Signalosome Subunit 5	Protein Coding	1
249	POLI	DNA Polymerase Iota	Protein Coding	1
250	PNKP	Polynucleotide Kinase 3''-Phosphatase	Protein Coding	1
251	ERCC8	ERCC Excision Repair 8, CSA Ubiquitin Ligase Complex Subunit	Protein Coding	1
252	ALKBH2	AlkB Homolog 2, Alpha-Ketoglutarate Dependent Dioxygenase	Protein Coding	1
253	USP43	Ubiquitin Specific Peptidase 43	Protein Coding	1
254	INO80C	INO80 Complex Subunit C	Protein Coding	1
255	DDB1	Damage Specific DNA Binding Protein 1	Protein Coding	1
256	DDB2	Damage Specific DNA Binding Protein 2	Protein Coding	1
257	FAAP20	FA Core Complex Associated Protein 20	Protein Coding	1
258	CENPX	Centromere Protein X	Protein Coding	1
259	ERCC2	ERCC Excision Repair 2, TFIIH Core Complex Helicase Subunit	Protein Coding	1
260	ERCC3	ERCC Excision Repair 3, TFIIH Core Complex Helicase Subunit	Protein Coding	1
261	ERCC5	ERCC Excision Repair 5, Endonuclease	Protein Coding	1
262	ERCC6	ERCC Excision Repair 6, Chromatin Remodeling Factor	Protein Coding	1
263	FANCA	FA Complementation Group A	Protein Coding	1
264	FANCC	FA Complementation Group C	Protein Coding	1
265	FANCD2	FA Complementation Group D2	Protein Coding	1
266	FANCE	FA Complementation Group E	Protein Coding	1
267	FANCB	FA Complementation Group B	Protein Coding	1
268	FANCF	FA Complementation Group F	Protein Coding	1
269	FANCG	FA Complementation Group G	Protein Coding	1
270	ALKBH3	AlkB Homolog 3, Alpha-Ketoglutarate Dependent Dioxygenase	Protein Coding	1
271	FAN1	FANCD2 And FANCI Associated Nuclease 1	Protein Coding	1
272	SMUG1	Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1	Protein Coding	1
273	NEIL2	Nei Like DNA Glycosylase 2	Protein Coding	1
274	RCHY1	Ring Finger And CHY Zinc Finger Domain Containing 1	Protein Coding	1
275	POT1	Protection Of Telomeres 1	Protein Coding	1
276	TINF2	TERF1 Interacting Nuclear Factor 2	Protein Coding	1
277	PRPF19	Pre-MRNA Processing Factor 19	Protein Coding	1
278	INO80E	INO80 Complex Subunit E	Protein Coding	1
279	GPS1	G Protein Pathway Suppressor 1	Protein Coding	1
280	UBE2T	Ubiquitin Conjugating Enzyme E2 T	Protein Coding	1
281	MSH6	MutS Homolog 6	Protein Coding	1
282	GTF2H1	General Transcription Factor IIH Subunit 1	Protein Coding	1
283	GTF2H2	General Transcription Factor IIH Subunit 2	Protein Coding	1
284	GTF2H3	General Transcription Factor IIH Subunit 3	Protein Coding	1
285	GTF2H4	General Transcription Factor IIH Subunit 4	Protein Coding	1
286	TFPT	TCF3 Fusion Partner	Protein Coding	1
287	H2AC8	H2A Clustered Histone 8	Protein Coding	1
288	H2AC7	H2A Clustered Histone 7	Protein Coding	1
289	APEX1	Apurinic/Apyrimidinic Endodeoxyribonuclease 1	Protein Coding	1
290	POLN	DNA Polymerase Nu	Protein Coding	1
291	LIG1	DNA Ligase 1	Protein Coding	1
292	GTF2H5	General Transcription Factor IIH Subunit 5	Protein Coding	1
293	MGMT	O-6-Methylguanine-DNA Methyltransferase	Protein Coding	1
294	MLH1	MutL Homolog 1	Protein Coding	1
295	MNAT1	MNAT1 Component Of CDK Activating Kinase	Protein Coding	1
296	MPG	N-Methylpurine DNA Glycosylase	Protein Coding	1
297	MSH2	MutS Homolog 2	Protein Coding	1
298	MSH3	MutS Homolog 3	Protein Coding	1
299	MUTYH	MutY DNA Glycosylase	Protein Coding	1
300	H2AB1	H2A.B Variant Histone 1	Protein Coding	1
301	NFRKB	Nuclear Factor Related To KappaB Binding Protein	Protein Coding	1
302	NTHL1	Nth Like DNA Glycosylase 1	Protein Coding	1
303	OGG1	8-Oxoguanine DNA Glycosylase	Protein Coding	1
304	COPS7A	COP9 Signalosome Subunit 7A	Protein Coding	1
305	ASCC1	Activating Signal Cointegrator 1 Complex Subunit 1	Protein Coding	1
306	COPS4	COP9 Signalosome Subunit 4	Protein Coding	1
307	REV1	REV1 DNA Directed Polymerase	Protein Coding	1
308	DTL	Denticleless E3 Ubiquitin Protein Ligase Adapter	Protein Coding	1
309	PMS2	PMS1 Homolog 2, Mismatch Repair System Component	Protein Coding	1
310	POLB	DNA Polymerase Beta	Protein Coding	1
311	POLR2A	RNA Polymerase II Subunit A	Protein Coding	1
312	POLR2B	RNA Polymerase II Subunit B	Protein Coding	1
313	POLR2C	RNA Polymerase II Subunit C	Protein Coding	1
314	POLR2D	RNA Polymerase II Subunit D	Protein Coding	1
315	POLR2E	RNA Polymerase II, I And III Subunit E	Protein Coding	1
316	POLR2F	RNA Polymerase II, I And III Subunit F	Protein Coding	1
317	POLR2G	RNA Polymerase II Subunit G	Protein Coding	1
318	POLR2H	RNA Polymerase II, I And III Subunit H	Protein Coding	1
319	POLR2I	RNA Polymerase II Subunit I	Protein Coding	1
320	TERF2IP	TERF2 Interacting Protein	Protein Coding	1
321	POLR2J	RNA Polymerase II Subunit J	Protein Coding	1
322	POLR2K	RNA Polymerase II, I And III Subunit K	Protein Coding	1
323	POLR2L	RNA Polymerase II, I And III Subunit L	Protein Coding	1
324	INO80	INO80 Complex ATPase Subunit	Protein Coding	1
325	RNF111	Ring Finger Protein 111	Protein Coding	1
326	ALKBH5	AlkB Homolog 5, RNA Demethylase	Protein Coding	1
327	INO80D	INO80 Complex Subunit D	Protein Coding	1
328	ADPRS	ADP-Ribosylserine Hydrolase	Protein Coding	1
329	FANCL	FA Complementation Group L	Protein Coding	1
330	FANCI	FA Complementation Group I	Protein Coding	1
331	NEIL3	Nei Like DNA Glycosylase 3	Protein Coding	1
332	NPLOC4	NPL4 Homolog, Ubiquitin Recognition Factor	Protein Coding	1
333	H2AJ	H2A.J Histone	Protein Coding	1
334	RAD18	RAD18 E3 Ubiquitin Protein Ligase	Protein Coding	1
335	XAB2	XPA Binding Protein 2~Name Same As:- HGNC:14337	Protein Coding	1
336	ISY1	ISY1 Spliceosome Associated Protein	Protein Coding	1
337	WDR48	WD Repeat Domain 48	Protein Coding	1
338	UVSSA	UV Stimulated Scaffold Protein A	Protein Coding	1
339	FANCM	FA Complementation Group M	Protein Coding	1
340	RAD23A	RAD23 Nucleotide Excision Repair Protein A	Protein Coding	1
341	RAD23B	RAD23 Nucleotide Excision Repair Protein B	Protein Coding	1
342	REV3L	REV3 Like, DNA Directed Polymerase Zeta Catalytic Subunit	Protein Coding	1
343	ACTB	Actin Beta	Protein Coding	1
344	COPS7B	COP9 Signalosome Subunit 7B	Protein Coding	1
345	DCLRE1B	DNA Cross-Link Repair 1B	Protein Coding	1
346	ACD	ACD Shelterin Complex Subunit And Telomerase Recruitment Factor	Protein Coding	1
347	SUMO3	Small Ubiquitin Like Modifier 3	Protein Coding	1
348	TCEA1	Transcription Elongation Factor A1	Protein Coding	1
349	TDG	Thymine DNA Glycosylase	Protein Coding	1
350	TERF1	Telomeric Repeat Binding Factor 1	Protein Coding	1
351	TERF2	Telomeric Repeat Binding Factor 2	Protein Coding	1
352	H2AC19	H2A Clustered Histone 19	Protein Coding	1
353	UBA7	Ubiquitin Like Modifier Activating Enzyme 7	Protein Coding	1
354	UBE2B	Ubiquitin Conjugating Enzyme E2 B	Protein Coding	1
355	UFD1	Ubiquitin Recognition Factor In ER Associated Degradation 1	Protein Coding	1
356	UNG	Uracil DNA Glycosylase	Protein Coding	1
357	USP1	Ubiquitin Specific Peptidase 1	Protein Coding	1
358	VCP	Valosin Containing Protein	Protein Coding	1
359	XPA	XPA, DNA Damage Recognition And Repair Factor	Protein Coding	1
360	XPC	XPC Complex Subunit, DNA Damage Recognition And Repair Factor	Protein Coding	1
361	YY1	YY1 Transcription Factor	Protein Coding	1
362	TRIM25	Tripartite Motif Containing 25	Protein Coding	1
363	USP7	Ubiquitin Specific Peptidase 7	Protein Coding	1
364	FTO	FTO Alpha-Ketoglutarate Dependent Dioxygenase	Protein Coding	1
365	NEIL1	Nei Like DNA Glycosylase 1	Protein Coding	1
366	ACTR5	Actin Related Protein 5	Protein Coding	1
367	FAAP100	FA Core Complex Associated Protein 100	Protein Coding	1
368	ELL	Elongation Factor For RNA Polymerase II	Protein Coding	1
369	H2AC14	H2A Clustered Histone 14	Protein Coding	1
370	H2AC6	H2A Clustered Histone 6	Protein Coding	1
371	H2AC4	H2A Clustered Histone 4	Protein Coding	1
372	H2AC18	H2A Clustered Histone 18	Protein Coding	1
373	H2AC20	H2A Clustered Histone 20	Protein Coding	1
374	INO80B	INO80 Complex Subunit B	Protein Coding	1
375	SPRTN	SprT-Like N-Terminal Domain	Protein Coding	1
376	ASCC2	Activating Signal Cointegrator 1 Complex Subunit 2	Protein Coding	1
377	CUL4B	Cullin 4B	Protein Coding	1
378	CUL4A	Cullin 4A	Protein Coding	1
379	USP45	Ubiquitin Specific Peptidase 45	Protein Coding	1
380	PARG	Poly(ADP-Ribose) Glycohydrolase	Protein Coding	1
381	COPS3	COP9 Signalosome Subunit 3	Protein Coding	1
382	PIAS1	Protein Inhibitor Of Activated STAT 1	Protein Coding	1
383	ACTL6A	Actin Like 6A	Protein Coding	1
384	RUVBL1	RuvB Like AAA ATPase 1	Protein Coding	1
385	MBD4	Methyl-CpG Binding Domain 4, DNA Glycosylase	Protein Coding	1
386	CCNH	Cyclin H	Protein Coding	1
387	USP10	Ubiquitin Specific Peptidase 10	Protein Coding	1
388	FAAP24	FA Core Complex Associated Protein 24	Protein Coding	1
389	ZNF830	Zinc Finger Protein 830	Protein Coding	1
390	UBE2L6	Ubiquitin Conjugating Enzyme E2 L6	Protein Coding	1
391	COPS2	COP9 Signalosome Subunit 2	Protein Coding	1
392	ACTR8	Actin Related Protein 8	Protein Coding	1
393	H2AZ2	H2A.Z Variant Histone 2	Protein Coding	1
394	CHD1L	Chromodomain Helicase DNA Binding Protein 1 Like	Protein Coding	1
395	ISG15	ISG15 Ubiquitin Like Modifier	Protein Coding	1
396	AQR	Aquarius Intron-Binding Spliceosomal Factor	Protein Coding	1
397	PCLAF	PCNA Clamp Associated Factor	Protein Coding	1
398	DCLRE1A	DNA Cross-Link Repair 1A	Protein Coding	1
399	PMF1-BGLAP	PMF1-BGLAP Readthrough	Protein Coding	1
400	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
401	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	1
402	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	1
403	ANAPC10	Anaphase Promoting Complex Subunit 10	Protein Coding	1
404	NDC80	NDC80 Kinetochore Complex Component	Protein Coding	1
405	CENPA	Centromere Protein A	Protein Coding	1
406	CENPC	Centromere Protein C	Protein Coding	1
407	CENPE	Centromere Protein E	Protein Coding	1
408	CENPF	Centromere Protein F	Protein Coding	1
409	NUDC	Nuclear Distribution C, Dynein Complex Regulator	Protein Coding	1
410	KIF2C	Kinesin Family Member 2C	Protein Coding	1
411	UBE2C	Ubiquitin Conjugating Enzyme E2 C	Protein Coding	1
412	ZWINT	ZW10 Interacting Kinetochore Protein	Protein Coding	1
413	PMF1	Polyamine Modulated Factor 1	Protein Coding	1
414	ANAPC16	Anaphase Promoting Complex Subunit 16	Protein Coding	1
415	DYNLL2	Dynein Light Chain LC8-Type 2	Protein Coding	1
416	SPC24	SPC24 Component Of NDC80 Kinetochore Complex	Protein Coding	1
417	SGO2	Shugoshin 2	Protein Coding	1
418	SGO1	Shugoshin 1	Protein Coding	1
419	DYNC1H1	Dynein Cytoplasmic 1 Heavy Chain 1	Protein Coding	1
420	DYNC1I1	Dynein Cytoplasmic 1 Intermediate Chain 1	Protein Coding	1
421	DYNC1I2	Dynein Cytoplasmic 1 Intermediate Chain 2	Protein Coding	1
422	DYNC1LI2	Dynein Cytoplasmic 1 Light Intermediate Chain 2	Protein Coding	1
423	SKA1	Spindle And Kinetochore Associated Complex Subunit 1	Protein Coding	1
424	MAPRE1	Microtubule Associated Protein RP/EB Family Member 1	Protein Coding	1
425	CLASP2	Cytoplasmic Linker Associated Protein 2	Protein Coding	1
426	NUP160	Nucleoporin 160	Protein Coding	1
427	FBXW11	F-Box And WD Repeat Domain Containing 11	Protein Coding	1
428	CLASP1	Cytoplasmic Linker Associated Protein 1	Protein Coding	1
429	ITGB3BP	Integrin Subunit Beta 3 Binding Protein	Protein Coding	1
430	CDC26	Cell Division Cycle 26	Protein Coding	1
431	CENPI	Centromere Protein I	Protein Coding	1
432	ANAPC15	Anaphase Promoting Complex Subunit 15	Protein Coding	1
433	AHCTF1	AT-Hook Containing Transcription Factor 1	Protein Coding	1
434	NSL1	NSL1 Component Of MIS12 Kinetochore Complex	Protein Coding	1
435	ZNF385A	Zinc Finger Protein 385A	Protein Coding	1
436	UBE2S	Ubiquitin Conjugating Enzyme E2 S	Protein Coding	1
437	ANAPC2	Anaphase Promoting Complex Subunit 2	Protein Coding	1
438	ANAPC4	Anaphase Promoting Complex Subunit 4	Protein Coding	1
439	BIRC5	Baculoviral IAP Repeat Containing 5	Protein Coding	1
440	SKA2	Spindle And Kinetochore Associated Complex Subunit 2	Protein Coding	1
441	NUP43	Nucleoporin 43	Protein Coding	1
442	INCENP	Inner Centromere Protein	Protein Coding	1
443	KIF2A	Kinesin Family Member 2A	Protein Coding	1
444	CENPP	Centromere Protein P	Protein Coding	1
445	MAD2L1	Mitotic Arrest Deficient 2 Like 1	Protein Coding	1
446	MDM2	MDM2 Proto-Oncogene	Protein Coding	1
447	MDM4	MDM4 Regulator Of P53	Protein Coding	1
448	NUP98	Nucleoporin 98 And 96 Precursor	Protein Coding	1
449	PAFAH1B1	Platelet Activating Factor Acetylhydrolase 1b Regulatory Subunit 1	Protein Coding	1
450	DYNC1LI1	Dynein Cytoplasmic 1 Light Intermediate Chain 1	Protein Coding	1
451	PHF20	PHD Finger Protein 20	Protein Coding	1
452	ANAPC5	Anaphase Promoting Complex Subunit 5	Protein Coding	1
453	ANAPC7	Anaphase Promoting Complex Subunit 7	Protein Coding	1
454	ANAPC11	Anaphase Promoting Complex Subunit 11	Protein Coding	1
455	PLK1	Polo Like Kinase 1	Protein Coding	1
456	NDE1	NudE Neurodevelopment Protein 1	Protein Coding	1
457	ERCC6L	ERCC Excision Repair 6 Like, Spindle Assembly Checkpoint Helicase	Protein Coding	1
458	SPDL1	Spindle Apparatus Coiled-Coil Protein 1	Protein Coding	1
459	PPP1CC	Protein Phosphatase 1 Catalytic Subunit Gamma	Protein Coding	1
460	ZWILCH	Zwilch Kinetochore Protein	Protein Coding	1
461	CDCA8	Cell Division Cycle Associated 8	Protein Coding	1
462	PPP2CA	Protein Phosphatase 2 Catalytic Subunit Alpha	Protein Coding	1
463	PPP2CB	Protein Phosphatase 2 Catalytic Subunit Beta	Protein Coding	1
464	CENPQ	Centromere Protein Q	Protein Coding	1
465	PPP2R1A	Protein Phosphatase 2 Scaffold Subunit Aalpha	Protein Coding	1
466	PPP2R1B	Protein Phosphatase 2 Scaffold Subunit Abeta	Protein Coding	1
467	PPP2R5A	Protein Phosphatase 2 Regulatory Subunit B''Alpha	Protein Coding	1
468	PPP2R5B	Protein Phosphatase 2 Regulatory Subunit B''Beta	Protein Coding	1
469	PPP2R5C	Protein Phosphatase 2 Regulatory Subunit B''Gamma	Protein Coding	1
470	PPP2R5D	Protein Phosphatase 2 Regulatory Subunit B''Delta	Protein Coding	1
471	PPP2R5E	Protein Phosphatase 2 Regulatory Subunit B''Epsilon	Protein Coding	1
472	NUP133	Nucleoporin 133	Protein Coding	1
473	CENPN	Centromere Protein N	Protein Coding	1
474	RCC2	Regulator Of Chromosome Condensation 2	Protein Coding	1
475	PCBP4	Poly(RC) Binding Protein 4	Protein Coding	1
476	KNL1	Kinetochore Scaffold 1	Protein Coding	1
477	NUP107	Nucleoporin 107	Protein Coding	1
478	SPC25	SPC25 Component Of NDC80 Kinetochore Complex	Protein Coding	1
479	TAOK1	TAO Kinase 1	Protein Coding	1
480	RANBP2	RAN Binding Protein 2	Protein Coding	1
481	RANGAP1	Ran GTPase Activating Protein 1	Protein Coding	1
482	RPS27	Ribosomal Protein S27	Protein Coding	1
483	CLIP1	CAP-Gly Domain Containing Linker Protein 1	Protein Coding	1
484	SEC13	SEC13 Homolog, Nuclear Pore And COPII Component	Protein Coding	1
485	CENPK	Centromere Protein K	Protein Coding	1
486	COP1	COP1 E3 Ubiquitin Ligase	Protein Coding	1
487	ANAPC1	Anaphase Promoting Complex Subunit 1	Protein Coding	1
488	CENPH	Centromere Protein H	Protein Coding	1
489	SKP1	S-Phase Kinase Associated Protein 1	Protein Coding	1
490	BUB1	BUB1 Mitotic Checkpoint Serine/Threonine Kinase	Protein Coding	1
491	BUB1B	BUB1 Mitotic Checkpoint Serine/Threonine Kinase B	Protein Coding	1
492	UBE2D1	Ubiquitin Conjugating Enzyme E2 D1	Protein Coding	1
493	UBE2E1	Ubiquitin Conjugating Enzyme E2 E1	Protein Coding	1
494	XPO1	Exportin 1	Protein Coding	1
495	MIS12	MIS12 Kinetochore Complex Component	Protein Coding	1
496	CENPM	Centromere Protein M	Protein Coding	1
497	NUP37	Nucleoporin 37	Protein Coding	1
498	CENPO	Centromere Protein O	Protein Coding	1
499	CENPU	Centromere Protein U	Protein Coding	1
500	NUP85	Nucleoporin 85	Protein Coding	1
501	DSN1	DSN1 Component Of MIS12 Kinetochore Complex	Protein Coding	1
502	CENPT	Centromere Protein T	Protein Coding	1
503	B9D2	B9 Domain Containing 2	Protein Coding	1
504	NDEL1	NudE Neurodevelopment Protein 1 Like 1	Protein Coding	1
505	SEH1L	SEH1 Like Nucleoporin	Protein Coding	1
506	KIF18A	Kinesin Family Member 18A	Protein Coding	1
507	NUF2	NUF2 Component Of NDC80 Kinetochore Complex	Protein Coding	1
508	MAD1L1	Mitotic Arrest Deficient 1 Like 1	Protein Coding	1
509	CUL1	Cullin 1	Protein Coding	1
510	KIF2B	Kinesin Family Member 2B	Protein Coding	1
511	DYNLL1	Dynein Light Chain LC8-Type 1	Protein Coding	1
512	CDC23	Cell Division Cycle 23	Protein Coding	1
513	CDC16	Cell Division Cycle 16	Protein Coding	1
514	BTRC	Beta-Transducin Repeat Containing E3 Ubiquitin Protein Ligase	Protein Coding	1
515	CCNE1	Cyclin E1	Protein Coding	1
516	CCNE2	Cyclin E2	Protein Coding	1
517	CENPL	Centromere Protein L	Protein Coding	1
518	ZW10	Zw10 Kinetochore Protein	Protein Coding	1
519	BUB3	BUB3 Mitotic Checkpoint Protein	Protein Coding	1
520	AURKB	Aurora Kinase B	Protein Coding	1
521	KNTC1	Kinetochore Associated 1	Protein Coding	1
522	CKAP5	Cytoskeleton Associated Protein 5	Protein Coding	1
523	CDC20	Cell Division Cycle 20	Protein Coding	1
524	CDC27	Cell Division Cycle 27	Protein Coding	1

Disorders associated with HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Breast cancer	Enrichment	ABRAXAS1, ATM, BARD1, BLM, BRCA1, BRCA2, BRIP1, MRE11, NBN, PALB2, RAD50, RAD51, RAD51C, RAD51D, XRCC2, XRCC3	16.00
2	Ovarian cancer	Enrichment	ATM, BARD1, BLM, BRCA1, BRCA2, BRIP1, ERCC4, MRE11, NBN, PALB2, RAD50, RAD51C, RAD51D, WRN	16.00
3	Pancreatic cancer	Enrichment	ATM, BRCA1, BRCA2, BRIP1, ERCC4, NBN, PALB2, POLD1, RBBP8	16.00
4	Hereditary breast ovarian cancer syndrome	Enrichment	ATM, BARD1, BLM, BRCA1, BRCA2, BRIP1, MRE11, NBN, PALB2, RAD50, RAD51, RAD51B, RAD51C, RAD51D, XRCC2	16.00
5	Hereditary breast carcinoma	Enrichment	ATM, BARD1, BLM, BRCA1, BRCA2, BRIP1, NBN, PALB2, RAD50, RAD51, RAD51D	16.00
6	Inherited cancer-predisposing syndrome	Enrichment	ABRAXAS1, ATM, BARD1, BLM, BRCA1, BRCA2, BRIP1, MRE11, NBN, PALB2, POLD1, POLE, RAD50, RAD51B, RAD51C, RAD51D, XRCC2	16.00
7	Gastric cancer	Enrichment	ATM, BARD1, BRCA1, BRCA2, BRIP1, CHEK2, NBN, PALB2, RAD51C, RAD51D, TP53	16.00
8	Breast-ovarian cancer, familial 1	Enrichment	ATM, BRCA1, BRCA2, BRIP1, NBN, PALB2, RAD51C, RAD51D	16.00
9	Lynch syndrome 1	Enrichment	ATM, CHEK2, MLH1, MSH2, MSH6, PALB2, PMS2, RAD51D	11.06
10	Uterine corpus cancer	Enrichment	ATM, BRCA1, BRCA2, BRIP1, CHEK2, PALB2, RAD51C	10.90
11	Endometrial cancer	Enrichment	ATM, BARD1, BLM, BRCA1, BRCA2, CHEK2, MLH1, MSH2, MSH3, MSH6, MUTYH, PMS2, RAD51C	10.72
12	Colorectal cancer	Enrichment	ATM, BLM, BRCA1, BRCA2, BRIP1, CHEK2, FANCC, FANCE, FANCI, MLH1, MSH2, MSH6, MUTYH, PALB2, PMS2, POLD1, POLE, RAD51D, REV3L, RMI1, TP53	10.68
13	Fanconi anemia, complementation group a	Enrichment	BRCA1, BRCA2, BRIP1, ERCC4, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, MAD2L2, PALB2, RAD51, RAD51C, SLX4, UBE2T, XRCC2	10.66
14	Xeroderma pigmentosum, variant type	Enrichment	DDB2, ERCC2, ERCC3, ERCC4, ERCC5, POLH, XPA, XPC	10.45
15	Prostate cancer	Enrichment	ATM, BRCA1, BRCA2, CHEK2, NBN, PALB2, POLK, RAD51D, TP53	10.30
16	Meier-gorlin syndrome 1	Enrichment	CDC45, CDC6, MCM7, ORC1, ORC4, ORC6	9.38
17	Colonic benign neoplasm	Enrichment	ATM, CHEK2, MLH1, MRE11, MUTYH, PALB2	7.77
18	Familial colorectal cancer type x	Enrichment	ATM, BRCA2, CHEK2, MUTYH, POLD1, POLE	7.05
19	Seckel syndrome	Enrichment	ATR, ATRIP, CENPE, DNA2, NUP85, RBBP8	6.67
20	Tessadori-bicknell-van haaften neurodevelopmental syndrome 4	Enrichment	H2BC12, H4C1, H4C9	6.46
21	Mismatch repair cancer syndrome 1	Enrichment	MLH1, MSH2, MSH6, PMS2	6.44
22	Hepatoblastoma	Enrichment	BARD1, BRCA2, ERCC2, ERCC5, FANCA, MSH2, TP53	6.35
23	Lynch syndrome	Enrichment	CHEK2, FANCM, MLH1, MSH2, MSH6, PMS2	6.05
24	Rhabdomyosarcoma	Enrichment	BRCA1, BRCA2, MSH2, MSH6, PMS2, TP53	5.86
25	Xeroderma pigmentosum-cockayne syndrome complex	Enrichment	ERCC2, ERCC3, ERCC4, ERCC5	5.75
26	Li-fraumeni syndrome	Enrichment	CDKN2A, CHEK2, MDM2, TP53	5.56
27	Nijmegen breakage syndrome-like disorder	Enrichment	MRE11, RAD50	5.37
28	Cerebrooculofacioskeletal syndrome 1	Enrichment	ERCC1, ERCC2, ERCC5, ERCC6	5.28
29	Mosaic variegated aneuploidy syndrome	Enrichment	BUB1, BUB1B, BUB3, MAD1L1	4.90
30	Uv-sensitive syndrome	Enrichment	ERCC6, ERCC8, UVSSA	4.83
31	Melanoma, cutaneous malignant 1	Enrichment	ACD, BAP1, MGMT, POT1, TERF2IP	4.37
32	Tessadori-bicknell-van haaften neurodevelopmental syndrome 1	Enrichment	H4C1, H4C3	4.30
33	Tessadori-bicknell-van haaften neurodevelopmental syndrome 2	Enrichment	H4C1, H4C11	4.30
34	Li-fraumeni syndrome 1	Enrichment	CHEK2, TP53	4.30
35	Sarcoma	Enrichment	CHEK2, TP53	4.30
36	Microcephaly, growth restriction, and increased sister chromatid exchange 2	Enrichment	RMI2, TOP3A	4.30
37	Lynch syndrome 4	Enrichment	MSH2, MSH6, PMS2	4.24
38	Familial colorectal cancer	Enrichment	MLH1, MSH2, MUTYH, TP53	4.17
39	Myeloma, multiple	Enrichment	ATM, BAP1, BARD1, BRCA2, LIG4, TP53	4.16
40	Diffuse large b-cell lymphoma	Enrichment	BRCA2, CHEK2, NBN, PMS2, TP53	4.11
41	Diffuse midline glioma, h3 k27m-mutant	Enrichment	BRCA2, BRIP1	4.01
42	Inflammatory breast carcinoma	Enrichment	BRCA1, BRCA2	4.01
43	Bilateral breast cancer	Enrichment	BRCA1, BRCA2	4.01
44	Neuroendocrine tumor of pancreas	Enrichment	BRCA2, PALB2	4.01
45	Isolated growth hormone deficiency, type ia	Enrichment	BRCA2, DNA2, XRCC4	3.99
46	Cockayne syndrome a	Enrichment	ERCC4, ERCC6, ERCC8	3.85
47	Breast-ovarian cancer, familial 2	Enrichment	BRCA1, BRCA2, PMS2	3.85
48	Glioblastoma	Enrichment	ATM, MSH2, SLX4	3.85
49	Osteogenic sarcoma	Enrichment	CHEK2, TP53	3.83
50	Tessadori-bicknell-van haaften neurodevelopmental syndrome 3	Enrichment	H4C1, H4C5	3.83
51	Adenocarcinoma	Enrichment	ATM, TP53	3.83
52	Bone osteosarcoma	Enrichment	CHEK2, TP53	3.83
53	Lig4 syndrome	Enrichment	LIG4, XRCC4	3.81
54	Short stature, microcephaly, and endocrine dysfunction	Enrichment	XRCC2, XRCC4	3.81
55	Hepatocellular carcinoma	Enrichment	NBN, RAD50	3.78
56	Cockayne syndrome b	Enrichment	ERCC1, ERCC6, ERCC8	3.55
57	Clear cell renal cell carcinoma	Enrichment	ATM, BAP1, OGG1	3.55
58	Hoyeraal-hreidarsson syndrome	Enrichment	ACD, RTEL1, TINF2	3.55
59	Hereditary site-specific ovarian cancer syndrome	Enrichment	RAD51C, RAD51D	3.54
60	Polymerase proofreading-related polyposis	Enrichment	POLD1, POLE	3.54
61	Bladder cancer	Enrichment	ATM, BRCA1, CDKN1A, CDKN2A, TP53	3.51
62	Macroglossia	Enrichment	NSD2, TAOK1	3.36
63	Tumor predisposition syndrome 1	Enrichment	BAP1, BRCA2	3.33
64	Bap1 tumor predisposition syndrome	Enrichment	BAP1, BRCA2	3.33
65	Cockayne syndrome	Enrichment	ERCC4, ERCC6, ERCC8	3.32
66	Gliosarcoma	Enrichment	ATM, MGMT, MSH2, TP53	3.28
67	Chordoma	Enrichment	BRCA2, PALB2	3.24
68	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA1, BRCA2	3.24
69	Cholangiocarcinoma	Enrichment	BRCA1, BRCA2	3.24
70	Muir-torre syndrome	Enrichment	MLH1, MSH2	3.22
71	Xeroderma pigmentosum, complementation group a	Enrichment	XPA, XPC	3.22
72	Cockayne syndrome type 3	Enrichment	ERCC6, ERCC8	3.22
73	Giant cell glioblastoma	Enrichment	ATM, MGMT, MSH2, TP53	3.18
74	Genetic steroid-resistant nephrotic syndrome	Enrichment	NUP107, NUP133, NUP160, NUP37, NUP85	3.18
75	Primary ovarian insufficiency	Enrichment	CHEK2, ERCC1, NBN, RAD51C, SIRT6	3.07
76	Seckel syndrome 2	Enrichment	RBBP8	3.05
77	Glioma susceptibility 3	Enrichment	BRCA2	3.05
78	Pancreatic cancer 2	Enrichment	BRCA2	3.05
79	Jawad syndrome	Enrichment	RBBP8	3.05
80	Ataxia-telangiectasia-like disorder 1	Enrichment	MRE11	3.05
81	Spinocerebellar ataxia, autosomal recessive 26	Enrichment	XRCC1	3.05
82	Aicardi-goutieres syndrome 1	Enrichment	ATRIP, DCLRE1C	3.04
83	Lung cancer	Enrichment	BRCA1, CHEK2, ERCC6, MLH1, PALB2	2.99
84	Tumor predisposition syndrome 4	Enrichment	CHEK2	2.96
85	Developmental and epileptic encephalopathy 56	Enrichment	YWHAG	2.96
86	Leiomyosarcoma	Enrichment	CHEK2	2.96
87	Oocyte/zygote/embryo maturation arrest 21	Enrichment	CHEK1	2.96
88	Distal 17p13.3 microdeletion syndrome	Enrichment	YWHAE	2.96
89	Trichothiodystrophy	Enrichment	ERCC2, ERCC3, GTF2H5	2.95
90	Miller-dieker lissencephaly syndrome	Enrichment	PAFAH1B1, YWHAE	2.89
91	Chromosome 17p13.3, centromeric, duplication syndrome	Enrichment	PAFAH1B1, YWHAE	2.89
92	Leukemia, chronic lymphocytic	Enrichment	ATM, POT1, TP53	2.81
93	Fanconi anemia, complementation group d1	Enrichment	BRCA2	2.75
94	Mitochondrial dna depletion syndrome 20	Enrichment	LIG3	2.75
95	Congenital heart defects, multiple types, 3	Enrichment	CHEK2	2.66
96	Nijmegen breakage syndrome	Enrichment	NBN	2.58
97	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	ABL1, TP53	2.50
98	Tracheoesophageal fistula with or without esophageal atresia	Enrichment	BRCA2, BRIP1	2.48
99	Leukemia, acute lymphoblastic 3	Enrichment	ERCC4, PALB2	2.48
100	Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia	Enrichment	MRE11, PNKP	2.45
101	Isolated tracheo-esophageal fistula	Enrichment	BRCA2, BRIP1	2.38
102	Glioma susceptibility 1	Enrichment	BAP1, TP53	2.38
103	Ewing sarcoma	Enrichment	BAP1, SMARCA5	2.38
104	Mosaic variegated aneuploidy syndrome 1	Enrichment	BUB1B, MAD1L1	2.37
105	Primary autosomal recessive microcephaly	Enrichment	CENPE, KNL1, MCM7, NUP37	2.36
106	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	YWHAZ	2.35
107	Hemoglobin c disease	Enrichment	CHEK2	2.35
108	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	CHEK1	2.35
109	Kabuki syndrome 1	Enrichment	BRCA2	2.28
110	Renal cell carcinoma, nonpapillary	Enrichment	ATM, BAP1, OGG1	2.27
111	Endometrial stromal sarcoma	Enrichment	YWHAE	2.26
112	Fanconi anemia, complementation group d2	Enrichment	BRIP1, FANCD2	2.24
113	Lymphoma	Enrichment	PMS2, TP53	2.24
114	Adrenocortical carcinoma	Enrichment	CDKN2A, TP53	2.20
115	Omenn syndrome	Enrichment	DCLRE1C, LIG4	2.18
116	Wilms tumor 5	Enrichment	CHEK2	2.18
117	Kidney clear cell sarcoma	Enrichment	YWHAE	2.18
118	Premature menopause	Enrichment	ERCC1, NBN	2.15
119	Palmoplantar keratoderma, punctate type ii	Enrichment	BRCA1	2.15
120	Bloom syndrome	Enrichment	BLM	2.15
121	Fanconi anemia, complementation group j	Enrichment	BRIP1	2.15
122	Seckel syndrome 1	Enrichment	ATR	2.15
123	Seckel syndrome 8	Enrichment	DNA2	2.15
124	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 6	Enrichment	RPA1	2.15
125	Bone marrow failure syndrome 5	Enrichment	TP53	2.15
126	Papilloma of choroid plexus	Enrichment	TP53	2.15
127	Basal cell carcinoma 7	Enrichment	TP53	2.15
128	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 6	Enrichment	DNA2	2.15
129	Anaplastic thyroid carcinoma	Enrichment	TP53	2.15
130	Infant-type hemispheric glioma	Enrichment	BRCA1	2.15
131	Riddle syndrome	Enrichment	RNF168	2.15
132	Cutaneous telangiectasia and cancer syndrome, familial	Enrichment	ATR	2.15
133	Intellectual developmental disorder, autosomal recessive 38	Enrichment	HERC2	2.15
134	Endometrial serous adenocarcinoma	Enrichment	ATM	2.15
135	Ductal carcinoma in situ	Enrichment	TP53	2.15
136	Rauch-steindl syndrome	Enrichment	NSD2	2.15
137	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 5	Enrichment	TOP3A	2.15
138	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	2.15
139	Moyamoya angiopathy-short stature-facial dysmorphism-hypergonadotropic hypogonadism syndrome	Enrichment	BRCC3	2.15
140	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	2.15
141	Rothmund-thomson syndrome, type 4	Enrichment	DNA2	2.15
142	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	2.15
143	Morimoto-ryu-malicdan neuromuscular syndrome	Enrichment	RFC4	2.15
144	B-cell non-hodgkin lymphoma	Enrichment	ATM	2.15
145	Choroid plexus cancer	Enrichment	TP53	2.15
146	Pleomorphic xanthoastrocytoma	Enrichment	TP53	2.15
147	Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome	Enrichment	ATR	2.15
148	Primary peritoneal carcinoma	Enrichment	BRCA1	2.15
149	Advanced sleep phase syndrome, familial, 4	Enrichment	TIMELESS	2.15
150	Lethal brain and heart developmental defects	Enrichment	SIRT6	2.15
151	Polydactyly	Enrichment	BRCA2	2.10
152	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	LIG3	2.10
153	Severe combined immunodeficiency	Enrichment	DCLRE1C, LIG4, NHEJ1	2.10
154	Medulloblastoma	Enrichment	BRCA2, WRN	2.09
155	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A, CDKN1B	2.06
156	Aplastic anemia	Enrichment	NBN	2.05
157	Lissencephaly	Enrichment	DYNC1H1, NBN, PAFAH1B1	2.04
158	Lip and oral cavity carcinoma	Enrichment	ABL1, TP53	2.02
159	Leukemia, acute lymphoblastic	Enrichment	NBN	2.01
160	Cystic fibrosis with helicobacter pylori gastritis, megaloblastic anemia, and impaired intellectual development	Enrichment	POLE	2.01
161	Cerebrooculofacioskeletal syndrome 4	Enrichment	ERCC1	2.01
162	Colorectal cancer 10	Enrichment	POLD1	2.01
163	Fanconi anemia, complementation group p	Enrichment	SLX4	2.01
164	Mirror movements 2	Enrichment	RAD51	2.01
165	Colorectal cancer 12	Enrichment	POLE	2.01
166	Fanconi anemia, complementation group r	Enrichment	RAD51	2.01
167	Fanconi anemia, complementation group u	Enrichment	XRCC2	2.01
168	Immunodeficiency 120	Enrichment	POLD1	2.01
169	Premature ovarian failure 17	Enrichment	XRCC2	2.01
170	Spermatogenic failure 50	Enrichment	XRCC2	2.01
171	Xfe progeroid syndrome	Enrichment	ERCC4	2.01
172	Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome	Enrichment	POLD1	2.01
173	Ataxia-telangiectasia-like disorder 2	Enrichment	PCNA	2.01
174	Ovarian dysgenesis 9	Enrichment	SPIDR	2.01
175	Basal cell carcinoma	Enrichment	PALB2	2.01
176	Immunodeficiency 122	Enrichment	POLD3	2.01
177	Esophageal atresia/tracheoesophageal fistula	Enrichment	BRCA2, BRIP1, POLR2B	1.97
178	Dyskeratosis congenita	Enrichment	POT1, RTEL1, TINF2	1.97
179	Melanoma	Enrichment	CHEK2	1.96
180	Isolated split hand-split foot malformation	Enrichment	BTRC, SEM1	1.95
181	Lactose intolerance, adult type	Enrichment	MCM6	1.94
182	Meier-gorlin syndrome 3	Enrichment	ORC6	1.94
183	Meier-gorlin syndrome 2	Enrichment	ORC4	1.94
184	Immunodeficiency 80 with or without congenital cardiomyopathy	Enrichment	MCM10	1.94
185	Neurodevelopmental disorder with microcephaly, hypotonia, and absent language	Enrichment	PSMB1	1.94
186	Stankiewicz-isidor syndrome	Enrichment	PSMD12	1.94
187	Anisometropia	Enrichment	MCM7	1.94
188	Deafness, cataract, impaired intellectual development, and polyneuropathy	Enrichment	PSMC3	1.94
189	Immunodeficiency 54	Enrichment	MCM4	1.94
190	Deafness, autosomal dominant 70	Enrichment	MCM2	1.94
191	Meier-gorlin syndrome 8	Enrichment	MCM5	1.94
192	Premature ovarian failure 10	Enrichment	MCM8	1.94
193	Meier-gorlin syndrome 5	Enrichment	CDC6	1.94
194	Meier-gorlin syndrome 7	Enrichment	CDC45	1.94
195	Specific learning disability	Enrichment	YWHAG	1.92
196	Immunodeficiency 124, severe combined	Enrichment	NHEJ1	1.90
197	Melanoma, uveal 2	Enrichment	BAP1	1.90
198	Otofaciocervical syndrome 1	Enrichment	EYA1	1.90
199	Spinocerebellar ataxia, autosomal recessive 23	Enrichment	TDP2	1.90
200	Orofacial cleft 10	Enrichment	SUMO1	1.90
201	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1	Enrichment	TDP1	1.90
202	Immunodeficiency 26 with or without neurologic abnormalities	Enrichment	PRKDC	1.90
203	Microphthalmia/coloboma 13	Enrichment	NHEJ1	1.90
204	Wilms tumor 1	Enrichment	BRCA2	1.88
205	Adrenocortical carcinoma, hereditary	Enrichment	TP53	1.85
206	Skin/hair/eye pigmentation, variation in, 1	Enrichment	HERC2	1.85
207	Moyamoya disease 4 with short stature, hypergonadotropic hypogonadism, and facial dysmorphism	Enrichment	BRCC3	1.85
208	Cervical cancer	Enrichment	TP53	1.85
209	Rothmund-thomson syndrome, type 2	Enrichment	DNA2	1.85
210	Lymphoma, hodgkin, classic	Enrichment	TP53	1.85
211	Neurodevelopmental disorder with dysmorphic facies, sleep disturbance, and brain abnormalities	Enrichment	KAT5	1.85
212	Fanconi anemia, complementation group s	Enrichment	BRCA1	1.85
213	Cardiac valvular dysplasia, x-linked	Enrichment	ATM	1.85
214	Werner syndrome	Enrichment	WRN	1.85
215	Pancreatic cancer 4	Enrichment	BRCA1	1.85
216	Ovarian cancer 1	Enrichment	BRIP1	1.85
217	Microcephaly and chorioretinopathy, autosomal recessive, 3	Enrichment	TP53BP1	1.85
218	Congenital fibrosarcoma	Enrichment	TP53	1.85
219	High grade glioma	Enrichment	ATM	1.85
220	Cervix carcinoma	Enrichment	TP53	1.85
221	Hodgkin's lymphoma	Enrichment	TP53	1.85
222	T-cell prolymphocytic leukemia	Enrichment	ATM	1.85
223	Fissured tongue	Enrichment	NSD2	1.85
224	Peritoneum cancer	Enrichment	BRCA1	1.85
225	Microcephaly and chorioretinopathy 3	Enrichment	TP53BP1	1.85
226	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	1.85
227	Submucosal cleft palate	Enrichment	UBB	1.85
228	Cleft hard palate	Enrichment	UBB	1.85
229	Nk-cell enteropathy	Enrichment	CHEK2	1.85
230	Fanconi anemia, complementation group c	Enrichment	DCLRE1B, FANCC	1.81
231	Galloway-mowat syndrome	Enrichment	NUP107, NUP133	1.75
232	Polymicrogyria	Enrichment	DYNC1H1, PSMC3	1.75
233	Xeroderma pigmentosum, complementation group f	Enrichment	ERCC4	1.71
234	Fanconi anemia, complementation group n	Enrichment	PALB2	1.71
235	Melanoma, cutaneous malignant 6	Enrichment	XRCC3	1.71
236	Intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies	Enrichment	POLE	1.71
237	Neurodevelopmental disorder with hypotonia, speech delay, and dysmorphic facies	Enrichment	POLK	1.71
238	Dyskeratosis congenita, autosomal recessive 5	Enrichment	RTEL1	1.71
239	Pancreatic cancer 3	Enrichment	PALB2	1.71
240	Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome	Enrichment	RFC1	1.71
241	Congenital heart defects and skeletal malformations syndrome	Enrichment	ABL1	1.71
242	Intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, genital anomalies, and immunodeficiency	Enrichment	POLE	1.71
243	Autosomal dominant dyskeratosis congenita 4	Enrichment	RTEL1	1.71
244	Fanconi anemia, complementation group q	Enrichment	ERCC4	1.71
245	Xeroderma pigmentosum group f	Enrichment	ERCC4	1.71
246	Facial dysmorphism, immunodeficiency, livedo, and short stature	Enrichment	POLE	1.71
247	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 3	Enrichment	RTEL1	1.71
248	Complex neurodevelopmental disorder	Enrichment	BAP1, H4C3, H4C5, H4C9, KDM4B	1.70
249	Accelerated tumor formation	Enrichment	MDM2	1.68
250	Cortical dysplasia, complex, with other brain malformations 3	Enrichment	KIF2A	1.68
251	Premature chromatid separation trait	Enrichment	BUB1B	1.68
252	Developmental delay with or without intellectual impairment or behavioral abnormalities	Enrichment	TAOK1	1.68
253	Nephrotic syndrome, type 19	Enrichment	NUP160	1.68
254	Oocyte/zygote/embryo maturation arrest 14	Enrichment	CDC20	1.68
255	Lessel-kubisch syndrome	Enrichment	MDM2	1.68
256	Bone marrow failure syndrome 6	Enrichment	MDM4	1.68
257	Neurodevelopmental, jaw, eye, and digital syndrome	Enrichment	FBXW11	1.68
258	Houge-janssens syndrome 4	Enrichment	PPP2R5C	1.68
259	Galloway-mowat syndrome 8	Enrichment	NUP133	1.68
260	Ferguson-bonni neurodevelopmental syndrome	Enrichment	ANAPC7	1.68
261	Houge-janssens syndrome 2	Enrichment	PPP2R1A	1.68
262	Microcephaly 4, primary, autosomal recessive	Enrichment	KNL1	1.68
263	Microcephaly 24, primary, autosomal recessive	Enrichment	NUP37	1.68
264	Microhydranencephaly	Enrichment	NDE1	1.68
265	Galloway-mowat syndrome 7	Enrichment	NUP107	1.68
266	Rothmund-thomson syndrome, type 1	Enrichment	ANAPC1	1.68
267	Neuroendocrine tumor	Enrichment	CDKN1B	1.68
268	Lissencephaly 4 with microcephaly	Enrichment	NDE1	1.68
269	Meckel syndrome, type 10	Enrichment	B9D2	1.68
270	Nephrotic syndrome, type 11	Enrichment	NUP107	1.68
271	Dync1h1-related disorders	Enrichment	DYNC1H1	1.68
272	Microcephaly 13, primary, autosomal recessive	Enrichment	CENPE	1.68
273	Ovarian dysgenesis 6	Enrichment	NUP107	1.68
274	Short stature and microcephaly with genital anomalies	Enrichment	CENPT	1.68
275	Nephrotic syndrome, type 18	Enrichment	NUP133	1.68
276	Neurodevelopmental disorder with microcephaly and structural brain anomalies	Enrichment	DYNC1I2	1.68
277	Hydranencephaly	Enrichment	NDE1	1.68
278	Microcephaly 30, primary, autosomal recessive	Enrichment	BUB1	1.68
279	Cdkn2a cancer predisposition	Enrichment	CDKN2A	1.68
280	Mosaic variegated aneuploidy syndrome 7 with inflammation and tumor predisposition	Enrichment	MAD1L1	1.68
281	Nde1-related microhydranencephaly	Enrichment	NDE1	1.68
282	Familial acute necrotizing encephalopathy	Enrichment	RANBP2	1.68
283	Lissencephaly due to lis1 mutation	Enrichment	PAFAH1B1	1.68
284	Ppp2r1a-related neurodevelopmental disorder	Enrichment	PPP2R1A	1.68
285	Ataxia-telangiectasia	Enrichment	ATM	1.68
286	Vasculopathy, retinal, with cerebral leukoencephalopathy and systemic manifestations	Enrichment	ATRIP	1.68
287	Polycythemia vera	Enrichment	ATM	1.68
288	Chilblain lupus 1	Enrichment	ATRIP	1.68
289	Nasopharyngeal carcinoma	Enrichment	TP53	1.68
290	Koolen-de vries syndrome	Enrichment	ATM	1.68
291	Chilblain lupus	Enrichment	ATRIP	1.68
292	Atypical teratoid rhabdoid tumor	Enrichment	TP53	1.68
293	Anaplastic astrocytoma	Enrichment	TP53	1.68
294	Squamous cell carcinoma	Enrichment	TP53	1.68
295	Childhood apraxia of speech	Enrichment	RFC3	1.68
296	Uvula, bifid	Enrichment	UBB	1.67
297	Cleft soft palate	Enrichment	UBB	1.67
298	Birk-aharoni syndrome	Enrichment	PSMC1	1.64
299	Proteasome-associated autoinflammatory syndrome 3	Enrichment	PSMB4	1.64
300	17q24.2 microdeletion syndrome	Enrichment	PSMD12	1.64
301	Torticollis	Enrichment	ACTL6A	1.61
302	Baraitser-winter syndrome 1	Enrichment	ACTB	1.61
303	Melanoma, uveal 1	Enrichment	MBD4	1.61
304	Xeroderma pigmentosum, complementation group b	Enrichment	ERCC3	1.61
305	Inclusion body myopathy with early-onset paget disease with or without frontotemporal dementia 1	Enrichment	VCP	1.61
306	Ataxia-oculomotor apraxia 4	Enrichment	PNKP	1.61
307	Fanconi anemia, complementation group t	Enrichment	UBE2T	1.61
308	Immunodeficiency 38 with basal ganglia calcification	Enrichment	ISG15	1.61
309	Ruijs-aalfs syndrome	Enrichment	SPRTN	1.61
310	Fanconi anemia, complementation group g	Enrichment	FANCG	1.61
311	Tumor predisposition syndrome 3	Enrichment	POT1	1.61
312	Fanconi anemia, complementation group v	Enrichment	MAD2L2	1.61
313	White-kernohan syndrome	Enrichment	DDB1	1.61
314	Fanconi anemia, complementation group b	Enrichment	FANCB	1.61
315	Spermatogenic failure 28	Enrichment	FANCM	1.61
316	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 8	Enrichment	POT1	1.61
317	Premature ovarian failure 15	Enrichment	FANCM	1.61
318	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	1.61
319	Lynch syndrome 2	Enrichment	MLH1	1.61
320	Xeroderma pigmentosum, complementation group d	Enrichment	ERCC2	1.61
321	Trichothiodystrophy 2, photosensitive	Enrichment	ERCC3	1.61
322	Growth retardation, developmental delay, and facial dysmorphism	Enrichment	FTO	1.61
323	Xeroderma pigmentosum group b	Enrichment	ERCC3	1.61
324	Becker nevus syndrome	Enrichment	ACTB	1.61
325	Dystonia-deafness syndrome 1	Enrichment	ACTB	1.61
326	Cerebrooculofacioskeletal syndrome 2	Enrichment	ERCC2	1.61
327	High-grade astrocytoma with piloid features	Enrichment	POT1	1.61
328	Dyskeratosis congenita, autosomal recessive 8	Enrichment	DCLRE1B	1.61
329	Cerebroretinal microangiopathy with calcifications and cysts 3	Enrichment	POT1	1.61
330	Uv-sensitive syndrome 3	Enrichment	UVSSA	1.61
331	Spinal muscular atrophy with congenital bone fractures 2	Enrichment	ASCC1	1.61
332	Trichothiodystrophy 3, photosensitive	Enrichment	GTF2H5	1.61
333	Familial adenomatous polyposis 3	Enrichment	NTHL1	1.61
334	Immunodeficiency 96	Enrichment	LIG1	1.61
335	Body mass index quantitative trait locus 14	Enrichment	FTO	1.61
336	Frontotemporal dementia and/or amyotrophic lateral sclerosis 6	Enrichment	VCP	1.61
337	Fanconi anemia, complementation group l	Enrichment	FANCL	1.61
338	Mismatch repair cancer syndrome 2	Enrichment	MSH2	1.61
339	Leber congenital amaurosis 19	Enrichment	USP45	1.61
340	Mismatch repair cancer syndrome 4	Enrichment	PMS2	1.61
341	Neurodegeneration, childhood-onset, stress-induced, with variable ataxia and seizures	Enrichment	ADPRS	1.61
342	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	1.61
343	Multisystem proteinopathy	Enrichment	VCP	1.61
344	Rectal benign neoplasm	Enrichment	MSH2	1.61
345	Autosomal recessive spastic paraplegia type 60	Enrichment	WDR48	1.61
346	Tumor predisposition syndrome 2	Enrichment	MBD4	1.61
347	Baraitser-winter syndrome	Enrichment	ACTB	1.61
348	Intellectual developmental disorder, autosomal recessive 81	Enrichment	ASCC3	1.61
349	Adult-onset distal myopathy due to vcp mutation	Enrichment	VCP	1.61
350	Pituitary cancer	Enrichment	PMS2	1.61
351	Ascending colon cancer	Enrichment	MSH2	1.61
352	Fanconi anemia, complementation group x	Enrichment	FAAP100	1.61
353	Ovarian cyst	Enrichment	MSH2	1.61
354	Congenital smooth muscle hamartoma	Enrichment	ACTB	1.61
355	Xeroderma pigmentosum group d	Enrichment	ERCC2	1.61
356	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	1.61
357	Chromosome 2q35 duplication syndrome	Enrichment	NHEJ1	1.60
358	Dubowitz syndrome	Enrichment	LIG4	1.60
359	Severe combined immunodeficiency with sensitivity to ionizing radiation	Enrichment	DCLRE1C	1.60
360	Intellectual developmental disorder, autosomal dominant 65	Enrichment	KDM4B	1.60
361	Branchiootic syndrome	Enrichment	EYA1	1.60
362	Branchiootic syndrome 1	Enrichment	EYA1	1.60
363	Ocular melanoma	Enrichment	BAP1	1.60
364	Kury-isidor syndrome	Enrichment	BAP1	1.60
365	Otofaciocervical syndrome	Enrichment	EYA1	1.60
366	Microcephalic primordial dwarfism-insulin resistance syndrome	Enrichment	XRCC4	1.60
367	Williams-beuren syndrome	Enrichment	BAZ1B, RFC2	1.59
368	Small cell cancer of the lung	Enrichment	TP53	1.55
369	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	1.55
370	Mantle cell lymphoma	Enrichment	ATM	1.55
371	Lung sarcomatoid carcinoma	Enrichment	TP53	1.55
372	Embryonal rhabdomyosarcoma	Enrichment	TP53	1.55
373	Autosomal recessive chorioretinopathy-microcephaly syndrome	Enrichment	TP53BP1	1.55
374	Thrombotic microangiopathy	Enrichment	ATRIP	1.55
375	Oculomotor apraxia	Enrichment	ATM	1.55
376	Dyskeratosis congenita, x-linked	Enrichment	RTEL1	1.53
377	Breast-ovarian cancer, familial 3	Enrichment	RAD51C	1.53
378	Breast-ovarian cancer, familial 4	Enrichment	RAD51D	1.53
379	Fanconi anemia, complementation group o	Enrichment	RAD51C	1.53
380	Breast-ovarian cancer, familial 5	Enrichment	PALB2	1.53
381	Cutis laxa, autosomal recessive, type ib	Enrichment	MUS81	1.53
382	T-cell acute lymphoblastic leukemia	Enrichment	ABL1	1.53
383	Cerebral palsy	Enrichment	BRCA2	1.47
384	Proteasome-associated autoinflammatory syndrome 1	Enrichment	PSMB4	1.47
385	Proteosome-associated autoinflammatory syndrome	Enrichment	PSMB4	1.47
386	Thyroid hemiagenesis	Enrichment	PSMD3	1.47
387	Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1	Enrichment	ATRIP	1.46
388	Rhabdomyosarcoma 2	Enrichment	TP53	1.46
389	Hypoglycemia	Enrichment	NSD2	1.46
390	Vascular dementia	Enrichment	ATRIP	1.46
391	Acute megakaryocytic leukemia	Enrichment	TP53	1.46
392	Mesothelioma, malignant	Enrichment	BAP1	1.43
393	Niemann-pick disease, type a	Enrichment	APBB1	1.43
394	Deafness, autosomal dominant 10	Enrichment	EYA4	1.43
395	Cardiomyopathy, dilated, 1j	Enrichment	EYA4	1.43
396	Niemann-pick disease, type b	Enrichment	APBB1	1.43
397	Ehlers-danlos syndrome, kyphoscoliotic type, 1	Enrichment	DCLRE1C	1.43
398	Arthrogryposis multiplex congenita 6	Enrichment	RIF1	1.43
399	Plod1-related kyphoscoliotic ehlers-danlos syndrome	Enrichment	DCLRE1C	1.43
400	Isolated anophthalmia-microphthalmia syndrome	Enrichment	NHEJ1	1.43
401	Mirror movements 1	Enrichment	RAD51	1.41
402	Hutchinson-gilford progeria syndrome	Enrichment	ERCC4	1.41
403	Epilepsy, progressive myoclonic, 4, with or without renal failure	Enrichment	RTEL1	1.41
404	Combined oxidative phosphorylation deficiency 32	Enrichment	EME2	1.41
405	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	ABL1	1.41
406	Combined oxidative phosphorylation deficiency 24	Enrichment	RTEL1	1.41
407	Aortic aneurysm, familial thoracic 4	Enrichment	NDE1	1.38
408	Melanoma-astrocytoma syndrome	Enrichment	CDKN2A	1.38
409	Spinal muscular atrophy, lower extremity-predominant, 1, autosomal dominant	Enrichment	DYNC1H1	1.38
410	Microcephalic osteodysplastic primordial dwarfism, type i	Enrichment	CLASP1	1.38
411	Stromme syndrome	Enrichment	CENPF	1.38
412	Lowry-wood syndrome	Enrichment	CLASP1	1.38
413	Nephronophthisis-like nephropathy 1	Enrichment	RANGAP1	1.38
414	Lissencephaly 1	Enrichment	PAFAH1B1	1.38
415	Melanoma, cutaneous malignant 2	Enrichment	CDKN2A	1.38
416	Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies	Enrichment	DYNC1I2	1.38
417	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	1.38
418	Houge-janssens syndrome 1	Enrichment	PPP2R5D	1.38
419	Roifman syndrome	Enrichment	CLASP1	1.38
420	Cortical dysplasia, complex, with other brain malformations 13	Enrichment	DYNC1H1	1.38
421	Megacystis-microcolon-intestinal hypoperistalsis syndrome 2	Enrichment	NDE1	1.38
422	Nephrotic syndrome, type 17	Enrichment	NUP85	1.38
423	Neurodevelopmental disorder with developmental delay and with or without motor or speech delay	Enrichment	TAOK1	1.38
424	Spinal muscular atrophy with lower extremity predominant	Enrichment	DYNC1H1	1.38
425	Melanoma-pancreatic cancer syndrome	Enrichment	CDKN2A	1.38
426	Body mass index quantitative trait locus 19	Enrichment	CENPO	1.38
427	Charcot-marie-tooth disease, axonal, type 2o	Enrichment	DYNC1H1	1.38
428	Visceral myopathy 2	Enrichment	NDE1	1.38
429	Degenerative disc disease	Enrichment	CENPP	1.38
430	Methylmalonic aciduria and homocystinuria, cbll type	Enrichment	CENPT	1.38
431	Rnu4atac-opathy	Enrichment	CLASP1	1.38
432	Chronic atrial and intestinal dysrhythmia	Enrichment	SGO1	1.38
433	Diamond-blackfan anemia 17	Enrichment	RPS27	1.38
434	Houge-janssens syndrome 3	Enrichment	PPP2CA	1.38
435	Primary mediastinal large b-cell lymphoma	Enrichment	XPO1	1.38
436	Acute necrotizing encephalopathy of childhood	Enrichment	RANBP2	1.38
437	Wolf-hirschhorn syndrome	Enrichment	NSD2	1.38
438	Breast adenocarcinoma	Enrichment	TP53	1.38
439	Astigmatism	Enrichment	MCM7	1.34
440	Enophthalmos	Enrichment	MCM7	1.34
441	Microcephaly	Enrichment	DYNC1H1, MCM7, NBN, NUF2, PSMC3, YWHAG	1.34
442	Pituitary stalk interruption syndrome	Enrichment	FANCA, FANCG	1.34
443	Autosomal recessive cerebellar ataxia	Enrichment	ERCC4	1.31
444	Esophageal cancer	Enrichment	TP53	1.31
445	Prader-willi syndrome	Enrichment	HERC2	1.31
446	Squamous cell carcinoma, head and neck	Enrichment	TP53	1.31
447	Renal cell carcinoma, papillary, 1	Enrichment	ATM	1.31
448	Essential thrombocythemia	Enrichment	TP53	1.31
449	Gallbladder cancer	Enrichment	TP53	1.31
450	Burkitt lymphoma	Enrichment	PMS2	1.31
451	Revesz syndrome	Enrichment	TINF2	1.31
452	Ovarian germ cell cancer	Enrichment	FANCM	1.31
453	Xeroderma pigmentosum, complementation group c	Enrichment	XPC	1.31
454	Vacterl association, x-linked, with or without hydrocephalus	Enrichment	FANCL	1.31
455	Xeroderma pigmentosum, complementation group e	Enrichment	DDB2	1.31
456	Intellectual developmental disorder, x-linked, syndromic, cabezas type	Enrichment	CUL4B	1.31
457	Fanconi anemia, complementation group i	Enrichment	FANCI	1.31
458	Amyotrophic lateral sclerosis 6 with or without frontotemporal dementia	Enrichment	VCP	1.31
459	Waardenburg syndrome, type 4c	Enrichment	POLR2F	1.31
460	Familial adenomatous polyposis 2	Enrichment	MUTYH	1.31
461	Charcot-marie-tooth disease, axonal, type 2b2	Enrichment	PNKP	1.31
462	Gabriele-de vries syndrome	Enrichment	YY1	1.31
463	Immunodeficiency, common variable, 15	Enrichment	RUVBL1	1.31
464	Congenital disorder of deglycosylation 2	Enrichment	NEIL1	1.31
465	Pettigrew syndrome	Enrichment	CUL4B	1.31
466	Mitochondrial complex i deficiency, nuclear type 10	Enrichment	ERCC8	1.31
467	Dyskeratosis congenita, autosomal dominant 3	Enrichment	TINF2	1.31
468	Interstitial nephritis, karyomegalic	Enrichment	FAN1	1.31
469	Intellectual developmental disorder, x-linked, syndromic, pilorge type	Enrichment	FANCB	1.31
470	Fanconi anemia, complementation group e	Enrichment	FANCE	1.31
471	Charcot-marie-tooth disease type 2b2	Enrichment	PNKP	1.31
472	Microcephaly, seizures, and developmental delay	Enrichment	PNKP	1.31
473	Oligodendroglioma	Enrichment	POT1	1.31
474	Peripheral demyelinating neuropathy, central dysmyelination, waardenburg syndrome, and hirschsprung disease	Enrichment	POLR2F	1.31
475	Immunodeficiency with hyper-igm, type 5	Enrichment	UNG	1.31
476	Developmental and epileptic encephalopathy 78	Enrichment	YY1	1.31
477	Insulinoma	Enrichment	YY1	1.31
478	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB	1.31
479	Hao-fountain syndrome	Enrichment	USP7	1.31
480	Anaplastic oligodendroglioma	Enrichment	POT1	1.31
481	Mismatch repair cancer syndrome 3	Enrichment	MSH6	1.31
482	Xeroderma pigmentosum group c	Enrichment	XPC	1.31
483	Prenatal-onset spinal muscular atrophy with congenital bone fractures	Enrichment	ASCC1	1.31
484	Vacterl with hydrocephalus	Enrichment	FANCB	1.31
485	Malignant germ cell tumor of ovary	Enrichment	FANCM	1.31
486	Xeroderma pigmentosum group e	Enrichment	DDB2	1.31
487	Spastic paraplegia-paget disease of bone syndrome	Enrichment	VCP	1.31
488	Branchiooculofacial syndrome	Enrichment	EYA1	1.31
489	Nemaline myopathy 2	Enrichment	RIF1	1.31
490	Autosomal dominant non-syndromic intellectual disability	Enrichment	YWHAZ	1.27
491	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.26
492	2q23.1 microduplication syndrome	Enrichment	ORC4	1.25
493	Farsightedness	Enrichment	MCM7	1.25
494	Isolated congenital microcephaly	Enrichment	INO80, PNKP	1.24
495	Pulmonary fibrosis	Enrichment	RTEL1	1.24
496	Undetermined early-onset epileptic encephalopathy	Enrichment	YWHAG	1.22
497	Niemann-pick disease, type c1	Enrichment	APBB1	1.21
498	Niemann-pick disease	Enrichment	APBB1	1.21
499	Spondyloepiphyseal dysplasia congenita	Enrichment	CLASP1	1.21
500	Methylmalonic aciduria and homocystinuria, cblx type	Enrichment	CENPT	1.21
501	Band heterotopia	Enrichment	PAFAH1B1	1.21
502	Ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	RANBP2	1.21
503	Dedifferentiated liposarcoma	Enrichment	MDM2	1.21
504	Tricuspid valve insufficiency	Enrichment	NDE1	1.21
505	Well-differentiated liposarcoma	Enrichment	MDM2	1.21
506	Adult hepatocellular carcinoma	Enrichment	TP53	1.21
507	Primary hyperaldosteronism	Enrichment	TP53	1.21
508	Ventricular septal defect	Enrichment	NSD2	1.21
509	Developmental dysplasia of the hip 1	Enrichment	PSMC3	1.17
510	Patent ductus arteriosus	Enrichment	PSMC3	1.17
511	Leukemia, chronic myeloid	Enrichment	ABL1	1.17
512	Moyamoya angiopathy	Enrichment	ABL1	1.17
513	Aicardi-goutieres syndrome	Enrichment	ATRIP	1.16
514	Retinoblastoma	Enrichment	FANCM	1.14
515	Waardenburg syndrome, type 2a	Enrichment	POLR2F	1.14
516	Combined cellular and humoral immune defects with granulomas	Enrichment	INO80	1.14
517	Trichothiodystrophy 1, photosensitive	Enrichment	ERCC2	1.14
518	De sanctis-cacchione syndrome	Enrichment	ERCC6	1.14
519	Xeroderma pigmentosum, complementation group g	Enrichment	ERCC5	1.14
520	Uv-sensitive syndrome 1	Enrichment	ERCC6	1.14
521	Spastic paraplegia 7, autosomal recessive	Enrichment	MUTYH	1.14
522	Uv-sensitive syndrome 2	Enrichment	ERCC8	1.14
523	Dyskeratosis congenita, autosomal dominant 6	Enrichment	ACD	1.14
524	Lynch syndrome 5	Enrichment	MSH6	1.14
525	Cerebrooculofacioskeletal syndrome 3	Enrichment	ERCC5	1.14
526	Neurodevelopmental disorder with progressive spasticity and brain abnormalities	Enrichment	RUVBL1	1.14
527	Familial adenomatous polyposis 4	Enrichment	MSH3	1.14
528	Fanconi anemia, complementation group f	Enrichment	FANCF	1.14
529	Inclusion body myopathy with paget disease of bone and frontotemporal dementia	Enrichment	VCP	1.14
530	Umbilical hernia	Enrichment	ACTL6A	1.14
531	Wieacker-wolff syndrome	Enrichment	CCNH	1.14
532	Premature ovarian failure 11	Enrichment	ERCC6	1.14
533	Cellular ependymoma	Enrichment	MSH2	1.14
534	Tanycytic ependymoma	Enrichment	MSH2	1.14
535	Papillary ependymoma	Enrichment	MSH2	1.14
536	Intellectual developmental disorder with dysmorphic facies and behavioral abnormalities	Enrichment	MSH6	1.14
537	Colon adenocarcinoma	Enrichment	MSH6	1.14
538	Xeroderma pigmentosum group g	Enrichment	ERCC5	1.14
539	Clear cell ependymoma	Enrichment	MSH2	1.14
540	Melanoma, uveal	Enrichment	BAP1	1.14
541	Branchiootorenal syndrome 1	Enrichment	EYA1	1.14
542	Leukemia, acute myeloid	Enrichment	FANCD2, RTEL1, TP53	1.13
543	Immune deficiency disease	Enrichment	ATM	1.12
544	Myelodysplastic syndrome	Enrichment	TP53	1.12
545	Ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	RANBP2	1.09
546	Cystinuria	Enrichment	CENPF	1.09
547	Ciliary dyskinesia, primary, 29	Enrichment	CENPF	1.09
548	Ectodermal dysplasia	Enrichment	RANBP2	1.09
549	Mitral valve insufficiency	Enrichment	NDE1	1.09
550	Primary hyperparathyroidism	Enrichment	CDKN1B	1.09
551	Branchiootorenal syndrome	Enrichment	EYA1	1.07
552	Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly	Enrichment	NSD2	1.05
553	Neural tube defects	Enrichment	RAD9B	1.05
554	Clubfoot	Enrichment	NSD2	1.05
555	Protein-deficiency anemia	Enrichment	NSD2	1.05
556	Lung cancer susceptibility 3	Enrichment	TP53	1.02
557	Periventricular nodular heterotopia	Enrichment	BRCA1	1.02
558	Cataract	Enrichment	WRN	1.02
559	Gaucher disease, type i	Enrichment	MSH6	1.02
560	Deafness, autosomal recessive 1a	Enrichment	ERCC8	1.02
561	Erythrocytosis, familial, 2	Enrichment	FANCD2	1.02
562	Pilomatrixoma	Enrichment	MUTYH	1.02
563	Macular degeneration, age-related, 5	Enrichment	ERCC6	1.02
564	Barrett esophagus	Enrichment	ASCC1	1.02
565	Aminoacylase 1 deficiency	Enrichment	ACTB	1.02
566	Developmental and epileptic encephalopathy 12	Enrichment	PNKP	1.02
567	Spastic paraplegia 47, autosomal recessive	Enrichment	DCLRE1B	1.02
568	Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalities	Enrichment	POLR2A	1.02
569	Craniopharyngioma	Enrichment	ERCC2	1.02
570	Gjb2-related autosomal recessive nonsyndromic hearing loss	Enrichment	ERCC8	1.02
571	Vacterl association	Enrichment	FANCL	1.02
572	Benign ependymoma	Enrichment	MSH2	1.02
573	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.02
574	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	RANBP2	1.00
575	Deafness, autosomal recessive 63	Enrichment	ANAPC15	1.00
576	Chromosome 15q11.2 deletion syndrome	Enrichment	PAFAH1B1	1.00
577	Lissencephaly 2	Enrichment	NDE1	1.00
578	Spinal muscular atrophy	Enrichment	DYNC1H1	1.00
579	Autosomal recessive hypohidrotic ectodermal dysplasia syndrome	Enrichment	RANBP2	1.00
580	Combined immunodeficiency	Enrichment	POLD1	0.99
581	Combined t cell and b cell immunodeficiency	Enrichment	POLD1	0.99
582	Combined t and b cell immunodeficiency	Enrichment	POLD1	0.99
583	Renal agenesis, bilateral	Enrichment	EYA1	0.97
584	46 xx gonadal dysgenesis	Enrichment	SPIDR	0.95
585	Syndromic intellectual disability	Enrichment	NSD2	0.94
586	Capillary malformations, congenital	Enrichment	CCNH	0.93
587	Moebius syndrome	Enrichment	REV3L	0.93
588	Dementia, lewy body	Enrichment	VCP	0.93
589	Vater/vacterl association	Enrichment	FANCL	0.93
590	Von hippel-lindau syndrome	Enrichment	FANCD2	0.93
591	Hypogonadotropic hypogonadism 1 with or without anosmia	Enrichment	POLR2F	0.93
592	Familial adenomatous polyposis 1	Enrichment	MUTYH	0.93
593	Charcot-marie-tooth disease, axonal, type 2e	Enrichment	VCP	0.93
594	Polyneuropathy	Enrichment	ERCC5	0.93
595	Nemaline myopathy	Enrichment	RIF1	0.93
596	Inflammatory myofibroblastic tumor	Enrichment	RANBP2	0.92
597	Intestinal pseudo-obstruction	Enrichment	NDE1	0.92
598	Lung squamous cell carcinoma	Enrichment	CDKN2A	0.92
599	Heart disease	Enrichment	ABL1	0.89
600	Mitochondrial dna depletion syndrome 4a	Enrichment	RANBP2	0.86
601	Dyskeratosis congenita, autosomal dominant 1	Enrichment	TINF2	0.86
602	Klippel-trenaunay-weber syndrome	Enrichment	CCNH	0.86
603	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	CCNH	0.86
604	Waardenburg syndrome, type 4a	Enrichment	POLR2F	0.86
605	Hemangioma, capillary infantile	Enrichment	CCNH	0.86
606	Basal cell carcinoma 1	Enrichment	CCNH	0.86
607	Inguinal hernia	Enrichment	ACTL6A	0.86
608	Waardenburg syndrome	Enrichment	POLR2F	0.86
609	Meningioma	Enrichment	BAP1	0.85
610	Diamond-blackfan anemia 1	Enrichment	TP53	0.82
611	Interstitial lung disease 2	Enrichment	RTEL1	0.81
612	Mitochondrial dna depletion syndrome 4b	Enrichment	RANBP2	0.81
613	Perrault syndrome	Enrichment	SGO2	0.81
614	Waardenburg syndrome, type 1	Enrichment	POLR2F	0.80
615	Waardenburg syndrome, type 2e	Enrichment	POLR2F	0.80
616	Capillary malformation-arteriovenous malformation 1	Enrichment	CCNH	0.80
617	Dyskeratosis congenita, autosomal dominant 2	Enrichment	TINF2	0.80
618	Hereditary hemorrhagic telangiectasia	Enrichment	CCNH	0.80
619	Hereditary clear cell renal cell carcinoma	Enrichment	OGG1	0.80
620	Parkinson's disease	Enrichment	RFC1	0.76
621	Diamond-blackfan anemia	Enrichment	RPS27, TP53	0.76
622	Polycystic liver disease	Enrichment	CDC25A	0.75
623	Autosomal dominant polycystic liver disease	Enrichment	CDC25A	0.75
624	Gastroesophageal reflux	Enrichment	ACTL6A	0.74
625	Patent foramen ovale	Enrichment	PSMC3	0.73
626	Inflammatory bowel disease 1	Enrichment	ERCC2	0.70
627	Arteriovenous malformation	Enrichment	CCNH	0.70
628	Progressive non-fluent aphasia	Enrichment	VCP	0.70
629	Hypotrichosis simplex	Enrichment	ERCC2	0.70
630	Behavioral variant of frontotemporal dementia	Enrichment	VCP	0.70
631	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ABL1	0.69
632	Azoospermia	Enrichment	MCM8	0.68
633	Parkinson disease, late-onset	Enrichment	RFC1	0.67
634	Frontotemporal dementia and/or amyotrophic lateral sclerosis 1	Enrichment	VCP	0.66
635	Myopathy, x-linked, with excessive autophagy	Enrichment	CCNH	0.66
636	Focal segmental glomerulosclerosis	Enrichment	EYA1	0.65
637	Myocardial infarction	Enrichment	PSMA6	0.65
638	Microphthalmia	Enrichment	MCM7	0.65
639	Short-rib thoracic dysplasia 3 with or without polydactyly	Enrichment	DYNC1H1	0.65
640	Pectus excavatum	Enrichment	ERCC5	0.62
641	Cardiomyopathy, familial hypertrophic, 9	Enrichment	PMS2	0.62
642	Atrial heart septal defect	Enrichment	ACTL6A	0.62
643	Interatrial communication	Enrichment	ACTL6A	0.62
644	Systemic lupus erythematosus	Enrichment	ATRIP	0.62
645	Tooth agenesis	Enrichment	SUMO1	0.62
646	Type 2 diabetes mellitus	Enrichment	WRN	0.59
647	Digeorge syndrome	Enrichment	UFD1	0.59
648	Rare genetic deafness	Enrichment	EYA1, EYA4	0.58
649	Muscular dystrophy	Enrichment	RIF1	0.58
650	Hypertrophic cardiomyopathy	Enrichment	NSD2	0.58
651	Myopia	Enrichment	NDE1	0.56
652	Alzheimer's disease	Enrichment	VCP	0.56
653	Oligospermia	Enrichment	SPRTN	0.56
654	Body mass index quantitative trait locus 11	Enrichment	CENPO, NUDC	0.55
655	Thrombocytopenia	Enrichment	NSD2	0.54
656	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	CENPP, MCM2	0.52
657	Corpus callosum, agenesis of	Enrichment	ERCC2	0.51
658	Isolated corpus callosum agenesis	Enrichment	ERCC2	0.51
659	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	ERCC2	0.51
660	Male infertility with spermatogenesis disorder	Enrichment	FANCM	0.51
661	Charcot-marie-tooth disease type 4	Enrichment	DYNC1H1	0.50
662	Alzheimer disease, familial, 1	Enrichment	VCP	0.46
663	Early infantile developmental and epileptic encephalopathy	Enrichment	PNKP	0.44
664	Non-syndromic genetic deafness	Enrichment	EYA4	0.44
665	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	VCP	0.42
666	Congenital myopathy	Enrichment	ASCC3	0.42
667	Leukodystrophy	Enrichment	ERCC2	0.41
668	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	FANCM, XRCC2	0.39
669	Centronuclear myopathy	Enrichment	ASCC1	0.39
670	Spastic ataxia	Enrichment	ERCC4	0.39
671	Nonsyndromic hearing loss	Enrichment	EYA4	0.39
672	Cardiomyopathy, dilated, 1g	Enrichment	PMS2	0.37
673	Kallmann syndrome	Enrichment	POLR2F	0.36
674	Hirschsprung disease 1	Enrichment	NUP98	0.34
675	Meckel syndrome, type 1	Enrichment	B9D2	0.34
676	Severe covid-19	Enrichment	CENPF	0.34
677	Mitochondrial disease	Enrichment	TOP3A	0.34
678	Isolated joubert syndrome	Enrichment	B9D2	0.33
679	Peripheral nervous system disease	Enrichment	DYNC1H1	0.31
680	Neuropathy	Enrichment	DYNC1H1	0.31
681	Leigh syndrome, nuclear	Enrichment	EME2	0.30
682	Nephronophthisis	Enrichment	INCENP	0.30
683	Leigh disease	Enrichment	EME2	0.28
684	Myopathy	Enrichment	DYNC1H1	0.24
685	Charcot-marie-tooth disease	Enrichment	DYNC1H1	0.24
686	Fetal akinesia deformation sequence 1	Enrichment	ASCC1	0.22
687	Mitochondrial complex i deficiency, nuclear type 1	Enrichment	ERCC8	0.21
688	Distal arthrogryposis	Enrichment	ASCC1	0.19
689	Joubert syndrome 1	Enrichment	B9D2	0.18
690	Autosomal recessive non-syndromic intellectual disability	Enrichment	CLIP1	0.15
691	Congenital nervous system abnormality	Enrichment	ERCC8, PNKP	0.13
692	Nervous system disease	Enrichment	ERCC8, PNKP	0.13
693	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	VCP	0.12
694	Hereditary retinal dystrophy	Enrichment	ATRIP	0.06
695	Fundus dystrophy	Enrichment	ATRIP	0.06
696	Autism spectrum disorder	Enrichment	DYNC1H1	0.04
697	Leber plus disease	Enrichment	USP45	0.04
698	Retinitis pigmentosa	Enrichment	TFPT	0.00

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

Pathway Network for HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

Pathway network for the HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) SuperPath

Member Pathways for HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

Pathways in the HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) SuperPath

Gene overlap in member pathways for HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) SuperPath

Associated Genes for HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

Associated Disorders for HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

Disorders associated with HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) SuperPath

STRING Interaction Network for HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

Sources for HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)